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Mamura Mizuko  真村 瑞子

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真村 瑞子  マムラ ミズコ

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Researcher Number 60400686
Affiliation (Current) 2025: 東京医科大学, 医学部, 兼任教授
Affiliation (based on the past Project Information) *help 2022 – 2023: 東京医科大学, 医学部, 兼任教授
2018 – 2020: 東京医科大学, 医学部, 兼任教授
2016 – 2017: 東京医科大学, 医学部, 教授
Review Section/Research Field
Principal Investigator
Collagenous pathology/Allergology
Except Principal Investigator
Basic Section 53050:Dermatology-related / Basic Section 55040:Respiratory surgery-related
Keywords
Principal Investigator
細胞・組織 / シグナル伝達 / 免疫学 / STAT / SMAD / TGF-beta / Th17細胞 / STAT3 / Smad3/4 / Stat … More / IL-6 / Smad / TGF-β / Th17 / 関節リウマチ … More
Except Principal Investigator
SMAD / TGF-β / 生物学的治療薬 / ランゲルハンス細胞 / 樹状細胞 / TGF-βシグナル伝達機構 / 尋常性乾癬 / T細胞 / 乾癬 / EGFR-TKI耐性 / 肺癌 / リンカー / Smad2 / 上皮成長因子受容体-チロシンキナーゼ阻害薬抵抗性 / SMADリン酸化 / 非小細胞性肺癌 / SMADリン酸化 / リンカーリン酸化 / IL-6 / EGFR-TKI抵抗性 / 非小細胞肺癌 Less
  • Research Projects

    (3 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (12 People)
  •  乾癬の病態形成におけるTGF-βシグナルの役割

    • Principal Investigator
      大久保 ゆかり
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Tokyo Medical University
  •  Linker-phosphorylated SMAD2 induces resistance to tyrosine kinase inhibition in EGFR-mutated lung adenocarcinoma

    • Principal Investigator
      Makino Yojiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Tokyo Medical University
  •  SMAD-STAT signaling network in the pathogenesis of rheumatoid arthritisPrincipal Investigator

    • Principal Investigator
      Mamura Mizuko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      Tokyo Medical University

All 2023 2022 2018 2017 2016

All Presentation

  • [Presentation] Canonical TGF-β signaling via SMAD3 and SMAD4 ameliorates psoriasis by suppressing Th1 and Th17 differentiation2023

    • Author(s)
      Jeong-Hwan Yoon, Eunjin Bae, Jin Soo Han, In-Kyu Lee, Ji Hyeon Ju, Masahiko Kuroda, Yukari Okubo and Mizuko Mamura
    • Organizer
      第38回日本乾癬学会学術大会
    • Data Source
      KAKENHI-PROJECT-22K08415
  • [Presentation] Canonical TGF-β signaling via SMAD3 and SMAD4 suppresses Th1 and Th17 differentiation in the pathogenesis of psoriasis2022

    • Author(s)
      Mizuko Mamura, Jeong-Hwan Yoon, Eunjin Bae, Inkyu Lee, Jin Soo Han, Ji-Hyun Ju, Masahiko Kuroda, Yukari Okubo, Isao Matsumoto, Takayuki Sumida
    • Organizer
      第66回日本リウマチ学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-22K08415
  • [Presentation] CD4+ T cell-intrinsic SMAD4 is essential for Th2 differentiation in Th2-type allergic dermatitis2022

    • Author(s)
      Mizuko Mamura, Eunjin Bae, Jin Soo Han, In-Kyu Lee, Ji Hyeon Ju, Yukari Okubo, Jeong-Hwan Yoon
    • Organizer
      第71回日本アレルギー学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K08415
  • [Presentation] Canonical TGF-β signaling via Smad3/4 suppresses Th17 differentiation2018

    • Author(s)
      Jeong-Hwan Yoon, Eunjin Bae, Ji Hyeon Ju, In-Kyu Lee, Isao Matsumoto, Takayuki Sumida, Mizuko Mamura
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09908
  • [Presentation] Canonical TGF-β signaling via SMAD3 and SMAD4 suppresses STAT3-induced arthritogenic Th17 differentiation2018

    • Author(s)
      Jeong-Hwan Yoon, Eunjin Bae, Ji Hyeon Ju, Masahiro Yokosawa, Yuya Kondo, Isao Matsumoto, Takayuki Sumida, Mizuko Mamura
    • Organizer
      第5回 日本リウマチ学会ベーシックリサーチカンファレンス
    • Data Source
      KAKENHI-PROJECT-16K09908
  • [Presentation] Canonical TGF-β signaling via C-terminally phosphorylated Smad3 and Smad4 suppresses Th17 differentiation2018

    • Author(s)
      真村瑞子
    • Organizer
      第62回日本リウマチ学会総会・学術集会International Concurrent Workshop3: Immunology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09908
  • [Presentation] Canonical SMADシグナルとnon-canonical SMADシグナルによる免疫細胞分化制御2017

    • Author(s)
      真村瑞子
    • Organizer
      2017年度生命科学系学会合同年次大会(ConBio2017)ワークショップ: Smadシグナルのcanonical経路とnon-canonical経路
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09908
  • [Presentation] 関節炎でのTh17分化2017

    • Author(s)
      真村瑞子
    • Organizer
      第38回日本炎症・再生医学会シンポジウム13骨・軟骨の炎症と再生(骨免疫学会合同)
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09908
  • [Presentation] Canonical TGF-β signaling via Smad3/4 regulates expression and function of SOCS3 to suppress Th17 differentiation2016

    • Author(s)
      Mizuko Mamura, Jeong-Hwan Yoon, Ji Hyeon Ju, Isao Matsumoto, Takayuki Sumida
    • Organizer
      The 60th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2016-04-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09908
  • 1.  尹 晶煥 (30748885)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 2.  裴 恩真 (40773388)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 3.  Makino Yojiro (70421047)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  住田 孝之 (00183054)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 5.  大平 達夫 (40317847)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  池田 徳彦 (70246205)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  大久保 ゆかり (40233530)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 8.  神田 浩子 (00345208)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  KATO Mitsuyasu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  SUDO Katsuko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  MIYAZAWA Keiji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  KURODA Masahiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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