Murata Yoji 村田陽二

… Alternative Names

MURATA Yoji 村田陽二

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Researcher Number	60400735
Other IDs
Affiliation (Current)	2025: 神戸大学, 医学研究科, 准教授
Affiliation (based on the past Project Information) *help	2025: 神戸大学, 医学研究科, 准教授 2016 – 2023: 神戸大学, 医学研究科, 准教授 2016: 神戸大学, 大学院医学研究科, 准教授 2012 – 2015: 神戸大学, 医学(系)研究科(研究院), 准教授 2012 – 2013: 神戸大学, 医学研究科, 准教授 … More 2010 – 2011: 神戸大学, 医学研究科, 助教 2007 – 2009: Gunma University, 生体調節研究所, 助教 2007: 群馬大, 生体調節研究所, 助手 2005 – 2006: 群馬大学, 生体調節研究所, 助手 Less
Review Section/Research Field	Principal Investigator General medical chemistry / Basic Section 49010:Pathological biochemistry-related / Pathological medical chemistry Except Principal Investigator Functional biochemistry / Biological Sciences
Keywords	Principal Investigator チロシンホスファターゼ / 自然免疫系細胞 / 細胞間シグナル / がん微小環境 / がん / 腸炎 / 腸管免疫 / 腸上皮細胞 / 腫瘍免疫制御 / がん細胞 … More / 免疫チェックポイント / 膜型分子 / マクロファージ / がん免疫監視 / 腸内細菌 / 大腸がん / 炎症性腸疾患 / チロシンホスタファーゼ / 抗菌ペプチド / IL-10 / SAP-1 / チロシンキナーゼ / サイトカイン / 免疫応答 / 上皮細胞 / 大腸炎 / ケモカイン / 腸粘膜上皮細胞 / SAP1 / 受容体型チロシンホスファターゼ / アピカル / 上皮系細胞 / MR-GEF / PDZ-GEF / Rap1 / GTP交換因子 / GDP / 低分子量G蛋白質 / 神経軸索 / 極性細胞 / 神経細胞 … More Except Principal Investigator 生体分子 / シグナル伝達 / 免疫学 / 脳・神経 / 癌 / 蛋白質 / Cdc42 / Rac / SAP-1 / がん / 樹状細胞 / NKT細胞 / SHPS-1 / CD47 / 細胞接着 / 細胞増殖 / 酵素 Less

がん微小環境でのがん免疫監視における自然免疫細胞の機能的役割とその作用機構の解明Principal Investigator
- Principal Investigator
  
  村田陽二
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kobe University
がん微小環境における細胞間シグナルによる腫瘍免疫制御Principal Investigator
- Principal Investigator
  
  村田陽二
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kobe University
Molecular mechanisms underlying an immune evasion by cancer cells via cell-to-cell signalingPrincipal Investigator
- Principal Investigator
  
  Murata Yoji
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kobe University
Regulation of intestinal immunity by an intestinal epithelial-specific protein tyrosine phosphatasePrincipal Investigator
- Principal Investigator
  
  Murata Yoji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kobe University
Molecular basis of the CD47-SIRP alpha signaling system in the regulation of physiological function
- Principal Investigator
  
  Matozaki Takashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kobe University
Regulation of intestinal immunity by a gastrointestinal epithelial-specific protein tyrosine phosphatase and its pathological role.Principal Investigator
- Principal Investigator
  
  Murata Yoji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kobe University
The integrative research for regulation by protein tyrosine phosphatases of biological functions and its molecular mechanism
- Principal Investigator
  
  MATOZAKI Takashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kobe University
Role of SAP-1,a gastrointestinal-specific protein tyrosine phosphatasePrincipal Investigator
- Principal Investigator
  
  MURATA Yoji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kobe University
Molecular mechanism underlying the apical sorting of membrane proteins in epithelial cellsPrincipal Investigator
- Principal Investigator
  
  MURATA Yoji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Gunma University
神経細胞の極性形成におけるRap1の作用機構と生理機能Principal Investigator
- Principal Investigator
  
  村田陽二
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  General medical chemistry
- Research Institution
  Gunma University
Protein tyrosine phosphatases and regulation of cancer cell adhesion/migration
- Principal Investigator
  
  MATOZAKI Takashi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University

[Journal Article] Preclinical evaluation of the efficacy of an antibody to human SIRPα for cancer immunotherapy in humanized mouse models2023
- Author(s)
  Saito Yasuyuki、Iida-Norita Rie、Afroj Tania、Refaat Alaa、Hazama Daisuke、Komori Satomi、Ohata Shinya、Takai Tomoko、Oduori Okechi S.、Kotani Takenori、Funakoshi Yohei、Koma Yu-Ichiro、Murata Yoji、Yakushijin Kimikazu、Matsuoka Hiroshi、Minami Hironobu、Yokozaki Hiroshi、Manz Markus G.、Matozaki Takashi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 14 Pages: 1294814-1294814
- DOI
  10.3389/fimmu.2023.1294814
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06926, KAKENHI-PROJECT-22K08504, KAKENHI-PROJECT-22K19458, KAKENHI-PROJECT-22K15494, KAKENHI-PROJECT-22K16302, KAKENHI-PROJECT-22KF0254, KAKENHI-PROJECT-21H04807
[Journal Article] CD47 promotes peripheral T cell survival by preventing dendritic cell?mediated T cell necroptosis2023
- Author(s)
  Komori Satomi、Saito Yasuyuki、Nishimura Taichi、Respatika Datu、Endoh Hiromi、Yoshida Hiroki、Sugihara Risa、Iida-Norita Rie、Afroj Tania、Takai Tomoko、Oduori Okechi S.、Nitta Eriko、Kotani Takenori、Murata Yoji、Kaneko Yoriaki、Nitta Ryo、Ohnishi Hiroshi、Matozaki Takashi
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 33 Pages: 1-1
- DOI
  10.1073/pnas.2304943120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06926, KAKENHI-PROJECT-22K08504, KAKENHI-PROJECT-21K08416, KAKENHI-PROJECT-22K19458, KAKENHI-PROJECT-22K15494, KAKENHI-PROJECT-22K16302, KAKENHI-PROJECT-22KF0254, KAKENHI-PLANNED-21H05254, KAKENHI-PROJECT-21H04807, KAKENHI-PROJECT-23K24057
[Journal Article] Targeting of SIRPα as a potential therapy for Langerhans cell histiocytosis2023
- Author(s)
  Okamoto Takeshi、Murata Yoji、Hasegawa Daiichiro、Yoshida Makiko、Tanaka Daisuke、Ueda Takashi、Hazama Daisuke、Oduori Okechi S.、Komori Satomi、Takai Tomoko、Saito Yasuyuki、Kotani Takenori、Kosaka Yoshiyuki、Maniwa Yoshimasa、Matozaki Takashi
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 5 Pages: 1871-1881
- DOI
  10.1111/cas.15758
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06926, KAKENHI-PROJECT-22KF0254, KAKENHI-PROJECT-22K08504, KAKENHI-PROJECT-22K19458, KAKENHI-PROJECT-22K15494, KAKENHI-PROJECT-21H04807
[Journal Article] The Role of Type-2 Conventional Dendritic Cells in the Regulation of Tumor Immunity2022
- Author(s)
  Saito Yasuyuki、Komori Satomi、Kotani Takenori、Murata Yoji、Matozaki Takashi
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 8 Pages: 1976-1976
- DOI
  10.3390/cancers14081976
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06926, KAKENHI-PROJECT-22K08504, KAKENHI-PROJECT-22K19458, KAKENHI-PROJECT-22K15494, KAKENHI-PROJECT-21H04807
[Journal Article] Anticancer efficacy of monotherapy with antibodies to SIRPα/SIRPβ1 mediated by induction of antitumorigenic macrophages2021
- Author(s)
  Sakamoto Mariko、Murata Yoji、Tanaka Daisuke、Kakuchi Yuka、Okamoto Takeshi、Hazama Daisuke、Saito Yasuyuki、Kotani Takenori、Ohnishi Hiroshi、Miyasaka Masayuki、Fujisawa Masato、Matozaki Takashi
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 1
- DOI
  10.1073/pnas.2109923118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07385, KAKENHI-PROJECT-20K21547, KAKENHI-PROJECT-21H04807
[Journal Article] Macrocyclic Peptide-Mediated Blockade of the CD47-SIRPα Interaction as a Potential Cancer Immunotherapy2020
- Author(s)
  Hazama Daisuke、Yin Yizhen、Murata Yoji、Matsuda Makoto、Okamoto Takeshi、Tanaka Daisuke、Terasaka Naohiro、Zhao Jinxuan、Sakamoto Mariko、Kakuchi Yuka、Saito Yasuyuki、Kotani Takenori、Nishimura Yoshihiro、Nakagawa Atsushi、Suga Hiroaki、Matozaki Takashi
- Journal Title
  
  Cell Chemical Biology
  
  Volume: 27 Issue: 9 Pages: 1181-1191.e7
- DOI
  10.1016/j.chembiol.2020.06.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07385, KAKENHI-PROJECT-20K21547, KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-18H04032
[Journal Article] Blockade of CD47 or SIRPα: a new cancer immunotherapy2020
- Author(s)
  Murata Yoji、Saito Yasuyuki、Kotani Takenori、Matozaki Takashi
- Journal Title
  
  Expert Opinion on Therapeutic Targets
  
  Volume: 24 Issue: 10 Pages: 945-951
- DOI
  10.1080/14728222.2020.1811855
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07385, KAKENHI-PROJECT-20K21547, KAKENHI-PROJECT-18H04032
[Journal Article] Role of Csk in intestinal epithelial barrier function and protection against colitis2018
- Author(s)
  Sun Chunxiao、Murata Yoji、Imada Shinya、Konno Tasuku、Kotani Takenori、Saito Yasuyuki、Yamada Hideto、Matozaki Takashi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 504 Issue: 1 Pages: 109-114
- DOI
  10.1016/j.bbrc.2018.08.140
- NAID
  120006775950
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15190, KAKENHI-PROJECT-18H04032, KAKENHI-PROJECT-16K08586, KAKENHI-PROJECT-16K08624
[Journal Article] Microvillus-specific protein tyrosine phosphatase SAP-1 plays a role in regulating the intestinal paracellular transport of macromolecules.2017
- Author(s)
  Mori S, Kamei N, Murata Y, Takayama K, Matozaki T, Takeda-Morishita M.
- Journal Title
  
  J Pharm Sci.
  
  Volume: 106 Issue: 9 Pages: 2904-2908
- DOI
  10.1016/j.xphs.2017.04.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08624, KAKENHI-PROJECT-16K15219
[Journal Article] Anti-SIRPα antibodies as a potential new tool for cancer immunotherapy.2017
- Author(s)
  Yanagita T, Murata Y, Tanaka D, Motegi S, Arai E, Daniwijaya EW, Hazama D, Washio K, Saito Y, Kotani T, Ohnishi H, Oldenborg PA, Verjan Garcia N, Miyasaka M, Ishikawa O, Kanai Y, Komori T, Matozaki T.
- Journal Title
  
  JCI Insight
  
  Volume: 2 Issue: 1
- DOI
  10.1172/jci.insight.89140
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111005, KAKENHI-PROJECT-26291022, KAKENHI-PROJECT-26670110, KAKENHI-PROJECT-15K08532, KAKENHI-PROJECT-16K08720
[Journal Article] Future therapeutic potential of SAP-1 in inflammatory bowel diseases2016
- Author(s)
  Kotani T, Murata Y, Saito Y, Matozaki T.
- Journal Title
  
  Expert Rev Gastroenterol Hepatol.
  
  Volume: 10 Issue: 12 Pages: 1313-1315
- DOI
  10.1080/17474124.2016.1245144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08624, KAKENHI-PROJECT-16K15219
[Journal Article] Role of Src family kinases in regulation of intestinal epithelial homeostasis.2016
- Author(s)
  Imada S, Murata Y, Kotani T, Hatano M, Sun C, Konno T, Park JH, Kitamura Y, Saito Y, Ohdan H, Matozaki T.
- Journal Title
  
  Mol Cell Biol
  
  Volume: 36 Issue: 22 Pages: 2811-2823
- DOI
  10.1128/mcb.00311-16
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26291022, KAKENHI-PROJECT-16K08624, KAKENHI-PROJECT-16K15219
[Journal Article] Dendritic cell SIRPα regulates homeostasis of dendritic cells in lymphoid organs2015
- Author(s)
  Washio K, Kotani T, Saito Y, Respatika D, Murata Y, Kaneko Y, Okazawa H, Ohnishi H, Fukunaga A, Nishigori C, Matozaki T.
- Journal Title
  
  Genes Cells
  
  Volume: - Issue: 6 Pages: 00-00
- DOI
  10.1111/gtc.12238
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590380, KAKENHI-PUBLICLY-25112709, KAKENHI-PROJECT-25461468, KAKENHI-PROJECT-26291022, KAKENHI-PROJECT-26670142, KAKENHI-PROJECT-15K08532, KAKENHI-PROJECT-26860210
[Journal Article] Shp2 in forebrain neurons regulates synaptic plasticity, locomotion, and memory formation in mice2015
- Author(s)
  Kusakari S, Saitow F, Ago Y, Shibasaki K, Sato-Hashimoto, M., Matsuzaki, Y., Kotani T, Murata Y, Hirai H, Matsuda T, Suzuki H, Matozaki T, Ohnishi H
- Journal Title
  
  Mol. Cell. Biol.
  
  Volume: 35 Issue: 9 Pages: 1557-1572
- DOI
  10.1128/mcb.01339-14
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23500437, KAKENHI-PUBLICLY-25112709, KAKENHI-PROJECT-25430062, KAKENHI-PROJECT-25870110, KAKENHI-PROJECT-26291022, KAKENHI-PROJECT-26670142, KAKENHI-PROJECT-26670110, KAKENHI-PUBLICLY-26111703, KAKENHI-PROJECT-15H03000, KAKENHI-PUBLICLY-26111702, KAKENHI-PUBLICLY-26117502
[Journal Article] 【プロテインホスファターゼの最先端:制御機構から医療まで】受容体型チロシンホスファターゼの機能と病態　R3サブタイプチロシンホスファターゼを中心に(解説/特集)2015
- Author(s)
  村田陽二, 小谷武徳, 的崎尚
- Journal Title
  
  生化学
  
  Volume: 87 Pages: 547-553
- Data Source
  KAKENHI-PROJECT-25460366
[Journal Article] Regulation by gut commensal bacteria of carcinoembryonic antigen-related cell adhesion molecule expression in the intestinal epithelium2015
- Author(s)
  Kitamura Y, Murata Y, Park JH, Kotani T, Imada S, Saito Y, Okazawa H, Azuma T, Matozaki T.
- Journal Title
  
  Genes Cells.
  
  Volume: - Issue: 7 Pages: 578-589
- DOI
  10.1111/gtc.12247
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-25112709, KAKENHI-PROJECT-26670142, KAKENHI-PROJECT-25460366, KAKENHI-PROJECT-26291022
[Journal Article] Protein tyrosine phosphatase SAP-1 protects against colitis through regulation of CEACAM20 in the intestinal epithelium2015
- Author(s)
  Y Murata, T Kotani, Y Supriatna, Y Kitamura, S Imada, K Kawahara, M Nishio, EW Daniwijaya, H Sadakata, S Kusakari, M Mori, Y Kanazawa, Y Saito, K Okawa, M Takeda-Morishita, H Okazawa, H Ohnishi, T Azuma, A Suzuki, T Matozaki
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 112 Issue: 31
- DOI
  10.1073/pnas.1510167112
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08532, KAKENHI-PROJECT-26670160, KAKENHI-PROJECT-25460366, KAKENHI-PROJECT-26670142, KAKENHI-PROJECT-26291022
[Journal Article] Autoimmune animal models in the analysis of the CD47-SIRPα signaling pathway2014
- Author(s)
  Murata Y, Saito Y, Kaneko T, Kotani T, Kaneko Y, Ohnishi H, Matozaki T
- Journal Title
  
  Methods
  
  Volume: 65 Issue: 2 Pages: 254-9
- DOI
  10.1016/j.ymeth.2013.09.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370061, KAKENHI-PROJECT-23500437, KAKENHI-PUBLICLY-24111508, KAKENHI-PUBLICLY-25112709, KAKENHI-PROJECT-25460366, KAKENHI-PUBLICLY-26111703, KAKENHI-PROJECT-26670110
[Journal Article] The CD47-SIRPα signalling system : its physiological roles and therapeutic application2014
- Author(s)
  Murata Y, Kotani T, Ohnishi H, Matozaki T
- Journal Title
  
  J Biochem
  
  Volume: 155 Issue: 6 Pages: 335-344
- DOI
  10.1093/jb/mvu017
- NAID
  40020088978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370061, KAKENHI-PROJECT-23500437, KAKENHI-PUBLICLY-25112709, KAKENHI-PROJECT-25460366, KAKENHI-PUBLICLY-26111703, KAKENHI-PROJECT-26670110
[Journal Article] Role of the protein tyrosine phosphatase Shp2 in homeostasis of the intestinal epithelium2014
- Author(s)
  Yamashita H, Kotani T, Park JH, Murata Y, Okazawa H, Ohnishi H, Ku Y, Matozaki T
- Journal Title
  
  PLoSOne
  
  Volume: 9 Issue: 3 Pages: e92904-e92904
- DOI
  10.1371/journal.pone.0092904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370061, KAKENHI-PROJECT-24590380, KAKENHI-PUBLICLY-25112709, KAKENHI-PUBLICLY-25114709, KAKENHI-PROJECT-25460366
[Journal Article] Shear Stress-induced Redistribution of Vascular Endothelial-Protein-tyrosine Phosphatase (VE-PTP) in Endothelial Cells and Its Role in Cell Elongation2014
- Author(s)
  Mantilidewi KI, Murata Y, Mori M, Otsubo C, Kotani T, Kusakari S, Ohnishi H, Matozaki T
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Issue: 10 Pages: 6451-61
- DOI
  10.1074/jbc.m113.529503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370061, KAKENHI-PUBLICLY-25112709, KAKENHI-PROJECT-25460366
[Journal Article] Hypothermia-dependent and -independent effects of forced swim on the phosphorylation states of signaling molecules in mouse hippocampus.2012
- Author(s)
  Hayashi Y
- Journal Title
  
  Biochemical and biophysical research communications.
  
  Volume: 428 Issue: 4 Pages: 475-481
- DOI
  10.1016/j.bbrc.2012.10.083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590265, KAKENHI-PROJECT-23370061, KAKENHI-PROJECT-23500437, KAKENHI-PROJECT-23659155, KAKENHI-PROJECT-23700438, KAKENHI-PROJECT-23790353, KAKENHI-PUBLICLY-23112509, KAKENHI-PUBLICLY-24111508
[Journal Article] Hypothermia-induced tyrosine phosphorylation of SIRPα in the brain2012
- Author(s)
  Maruyama T., Kusakari S., Sato-Hashimoto M., Hayashi Y., Kotani T., Murata Y., Okazawa H., Oldenborg P.-A., Kishi S., Matozaki T., and Ohnishi H.
- Journal Title
  
  J. Neurochem
  
  Volume: 121 Issue: 6 Pages: 891-902
- DOI
  10.1111/j.1471-4159.2012.07748.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590265, KAKENHI-PROJECT-23370061, KAKENHI-PROJECT-23500437, KAKENHI-PROJECT-23659155, KAKENHI-PROJECT-23790353, KAKENHI-PUBLICLY-23112509, KAKENHI-PUBLICLY-24111508
[Journal Article] Dendritic cell-specific ablation of the protein tyrosine phosphatase shp1 promotes Th1 cell differentiation and induces autoimmunity.2012
- Author(s)
  Kaneko T., Saito Y., Kotani T., Okazawa H., Iwamura H., Sato-Hashimoto M., Kanazawa Y., Takahashi S., Hiromura K., Kusakari S.Kaneko Y., Murata Y., Ohnishi H., Nojima Y., Takagishi K., and Matozaki T.
- Journal Title
  
  J. Immunol
  
  Volume: 188 Issue: 11 Pages: 5397-5407
- DOI
  10.4049/jimmunol.1103210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590265, KAKENHI-PROJECT-23370061, KAKENHI-PROJECT-23500437, KAKENHI-PROJECT-23659155, KAKENHI-PROJECT-23700438, KAKENHI-PROJECT-23790353, KAKENHI-PROJECT-24590380, KAKENHI-PUBLICLY-23112509, KAKENHI-PUBLICLY-24111508
[Journal Article] Src family kinases : modulators of neurotransmitter receptor function and behavior2011
- Author(s)
  Ohnishi H., Murata Y., Okazawa H., Matozaki T.
- Journal Title
  
  Trends Neurosci.(Review)
  
  Volume: 34 Pages: 629-637
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590265
[Journal Article] Signal regulatory protein a regulates the homeostasis of T lymphocytes in the spleen2011
- Author(s)
  Sato-Hashimoto M., Murata Y., Matozaki T., et al
- Journal Title
  
  J.Immunol.
  
  Volume: 187 Pages: 291-297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590265
[Journal Article] Src family kinases: modulators of neurotransmitter receptor function and behavior.2011
- Author(s)
  Ohnishi H., Murata Y., Okazawa H., and Matozaki T.
- Journal Title
  
  Trends Neurosci
  
  Volume: 34 Issue: 12 Pages: 629-637
- DOI
  10.1016/j.tins.2011.09.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590265, KAKENHI-PROJECT-23370061, KAKENHI-PROJECT-23500437, KAKENHI-PROJECT-23659155
[Journal Article] Signal regulatory protein α regulates the homeostasis of T lymphocytes in the spleen.2011
- Author(s)
  Sato-Hashimoto M., Saito Y., Ohnishi H., Iwamura H., Kanazawa Y., Kusakari S., Kotani T., Mori M., Murata Y., Okazawa H., Ware CF., Olodenbrg PA., Nojima Y., and Matozaki T.
- Journal Title
  
  J. Immunol
  
  Volume: 187 Issue: 1 Pages: 291-297
- DOI
  10.4049/jimmunol.1100528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590265, KAKENHI-PROJECT-23370061, KAKENHI-PROJECT-23500437, KAKENHI-PROJECT-23659155, KAKENHI-PROJECT-23700438, KAKENHI-PROJECT-23790353
[Journal Article] Tyrosine phosphorylation of R3 subtype receptor-type protein tyrosine phosphatases and their complex formations with Grb2 or Fyn.2010
- Author(s)
  Murata, Y., Mori, M., Kotani, T., Supriatna, Y., Okazawa, H., Kusakari, S., Saito, Y., Ohnishi, H., Matozaki, T.
- Journal Title
  
  Genes Cells 15
  
  Pages: 513-524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] Tyrosine phosphorylation of R3 subtype receptor-type protein tyrosine phosphatases and their complex formations with Grb2 or Fyn.2010
- Author(s)
  Murata Y., Mori M., Kotani T., Supriatna Y., Okazawa H., Kusakari S., Saito Y., Ohnishi H., and Matozaki T
- Journal Title
  
  Genes Cells
  
  Volume: 15 Issue: 5 Pages: 513-524
- DOI
  10.1111/j.1365-2443.2010.01398.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590265
[Journal Article] Tyrosine phosphorylation of R3 subtype receptor-type protein tyrosine phosphatases and their complex formations with Grb2 or Fyn.2010
- Author(s)
  Murata, Y., et al.
- Journal Title
  
  Genes to Cells
  
  Volume: 15 Pages: 513-524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590265
[Journal Article] Promotion of cell spreading and migration by vascular endothelial-protein tyrosine phosphatase (VE-PTP) in cooperation with integrins.2010
- Author(s)
  Mori M., Murata Y., Kotani T., Kusakari S., Ohnishi H., Saito Y., Okazawa H., Ishizuka T., Mori M., and Matozaki T
- Journal Title
  
  J. Cell. Physiol.
  
  Volume: 224 Issue: 1 Pages: 195-204
- DOI
  10.1002/jcp.22122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590265
[Journal Article] Promotion of cell spreading and migration by vascular endothelial-protein tyrosine phosphatase (VE-PTP) in cooperation with integrins.2010
- Author(s)
  Mori, M., Murata, Y., Kotani, T., Kusakari, S., Ohnishi, H., Saito, Y., Okazawa, H., Ishizuka, T., Mori, M., Matozaki, T.
- Journal Title
  
  J. Cell. Physiol. 224
  
  Pages: 195-204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] localization, and biological function of the R3 subtype of receptor-type protein tyrosine phosphatases in mammals.2010
- Author(s)
  Matozaki T., Murata Y., Mori M., Kotani T., Okazawa H., and Ohnishi H. Expression
- Journal Title
  
  Cell. Signal
  
  Volume: 22 Issue: 12 Pages: 1811-1817
- DOI
  10.1016/j.cellsig.2010.07.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590265
[Journal Article] Protein tyrosine phosphatase SHP-2: A proto-oncogene product that promotes Ras activation.2009
- Author(s)
  Matozaki, T., Murata, Y., Saito, Y., Okazawa, H., Ohnishi, H.
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 1786-1793
- NAID
  10027195202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] Functions and molecular mechanisms of the CD47-SIRPα signalling pathway2009
- Author(s)
  Matozaki T., Murata Y., Okazawa H., and Ohnishi H
- Journal Title
  
  Trends Cell Biol. 19巻
  
  Pages: 72-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790205
[Journal Article] SAP-1 is a microvillus-specific protein tyrosine phosphatase that modulates intestinal tumorigenesis2009
- Author(s)
  Sadakata H., Okzawa H., Sato T., Supriatna Y., Ohnishi H., Kusakari S., Murata Y., Nishiyama U. Minegishi, T., Harada A., and Matozaki T
- Journal Title
  
  Genes Cells 14巻
  
  Pages: 295-308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790205
[Journal Article] SAP-1 is a microvillus-specific protein tyrosine phosphatase that modulates intestinal tumorigenesis.2009
- Author(s)
  Sadakata, H., Okazawa, H., Sato, T., Supriatna, Y., Ohnishi, H., Kusakari, S., Murata, Y., Ito, T., Nishiyama, U., Minegishi, T., Harada, A., Matozaki, T.
- Journal Title
  
  Genes Cells 14
  
  Pages: 295-308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] Functions and molecular mechanisms of the CD47-SIRPα signalling pathway.2009
- Author(s)
  Matozaki, T., Murata, Y., Okazawa, H., Ohnishi, H.
- Journal Title
  
  Trends Cell Biol. 19
  
  Pages: 72-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] Trans-endocytosis of CD47 and SHPS-1 and its role in regulation of the CD47-SHPS-1 system.2008
- Author(s)
  Kusakari, S., Ohnishi, H., Jin, F. -J., Kaneko, Y., Murata, T., Murata, Y., Okazawa, H., Matozaki, T.
- Journal Title
  
  J. Cell Sci. 121
  
  Pages: 1213-1223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] Essential Roles of SHPS-1 in induction of contact hypersensitivity of skin2008
- Author(s)
  Motegi S., Okazawa H., Murata Y., Knazawa Y., Saito Y., Kobayashi H., Ohnishi H., Oldenborg PA., Ishikawa O., and Matozaki T
- Journal Title
  
  Immunol. Lett. 121巻
  
  Pages: 52-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790205
[Journal Article] Negative regulation by SHPS-1 of Toll-like receptor-dependent proinflammatory cytokine production in macrophages.2008
- Author(s)
  Miyake A., Murata Y., Okzawa H., Ikeda H., Niwayama Y., Ohnishi H., Hirata Y., and Matozaki T
- Journal Title
  
  Genes Cells 13巻
  
  Pages: 209-219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790205
[Journal Article] Expression of SHPS-1 in pancreatic ・ cells and its role in promotion of insulin secretion and protection against diabetes.2008
- Author(s)
  Kobayashi M., Ohnishi H., Okazawa H., Murata Y., Hayashi Y., Kitamura T., and Matozaki T
- Journal Title
  
  Endocrinology 149巻
  
  Pages: 5662-5669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790205
[Journal Article] Resistance to collagen-induced arthritis in SHPS-1 mutant mice2008
- Author(s)
  Okuzawa C., Kaneko Y., Murata Y., Miyake A., Saito Y., Okajo J., Tomizawa T., Kaneko Y., Okazawa H., Ohnishi H., Matozaki T., and Nojima Y
- Journal Title
  
  Biochem. Biophys. Res. Commun. 371巻
  
  Pages: 561-566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790205
[Journal Article] Negative regulation by SHPS-1 of Toll-like receptor-dependent proinflammatory cytokine production in macrophages.2008
- Author(s)
  Miyake, A., Murata, Y., Okazawa, H., Ikeda, H., Niwayama, Y., Ohnishi, H., Hirata, Y., Matozaki, T.
- Journal Title
  
  Genes Cells 3
  
  Pages: 209-219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] Trans-endocytosis of CD47 and SHPS-1 and its role in regulation of the CD47-SHPS-1 system2008
- Author(s)
  Kusakari S., Ohnishi H., Jin F.J., Kaneko Y., Murata T., Murata, Y., Okazawa H., and Matozaki T
- Journal Title
  
  J. Cell Sci. 121巻
  
  Pages: 1213-1223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790205
[Journal Article] Essential roles of SHPS-1 in induction of contact hypersensitivity of skin.2008
- Author(s)
  Motegi, S., Okazawa, H., Murata, Y., Kanazawa, Y., Saito, Y., Kobayashi, H., Ohnishi, H., Oldenborg, P. -A., Ishikawa, O., Matozaki, T.
- Journal Title
  
  Immunol. Lett. 121
  
  Pages: 52-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] Regulation by SHPS-1 of α-GalCer-induced antimetastatic activity2007
- Author(s)
  Okajo J., Kaneko Y., Murata Y., Tomizawa T., Okuzawa C., Saito Y., Kaneko Y., Ishikawa-Sekigami T., Okazawa H., Ohnishi H., Matozaki T., and Nojima H
- Journal Title
  
  J. Immunol 178巻
  
  Pages: 6164-6172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790205
[Journal Article] Regulation by Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 of α-galactosylceramide-induced antimetastatic activity and Th1 and Th2 responses of NKT cells.2007
- Author(s)
  Okajo, J., Kaneko, Y., Murata, Y., Tomizawa, T., Okuzawa, C., Saito, Y., Kaneko, Y., Ishikawa-Sekigami, T., Okazawa, H., Ohnishi, H., Matozaki, T. Nojima, Y.
- Journal Title
  
  J. Immunol. 178
  
  Pages: 6164-6172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] Resistance to experimental autoimmune encephalomyelitis and impaired T cell priming by dendritic cells in SHPS-1 mutant mice.2007
- Author(s)
  Tomizawa, T., Kaneko, Y., Kaneko, Y., Saito, Y., Ohnishi, H., Okajo, J., Okuzawa, C., Ishikawa-Sekigami, T., Murata, Y., Okazawa, H., Okamoto, K., Nojima, Y. Matozaki, T.
- Journal Title
  
  J. Immunol. 179
  
  Pages: 869-877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] Resistance to experimental autoimmune encephalomyelitis and impaired T cell priming by dendritic cells in SHPS-1 mutant mice2007
- Author(s)
  Tomizawa T., Kaneko Y., Kaneko Y., Saito Y., Ohnishi H., Okajo J., Okuzawa C., Ishikawa-Sekigami T., Murata, Y., Okazawa H., Okamoto K., Nojima H., and Matozaki T
- Journal Title
  
  J. Immunol. 179巻
  
  Pages: 869-877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790205
[Journal Article] CD47 regulation of epithelial cell spreading and migration, and its signal transduction.2006
- Author(s)
  Shinohara, M., Ohyama, N., Murata, Y., Okazawa, H., Ohnishi, H., Ishikawa, O., Matozaki, T.
- Journal Title
  
  Cancer Sci. 97
  
  Pages: 889-895
- NAID
  10018767488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] CD47 promotes neuronal development through Src-and FRG/Vav2-mediated activation of Rac and Cdc42.2006
- Author(s)
  Murata, T., et al.
- Journal Title
  
  J.Neurosci. 26巻・48号
  
  Pages: 12397-12407
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] Mutational analysis of the mechanism of negative regulation by SHPS-1 of phagocytosis in macrophages.2006
- Author(s)
  Ikeda, H., Okazawa, H., Ohnishi, H., Murata, Y., Oldenborg, P. -A. Matozaki, T.
- Journal Title
  
  J. Immunol. 177
  
  Pages: 3123-3132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Journal Article] CD47 Promotes Neuronal Development through Src- and FRG/Vav2-Mediated Activation of Rac and Cdc42.2006
- Author(s)
  Murata, T., et al.
- Journal Title
  
  The Journal of Neuroscience 26巻・48号
  
  Pages: 12397-12407
- Data Source
  KAKENHI-PROJECT-18890040
[Journal Article] Tyrosine phosphorylation of R3 subtype receptor-type protein tyrosine phosphatases and their complex formations with Grb2 or Fyn
- Author(s)
  Murata, Y., 他
- Journal Title
  
  Genes Cells (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014010
[Patent] 抗腫瘍剤2016
- Inventor(s)
  的崎　尚、村田陽二
- Industrial Property Rights Holder
  的崎　尚、村田陽二
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-133638
- Filing Date
  2016-07-05
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] SIRPα, a potential therapeutic target for the head and neck cancer2024
- Author(s)
  Takashi Ueda, Yoji Murata, Daisuke Tanaka, Oduori S. Okechi, Saki Matsumoto, Yasuyuki Saito, Takenori Kotani, Ken-Ichi Nibu, Takashi Matozaki
- Organizer
  第11回日本プロテインホスファターゼ研究会学術集会/The 5th Japan-Taiwan Bilateral Conference on Protein Phosphatase
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06926
[Presentation] CD47 promotes peripheral T cell survival by preventing dendritic cell-mediated T cell necroptosis2024
- Author(s)
  Satomi Komori, Yasuyuki Saito, Tania Afrof, Tomoko Takai, Okechi S. Oduori, Takenori, Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K06926
[Presentation] 樹状細胞は膜分子CD47を介して抹消組織T細胞の生存を制御する2023
- Author(s)
  小森里美、Tania Afroj、高井智子、Oduori S. Okechi、小谷武徳、村田陽二、的崎尚、齊藤泰之
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06926
[Presentation] 膜蛋白質SIRPβ1の機能制御による抗腫瘍免疫作用2023
- Author(s)
  村田陽二、Oduori S. Okechi、上田隆、坂本茉莉子、田中大介、小谷武徳、齊藤泰之、的崎尚
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K06926
[Presentation] CD47欠損細胞の生体からの排除におけるCD11c/SIRPα陽性樹状細胞の重要性2023
- Author(s)
  高井智子、小谷武徳、小森里美、齊藤泰之、村田陽二、的崎尚
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06926
[Presentation] Therapeutic potential of anti-SIRPβ1 antibodies and its mechanism of action in cancers2023
- Author(s)
  Okechi S.Oduori, Daisuke Tanaka, Tomoko Takasi, Takashi Ueda, Mariko Sakamoto, Takenori Kotani, Yasuyuki Saito, Takashi Matozaki, Yoji Murata
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06926
[Presentation] Preclinical evaluation of macrophage-targeted immunotherapy in vivo using a humanized mouse model2023
- Author(s)
  Yasuyuki Saito, Tania Afroj, Rie Iida-Norita, Satomi Komori, Tomoko Takasi, Oduori S. Okechi, Takenori Kotani, Yu-ichiro Koma, Yoji Murata, Hiroshi Yokozaki, Takashi Matozaki
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06926
[Presentation] 新規ヒト化マウスを用いたマクロファージを介した抗腫瘍効果の前臨床評価モデル2022
- Author(s)
  齊藤泰之、飯田理恵、小森里美、小谷武徳、村田陽二、横崎宏、的崎尚
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06926
[Presentation] マクロファージ SIRPβ1を標的とした新たながん免疫療法2022
- Author(s)
  村田陽二、坂本茉莉子、高井智子、齊藤泰之、小谷武徳、的崎尚
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06926
[Presentation] 自然免疫系細胞の制御によるSIRPファミリー分子を標的とする新規がん治療法の開発2022
- Author(s)
  的崎尚、村田陽二、齊藤泰之、小谷武徳
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06926
[Presentation] マクロファージによるがん細胞貪食を制御する分子基盤の解明2022
- Author(s)
  小谷武徳、高井智子、齊藤泰之、村田陽二、的崎尚
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06926
[Presentation] 細胞間シグナルCD47-SIRPα系を標的とする環状ペプチドの開発と抗がん剤としての応用2022
- Author(s)
  村田陽二
- Organizer
  日本がん分子標的治療学会　第17回TRワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-19K07385
[Presentation] マクロファージよる生細胞貪食を制御する分子基盤の解明2022
- Author(s)
  小谷武徳, 高井智子, 齊藤泰之, 村田陽二, 的崎　尚
- Organizer
  第10回日本プロテインホスファターゼ研究会学術集
- Data Source
  KAKENHI-PROJECT-19K07385
[Presentation] 細胞間シグナルCD47-SIRPα系による細胞貪食制御機序とその新規がん治療法への応用2022
- Author(s)
  小谷　武徳、高井智子、小森里美、齊藤　泰之、村田　陽二、的崎　尚
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K06926
[Presentation] A novel humanized mouse model in vivo evaluation of cancer immunotherapy targeting human macrophages2021
- Author(s)
  Saito Y, Iida R, Hazama D, Kotani T, Murata Y, Yokozaki H, Matozaki T
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07385
[Presentation] Preclinical Evaluation of the efficacy of anti-human SIRPα antibody for cancer immunotherapy by the use of humanized mice2021
- Author(s)
  Saito Y, Iida-Norita R, Hazama D, Alaa R, Komori S, Kotani T, Murata Y, Matozaki T
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07385
[Presentation] ランゲルハンス組織球症に対する抗SIRPα抗体の効果2021
- Author(s)
  岡本武士, 村田陽二、羽間大祐, 坂本茉莉子, 角地宥香, 田中大介, 増田重人, 齊藤泰之, 小谷武徳, 眞庭謙昌, 的崎　尚
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07385
[Presentation] SIRPα supports the survival of dendritic cells by regulating the NF-kB activation, Komori S2021
- Author(s)
  Komori S, Saito Y, Datu R, Kotani T, Murata Y, Matozaki T
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07385
[Presentation] 新規がん免疫療法ターゲット分子としての膜型分子SIRPβ1/SIRPβ12021
- Author(s)
  坂本茉莉子, 村田陽二, 角地宥香, 岡本武士, 田中大介, 羽間大祐, 増田重人, 齊藤泰之, 小谷武徳, 藤澤正人, 的崎　尚
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07385
[Presentation] 抗SIRPα/β1抗体によるマクロファージを介したがん免疫療法の基礎的研究2021
- Author(s)
  村田陽二, 坂本茉莉子, 岡本武士, 齊藤泰之, 小谷武徳, 藤澤正人, 的崎　尚
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07385
[Presentation] Antitumor effects of agents targeting SIRPα an immune checkpoint, and their combination with other agents2021
- Author(s)
  Murata Y, Saito Y, Kotani T, Matozaki T
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07385
[Presentation] The antitumor effect of monotherapy with an anti-SIRPα antibody against bladder cancer cells2021
- Author(s)
  Murata Y, Sakamoto M, Okamoto T, Saito Y, Kotani T, Matozaki T
- Organizer
  2021 JCA-AACR JCA-AACR Precision Cancer Medicine International Conference
- Data Source
  KAKENHI-PROJECT-19K07385
[Presentation] Antibodies to SIRPα/SIRPβ as a potential tool for immunotherapy of bladder cancer2020
- Author(s)
  Mariko Sakamoto, Yoji Murata, Yuka Kakuchi, Daisuke Takana, Takeshi Okamoto, Yasuyuki Saito, Takenori Kotani, Masato Fujisawa, Takashi Matozaki
- Organizer
  14th International Conference on Protein Phosphatase
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07385
[Presentation] 細胞間シグナルCD47-SIRPα系を制御する大環状ペプチドの創出と抗腫瘍剤としての応用2020
- Author(s)
  村田　陽二、羽間　大祐、Yin Yizhen、松田　真、岡本　武士、田中　大介、坂本　茉莉子、角地　宥香、寺坂　尚紘、 Zhao Jinxuan、齊藤　泰之、小谷　武徳、中川　敦史、菅　裕明、的崎　尚
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07385
[Presentation] 膜型分子SIRPα/SIRPβ特異抗体を用いた膀胱がんに対する新規抗体療法2020
- Author(s)
  坂本　茉莉子、村田　陽二、羽間　大祐、岡本　武士、角地　宥香、齊藤　泰之、小谷　武徳、藤沢　正人、的崎　尚
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07385
[Presentation] ランゲルハンス細胞組織球症に対する新規治療標的分子SIRPα2020
- Author(s)
  岡本　武士、村田　陽二、羽間　大祐、坂本　茉莉子、角地　宥香、齊藤　泰之、小谷　武徳、眞庭　謙昌、的崎　尚
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07385
[Presentation] 抗SIRPα抗体を用いた膀胱がんに対する新規がん免疫療法開発2020
- Author(s)
  坂本　茉莉子、村田　陽二、田中　大介、岡本　武士、羽間　大祐、角地　宥加、齊藤　泰之、小谷　武徳、的崎　尚
- Organizer
  第19回生体機能研究会
- Data Source
  KAKENHI-PROJECT-19K07385
[Presentation] Blockade of the CD47-SIRPα interaction by SIRPα-binding macrocyclic peptides as a potential cancer immunotherapy2020
- Author(s)
  Yoji Murata, Daisuke Hazama, Yizhen Yin, Mariko Sakamoto, Yasuyuki Saito, Takenori Kotani, Hiroaki Suga, Takashi Matozaki
- Organizer
  14th International Conference on Protein Phosphatase
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07385
[Presentation] チロシンホスファターゼ SHP-1/2 結合タンパク質 SIRPαによる自然免疫細胞の機能制御2019
- Author(s)
  村田陽二, 齊藤泰之 ,小谷武徳, 的崎尚
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07385
[Presentation] 膜型分子SIRPαを標的とする新たな免疫チェックポイント阻害剤の開発2019
- Author(s)
  羽間大祐, 村田陽二, 田中大介, 岡本武士, 齊藤泰之, 小谷武徳, 西村善博, 的崎尚
- Organizer
  第9回日本ホスファターゼ研究会学術集会
- Data Source
  KAKENHI-PROJECT-19K07385
[Presentation] A nobel macrocycle peptide targets CD47-SIRPalpha axis and enhances the macrophage-mediated tumor killing2019
- Author(s)
  羽間大祐, 村田陽二, 田中大介, 岡本武士, 齊藤泰之, 小谷武徳, 西村善博, 的崎尚
- Organizer
  第78回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-19K07385
[Presentation] 新規SIRPα阻害剤の開発とその抗腫瘍効果2019
- Author(s)
  村田陽二, 羽間大祐, 田中大介, 岡本武士, 齊藤泰之, 小谷武徳, 的崎尚,
- Organizer
  第18回生体機能研究会
- Data Source
  KAKENHI-PROJECT-19K07385
[Presentation] 腸炎症制御における腸上皮Srcファミリーキナーゼの役割2018
- Author(s)
  孫春暁、村田陽二、今田慎也、小谷武徳、齊藤泰之、山田秀人、的崎　尚
- Organizer
  第77回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-16K08624
[Presentation] Srcファミリーキナーゼの炎症性腸疾患における重要性2018
- Author(s)
  孫春暁、村田陽二、今田慎也、小谷武徳、齊藤泰之、山田秀人、的崎　尚
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K08624
[Presentation] 腸上皮細胞の恒常生維持に関わるチロシンリン酸化シグナルの意義2018
- Author(s)
  的崎　尚、村田陽二、小谷武徳、齊藤泰之
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K08624
[Presentation] Role of Csk in the regulation of intestinal homeostasis and the development of inflammation in the colon2018
- Author(s)
  孫春暁、村田陽二、今田慎也、小谷武徳、齊藤泰之、山田秀人、的崎　尚
- Organizer
  第65回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-16K08624
[Presentation] Regulation of intestinal immunity by the microvillus-specific protein tyrosine phosphatase SAP-1 and its substrate CEACAM20.2017
- Author(s)
  Kotani T, Murata Y, Supriatna Y, Kitamura Y, Imada S, Saito Y, Okazawa H, Ohnishi H, and Matozaki T.
- Organizer
  Europhosphatase 2018: Phosphatases in cell fates and decisions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08624
[Presentation] Role of Src family kinases in regulation of intestinal epithelial homeostasis.2017
- Author(s)
  Murata Y, Imada S, Kotani T, Sun C, Saito Y, and Matozaki T.
- Organizer
  Europhosphatase 2018: Phosphatases in cell fates and decisions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08624
[Presentation] Regulation of interestinal epithelial homeostasis by Src family kinases through Rac and YAP.2017
- Author(s)
  Murata Y, Imada S, Kotani T, Sun C, Saito Y, and Matozaki T.
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K08624
[Presentation] Role of SIRPαin the homeostasis of fibroblastic reticular cells by dendritic cells in the spleen2016
- Author(s)
  Datu Respatika, Yasuyuki Saito, Ken Washio, Satomi Komori, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  第12回プロテインホスファターゼ国際カンファレンス＆革新がんゲノム国際シンポジウム
- Place of Presentation
  近畿大学東大阪キャンパス
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] The anti-SIRPα antibody prevents tumor formation: a novel strategy for cancer therapy /抗SIRPα抗体を用いた新たながん治療法2016
- Author(s)
  栁田　匡彦、村田　陽二、田中　大介、齊藤　泰之、小谷　武徳、古森　孝英、的崎　尚
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] 受容体型チロシンホスファターゼSAP-1による腸管免疫制御2016
- Author(s)
  村田　陽二、小谷　武徳、齊藤　泰之、的崎　尚
- Organizer
  第15回生体機能研究会
- Place of Presentation
  淡路夢舞台国際会議場
- Year and Date
  2016-07-01
- Data Source
  KAKENHI-PROJECT-16K08624
[Presentation] Role of Src family kinases in regulatin of intestinal epithelial homeostasis2016
- Author(s)
  Shinya Imada, Yoji Murata, Takenori Kotani, Masaki Hatano, Chunxiao Sun, Tasuku Konno, Yasuyuki Saito, Hideki Ohdan, Takahi Matozaki
- Organizer
  第12回プロテインホスファターゼ国際カンファレンス＆革新がんゲノム国際シンポジウム
- Place of Presentation
  近畿大学東大阪キャンパス
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08624
[Presentation] 白質におけるミクログリア恒常性制御2016
- Author(s)
  野津　智美、橋本　美穂、Ruwaida Elhanbaly、石川　達也、齊藤　泰之、小谷　武徳、村田　陽二、深澤　有吾、的崎　尚、大西　浩史
- Organizer
  第38回日本生物学的精神医学会、第59回日本神経化学会大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Role of SIRPα on dendritic cells in homeostatic regulation of fibroblastic reticular cells in the spleen2016
- Author(s)
  Datu Respatika, Yasuyuki Saito, Ken Washio, Satomi Komori, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] SIRPα欠損マウスはLPS投与によって誘導される低体温症が重症化する2016
- Author(s)
  橋本　美穂、野津　智美、浦野　江里子、齊藤　泰之、小谷　武徳、村田　陽二、的崎　尚、大西　浩史
- Organizer
  第38回日本生物学的精神医学会、第59回日本神経化学会大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Role of SIRPαon dendritic cells in homeostatic regulation of fibroblastic reticular cells in the spleen2016
- Author(s)
  Datu Respatika, Yasuyuki Saito, Ken Washio, Satomi Komori, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  第15回生体機能研究会
- Place of Presentation
  淡路夢舞台国際会議場
- Year and Date
  2016-07-01
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Therapeutic application of anti-SIRPαantibody in cancer treatment2016
- Author(s)
  Tadahiko Yanagita, Yoji Murata, Daisuke Tanaka, Yasuyuki Saito, Takenori Kotani, Takahide Komori, Takashi Matozaki
- Organizer
  第12回プロテインホスファターゼ国際カンファレンス＆革新がんゲノム国際シンポジウム
- Place of Presentation
  近畿大学東大阪キャンパス
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] 細胞間シグナルCD47-SIRPα系の生理機能とその臨床応用/Role of the CD47-SIRPalpha system and its therapeutic application2016
- Author(s)
  的崎　尚、村田　陽二、齊藤　泰之、小谷　武徳、栁田　匡彦、田中　大介、大西　浩史
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-09-26
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Essential Role of SIRPα on Dendritic Cells in Homeostatic Regulation of Spleen Stromal Cells2016
- Author(s)
  Datu Respatika, Yasuyuki Saito, Ken Washio, Satomi Komori, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  第7回日本プロテインホスファターゼ研究会学術集会
- Place of Presentation
  基礎生物学研究所（愛知県・岡崎市）
- Year and Date
  2016-01-29
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] SAP-1 and CEACAM20 protect against colitis in the intestinal epithelium2015
- Author(s)
  Yoji Murata, Takenori Kotani, Yana Supriatna, Yasuaki Kitamura, Shinya Imada, Yasuyuki Saito, Hideki Okazawa, Hiroshi Ohnishi, Takashi Matozaki
- Organizer
  FASEB
- Place of Presentation
  The Steamboat Grand, SteamboatSprings （USA）
- Year and Date
  2015-08-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] SAP-1 and CEACAM20 protect against colitis in the intestinal epithelium2015
- Author(s)
  Yoji Murata, Takenori Kotani, Yana Supriatna, Yasuaki Kitamura, Shinya Imada, Yasuyuki Saito, Hideki Okazawa, Hiroshi Ohnishi, Takashi Matozaki
- Organizer
  FASEB
- Place of Presentation
  The Steamboat Grand, SteamboatSprings(USA)
- Year and Date
  2015-08-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] 腸上皮組織の恒常性制御におけるCskとSrcファミリーキナーゼの役割/Role of C-terminal Src kinase(Csk) and Src family kinases in homeostasis of the intestinal epithelium2015
- Author(s)
  今田　慎也、村田　陽二、北村　泰明、朴　貞河、畑野　正樹、金野　祐、小谷　武徳、齊藤　泰之、大段　秀樹、的崎　尚
- Organizer
  BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会合同大会）
- Place of Presentation
  兵庫県神戸市(神戸ポートピアホテル)
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] 細胞間シグナル伝達システムCD47-SIRPα系のがん治療への応用2015
- Author(s)
  栁田　匡彦、村田　陽二、田中　大介、小谷　武徳、齊藤　泰之、古森　孝英、的崎　尚
- Organizer
  第14回生体機能研究会
- Place of Presentation
  ザ・プリンス箱根（神奈川県・箱根町）
- Year and Date
  2015-07-25
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Analysis of cell-cell interaction signal that regulates microglial homeostasis/ミクログリア恒常性を制御する細胞間相互作用シグナルの解析2015
- Author(s)
  Miho Sato-Hashimoto, Tomomi Nozu, Eriko Urano, Takenori Kotani, Yoji Murata, Takashi Matozaki, Hiroshi Ohnishi
- Organizer
  Neuroscience 2015　第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場/神戸国際展示場（兵庫県・神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] 腸粘膜上皮細胞の微絨毛に局在する受容体型チロシンホスファターゼSAP-1とCEACAM20による腸管免疫制御/Regulation of intestinal immunity by the microvillus-specific protein tyrosine phosphatase SAP-1 and CEACAM202015
- Author(s)
  村田　陽二、小谷　武徳、Yana Supriatna、北村　泰明、今田　慎也、齊藤　泰之、大西　浩史、的崎　尚
- Organizer
  第67回日本細胞生物学会大会
- Place of Presentation
  東京都江戸川区(タワーホール船堀)
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] Role of C-terminal Src kinase(Csk) and Src family kinases in homeostasis of the intestinal epithelium2015
- Author(s)
  Shinya Imada, Yoji Murata, Yasuaki Kitamura, Jung-ha Park, Masaki Hatano, Takenori Kotani, Yasuyuki Saito, Hideki Ohdan, Takashi Matozaki
- Organizer
  FASEB
- Place of Presentation
  The Steamboat Grand, SteamboatSprings （USA）
- Year and Date
  2015-08-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] クラス3受容体型チロシンホスファターゼSAP-1による腸管免疫制御 /　Regulation of intestinal immunity by R3-subtype receptor-type protein tyrosine phosphatase SAP-12015
- Author(s)
  村田　陽二、小谷　武徳、齋藤　泰之、岡澤　秀樹、大西　浩史、的崎　尚
- Organizer
  BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会合同大会）
- Place of Presentation
  兵庫県神戸市(神戸ポートピアホテル)
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] Essential role of SIRPα on dendritic cells in Homeostatic regulation of the secondary lymphoid organ2015
- Author(s)
  Datu Respatika, Yasuyuki Saito, Ken Washio, Satomi Komori, Takenori Kotani, Yoji Murata, Yoriaki Kaneko, Hideki Okazawa, Hiroshi Ohnishi, Atsushi Fukunaga, Chikako Nishigori, and Takashi Matozaki
- Organizer
  2015University of Washington and Kobe University joint symposium 2015神戸大学・ワシントン大学国際合同シンポジウム
- Place of Presentation
  University of Washington, Seattle （USA）
- Year and Date
  2015-09-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] 腸上皮組織の恒常性制御におけるCskとSrcファミリーキナーゼの役割/Role of C-terminal Src kinase(Csk) and Src family kinases in homeostasis of the intestinal epithelium2015
- Author(s)
  今田　慎也、村田　陽二、北村　泰明、朴　貞河、小谷　武徳、齊藤　泰之、大段　秀樹、的崎　尚
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  愛知県名古屋市(名古屋国際会議場)
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] Behavioral analysis of forebrain neuron-specific Shp2 conditional knockout mice/前脳神経細胞特異的Shp2コンディショナルKOﾏｳｽの行動解析2015
- Author(s)
  Hiroshi Ohnishi, Shinya Kusakari, Miho Sato-Hashimoto, Shuya Ishikawa, Eriko Urano, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  Neuroscience 2015　第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場/神戸国際展示場（兵庫県・神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Regulation by microbiota of intestinal epithelium turnover2014
- Author(s)
  Jung-ha Park, Takenori Kotani, Yasuaki Kitamura, Yoji Murata, Takashi Matozaki
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市（パシフィコ横浜）
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] 腸管におけるCEACAM20の発現と腸内細菌叢を介した発現制御2014
- Author(s)
  北村泰明、村田陽二、朴貞河、小谷武徳、岡澤秀樹、東健、的崎尚
- Organizer
  第13回生体機能研究会
- Place of Presentation
  岐阜県岐阜市（ホテルパーク）
- Year and Date
  2014-07-19
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] Regulation by the intestinal microflora of Carcinoembryonic antigen-related cell adhesion molecule (CEACAM) 20 expression in intestinal epithelial cells2014
- Author(s)
  Yasuaki Kitamura, Yoji Murata, Jung-ha Park, Takenori Kotani, Takeshi Azuma, Takashi Matozaki
- Organizer
  第11回プロテインホスファターゼ国際カンファレンス
- Place of Presentation
  宮城県仙台市（東北大学医学部艮陵会館）
- Year and Date
  2014-11-12
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] 腸上皮の恒常性維持におけるチロシンホスファターゼShp2の役割/Roles of the protein tyrosine phosphatase Shp2 in maintaining homeostasis of the intestinal epithelium2014
- Author(s)
  小谷武徳、山下博成、村田陽二、岡澤秀樹、大西浩史、具英成、的崎尚
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都府京都市（国立京都国際会館・グランドプリンスホテル京都）
- Year and Date
  2014-10-17
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] 腸上皮の恒常性維持におけるチロシンホスファターゼShp2の役割2014
- Author(s)
  小谷武徳、山下博成、朴貞河、村田陽二、岡澤秀樹、大西浩史、具英成、的崎尚
- Organizer
  第6回日本プロテインホスファターゼ研究会学術集会
- Place of Presentation
  三重大学
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] Roles of protein tyrosine phosphatases in homeostasis of intestinal epithelium2014
- Author(s)
  Takashi Matozaki, Yoji Murata, Takenori Kotani, Yasuyuki Saito
- Organizer
  第11回プロテインホスファターゼ国際カンファレンス
- Place of Presentation
  宮城県仙台市（東北大学医学部艮陵会館）
- Year and Date
  2014-11-13
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] Regulation of intestinal immunity by the protein tyrosine phosphatase SAP-12014
- Author(s)
  Yoji Murata
- Organizer
  University of Washington and Kobe University International Joint Symposium
- Place of Presentation
  兵庫県神戸市（神戸ポートピアホテル）
- Year and Date
  2014-12-16
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] 樹状細胞及び二次リンパ組織の恒常性維持におけるSIRPαの役割2014
- Author(s)
  鷲尾健, 小谷武徳, レスパティカダトゥ, 村田陽二, 岡澤秀樹, 大西浩史, 福永淳, 錦織千佳子, 的崎尚
- Organizer
  第6回日本プロテインホスファターゼ研究会学術集会
- Place of Presentation
  三重大学(三重)
- Year and Date
  2014-02-21
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] Role of VE-PTP in shear stress responses of endothelial cells2014
- Author(s)
  Isnainiasih Mantilidewi Kemala, Yoji Murata, Munemasa Mori, Takenori Kotani, Shinya Kusakari, Hideki Okazawa, Hiroshi Ohnishi, and Takashi Matozaki
- Organizer
  ワシントン大学・神戸大学国際合同シンポジウム
- Place of Presentation
  ワシントン大学(Seattle, USA)
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] Shp2ホスファターゼはRas活性化を介して腸上皮の恒常性と腸炎発症を制御する/Shp2 phosphatase regulates homeostasis of intestinal epithelium and development of colitis through Ras activation2014
- Author(s)
  Takashi Matozaki, Hironori Yamashita, Takenori Kotani, Jung-ha Park, Yoji Murata, Hideki Okazawa, Hiroshi Ohnishi, Yonson Ku
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  神奈川県横浜市（パシフィコ横浜）
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] 腸上皮の恒常性維持におけるチロシンホスファターゼShp2の役割/Roles of the protein tyrosine phosphatase Shp2 in maintaining homeostasis of the intestinal epithelium2014
- Author(s)
  小谷武徳、山下博成、村田陽二、岡澤秀樹、大西浩史、具英成、的崎尚
- Organizer
  第66回日本細胞生物学会大会
- Place of Presentation
  奈良県奈良市（奈良県新公会堂・東大寺総合文化文化センター・奈良国立博物館）
- Year and Date
  2014-06-12
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] 腸管におけるCEACAM20の発現と腸内細菌叢を介した発現制御/Expression of CEACAM20 in intestine epithelial cells and regulation of its expression by intestinal microflora2014
- Author(s)
  北村泰明、村田陽二、朴貞河、今田慎也、小谷武徳、岡澤秀樹、東健、的崎尚
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都府京都市（国立京都国際会館・グランドプリンスホテル京都）
- Year and Date
  2014-10-17
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] Regulation by the intestinal microflora of carcinoembryonic antigen-related cell adhesion molecule (CEACAM) 20 expression in intestinal epithelial cells2014
- Author(s)
  Yasuaki Kitamura, Yoji Murata, Jung-ha Park, Takenori Kotani, Takeshi Azuma, Takashi Matozaki
- Organizer
  University of Washington and Kobe University International Joint Symposium
- Place of Presentation
  兵庫県神戸市（神戸ポートピアホテル）
- Year and Date
  2014-12-15
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] Functional Analysis of A non-receptor type protein tyrosine phosphatase Shp2 in the adult brain Neuro20132013
- Author(s)
  Kusakari S, Saitow F, Sato-Hashimoto M, Shibasaki K, Ago Y, Matsuda T, Benjamin G. Neel, Kotani T, Murata Y, Matozaki T, Ohnishi H
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2013-06-20
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] 腸上皮の恒常性維持におけるチロシンホスファターゼShp2 の役割2013
- Author(s)
  山下博成、小谷武徳、村田陽二、岡澤秀樹、大西浩史、具英成、的崎尚
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  神奈川（パシフィコ横浜）
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] The protein tyrosine phosphatase SAP-1 protects against colitis through regulation of CEACAM in the intestinal epithelium FASEB2013
- Author(s)
  Matozaki T, Murata Y, Kotani T, Yana Supriatna, Okazawa H, Ohnishi H
- Place of Presentation
  The Steamboat Grand(SteamboatSprings/USA)
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] Role of VE-PTP in shear stress responses of endothelial cells2013
- Author(s)
  Mantilidewi KI, Murata Y, Mori M, Kotani T, Kusakari S, Okazawa H, Ohnishi H, Matozaki T
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2013-09-11
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] R3受容体型チロシンホスファターゼの発現, 局在と生理機能2013
- Author(s)
  的崎尚, 村田陽二, 小谷武徳, Yana Supriatna, 森宗昌, 岡澤秀樹, 大西浩史
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場ほか(兵庫)
- Year and Date
  2013-12-05
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] The protein tyrosine phosphatase SAP-1 protects against colitis through regulation of CEACAM in the intestinal epithelium2013
- Author(s)
  Takashi Matozaki, Yoji Murata, Takenori Kotani, Yana Supriatna, Hideki Okazawa, Hiroshi Ohnishi
- Organizer
  FASEB
- Place of Presentation
  USA・The Steamboat Grand （SteamboatSprings）
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] Regulation of intestinal immunity by the protein tyrosine phosphatase SAP-12013
- Author(s)
  Murata Y, Kotani T, Yana Supriatna, Daniwijaya EW, Ohnishi H, Matozaki T
- Organizer
  第10回プロテインホスファターゼ国際カンファレンス
- Place of Presentation
  国立がん研究センター(東京)
- Year and Date
  2013-02-08
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] R3 受容体型チロシンホスファターゼの発現、局在と生理機能2013
- Author(s)
  的崎尚、村田陽二、小谷武徳、Yana Supriatna、森宗昌、岡澤秀樹、大西浩史
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  兵庫（神戸国際会議場、ポートピアホテル）
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] 腸上皮の恒常性維持におけるチロシンホスファターゼShp2の役割2013
- Author(s)
  小谷武徳、山下博成、村田陽二、岡澤秀樹、大西浩史、具英成、的崎尚
- Organizer
  第12回生体機能研究会
- Place of Presentation
  群馬県渋川市（ホテル木暮）
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] 受容体型チロシンホスファターゼSAP-1 による腸管免疫制御2013
- Author(s)
  村田陽二、小谷武徳、Supriatna Yana 、森宗昌、草苅伸也、岡澤秀樹、大西浩史、的崎尚
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  神奈川（パシフィコ横浜）
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] Roles of the protein tyrosine phosphatase Shp2 in maintaining homeostasis of the intestinal epithelium2013
- Author(s)
  小谷武徳、山下博成、村田陽二、岡澤秀樹、大西浩史、具英成、的崎尚
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  神奈川（パシフィコ横浜）
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] Roles of the protein tyrosine phosphatase Shp2 in homeostasis of the intestinal epithelium2013
- Author(s)
  Takenori Kotani, Hironori Yamashita, Yoji Murata, Hideki Okazawa, Hiroshi Ohnishi, Takashi Matozak
- Organizer
  FASEB
- Place of Presentation
  USA・The Steamboat Grand （SteamboatSprings）
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] SIRPα -CD47 system regulates the homeostasis of dendritic cells in lymphoid tissues2013
- Author(s)
  Washio K, Kotani T, Datu Respatika, Murata Y, Okazawa H, Ohnishi H, Fukunaga A, Nishigori C, Matozaki T
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ(千葉)
- Year and Date
  2013-12-12
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] Microbiota modulates the turnover of intestinal epithelial cells2013
- Author(s)
  Jung-ha Park, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  FASEB
- Place of Presentation
  USA・The Steamboat Grand （SteamboatSprings）
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] Role of VE-PTP in shear stress responses of endothelial cells2013
- Author(s)
  Isnainiasih Mantilidewi Kemala, Yoji Murata, Munemasa Mori, Takenori Kotani, Shinya Kusakari, Hideki Okazawa, Hiroshi Ohnishi, and Takashi Matozaki
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  神奈川（パシフィコ横浜）
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] 受容体型チロシンホスファターゼ SAP-1による腸管免疫制御/Regulation of intestinal immunity by the protein tyrosine phosphatase SAP-12013
- Author(s)
  村田陽二, 小谷武徳, Supriatna Yana , 森宗昌, 草苅伸也, 岡澤秀樹, 大西浩史, 的崎尚
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2013-10-03
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] Roles of the protein tyrosine phosphatase Shp2 in homeostasis of the intestinal epithelium2013
- Author(s)
  Takenori Kotani, Hironori Yamashita, Yoji Murata, Hideki Okazawa, Hiroshi Ohnishi, and Takashi Matozaki
- Organizer
  FASEB
- Place of Presentation
  SteamboatSprings, USA
- Data Source
  KAKENHI-PROJECT-25460366
[Presentation] Regulation of intestinal immunity by the protein tyrosine phosphatase SAP-12013
- Author(s)
  村田陽二
- Organizer
  第10回プロテインホスファターゼ国際カンファレンス
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590265
[Presentation] R egulation of brain functions by a protein tyrosine phosphatase Shp22012
- Author(s)
  Kusakari S, Hashimoto M, Hayashi Y, Kusakari Y, Ago Y, Matsuda T, Shibasaki K, Kotani T, Murata Y, Benjamin G. Neel, Matozaki T, Ohnishi H
- Organizer
  平成24年度国際シナプス研究会
- Place of Presentation
  岡崎コンファレンスセンター(愛知)
- Year and Date
  2012-11-08
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] 成熟脳におけるShp 2の生理機能解析2012
- Author(s)
  草苅伸也、村田陽二、的崎尚, 他
- Organizer
  第5回プロテインホスファターゼ研究会学術集会大阪
- Place of Presentation
  大阪大学銀杏会館
- Year and Date
  2012-01-19
- Data Source
  KAKENHI-PROJECT-22590265
[Presentation] 細胞質型チロシンホスファターゼShp2の成熟脳における機能解析/Functional analysis of tyrosine phosphatase Shp2 in the adult brain2012
- Author(s)
  草苅伸也, 橋本美穂, 柴崎貢志, 吾郷由希夫, 松田敏夫, Benjamin G. Neel, 小谷武徳, 村田陽二, 的崎尚, 大西浩史
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場ほか(福岡)
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] 脾臓T細胞の恒常性調節への SIRPα の関与/Signal regulatory protein alpha regulates the homeostasis of T lymphocytes in the spleen2012
- Author(s)
  橋本(佐藤)美穂, 齊藤泰之, 金子哲也, 大西浩史, 草苅伸也, 小谷武徳, 村田陽二, 岡澤秀樹, 的崎尚
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場ほか(福岡)
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] 成熟脳におけるShp2の生理機能解析2012
- Author(s)
  草苅伸也, 小谷武徳, 橋本美穂, 村田陽二, 岡澤秀樹, 吾郷由紀夫, 松田敏夫, Benjamin G. Neel, 的崎尚, 大西浩史
- Organizer
  第5回プロテインホスファターゼ研究会学術集会大阪
- Place of Presentation
  大阪大学銀杏会館(大阪)
- Year and Date
  2012-01-19
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] 腸微絨毛特異的な発現を示す受容体型チロシンホスファターゼSAP-1による腸管免疫制御2012
- Author(s)
  小谷武徳、村田陽二、的崎尚, 他
- Organizer
  第5回ブロテインホスファターゼ研究会学術集会大阪
- Place of Presentation
  大阪大学銀杏会館
- Year and Date
  2012-01-19
- Data Source
  KAKENHI-PROJECT-22590265
[Presentation] 腸微絨毛特異的な発現を示す受容体型チロシンホスファターゼSAP-1による腸管免疫制御2012
- Author(s)
  小谷武徳, 村田陽二, Yana Supriatna, 岡澤秀樹, 大西浩史, Edwin Daniwijaya, 草苅伸也, 定方久延, 大川克也, 的崎尚
- Organizer
  第5回プロテインホスファターゼ研究会学術集会大阪
- Place of Presentation
  大阪大学銀杏会館(大阪)
- Year and Date
  2012-01-19
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] 血管内皮細胞のシェアストレス刺激応答におけるVE-PTPの機能解析2011
- Author(s)
  村田陽二、的崎尚, 他
- Organizer
  群馬大学・秋田大学連携グローバルCOEプログラム「生体調節シグナルの統合的研究」第5回グローバルCOE若手研究者シンポジウム
- Place of Presentation
  秋田キャッスルホテル
- Year and Date
  2011-08-31
- Data Source
  KAKENHI-PROJECT-22590265
[Presentation] 蛋白質チロシンホスファターゼShp2の成熟脳における機能解析2011
- Author(s)
  草苅伸也、村田陽二、的崎尚, 他
- Organizer
  第2回国際放射線神経生物学会大会
- Place of Presentation
  群馬大学刀城会館
- Year and Date
  2011-12-03
- Data Source
  KAKENHI-PROJECT-22590265
[Presentation] 血管内皮細胞のシェアストレス刺激応答におけるVE-PTPの機能解析2011
- Author(s)
  村田陽二、的崎尚, 他
- Organizer
  群馬大学・秋田大学連携グローバルCOEプログラム「生体調節シグナルの統合的研究」第5回グローバルCOE若手研究者シンポジウム
- Place of Presentation
  秋田キャッスルホテル
- Year and Date
  2011-08-31
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] チロシンホスファターゼSAP-1の機能と病態2011
- Author(s)
  岡澤秀樹、村田陽二、的崎尚, 他
- Organizer
  第10回生体機能研究会
- Place of Presentation
  清流の郷ブルーヴィラあなぶき
- Year and Date
  2011-07-30
- Data Source
  KAKENHI-PROJECT-22590265
[Presentation] Dendritic cell-specific depletion of protein tyrosine phosphatase Shp1 promotes Th1 differentiation causes autoimmunity2011
- Author(s)
  Kaneko T., Murata Y, Matozaki, T., et al
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22590265
[Presentation] 血管内皮細胞のシェアストレス刺激応答におけるVE-PTPの機能解析2010
- Author(s)
  村田陽二, 他
- Organizer
  BMB2010 第33回日本分子生物学会年会第83回日本生化学会大会合同年会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22590265
[Presentation] 血管内皮細胞のシェアストレス刺激応答における VE-PTP の機能解析2010
- Author(s)
  村田陽二
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22590265
[Presentation] Tyrosine phosphorylation of SAP-1, a receptor-type protein tyrosine phosphatase, and its association with Grb2.2009
- Author(s)
  Murata, Y., Kotani, Supriatna, Y., Mori, M., Okazawa, H., Ohnishi, H., Saito, Y., Matozaki, T.
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] Tyrosine phosphorylation of SAP-1, a receptor-type protein tyrosine phosphatase, and its association with Grb22009
- Author(s)
  村田陽二、的崎尚, 他
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] Promotion by VE-PTP of lamellipodium formation in cooperation with Ras and integrin.2009
- Author(s)
  M ori, M., Murata, Y., Ohnishi, H., Okazawa, H., Kotani, T., Saito, Y., Mori, M. Matozaki, T.
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] SAP-1 is an intestinal microvillus-specific protein tyrosine phosphatase that protects against colitis in cooperation with IL-102009
- Author(s)
  村田陽二、的崎尚, 他
- Organizer
  第61回日本細胞生物学会大会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] Essential roles of SHPS-1 in homeostasis of dendritic cells2008
- Author(s)
  齋藤泰之、金子和光、岩村紘子、金澤義丈、村田陽二、大西浩史、野島美久、的崎尚
- Organizer
  第10回国際樹状細胞シンポジウム
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] Trans-endocytosis of CD47 and SHPS-1 and its role in regulation of the CD47-SHPS-1 system2008
- Author(s)
  Kusakari S., Ohnishi H., Okazawa H., Murata T., Murata Y., and Matozaki T
- Organizer
  第8回国際プロテインホスファターゼカンファレンス
- Place of Presentation
  前橋テルサ
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] 腸微絨毛特異名発現を示すチロシンホスファターゼSAP-1による腸管腫瘍形成の制御2008
- Author(s)
  定方久延、村田陽二、岡澤秀樹、Yana Supriatna、佐藤隆史、大西浩史、原田彰宏、峯岸敬、的崎尚
- Organizer
  第31回日本分子生物学会年会、第81回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] チロシンホスファターゼによるがん、炎症性腸炎の制御2008
- Author(s)
  的崎尚、岡澤秀樹、村田陽二、大西浩史
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] Defective Development of Dendritic Cells in SHPS-1 Mutant Mice2008
- Author(s)
  Saito Y., Iwamura H., Kanazawa Y., Murata Y., Ohnishi H., Kaneko Y., Nojima Y., and Matozaki T
- Organizer
  第8回国際プロテインホスファターゼカンファレンス
- Place of Presentation
  前橋テルサ
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] クラス3受容体型チロシンホスファターゼの機能と病態への関与2008
- Author(s)
  Yana Supriatna、岡澤秀樹、村田陽二、大西浩史、的崎尚
- Organizer
  第31回日本分子生物学会年会、第81回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] 受容体型チロシンボスファターゼSAP-1のテロシンリン酸化とその生理的意義2008
- Author(s)
  村田陽二、他
- Organizer
  第31回日本分子生物学会年会第81回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] 受容体型膜蛋白質SHPS-1のインスリン分泌制御における機能解析2008
- Author(s)
  小林雅樹、大西浩史、岡澤秀樹、村田陽二、林由里子、北村忠弘、的崎尚
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] SAP-1 is a microvillus-specific protein tyrosine phosphatase that regulates intestinal tumorigenesis.2008
- Author(s)
  S adakata, H., Okazawa, H., Supriatna, Y., Ohnishi, H., Murata, Y., Matozaki, T.
- Organizer
  FASEB Summer Research Conferences
- Place of Presentation
  Snowmass, Colorado(USA)
- Year and Date
  2008-07-13
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] SHPS-1は樹状細胞の恒常性に重要である2008
- Author(s)
  齋藤泰之、金子和光、岩村紘子、金澤義丈、村田陽二、大西浩史、野島美久、的崎尚
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都国際会館
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] CD47とSHPS-1のトランスエンドサイトーシスとCD47-SHPS-1系の制御における役割2008
- Author(s)
  大西浩史、草苅伸也、村田考啓、村田陽二、岡澤秀樹、的崎尚
- Organizer
  第60回日本細胞生物学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] クラス3受容体型チロシンホスファターゼの機能と病態への関与2008
- Author(s)
  Y ana Supriatna、岡澤秀樹、村田陽二、大西浩史、的崎尚
- Organizer
  第31回日本分子生物学会年会第81回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] 受容体型チロシンホスファターゼSAP-1のチロシンリン酸化とその生理的意義2008
- Author(s)
  村田陽二、草苅百合子、三宅敦子、岡澤秀樹、大西浩史、的崎尚
- Organizer
  第31回日本分子生物学会年会、第81回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] チロシンホスファターゼによるがん、炎症性腸炎の制御2008
- Author(s)
  的崎尚、岡澤秀樹、村田陽二、大西浩史
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] SAP-1 is a microvillus-specific protein tyrosine phosphatase that regulates intestinal tumorigenesis2008
- Author(s)
  Sadakata H., Okazawa H., Supriatna Y., Ohnishi H., Murata Y., and Matozaki T
- Organizer
  FASEB Summer Research Conferences
- Place of Presentation
  Snowmass, Colorado, USA
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] 受容体型チロシンボスファターゼSAP-1のチロシンリン酸化とその生理的意義2008
- Author(s)
  村田陽二、的崎尚他
- Organizer
  第31回日本分子生物学会年会, 第81回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] 腸管におけるSHPS-1発現と腸管免疫制御2008
- Author(s)
  金澤義丈、齋藤泰之、ヤナ、スプリアトナ、村田陽二、岡澤秀樹、大西浩史、下瀬川透、的崎尚
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都国際会館
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] Regulation by CD47-SHPS-1 system of neurite development2007
- Author(s)
  Murata T., Ohnishi H., Kusakari S., Murata Y., Okazawa H., Furuya N., and Matozaki T
- Organizer
  Neurosciense 2007
- Place of Presentation
  San Diego Convention center
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] CD47-SHPS-1シグナルシステムの機能とその分子機構2007
- Author(s)
  的崎尚、大西浩史、岡澤秀樹、村田陽二
- Organizer
  第30回日本分子生物学会年会、第80回日本生化学会大会合同大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] Trans-endocytosis of CD47 and SHPS-1 and its molecular mechanism2007
- Author(s)
  大西浩史、草苅伸也、金鋒杰、村田考啓、篠原将彦、村田陽二、岡澤秀樹、的崎尚
- Organizer
  第30回日本神経科学大会第50回日本神経化学会大会第17回日本神経回路学会大会合同大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] SHPS-1によるToll-like receptorを介したサイトカイン産生の制御2007
- Author(s)
  三宅敦子、村田陽二、池田洋、岡澤秀樹、大西浩史、平田結喜緒、的崎尚
- Organizer
  第30回日本分子生物学会年会、第80回日本生化学会大会合同大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] Regulation by CD47-SHPS-1 system of neurite development.2007
- Author(s)
  M urata, T., Ohnishi, H., Kusakari, S., Murata, Y., Okazawa, H., Furuya, N., Matozaki, T.
- Organizer
  Neurosciense 2007
- Place of Presentation
  San Diego Convention center(サンディエゴ)
- Year and Date
  2007-11-03
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] Regulation by SHPS-1 of skin immunity and of Toll-like receptor-mediated cytokine production2007
- Author(s)
  Motegi S., Okazawa H., Kobayashi H., Murata Y., Ohnishi H., Ishikawa O., and Matozaki T
- Organizer
  第37回日本免疫学会総会・学術集会, 第37回日本免疫学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル新高輪
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] Regulations by CD47-SHPS-1 system of neurite development2007
- Author(s)
  村田考啓、大西浩史、草苅伸也、村田陽二、岡澤秀樹、古屋信彦、的崎尚
- Organizer
  第30回日本神経科学大会第50回日本神経化学会大会第17回日本神経回路学会大会合同大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] SHPS-1による皮膚免疫とToll様受容体を介したサイトカイン産生の制御2007
- Author(s)
  茂木精一郎、岡澤秀樹、小林久江、村田陽二、大西浩史、石川治、的崎尚
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] 細胞間シグナルシステムCD47-SHPS-1系による神経突起形成の制御2007
- Author(s)
  村田考啓, 他
- Organizer
  第30回日本神経科学大会・第50回日本神経化学会大会・第17回日本神経回路学会大会合同大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] Roles of SHPS-1 and its family protein SIRPβ in regulation of macrophage phagocytosis2007
- Author(s)
  Okazawa H., Motegi S., Ikeda H., Morimoto N., Ishikawa-Sekigami T., Hayashi A., Murata Y., Ohnishi H., and Matozaki T
- Organizer
  第59回日本細胞生物学会大会第40回日本発生生物学会大会合同大会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] Regulation by CD47-SHPS-1 system of neurite development2007
- Author(s)
  Murata T., et. al.
- Organizer
  37th Annual Meeting, Society for Neuroscience
- Place of Presentation
  San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] Regulation by CD47 of epithelial cell spreading and migration and its signal transduction2007
- Author(s)
  Murata Y., Shinohara M., Morimoto N., Okazawa H., Ohnishi H., and Matozaki T
- Organizer
  EuroPhosphatases 2007
- Place of Presentation
  Aveiro, Portugal
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] Regulation by CD47 of epithelial cell spreading and migration and its signal transduction2007
- Author(s)
  Murata Y., Shinohara M., Morimoto N., Okazawa H., Ohnishi H., Ishikawa O., and Matozaki T
- Organizer
  第59回日本細胞生物学会大会第40回日本発生生物学会大会合同大会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] Trans-endocytosis of CD47-SHPS-1 system and its molecular mechanism.2007
- Author(s)
  K usakari, S., Ohnishi, H., Okazawa, H., Murata, T., Murata, Y., Matozaki, T.
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] An essential role of SHPS-1 in development of Th17-mediated inflammatory autoimmune diseases2007
- Author(s)
  Ohnishi H., Kaneko Y., Okazawa H., Murata Y., and Matozaki T
- Organizer
  EuroPhosphatases 2007
- Place of Presentation
  Aveiro, Portugal
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] Regulation by SHPS-1 of Toll-like receptor-mediated cytokine production in macrophages2007
- Author(s)
  Miyake A., Murata Y., Okazawa H., Ikeda H., Onhishi H., Hirata Y., and Matozaki T
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル新高輪
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] An essential role of SHPS-1 in proper development of dendritic cells for induction of Th17-mediated autoimmune diseases2007
- Author(s)
  Saito Y., Kaneko Y., Kaneko Y., Okuzawa C., Sekigami T., Okajo J., Tomizawa T., Murata Y., Okazawa H., Onhishi H., Matozaki T., and Nojima Y
- Organizer
  第37回日本免疫学会総会・学術集会, 第37回日本免疫学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル新高輪
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] Regulation by CD47-SHPS-1 system of neurite development and its molecular mechanism2007
- Author(s)
  Ohnishi H., Murata T., Miyashita M., Kusakari S., Okazawa H., Murata Y., Itoh H., Furuya N., and Matozaki T
- Organizer
  第59回日本細胞生物学会大会第40回日本発生生物学会大会合同大会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] Regulation by CD47 of epithelial cell spreading and migration and its signal transduction2007
- Author(s)
  Murata Y., et. al.
- Organizer
  第59回日本細胞生物学会大会・第40回日本発生生物学会大会合同大会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-19790205
[Presentation] NKT細胞の活性化と癌転移抑制におけるSHPS-1の役割2006
- Author(s)
  岡上準、金子和光、村田陽二、岡澤秀樹、大西浩史、野島美久、的崎尚, 他
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2006-09-28
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] CD47 promotes neuronal development through Src-and FRG/Vav2-mediated activation of Rac and Cdc42.2006
- Author(s)
  M urata, T., Ohnishi, H., Okazawa, H., Murata, Y., Kusakari, S., Hayashi, Y., Miyashita, M., Furuya, N., Matozaki, T.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2006-06-18
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] A Novel Intercellular Communication System, The CD47-SHPS-1 System, in Neuronal Network.2005
- Author(s)
  Ohnishi, H., Miyashita, M., Murata, T., Kaneko, Y., Okazawa, H., Matozaki, T.
- Organizer
  ISN-ESN:20th Biennial Meeting International Society for Neurochemistry jointly with the European Society for Neurochemistry
- Place of Presentation
  Congress Innsbruck(Innsbruck, Austria)
- Year and Date
  2005-08-25
- Data Source
  KAKENHI-PROJECT-17014010
[Presentation] Hypothermia - dependent and - independent effects of forced swim on the phosphorylation satates of signaling molecules in mouse hippocampus
- Author(s)
  Miho Sato-Hashimoto, Yuriko Hayashi, Shinya Kusakari, Eriko Urano, Masahiro Shigeno, Tsuneo Sekijima, Takenori Kotani, Yoji Murata, Hirokazu Murakami, Takashi Matozaki, Hiroshi Ohnishi
- Organizer
  Neuro 2013
- Place of Presentation
  京都府・国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] 樹状細胞及び二次リンパ組織の恒常性維持におけるＳＩＲＰαの役割
- Author(s)
  鷲尾健、小谷武徳、レスパティカ　ダトゥ、村田陽二、岡澤秀樹、大西浩史、福永淳、錦織千佳子、的崎尚
- Organizer
  第6回日本プロテインホスファターゼ研究会学術集会
- Place of Presentation
  三重県・三重大学
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] Role of VE-PTP in shear stress responses of endothelial cells
- Author(s)
  Isnainiasih Mantilidewi Kemala, Yoji Murata, Munemasa Mori, Takenori Kotani, Shinya Kusakari, Hideki Okazawa, Hiroshi Ohnishi, Takashi Matozaki
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  神奈川県・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] Regulation of intestinal immunity by the protein tyrosine phosphatase SAP-1
- Author(s)
  Murata Y
- Organizer
  第10回プロテインホスファターゼ国際カンファレンス
- Place of Presentation
  東京都・国立がん研究センター
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] Functinal analysis of protein tyrosine phosphatase Shp2 in post-mitotic neurons
- Author(s)
  Shinya Kusakari, Fumihito Saitow, Miho Hashimoato, Yasunori Matsuzaki , Takenori Kotani, Yoji Murata, Hirokazu Hirai, Hidenori Suzuki, Takashi Matozaki, Hiroshi Ohnishi
- Organizer
  第11回プロテインホスファターゼ国際カンファレンス
- Place of Presentation
  東北大学医学部艮陵会館（宮城県・仙台市）
- Year and Date
  2014-11-12 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] SIRPα-CD47 system regulates the homeostasis of dendritic cells in lymphoid tissues
- Author(s)
  Ken Washio, Takenori Kotani, Datu Respatika, Yoji Murata, Hideki Okazawa, Hiroshi Ohnishi, Atsushi Fukunaga, Chikako Nishigori, Takashi Matozaki
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉県・幕張メッセ
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] SIRPα-CD47 system regulates the homeostasis of dendritic cells in lymphoid tissues
- Author(s)
  Ken Washio, Takenori Kotani, Datu Respatika, Yoji Murata, Hideki Okazawa, Hiroshi Ohnishi, Atsushi Fukunaga, Chikako Nishigori, Takashi Matozaki
- Organizer
  ワシントン大学・神戸大学国際合同シンポジウム
- Place of Presentation
  USA・ワシントン大学（シアトル）
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] R3 受容体型チロシンホスファターゼの発現、局在と生理機能
- Author(s)
  的崎尚、村田陽二、小谷武徳、Yana Supriatna、森宗昌、岡澤秀樹、大西浩史
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  兵庫県・神戸国際会議場　他
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] 細胞質型チロシンホスファターゼShp2による脳機能制御
- Author(s)
  草苅伸也、齋藤文仁、橋本美穂、柴崎貢志、吾郷由紀夫、小谷武徳、村田陽二、松田敏夫、Benjamin G. Neel、的崎尚、大西浩史
- Organizer
  第6回日本プロテインホスファターゼ研究会学術集会
- Place of Presentation
  三重県・三重大学
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] SIRPαによる脾臓T細胞の恒常性の調節
- Author(s)
  橋本美穂、齊藤泰之、金子哲也、大西浩史、草苅伸也、小谷武徳、村田陽二、岡澤秀樹、的崎尚
- Organizer
  第60回北関東医学会総会
- Place of Presentation
  群馬県・群馬大学医学部刀城会館
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] 腸上皮の恒常性維持におけるチロシンホスファターゼShp2の役割
- Author(s)
  小谷武徳、山下博成、村田陽二、岡澤秀樹、大西浩史、具英成、的崎尚
- Organizer
  第12回生体機能研究会
- Place of Presentation
  群馬県・ホテル木暮 (伊香保温泉)
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] 樹状細胞及び二次リンパ組織の恒常維持におけるSIRPαの役割
- Author(s)
  鷲尾健、小谷武徳、レスパティカダトゥ、村田陽二、齊藤泰之、金子和光、岡澤秀樹、大西浩史、福永淳、錦織千佳子、的崎尚
- Organizer
  第13回生体機能研究会
- Place of Presentation
  ホテルパーク /岐阜長良川温泉（岐阜県・岐阜市）
- Year and Date
  2014-07-18 – 2014-07-19
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] 腸上皮の恒常性維持におけるチロシンホスファターゼShp2 の役割/Roles of the protein tyrosine phosphatase Shp2 in maintaining homeostasis of the intestinal epithelium
- Author(s)
  山下博成、小谷武徳、村田陽二、岡澤秀樹、大西浩史、具英成、的崎尚
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  神奈川県・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] 腸上皮の恒常性維持におけるチロシンホスファターゼShp2の役割
- Author(s)
  小谷武徳、山下博成、朴貞河、村田陽二、岡澤秀樹、大西浩史、具英成、的崎尚
- Organizer
  第6回日本プロテインホスファターゼ研究会学術集会
- Place of Presentation
  三重県・三重大学
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] 腸上皮の恒常性維持におけるチロシンホスファターゼShp2の役割/Roles of the protein tyrosine phosphatase Shp2 in maintaining homeostasis of the intestinal epithelium
- Author(s)
  小谷武徳、山下博成、村田陽二、岡澤秀樹、大西浩史、具英成、的崎尚
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  神奈川県・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] Role of VE-PTP in shear stress responses of endothelial cells
- Author(s)
  Isnainiasih Mantilidewi Kemala, Yoji Murata, Munemasa Mori, Takenori Kotani, Shinya Kusakari, Hideki Okazawa, Hiroshi Ohnishi, Takashi Matozaki
- Organizer
  ワシントン大学・神戸大学国際合同シンポジウム
- Place of Presentation
  USA・ワシントン大学（シアトル）
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] 細胞質型チロシンホスファターゼShp2の成熟脳における機能解析
- Author(s)
  草苅伸也、橋本美穂、柴崎貢志、吾郷由希夫、松田敏夫、Benjamin G. Neel、小谷武徳、村田陽二、的崎尚、大西浩史
- Organizer
  第60回北関東医学会総会
- Place of Presentation
  群馬県・群馬大学医学部刀城会館
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] 成熟腸上皮細胞の寿命決定の分子基盤/Molecular basis for regulation of the life span of intestinal epithelial cells
- Author(s)
  的崎尚、小谷武徳、村田陽二
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  神奈川県・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] Functional Analysis of A non-receptor type protein tyrosine phosphatase Shp2 in the adult brain
- Author(s)
  Shinya Kusakari, Fumihito Saitow, Miho Sato-Hashimoto, Koji Shibasaki, Yukio Agou, Toshio Matsuda, Benjamin G. Neel, Takenori Kotani, Yoji Murata, Takashi Matozaki, Hiroshi Ohnishi
- Organizer
  Neuro 2013
- Place of Presentation
  京都府・国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] Roles of protein tｙrosine phosphatases in homeostasis of intestinal epithelium
- Author(s)
  Takashi Matozaki, Yoji Murata, Takenori Kotani, Yasuyuki Saito
- Organizer
  第11回プロテインホスファターゼ国際カンファレンス
- Place of Presentation
  東北大学医学部艮陵会館（宮城県・仙台市）
- Year and Date
  2014-11-12 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Essential role of SIRPα on dendritic ｃells in organization and homeostasis of the spleen
- Author(s)
  Ken Washio, Takenori Kotani, Datu Respatika, Yoji Murata, Yasuyuki Saito, Hideki Okazawa, Hiroshi Ohnishi, Atsushi Fukunaga, Chikako Nishigori, Takashi Matozaki
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館（京都府・京都市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Regulation of microglial homeostasis through cell-cell interaction signal
- Author(s)
  Miho Sato-Hashimoto, Yuriko Hayashi, Shinya Kusakari, Takenori Kotani, Yoji Murata, Takashi Matozaki, Hiroshi Ohnishi
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Regulation of intestinal immunity by the protein tyrosine phosphatase SAP-1
- Author(s)
  Murata Y
- Organizer
  第10回プロテインホスファターゼ国際カンファレンス
- Place of Presentation
  東京都・国立がん研究センター
- Data Source
  KAKENHI-PROJECT-22590265
[Presentation] 受容体型チロシンホスファターゼSAP-1 による腸管免疫制御/Regulation of intestinal immunity by the protein tyrosine phosphatase SAP-1
- Author(s)
  村田陽二、小谷武徳、Supriatna Yana 、森宗昌、草苅伸也、岡澤秀樹、大西浩史、的崎尚
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  神奈川県・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23370061
[Presentation] Functional Analysis of protein tyrosine phosphatase Shp2 in the adult forebrain neurons
- Author(s)
  Hiroshi Ohnishi, Shinya Kusakari, Fumihito Saitow, Miho Hashimoto, Yasunori Matsuzaki, Takenori Kotani, Yoji Murata, Hirokazu Hirai, Hidenori Suzuki, Takashi Matozaki
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] 細胞間コミュニケーションシステムCD47-SIRPα系による血液・免疫系の制御 / Regulation by CD47-SIRPα signaling of hematopoietic and immune systems
- Author(s)
  小谷武徳、鷲尾健、ダトゥレスパティカ、村田陽二、齊藤泰之、的崎尚
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26291022

1. MATOZAKI Takashi (80252782)

# of Collaborated Projects: 3 results

# of Collaborated Products: 87 results
2. OHNISHI Hiroshi (70334125)

# of Collaborated Projects: 3 results

# of Collaborated Products: 71 results
3. OKAZAWA Hideki (80334126)

# of Collaborated Projects: 1 results

# of Collaborated Products: 24 results
4. SAITO Yasuyuki (40508842)

# of Collaborated Projects: 1 results

# of Collaborated Products: 22 results
5. KOTANI Takenori (40455960)

# of Collaborated Projects: 1 results

# of Collaborated Products: 23 results
6. 宮坂昌之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Murata Yoji 村田 陽二

MURATA Yoji 村田 陽二

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Co-Researchers

がん微小環境でのがん免疫監視における自然免疫細胞の機能的役割とその作用機構の解明Principal Investigator

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がん微小環境における細胞間シグナルによる腫瘍免疫制御Principal Investigator

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Molecular mechanisms underlying an immune evasion by cancer cells via cell-to-cell signalingPrincipal Investigator

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Regulation of intestinal immunity by an intestinal epithelial-specific protein tyrosine phosphatasePrincipal Investigator

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Molecular basis of the CD47-SIRP alpha signaling system in the regulation of physiological function

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Regulation of intestinal immunity by a gastrointestinal epithelial-specific protein tyrosine phosphatase and its pathological role.Principal Investigator

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The integrative research for regulation by protein tyrosine phosphatases of biological functions and its molecular mechanism

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Role of SAP-1,a gastrointestinal-specific protein tyrosine phosphatasePrincipal Investigator

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Molecular mechanism underlying the apical sorting of membrane proteins in epithelial cellsPrincipal Investigator

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神経細胞の極性形成におけるRap1の作用機構と生理機能Principal Investigator

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Protein tyrosine phosphatases and regulation of cancer cell adhesion/migration

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[Journal Article] Preclinical evaluation of the efficacy of an antibody to human SIRPα for cancer immunotherapy in humanized mouse models2023

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[Journal Article] CD47 promotes peripheral T cell survival by preventing dendritic cell?mediated T cell necroptosis2023

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Murata Yoji 村田陽二

MURATA Yoji 村田陽二

[Journal Article] 【プロテインホスファターゼの最先端:制御機構から医療まで】受容体型チロシンホスファターゼの機能と病態　R3サブタイプチロシンホスファターゼを中心に(解説/特集)2015