Nakazawa Yozo 中沢洋三

… Alternative Names

NAKAZAWA Yozo 中沢洋三

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Researcher Number	60397312
Other IDs
Affiliation (Current)	2025: 信州大学, 学術研究院医学系, 教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 信州大学, 学術研究院医学系, 教授 2017: 信州大学, 医学部, 助教 2017: 信州大学, 医学部, 教授 2015: 信州大学, 医学部附属病院, 講師 2014 – 2015: 信州大学, 学術研究院医学系(医学部附属病院), 講師 … More 2014: 信州大学, 学術研究院(医学部附属病院), 講師 2012 – 2013: 信州大学, 医学部, 助教 2011: 信州大学, 医学部附属病院, 助教(特定雇用) 2007: Shinshu University, Department of Pediatrics, Senior Assistant Professor 2005 – 2006: 信州大学, 医学部, 助手 2005: 信州大学, 医学部小児医学講座, 助手 Less
Review Section/Research Field	Principal Investigator Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Pediatrics / Tumor therapeutics / Basic Section 54010:Hematology and medical oncology-related
Keywords	Principal Investigator キメラ抗原受容体 / CAR-T細胞 / 分子デザイン / がん免疫療法 / 生物物理学 / バイオフィジックス / 固形腫瘍 / 受容体型チロシンキナーゼ / 小児血液学 / T細胞性白血病 … More / 急性リンパ性白血病 / T細胞性腫瘍 / FLT3/ITD / Flt3 / Flt3/ITD / CAR-T療法 / 急性骨髄性白血病 / T細胞療法 / 神経芽腫 / 遺伝子治療 / 小児がん / GD2 / トランスポゾン / p16 / bmi-1 / ras / ARF / p15 / 若年性骨髄単球性白血病 … More Except Principal Investigator 若年性骨髄単球性白血病 / GM-CSF / キメラ抗原受容体T細胞 / 遺伝子改変T細胞 / iPS細胞 / キメラ抗原受容体 / 骨髄異形成症候群 / 白血病性幹細胞 / 小児がん / 細胞療法 / ピギーバックトランスポゾン / EPHB4 / ヒギーバックトランスポゾン / 免疫疲弊 / 横紋筋肉腫 / CAR-T細胞 / 複合治療 / GMR-CAR-T細胞 / 分子標的薬 / 造血環境 / 接着分子 / 白血病幹細胞 / PCDH17 / ＰＣＤＨ１７ / 急性骨髄性白血病 / CAR-T / 骨髄性白血病 / リガンド / 先天性食細胞異常症 / 白血病発症 / 再生医学 / 遺伝子治療 / 先天性好中球減少症 / ゲノム修飾 / 骨肉腫 / AML / MO7F Cells / histone acetylation / methylation / p15 / Stem cells / メチル化 / MO7e細胞 / 造血幹細胞 / メチル化ヒストンH3 / アセチル化ヒストンH3 / ヒストン修飾 / DNAメチル化 / p15遺伝子 / 小児急性骨髄性白血病 / RAS遺伝子異常 / PTPN11遺伝子異常 / locked nucleic acid / mutant allele-specific PCR / 若年性慢性骨髄性白血病 / CAR T細胞 / 免疫療法 / GM-CSF receptor / CD34陽性細胞 / 小児白血病 Less

Molecular design of Two-Way Player CAR-T cells to overcome disease/antigen heterogeneity of childhood, adolescent, and young adult cancersPrincipal Investigator
- Principal Investigator
  
  中沢洋三
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Shinshu University
Development of safe CAR-T cells based on logical molecular design of biophysicsPrincipal Investigator
- Principal Investigator
  
  Nakazawa Yozo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Shinshu University
Development of in-vitro assay for combination therapy using molecular targeted drug and chimeric antigen receptor T-cells for juvenile myelomonocytic leukemia
- Principal Investigator
  
  Matsuda Kazuyuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Shinshu University
Optimization of chimeric antigen receptor T cells (CAR-T) targeting GM-CSF receptor for the treatment of pediatric leukemia
- Principal Investigator
  
  Nakano Shigeru
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Shinshu University
Development of new treatment for juvenile myelomonocytic leukemia focusing on hematopoietic microenvironment
- Principal Investigator
  
  Sakashita Kazuo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Shinshu University
Developing CAR T cells for relapsed/refractory T-cell acute lymphoblastic leukemiaPrincipal Investigator
- Principal Investigator
  
  Nakazawa Yozo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Shinshu University
Development of chimeric antigen receptor T cells redirecting a growth factor receptor on human rhabdomyosarcoma
- Principal Investigator
  
  Yagyu Shigeki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kyoto Prefectural University of Medicine
Novel chimeric antigen receptor modified T cells against IGF receptor for osteosarcoma
- Principal Investigator
  
  NIshio Nobuhiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nagoya University
Development of a gene therapy for congenital phagocyte disorder using both genome editing and iPS cell technology
- Principal Investigator
  
  Koike Kenichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Shinshu University
Gene-modified T cell therapy for refractory acute myeloid leukemia harboring a FLT3/ITD mutationPrincipal Investigator
- Principal Investigator
  
  NAKAZAWA Yozo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Shinshu University
Establishment of T lymphocytes expressing chimeric antigen receptor for leukemic stem cells
- Principal Investigator
  
  KOIKE Kenichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Shinshu University
GD2-specific chimeric antigen receptor-modified T-cell therapy against advanced neuroblastomaPrincipal Investigator
- Principal Investigator
  
  NAKAZAWA Yozo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Shinshu University
若年性骨髄単球性白血病におけるポリコーム遺伝子による癌抑制経路不活化機構の解析Principal Investigator
- Principal Investigator
  
  中沢洋三
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Shinshu University
Epigenetic regulation of proliferation and differentiation of hematopoietic stem cells
- Principal Investigator
  
  KOIKE Kenichi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Shinshu University

[Book] 次世代のがん治療薬・診断のための研究開発2016
- Author(s)
  中沢洋三、共著
- Total Pages
  350
- Publisher
  技術情報出版
- Data Source
  KAKENHI-PROJECT-26461574
[Book] ネルソン小児科学2015
- Author(s)
  中沢洋三、小池健一
- Total Pages
  4
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-24390260
[Book] ネルソン小児科学第19版（翻訳）小児の組織球増殖疾患2014
- Author(s)
  中沢洋三、小池健一
- Publisher
  エルゼビアジャパン
- Data Source
  KAKENHI-PROJECT-24390260
[Journal Article] Direct delivery of piggyBac CD19 CAR T cells has potent anti-tumor activity against ALL cells in CNS in a xenograft mouse model.2020
- Author(s)
  Tanaka K, Kato I, Tanaka M, Morita D, Matsuda K, Takahashi Y, Nakahata T, Umeda K, Hiramatsu H, Adachi S, Takita J, Nakazawa Y.
- Journal Title
  
  Mol Ther Oncolytics
  
  Volume: X
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10106
[Journal Article] Comparative analysis of graft-versus-host disease prophylaxis with tacrolimus in combination with methylprednisolone or methotrexate after umbilical cord blood transplantation2020
- Author(s)
  Shigemura T, Sakashita K, Okura E, Morita D, Komori K, Kurata T, Hirabayashi K, Saito S, Tanaka M, Yanagisawa R, Nakazawa Y. Comparative analysis of graft-versus-host disease prophylaxis with tacrolimus in combination with methylprednisolone or methotrexate after umbilical cord blood transplantation
- Journal Title
  
  Int J Hematol
  
  Volume: 111 Issue: 5 Pages: 702-710
- DOI
  10.1007/s12185-020-02826-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10021, KAKENHI-PROJECT-17K10104, KAKENHI-PROJECT-17K10105, KAKENHI-PROJECT-20K08227
[Journal Article] Essential role of PTPN11 mutation in enhanced haematopoietic differentiation potential of induced pluripotent stem cells of juvenile myelomonocytic leukaemia.2019
- Author(s)
  Shigemura T, Matsuda K, Kurata T, Sakashita K, Okuno Y, Muramatsu H, Yue F, Ebihara Y, Tsuji K, Sasaki K, Nakahata T, Nakazawa Y, Koike K
- Journal Title
  
  Br J Haematol
  
  Volume: 187 Issue: 2 Pages: 163-173
- DOI
  10.1111/bjh.16060
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07816, KAKENHI-PROJECT-17K10105
[Journal Article] 血液腫瘍に対するCAR-T療法2019
- Author(s)
  中沢洋三
- Journal Title
  
  臨床血液
  
  Volume: 60 Pages: 1351-1357
- NAID
  130007724658
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10106
[Journal Article] Enhanced Expression of Anti-CD19 Chimeric Antigen Receptor in piggyBac Transposon-Engineered T Cells2018
- Author(s)
  Morita Daisuke、Nishio Nobuhiro、Saito Shoji、Tanaka Miyuki、Kawashima Nozomu、Okuno Yusuke、Suzuki Satoshi、Matsuda Kazuyuki、Maeda Yasuhiro、Wilson Matthew H.、Dotti Gianpietro、Rooney Cliona M.、Takahashi Yoshiyuki、Nakazawa Yozo
- Journal Title
  
  Molecular Therapy - Methods & Clinical Development
  
  Volume: 8 Pages: 131-140
- DOI
  10.1016/j.omtm.2017.12.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19311, KAKENHI-PROJECT-15K09648
[Journal Article] Aberrant methylation of protocadherin 17 and its prognostic value in pediatric acute lymphoblastic leukemia2017
- Author(s)
  Uyen TN, Sakashita K, Al-Kzayer LF, Nakazawa Y, Kurata T, Koike K.
- Journal Title
  
  Pediatric Blood & Cancer
  
  Volume: in press Issue: 3 Pages: 200-5
- DOI
  10.1002/pbc.26259
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04874, KAKENHI-PROJECT-26461575
[Journal Article] IFR4/MUM1-positive lymphoma in Waldeyer ring with co-expression of CD5 and CD10.2017
- Author(s)
  Chen L, Al-Kzayer LF, Liu T, Kobayashi N, Nakazawa Y, Koike K.
- Journal Title
  
  Pediatr Blood Cancer
  
  Volume: 64 Issue: 2 Pages: 311-314
- DOI
  10.1002/pbc.26236
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04874
[Journal Article] Increasing Risk of Disturbed Root Development in Permanent Teeth in Childhood Cancer Survivors Undergoing Cancer Treatment at Older Age.2017
- Author(s)
  Tanaka M, Kamata T, Yanagisawa R, Morita D, Saito S, Sakashita K, Shiohara M, Kurita H, Koike K, Nakazawa Y.
- Journal Title
  
  J Pediatr Hematol Oncol.
  
  Volume: 39 Issue: 3 Pages: e150-e154
- DOI
  10.1097/mph.0000000000000788
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10021, KAKENHI-PROJECT-15H04874
[Journal Article] Dramatic Reduction in Tumor Size During 5 Months of Pazopanib Therapy in Combination With Ifosfamide, Carboplatin, and Etoposide in an Early Infant With Progressive Soft Tissue Sarcoma.2017
- Author(s)
  Watanabe T, Kurata T, Sano K, Suzuki S, Kaneko T, Motobayashi M, Shigemura T, Sumi T, Koike K, Nakazawa Y
- Journal Title
  
  J Pediatr Hematol Oncol
  
  Volume: 39 Issue: 2 Pages: 154-6
- DOI
  10.1097/mph.0000000000000628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04874
[Journal Article] Pazopanib Therapy in Combination With Ifosfamide, Carboplatin, and Etoposide in an Early Infant With Progressive Soft Tissue Sarcoma.2017
- Author(s)
  Watanabe T, Kurata T, Sano K, Suzuki S, Kaneko T, Motobayashi M, Shigemura T, Sumi T, Koike K, Nakazawa Y.
- Journal Title
  
  J Pediatr Hematol Oncol
  
  Volume: 39 Pages: 154-156
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04874
[Journal Article] Increasing Risk of Disturbed Root Development in Permanent Teeth in Childhood Cancer Survivors Undergoing Cancer Treatment at Older Age.2017
- Author(s)
  Tanaka M, Kamata T, Yanagisawa R, Morita D, Saito S, Sakashita K, Shiohara M, Kurita H, Koike K, Nakazawa Y.
- Journal Title
  
  J Pediatr Hematol Oncol.
  
  Volume: 39
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04874
[Journal Article] 小児血液腫瘍に対するキメラ抗原受容体を用いた遺伝子改変T細胞療法の開発2016
- Author(s)
  中沢洋三
- Journal Title
  
  臨床血液
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461574
[Journal Article] Intrathecal donor lymphocyte infusion for isolated leukemia relapse in the central nervous system following allogeneic stem cell transplantation: a case report and literature review.2016
- Author(s)
  Yanagisawa R, Nakazawa Y, Sakashita K, Saito S, Tanaka M, Shiohara M, Shimodaira S, Koike K.
- Journal Title
  
  Int J Hematol
  
  Volume: 103 Issue: 1 Pages: 107-11
- DOI
  10.1007/s12185-015-1902-1
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04874, KAKENHI-PROJECT-26860790
[Journal Article] Loss of Mismatched HLA on the Leukemic Blasts of Patients With Relapsed Lymphoid Malignancies Following Bone Marrow Transplantation From Related Donors With HLA Class II Mismatches in the Graft Versus Host Direction.2016
- Author(s)
  Hirabayashi K, Kurata T, Horiuchi K, Saito S, Shigemura T, Tanaka M, Yanagisawa R, Matsuda K, Sakashita K, Koike K, Nakazawa Y
- Journal Title
  
  Pediatr Blood Cancer
  
  Volume: 63 Issue: 4 Pages: 709-11
- DOI
  10.1002/pbc.25819
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04874, KAKENHI-PROJECT-26860789
[Journal Article] Anti-proliferative effects of T cells expressing a ligand-based chimeric antigen receptor against CD116 on CD34(+) cells of juvenile myelomonocytic leukemia2016
- Author(s)
  Nakazawa Y, Matsuda K, Kurata T, Sueki A, Tanaka M, Sakashita K, Imai C, Wilson MH, Koike K
- Journal Title
  
  J Hematol Oncol
  
  Volume: 9 Issue: 1 Pages: 27-27
- DOI
  10.1186/s13045-016-0256-3
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461574, KAKENHI-PROJECT-25461581, KAKENHI-PROJECT-15H04874, KAKENHI-PROJECT-15K19177, KAKENHI-PROJECT-16K10015
[Journal Article] Viral load and ganciclovir (GCV) concentration in cerebrospinal fluid of patients successfully treated with GCV or valGCV for human herpesvirus 6 encephalitis/myelitis following umbilical cord blood transplantation.2016
- Author(s)
  D. Morita, K. Hirabayashi, Y. Katsuyama, H. Morokawa, M. Motobayashi, T. Kurata, T. Shigemura, M. Tanaka, Y. Inaba, K. Koike, Y. Nakazawa.
- Journal Title
  
  Transpl Infect Dis
  
  Volume: 18 Issue: 5 Pages: 773-776
- DOI
  10.1111/tid.12579
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04874
[Journal Article] In vitro expansion of CD34+CD38- cells under stimulation with hematopoietic growth factors on AGM-S3 cells in juvenile myelomonocytic leukemia.2015
- Author(s)
  Sakashita K, Kato I, Daifu T, Saida S, Hiramatsu H, Nishinaka Y, Ebihara Y, Ma F, Matsuda K, Saito S, Hirabayashi K, Kurata T, Uyen LT, Nakazawa Y, Tsuji K, Heike T, Nakahata T, Koike K.
- Journal Title
  
  Leukemia
  
  Volume: in press
- NAID
  120007110642
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390260
[Journal Article] Reduced-toxicity myeloablative conditioning consisting of 8-Gy total body irradiation, cyclophosphamide and fludarabine for pediatric hematological malignancies.2015
- Author(s)
  Hirabayashi K, Nakazawa Y, Sakashita K, Kurata T, Saito S, Yoshikawa K, Tanaka M, Yanagisawa R, Koike K.
- Journal Title
  
  Sci Rep
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390260
[Journal Article] キメラ抗原受容体(CAR)遺伝子改変T細胞療法2015
- Author(s)
  中沢洋三
- Journal Title
  
  がん分子標的治療
  
  Volume: 13 Pages: 59-65
- Data Source
  KAKENHI-PROJECT-26461574
[Journal Article] Subcutaneous abscess due to the basidiomycete Phellinus mori in a patient with chronic granulomatous disease.2015
- Author(s)
  Shigemura T, Nakazawa Y, Amano Y, Sudo A, Watanabe M, Kobayashi M, Kobayashi N, Koike K, Agematsu K, Nishimura K.
- Journal Title
  
  Infection
  
  Volume: 43 Issue: 3 Pages: 371-5
- DOI
  10.1007/s15010-015-0724-7
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04874
[Journal Article] Dramatic improvement in the multifocal positron emission tomography findings of a young adult with chronic granulomatous disease following allogeneic hematopoietic stem cell transplantation.2015
- Author(s)
  Shigemura T, Nakazawa Y, Hirabayashi K, Kobayashi N, Sakashita K, Agematsu K, Koike K.
- Journal Title
  
  J Clin Immunol
  
  Volume: 35 Issue: 1 Pages: 84-6
- DOI
  10.1007/s10875-014-0113-5
- Data Source
  KAKENHI-PROJECT-15H04874
[Journal Article] Anti-leukemic potency of piggyBac-mediated CD19-specific T cells against refractory Philadelphia chromosome-positive acute lymphoblastic leukemia.2014
- Author(s)
  Saito S, Nakazawa Y, Sueki A, Matsuda K, Tanaka M, Yanagisawa R, Maeda Y, Sato Y, Okabe S, Inukai T, Sugita K, Wilson MH, Rooney CM, Koike K.
- Journal Title
  
  Cytotherapy
  
  Volume: 16 Issue: 9 Pages: 1257-1269
- DOI
  10.1016/j.jcyt.2014.05.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591544, KAKENHI-PROJECT-26461574
[Journal Article] Anti-leukemic potency of piggyBac-mediated CD19-specific T cells against refractory Philadelphia chromosome-positive acute lymphoblastic leukemia2014
- Author(s)
  Saito S, Nakazawa Y, Sueki A, Matsuda K, Tanaka M, Yanagisawa R, Maeda Y, Sato Y, Okabe S, Inukai T, Sugita K, Wilson MH, Rooney CM, and Koike K.
- Journal Title
  
  Cytotherapy
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591533
[Journal Article] Anti-leukemic potency of piggyBac-mediated CD19-specific T cells against refractory Philadelphia chromosome-positive acute lymphoblastic leukemia.2014
- Author(s)
  Saito S, Nakazawa Y, Sueki A, Matsuda K, Tanaka M, Yanagisawa R, Maeda Y, Sato Y, Okabe S, Inukai T, Sugita K, Wilson MH, Rooney CM, Koike K.
- Journal Title
  
  Cytotherapy
  
  Volume: 16 Pages: 1257-69
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390260
[Journal Article] Myeloid progenitors with PTPN11 and non-RAS pathway gene mutations are refractory to treatment with 6-mercaptopurine in juvenile myelomonocytic leukemia.2014
- Author(s)
  Matsuda K, Nakazawa Y, Iwashita C, Kurata T, Hirabayashi K, Saito S, Tanaka M, Yoshikawa K, Yanagisawa R, Sakashita K, Sasaki S, Honda T, Koike K.
- Journal Title
  
  Leukemia
  
  Volume: 28 Pages: 1545-8
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390260
[Journal Article] Successful cord blood transplantation after repeated transfusions of unmobilized neutrophils in addition to antifungal treatment in an infant with chronic granulomatous disease complicated by invasive pulmonary aspergillosis.2013
- Author(s)
  Shigemura T, Nakazawa Y, Yoshikawa K, Hirabayashi K, Saito S, Kobayashi N, Sakashita K, Shiohara M, Wada T, Shimodaira S, Agematsu K and Koike K.
- Journal Title
  
  Transfusion
  
  Volume: 54 Issue: 3 Pages: 516-21
- DOI
  10.1111/trf.12325
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390260, KAKENHI-PROJECT-24591542
[Journal Article] Usefulness of allogeneic hematopoietic stem cell transplantation in first complete remission for pediatric blastic plasmacytoid dendritic cell neoplasm with skin involvement: a case report and review of literature.2013
- Author(s)
  Sakashita K, Saito S, Yanagisawa R Miyuki Tanaka M, Yoshikawa K, Hirabayashi K, Tsukahara K, Motobayashi M, Nakazawa Y, Koike K.
- Journal Title
  
  Pediatr Blood Cancer
  
  Volume: 60 Issue: 11 Pages: E140-E142
- DOI
  10.1002/pbc.24622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390260
[Journal Article] Long-term haematological improvement after non-intensive or no chemotherapy in juvenile myelomonocytic leukaemia and poor correlation with adult myelodysplasia spliceosome-related mutations.2012
- Author(s)
  Matsuda K, Sakashita K
- Journal Title
  
  Br J Haematol.
  
  Volume: 157 Issue: 5 Pages: 647-50
- DOI
  10.1111/j.1365-2141.2012.09063.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591154, KAKENHI-PROJECT-24390260
[Journal Article] Food allergy after cord blood transplantation in children.2012
- Author(s)
  Sakashita K, Koike K.
- Journal Title
  
  Br J Haematol.
  
  Volume: 158 Issue: 5 Pages: 672-6
- DOI
  10.1111/j.1365-2141.2012.09204.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591154, KAKENHI-PROJECT-24390260
[Journal Article] Replaced platelet concentrates containing a new additive solution, M-sol: safety and efficacy for pediatric patients.2012
- Author(s)
  Yanagisawa R, Sakashita K
- Journal Title
  
  Transfusion.
  
  Volume: 53 Issue: 9 Pages: 2053-60
- DOI
  10.1111/trf.12025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591154, KAKENHI-PROJECT-24390260
[Journal Article] Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations.2007
- Author(s)
  Matsuda K, Shimada A, Yoshida N, Ogawa A, Watanabe A, Yajima S, Iizuka S, Koike K, Yanai F, Kawasaki K, Yanagimachi M, Kikuchi A, Ohtsuka Y, Hidaka E, Yamauchi K, Tanaka M, Yanagisawa R, Nakazawa Y, Shiohara M, Manabe A, Kojima S, Koike K.
- Journal Title
  
  Blood 109
  
  Pages: 5477-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390300
[Journal Article] A possible role for the production of multiple HLA antibodies in fatal platelet transfusion refractoriness after peripheral blood stem cell transplantation from the mother in a patient with relapsed leukemia2007
- Author(s)
  Nakazawa Y, Saito S. Hasegawa Y. Yanagisawa Y. Sakashita K. Kamijo T. Miyazaki T. Sato S. Ikeda H. Ikebuchi K. Koike K
- Journal Title
  
  Transfusion 47
  
  Pages: 326-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390300
[Journal Article] A complex karyotype. including a three-way translocation generating a NUP98-HOXD13 transcript. in an infant with acute myeloid leukemia.2007
- Author(s)
  Hidaka E, Tanaka M, Matsuda K, Ishikawa-Matsumura M, Yamauchi K, Sano K, Honda T, Wakui K, Yanagisawa R, Nakazawa Y, Sakashita K, Shiohara M, Ishii E, Koike K.
- Journal Title
  
  Cancer Genet Cytogenet. 176
  
  Pages: 137-43
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390300
[Journal Article] A complex karyotype, including a three-way translocation generating a NUP98-HOXD13 transcript, in an infant with acute myeloid leukemia.2007
- Author(s)
  Hidaka E, Tanaka M, Matsuda K, Ishikawa-Matsumura M, Yamauchi K, Sano K, Honda T, Wakui K, Yanagisawa R, Nakazawa Y, Sakashita K, Shiohara M, Ishii E, Koike K.
- Journal Title
  
  Cancer Genet Cytogenet 176
  
  Pages: 137-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390300
[Journal Article] A possible role for the production of multiple HLA antibodies in fatal platelet transfusion refractoriness after peripheral blood stem cell transplantation from the mother in a patient with relapsed leukemia2007
- Author(s)
  Nakazawa Y, Saito S, Hasegawa Y, Yanagisawa Y, Sakashita K, Kamijo T, Miyazaki T, Sato S, Ikeda H, Ikebuchi K, Koike K
- Journal Title
  
  Transfusio 47
  
  Pages: 326-34
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390300
[Journal Article] Acquirement of loss of the wild-type NRAS locus with aggres sive disease progression in a patient with juvenile myelomonocytic leukemia and a heterozygous NRAS mutation.2007
- Author(s)
  Matsuda K, Nakazawa Y. Sakashita K, Shiohara M, Yamauchi K, Koike K.
- Journal Title
  
  Haematologica. 92
  
  Pages: 1576-1578
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390300
[Journal Article] Acquirement of loss of the wild-type NRAS locus with aggressive disease progression in a patient. with juvenile myelomonocytic leukemia and a heterozygous NRAS mutation.2007
- Author(s)
  Matsuda K. Nakazawa Y. Sakashita K. Shiohara M. Yamauchi K. Koike K.
- Journal Title
  
  Haematologica. 92
  
  Pages: 1576-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390300
[Journal Article] Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations2007
- Author(s)
  Matsuda K, Shimada A, Yoshida N. Ogawa A, Watanabe A, Yajima S, Iizuka S, Koike K, Yanai F, Kawasaki K, Yanagimachi M, Kikuchi A, Ohtsuka Y, Hidaka E, Yamauchi K, Tanaka M, Yanagisawa R, Nakazawa Y, Shiohara M, Manabe A. Kojima S, Koike K.
- Journal Title
  
  blood, 109
  
  Pages: 5477-80
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390300
[Journal Article] Chromosomal change during 6-mercaptopurine(6-MP)therapy in juvenile myelomonocytic leukemia: the growth of a 6-MP-refractory clone that already exists at onset.2006
- Author(s)
  Matsuda K, Matsuzaki S, Miki J, Hidaka E, Yanagisawa R, Nakazawa Y, Sakashita K, Kamijo T, Asami K, Sano K, Koike K
- Journal Title
  
  Leukemia 20
  
  Pages: 485-490
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390300
[Journal Article] Chromosomal change during 6-mercaptopurine (6-MP) therapy in juvenile myelomonocytic leukemia : the growth of a 6-MP-refractory clone that already exists at onset.2006
- Author(s)
  Matsuda K, Matsuzaki S, Miki J, Hidaka E, Yanagisawa R, Nakazawa Y, Sakashita K, Kamijo T, Asami K, Sano K, Koike K
- Journal Title
  
  Leukemia 20
  
  Pages: 485-485
- Data Source
  KAKENHI-PROJECT-17390300
[Journal Article] Development of two cytogenetically abnormal clones from multipotential hematopoietic stem cells in a patient with juvenile myelomonocytic leukemia.2005
- Author(s)
  Matsuzaki S. Matsuda K, Miki J, Nakazawa Y, Sakashita K, Kamijo T, Hidaka E, Koike K
- Journal Title
  
  Leukemia Res, 29
  
  Pages: 1069-1072
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390300
[Journal Article] Development of two cytogenetically abnormal clones from multipotential hematopoietic stem cells in a patient with juvenile myelomonocytic leukemia.2005
- Author(s)
  Matsuzaki S, Matsuda K, Miki J, Nakazawa Y, Sakashita K, Kamijo T, Hidaka E, Koike K
- Journal Title
  
  Leukemia Res 29
  
  Pages: 1069-1072
- Data Source
  KAKENHI-PROJECT-17390300
[Patent] 特許権2022
- Inventor(s)
  中沢洋三、平林耕一、丸山悠太
- Industrial Property Rights Holder
  中沢洋三、平林耕一、丸山悠太
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-012674
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-20H03639
[Patent] 高効率な遺伝子改変細胞の作製方法2019
- Inventor(s)
  中沢　洋三、田中　美幸、師川　紘一、成松　翔伍
- Industrial Property Rights Holder
  中沢　洋三、田中　美幸、師川　紘一、成松　翔伍
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-17K10103
[Patent] ＣＡＲ発現免疫細胞を含む細胞集団の製造方法2019
- Inventor(s)
  柳生茂希、中沢洋三、田中美幸、中村加世子、ほか3名
- Industrial Property Rights Holder
  京都府公立大学法人、国立大学法人信州大学、ブライトパス・バイオ
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17K07224
[Patent] 遺伝子改変細胞及びその作製方法2017
- Inventor(s)
  中沢洋三，松田和之，中野茂
- Industrial Property Rights Holder
  国立大学法人信州大学・キッセイ薬品工業株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-17K10103
[Patent] 殺細胞効果を有するキメラ抗原受容体遺伝子改変リンパ球2017
- Inventor(s)
  柳生茂希、中沢洋三、家原知子、細井創
- Industrial Property Rights Holder
  京都府公立大学法人、国立大学法人信州大学
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-17K07224
[Patent] 遺伝子改変細胞及びその作製方法2017
- Inventor(s)
  中沢洋三、松田和之、中野茂
- Industrial Property Rights Holder
  国立大学法人信州大学・キッセイ薬品工業株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-17K10103
[Patent] キメラ抗原受容体を発現する遺伝子改変Ｔ細胞の調製方法2016
- Inventor(s)
  西尾信博、中沢洋三、田中美幸、盛田大介、高橋義行
- Industrial Property Rights Holder
  名古屋大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016-10-07
- Overseas
- Data Source
  KAKENHI-PROJECT-15K09648
[Patent] 遺伝子改変細胞及びその作製方法2016
- Inventor(s)
  中沢洋三、松田和之、中野茂
- Industrial Property Rights Holder
  信州大学、（株）キッセイ薬品工業
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-182293
- Filing Date
  2016-09-16
- Data Source
  KAKENHI-PROJECT-26461574
[Presentation] トランスポゾン法で作成したGD2特異的CART細胞は神経芽腫細胞に対して抗腫瘍効果を示す．Development of piggyBac Transposon-Mediated GD2 specific CAR-T Cells targeting Neuroblastoma.2019
- Author(s)
  9.Tomida A, Yagyu S, Yamashima K, Yoshida H, Miyachi M, Tsuchiya K, Iehara T, Nakazawa Y, Hosoi H.
- Organizer
  第61回日本小児血液・がん学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K07224
[Presentation] PiggyBacトランスポゾンを用いた非ウイルス遺伝子改変CAR-T療法の開発2019
- Author(s)
  中沢洋三
- Organizer
  第23回日本がん免役学会総会
- Data Source
  KAKENHI-PROJECT-17K10103
[Presentation] CAR-T細胞療法の今後の展開2019
- Author(s)
  中沢洋三
- Organizer
  第8回日本免疫・細胞治療学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10103
[Presentation] Development of PiggyBac Transposon Mediated CAR-T Cells Targeting EPHB4 for Pediatric Solid Tumors．2019
- Author(s)
  Yagyu S, Tomida A, Kubo H, Yamashima K, Kikuchi K, Nakamura K, Tanaka M, Nakazawa Y, Iehara T, Hosoi H.
- Organizer
  51st Annual Congress of the International Society of Paediatric Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07224
[Presentation] 霊長類モデルを用いたpiggyBacトランスポゾン遺伝子改変GMR CAR-細胞の安全性評価.2019
- Author(s)
  Morokawa H, Tanaka M, Saito S, Mochizuki H, Shimoi A, Yagyu S, Nakazawa Y.
- Organizer
  第61回日本小児血液・がん学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K07224
[Presentation] Optimization of PiggyBac Transposon-Based Gene Delivery by the MaxCyte Scalable Transfection System for Manufacturing Chimeric Antigen Receptor-T Cells．2019
- Author(s)
  Tomida A, Yagyu S, Yamashima K, Kubo H, Iehara T, Nakazawa Y, Hosoi H.
- Organizer
  22nd Annual Meeting of American Society of Gene and Cell Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07224
[Presentation] 急性骨髄性白血病に対するCAR-T細胞療法2019
- Author(s)
  中沢洋三
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10103
[Presentation] 血液腫瘍に対するCAR-T療法2019
- Author(s)
  中沢洋三
- Organizer
  第81回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10106
[Presentation] 血液腫瘍に対するCAR-T療法2019
- Author(s)
  中沢洋三
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10103
[Presentation] Development of piggyBac CAR-T cells - Experiences in Japan．2018
- Author(s)
  14.Yagyu S，Nakazawa Y
- Organizer
  6th piggyBac CART meeting, Houston, TX, USA, 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07224
[Presentation] Function, phenotype, and tonic signaling of GD2-CART cells using piggyBac transposon gene transfer.2018
- Author(s)
  Yagyu S，Nakamura K，Morita D，Tanaka M，Nakazawa Y.
- Organizer
  5th piggybac CART meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07224
[Presentation] 重症先天性好中球減少症責任遺伝子ELANE変異を認めた無症候性母親の解析2018
- Author(s)
  重村倫成、小林法元、上松一永、中沢洋三、小原収
- Organizer
  第1回日本免疫不全・自己炎症学会
- Data Source
  KAKENHI-PROJECT-15H04874
[Presentation] 臍帯血移植後の輸血関連サイトメガロウイルス血症の検討2018
- Author(s)
  重村倫成、小森一寿、盛田大介、平林耕一、倉田敬、齋藤章治、田中美幸、柳沢龍、坂下一夫、中沢洋三
- Organizer
  第40回日本造血細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-15H04874
[Presentation] piggyBac transposon mediated chimeric antigen receptor T cell therapy for pediatric solid tumors.2018
- Author(s)
  15.Yagyu S，Nakamura K，Morita D，Tanaka M，Iehara T, Nakazawa Y, Hosoi H．
- Organizer
  0th Annual Meeting of American Society of Gene and Cell Therapy, Chicago, LA, USA, 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07224
[Presentation] PiggyBac Mediated T cells Expressing Anti-CD19 Chimeric Antigen Receptor for a Clinical Trial2017
- Author(s)
  Nobuhiro Nishio, Yozo Nakazawa, Motoharu Hamada, Satoshi Suzuki, Miyuki Takana, Daisuke Morita, Nozomu Kawashima, Yusuke Okuno, Atsushi Narita, Asahito Hama, Hideki Muramatsu, Seiji Kojima, Yoshiyuki Takahashi
- Organizer
  第8回日本血液学会国際シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09648
[Presentation] Chimeric Antigen Receptor T cells redirecting EPHB4 for the Treatment of Human Rhabdomyosarcoma.2017
- Author(s)
  Nakamura K，Yagyu S，Morita D，Kikuchi K，Iehara T，Hosoi H，Nakazawa Y.
- Organizer
  第2回日本遺伝子細胞治療学会若手研究会
- Data Source
  KAKENHI-PROJECT-17K07224
[Presentation] Chimeric Antigen Receptor T cells redirecting EPHB4 for the Treatment of Human Rhabdomyosarcoma.2017
- Author(s)
  Yagyu S，Nakamura K，Morita D，Kikuchi K，Iehara T，Hosoi H，Nakazawa Y.
- Organizer
  第23回日本遺伝子細胞治療学会学術集会
- Data Source
  KAKENHI-PROJECT-17K07224
[Presentation] Non-virally engineered CAR T cells for CD116-positive myeloid neoplasms2017
- Author(s)
  中沢洋三
- Organizer
  第23回日本遺伝子細胞治療学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10103
[Presentation] GM-CSF receptor-targeted CAR T cells for myeloid neoplasms2017
- Author(s)
  中沢洋三
- Organizer
  第59回日本小児血液がん学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10103
[Presentation] キメラ抗原受容体T細胞療法2017
- Author(s)
  中沢洋三
- Organizer
  第23回国際個別化医療学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10103
[Presentation] PiggyBac Mediated T cells Expressing anti CD19 Chimeric Antigen Receptor for a Clinical Trial2017
- Author(s)
  Nobuhiro Nishio, Yozo Nakazawa, Motoharu Hamada, Satoshi Suzuki, Miyuki Takana, Daisuke Morita, Nozomu Kawashima, Yusuke Okuno, Atsushi Narita, Asahito Hama, Hideki Muramatsu, Wilson H. Matthew, Cliona M. Rooney, Gianpietro Dotti, Seiji Kojima, Yoshiyuki Takahashi
- Organizer
  第20回American Society of Gene and Cell Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09648
[Presentation] 免疫療法の進歩と展望2017
- Author(s)
  中沢洋三
- Organizer
  第120回日本小児科学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10103
[Presentation] PiggyBac遺伝子改変CD19キメラ抗原受容体T細胞療法のFirst in Human試験にむけた基盤研究2017
- Author(s)
  西尾信博、鈴木哲、奥野友介、中沢洋三、田中美幸、盛田大介、濱田太立、川島希、成田敦、村松秀城、濱麻人、小島勢二、高橋義行
- Organizer
  第６回日本血液学会東海地方会
- Data Source
  KAKENHI-PROJECT-15K09648
[Presentation] Chimeric Antigen Receptor T cells redirecting EPHB4 for the Treatment of Human Rhabdomyosarcoma2017
- Author(s)
  Yagyu S，Nakamura K，Morita D，Kikuchi K，Iehara T，Hosoi H，Nakazawa Y.
- Organizer
  第59回日本小児血液が学会学術集会
- Data Source
  KAKENHI-PROJECT-17K07224
[Presentation] Development of T cells redirected to GM-CSF receptor with a ligand-based CAR for myeloid neoplasms2016
- Author(s)
  Nakano T, Morita D, Matsuda K, Ohnota H, Hongo K, Koike K, Nakazawa Y
- Organizer
  日本血液学会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15H04874
[Presentation] Detection of integration sites of CD19 chimeric antigen receptor gene in a non-viral gene transfer system.2016
- Author(s)
  Motoharu Hamada, Yusuke Okuno, Nobuhiro Nishio, Matthew H. Wilson, Seiji Kojima, Yozo Nakazawa, and Yoshiyuki Takahashi
- Organizer
  American Society of Gene and Cell Therapy
- Place of Presentation
  Washington, DC, USA
- Year and Date
  2016-05-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09648
[Presentation] PiggyBac mediated T cells expressing CD19 chimeric antigen receptor for a “first in human” clinical trial2016
- Author(s)
  Nobuhiro Nishio, Yozo Nakazawa, Motoharu Hamada, Satoshi Suzuki, Miyuki Takana, Daisuke Morita, Nozomu Kawashima, Yusuke Okuno, Atsushi Narita, Asahito Hama, Hideki Muramatsu, Wilson H. Matthew, Cliona M. Rooney, Gianpietro Dotti, Seiji Kojima, Yoshiyuki Takahashi
- Organizer
  第58回日本小児血液・がん学会学術集会
- Place of Presentation
  品川プリンスホテル（東京都品川区）
- Year and Date
  2016-12-15
- Data Source
  KAKENHI-PROJECT-15K09648
[Presentation] Ligand-based chimeric antigen receptor-modified T cells targeting CD116 for the treatment of acute myeloid leukemia2016
- Author(s)
  Shigeru Nakano, Daisuke Morita, Kazuyuki Matsuda, Hideki Ohnota, Kazuhiro Hongo, Kenichi Koike, Yozo Nakazawa
- Organizer
  日本遺伝子細胞治療学会
- Place of Presentation
  虎ノ門ヒルズフォーラム、東京
- Year and Date
  2016-07-28
- Data Source
  KAKENHI-PROJECT-26461574
[Presentation] Detection of Integration Sites of CD19 Chimeric Antigen Receptor Gene in a Non-viral Gene Transfer System.2016
- Author(s)
  Motoharu Hamada, Yusuke Okuno, Nobuhiro Nishio, Matthew H. Wilson, Nozomu Kawashima, Atsushi Narita, Hideki Muramatsu, Asahito Hama, Seiji Kojima, Yozo Nakazawa, Yoshiyuki Takahashi.
- Organizer
  The 7th JSH 国際シンポジウム
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県淡路市）
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-15K09648
[Presentation] Genome-wide Profile of Integration Sites of Chimeric Antigen Receptor (CAR) Gene in PiggyBac-modified Human T Cells.2016
- Author(s)
  Motoharu Hamada, Yusuke Okuno, Nobuhiro Nishio, Nozomu Kawashima, Atsushi Narita, Hideki Muramatsu, Asahito Hama, Seiji Kojima, Yozo Nakazawa, and Yoshiyuki Takahashi
- Organizer
  第58回日本小児血液・がん学会学術集会
- Place of Presentation
  品川プリンスホテル（東京都品川区）
- Year and Date
  2016-12-15
- Data Source
  KAKENHI-PROJECT-15K09648
[Presentation] PiggyBac mediated CD19 chimeric antigen receptor modified T cells for a first in human clinical trial.2016
- Author(s)
  Nobuhiro Nishio, Yozo Nakazawa, Motoharu Hamada, Satoshi Suzuki, Miyuki Takana, Daisuke Morita, Nozomu Kawashima, Yusuke Okuno, Atsushi Narita, Asahito Hama, Hideki Muramatsu, Wilson H. Matthew, Cliona M. Rooney, Gianpietro Dotti, Seiji Kojima, Yoshiyuki Takahashi.
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K09648
[Presentation] Development of T cells redirected to GM-CSF receptor with a ligand-based CAR for myeloid neoplasms2016
- Author(s)
  Shigeru Nakano, Daisuke Morita, Kazuyuki Matsuda, Hideki Ohnota, Kazuhiro Hongo, Kenichi Koike, Yozo Nakazawa
- Organizer
  日本血液学会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26461574
[Presentation] Cancer immunotherapy using chimeric antigen receptors: advances, issues, and future directions2015
- Author(s)
  中沢洋三
- Organizer
  第21回日本遺伝子治療学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2015-07-24
- Invited
- Data Source
  KAKENHI-PROJECT-26461574
[Presentation] Gene-modified T-cell therapy using chimeric antigen receptors for childhood neoplasms2015
- Author(s)
  中沢洋三
- Organizer
  第57回日本小児血液がん学会学術集会
- Place of Presentation
  甲府富士屋ホテル（山梨県甲府市）
- Year and Date
  2015-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-26461574
[Presentation] Gene-modified T-cell therapy using chimeric antigen receptors．for childhood hematological malignancies2015
- Author(s)
  中沢洋三
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢市アートホール（石川県金沢市）
- Year and Date
  2015-10-16
- Invited
- Data Source
  KAKENHI-PROJECT-26461574
[Presentation] 難治性がんに対するキメラ抗原受容体を用いた遺伝子改変Ｔ細胞療法2015
- Author(s)
  中沢洋三
- Organizer
  第4回日本免疫・細胞治療学会学術集会
- Place of Presentation
  ベルサール九段（東京都千代田区）
- Year and Date
  2015-12-05
- Invited
- Data Source
  KAKENHI-PROJECT-26461574
[Presentation] Potency of piggyBac transposon-mediated CD19-specific T-cells against drug-resistant Philadelphia chromosome-positive acute lymphoblastic leukemia2014
- Author(s)
  Shoji Saito, Yozo Nakazawa, Miyuki Tanaka, Ryu Yanagisawa, Akane Sueki, Kazuyuki Matsuda, Matthew H. Wilson, Cliona Rooney, Kenichi Koike
- Organizer
  International Society of Cell Therapy
- Place of Presentation
  フランス
- Data Source
  KAKENHI-PROJECT-23591533
[Presentation] PiggyBac Transposon-Mediated Cancer Immunotherapy2014
- Author(s)
  Yozo Nakazawa
- Organizer
  第17回日米細胞・遺伝子治療会議
- Place of Presentation
  ワシントンDC
- Year and Date
  2014-03-06
- Data Source
  KAKENHI-PROJECT-23591533
[Presentation] 若年性骨髄単球性白血病に対するGM-CSF受容体を標的とした遺伝子改変T細胞療法の開発2013
- Author(s)
  中沢洋三、末木茜、松田和之、坂下一夫、小池健一
- Organizer
  第55回日本小児血液・がん学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23591533
[Presentation] 神経芽腫における新規糖脂質抗原の同定2013
- Author(s)
  末木茜、中沢洋三、松田和之、小池健一
- Organizer
  第55回日本小児血液・がん学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23591533
[Presentation] 若年性骨髄単球性白血病に対するGM-CSF受容体を標的とした遺伝子改変T細胞療法の開発2013
- Author(s)
  中沢　洋三、小池健一、他
- Organizer
  第55回日本小児血液・がん学会学術集会
- Place of Presentation
  ヒルトン福岡シーホーク
- Data Source
  KAKENHI-PROJECT-24390260
[Presentation] CD19-specific T-cell therapy for refractory Philadelphia-chromosome-positive acute lymphoblastic leukemia using PiggyBac transposon-based gene modification and low autoserum-containing, but xeno-free and tumor cell line-free culture system2012
- Author(s)
  Saito S, Nakazawa Y, Tanaka M, Yanagisawa R, Maeda Y, Inukai T, Sugita K, Wilson MH, Rooney CM, Koike K.
- Organizer
  15th American Society of Gene and Cell Therapy Annual Meeting
- Place of Presentation
  Philadelphia
- Data Source
  KAKENHI-PROJECT-23591533
[Presentation] キメラ抗原受容体を用いた遺伝子改変T細胞療法2012
- Author(s)
  中沢洋三
- Organizer
  第34回日本造血細胞移植学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23591533
[Presentation] 難治性急性リンパ性白血病に対するCD 19特異的遺伝子改変T細胞療2012
- Author(s)
  斎藤章治, 中沢洋三, 平林耕一, 小池健一, 他
- Organizer
  第115回日本小児科学会学術集会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24390260
[Presentation] 薬剤耐性Ph陽性急性リンパ性白血病に対するpiggyBacトランスポゾン遺伝子改変CD19特異的T細胞療法の開発2012
- Author(s)
  齋藤章治、中沢洋三、田中美幸、柳沢龍、松田和之、前田裕弘、犬飼岳史、杉田完爾、小池健一
- Organizer
  第54回日本小児血液・がん学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591533
[Presentation] CD19-specific T-cell therapy for drug-resistant Philadelphia chromosome-positive acute lymphoblastic leukemia using piggyBac transposons2012
- Author(s)
  Nakazawa Y, Saito S, Tanaka M, Koike K.
- Organizer
  第18回日本遺伝子治療学会総会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23591533
[Presentation] 網膜芽細胞腫に対するpiggyBacトランスポゾン遺伝子改変GD2特異的T細胞療法の開発2012
- Author(s)
  平林耕一、中沢洋三、齋藤章治、松田和之、金兼弘和、小池健一
- Organizer
  第54回日本小児血液・がん学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591533
[Presentation] 進行性神経芽腫に対するキメラ抗原受容体を用いた遺伝子改変T細胞療法2012
- Author(s)
  中沢洋三
- Organizer
  第54回日本小児血液・がん学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591533
[Presentation] トランスポゾンを用いた慢性肉芽腫症に対する新たな遺伝子治療法の開発2012
- Author(s)
  重村倫成、中沢洋三、松田和之、小池健一
- Organizer
  第115回日本小児科学会学術集会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24390260
[Presentation] Acquirement of loss of the wild-type NRASlocus with aggressive disease progression in a patient with juvenile myelomonocytic leukemia and a heterozygous NRAS mutation2007
- Author(s)
  Matsuda, K., Nakazawa, Y., Sakashita, K., Shiohara, M., Yamauchi, K., Koike, K
- Organizer
  Pediatr Blood Cancer
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390300
[Presentation] A complex karyotype, including a three-way translocation generating a NUP98-HOXD13 transcript, in an infant with acute myeloid leukemia2007
- Author(s)
  Hidaka, E., Tanaka, M., Matsuda, K., Ishilawa-Matsumura, M., Yamauchi, K., Sano, K., Honda, T., Wakui, K., Yanagisawa, R., Nakazawa, Y., Sakashita, K., Shiohara, M., Ishii, E., Koike, K
- Organizer
  Cancer Genet Cytogenet
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390300
[Presentation] t(8;21)急性骨髄性白血病に対する化学療法および同種骨髄移植後の微少残存病変の解析2007
- Author(s)
  田中美幸、柳沢龍、中沢洋三、塩原正明、小池健一
- Organizer
  第110回日本小児科学会学術集会
- Place of Presentation
  京都市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390300
[Presentation] A possible role for the production of multiple HLA antibodies in fatal platelet transfusion refractoriness after peripheral blood stem cell transplantation from the mother in a patient with relapsed leukemia2007
- Author(s)
  Nakazawa, Y., Saito, S., Hasegawa, Y., Yanagisawa, Y., Sakashita, K., Kamijo, T., Miyazaki, T., Sato, S., Ikeda, H., Ikebuchi, K., Koike, K
- Organizer
  Transfusion
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390300
[Presentation] Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations2007
- Author(s)
  Matsuda, K., Shimada, A., Yoshida, N., Ogawa, A., Watanabe, A., Yajima, S., Iizuka, S., Koike, K., Yanai, F., Kawasaki, K., Yanagimachi, M., Kikuchi, A., Ohtsuka, Y., Hidaka, E., Yamauchi, K., Tanaka, M., Yanagisawa, R., Nakazawa, Y., Shiohara, M., Manabe, A., Kojima, S., Koike, K
- Organizer
  Blood
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390300
[Presentation] ★t(8;21)急性骨髄性白血病に対する化学療法および同種骨髄移植後の微少残存病変の解析2007
- Author(s)
  田中美幸、柳沢龍、中沢洋三、塩原正明、小池健一
- Organizer
  第110回日本小児科学会学術集会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-17390300
[Presentation] 急性骨髄性白血病に対する同種骨髄移植後のAML1-ETOキメラ遺伝子による微少残存病変の解析2006
- Author(s)
  田中美幸、柳沢龍、中沢洋三、塩原正明、小池健一、松田和之、鈴木剛史、川久保雅友
- Organizer
  第68回日本血液学会・第48回日本臨床血液学会
- Place of Presentation
  福岡市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390300
[Presentation] Chromosomal change during 6-mercaptopurine (6-MP) therapy in juvenile myelomonocytic leukemia : the growth of a 6-MP-refractory clone that already exists at onset2006
- Author(s)
  Matsuda, K., Matsuzaki, S., Mild, J., Hidaka, E., Yanagisawa, R., Nakazawa, Y., Sakashita, K., Kamijo, T., Asami, K., Sano, K., Koike, K
- Organizer
  Leukemia
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390300
[Presentation] 全身放射線照射量を減量した前処置による造血幹細胞移植の治療成績2006
- Author(s)
  柳沢龍、田中美幸、中沢洋三、塩原正明、上條岳彦、小池健一
- Organizer
  第109回日本小児科学会学術集会
- Place of Presentation
  金沢市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390300
[Presentation] Three-wayおよびfour-way translocationを示した乳児白血病の2例2005
- Author(s)
  田中美幸, 柳沢龍, 中沢洋三, 塩原正明, 上條岳彦, 小池健一, 松田和之、鈴木剛史、日高恵以子
- Organizer
  臨床血液学会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390300
[Presentation] Development of two cytogenetically abnormal clones from multipotential hematopoietic stem cells in a patient with juvenile myelomonocytic leukemia2005
- Author(s)
  Matsuzaki, S., Matsuda, K., Miki, J., Nakazawa, Y., Sakashita, K., Kamijo, T., Hidaka, E., Koike, K
- Organizer
  Leukemia Res
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390300
[Presentation] PiggyBac transposon-mediated cancer immunotherapy
- Author(s)
  Yozo Nakazawa
- Organizer
  17th US-Japan Cellular and Gene Therapy Conference
- Place of Presentation
  アメリカ
- Invited
- Data Source
  KAKENHI-PROJECT-23591533
[Presentation] キメラ抗原受容体（CAR）を用いた遺伝子改変T細胞療法
- Author(s)
  中沢洋三
- Organizer
  日本がん免疫学会
- Place of Presentation
  松山市ひめぎんホール
- Year and Date
  2014-07-30 – 2014-08-01
- Invited
- Data Source
  KAKENHI-PROJECT-26461574
[Presentation] Potency of piggyBac transposon-mediated CD19-specific T-cells against drug-resistant Philadelphia chromosome-positive acute lymphoblastic leukemia
- Author(s)
  Shoji Saito, Yozo Nakazawa, Miyuki Tanaka, Ryu Yanagisawa, Akane Sueki, Kazuyuki Matsuda, Matthew H. Wilson, Cliona Rooney, Kenichi Koike
- Organizer
  International Society for Cellular Thrapy
- Place of Presentation
  フランス（パリ）
- Year and Date
  2014-04-23 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-26461574

1. KOIKE Kenichi (40143979)

# of Collaborated Projects: 3 results

# of Collaborated Products: 46 results
2. SAKASHITA Kazuo (10345746)

# of Collaborated Projects: 3 results

# of Collaborated Products: 23 results
3. Nakano Shigeru (30791313)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SHIOHARA Masaaki (00293514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
5. NIshio Nobuhiro (00586430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
6. Matsuda Kazuyuki (00647084)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Yagyu Shigeki (10572547)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
8. 上條岳彦 (90262708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
9. 重村倫成 (70623916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
10. 菊地顕 (40453104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. 梅澤公二 (00609258)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MURAMATSU Hideki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. OKUNO Yusuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. ITO Masafumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 犬飼岳史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 柳沢龍

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 川島希

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakazawa Yozo 中沢 洋三

NAKAZAWA Yozo 中沢 洋三

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Molecular design of Two-Way Player CAR-T cells to overcome disease/antigen heterogeneity of childhood, adolescent, and young adult cancersPrincipal Investigator

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Development of safe CAR-T cells based on logical molecular design of biophysicsPrincipal Investigator

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Developing CAR T cells for relapsed/refractory T-cell acute lymphoblastic leukemiaPrincipal Investigator

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Gene-modified T cell therapy for refractory acute myeloid leukemia harboring a FLT3/ITD mutationPrincipal Investigator

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GD2-specific chimeric antigen receptor-modified T-cell therapy against advanced neuroblastomaPrincipal Investigator

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若年性骨髄単球性白血病におけるポリコーム遺伝子による癌抑制経路不活化機構の解析Principal Investigator

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Nakazawa Yozo 中沢洋三

NAKAZAWA Yozo 中沢洋三