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Akiyama Haruhiko  秋山 治彦

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… Alternative Names

AKIYAMA Haruhiko  秋山 治彦

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Researcher Number 60402830
Other IDs
Affiliation (Current) 2022: 岐阜大学, 大学院医学系研究科, 教授
Affiliation (based on the past Project Information) *help 2016 – 2022: 岐阜大学, 大学院医学系研究科, 教授
2013 – 2016: 岐阜大学, 医学(系)研究科(研究院), 教授
2014: 岐阜大学, 医学部, 教授
2011 – 2012: 京都大学, 医学(系)研究科(研究院), 准教授
2007 – 2012: Kyoto University, 医学研究科, 准教授 … More
2011: 京都大学, 医学研究所, 准教授
2009: 京都大学, 医学(系)研究科(研究院), 准教授
2008: Kyoto University, 大学院・医学研究科, 准教授
2007 – 2008: 京都大学, 医学研究科, 特任准教授
2005 – 2006: 京都大学, 医学研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Orthopaedic surgery / Basic Section 56020:Orthopedics-related
Except Principal Investigator
Basic Section 56020:Orthopedics-related / Orthopaedic surgery / Rehabilitation science/Welfare engineering / Endocrinology / General surgery / Kidney internal medicine / Rehabilitation science/Welfare engineering / Functional basic dentistry / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords
Principal Investigator
遺伝子改変マウス / ノックアウトマウス / Sox9 / 骨細胞 / イオンチャネル / 廃用性骨萎縮 / 嫌気性代謝 / HA / 新規分泌蛋白質 / 骨特異的 … More / トランスジェニックマウス / HA4 / 核蛋白 / 転写コンプレックス / 転写制御 / 変形性関節症 / メカノセンサー / マイクロアレイ / カリウムチャネル / 骨萎縮 / 骨格形成 / エネルギー代謝 / ミトコンドリア / 骨軟骨形成 / 好気性 / 嫌気性 / Tfam / LDHA / AMPK / 好気性ATP生合成 / 嫌気性ATP生合成 / 骨軟骨 / 乳酸脱水素酵素A / ATP / 骨格 / ATP生合成 / 軟骨 / 創薬スクリーニング … More
Except Principal Investigator
変形性関節症 / 軟骨細胞 / 関節軟骨 / 変形性膝関節症 / PI3K/Aktシグナル / Sox9 / メカニカルストレス / 低分子ヘパリン / drug delivery system / 未分化Schwann細胞 / 末梢神経再生 / 末梢神経損傷 / 再生医療 / SAMP6 / SAMP2 / osteoporosis / congenic / Sfrp4 / osteoblast / CNP / GC-B / 骨伸長 / 軟骨無形成症 / 展開研究 / 骨系統疾患 / 成体臓器維持機 / 幹細胞 / 肝前駆細胞 / 膵前駆細胞 / 腸管幹細胞 / 膵臓 / 肝臓 / 転写因子 / 骨芽細胞分化 / オステリクス / ヘミチャネル / 糖尿病性腎症 / Smad1 / BMP4 / 軟骨細胞様形質変化 / 不可逆的腎機能低下 / ALK3/6 / Scleraxis / HIF1 / ALK3 / 6 / 超音波 / 刺激 / 活性 / 超音波刺激 / 活性化 / ルブリシン / Prg4 / メカノセンシング / 関節表層遺伝子 / 遺伝子改変マウス / PRG4 / 関節表層 / マイクロアレイ / 潤滑機能 / 変形性股関節症 / 歩行 / 進行 / 負荷 / 動作特性 / 動作解析 / リハビリテーション / 物理的刺激 / 発生・分化 / 腱 / 靭帯 / 硬組織 / 遺伝子改変動物 / ゲノム編集 / 靱帯 / 顎関節 / 発生・分化 / 明細胞肉腫 / EWS/ATF1 / iPS細胞 / 起源細胞 / ヘパラン硫酸 / Ext1 / 骨・軟骨代謝学 / ヒアルロン酸 / 未分化Schwann 細胞 / Wntシグナル / iPS 細胞 / 腱損傷 / 腱細胞 / PI3K/Akt / 骨粗鬆症治療 / 高硫酸化糖鎖 / ホスホリパーゼC / 病態修飾性治療薬 / MMP13 / 骨折 / 再生治療 / シュワン細胞 / 脊椎関節炎 / アキレス腱付着部炎 / 骨新生 / シグナル経路 / 付着部炎 / Wnt /β-catenin シグナル / 脱分化 / PI3K/Akt シグナル / Wnt/β-catenin シグナル Less
  • Research Projects

    (30 results)
  • Research Products

    (41 results)
  • Co-Researchers

    (42 People)
  •  Functional analysis of anaerobic metabolism in cartilage and drug discovery for cartilage disordersPrincipal Investigator

    • Principal Investigator
      秋山 治彦
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Gifu University
  •  ペプチド修飾による骨指向性多硫酸化糖鎖を使った新規骨粗鬆症治療の開発

    • Principal Investigator
      山田 一成
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Gifu University
  •  変形性膝関節症の治療標的としてのホスホリパーゼCガンマの機能解析

    • Principal Investigator
      小川 寛恭
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Gifu University
  •  骨折治癒部位に誘導されるシュワン細胞と間葉系骨形成細胞の細胞間情報伝達機構の解明

    • Principal Investigator
      河村 真吾
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Gifu University
  •  低分子ヘパリンを用いた骨DDSの開発と骨再生研究

    • Principal Investigator
      野澤 聡
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Gifu University
  •  PI3K/Akt腱再生シグナルの解明による新規腱再生治療法の開発

    • Principal Investigator
      河村 真吾
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Gifu University
  •  脊椎関節炎における付着部炎と骨新生に関する新規シグナル探索と治療への応用

    • Principal Investigator
      田中 領
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Gifu University
  •  シュワン細胞脱分化機構の解明と未分化シュワン細胞誘導による末梢神経再生の研究

    • Principal Investigator
      平川 明弘
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Gifu University
  •  The Development of system for drug delivery to the bones using low molecular weight heparin to promote bone regeneration

    • Principal Investigator
      Nozawa Satoshi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Gifu University
  •  The role of hyaluronic acid in osteoarthritis

    • Principal Investigator
      Matsumoto Kazu
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Gifu University
  •  Investigation of new treatment of the peripheral nerve injury using of induced pluripotent stem cell induced immature Schwann cells

    • Principal Investigator
      Hirakawa Akihiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Gifu University
  •  The study for ATP biosynthesis in skeletal development and skeletal disordersPrincipal Investigator

    • Principal Investigator
      Akiyama Haruhiko
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Gifu University
  •  Identification of the cell-of-origin of clear cell sarcoma utilizing iPS cell technology and development of novel molecular therapy

    • Principal Investigator
      Ohno Takatoshi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Gifu University
  •  The role of heparan sulfate in osteoarthritis

    • Principal Investigator
      Matsumoto Kazu
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Gifu University
  •  Molecular analysis of mechanical stress response in joint formation

    • Principal Investigator
      Takigami Iori
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Gifu University
  •  Mechanisms underlying formation of tissue domains integrating the skeletal components

    • Principal Investigator
      Shukunami Chisa
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Hiroshima University
  •  effect of rehabilitation using mechanical stimuli on articular cartilage and chondrocyte

    • Principal Investigator
      Kuroki Hiroshi
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Rehabilitation science/Welfare engineering
    • Research Institution
      Kyoto University
  •  The analysis of potassium channel as mechanosensors in osteocytesPrincipal Investigator

    • Principal Investigator
      AKIYAMA HARUHIKO
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Gifu University
  •  Investigation of molecular and mechanosensitive mechanisms on lubricin-targeted gene expression specific to the surface of joint

    • Principal Investigator
      YAMAMOTO KOJI
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto University
  •  Cohort study on relationship between gait characteristics and progression of hip osteoarthritis toward development of approach for hip osteoarthritis prevention

    • Principal Investigator
      Tateuchi Hiroshige
    • Project Period (FY)
      2012 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Rehabilitation science/Welfare engineering
    • Research Institution
      Kyoto University
  •  A study of bone atrophy treatment by detection of factors in osteocytes involved in mechanical stressPrincipal Investigator

    • Principal Investigator
      AKIYAMA Haruhiko
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto University
  •  Effect of Ultrasound on Viability of Chondrocyte

    • Principal Investigator
      KUROKI Hiroshi
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Rehabilitation science/Welfare engineering
    • Research Institution
      Kyoto University
  •  Studies of pathological involvement of Sox9 in osteoarthritis and discovery of new treatment for osteoarthritisPrincipal Investigator

    • Principal Investigator
      AKIYAMA Haruhiko
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto University
  •  転写因子ソックス9を指標とした成体肝・膵・腸管幹細胞同定の試み

    • Principal Investigator
      川口 義弥
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Kyoto University
  •  新規骨特異的チャネル分子パネキシン3の骨形成における機能解析

    • Principal Investigator
      前田 真吾
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kagoshima University
  •  Molecular mechanisms for irreversible phenotypic changes leading to renal failure in chronic kidney diseases.

    • Principal Investigator
      ABE Hideharu
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokushima
  •  新規SOX9結合核蛋白質の機能解析Principal Investigator

    • Principal Investigator
      秋山 治彦
    • Project Period (FY)
      2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto University
  •  Translational Research of the CNP/GC-B system for Skeletal dysplasias

    • Principal Investigator
      YASODA Akihiro
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      Kyoto University
  •  Basic analysis and clinical usage of a bone-specific secreted protein, HA4Principal Investigator

    • Principal Investigator
      AKIYAMA Haruhiko
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto University
  •  マウス第13染色体における骨量制御候補遺伝子Tbceの解析

    • Principal Investigator
      中村 孝志
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyoto University

All 2017 2016 2015 2014 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation

  • [Journal Article] Daily cumulative hip moment is associated with radiographic progression of secondary hip osteoarthritis2017

    • Author(s)
      Tateuchi H, Koyama Y, Akiyama H, Goto K, So K, Kuroda Y, Ichihashi N
    • Journal Title

      Osteoarthritis Cartilage

      Volume: 25 Pages: 1291-1298

    • DOI

      10.1016/j.joca.2017.02.796

    • NAID

      120006534626

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500578
  • [Journal Article] Radiographic and clinical factors associated with one-leg standing and gait in patients with mild-to-moderate secondary hip osteoarthritis2016

    • Author(s)
      Tateuchi H, Koyama Y, Akiyama H, Goto K, So K, Kuroda Y, Ichihashi N.
    • Journal Title

      Gait and Posture

      Volume: 49 Pages: 207-212

    • DOI

      10.1016/j.gaitpost.2016.07.018

    • NAID

      120005868489

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24500578
  • [Journal Article] Associations of radiographic degeneration and pain with daily cumulative hip loading in patients with secondary hip osteoarthritis2016

    • Author(s)
      Tateuchi H, Koyama Y, Tsukagoshi R, Akiyama H, Goto K, So K, Kuroda Y, Ichihashi N.
    • Journal Title

      Journal of Orthopaedic Research

      Volume: in press

    • DOI

      10.1002/jor.23223

    • NAID

      120005749956

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24500578
  • [Journal Article] Contributions of biarticular myogenic components to the limitation of the range of motion after immobilization of rat knee joint.2014

    • Author(s)
      Nagai M, Aoyama T, Ito A, Iijima H, Yamaguchi S, Tajino J, Zhang X, Akiyama H, Kuroki H.
    • Journal Title

      BMC Musculoskelet Disord

      Volume: 15 Pages: 224-224

    • DOI

      10.1186/1471-2474-15-224

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25242055
  • [Journal Article] Optimum temperature for extracellular matrix production by articular chondrocytes.2014

    • Author(s)
      Akira Ito, Tomoki Aoyama, Hirotaka Iijima, Momoko Nagai, Shoki Yamaguchi, Junichi Tajino, Xiangkai Zhang, Haruhiko Akiyama, Hiroshi Kuroki
    • Journal Title

      Int J Hyperthermia

      Volume: 30 Pages: 96-101

    • DOI

      10.3109/02656736.2014.880857

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J03611, KAKENHI-PROJECT-23300199, KAKENHI-PROJECT-25242055
  • [Journal Article] Evaluation of reference genes for human chondrocytes cultured in several different thermal environments.2014

    • Author(s)
      Akira Ito, Tomoki Aoyama, Junichi Tajino, Momoko Nagai, Shoki Yamaguchi, Hirotaka Iijima, Xiangkai Zhang, Haruhiko Akiyama, Hiroshi Kuroki
    • Journal Title

      Int J Hyperthermia

      Volume: 30 Pages: 210-216

    • DOI

      10.3109/02656736.2014.906048

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J03611, KAKENHI-PROJECT-25242055
  • [Journal Article] Effects of the thermal environment on articular chondrocyte metabolism: a fundamental study to facilitate establishment of an effective thermotherapy for osteoarthritis.2014

    • Author(s)
      Ito A, Aoyama T, Tajino J, Nagai M, Yamaguchi S, Iijima H, Zhang X, Akiyama H, Kuroki H.
    • Journal Title

      J Jpn Phys Ther Assoc

      Volume: 17 Pages: 14-21

    • NAID

      130004850398

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25242055
  • [Journal Article] Destabilization of the medial meniscus leads to subchondral bone defects and site-specific cartilage degeneration in an experimental rat model.2014

    • Author(s)
      Iijima H, Aoyama T, Ito A, Tajino J, Nagai M, Zhang X, Yamaguchi S, Akiyama H, Kuroki H.
    • Journal Title

      Osteoarthritis Cartilage

      Volume: 22 Pages: 1036-43

    • DOI

      10.1016/j.joca.2014.05.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25242055
  • [Journal Article] Immature articular cartilage and subchondral bone covered by menisci are potentially susceptive to mechanical load.2014

    • Author(s)
      Iijima H, Aoyama T, Ito A, Tajino J, Nagai M, Zhang X, Yamaguchi S, Akiyama H, Kuroki H.
    • Journal Title

      BMC Musculoskelet Disord

      Volume: 15 Pages: 101-101

    • DOI

      10.1186/1471-2474-15-101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25242055
  • [Journal Article] 低出力超音波パルス療法が関節軟骨代謝に与える即時的影響~異なる刺激強度を用いた研究~2012

    • Author(s)
      伊藤明良、青山朋樹、山口将希、秋山治彦、黒木裕士
    • Journal Title

      理学療法学

      Volume: 39(印刷中)

    • Data Source
      KAKENHI-PROJECT-22650129
  • [Journal Article] Generation of transgenic mice for conditional overexpression of Sox92011

    • Author(s)
      Youngwoo Kim, Hiroki Murao, Haruhiko Akiyama., et al.
    • Journal Title

      J Bone Miner Metab

      Volume: 29(1) Pages: 123-129

    • NAID

      10029023999

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249078
  • [Journal Article] Continuous cell supply from a Sox9-expressing progenitor zone in adultliver, exocrine pancreas and intestine2011

    • Author(s)
      Furuyama K, Kawaguchi Y, Akiyama H, et al.
    • Journal Title

      Nature Genetics

      Volume: 43 Pages: 34-41

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390358
  • [Journal Article] SOX9 protein induces a chondrogenic phenotype of mesangial cells and contributes to advanced diabetic nephropathy2011

    • Author(s)
      Kishi S, Abe H, Akiyama H, Tominaga T, Murakami T, Mima A, Nagai K, Kishi F, Matsuura M, Matsubara T, Iehara N, Ueda O, Fukushima N, Jishage KI, Doi T.
    • Journal Title

      Jbiol Chem

      Volume: 286(37) Pages: 32162-32169

    • DOI

      10.1074/jbc.m111.244541

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591032, KAKENHI-PROJECT-21591033, KAKENHI-PROJECT-21790808, KAKENHI-PROJECT-22390169
  • [Journal Article] Sox9-expressing Prectusors are the Cellular Origin of the Cruciate Ligament of the Knee Joint and the Limb Tendons2010

    • Author(s)
      Tsunemitsu Soeda, Jian Min Deng, Haruhiko Akiyama., et al.
    • Journal Title

      Genesis

      Volume: 48(11) Pages: 635-644

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249078
  • [Journal Article] Cthrc1 is a positive regulator of osteoblastic bone formation2008

    • Author(s)
      Kimura H, Kwan KM, Zhang Z, Deng JM, Darnay BG, Behringer RR, Nakamura T, de Crombrugghe B, Akiyama H
    • Journal Title

      PLoS ONE 9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390413
  • [Journal Article] Cthrcl is a positive regulator of osteoblastic bone formation.2008

    • Author(s)
      Kimura H, Kwan KM, Zhang Z, Deng JM, Darnay BG, Behringer RR, Nakamura T, de Crorabrugghe B. Akiyama H.
    • Journal Title

      PLoS ONE 3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390413
  • [Journal Article] Soxファミリーによる軟骨分化制御2006

    • Author(s)
      秋山治彦
    • Journal Title

      Clinical Calcium 16(2)

      Pages: 144-148

    • Data Source
      KAKENHI-PROJECT-18390413
  • [Journal Article] 軟骨研究の流れ2006

    • Author(s)
      秋山治彦
    • Journal Title

      THE BONE 20(5)

      Pages: 593-597

    • Data Source
      KAKENHI-PROJECT-18390413
  • [Journal Article] Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors.2005

    • Author(s)
      Akiyama H, Kim JE, Nakashima K, Balmes G, Iwai N, Deng JM, Zhang Z, Martin JF, Behringer RR, Nakamura T, Crombrugghe B.
    • Journal Title

      Proc.Nat'l Acad.Sci 102(41)

      Pages: 14665-14670

    • Data Source
      KAKENHI-PROJECT-16659408
  • [Journal Article] Transforming growth factor-beta(1) mediates the effects of low-intensity pulsed ultrasound in chondrocytes2005

    • Author(s)
      Mukai S, Ito H, Nakagawa Y, Akiyama H, Miyamoto M, Nakamura T.
    • Journal Title

      Ultrasound Med Biol. 31(12)

      Pages: 1713-1721

    • Data Source
      KAKENHI-PROJECT-16659408
  • [Journal Article] Interactions between Sox9 and beta-catenin control chondrocyte differentiation2004

    • Author(s)
      Akiyama H., et al.
    • Journal Title

      Genes Dev. 18(9)

      Pages: 1072-87

    • Data Source
      KAKENHI-PROJECT-16659408
  • [Presentation] 股関節累積負荷の増大は変形性股関節症の進行に影響を与える2017

    • Author(s)
      建内宏重, 小山優美子, 秋山治彦, 後藤公志, 宗和隆, 黒田隆, 市橋則明
    • Organizer
      第52回日本理学療法学術大会
    • Data Source
      KAKENHI-PROJECT-24500578
  • [Presentation] Daily cumulative hip load is associated with radiographic progression of secondary hip osteoarthritis2017

    • Author(s)
      Tateuchi H, Koyama Y, Akiyama H, Goto K, So K, Kuroda Y, Ichihashi N.
    • Organizer
      World congress on osteoarthritis 2017
    • Place of Presentation
      Las Vegas
    • Year and Date
      2017-04-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24500578
  • [Presentation] Daily cumulative hip load is associated with radiographic progression2017

    • Author(s)
      Tateuchi H, Koyama Y, Akiyama H, Goto K, So K, Kuroda Y, Ichihashi N
    • Organizer
      OARSI2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24500578
  • [Presentation] 脊柱のアライメントと柔軟性は変形性股関節症の進行に影響を与える2017

    • Author(s)
      建内宏重, 小山優美子, 秋山治彦, 後藤公志, 宗和隆, 黒田隆, 市橋則明
    • Organizer
      第5回日本運動器理学療法学会
    • Data Source
      KAKENHI-PROJECT-24500578
  • [Presentation] 股関節累積負荷の増大は変形性股関節症の進行に影響を与える ―前向きコホート研究による分析―2017

    • Author(s)
      建内宏重、小山優美子、秋山治彦、後藤公志、宗和隆、黒田隆、市橋則明
    • Organizer
      第52回日本理学療法学術大会
    • Place of Presentation
      幕張
    • Year and Date
      2017-05-12
    • Data Source
      KAKENHI-PROJECT-24500578
  • [Presentation] 変形性股関節症患者において股関節累積負荷を増加させる要因2016

    • Author(s)
      建内宏重, 小山優美子, 秋山治彦, 後藤公志, 宗和隆, 黒田隆, 市橋則明
    • Organizer
      第3回日本運動器理学療法学会学術集会
    • Place of Presentation
      金沢
    • Year and Date
      2016-12-03
    • Data Source
      KAKENHI-PROJECT-24500578
  • [Presentation] 前期から進行期の変形性股関節症患者における関節形態および変性変化と股関節可動域・筋力の関連性2015

    • Author(s)
      建内宏重、小山優美子、塚越累、秋山治彦、後藤公志、宗和隆、黒田隆、市橋則明
    • Organizer
      第42回日本股関節学会
    • Place of Presentation
      大阪
    • Year and Date
      2015-10-30
    • Data Source
      KAKENHI-PROJECT-24500578
  • [Presentation] EWS/ATF1誘導性肉腫細胞株由来iPS細胞を用いた発がん研究2015

    • Author(s)
      河村真吾 秋山治彦 大野貴敏 山田一成 戸口田淳也 山田泰広
    • Organizer
      第30回日本整形外科学会基礎学術集会
    • Place of Presentation
      富山国際会議場
    • Year and Date
      2015-10-22
    • Data Source
      KAKENHI-PROJECT-15K10437
  • [Presentation] 腱・靭帯と骨格の付着部を形成する細胞の分化と系譜解析2014

    • Author(s)
      滝本晶,吉本由紀,秋山治彦,開祐司,宿南知佐
    • Organizer
      第15回運動器科学研究会
    • Place of Presentation
      東京都港区、ベルサール三田
    • Year and Date
      2014-09-05
    • Data Source
      KAKENHI-PROJECT-26293395
  • [Presentation] 低出力超音波パルスは軟骨細胞に対しIL-1βによって惹起されたMMP13 mRNA発現を強度依存的に抑制する2012

    • Author(s)
      伊藤明良, 黒木裕士, 張項凱, 秋山治彦
    • Organizer
      第15回超音波骨折治療研究会
    • Place of Presentation
      東京ステーションコンファレンス(東京都)
    • Year and Date
      2012-01-21
    • Data Source
      KAKENHI-PROJECT-22650129
  • [Presentation] IL-1βにより惹起されたMMP13mRNA発現亢進に対する低出力超音波パルスの即時的効果2012

    • Author(s)
      伊藤明良, 山口将希, 張項凱, 青山朋樹, 秋山治彦, 黒木裕士
    • Organizer
      第25回日本軟骨代謝学会
    • Place of Presentation
      ウイルあいち(愛知県)
    • Year and Date
      2012-03-09
    • Data Source
      KAKENHI-PROJECT-22650129
  • [Presentation] 低出力超音波パルスは軟骨細胞に対しIL-1βによって惹起されたMMP13mRNA発現を強度依存的に抑制する2012

    • Author(s)
      伊藤明良, 黒木裕士, 張項凱, 秋山治彦
    • Organizer
      第15回超音波骨折治療研究会
    • Place of Presentation
      東京ステーションコンファレンス(東京都)
    • Year and Date
      2012-01-21
    • Data Source
      KAKENHI-PROJECT-22650129
  • [Presentation] TRPV4 はSox9 の発現を介して変形性関節症の発症を抑制する.2012

    • Author(s)
      山本 浩司, 金 永優, 武井 大輔, 村尾浩樹, 末吉 達也, 塚中 真佐子, 水野 敦子, 鈴木 誠, 松田 秀一, 秋山 治彦
    • Organizer
      第27回日本整形外科学会基礎学術集会
    • Place of Presentation
      名古屋市
    • Year and Date
      2012-10-27
    • Data Source
      KAKENHI-PROJECT-21249078
  • [Presentation] 軟骨における転写制御機構から病態解析・治療へ2010

    • Author(s)
      秋山治彦
    • Organizer
      第28回日本骨代謝学会学術集会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Year and Date
      2010-07-22
    • Data Source
      KAKENHI-PROJECT-21249078
  • [Presentation] Chondrogenic Potential of Mesangial Cells in Diabetic Nephropathy2009

    • Author(s)
      Kishi S, Abe H, Akiyama H, Doi T
    • Organizer
      49th The American Society for Cell Biology Annual Meeting
    • Place of Presentation
      San Diego, U.S.A.
    • Data Source
      KAKENHI-PROJECT-21591033
  • [Presentation] 生後の骨量調節における遺伝子HA4の解析2008

    • Author(s)
      木村浩明、秋山治彦、金永優、小田竜治、添田恒光、村尾浩樹、中村孝志
    • Organizer
      第26回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-18390413
  • [Presentation] 遺伝子HA4は骨芽細胞性骨形成を促進することにより生後骨量を増加させる2008

    • Author(s)
      木村浩明、秋山治彦、小田竜治、金永優、添田恒光
    • Organizer
      第23回日本整形外科学会基礎学術集会
    • Place of Presentation
      京都
    • Year and Date
      2008-10-23
    • Data Source
      KAKENHI-PROJECT-18390413
  • [Presentation] A new secreted protein HA4 is involved in osteoblastic bone formation2007

    • Author(s)
      Haruhiko Akiyama
    • Organizer
      4th Meeting of Bone Biology Forum
    • Place of Presentation
      大阪
    • Year and Date
      2007-08-25
    • Data Source
      KAKENHI-PROJECT-18390413
  • [Presentation] A new secreted protein HA4 is involved in osteoblastic bone formation2007

    • Author(s)
      Haruhiko Akiyama
    • Organizer
      4th Meeting of Bone Biology Forum
    • Place of Presentation
      静岡
    • Year and Date
      2007-08-25
    • Data Source
      KAKENHI-PROJECT-18390413
  • [Presentation] 前期から進行期変形性股関節症患者における関節裂隙狭小化と歩行特性との関連性

    • Author(s)
      建内宏重、小山優美子、塚越累、宗和隆、黒田隆、後藤公志、秋山治彦、市橋則明
    • Organizer
      第50回日本理学療法学術大会
    • Place of Presentation
      東京
    • Year and Date
      2015-06-05 – 2015-06-07
    • Data Source
      KAKENHI-PROJECT-24500578
  • 1.  河村 真吾 (30456511)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 1 results
  • 2.  Nozawa Satoshi (20771679)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  Hirakawa Akihiro (50422720)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  小川 寛恭 (70464104)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  YASODA Akihiro (50378642)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  KUROKI Hiroshi (20170110)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 7.  Shukunami Chisa (60303905)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 8.  Matsumoto Kazu (40422711)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  ITO Hiromu (70397537)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ABE Hideharu (60399342)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 11.  KISHI Seiji (10519507)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 12.  MIURA Mikiko (40447925)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  YAMAMOTO KOJI (70536565)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  TSUMAKI Noriyuki (50303938)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  Tateuchi Hiroshige (60432316)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 16.  Ohno Takatoshi (60281052)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 17.  Takigami Iori (90610410)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  中村 孝志 (10201675)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 19.  清水 基行 (10343229)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  川口 義弥 (60359792)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 21.  前田 真吾 (60353463)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  今村 健志 (70264421)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  市橋 則明 (50203104)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 24.  伊藤 明良 (50762134)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 25.  青山 朋樹 (90378886)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 26.  長井 桃子 (50755676)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 27.  松田 秀一 (40294938)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  滝本 晶 (00378902)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 29.  永野 昭仁 (60422721)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  山田 一成 (90422724)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  田中 領 (70422722)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  GERD SCHERER
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  RALF KIST
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  Yamada Yasuhiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 35.  TOMINAGA Tatsuya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  MATSUURA Motokazu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  MATSUBARA Takeshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  NAGAI Kojiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 39.  MIMA Akira
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 40.  村上 太一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  家原 典之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  土井 俊夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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