Kubota Takaaki 久保田高明

… Alternative Names

KUBOTA Takaaki 久保田高明

久保田高明クボタタカアキ

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Researcher Number	60399954
Other IDs	https://orcid.org/0000-0002-3553-5844
Affiliation (Current)	2024: 岡山大学, 医歯薬学域, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 岡山大学, 医歯薬学域, 教授 2020: 岡山大学, 医歯薬学総合研究科, 教授 2017 – 2019: 昭和薬科大学, 薬学部, 教授 2015: 昭和薬科大学, 薬学部, 教授 2014: 北海道大学, 大学院薬学研究院, 准教授 … More 2012 – 2014: 北海道大学, 薬学研究科(研究院), 准教授 2010 – 2011: 北海道大学, 大学院・薬学研究院, 准教授 2008 – 2009: 北海道大学, 大学院・先端生命科学研究院, 准教授 2007: 北海道大学, 大学院・薬学研究院, 講師 2006: 北海道大学, 大学院薬学研究院, 講師 2005: Hokkaido Univ., Grad.School of Pharm.Sci., Lecturer, 大学院・薬学研究科, 講師 2002: 北海道大学, 大学院・薬学研究科, 特別研究員(PD) Less
Review Section/Research Field	Principal Investigator Natural medicines / Chemical pharmacy / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Science and Engineering Except Principal Investigator Science and Engineering / Living organism molecular science / Basic Section 38020:Applied microbiology-related / Natural medicines / Chemical pharmacy / Biological Sciences
Keywords	Principal Investigator マクロリド / 渦鞭毛藻 / 天然有機化合物 / 海綿動物 / トリパノソーマ / アルカロイド / 海洋生物 / 生合成 / ポリケチド / 殺細胞活性 … More / 絶対立体配置 / 共渦鞭毛藻 / Amphidinolide C / 海産天然物 / アンタゴニスト / Pregnane X Receptor / 核内受容体 / 抗原虫 / 抗真菌 / 抗感染症 / マラリア / 原虫感染症 / 深在性真菌症 / 抗感染症薬 / 抗マラリア / 細胞毒性 / 生物活性天然物 / 生物活性物質 / cDNAライブラリー / RNA-Seq / 次世代シーケンサー / Amphidinolide / Amphidinium sp. … More Except Principal Investigator 分子標的 / リード化合物 / 天然資源 / チューブリン / アクチン / Symbiodiniaceaeとバクテリア / 遺伝子クラスターの水平伝播 / 二次代謝産物 / 共生関係の崩壊 / 褐虫藻とバクテリア / サンゴ共生微生物 / Read Compound / Natural Resource / Molecular Target / Tubulin / Actin / Nocardia sp. / 病原性放線菌 / 免疫抑制剤 / 抗腫瘍剤 / System L / アミノ酸輸送体 / Nocardia brasiliensis / 放線菌 / ブラシリカルジンA / 海洋生物 / 天然物ライブラリー / 海洋天然物 / 機能性天然分子 / 殺細胞活性 / アルカロイド / 海洋由来真菌 / 光ピンセット / ナノバイオ / 生物・生体工学 / 計測工学 / 応用光学・量子光工学 / バイオプローブ / 医薬リード / がん治療 / 天然薬物 / がん分子標的 / 抗イエジマリド抗体 / 立体化学 / コスミドライブラリー / ポリケチド合成酵素 / Eudistoma cf.rigida / イエジマリド Less

Understanding of the symbiotic mechanism based on the technological development for utilization of metabolic products of coral symbiotic microorganisms
- Principal Investigator
  
  將口栄一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38020:Applied microbiology-related
- Research Institution
  Okinawa Institute of Science and Technology Graduate University
Development of nuclear receptor PXR antagonists from marine natural productsPrincipal Investigator
- Principal Investigator
  
  KUBOTA Takaaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Okayama University
Development of new anti-infective drugs from dinoflagellatePrincipal Investigator
- Principal Investigator
  
  KUBOTA Takaaki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Showa Pharmaceutical University
Development of new antitrypanosomal drugs from marine alkaloidsPrincipal Investigator
- Principal Investigator
  
  KUBOTA Takaaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Showa Pharmaceutical University
  Hokkaido University
Development of new antitumor agents and immunosuppressive agents using brasilicardin-A as a lead compound
- Principal Investigator
  
  KOBAYASHI Jun'ichi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Natural medicines
- Research Institution
  Hokkaido University
渦鞭毛藻由来マクロリドの特異な生合成経路の解明Principal Investigator
- Principal Investigator
  
  久保田高明
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Hokkaido University
Research and development of bioactive marine natural products
- Principal Investigator
  
  KOBAYASHI Jun'ichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Hokkaido University
創薬素材としての細胞骨格系機能性分子の探索
- Principal Investigator
  
  小林淳一
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Hokkaido University
がん分子標的に特異的に作用する天然薬物の開発
- Principal Investigator
  
  小林淳一
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
フォトンフォース計測技術を用いた細胞系ダイナミック分析法の開発
- Principal Investigator
  
  笹木敬司
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Hokkaido University
蛋白質リン酸化を標的とした新規抗腫瘍性シーズの探索
- Principal Investigator
  
  津田正史
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Hokkaido University
抗腫瘍性マクロリド・イエジマリド類の真の生産微生物の解明
- Principal Investigator
  
  KOBAYASHI Jun'ichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Living organism molecular science
- Research Institution
  Hokkaido University
Research and development of bioactive natural products targeting cytoskeleton.
- Principal Investigator
  
  KOBAYASHI Jun'ichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  HOKKAIDO UNIVERSITY
渦鞭毛藻由来マクロリドamphidinolide Cの立体化学と生合成経路の解明Principal Investigator
- Principal Investigator
  
  久保田高明
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Chemical pharmacy
- Research Institution
  Hokkaido University

[Book] The Alkaloids: Chemistry and Biology (Vol. 84, Chapter One: The manzamine alkaloids)2020
- Author(s)
  Kubota, T.; Kurimoto, S.; Kobayashi, J.
- Total Pages
  124
- Publisher
  Academic Press
- ISBN
  9780128209820
- Data Source
  KAKENHI-PROJECT-17K08345
[Book] The Alkaloids: Chemistry and Biology (Vol. 84, Chapter One: The manzamine alkaloids)2020
- Author(s)
  Kubota, T.; Kurimoto, S.; Kobayashi, J.
- Total Pages
  124
- Publisher
  Academic Press
- ISBN
  9780128209820
- Data Source
  KAKENHI-PROJECT-20K07116
[Book] Bioactive metabolites from marine dinoflagellates2010
- Author(s)
  Kobayashi, J.; Kubota, T.
- Publisher
  In Comprehensive Natural Products II : Chemistry and Biology; Mander, L., Lui, H.-W., Eds.; Elsevier Science : Oxford
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Zamamiphidins B and C, Manzamine-Related Alkaloids from an <i>Amphimedon</i> sp. Marine Sponge Collected in Okinawa2022
- Author(s)
  Kurimoto Shin-ichiro、Suzuki Shoichi、Ueno Mayumi、Fromont Jane、Kobayashi Jun’ichi、Kubota Takaaki
- Journal Title
  
  Journal of Natural Products
  
  Volume: 85 Issue: 9 Pages: 2226-2231
- DOI
  10.1021/acs.jnatprod.2c00395
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07116
[Journal Article] Ma'edamines E and F, rare bromotyrosine alkaloids possessing a 1,2,3,5-tetrasubstituted pyridinium moiety from an Okinawan marine sponge Suberea sp.2022
- Author(s)
  Kurimoto Shin-ichiro、Okamoto Ayano、Seino Satsuki、Fromont Jane、Kobayashi Jun'ichi、Kubota Takaaki
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 103 Pages: 153985-153985
- DOI
  10.1016/j.tetlet.2022.153985
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07116
[Journal Article] Macrocarquinoid D, New Meroterpenoid from Brown Alga, Sargassum macrocarpum2022
- Author(s)
  Sinoda, S.; Kurimoto, S.; Kubota, T.; Sekiguchi, M.
- Journal Title
  
  Heterocycles
  
  Volume: - Issue: 6 Pages: 1141-1141
- DOI
  10.3987/com-22-14651
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16398, KAKENHI-PROJECT-20K07116
[Journal Article] Teuchamaedol A, a new neo-clerodane diterpenoid from the aerial parts of Teucrium chamaedrys2022
- Author(s)
  Kurimoto Shin-ichiro、Wakabayashi Koji、Sasaki Yu F.、Nakamura Takanori、Kubota Takaaki
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 100 Pages: 153890-153890
- DOI
  10.1016/j.tetlet.2022.153890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07116
[Journal Article] Macrocarquinoids A-C, new meroterpenoids from Sargassum macrocarpum2021
- Author(s)
  Niwa, H.; Kurimoto, S.; Kubota, T.; Sekiguchi, M.
- Journal Title
  
  J. Nat. Med.
  
  Volume: 75 Issue: 1 Pages: 194-200
- DOI
  10.1007/s11418-020-01449-y
- NAID
  40022465236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07116, KAKENHI-PROJECT-19K16398
[Journal Article] Kamiohnoyneosides A and B, two new polyacetylene glycosides from flowers of edible Chrysanthemum "Kamiohno"2021
- Author(s)
  Kurimoto, S.; Fujita, H.; Kawaguchi, S.; Sasaki, Y. F.; Nakamura, T.; Kubota, T.
- Journal Title
  
  J. Nat. Med.
  
  Volume: 75 Issue: 1 Pages: 167-172
- DOI
  10.1007/s11418-020-01443-4
- NAID
  40022466260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07116, KAKENHI-PROJECT-19K16398
[Journal Article] Integrated omics unveils the multifaceted secondary metabolism landscape of a basal dinoflagellate2020
- Author(s)
  Beedessee, G.; Kubota, T.; Arimoto, A.; Nishitsuji, K.; Waller, R. F.; Hisata, K.; Yamasaki, S.; Satoh, N.; Kobayashi, J.; Shoguchi, E.
- Journal Title
  
  BMC Biol.
  
  Volume: 18 Issue: 1 Pages: 139-139
- DOI
  10.1186/s12915-020-00873-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07116
[Journal Article] Ma’edamines C and D, New Bromotyrosine Alkaloids Possessing a Unique Tetrasubstituted Pyridinium Moiety from an Okinawan Marine Sponge Suberea sp.2019
- Author(s)
  Kurimoto Shin-ichiro、Seino Satsuki、Fromont Jane、Kobayashi Jun’ichi、Kubota Takaaki
- Journal Title
  
  Organic Letters
  
  Volume: 21 Issue: 21 Pages: 8824-8826
- DOI
  10.1021/acs.orglett.9b03457
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16398, KAKENHI-PROJECT-17K08345
[Journal Article] Ishigadine A, a new canthin-6-one alkaloid from an Okinawan marine sponge Hyrtios sp.2018
- Author(s)
  Takahashi, H.; Kurimoto, S.; Kobayashi, J.; Kubota, T.
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 59 Issue: 51 Pages: 4500-4502
- DOI
  10.1016/j.tetlet.2018.11.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08345, KAKENHI-PROJECT-16K18903
[Journal Article] Ceratinadins E and F, new bromotyrosine alkaloids from an Okinawan marine sponge Pseudoceratina sp.2018
- Author(s)
  Kurimoto, S.; Ohno, T.; Hokari, R.; Ishiyama, A.; Iwatsuki, M.; Omura, S.; Kobayashi, J.; Kubota, T.
- Journal Title
  
  Mar. Drugs
  
  Volume: 16 Issue: 12 Pages: 463-463
- DOI
  10.3390/md16120463
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08345, KAKENHI-PROJECT-16K18903
[Journal Article] Symbiodinolactone A, a new 12-membered macrolide from symbiotic marine dinoflagellate Symbiodinium sp.2018
- Author(s)
  Kurimoto, S.; Iinuma, Y.; Kobayashi, J.; Kubota, T.
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 59 Issue: 51 Pages: 4496-4499
- DOI
  10.1016/j.tetlet.2018.11.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08345
[Journal Article] Hyrtinadines B and C, new azepino-indole-type alkaloids from an Okinawan marine sponge Hyrtios sp.2016
- Author(s)
  Kubota, T.; Nakamura, K.; Sakai, K.; Fromont, J.; Gonoi, T.; Kobayashi, J.
- Journal Title
  
  Chem. Pharm. Bull.
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460115
[Journal Article] Tyrokeradines G and H, new bromotyrosine alkaloids from an Okinawan Verongid sponge2015
- Author(s)
  Kubota, T.; Watase, S.; Sakai, K.; Fromont, J.; Gonoi, T.; Kobayashi, J.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 25 Issue: 22 Pages: 5221-5223
- DOI
  10.1016/j.bmcl.2015.09.061
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460115, KAKENHI-PROJECT-25305012
[Journal Article] Amphidinin G, a putative precursor of amphidinin A from marine dinoflagellate Amphidinium sp.2015
- Author(s)
  Kubota, T.; Iwai, T.; Ishiyama, H.; Sakai, K.; Gonoi, T.; Kobayashi, J.
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 56 Issue: 8 Pages: 990-993
- DOI
  10.1016/j.tetlet.2015.01.058
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460115, KAKENHI-PROJECT-25670043
[Journal Article] Iejimalide C Is a Potent V-ATPase Inhibitor, and Induces Actin Disorganization2014
- Author(s)
  Kazami, S.; Takaine, M.; Itoh, H.; Kubota, T.; Kobayashi, J.; Usui, T.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 37 Issue: 12 Pages: 1944-1947
- DOI
  10.1248/bpb.b14-00548
- NAID
  130004703917
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460115, KAKENHI-PROJECT-25670043
[Journal Article] Amphidinins C-F, amphidinolide Q analogues from marine dinoflagellate Amphidinium sp.2014
- Author(s)
  Kubota, T.; Iwai, T.; Sakai, K.; Gonoi, T.; Kobayashi, J.
- Journal Title
  
  Org. Lett.
  
  Volume: 16 Issue: 21 Pages: 5624-5627
- DOI
  10.1021/ol502685z
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460115, KAKENHI-PROJECT-25670043
[Journal Article] Absolute configuration of amphidinin A2014
- Author(s)
  Iwai, T.; Kubota, T.; Kobayashi, J.
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 77 Issue: 6 Pages: 1541-1544
- DOI
  10.1021/np5003065
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460115, KAKENHI-PROJECT-25670043
[Journal Article] Taurospongins B and C, new acetylenic fatty acid derivatives possessing a taurine amide residue from a marine sponge of the family Spongiidae2014
- Author(s)
  Kubota, T.; Suzuki, H.; Takahashi-Nakaguchi, A.; Fromont, J.; Gonoi, T.; Kobayashi, J.
- Journal Title
  
  RSC Adv.
  
  Volume: 4 Issue: 22 Pages: 11073-11079
- DOI
  10.1039/c3ra47796g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460115, KAKENHI-PROJECT-25670043
[Journal Article] Nakijiquinone S and Nakijinol C, New Meroterpenoids from a Marine Sponge of the Family Spongiidae2014
- Author(s)
  Suzuki, H.; Kubota, T.; Takahashi-Nakaguchi, A.; Fromont, J.; Gonoi, T.; Kobayashi, J.
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 62 Issue: 2 Pages: 209-212
- DOI
  10.1248/cpb.c13-00810
- NAID
  130003390762
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460115, KAKENHI-PROJECT-25670043
[Journal Article] Nagelamide I and 2,2′-Didebromonagelamide B, New Dimeric Bromopyrrole–Imidazole Alkaloids from a Marine Sponge <i>Agelas</i> sp.2014
- Author(s)
  Iwai, T.; Kubota, T.; Fromont, J.; Kobayashi, J.
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 62 Issue: 2 Pages: 213-216
- DOI
  10.1248/cpb.c13-00821
- NAID
  130003390763
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460115, KAKENHI-PROJECT-25670043
[Journal Article] Hyrtimomines D and E, bisindole alkaloids from a marine sponge Hyrtios sp.2013
- Author(s)
  Tanaka, N.; Momose, R.; Takahashi, Y.; Kubota, T.; Takahashi-Nakaguchi, A.; Gonoi, T.; Fromont, J.; Kobayashi, J.
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 54 Issue: 31 Pages: 4038-4040
- DOI
  10.1016/j.tetlet.2013.05.073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670043, KAKENHI-PROJECT-25860074
[Journal Article] Pyrinodemins E and F, new 3-alkylpyridine alkaloids from sponge Amphimedon sp.2011
- Author(s)
  Kura, K.; Kubota, T.; Fromont, J. Kobayashi, J.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 21 Issue: 1 Pages: 267-270
- DOI
  10.1016/j.bmcl.2010.11.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Hyrtioseragamines A and B, new alkaloids from the sponge Hyrtios species2011
- Author(s)
  Takahashi, Y.; Iinuma, Y.; Kubota, T.; Tsuda, M.; ekiguchi, M.; Mikami, Y.; Fromont, J.; Kobayashi, J.
- Journal Title
  
  Org. Lett.
  
  Volume: 13 Issue: 4 Pages: 628-631
- DOI
  10.1021/ol102867x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Nakijinamines C-E, new heteroaromatic alkaloids from the sponge Suberites species2011
- Author(s)
  Takahashi, Y.; Kubota, T.; Shibazaki, A.; Gonoi, T.; Fromont, J.; Kobayashi, J.
- Journal Title
  
  Org. Lett.
  
  Volume: 13 Issue: 12 Pages: 3016-3019
- DOI
  10.1021/ol2008473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Eudistomidins H-K, new b-carboline alkaloids from the Okinawan marine tunicate Eudistoma glaucus2011
- Author(s)
  Suzuki, T.; Kubota, T.; Kobayashi, J.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 21 Issue: 14 Pages: 4220-4223
- DOI
  10.1016/j.bmcl.2011.05.072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Untenolide A, a new polyketide from an Okinawan marine sponge Plakortis sp.2010
- Author(s)
  Ishiguro, Y.; Kubota, T.; Fromont, J.; Shiro, M.; Kobayashi, J.
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 51 Issue: 31 Pages: 4023-4026
- DOI
  10.1016/j.tetlet.2010.05.085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Amphidinolide C3, a new cytotoxic 25-membered macrolide from marine dinoflagellate Amphidinium sp.2010
- Author(s)
  Kubota, T.; Suzuki, A.; Yamada, M.; Baba, S.; Kobayashi, J.
- Journal Title
  
  Heterocycles
  
  Volume: 82 Issue: 1 Pages: 333-338
- DOI
  10.3987/com-10-s(e)3
- NAID
  40017418836
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Platisidines A-C, N-methyl pyridinium alkaloids from an Okinawan marine sponge of Plakortis species2010
- Author(s)
  Kubota, T.; Ishiguro, Y.; Yamamoto, S.; Fromont, J.; Kobayashi, J.
- Journal Title
  
  Heterocycles
  
  Volume: 80 Issue: 2 Pages: 1407-1412
- DOI
  10.3987/com-09-s(s)131
- NAID
  40016991501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Ceratinadins A-C, new bromotyrosine alkaloids from an Okinawan marine sponge Pseudoceratina sp.2010
- Author(s)
  Kon, Y.; Kubota, T.; Shibazaki A.; Gonoi, T.; Kobayashi, J.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 20 Issue: 15 Pages: 4569-4572
- DOI
  10.1016/j.bmcl.2010.06.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Eudistomidin G, a new b-carboline alkaloid from the Okinawan marine tunicate Eudistoma glaucus and structure revision of eudistomidin B2010
- Author(s)
  Takahashi, Y.; Ishiyama, H.; Kubota, T.; Kobayashi, J.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 20 Issue: 14 Pages: 4100-4103
- DOI
  10.1016/j.bmcl.2010.05.071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Nakijiquinones J-R, sesquiterpenoid quinones from Okinawan marine sponges2010
- Author(s)
  Takahashi, Y.; Ushio, M.; Kubota, T.; Yamamoto, S.; Fromont, J.; Kobayashi, J.
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 73 Issue: 3 Pages: 467-471
- DOI
  10.1021/np900470e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Zamamidine C, 3,4-dihydro-6-hydroxy-10,11-epoxymanzamine A, and 3,4-dihydromanzamine J N-oxide, new manzamine alkaloids from sponge Amphimedon sp.2009
- Author(s)
  Yamada, M.; Takahashi, Y.; Kubota, T.; Fromont, J.; Ishiyama, A.; Otoguro, K.; Yamada, H.; Omura, S; Kobayashi, J.
- Journal Title
  
  Tetrahedron
  
  Volume: 65 Issue: 11 Pages: 2313-2317
- DOI
  10.1016/j.tet.2009.01.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Bromopyrrole alkaloids from marine sponges of the genus Agelas2009
- Author(s)
  Yasuda, T.; Araki, A.; Kubota, T.; Ito, J.; Mikami, Y.; Fromont, J.; Kobayashi, J.
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 72 Issue: 3 Pages: 488-491
- DOI
  10.1021/np800645q
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Total synthesis of amphidinolactone A and its absolute configuration2009
- Author(s)
  Hangyou, M.; Ishiyama, H.; Takahashi, Y.; Kubota, T.; Kobayashi, J.
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 50 Issue: 13 Pages: 1475-1477
- DOI
  10.1016/j.tetlet.2009.01.065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Tyrokeradines A and B, new bromotyrosine alkaloids with an imidazolyl-quinolinone moiety from a Verongid sponge2009
- Author(s)
  Mukai, H.; Kubota, T.; Aoyama, K.; Mikami, Y.; Fromont, J.; Kobayashi, J.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 19 Issue: 5 Pages: 1337-1339
- DOI
  10.1016/j.bmcl.2009.01.056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Benzosceptrin C, a new dimeric bromopyrrole alkaloid from sponge Agelas sp.2009
- Author(s)
  Kubota, T.; Araki, A.; Yasuda, T.; Tsuda, M.; Fromont, J.; Aoyama, K.; Mikami, Y.; Walchli, M. R.; Kobayashi, J.
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 50 Issue: 52 Pages: 7268-7270
- DOI
  10.1016/j.tetlet.2009.10.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Plakoridine C, a novel piperidine alkaloid from an Okinawan marine sponge Plakortis sp.2009
- Author(s)
  Ishiguro, Y.; Kubota, T.; Ishiuchi, K.; Fromont, J.; Kobayashi, J.
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 50 Issue: 26 Pages: 3202-3204
- DOI
  10.1016/j.tetlet.2009.01.135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Nakijiquinones E and F, new dimeric sesquiterpenoid quinones from marine sponge2009
- Author(s)
  Takahashi, Y.; Kubota, T.; Kobayashi, J.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 17 Issue: 6 Pages: 2185-2188
- DOI
  10.1016/j.bmc.2008.10.080
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Benzoscentrin C, a new dimeric bromopyrrole alkaloid from sponge Agelas sp.2009
- Author(s)
  Kubota, T.
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 50 Pages: 7268-7270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Total synthesis and biological evaluation of amphidinolide V and analogues2009
- Author(s)
  Furstner, A.; Flugge, S.; Larionov, O.; Takahashi, Y.; Kubota, T.; Kobayashi, J.
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 15 Issue: 16 Pages: 4011-4029
- DOI
  10.1002/chem.200802068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Nagelamides Q and R, novel dimeric bromopyrrole alkaloids from sponges Agelas sp.2009
- Author(s)
  Araki, A.; Kubota, T.; Aoyama, K.; Mikami, Y.; Fromont, J.; Kobayashi, J.
- Journal Title
  
  Org. Lett.
  
  Volume: 11 Issue: 8 Pages: 1785-1788
- DOI
  10.1021/ol900328c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Zamamidines A & B, new manzamine alkaloids from sponge Amphimedon species2009
- Author(s)
  Takahashi, Y.; Kubota, T.; Fromont, J.; Kobayashi, J.
- Journal Title
  
  Org. Lett.
  
  Volume: 11 Issue: 1 Pages: 21-24
- DOI
  10.1021/ol802251q
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Nagelamides M and N, new bromopyrrole alkaloids from sponge Agelas species2008
- Author(s)
  Kubota, T.
- Journal Title
  
  Tetrahedron 64
  
  Pages: 10810-10813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Absolute stereochemistry of amphidinolide Q2008
- Author(s)
  Takahashi, Y.; Kubota, T.; Fukushi, E.; Kawabata, J.; Kobayashi, J.
- Journal Title
  
  Org. Lett.
  
  Volume: 10 Issue: 17 Pages: 3709-3711
- DOI
  10.1021/ol8013123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Xestosaprol C, a new pentacyclic hydroquinone sulfate from a marine sponge Xestospongia sapra2008
- Author(s)
  Kubota, T.
- Journal Title
  
  Heterocycles 76
  
  Pages: 1571-1575
- NAID
  40016323251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Nakijiquinones G-I, new sesquiterpenoid quinones from marine sponge2008
- Author(s)
  Takahashi, Y.; Kubota, T.; Ito, J.; Mikami, Y.; Kobayashi, J.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 16 Issue: 16 Pages: 7561-7564
- DOI
  10.1016/j.bmc.2008.07.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Xestosaprol C, a new pentacyclic hydroquinone sulfate from a arine sponge Xestospongia sapra2008
- Author(s)
  Kubota, T.; Kon, Y.; Kobayashi, J.
- Journal Title
  
  Heterocycles
  
  Volume: 76 Issue: 2 Pages: 1571-1575
- DOI
  10.3987/com-08-s(n)122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Nagelamides M and N, new bromopyrrole alkaloids from sponge Agelas speices2008
- Author(s)
  Kubota, T.; Araki, A.; Ito, J.; Mikami, Y.; Fromont, J.; Kobayashi, J.
- Journal Title
  
  Tetrahedron
  
  Volume: 64 Issue: 48 Pages: 10810-10813
- DOI
  10.1016/j.tet.2008.09.039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390001
[Journal Article] Amphidinin B, a new polyketide metabolite from marine dinoflagellate Amphidinium sp.2006
- Author(s)
  Kubota, T.
- Journal Title
  
  J. Antibiot. 59 (8)
  
  Pages: 512-516
- NAID
  10018040527
- Data Source
  KAKENHI-PROJECT-18032005
[Journal Article] Amphidinolide C2, new macrolide from marine dinoflagellate Amphidinium sp.2004
- Author(s)
  Kubota, T
- Journal Title
  
  Marine Drugs 2(3)
  
  Pages: 83-87
- Data Source
  KAKENHI-PROJECT-16651104
[Presentation] 沖縄産海綿Suberea sp.から単離した新規ブロモチロシンアルカロイドの構造2022
- Author(s)
  栗本慎一郎、岡本彩乃、清野皐月、小林淳一、久保田高明
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07116
[Presentation] 沖縄産Dysidea属海綿から単離したポリヒドロキシステロールの構造および活性2021
- Author(s)
  栗本慎一郎、石塚芽衣菜、武田郁恵、矢口貴志、小林淳一、久保田高明
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20K07116
[Presentation] 能登産海藻Sargassum macrocarpumより単離した新規メロテルペノイド化合物の構造とAGEs生成阻害活性評価2021
- Author(s)
  篠田清哉、丹羽裕美、栗本慎一郎、久保田高明、関口光広
- Organizer
  日本生薬学会第67回年会
- Data Source
  KAKENHI-PROJECT-20K07116
[Presentation] 沖縄産Halichondria属海綿から単離した新規ステロイドの構造2020
- Author(s)
  森光希、栗本慎一郎、小林淳一、久保田高明
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K08345
[Presentation] 沖縄産Agelas属海綿から単離した新規ジテルペンアルカロイドの構造2020
- Author(s)
  近藤和幸、栗本慎一郎、小林淳一、久保田高明
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K08345
[Presentation] 沖縄産Amphimedon属海綿から単離した新規マンザミン関連アルカロイドの構造2020
- Author(s)
  栗本慎一郎、鈴木祥一、上野真由美、小林淳一、久保田高明
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K08345
[Presentation] 沖縄産Verongida目海綿から単離した新規ブロチロシンアルカロイドCeratinadin類およびMa'edamine類の構造2020
- Author(s)
  久保田高明、栗本慎一郎、大野泰斗、清野皐月、穗苅玲、石山亜紀、岩月正人、大村智、小林淳一
- Organizer
  第62回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-20K07116
[Presentation] 沖縄産Spongiidae科海綿から単離したセスキテルペノイドキノンの構造2020
- Author(s)
  猪俣実加、小川実華、栗本慎一郎、小林淳一、久保田高明
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K08345
[Presentation] 食用菊『阿房宮』に含まれる抗糖化活性物質の探索2020
- Author(s)
  水野実穂、栗本慎一郎、中村隆典、久保田高明
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K08345
[Presentation] 構造活性相関研究に向けたセスキテルペノイドキノン誘導体の調製2020
- Author(s)
  島田祐莉奈、小川実華、栗本慎一郎、小林淳一、久保田高明
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K08345
[Presentation] 食用菊「上大野」から単離した新規ポリアセチレン配糖体の構造2019
- Author(s)
  藤田浩輝、栗本慎一郎、川口恵未、中村隆典、佐々木有、久保田高明
- Organizer
  日本生薬学会第66回年会
- Data Source
  KAKENHI-PROJECT-17K08345
[Presentation] シソ科植物Teucrium chamaedrysから単離した新規ジテルペンの構造2019
- Author(s)
  若林宏治、栗本慎一郎、中村隆典、久保田高明
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K08345
[Presentation] 食用菊『上大野』から単離した新規ポリアセチレン配糖体の構造2019
- Author(s)
  藤田浩輝、栗本慎一郎、中村隆典、久保田高明
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K08345
[Presentation] 渦鞭毛藻Symbiodinium sp.から単離した新規マクロリドの構造2019
- Author(s)
  石田理紗、栗本慎一郎、小林淳一、久保田高明
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K08345
[Presentation] 沖縄産Hyrtios属海綿から単離した新規β－カルボリンアルカロイドの構造2018
- Author(s)
  髙橋秀彰、栗本慎一郎、小林淳一、久保田高明
- Organizer
  第22回天然薬物の開発と応用シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08345
[Presentation] 沖縄産Hyrtios属海綿から単離した新規インドールアルカロイドの構造2018
- Author(s)
  髙橋秀彰、栗本慎一郎、小林淳一、久保田高明
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K08345
[Presentation] 沖縄産Dysidea属海綿から単離した新規ポリヒドロキシステロールの構造2018
- Author(s)
  武田郁恵、栗本慎一郎、小林淳一、久保田高明
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K08345
[Presentation] 新品種の食用菊『上大野』花部の機能性に関する研究2018
- Author(s)
  中村隆典、栗本慎一郎、川口恵未、久保田高明、佐々木有
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K08345
[Presentation] 沖縄産Hyrtios属海綿から単離した新規Canthin-6-oneアルカロイドの構造2018
- Author(s)
  髙橋秀彰、栗本慎一郎、小林淳一、久保田高明
- Organizer
  日本生薬学会第65回年会
- Data Source
  KAKENHI-PROJECT-17K08345
[Presentation] 沖縄産Pseudoceratina属海綿から単離した新規ブロモチロシンアルカロイドの構造2018
- Author(s)
  大野泰斗、栗本慎一郎、小林淳一、久保田高明
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K08345
[Presentation] Zamamidine D, a new manzamine alkaloid from an Okinawan marine sponge Amphimedon sp.2017
- Author(s)
  Takaaki Kubota, Shin-ichiro Kurimoto, Kenta Nakamura, Kanae Sakai, Rei Hokari, Aki Ishiyama, Masato Iwatsuki, Kazuhiko Otoguro, Tohru Gonoi, Satoshi Omura, Jun’ichi Kobayashi
- Organizer
  America Society of Pharmacognosy 2017 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08345
[Presentation] Amphimedon属海綿から単離した新規マンザミンアルカロイドZamamiphidin AおよびZamamidine D2017
- Author(s)
  久保田高明、栗本慎一郎、上條優樹、中村健太、酒井香奈江、髙橋梓、穗苅玲、石山亜紀、岩月正人、乙黒一彦、五ノ井透、大村智、小林淳一
- Organizer
  第59回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-17K08345
[Presentation] 沖縄産 Plakortis 属海綿から単離した新規オキシリピンの構造2015
- Author(s)
  田中直伸、浅井美貴、草間大志、石黒悠一朗、久保田高明、小林淳一
- Organizer
  第57回天然有機化合物討論会
- Place of Presentation
  神奈川県横浜市、神奈川県民ホール
- Year and Date
  2015-09-09
- Data Source
  KAKENHI-PROJECT-25460115
[Presentation] 渦鞭毛藻ポリケチドのケミカルバイオロジー2015
- Author(s)
  久保田高明
- Organizer
  第17回マリンバイオテクノロジー学会大会
- Place of Presentation
  東京都品川区、東京海洋大学品川キャンパス
- Year and Date
  2015-05-30
- Invited
- Data Source
  KAKENHI-PROJECT-25460115
[Presentation] 沖縄産Spongiidae科海綿由来の新規メロテルペノイドNakijiquinone SおよびNakijinol Cの構造2015
- Author(s)
  久保田高明、鈴木春菜、髙橋梓、五ノ井透、小林淳一
- Organizer
  日本薬学会第135年会
- Place of Presentation
  兵庫県神戸市、デザインクリエイティブセンター
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25670043
[Presentation] 沖縄産Spongiidae科海綿由来の新規メロテルペノイドNakijiquinone SおよびNakijinol Cの構造2015
- Author(s)
  久保田高明、鈴木春菜、髙橋梓、五ノ井透、小林淳一
- Organizer
  日本薬学会第135年会
- Place of Presentation
  兵庫県神戸市、デザイン・クリエイティブセンター神戸
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25460115
[Presentation] 沖縄産Verongida目海綿より単離した新規アルカロイドの構造2015
- Author(s)
  久保田高明、渡瀬慎也、酒井香奈江、五ノ井透、小林淳一
- Organizer
  日本生薬学会第62回年会
- Place of Presentation
  岐阜県岐阜市、長良川国際会議場
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-25460115
[Presentation] New polyketides from dinoflagellate Amphidinium sp.2015
- Author(s)
  Takaaki Kubota, Takahiro Iwai, Hayato Sato, Jun'ichi Kobayashi
- Organizer
  The 2015 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460115
[Presentation] 沖縄産Agelas属海綿由来の新規二量体型ブロモピロールアルカロイドの構造2014
- Author(s)
  久保田高明、岩井隆宏、小林淳一
- Organizer
  日本生薬学会第61回年会
- Place of Presentation
  福岡県福岡市、福岡大学薬学部
- Year and Date
  2014-09-13
- Data Source
  KAKENHI-PROJECT-25460115
[Presentation] 海洋生物を素材とした抗真菌剤の開発2014
- Author(s)
  久保田高明
- Organizer
  東京大学医科学研究所－千葉大学真菌医学研究センター合同成果発表会
- Place of Presentation
  東京都港区、東京大学医科学研究所講堂
- Data Source
  KAKENHI-PROJECT-25460115
[Presentation] 沖縄産Spongiidae科海綿より単離した新規アセチレン脂肪酸誘導体taurospongin BおよびCの構造2014
- Author(s)
  久保田高明、鈴木春菜、小林淳一
- Organizer
  第20回天然薬物の開発と応用シンポジウム
- Place of Presentation
  東京都文京区、東京大学弥生講堂
- Year and Date
  2014-11-06
- Data Source
  KAKENHI-PROJECT-25670043
[Presentation] 沖縄産Amphimedon属海綿由来の新規マンザミン関連アルカロイドZamamiphidin Aの構造2014
- Author(s)
  久保田高明、上條優樹、髙橋梓、五ノ井透、小林淳一
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本県熊本市、熊本市総合体育館
- Data Source
  KAKENHI-PROJECT-25670043
[Presentation] 沖縄産Agelas属海綿由来の新規二量体型ブロモピロールアルカロイドの構造2014
- Author(s)
  久保田高明、岩井隆宏、小林淳一
- Organizer
  日本生薬学会第61回年会
- Place of Presentation
  福岡県福岡市、福岡大学薬学部
- Year and Date
  2014-09-13
- Data Source
  KAKENHI-PROJECT-25670043
[Presentation] 沖縄産Amphimedon属海綿由来の新規マンザミン関連アルカロイドzamamiphidin Aの構造2014
- Author(s)
  久保田高明、上條優樹、髙橋梓、五ノ井透、小林淳一
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本県熊本市、熊本市総合体育館
- Data Source
  KAKENHI-PROJECT-25460115
[Presentation] 海洋共生微生物が生産する特異な構造を有する天然物の探索2014
- Author(s)
  久保田高明
- Organizer
  北大の研究者がつむぐ微生物の世界
- Place of Presentation
  北海道札幌市、北海道大学農学部大講堂
- Invited
- Data Source
  KAKENHI-PROJECT-25460115
[Presentation] Amphidinium属渦鞭毛藻より単離した新規ポリケチドの構造2014
- Author(s)
  久保田高明、岩井隆宏、小林淳一
- Organizer
  第56回天然有機化合物討論会
- Place of Presentation
  高知県高知市、高知県立県民文化ホール、三翠園
- Year and Date
  2014-10-15
- Data Source
  KAKENHI-PROJECT-25460115
[Presentation] 沖縄産Spongiidae科海綿より単離した新規アセチレン脂肪酸誘導体taurospongin BおよびCの構造2014
- Author(s)
  久保田高明、鈴木春菜、小林淳一
- Organizer
  第20回天然薬物の開発と応用シンポジウム
- Place of Presentation
  東京都文京区、東京大学弥生講堂
- Year and Date
  2014-11-06
- Data Source
  KAKENHI-PROJECT-25460115
[Presentation] Amphidinium属渦鞭毛藻より単離した新規ポリケチドの構造2014
- Author(s)
  久保田高明、岩井隆宏、小林淳一
- Organizer
  第56回天然有機化合物討論会
- Place of Presentation
  高知県高知市、高知県立県民文化ホール、三翠園
- Year and Date
  2014-10-15
- Data Source
  KAKENHI-PROJECT-25670043
[Presentation] 沖縄産Plakortis属海綿由来の新規ポリケタイドManzamenone L-Nの構造2013
- Author(s)
  久保田高明、石黒悠一朗、髙橋梓、五ノ井透、小林淳一
- Organizer
  日本生薬学会第60年会
- Place of Presentation
  北海道当別町、北海道医療大学当別キャンパス中央講義棟
- Data Source
  KAKENHI-PROJECT-25670043
[Presentation] 沖縄産Plakortis属海綿由来の新規ポリケタイドManzamenone L-Nの構造2013
- Author(s)
  久保田高明、石黒悠一朗、髙橋梓、五ノ井透、小林淳一
- Organizer
  日本生薬学会第60年会
- Place of Presentation
  北海道当別町、北海道医療大学当別キャンパス中央講義棟
- Data Source
  KAKENHI-PROJECT-25460115
[Presentation] 沖縄産ホヤEudistoma glaucus由来の新規・-カルボリンアルカロイドEudistomidin H-Kの構造2012
- Author(s)
  久保田高明
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-20390001
[Presentation] 沖縄産ホヤEudistoma glaucus由来の新規β-カルボリンアルカロイドEudistomidinH-Kの構造2012
- Author(s)
  久保田高明(小林淳一)
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-20390001
[Presentation] Biosynthetic study of amphidinolides2012
- Author(s)
  久保田高明
- Organizer
  International Conference of Natural Products Biosynthesis
- Place of Presentation
  淡路夢舞台国際会議場（淡路島）
- Year and Date
  2012-06-17
- Data Source
  KAKENHI-PUBLICLY-23108502
[Presentation] 渦鞭毛藻由来マクロリドの特異な生合成経路の解明2012
- Author(s)
  久保田高明
- Organizer
  新学術領域研究「生合成マシナリー：生物活性物質構造多様性創出システムの解明と制御」第4回公開シンポジウム
- Place of Presentation
  東京大学弥生講堂（東京都文京区）
- Year and Date
  2012-12-07
- Data Source
  KAKENHI-PUBLICLY-23108502
[Presentation] 沖縄産Plakortis属海綿由来の新規ポリケタイドUntenolide Aの構造2011
- Author(s)
  久保田高明(小林淳一)
- Organizer
  日本薬学会第131年会
- Place of Presentation
  ツインメッセ静岡(静岡県)
- Year and Date
  2011-03-31
- Data Source
  KAKENHI-PROJECT-20390001
[Presentation] 渦鞭毛藻由来マクロリドの特異な生合成経路の解明2011
- Author(s)
  久保田高明
- Organizer
  「生合成マシナリー」第2回若手シンポジウム
- Place of Presentation
  理化学研究所鈴木梅太郎ホール(埼玉県)(招待講演)
- Year and Date
  2011-06-25
- Data Source
  KAKENHI-PUBLICLY-23108502
[Presentation] 特異な構造を有する天然物の探索ならびに生合成研究2011
- Author(s)
  久保田高明
- Organizer
  若手研究者のための有機化学札幌セミナー2011
- Place of Presentation
  北海道大学大学院農学研究院(札幌市)(招待講演)
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-20390001
[Presentation] 渦鞭毛藻由来マクロリドの特異な生合成経路の解明2011
- Author(s)
  久保田高明
- Organizer
  「生合成マシナリー:生物活性物質構造多様性創出システムの解明と制御」第2回公開シンポジウム
- Place of Presentation
  東京大学(東京都文京区)
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PUBLICLY-23108502
[Presentation] 特異な構造を有する天然物の探索ならびに生合成研究2011
- Author(s)
  久保田高明
- Organizer
  若手研究者のための有機化学札幌セミナー2011
- Place of Presentation
  北海道大学(札幌市)(招待講演)
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PUBLICLY-23108502
[Presentation] 渦鞭毛藻由来マクロリドの特異な生合成経路の解明2011
- Author(s)
  久保田高明
- Organizer
  「生合成マシナリー:生物活性物質構造多様性創出システムの解明と制御」第3回公開シンポジウム
- Place of Presentation
  東京大学(東京都文京区)
- Year and Date
  2011-12-03
- Data Source
  KAKENHI-PUBLICLY-23108502
[Presentation] 特異な構造を有する天然物の探索ならびに生合成研究2011
- Author(s)
  久保田高明(小林淳一)
- Organizer
  若手研究者のための有機化学札幌セミナー2011(招待講演)
- Place of Presentation
  北海道大学大学院農学研究院(札幌市)
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-20390001
[Presentation] 沖縄産海綿由来の新規ピリジニウムアルカロイドplatisidine A～Cの構造2010
- Author(s)
  久保田高明
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山県総合グラウンド体育館、岡山市
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20390001
[Presentation] 沖縄産海綿由来の新規ブロモチロシンアルカロイドCeratinadin A-Cの構造2010
- Author(s)
  久保田高明(小林淳一)
- Organizer
  日本生薬学会第57回年会
- Place of Presentation
  パークウエストンホテル & ウエディング(徳島県)
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-20390001
[Presentation] 沖縄産海綿由来の新規ブロモチロシンアルカロイドCeratinadin A-Cの構造2010
- Author(s)
  久保田高明
- Organizer
  日本生薬学会第57回年会
- Place of Presentation
  パークウエストンホテル&ウエディング(徳島県)
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-20390001
[Presentation] 沖縄産海綿由来の新規ブロモチロシンアルカロイドTyrokeradine AおよびBの構造2009
- Author(s)
  久保田高明(小林淳一)
- Organizer
  日本薬学会第129年会
- Place of Presentation
  国立京都国際会館(京都府)
- Data Source
  KAKENHI-PROJECT-20390001
[Presentation] 沖縄産海綿由来の新規ブロモチロシンアルカロイド Tyrokeradine AおよびBの構造2009
- Author(s)
  久保田高明
- Organizer
  日本薬学会第129年会
- Place of Presentation
  国立京都国際会館、京都
- Data Source
  KAKENHI-PROJECT-20390001
[Presentation] Structures and activities of new terpenoid quinones from Okinawan sponges2008
- Author(s)
  久保田高明
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場、名古屋
- Data Source
  KAKENHI-PROJECT-20390001
[Presentation] 沖縄産海綿より単離した新規テルペノイドキノン類の構造と活性2008
- Author(s)
  久保田高明
- Organizer
  第12回日本がん分子標的治療研究会総会
- Place of Presentation
  学術総合センター、東京
- Data Source
  KAKENHI-PROJECT-20390001
[Presentation] 沖縄産海綿より単離した新規テルペノイドキノン類の構造と活性2008
- Author(s)
  久保田高明(小林淳一)
- Organizer
  第12回日本がん分子標的治療研究会総会
- Place of Presentation
  学術総合センター(東京都)
- Data Source
  KAKENHI-PROJECT-20390001
[Presentation] Structures and activities of new terpenoid quinones from Okinawan sponges2008
- Author(s)
  久保田高明(小林淳一)
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場、(愛知県)
- Data Source
  KAKENHI-PROJECT-20390001

1. KOBAYASHI Jun'ichi (90221241)

# of Collaborated Projects: 8 results

# of Collaborated Products: 54 results
2. ISHIYAMA Haruaki (70333622)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
3. TSUDA Masashi (10261322)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. KATAKURA Ken (10130155)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. GONOI Tohru (30134365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
6. TANAKA Naonobu (40455598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 笹木敬司 (00183822)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 山本隆晴 (80312346)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 森田博史 (70220069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 將口栄一 (90378563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 濱田麻友子 (40378584)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 竹内猛 (60599231)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 栗本慎一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Kubota Takaaki 久保田 高明

KUBOTA Takaaki 久保田 高明

久保田 高明 クボタ タカアキ

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Development of nuclear receptor PXR antagonists from marine natural productsPrincipal Investigator

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Development of new anti-infective drugs from dinoflagellatePrincipal Investigator

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Development of new antitrypanosomal drugs from marine alkaloidsPrincipal Investigator

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渦鞭毛藻由来マクロリドの特異な生合成経路の解明Principal Investigator

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渦鞭毛藻由来マクロリドamphidinolide Cの立体化学と生合成経路の解明Principal Investigator

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Kubota Takaaki 久保田高明

KUBOTA Takaaki 久保田高明

久保田高明クボタタカアキ