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Ito Tomohiro  伊藤 智彦

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ITO Tomohiro  伊藤 智彦

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Researcher Number 60391067
Other IDs
Affiliation (Current) 2025: 国立研究開発法人国立環境研究所, 環境リスク・健康領域, 主任研究員
Affiliation (based on the past Project Information) *help 2024: 国立研究開発法人国立環境研究所, 環境リスク・健康領域, 主任研究員
2021 – 2022: 国立研究開発法人国立環境研究所, 環境リスク・健康領域, 主任研究員
2020: 国立研究開発法人国立環境研究所, 環境リスク・健康研究センター, 主任研究員
2016 – 2018: 国立研究開発法人国立環境研究所, 環境リスク・健康研究センター, 主任研究員
2011: 独立行政法人国立環境研究所, 環境健康研究センター, 主任研究員
2010: 独立行政法人国立環境研究所, 環境健康研究領域, 主任研究員
Review Section/Research Field
Principal Investigator
Basic Section 63040:Environmental impact assessment-related / Environmental impact assessment / Hygiene
Except Principal Investigator
Basic Section 63030:Chemical substance influence on environment-related / Environmental risk control and evaluation
Keywords
Principal Investigator
多能性幹細胞 / iPS細胞 / in vitro / 化学物質 / 神経発達毒性 / グリア細胞 / 殺虫剤 / マウスES細胞 / 環境汚染物質 / 発達神経毒性 … More / 呼吸器 / 発生・分化 / 大気汚染物質 / 基底膜 / 肺上皮細胞 / 基底膜基質 / ディーゼル排気微粒子 / ペルオキシゾーム増殖剤応答性受容体 / エストロゲン受容体 / フタル酸エステル / 造血幹細胞 … More
Except Principal Investigator
細胞 / 脳 / ナノプラスチック / 化学物質 / スクリーニング / 環境 / バイオインフォマティクス / 生殖発生毒性 / 予防対策 / in vitro / エピジェネティクス / 放射線 / 毒性予測 / 幹細胞 / 有害物質 / 影響評価 / 化学物質管理 / エピジェネティック Less
  • Research Projects

    (5 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (16 People)
  •  Comprehensive Study of the Developmental Neurotoxic Effects of Nanoplastics

    • Principal Investigator
      前川 文彦
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 63030:Chemical substance influence on environment-related
    • Research Institution
      National Institute for Environmental Studies
  •  Investigation of new evaluation system for neurodevelopmental toxicity using multifaceted indicesPrincipal Investigator

    • Principal Investigator
      Ito Tomohiro
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 63040:Environmental impact assessment-related
    • Research Institution
      National Institute for Environmental Studies
  •  Induction of iPS cell-derived lung epithelial cells by using the basement membrane substratumPrincipal Investigator

    • Principal Investigator
      Ito Tomohiro
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Environmental impact assessment
    • Research Institution
      National Institute for Environmental Studies
  •  Detection of chemical substances with epigenetic activity to protect environmental risk by the adverse outcome pathway approach

    • Principal Investigator
      Sone Hideko
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Environmental risk control and evaluation
    • Research Institution
      Yokohama College of Pharmacy
      National Institute for Environmental Studies
  •  Effects of environmental chemicals on the hematopoiesis of iPS cellsPrincipal Investigator

    • Principal Investigator
      ITO Tomohiro
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Hygiene
    • Research Institution
      National Institute for Environmental Studies

All 2022 2021 2019 2018 2017 2016 2015

All Journal Article Presentation

  • [Journal Article] Epigenetic Effects of Exposure to Insecticide on Early Differentiation of Mouse Embryonic Stem Cells2019

    • Author(s)
      Wang W, Otsuka S, Nansai H, Ito T, Abe K, Nakao Y, Ohgane J, Yoneda M, Sone H
    • Journal Title

      bioRxiv

      Volume: なし Pages: 628487-628487

    • DOI

      10.1101/628487

    • Data Source
      KAKENHI-PROJECT-15H01749
  • [Journal Article] Expression of human mutant cyclin dependent kinase 4, Cyclin D and telomerase extends the life span but does not immortalize fibroblasts derived from loggerhead sea turtle (Caretta caretta).2018

    • Author(s)
      Fukuda T, Eitsuka T, Donai K, Kurita M, Saito T, Okamoto H, Kinoshita K, Katayama M, Nitto H, Uchida T, Onuma M, Sone H, Inoue-Murayama M, Kiyono T.
    • Journal Title

      Sci Rep

      Volume: 8 Issue: 1 Pages: 9229-9229

    • DOI

      10.1038/s41598-018-27271-x

    • NAID

      120006979734

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07803, KAKENHI-PROJECT-17K19426, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PROJECT-15H01749, KAKENHI-PROJECT-17H03624, KAKENHI-PLANNED-25118005, KAKENHI-PROJECT-26252064, KAKENHI-PROJECT-16H05801
  • [Journal Article] Cell Type-Specific Survey of Epigenetic Modifications by Tandem Chromatin Immunoprecipitation Sequencing2018

    • Author(s)
      Mito Mari、Kadota Mitsutaka、Tanaka Kaori、Furuta Yasuhide、Abe Kuniya、Iwasaki Shintaro、Nakagawa Shinichi
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 1143-1143

    • DOI

      10.1038/s41598-018-19494-9

    • NAID

      120006398777

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K14644, KAKENHI-PUBLICLY-16H01225, KAKENHI-PLANNED-26113005, KAKENHI-PROJECT-26250025, KAKENHI-PROJECT-17H03604, KAKENHI-PROJECT-18K19312, KAKENHI-PROJECT-15H01749, KAKENHI-PUBLICLY-17H05679, KAKENHI-PROJECT-17H04998
  • [Journal Article] Evidence of exposure to chemicals and heavy metals during pregnancy in Japanese women2017

    • Author(s)
      Maekawa Ryo、Ito Rie、Iwasaki Yusuke、Saito Koichi、Akutsu Kazuhiko、Takatori Satoshi、Ishii Rie、Kondo Fumio、Arai Yoshikazu、Ohgane Jun、Shiota Kunio、Makino Tsunehisa、Sugino Norihiro
    • Journal Title

      Reproductive Medicine and Biology

      Volume: 16 Issue: 4 Pages: 337-348

    • DOI

      10.1002/rmb2.12049

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H01749, KAKENHI-PROJECT-15H02480, KAKENHI-PROJECT-16K16193
  • [Journal Article] Conserved role of Ovo in germline development in mouse and Drosophila.2017

    • Author(s)
      Hayashi, M., Shinozuka, Y., Shigenobu, S., Sato, M., Sugimoto, M., Ito, S., Abe, K., Kobayashi, S.
    • Journal Title

      Scientific Report

      Volume: 6 Issue: 1 Pages: 40056-40056

    • DOI

      10.1038/srep40056

    • NAID

      120007135169

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-16H01225, KAKENHI-PROJECT-15H01749, KAKENHI-PROJECT-26250025, KAKENHI-PROJECT-16H05233, KAKENHI-PROJECT-25712034, KAKENHI-PROJECT-16K14644, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25114002
  • [Journal Article] Methylation Analysis of DNA Mismatch Repair Genes Using DNA Derived from the Peripheral Blood of Patients with Endometrial Cancer: Epimutation in Endometrial Carcinogenesis.2016

    • Author(s)
      Takeda T, Banno K, Yanokura M, Adachi M, Iijima M, Kunitomi H, Nakamura K, Iida M, Nogami Y, Umene K, Masuda K, Kobayashi Y, Yamagami W, Hirasawa A, Tominaga E, Susumu N, Aoki D
    • Journal Title

      Genes (Basel)

      Volume: 7 Issue: 10 Pages: 86-97

    • DOI

      10.3390/genes7100086

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H01749, KAKENHI-PROJECT-15K10730, KAKENHI-PROJECT-16K11156
  • [Journal Article] A genetically encoded FRET probe to detect intranucleosomal histone H3K9 or H3K14 acetylation using BRD4, a BET family member2016

    • Author(s)
      Nakaoka, S., Sasaki, K., Ito, A., Nakao, Y., and Yoshida, M.
    • Journal Title

      ACS Chem. Biol.

      Volume: 11 Issue: 3 Pages: 729-733

    • DOI

      10.1021/cb501046t

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26221204, KAKENHI-PROJECT-25303008, KAKENHI-PROJECT-15H01749
  • [Journal Article] Putative Epimutagens in Maternal Peripheral and Cord Blood Samples Identified Using Human Induced Pluripotent Stem Cells.2015

    • Author(s)
      Arai Y, Hayakawa K, Arai D, Ito R, Iwasaki Y, Saito K, Akutsu K, Takatori S, Ishii R, Hayashi R, Izumi S, Sugino N, Kondo F, Horie M, Nakazawa H, Makino T, Hirosawa M, Shiota K, Ohgane J.
    • Journal Title

      Biomed Res Int.

      Volume: 2015 Pages: 1-13

    • DOI

      10.1155/2015/876047

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07836, KAKENHI-PROJECT-25450472, KAKENHI-PROJECT-15H01749, KAKENHI-PROJECT-26252052
  • [Presentation] 神経系の発達過程に着目した神経発達毒性のin vitroアプローチ2022

    • Author(s)
      伊藤智彦,曽根秀子
    • Organizer
      第49回日本毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-20K12199
  • [Presentation] マウス多能性幹細胞系における殺虫剤の神経発達毒性と機序の解析2022

    • Author(s)
      伊藤智彦,曽根秀子
    • Organizer
      日本薬学会 第142年会
    • Data Source
      KAKENHI-PROJECT-20K12199
  • [Presentation] マウスES細胞を用いた殺虫剤による神経発達毒性の解析2021

    • Author(s)
      伊藤智彦、曽根秀子
    • Organizer
      日本薬学会
    • Data Source
      KAKENHI-PROJECT-20K12199
  • [Presentation] 環境汚染物質の毒性研究の現状と今後の展開2021

    • Author(s)
      伊藤智彦
    • Organizer
      第29回環境化学討論会
    • Data Source
      KAKENHI-PROJECT-20K12199
  • [Presentation] 多能性幹細胞を用いたエストロゲン様物質のエピジェネティック毒性に関する研究2018

    • Author(s)
      大塚 悟史、南齋 ひろ子、伊藤 智彦、中尾 洋一、曽根 秀子
    • Organizer
      第21回環境ホルモン学会研究発表会
    • Data Source
      KAKENHI-PROJECT-15H01749
  • [Presentation] 多能性幹細胞を用いたエピジェネティック毒性物質スクリーニング2018

    • Author(s)
      大塚 悟史、南齋 ひろ子、伊藤 智彦、阿部 訓也、中尾 洋一、曽根 秀子
    • Organizer
      第45回日本毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-15H01749
  • [Presentation] 多能性幹細胞を用いた大気汚染物質の毒性評価系の検討2017

    • Author(s)
      伊藤智彦,戸次加奈江,市瀬孝道,曽根秀子
    • Organizer
      日本薬学会
    • Place of Presentation
      仙台国際センター(宮城)
    • Data Source
      KAKENHI-PROJECT-16K12613
  • [Presentation] Phenotypic variation in the cloned pigs with heterozygous fibrillin-1 mutation.2017

    • Author(s)
      Kazuhiro Umeyama, Yoshikazu Arai, Kazuaki Nakano, Tooru Fukuda, Ikuma Umeki, Ayuko Uchikura, Yuri Kasai, Hitomi Matsunari, Masaki Nagaya, Masahito Watanabe, Jun Ohgane and Hiroshi Nagashima
    • Organizer
      4th World Congress of Reproductive Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H01749
  • [Presentation] 培養細胞を用いて環境汚染物質の毒性影響を探る2017

    • Author(s)
      伊藤智彦,曽根秀子
    • Organizer
      第15回環境研究シンポジウム
    • Data Source
      KAKENHI-PROJECT-16K12613
  • 1.  Sone Hideko (60280715)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 2.  桂 真理 (30436571)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  藤渕 航 (60273512)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  大鐘 潤 (50313078)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 5.  中尾 洋一 (60282696)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 6.  阿部 訓也 (40240915)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 7.  前川 文彦 (40382866)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  田中 厚資 (10896327)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MOCHIDATE Katsumi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  Nansai Hiroko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 11.  Kondo Masayo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  Suzuki Shinnosuke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  Otsuka Satoshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 14.  EITSUKA Takahiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  HIROSAWA Mitsuko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  吉田 稔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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