Yamada Hideomi 山田秀臣

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YAMADA Hideomi 山田秀臣

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Researcher Number	60396752
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2014: 東京大学, 医学部附属病院, 講師 2007 – 2013: 東京大学, 医学部附属病院, 助教 2008: 東京大学, 医学部・附属病院, 助教 2005 – 2006: 東京大学, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Kidney internal medicine / Neurology Except Principal Investigator Kidney internal medicine
Keywords	Principal Investigator NBC1 / 片頭痛 / NBCe1 / NBCe1変異 / 尿細管性アシドーシス / IRBIT / RTA / NBC1(NBCe1) / pRTA / NBC … More Except Principal Investigator … More H-ATPase / CLC5 / Dent病 / メタボリック症候群 / インスリン抵抗性 / 高血圧 / NBC1 / PTC124 / W516Xノックインマウス / 近位尿細管アシドーシス / NBCe1 / 近位尿細管性アシドーシス / cPLA2 / 腎近位尿細管 / PLA2 / ERK / アンジオテンシンII Less

Dent病発症の分子メカニズムと腎障害進行機序の解析
- Principal Investigator
  
  関常司
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
The significance of selective insulin resistance in kidney for hypertension and renal insufficiency.
- Principal Investigator
  
  SUZUKI Masashi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
The mechanism of regulation to occur the migrainePrincipal Investigator
- Principal Investigator
  
  YAMADA Hideomi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  The University of Tokyo
Development of new medication against proximal renal tubular acidosis
- Principal Investigator
  
  SEKI George
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Functional NBCe1 regulation by proteins'interactionPrincipal Investigator
- Principal Investigator
  
  YAMADA Hideomi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Role of cytosolic phospholipase A2 in intrarenalrenin-angiotensin system
- Principal Investigator
  
  SEKI George
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
ナトリウム重炭酸共輸送体を標的とした近位尿細管性アシドーシスの分子治療法の開発Principal Investigator
- Principal Investigator
  
  山田秀臣
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo

All 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book Other

[Book] Nephrology Frontier2013
- Author(s)
  山田　秀臣
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-23390229
[Book] 改定第８版内科学書2013
- Author(s)
  堀田　晶子、関　常司、山田　秀臣
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-25461242
[Book] 改定第８版内科学書2013
- Author(s)
  関　常司、堀田　晶子、山田　秀臣
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-25461242
[Book] 中外医学社2013
- Author(s)
  山田　秀臣
- Publisher
  スライド講義によるER型救急医療
- Data Source
  KAKENHI-PROJECT-23390229
[Book] カラー版内科学書2012
- Author(s)
  山田　秀臣
- Total Pages
  3
- Publisher
  西村書店
- Data Source
  KAKENHI-PROJECT-23390229
[Book] 内科2012
- Author(s)
  山田　秀臣
- Total Pages
  3
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-23390229
[Book] Gene Mutation2012
- Author(s)
  Seki G, Horita S, Suzuki M, Yamazaki O, Yamada H.
- Publisher
  Pathophysiological roles ofmutations in the electrogenic Na^+-HCO<3-> cotransporter NBCe1
- Data Source
  KAKENHI-PROJECT-21591051
[Book] 酸塩基平衡を調節するトランスポーター2011
- Author(s)
  山田秀臣、関常司
- Publisher
  BIO Clinica
- Data Source
  KAKENHI-PROJECT-21591051
[Book] 最新内科学2011
- Author(s)
  山田秀臣
- Total Pages
  3
- Publisher
  西村書店
- Data Source
  KAKENHI-PROJECT-20590971
[Book] 改訂第7版内科学書(近位尿細管機能異常)2009
- Author(s)
  堀田晶子、関常司、山田秀臣
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-20590971
[Book] 近位尿細管機能異常。改訂第7版内科学書2009
- Author(s)
  堀田晶子、関常司、山田秀臣
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-21591051
[Book] 近位尿細管性アシドーシスとアンモニア排泄。腎と透析2009
- Author(s)
  山田秀臣、関常司
- Publisher
  (東京医学社)
- Data Source
  KAKENHI-PROJECT-21591051
[Book] 腎と透析(Vol 67 近位尿細管性アシドーシスとアンモニア排泄)2009
- Author(s)
  山田秀臣、関常司
- Publisher
  東京医学社
- Data Source
  KAKENHI-PROJECT-20590971
[Book] 改訂第7版内科学書腎尿細管性アシドーシス2009
- Author(s)
  関常司、堀田晶子、山田秀臣
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-21591051
[Book] Annual Review腎臓NBCl:最近の進歩2009
- Author(s)
  山田秀臣、関常司
- Total Pages
  5
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20590971
[Book] 改訂第7版内科学書(腎尿細管性アシドーシス)2009
- Author(s)
  関常司、堀田晶子、山田秀臣, その他
- Total Pages
  520
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-21591051
[Book] 改訂第7版内科学書(腎尿細管性アシドーシス)2009
- Author(s)
  関常司, 堀田晶子, 山田秀臣
- Total Pages
  520
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-20590971
[Book] 改訂第7版内科学書(腎尿細管性アシドーシス)2009
- Author(s)
  関常司、堀田晶子、山田秀臣
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-20590971
[Journal Article] Angiotensin II dose-dependently stimulates human renal proximal tubule transport by the Nitric Oxide/ Guanosine 3', 5'-cyclic monophosphate pathway2014
- Author(s)
  Shirai A, Yamazaki O, Horita S, Nakamura M, Satoh N, Yamada H, Suzuki M, Kudo A, Kawakami H, Hofmann F, Nishiyama A, Kume H, Enomoto Y, Homma Y, Seki G
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-23390229
[Journal Article] Angiotensin II Dose-Dependently Stimulates Human Renal Proximal Tubule Transport by the Nitric Oxide/Guanosine 3',5'-Cyclic Monophosphate Pathway.2014
- Author(s)
  Shirai A, Yamazaki O, Horita S, Nakamura M, Satoh N, Yamada H, Suzuki M, Kudo A, Kawakami H, Hofmann F, Nishiyama A, Kume H, Enomoto Y, Homma Y, Seki G.
- Journal Title
  
  J Am Soc Nephrol.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390229
[Journal Article] Roles of renal proximal tubule transport in the pathogenesis of hypertension.2013
- Author(s)
  Horita S, Seki G, Yamada H, Suzuki M, Koike K, Fujita T.
- Journal Title
  
  Curr Hypertens Rev.
  
  Volume: 9 Pages: 148-55
- Data Source
  KAKENHI-PROJECT-23390229
[Journal Article] Mutation of the Mg^(2+) Transporter SLC41A1 Results in a Nephronophthisis-Like Phenotype.2013
- Author(s)
  Hurd TW, Otto EA, Mishima E, Gee HY, Inoue H, Inazu M, Yamada H, Halbritter J, Seki G, Konishi M, Zhou W, Yamane T, Murakami S, Caridi G, Ghiggeri G, Abe T, Hildebrandt F
- Journal Title
  
  J Am Soc Nephrol.
  
  Volume: 24 Issue: 6 Pages: 967-977
- DOI
  10.1681/asn.2012101034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590248, KAKENHI-PROJECT-23390033, KAKENHI-PROJECT-23390229, KAKENHI-PROJECT-24659062
[Journal Article] 尿細管性アシドーシスの分類とその機序2013
- Author(s)
  山田秀臣, 関常司
- Journal Title
  
  Nephrology Frontier
- Data Source
  KAKENHI-PROJECT-23390229
[Journal Article] Mutation of the renal Mg2+ transporter SLC41A1 in a nephronophthisis-like phenotype.2013
- Author(s)
  Hurd TW, Edgar Otto EA, Mishima E, Gee HY, Hana Inoue4, Inazu M, Yamada H, Halbritter J, Seki G, Konishi M, Zhou W, Yamane T, Murakami S, Caridi G, Ghiggeri G, Abe T, Hildeb F.
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591225
[Journal Article] The acid-base regulation by renal proximal tubule.2013
- Author(s)
  Horita S, Nakamura M, Yamada H, Suzuki M, Seki G.
- Journal Title
  
  Open Journal of Molecular and Integrative Physiology
  
  Volume: 3 Issue: 04 Pages: 186-193
- DOI
  10.4236/ojmip.2013.34024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461242
[Journal Article] Roles of renal proximal tubule transport in the pathogenesis of hypertension.2013
- Author(s)
  Horita S, Seki G, Yamada H, Suzuki M, Koike K, Fujita T.
- Journal Title
  
  Curr Hypertens Rev
  
  Volume: 9 Issue: 2 Pages: 148-55
- DOI
  10.2174/15734021113099990009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591225, KAKENHI-PROJECT-25461241
[Journal Article] Molecular mechanisms of renal and extrarenal manifestations caused by inactivation of the electrogenic Na(+)-HCO(3)(-) cotransporter NBCe1.2013
- Author(s)
  Seki G, Horita S, Suzuki M, Yamazaki O, Usui T, Nakamura M, Yamada H.
- Journal Title
  
  Front Physiol.
  
  Volume: 4 Pages: 270-270
- Data Source
  KAKENHI-PROJECT-23390229
[Journal Article] Bartter症候群とGitelman症候群2012
- Author(s)
  山田秀臣
- Journal Title
  
  カラー版内科学書
  
  Pages: 1528-31
- Data Source
  KAKENHI-PROJECT-23390229
[Journal Article] ファンコニ症候群2012
- Author(s)
  山田秀臣
- Journal Title
  
  内科
  
  Volume: Vol109, No6 Pages: 1381-1383
- Data Source
  KAKENHI-PROJECT-23390229
[Journal Article] Pathophysiological roles of mutations in the electrogenic Na+-HCO3- cotransporter NBCe12012
- Author(s)
  Seki G, Horita S, Suzuki M, Yamazaki O, Yamada H
- Journal Title
  
  Mutations in Human Genetic Disease
  
  Volume: 167-180
- Data Source
  KAKENHI-PROJECT-23390229
[Journal Article] リドル症候群2012
- Author(s)
  山田秀臣
- Journal Title
  
  内科
  
  Volume: Vol109, No6 Pages: 1386-1387
- Data Source
  KAKENHI-PROJECT-23390229
[Journal Article] Functional Roles of Electrogenic Sodium Bicarbonate Cotransporter NBCe1 in Ocular Tissues.2012
- Author(s)
  Suzuki M, Seki G, Yamada H, Horita S, Fujita T.
- Journal Title
  
  Open Ophthalmol J.
  
  Volume: 6 Issue: 1 Pages: 36-41
- DOI
  10.2174/1874364101206010036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790932, KAKENHI-PROJECT-24591225
[Journal Article] Role of renal proximal tubule transport in thiazolidinediones -induced volume expansion2012
- Author(s)
  Seki G, Endo Y, Suzuki M, Yamada H, Horita S, Fujita T
- Journal Title
  
  World Journal of Nephrology 6
  
  Volume: 1(5) Pages: 146-150
- Data Source
  KAKENHI-PROJECT-23390229
[Journal Article] Re-lowering of serum Na for osmotic demyelinating syndrome.2012
- Author(s)
  Yamada H, Takano K, Ayuzawa N, Seki G and Fujita T.
- Journal Title
  
  Case Reports in Neurological Medicine
  
  Volume: 2012 Pages: 704639-704639
- DOI
  10.1155/2012/704639
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591348, KAKENHI-PROJECT-24591225
[Journal Article] Functional roles of electrogenic sodium bicarbonate cotransporter NBCe1 in ocular tissues2012
- Author(s)
  Suzuki M, Seki G, Yamada H, Horita S, Fujita T
- Journal Title
  
  The Open Ophthalmology Journal 6
  
  Pages: 36-41
- Data Source
  KAKENHI-PROJECT-23390229
[Journal Article] Thiazolidinediones enhance sodium-coupled bicarbonate absorption from renal proximal tubules via PPAR・-dependent non-genomic signaling2011
- Author(s)
  Endo Y, Suzuki M, Yamada H, Horita S, Kunimi M, Yamazaki O, Shirai A, Nakamura M, Iso-O N, Li Y, Hara M, Tsukamoto K, Moriyama N, Kudo A, Kawakami H, Yamauchi T, Kubota N, Kadowaki T, Kume H, Enomoto Y, Homma Y, Seki G, Fujita T
- Journal Title
  
  Cell Metab
  
  Volume: 13 Pages: 550-561
- Data Source
  KAKENHI-PROJECT-23390229
[Journal Article] Lin S : Physiological and pathophysiological roles of the electrogenic Na^+-HCO_<3-> cotransporter NBCe12011
- Author(s)
  Seki G, Yamada H, Horita S, Suzuki M, Yamazaki O, Van Paesschen W, Yang S
- Journal Title
  
  Open Journal of Molecular and Integrative Physiology
  
  Volume: 1 Pages: 9-16
- Data Source
  KAKENHI-PROJECT-21591051
[Journal Article] Physiological and pathophysiological roles of the electrogenic Na+-HCO3- cotransporter NBCe12011
- Author(s)
  Seki G, Yamada H, Horita S, Suzuki M, Yamazaki O, Van Paesschen W, Yang S, Lin S
- Journal Title
  
  Open Journal of Molecular and Integrative Physiology
  
  Volume: 1 Pages: 9-16
- Data Source
  KAKENHI-PROJECT-23390229
[Journal Article] Functional characterization of nonsynonymous single nucleotide polymorphisms in the electrogenic Na^+-HCO_<3-> cotransporter NBCe1A2011
- Author(s)
  Yamazaki O, Yamada H, Suzuki M, Horita S, Shirai A, Nakamura M, SekiG, Fujita T
- Journal Title
  
  Pflugers Arch
  
  Volume: 461 Pages: 249-259
- Data Source
  KAKENHI-PROJECT-21591051
[Journal Article] Severe Metabolic Acidosis Causes Early Lethality in NBC1 W516X Knock-in Mice as a Model of Human Isolated Proximal Renal Tubular Acidosis2011
- Author(s)
  Lo Y, BS, Yang S, Seki G, Yamada H, Horita S, Yamazaki O, Fujita T, MD, Usui T, Tsai J, Yu I, PhD6, Lin S, Lin S
- Journal Title
  
  Kidney Int
  
  Volume: 79 Pages: 730-741
- Data Source
  KAKENHI-PROJECT-23390229
[Journal Article] Functional characterization of non-synonymous single nucleotide polymorphisms in the electrogenic Na^+-HCO_3^- cotransporter NBCe1A.2011
- Author(s)
  Yamazaki O, Yamada H, Suzuki M, Horita S, Shirai A, Nakamura M, Seki G, Fujita T
- Journal Title
  
  Pflugers Arch 461
  
  Pages: 249-259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590971
[Journal Article] Severe Metabolic Acidosis Causes Early Lethality in NBC1 W516X Knock-in Mice as a Model of Human Isolated Proximal Renal Tubular Acidosis2011
- Author(s)
  Lo Y, BS, Yang S, Seki G, Yamada H, Horita S, Yamazaki O, Fujita T, MD, Usui T, Tsai J, Yu I, PhD, Lin S, Lin S
- Journal Title
  
  Kidney Int
  
  Volume: 79 Pages: 730-741
- Data Source
  KAKENHI-PROJECT-21591051
[Journal Article] Severe Metabolic Acidosis Causes Early Lethality in NBC1 W516X Knock-in Mice as a Model of Human Isolated Proximal Renal Tubular Acidosis.2011
- Author(s)
  Lo Y, BS, Yang S, Seki G, Yamada H, Horita S, et al.
- Journal Title
  
  Kidney Int
  
  Volume: 79 Pages: 730-741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591051
[Journal Article] Severe Metabolic Acidosis Causes Early Lethality in NBC1 W516X Knock-in Mice as a Model of Human Isolated Proximal Renal Tubular Acidosis.2011
- Author(s)
  Lo Y, BS, Yang S, Seki G, Yamada H, Horita S, Yamazaki O, Fujita T, MD, Usui T, Tsai J, Yu I, PhD6, Lin S, Lin S
- Journal Title
  
  Kidney Int 9
  
  Pages: 730-741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590971
[Journal Article] Functional role of a putative carbonic anhydrase II-binding domain in the electrogenic Na^+-HCO_3^- cotransporter NBCe1 expressed in Xenopus oocytes2011
- Author(s)
  Yamada H, Horita S, Suzuki M, Fujita F, Seki G
- Journal Title
  
  Channels
  
  Volume: 5 Issue: 2 Pages: 1-4
- DOI
  10.4161/chan.5.2.14341
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591051, KAKENHI-PROJECT-23390229
[Journal Article] Functional characterization of non -synonymous single nucleotide poly -morphisms in the electrogenic Na+-HCO3- cotransporter NBCe1A2011
- Author(s)
  Yamazaki O, Yamada H, Suzuki M, Horita S, Shirai A, Nakamura M, Seki G, Fujita T
- Journal Title
  
  Pflugers Arch
  
  Volume: 461 Pages: 249-259
- Data Source
  KAKENHI-PROJECT-23390229
[Journal Article] Functional role of a putative carbonic anhydrase II-binding domain in the electrogenic Na^+-HCO_3^- cotransporter NBCe1 expressed in Xenopus oocytes.2011
- Author(s)
  Yamada H, Horita S, Suzuki M, Fujita F, Seki G
- Journal Title
  
  Channels 5:2
  
  Pages: 1-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590971
[Journal Article] Functional role of a putative carbonic anhydrase II-binding domain in the electrogenic Na+-HCO3- cotransporter NBCe1 expressed in Xenopus oocytes2011
- Author(s)
  Yamada H, Horita S, Suzuki M, Fujita F, Seki G
- Journal Title
  
  Channels
  
  Volume: 5:2 Pages: 1-4
- Data Source
  KAKENHI-PROJECT-23390229
[Journal Article] 酸塩基平衡を調節するトランスポーター2011
- Author(s)
  山田秀臣, 関常司
- Journal Title
  
  BIO Clinica
  
  Volume: Vol26 No11 Pages: 34-40
- Data Source
  KAKENHI-PROJECT-23390229
[Journal Article] Thiazolidinediones enhance sodium-coupled bicarbonate absorption from renal proximal tubules via PPARγ-dependent non-genomic signaling2011
- Author(s)
  Endo Y, Suzuki M, Yamada H, Horita S, Kunimi M, Yamazaki O, Shirai A, Nakamura M, Iso-O N, Li Y, Hara M, Tsukamoto K, Moriyama N, Kudo A, Kawakami H, Yamauchi T, Kubota N, Kadowaki T, Kume H, Enomoto Y, Homma Y, Seki G, Fujita T
- Journal Title
  
  Cell Metab
  
  Volume: 13 Pages: 550-561
- Data Source
  KAKENHI-PROJECT-21591051
[Journal Article] Functional role of a putative carbonic anhydrase II-binding domain in the electrogenic Na^+-HCO_<3-> cotransporter NBCe1 expressed in Xenopus oocytes2011
- Author(s)
  Yamada H, Horita S, Suzuki M, FujitaF, Seki G
- Journal Title
  
  Channels
  
  Volume: 5 : 2 Pages: 1-4
- Data Source
  KAKENHI-PROJECT-21591051
[Journal Article] Insulin resistance, obesity, hypertension and renal sodium transport2011
- Author(s)
  Horita S, Seki G, Yamada H, Suzuki M, Koike K, Fujita T
- Journal Title
  
  Int J Hypertension
  
  Volume: 2011 Pages: 391762-391762
- DOI
  10.4061/2011/391762
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591051, KAKENHI-PROJECT-23390229, KAKENHI-PROJECT-23790932
[Journal Article] Metabolic syndrome and insulin signaling in kidney2011
- Author(s)
  Horita S, Seki G, Yamada H, Suzuki M, Nakamura M, Fujita T.
- Journal Title
  
  Endocrinol Metabol Syndrome
  
  Volume: S1 : 005 Issue: S1 Pages: 5-5
- DOI
  10.4172/2161-1017.s1-005
- Data Source
  KAKENHI-PROJECT-21591051, KAKENHI-PROJECT-23390229
[Journal Article] Defective membrane expression of the Na+-HCO3-cotransporter NBCe1 is associated with familial migraine.2010
- Author(s)
  Suzuki M, Stalmans I, Horita S, Yamada H, Seki G, et al
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 107 Pages: 15963-15968
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591051
[Journal Article] Human sodium-phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate.2010
- Author(s)
  Jutabha P, Anzai N, Kitamura K, Taniguchi A, Kaneko S, Yan K, Yamada H, Shimada H, Kimura T, Katada T, Fukutomi T, Tomita K, Urano W, Yamanaka H, Seki G, Fujita T, Moriyama Y, Yamada A, Uchida S, Michael F.Wempe MF, Endou H, Sakurai H
- Journal Title
  
  J Biol Chem 285
  
  Pages: 35123-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590971
[Journal Article] Defective membrane expression of the Na^+-HCO_3^- cotransporter NBCe1 is associated with familial migraine.2010
- Author(s)
  Suzuki M, Paesschen WV, Stalmans I, Horita S, Yamada H, Bergmans BA, Legius E, Riant F, Jonghe PD, Li Y, Sekine T, Igarashi T, Fujimoto I, Mikoshiba M, Shimadzu M, Shiohara M, Braverman N, Al-Gazali L, Fujita Y, Seki G
- Journal Title
  
  Proc Natl Acad Sci U S A 107
  
  Pages: 15963-15968
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590971
[Journal Article] Defective membrane expression of the Na^+-HCO<3-> cotransporter NBCe1 is associated with familial migraine2010
- Author(s)
  Suzuki M, Paesschen WV, Stalmans I, Horita S, Yamada H, Bergmans BA, Legius E, Riant F, Jonghe PD, Li Y, Sekine T, Igarashi T, Fujimoto I, KMikoshiba M, Shimadzu M, Shiohara M, Braverman N, Al-Gazali L, Fujita Y, Seki G
- Journal Title
  
  Proc Natl AcadSci USA
  
  Volume: 107 Pages: 15963-15968
- Data Source
  KAKENHI-PROJECT-21591051
[Journal Article] Roles of MEK/ERK pathway in vascular and renal tubular actions of angiotensin II.2009
- Author(s)
  Seki G, Yamada H, Li Y, Horita S, Ishizaka N, Koike K, Fujita T
- Journal Title
  
  Vascular Disease Prevention 6
  
  Pages: 154-159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590971
[Journal Article] 近位尿細管性アシドーシスとアンモニア排泄2009
- Author(s)
  山田秀臣, 関常司
- Journal Title
  
  腎と透析 67
  
  Pages: 53-55
- Data Source
  KAKENHI-PROJECT-20590971
[Journal Article] Roles ofMEK/ERK pathway in vascular and renaltubular actions of angiotensin II2009
- Author(s)
  Seki G, Yamada H, Li Y, Horita S, Ishizaka N, Koike K and Fujita T
- Journal Title
  
  Vascular Disease Prevention 6
  
  Pages: 154-159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590934
[Journal Article] Roles of MEK/ERK pathway in vascular and renal tubular actions of angiotensin II2009
- Author(s)
  Seki G, Yamada H, Li Y, Horita S, Ishizaka N, Koike K, Fujita T
- Journal Title
  
  Vascular Disease Prevention 6
  
  Pages: 154-159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590971
[Journal Article] Roles of MEK/ERK pathway in vascular and renal tubular actions of angiotensin II.2009
- Author(s)
  Seki G, Yamada H, Li Y, Horita S, Ishizaka N, Koike K, Fujita T
- Journal Title
  
  Vascular Disease Prevention 6
  
  Pages: 154-159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591051
[Journal Article] Roles of MEK/ERK pathway in vascular and renal tubular actions of angiotensin II2009
- Author(s)
  Seki G, Yamada H, Li Y, Horita S, Ishizaka N, Koike K and Fujita T
- Journal Title
  
  Vascular Disease Prevention
  
  Volume: 6 Pages: 154-159
- Data Source
  KAKENHI-PROJECT-21591051
[Journal Article] 近位尿細管性アシドーシスとアンモニア排泄2009
- Author(s)
  山田秀臣、関常司
- Journal Title
  
  腎と透析 67
  
  Pages: 53-55
- Data Source
  KAKENHI-PROJECT-21591051
[Journal Article] Functionalanalysis of a novel missense NBC1mutation and of other mutations causingproximal renal tubular acidosis2008
- Author(s)
  Suzuki M, Vaisbich M, Yamada H,Horita S, Li Y, Sekine T, Moriyama N,Igarashi T, Endo Y, Cardoso T, de Sa L,Koch H, Seki G, Fujita, T
- Journal Title
  
  Pflugers Arch 455
  
  Pages: 583-593
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590934
[Journal Article] Arachidonic acid metabolites inhibit the stimulatory effect of Angiotensin II in renal tubules.2008
- Author(s)
  Li Y, H Yamada et al
- Journal Title
  
  Hypertens Res. 12
  
  Pages: 2155-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590971
[Journal Article] The Roles of Abnormal Renal Sodium Handling in Hypertension Associated with Metabolic Syndrome.2008
- Author(s)
  Seki G, Yamada H, Li Y, Horita S, Suzuki M, Fujita T
- Journal Title
  
  Current Hypertension Reviews 4
  
  Pages: 197-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590971
[Journal Article] The Roles ofAbnormal Renal Sodium Handling inHypertension Associated with MetabolicSyndrome2008
- Author(s)
  Seki G, Yamada H, Li Y, Horita S, Suzuki M and Fujita T
- Journal Title
  
  Current Hypertension Reviews 4
  
  Pages: 197-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590934
[Journal Article] Arachidonic acid metabolites inhibit the stimulatory effect of angiotensin II in renal proximal tubules.2008
- Author(s)
  Li Y, Yamada H, Kita Y, Suzuki M, Endo Y, Horita S, Yamazaki O, Shimizu T, Seki G, Fujita T
- Journal Title
  
  Hypertension Res 31
  
  Pages: 2155-2164
- NAID
  10024828609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590971
[Journal Article] Activation and Inactivation Mechanisms of Na-HCO3 Cotransporter NBC12008
- Author(s)
  Seki G, Yamada H, Horita S, Suzuki M, Sekine T, Igarashi T and Fujita T
- Journal Title
  
  J Epithelial Biology and Pharmacology 1
  
  Pages: 35-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590934
[Journal Article] Functional analysis of a novel missense NBC1 mutation and of other mutations causing proximal renal tubular acidosis.2008
- Author(s)
  Suzuki M, Vaisbich M, Yamada H, Horita S, Li Y, Sekine T, Moriyama N, Igarashi T, Endo Y, Cardoso T, de Sa L, Koch H, Seki G, Fujita, T
- Journal Title
  
  Pflugers Arch 455
  
  Pages: 583-593
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590971
[Journal Article] Activation and Inactivation Mechanisms of Na-HCO3 Cotransporter NBC1.2008
- Author(s)
  Seki G, Yamada H, Horita S, Suzuki M, Sekine T, Igarashi T, Fujita T
- Journal Title
  
  J Epithelial Biology and Pharmacology 1
  
  Pages: 35-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590971
[Journal Article] Roles of ERK and cPLA2in the angiotensin II-mediated biphasicregulation of Na + - HCO3 - transport2008
- Author(s)
  Li Y, Yamada H, Kita Y, Kunimi M, Horita S, Suzuki M, Endo Y, Shimizu T,Seki G, Fujita T
- Journal Title
  
  J Am Soc Nephrol 19
  
  Pages: 252-259
- Data Source
  KAKENHI-PROJECT-19590934
[Journal Article] Arachidonic acid metabolitesinhibit the stimulatory effect of angiotensin II in renal proximal tubules2008
- Author(s)
  Li Y, Yamada H, Kita Y, Suzuki M, EndoY, Horita S, Yamazaki O, Shimizu T, SekiG, Fujita T
- Journal Title
  
  Hypertension Res 31
  
  Pages: 2155-2164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590934
[Journal Article] Roles of ERK and cPLA2 in the angiotensin II-mediated biphasic regulation of Na^+-HCO_3^- transport.2008
- Author(s)
  Li Y, Yamada H, Kita Y, Kunimi M, Horita S, Suzuki M, Endo Y, Shimizu T, Seki G, Fujita T
- Journal Title
  
  J Am Soc Nephrol 19
  
  Pages: 252-259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590971
[Journal Article] Functional analysis of a novel missense NBC1 mutation and of other mutations causing proximal renal tubular acidosis.2007
- Author(s)
  Suzuki M, Vaisbich H M, Yamada H, Horita S, Li Y, Sekine T, Moriyama N, Seki G et al.
- Journal Title
  
  Pflugers Archiv (in press)
- Data Source
  KAKENHI-PROJECT-17790546
[Journal Article] IRBIT, an inositol 1,4,5-trisphosphate receptor-binding protein, specifically binds to and activates pancreas-type Na+/HCO3-cotransporter 1 (pNBC1).2006
- Author(s)
  Shirakabe K, Priori G, Yamada H, Horita S, Seki G, Mikoshiba K et al.
- Journal Title
  
  Proc Natl Acad Sci U S A. 103
  
  Pages: 9542-9547
- Data Source
  KAKENHI-PROJECT-17790546
[Journal Article] Functional analysis of NBC1 associated with proximal renal tubular acidosis and ocular abnormalities.2005
- Author(s)
  Horita S, Yamada H, Inatomi J, Moriyama N, Seki G et al.
- Journal Title
  
  J Am Soc Nephrol 16
  
  Pages: 2270-2278
- Data Source
  KAKENHI-PROJECT-17790546
[Journal Article] Roles of insulin receptor substrates in insulin-induced stimulation of renal proximal bicarbonate absorption.2005
- Author(s)
  Zheng Y, Yamada H, Sakamoto K, Horita S, Seki G et al.
- Journal Title
  
  J Am Soc Nephrol 16
  
  Pages: 2288-2295
- Data Source
  KAKENHI-PROJECT-17790546
[Journal Article] Roles of insulin receptor substrates in insulin-induce stimulation of renal proximal bicarbonate absorption.2005
- Author(s)
  Zheng Y, Yamada H, Sakamoto K, Horita S, Seki G et al.
- Journal Title
  
  J Am Soc Nephrol
  
  Pages: 2288-2295
- Data Source
  KAKENHI-PROJECT-17790546
[Journal Article] Localization of NBC1 variants in rat kidney.
- Author(s)
  Endo Y, Yamazaki S, Moriyama N, Li Y, Arizumi T, Yamada H, Seki G et al.
- Journal Title
  
  Nephron (In Press)
- Data Source
  KAKENHI-PROJECT-17790546
[Journal Article] 酸塩基平衡について
- Author(s)
  山田秀臣
- Journal Title
  
  スライド講義によるER 型救急医療:ER Grand Rounds(中外医学社)
  
  Volume: (仮題)(仮称)(予定)
- Data Source
  KAKENHI-PROJECT-23390229
[Presentation] 重炭酸輸送体の創薬可能性について2014
- Author(s)
  山田秀臣
- Organizer
  2013年度生理学会プレワークショップ
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-23390229
[Presentation] インスリンはPI3キナーゼ/IRS2/Akt2を介して近位尿細管Na再吸収を亢進させる2014
- Author(s)
  中村　元信、白井　雅弓、山田　秀臣、堀田　晶子、鈴木　正志、佐藤　信彦、濱崎　敬文、野入　英世、関　常司
- Organizer
  第57回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-07-06
- Data Source
  KAKENHI-PROJECT-24591225
[Presentation] CLC5の2Cl/H交換輸送はH-ATPase最大活性化に必要である2014
- Author(s)
  佐藤　信彦、山田　秀臣、山崎　修、堀田　晶子、鈴木　正志、芦田　明、山本　大助、郭義胤、関根　孝司、関　常司
- Organizer
  日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-07-06
- Data Source
  KAKENHI-PROJECT-25461242
[Presentation] 2Cl/H exchange function of CLC-5 is required for the H-ATPase-mediated maximal endosome acidification2014
- Author(s)
  Nobuhiko Sato, Hideomi Yamada, Osamu Yamazaki, Shoko Horita, Masashi Suzuki, Motonobu Nakamura, Yoshitsugu Kaku, Daisuke Yamamoto, Akira Ashida, Takashi Sekine, George Sek
- Organizer
  ASN Annual Meeting
- Place of Presentation
  フィラデルフィア
- Year and Date
  2014-11-14
- Data Source
  KAKENHI-PROJECT-25461242
[Presentation] インスリン抵抗性における腎近位尿細管インスリンシグナル伝達保持機構2014
- Author(s)
  中村　元信、白井　雅弓、山田　秀臣、堀田　晶子、鈴木　正志、佐藤　信彦、本間　之夫、久米　春喜、関　常司
- Organizer
  第57回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-07-06
- Data Source
  KAKENHI-PROJECT-24591225
[Presentation] インスリン抵抗性におけるインスリンの近位尿細管作用機序2013
- Author(s)
  中村元信、山崎修、白井雅弓、山田秀臣、堀田晶子、鈴木正志、榎本裕、久米春喜、本間之夫、関常司
- Organizer
  第56回日本腎臓学会学術総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591225
[Presentation] Loss of 2Cl/H exchange function of CLC-5 causes Dent’s disease2013
- Author(s)
  Nobuhiko Sato, Hideomi Yamada, Osamu Yamazaki, Shoko Horita, Masashi Suzuki, Motonobu Nakamura, Yoshitsugu Kaku, Daisuke Yamamoto, Akira Ashida, Takashi Sekine, George Seki
- Organizer
  Annual Meeting of American Society of Nephrology
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-25461242
[Presentation] CLC5の2Cl/H交換輸送機能の喪失はDent病を生じる2013
- Author(s)
  佐藤　信彦、山田　秀臣、山崎　修、堀田　晶子、鈴木　正志、芦田　明、山本　大助、郭義胤、関根　孝司、関　常司
- Organizer
  第56回日本腎臓学会学術総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25461242
[Presentation] NO/sGC/cGMP/ERK pathway mediates a unique dose-dependent stimulation of human proximal transport by angiotensin II.2012
- Author(s)
  Ayumi Shirai, Osamu Yamazaki, Motonobu Nakamura, Hideomi Yamada, Masashi Suzuki, Shoko Horita, Yukio Homma, George Seki
- Organizer
  Annual Meeting of American Society of Nephrology
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24591225
[Presentation] インスリン抵抗性におけるインスリンの近位尿細管輸送亢進作用機序2012
- Author(s)
  中村元信, 山崎修, 白井雅弓, 山田秀臣, 堀田晶子, 鈴木正志, 榎本裕, 久米春喜, 本間之夫, 関常司, 藤田敏郎
- Organizer
  第55回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2012-06-02
- Data Source
  KAKENHI-PROJECT-23390229
[Presentation] Stimulatory effect of insulin on renal proximal Na transport is preserved in insulin resistance.2012
- Author(s)
  Motonobu Nakamura, Ayumi Shirai, Osamu Yamazaki, Hideomi Yamada, Masashi Suzuki, Shoko Horita, Yukio Homma, George Seki
- Organizer
  Annual Meeting of American Society of Nephrology
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24591225
[Presentation] 上皮輸送と細胞内外pH調節機構におけるNa-HCO3共輸送体NBCe1の意義2012
- Author(s)
  山崎修, 山田秀臣, 鈴木正志, 堀田晶子, 関常司
- Organizer
  2012年度生理研研究会「粘膜防御における上皮膜輸送の役割とその破綻による疾病発症メカニズム」
- Place of Presentation
  岡崎
- Data Source
  KAKENHI-PROJECT-23390229
[Presentation] アンジオテンシン(Ang)IIのヒト近位尿細管特異的作用機序2012
- Author(s)
  白井雅弓, 山崎修, 中村元信, 山田秀臣, 堀田晶子, 鈴木正志, 榎本裕, 久米春喜, 本間之夫, Franz Hofmann, 関常司, 藤田敏郎
- Organizer
  第55回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2012-06-01
- Data Source
  KAKENHI-PROJECT-23390229
[Presentation] インスリンの近位尿細管輸送亢進作用はインスリン抵抗性でも保たれる2011
- Author(s)
  中村元信, 山崎修, 白井雅弓, 山田秀臣, 堀田晶子, 鈴木正志, 榎本裕, 久米春喜, 本間之夫, 関常司, 藤田敏郎
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-23390229
[Presentation] アンジオテンシンIIのヒト近位尿細管作用におけるNO/sGC/cGMP経路の意義2011
- Author(s)
  白井雅弓, 山崎修, 中村元信, 山田秀臣, 堀田晶子, 鈴木正志, 榎本裕, 久米春喜, 本間之夫, 関常司, 藤田敏郎
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2011-06-15
- Data Source
  KAKENHI-PROJECT-23390229
[Presentation] Na-HCO3トランスポーターNBCe1変異体ノックインマウスと尿細管性アシドーシス2011
- Author(s)
  関常司, Sung-Sen Yang, 山崎修, 石黒洋, 山田秀臣, Shih-Hua Lin
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2011-06-15
- Data Source
  KAKENHI-PROJECT-23390229
[Presentation] 近位尿細管輸送の特性と調節機構2011
- Author(s)
  関常司、山田秀臣、堀田晶子
- Organizer
  第88回日本生理学会大会
- Place of Presentation
  横浜
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21591051
[Presentation] NBCe1のL522P変異体はドミナントネガティブ効果を有する2011
- Author(s)
  山崎修, 山田秀臣, 鈴木正志, 堀田晶子, 遠藤陽子, 白井雅弓, 中村元信, 関常司, 藤田敏郎
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-23390229
[Presentation] The cytosolic mutant L522P of NBCe1 has a dominant negative effect2011
- Author(s)
  Yamazaki O, Yamada H, Suzuki M, Horita S, Nakamura M, Seki G, Fujita T
- Organizer
  Annual Meeting of American Society of Nephrology
- Place of Presentation
  フィラデルフィア(米国)(招待講演)
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-23390229
[Presentation] The cytosolic mutant L522P of NBCe1 has a dominant negative effect2011
- Author(s)
  Yamazaki O, Yamada H, Suzuki M, Horita S, Nakamura M, Seki G, Fujita T
- Organizer
  Annual Meeting of American Society of Nephrology
- Place of Presentation
  フィラデルフィア(米国)(招待講演)
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-21591051
[Presentation] NBCe1のL522P変異体はドミナントネガティブ効果を有する2011
- Author(s)
  山崎修、山田秀臣、鈴木正志、堀田晶子、遠藤陽子、白井雅弓、中村元信、関常司、藤田敏郎
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-21591051
[Presentation] Na-HCO3_トランスポーターNBCe1変異体ノックインマウスと尿細管性アシドーシス2011
- Author(s)
  関常司、Sung-Sen Yang,山崎修、石黒洋、山田秀臣、Shih-Hua Lin
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2011-06-15
- Data Source
  KAKENHI-PROJECT-21591051
[Presentation] NBC1W516Xノックインマウスを用いたNBC1の生理機能解析2010
- Author(s)
  山崎修、Lo Yi-Fen、白井雅弓、山本明子、Song Ying、石黒洋、Yang Sung-Sun、Lin Shih-Hua、堀田晶子、山田秀臣、関常司,藤田敏郎
- Organizer
  第5回トランスポーター研究会年会
- Place of Presentation
  東京
- Year and Date
  2010-07-10
- Data Source
  KAKENHI-PROJECT-21591051
[Presentation] NBC1のSNP変異K558Rは機能低下を呈する2010
- Author(s)
  山崎修、山田秀臣、堀田晶子、鈴木正志、関常司、藤田敏郎
- Organizer
  第5回トランスポーター研究会年会
- Place of Presentation
  東京
- Year and Date
  2010-07-10
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] NBC1W516XノックインマウスによるNBC1生理的機能の解析2010
- Author(s)
  山崎修、Lo Yi-Fen、白井雅弓、山本明子、Song Ying、石黒洋、Yang Sung-Sun、Lin Shih-Hua、堀田晶子、山田秀臣、関常司、藤田敏郎
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] インスリン抵抗性におけるインスリンの近位尿細管作用2010
- Author(s)
  堀田晶子、山崎修、山田秀臣、鈴木正志、遠藤陽子、関常司、藤田敏郎
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] Defective membrane expression of Na-HCO3 cotransporter NBCe1 is associated with migraine2010
- Author(s)
  Suzuki M, Seki G, Horita S, Yamada H, Igarashi T, Fujita T
- Organizer
  Annual Meeting of American Society of Nephrology
- Place of Presentation
  Denver, USA
- Data Source
  KAKENHI-PROJECT-21591051
[Presentation] NBC1のSNP変異K558Rは機能低下型変異である2010
- Author(s)
  山崎修、山田秀臣、堀田晶子、鈴木正志、関常司、藤田敏郎
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-21591051
[Presentation] NBC1W516XノックインマウスによるNBC1生理的機能の解析2010
- Author(s)
  山崎修、Lo Yi-Fen、白井雅弓、山本明子、Song Ying、石黒洋、Yang Sung-Sun、Lin Shih-Hua、堀田晶子、山田秀臣、関常司、藤田敏郎
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-21591051
[Presentation] Defective membrane expression of Na-HCO3 cotransporter NBCe1 is associated with migraine.2010
- Author(s)
  Suzuki M, Seki G, Horita S, Yamada H, Igarashi T, Fujita T
- Organizer
  Annual Meeting of American Society of Nephrology.
- Place of Presentation
  Denver, USA
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] NBC1のSNP変異K558Rは機能低下型変異である2010
- Author(s)
  山崎修、山田秀臣、堀田晶子、鈴木正志、関常司、藤田敏郎
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] Functional analysis of SNP mutations leading to single amino acid substitution in NBCe1.2010
- Author(s)
  Yamazaki O, Yamada H, Suzuki M, Horita S, Shirai A, Seki G, Fujita T
- Organizer
  Annual Meeting of American Society of Nephrology.
- Place of Presentation
  Denver, USA
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] NBC1 W516Xノックインマウスを用いたNBC1の生理機能解析2010
- Author(s)
  山崎修、Lo Yi-Fen、白井雅弓、山本明子、Song Ying、石黒洋、Yang Sung-Sun、Lin Shih-Hua、堀田晶子、山田秀臣、関常司,藤田敏郎
- Organizer
  第5回トランスポーター研究会年会
- Place of Presentation
  東京
- Year and Date
  2010-07-10
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] アンジオテンシンIIはヒト近位尿細管NBC1活性を濃度依存的に亢進させる2010
- Author(s)
  白井雅弓、山崎修、山田秀臣、堀田晶子、鈴木正志、榎本裕、久米春喜、本間之夫、関常司、藤田敏郎
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] NBC1 mutations showing defective plasma membrane expression cause pH dysregulation in astrocytes and are associated with migraine2009
- Author(s)
  Suzuki M, Horita S, Van Paesschen W, Yamada H, Bergmans B, T Sekine T, Igarashi T, Seki G, Fujita T
- Organizer
  ISN Frontier
- Place of Presentation
  Florence, Italy
- Data Source
  KAKENHI-PROJECT-21591051
[Presentation] 近位尿細管性アシドーシス研究の現状と課題2009
- Author(s)
  関常司、堀田晶子、鈴木正志、山田秀臣
- Organizer
  第44回日本小児腎臓学会学術集会
- Place of Presentation
  東京
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation]2009
- Author(s)
  山田秀臣、永吉旭土、水谷顕洋、安東英明、御子柴克彦、堀田晶子、鈴木正志、関常司、藤田敏郎
- Organizer
  第52回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-06-03
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] Identification of human brain type NBCl and its regulation by IRBIT2009
- Author(s)
  山田秀臣、永吉旭土、水谷顕洋、安東英明、御子柴克彦、関常司、藤田敏郎
- Organizer
  トランスポーター研究会、九州部会
- Place of Presentation
  鹿児島大学
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] Functional comparison and mutational analysis of NBCl variants expressed in Xenopus Oocytes with IRBIT2009
- Author(s)
  Hideomi Yamada, Shoko Horita, Masashi Suzuki, George Seki
- Organizer
  国際腎臓学会
- Place of Presentation
  イタリア、ミラノ
- Year and Date
  2009-05-23
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] NBC1 mutations showing defective plasma membrane expression cause pH dysregulation in astrocytes and are associated with migraine.2009
- Author(s)
  Suzuki M, Horita S, Van Paesschen W, Yamada H, Bergmans B, T Sekine T, Igarashi T, Seki G, Fujita T
- Organizer
  ISN Frontier 2009
- Place of Presentation
  Florence, Italy
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] Functional comparison of NBC1 variants expressed in Xenopus oocytes.2009
- Author(s)
  Yamada H, Horita S, Suzuki M, Seki G
- Organizer
  World Congress of Nephrology 2009.
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] NBC1のSNP変異体の解析2009
- Author(s)
  山崎修、山田秀臣、堀田晶子、鈴木正志、関常司、藤田敏郎
- Organizer
  第52回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] Identification of human brain type NBCl and its regulation by IRBIT2009
- Author(s)
  Hideomi Yamada, Shoko Horita, Masashi Suzuki, George Seki
- Organizer
  国際腎臓学会, ISN forefronts symposium
- Place of Presentation
  イタリア、フィレンツェ
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] 近位尿細管性アシドーシス研究の現状と課題2009
- Author(s)
  関常司、堀田晶子、鈴木正志、山田秀臣
- Organizer
  第44回日本小児腎臓学会学術集会
- Place of Presentation
  東京
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-21591051
[Presentation] NBC1の病態生理学的意義とヴァリアント特異的調節機構2009
- Author(s)
  関常司、山田秀臣、堀田晶子、鈴木正志、藤田敏郎
- Organizer
  第52回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] ヒト脳型NBClはIRBITと機能的複合体を形成する2009
- Author(s)
  山田秀臣、永吉旭土、重本隆一、水谷顕洋、黒田有希子、安東英明、御子柴克彦、関常司、藤田敏郎
- Organizer
  日本腎臓学会
- Place of Presentation
  横浜
- Year and Date
  2009-06-03
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] Identification of human brain type NBC1 and its regulation by IRBIT.2009
- Author(s)
  Yamada H, Nagayoshi A, Mizutani A, Ando H, Mikoshiba K, Horita S, Suzuki M, Seki G, Fujita T
- Organizer
  ISN Frontier 2009
- Place of Presentation
  Florence, Italy
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] NBC1C末欠損体はERに留まりdominant negative作用を有する2009
- Author(s)
  鈴木正志、山田秀臣、堀田晶子、山崎修、関常司、藤田敏郎
- Organizer
  第52回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-06-05
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] Functional comparioson of NBCl variants expressed in Xenopus Oocytes2008
- Author(s)
  Hideomi Yamada et al
- Organizer
  Transporters 2008
- Place of Presentation
  Murten Switzerland
- Year and Date
  2008-08-28
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] Physiology and pathophysiology of Na-HCO3 cotransporter NBC12008
- Author(s)
  Seki G, H Yamada
- Organizer
  第85回日本生理学会大会
- Place of Presentation
  東京
- Year and Date
  2008-03-25
- Data Source
  KAKENHI-PROJECT-19590934
[Presentation] IRBITアイソフォームによるpNBC1の活性調節2008
- Author(s)
  山田秀臣、永吉旭士ら
- Organizer
  日本腎臓学会
- Place of Presentation
  隔岡国際会議場
- Year and Date
  2008-06-01
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] Physiology and pathophysiology of Na-HCO_3 cotransporter NBC1.2008
- Author(s)
  関常司, 山田秀臣
- Organizer
  The Journal of Physiological Science Vol 58 Suppl, S22,日本生理学会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-03-25
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] PPARg/EGFR/ERK経路を介したチアゾリンの近位尿細管作用2008
- Author(s)
  遠藤陽子、山田秀臣、李月紅、鈴木正志、山崎修、門脇孝、関常司、藤田敏郎
- Organizer
  第51回日本腎臓学会総会
- Place of Presentation
  福岡
- Year and Date
  2008-06-01
- Data Source
  KAKENHI-PROJECT-19590934
[Presentation] ヒト脳型NBC1の存在とIRBITによる活性化。IRBITアイソフォームによるpNBC1の活性調節2008
- Author(s)
  山田秀臣、永吉旭土、水谷顕洋、安東英明、御子柴克彦、関常司、藤田敏郎
- Organizer
  第51回日本腎臓学会学術総会
- Place of Presentation
  福岡
- Year and Date
  2008-06-01
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] PPARg/EGFR/ERK経路を介したチアゾリンの近位尿細管作用2008
- Author(s)
  遠藤陽子、山田秀臣、李月紅、鈴木正志、山崎修、門脇孝、関常司、藤田敏郎
- Organizer
  第51回日本腎臓学会学術総会
- Place of Presentation
  福岡
- Year and Date
  2008-06-01
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] 酸・塩基平衡関連分子の臨床2007
- Author(s)
  関常司、堀田晶子、鈴木正志、山田秀臣
- Organizer
  第37回日本腎臓学会東部会
- Place of Presentation
  埼玉
- Year and Date
  2007-10-06
- Data Source
  KAKENHI-PROJECT-19590934
[Presentation] The cytosolic mutant L522P of NBCe1 has a dominant negative effect
- Author(s)
  Yamazaki O, Yamada H, Suzuki M, Horita S, Nakamura M, Seki G, Fujita T
- Organizer
  Annual Meeting of American Society of Nephrology
- Data Source
  KAKENHI-PROJECT-23390229
[Presentation] NO/sGC/cGMP/ERK pathway mediates a unique dose-dependent stimulation of human proximal transport by angiotensin II
- Author(s)
  Shirai A, Yamazaki O, Nakamura M, Yamada H, Suzuki M, Horita S, Homma Y, Seki G
- Organizer
  Annual Meeting of American Society of Nephrology
- Data Source
  KAKENHI-PROJECT-23390229
[Presentation] Stimulatory effect of insulin on renal proximal Na transport is preserved in insulin resistance
- Author(s)
  Nakamura M, Shirai A, Yamazaki O, Yamada H, Suzuki M, Horita S, Homma Y, Seki G
- Organizer
  Annual Meeting of American Society of Nephrology
- Data Source
  KAKENHI-PROJECT-23390229
[Presentation] Transporter diseases
- Author(s)
  Yamada H
- Organizer
  Humboldt Colloquium Kyoto
- Data Source
  KAKENHI-PROJECT-23390229
[Presentation] Pioglitazone stimulates renal proximal transport through PPARg-dependent non-genomic pathway.
- Author(s)
  Seki G, Endo Y, Yamada H, Horita S, Yamazaki O, Kadowaki T, Fujita T
- Organizer
  Annual Meeting of American Society of Nephrology 2008.
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-20590971
[Presentation] Stimulatory effect of insulin on renal proximal Na transport is preserved in obesity-induced insulin resistant rats
- Author(s)
  Nakamura M, Yamazaki O, Yamada H, Suzuki M, Horita S, Seki G, Fujita T
- Organizer
  Annual Meeting of American Society of Nephrology
- Data Source
  KAKENHI-PROJECT-23390229
[Presentation] 重炭酸輸送の機能と創薬可能性について
- Author(s)
  山田秀臣
- Organizer
  生理学会　プレワークショップ
- Place of Presentation
  鹿児島
- Invited
- Data Source
  KAKENHI-PROJECT-23390229
[Presentation] NBC1 mutants showing defective plasma membrane expression are associated with migraine.
- Author(s)
  Suzuki M, Horita S, Van Paesschen W, Yamada H, Bergmans B, T Sekine T, Igarashi T, Seki G, Fujita T
- Organizer
  Annual Meeting of American Society of Nephrology 2008
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-20590971
[]
[]
[]
[]

1. SEKI George (30206619)

# of Collaborated Projects: 6 results

# of Collaborated Products: 122 results
2. HORITA Shoko (20534895)

# of Collaborated Projects: 4 results

# of Collaborated Products: 63 results
3. NOIRI Eisei (00301820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. GOTO Jun (10211252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TOKUNAGA Katsushi (40163977)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SUZUKI Masashi (90595662)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. 高橋祐二 (00372392)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YAMADA Tomoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 稲津正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 高野幸路

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamada Hideomi 山田 秀臣

YAMADA Hideomi 山田 秀臣

Research Projects

Research Products

Co-Researchers

Dent病発症の分子メカニズムと腎障害進行機序の解析

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The significance of selective insulin resistance in kidney for hypertension and renal insufficiency.

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The mechanism of regulation to occur the migrainePrincipal Investigator

Principal Investigator

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Development of new medication against proximal renal tubular acidosis

Principal Investigator

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Functional NBCe1 regulation by proteins'interactionPrincipal Investigator

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Role of cytosolic phospholipase A2 in intrarenalrenin-angiotensin system

Principal Investigator

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ナトリウム重炭酸共輸送体を標的とした近位尿細管性アシドーシスの分子治療法の開発Principal Investigator

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[Book] Nephrology Frontier2013

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[Book] 改定第８版内科学書2013

Author(s)

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[Book] 改定第８版内科学書2013

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[Book] 中外医学社2013

Author(s)

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[Book] カラー版内科学書2012

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[Book] 内科2012

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[Book] Gene Mutation2012

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[Book] 酸塩基平衡を調節するトランスポーター2011

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Yamada Hideomi 山田秀臣

YAMADA Hideomi 山田秀臣