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OGIHARA Takeshi  荻原 健

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… Alternative Names

荻原 健  オギハラ タケシ

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Researcher Number 60399772
Affiliation (Current) 2025: 順天堂大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help 2011 – 2022: 順天堂大学, 医学部, 准教授
2005 – 2006: 順天堂大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Metabolomics / Basic Section 54040:Metabolism and endocrinology-related
Keywords
Principal Investigator
β細胞 / 膵β細胞 / 糖尿病 / 膵島 / iNOS / 炎症 / メチル化 / NF-kB / Set9 / インスリン … More / 膵発生 / scRNA-seq / heterogeneity / トランスクリプトーム解析 / 内分泌細胞分化 / α細胞新生 / 糖尿病再生医療 / グルカゴン / 内分泌細胞 / α細胞 / サイクリンB1 / エストラジオール / 細胞増殖 / 妊娠 / p53 / Estradiol / Ccnb1 / Pbk / NF-κB / p65 / NF-kb / Set7/9 / NK-kB / mafA / nkx6.1 / neurogenin3 / 再生医療 / 転写因子 Less
  • Research Projects

    (5 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (3 People)
  •  Deciphering alpha-cell heterogeneity using a novel reporter mousePrincipal Investigator

    • Principal Investigator
      Ogihara Takeshi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      Juntendo University
  •  The role of PDZ binding kinase in beta cell proliferation during pregnancyPrincipal Investigator

    • Principal Investigator
      OGIHARA Takeshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Juntendo University
  •  The role of methyltransferase Set7/9 in pancreatic beta cellsPrincipal Investigator

    • Principal Investigator
      Ogihara Takeshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Juntendo University
  •  The role of methyltransferase, Set7/9 in islet inflammationPrincipal Investigator

    • Principal Investigator
      OGIHARA Takeshi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Juntendo University
  •  膵臓特異的転写因子を用いた膵β細胞の再生医療の研究Principal Investigator

    • Principal Investigator
      荻原 健
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Metabolomics
    • Research Institution
      Juntendo University

All 2021 2018 2016 2015 2013 Other

All Journal Article Presentation

  • [Journal Article] Enhanced Expression of the Key Mitosis Regulator Cyclin B1 Is Mediated by PDZ-Binding Kinase in Islets of Pregnant Mice.2018

    • Author(s)
      Uesato T, Ogihara T, Hara A, Iida H, Miyatsuka T, Fujitani Y, Takeda S, Watada H.
    • Journal Title

      J Endocr Soc.

      Volume: 2 Issue: 3 Pages: 207-219

    • DOI

      10.1210/js.2017-00338

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09765, KAKENHI-PROJECT-17K09846
  • [Journal Article] SET7/9 Enzyme Regulates Cytokine-induced Expression of Inducible Nitric-oxide Synthase through Methylation of Lysine 4 at Histone 3 in the Islet β Cell.2015

    • Author(s)
      Fujimaki K, Ogihara T, Morris DL, Oda H, Iida H, Fujitani Y, Mirmira RG, Evans-Molina C, Watada H
    • Journal Title

      J Biol Chem

      Volume: 290 Issue: 27 Pages: 16607-18

    • DOI

      10.1074/jbc.m115.661777

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461345, KAKENHI-PROJECT-25461364
  • [Presentation] 新規レポーターマウスを用いたα細胞新生・分化機構の解明2021

    • Author(s)
      氷室 美和, 宮塚 健, 若林侑香, 荻原 健, 西田友哉, 大島 茂, 岡本隆一, 綿田裕孝
    • Organizer
      第94回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K08895
  • [Presentation] 新規レポーターマウスを用いた膵α細胞新生機構の解明2021

    • Author(s)
      氷室 美和, 宮塚 健, 若林侑香, 荻原 健, 西田友哉, 大島 茂, 岡本隆一, 綿田裕孝
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-20K08895
  • [Presentation] 妊娠期のβ細胞増殖におけるPBKの役割2018

    • Author(s)
      上里忠好、荻原健、板倉敦夫、竹田省、綿田裕孝
    • Organizer
      第42回日本産婦人科栄養・代謝研究会
    • Data Source
      KAKENHI-PROJECT-17K09846
  • [Presentation] Bilateral property of methyltransferase Set7/9 in beta cell function2016

    • Author(s)
      荻原 健、藤巻杏子、綿田裕孝
    • Organizer
      日本糖尿病学会年次学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-26461345
  • [Presentation] Set7/9 regulates cytokine-induced expression of iNOS in beta cells through histone modification.2013

    • Author(s)
      藤巻杏子、荻原 健、福中彩子、藤谷与士夫、綿田裕孝
    • Organizer
      American Diabetes Association 73rd Scientific Sessions
    • Place of Presentation
      シカゴ
    • Data Source
      KAKENHI-PROJECT-23591324
  • [Presentation] Set7/9はiNOS発現制御を介して膵島炎症に関与する2013

    • Author(s)
      藤巻杏子、荻原健、原朱美、藤谷与士夫、綿田裕孝
    • Organizer
      第56回日本糖尿病学会年次学術集会
    • Place of Presentation
      熊本
    • Year and Date
      2013-05-17
    • Data Source
      KAKENHI-PROJECT-23591324
  • [Presentation] Set7/9 regulates cytokine-induced expression of iNOS in Beta cells through histone modification2013

    • Author(s)
      Kyoko KUDO-FUJIMAKI, Takeshi OGIHARA, Yoshio FUJITANI, Hirotaka WATADA
    • Organizer
      The American Diabetes Association 73^<rd> Scientific Sessions
    • Place of Presentation
      アメリカシカゴ
    • Data Source
      KAKENHI-PROJECT-23591324
  • [Presentation] Set7/9 regulates cytokine-induced expresson of iNOS in beta-cell through histone modification2013

    • Author(s)
      Kyoko Kudo-Fujimaki, Takeshi Ogihara, Yoshio Fujitani, Hirotaka Watada
    • Organizer
      American Diabetes Association 73rd Scientific Sessions
    • Place of Presentation
      アメリカ シカゴ
    • Data Source
      KAKENHI-PROJECT-23591324
  • [Presentation] Set7/9はiNOS発現制御を介して膵島炎症に関与する

    • Author(s)
      藤巻杏子、荻原 健、藤谷与士夫、綿田裕孝
    • Organizer
      第56回日本糖尿病学会年次学術集会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-23591324
  • [Presentation] Set7/9はiNOS発現制御を介して膵島炎症に関与する

    • Author(s)
      藤巻杏子 荻原健 原朱美 藤谷与士夫 綿田裕孝
    • Organizer
      日本糖尿病学会年次学術集会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-23591324
  • 1.  宮塚 健 (60622363)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 2.  藤谷 与士夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  原 朱美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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