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kurose makoto  黒瀬 誠

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… Alternative Names

黒瀬 誠  クロセ マコト

KUROSE Makoto  黒瀬 誠

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Researcher Number 60404696
Affiliation (Current) 2025: 札幌医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2022 – 2023: 札幌医科大学, 医学部, 准教授
2022 – 2023: 札幌医科大学, 医学部, 講師
2012 – 2017: 札幌医科大学, 医学部, 講師
2010 – 2011: 札幌医科大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related
Except Principal Investigator
Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology / Radiation science
Keywords
Principal Investigator
特異的免疫反応 / テロメラーゼ遺伝子導入培養ヒト粘膜上皮細胞 / 樹状細胞 / 分子標的治療薬 / バイオマーカー / タイトジャンクション / 免疫療法 / 頭頸部癌 / NF-kBシグナル / HDAC阻害剤 … More / シグナル伝達経路 / 悪性化 / 頭頸部扁平上皮癌 / malignancy / HDAC / p63/GATA-3 / JAM-A / squamous cell carcinomas / Head and neck cancer / 抗原取り込み機構 / M細胞 / テロメラーゼ遺伝子導入 / 舌下免疫療法 / 特異的免疫療法 … More
Except Principal Investigator
HDAC阻害剤 / タイト結合分子 / p63陽性唾液腺癌 / RSウィルス / 自然免疫 / RS ウイルス / ハウスキーピング / reference microRNA / プラーク法 / housekeeping gene / microRNA / 鼻汁 / IRF-3 / クラリスロマイシン / III型インターフェロン / RSウイルス / 頭頸部がん / IVIM / ADC / 頭頸部癌 / 再現性 / 予後 / 治療効果 / 腫瘍 / DWI / MRI Less
  • Research Projects

    (7 results)
  • Research Products

    (33 results)
  • Co-Researchers

    (20 People)
  •  頭頸部扁平上皮癌における転写因子p63/タイト結合分子JAM-Aの発現解析Principal Investigator

    • Principal Investigator
      黒瀬 誠
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Sapporo Medical University
  •  p63陽性唾液腺癌の新規病態メカニズム解明と治療法の開発

    • Principal Investigator
      小幡 和史
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Sapporo Medical University
  •  Usefulness of disease-specific microRNA for respiratory syncytial virus induced lower respiratory tract inflammation

    • Principal Investigator
      Yamamoto Keisuke
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Sapporo Medical University
  •  Auxiliary diagnosis and molecular targeted therapy by tight junction related molecule JAM-A in head and neck cancerPrincipal Investigator

    • Principal Investigator
      MAKOTO KUROSE
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Sapporo Medical University
  •  Predicting treatment effect and prognosis by using IVIM

    • Principal Investigator
      Hatakenaka Masmaitsu
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Sapporo Medical University
  •  Regulation mechanism of antigen recognition by the interaction control of M cells and intraepithelial dendritic cells and mucosal epitheliumPrincipal Investigator

    • Principal Investigator
      KUROSE Makoto
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Sapporo Medical University
  •  Regulation mechanism of antigen recognition by controlling the interaction of dendritic cells and mucosal cells in the epitheliumPrincipal Investigator

    • Principal Investigator
      KUROSE Makoto
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Sapporo Medical University

All 2023 2017 2016 2015 2014 2013 2012 2011

All Journal Article Presentation Book

  • [Book] 上気道炎症における鼻粘膜の役割2013

    • Author(s)
      黒瀬 誠
    • Total Pages
      13
    • Publisher
      アイワード札幌
    • Data Source
      KAKENHI-PROJECT-24791794
  • [Book] 上気道炎症における鼻粘膜の役割2012

    • Author(s)
      黒瀬誠
    • Publisher
      アイワード札幌
    • Data Source
      KAKENHI-PROJECT-24791794
  • [Journal Article] CXCL12 is expressed by skeletal muscle cells in tongue oral squamous cell carcinoma.2023

    • Author(s)
      Yorozu A, Sekiguchi S, Takasawa A, Okazaki F, Niinuma T, Kitajima H, Yamamoto E, Kai M, Toyota M, Hatanaka Y, Nishiyama K, Ogi K, Dehari H, Obata K, Kurose M, Kondo A, Osanai M, Miyazaki A, Takano K, Suzuki H.
    • Journal Title

      Cancer Med.

      Volume: 12 Issue: 5 Pages: 5953-5963

    • DOI

      10.1002/cam4.5392

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07985, KAKENHI-PROJECT-21K16846, KAKENHI-PROJECT-22K17188, KAKENHI-PROJECT-20K07409, KAKENHI-PROJECT-23K24186, KAKENHI-PROJECT-22K09687, KAKENHI-PROJECT-23K06445
  • [Journal Article] 甲状腺部分切除術 反回神経・副甲状腺の機能温存(解説).2023

    • Author(s)
      黒瀬誠
    • Journal Title

      頭頸部外科

      Volume: 32(3) Pages: 221-226

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K09687
  • [Journal Article] ACLP Activates Cancer-Associated Fibroblasts and Inhibits CD8+ T-Cell Infiltration in Oral Squamous Cell Carcinoma2023

    • Author(s)
      Sekiguchi Shohei、Yorozu Akira、Okazaki Fumika、Niinuma Takeshi、Takasawa Akira、Yamamoto Eiichiro、Kitajima Hiroshi、Kubo Toshiyuki、Hatanaka Yui、Nishiyama Koyo、Ogi Kazuhiro、Kai Masahiro、Hirohashi Yoshihiko、Torigoe Toshihiko、Kojima Takashi、Osanai Makoto、Takano Kenichi、Miyazaki Akihiro、Suzuki Hiromu
    • Journal Title

      Cancers

      Volume: 15 Issue: 17 Pages: 4303-4303

    • DOI

      10.3390/cancers15174303

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K17188, KAKENHI-PROJECT-21K07985, KAKENHI-PROJECT-22K09687, KAKENHI-PROJECT-23K06445, KAKENHI-PROJECT-21K16846, KAKENHI-PROJECT-23K24186
  • [Journal Article] Regulation of claudin-4 via p63 in human epithelial cells.2017

    • Author(s)
      Kojima T, Kohno T, Kubo T, Kaneko Y, Kakuki T, Kakiuchi A, Kurose M, Takano KI, Ogasawara N, Obata K, Nomura K, Miyata R, Konno T, Ichimiya S, Himi T.
    • Journal Title

      Ann N Y Acad Sci.

      Volume: 1405 Issue: 1 Pages: 25-31

    • DOI

      10.1111/nyas.13456

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26293370, KAKENHI-PROJECT-15K08350, KAKENHI-PROJECT-15K10817
  • [Journal Article] The behavior and role of lipolysis-stimulated lipoprotein receptor, a component of tricellular tight junctions, in head and neck squamous cell carcinomas.2016

    • Author(s)
      Takano K, Kakuki T, Obata K, Nomura K, Miyata R, Kondo A, Kurose M, Kakiuch A, Kaneko Y, Kohno T, Himi T, Kojima T.
    • Journal Title

      Anticancer Research

      Volume: 36 Pages: 5895-5904

    • Data Source
      KAKENHI-PROJECT-15K10817
  • [Journal Article] Dysregulation of junctional adhesion molecule-A via p63/GATA-3 in head and neck squamous cell carcinoma.2016

    • Author(s)
      Kakuki T, Kurose M, TakanoK, Kondoh A, Obata K, Nomura K, Miyata R, Kaneko Y, Konno T, Takahashi S, Hatakeyama T, Kohno T, Himi T, Kojima
    • Journal Title

      Oncotarget

      Volume: 7 Pages: 33887-33900

    • Data Source
      KAKENHI-PROJECT-15K10817
  • [Journal Article] Dysregulation of junctional adhesion molecule-A via p63/GATA-3 in head and neck squamous cell carcinoma.2016

    • Author(s)
      Kakuki T, Kurose M, TakanoK, Kondoh A, Obata K, Nomura K, Miyata R, Kaneko Y, Konno T, Takahashi S, Hatakeyama T, Kohno T, Himi T, Kojima T.
    • Journal Title

      Oncotarget

      Volume: . Issue: 23 Pages: 1-14

    • DOI

      10.18632/oncotarget.8432

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10817, KAKENHI-PROJECT-26462613
  • [Journal Article] Junctional Adhesion Molecule-A in Head and Neck Squamous Cell Carcinoma.2016

    • Author(s)
      Kurose M, Kakuki T, Takano K, Kondo A, Obata K, Nomura K, Miyata R, Kaneko Y, Konno T, Kohno T, Kojima T, Himi T.
    • Journal Title

      Adv. Otorhinolaryngol

      Volume: 77 Pages: 92-97

    • Data Source
      KAKENHI-PROJECT-15K10817
  • [Journal Article] 当科における上咽頭癌症例の検討2013

    • Author(s)
      黒瀬誠, 氷見徹夫
    • Journal Title

      耳展

      Volume: 56補(2) Pages: 172-173

    • NAID

      130004911906

    • Data Source
      KAKENHI-PROJECT-24791794
  • [Journal Article] 当科における上顎扁平上皮癌症例の検討2013

    • Author(s)
      黒瀬誠, 氷見徹夫
    • Journal Title

      耳展

      Volume: 56補(2) Pages: 132-133

    • Data Source
      KAKENHI-PROJECT-24791794
  • [Journal Article] 当科における上咽頭癌症例の検討.2013

    • Author(s)
      黒瀬誠
    • Journal Title

      耳展

      Volume: 56補(2) Pages: 172-173

    • NAID

      130004911906

    • Data Source
      KAKENHI-PROJECT-24791794
  • [Journal Article] Regulation of tight junctions in upper airway epithelium2013

    • Author(s)
      Kojima T, Takano K, Himi T(全19名1, 3, 18番)
    • Journal Title

      Biomed Res Int

      Volume: 2013 Pages: 947072-947072

    • DOI

      10.1155/2013/947072

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390398, KAKENHI-PROJECT-23590404, KAKENHI-PROJECT-23791916, KAKENHI-PROJECT-24659750, KAKENHI-PROJECT-24791794, KAKENHI-PROJECT-25861573, KAKENHI-PROJECT-25861575
  • [Journal Article] 当科における上顎扁平上皮癌症例の検討2013

    • Author(s)
      黒瀬誠
    • Journal Title

      耳展

      Volume: 56補(2) Pages: 132-133

    • Data Source
      KAKENHI-PROJECT-24791794
  • [Journal Article] Mucosal immune barrier and antigen-presenting system in human nasal epithelial cells2011

    • Author(s)
      Himi T, Takano K, Ogasawara N, Go M, Kurose M, Koizumi J, Kamekura R, Kondo A, Ohkuni T, Masaki T, Kojima T, Sawada N, Tsutsumi H
    • Journal Title

      Adv Otorhinolaryngol

      Volume: 72 Pages: 28-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791615
  • [Journal Article] Epithelial barrier and antigen uptake in lymphoepithelium of human adenoids2011

    • Author(s)
      Ogasawara N, Kojima T, Takano K, Kamekura R, Ohkuni T, Koizumi J, Masaki T, Fuchimoto J, Obata K, Kurose M, Shintani T, Sawada N, Himi T
    • Journal Title

      Acta Otolaryngol

      Volume: 131(2) Pages: 116-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791615
  • [Presentation] Lipolysis-stimulated lipoprotein receptor (LSH) antibody or TNF a with HDAC inhibitors promotes apoptosis in human salivary duct carcinoma2023

    • Author(s)
      Kurose M,
    • Organizer
      The 7th world congress of the international federation oh head and neck oncologic societies (IFHNOS)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K09687
  • [Presentation] The behavior and role of tricellular tight junction protein lipolysis-stimulated lipoprotein receptor in head and neck squamous cell carcinomas2017

    • Author(s)
      Makoto Kurose, Akito Kakiuchi, Kenichi Takano, Atsushi Kondo, Takuya Kakuki, Kazufumi Obata, Kazuaki Nomura, Ryo Miyata, Yakuto Kaneko, Tetsuo Himi and Takashi Kojima
    • Organizer
      第5回アジア頭頚部癌学会
    • Place of Presentation
      インドネシア、バリ
    • Year and Date
      2017-03-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10817
  • [Presentation] Effects of histone deacetylase (HDAC) inhibitors on malignancy via p63/JAM-A in head and neck cancer.2017

    • Author(s)
      Akito Kakiuchi, Takuya Kakuki, Makoto Kurose, Kenichi Takano, Atsushi Kondo, Kazufumi Obata, Kazuaki Nomura, Ryo Miyata, Yakuto Kaneko, Tetsuo Himi and Takashi Kojima.
    • Organizer
      5th Congress of Asian Society for Head and Neck Oncology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10817
  • [Presentation] 頭頸部扁平上皮癌におけるヒストン脱アセチル化酵素(HDAC)阻害剤のp63依存性タイト結合分子を介した抗腫瘍効果2017

    • Author(s)
      垣内晃人、角木拓也、黒瀬誠、高野賢一、近藤敦、小幡和史、野村一顕、宮田亮、金子躍人、幸野貴之、氷見徹夫、小島隆
    • Organizer
      第68回日本細胞生物学会
    • Data Source
      KAKENHI-PROJECT-15K10817
  • [Presentation] Effects of histone deacetylase inhibitors on malignancy via p63/JAM-A in head and neck cancer2017

    • Author(s)
      Akito Kakiuchi, Takuya Kakuki, Makoto Kurose, Kenichi Takano, Atsushi Kondo, Kazufumi Obata, Kazuaki Nomura, Ryo Miyata, Yakuto Kaneko, Tetsuo Himi and Takashi Kojima
    • Organizer
      第5回アジア頭頚部癌学会
    • Place of Presentation
      インドネシア、バリ
    • Year and Date
      2017-03-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10817
  • [Presentation] ヒストン脱アセチル化酵素(HDAC)阻害による頭頸部扁平上皮癌タイト結合分子の変化と抗腫瘍効果2017

    • Author(s)
      垣内晃人、角木拓也、黒瀬誠、高野賢一、近藤敦、小幡和史、野村一顕、宮田遼、金子躍人、氷見徹夫、小島隆
    • Organizer
      2017年生命科学系学会合同年次大会
    • Data Source
      KAKENHI-PROJECT-15K10817
  • [Presentation] The behavior and role of tricellular tight junction protein lipolysis-stimulated lipoprotein receptor in head and neck squamous cell carcinomas.2017

    • Author(s)
      Makoto Kurose, Akito Kakiuchi, Kenichi Takano, Atsushi Kondo, Takuya Kakuki, Kazufumi Obata, Kazuaki Nomura, Ryo Miyata, Yakuto Kaneko, Tetsuo Himi, Takashi Kojima.
    • Organizer
      5th Congress of Asian Society for Head and Neck Oncology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10817
  • [Presentation] The Serum Solubilization JAM-A Level of the Head and Neck Squamous Cell Carcinoma Patient Rises.2015

    • Author(s)
      Makoto Kurose, et al.
    • Organizer
      第39回日本頭頸部がん学会総会, 第4回アジア頭頸部癌学会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Year and Date
      2015-06-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10817
  • [Presentation] 頭頸部扁平上皮癌におけるp63/GATA-3経路を介したタイト結合分子JAM-Aの発現調節機構2015

    • Author(s)
      角木拓也、黒瀬誠、高野賢一、近藤敦、小幡和史、野村一顕、宮田遼、金野匠、高橋俊太、畠山翔翼、幸野貴幸、氷見徹夫、小島隆
    • Organizer
      第67回日本細胞生物学会
    • Place of Presentation
      タワーホール船橋(東京都江戸川区)
    • Year and Date
      2015-06-30
    • Data Source
      KAKENHI-PROJECT-15K10817
  • [Presentation] 重症心身障碍児に対する喉頭気管分離術の検討、術式の工夫2014

    • Author(s)
      黒瀬誠
    • Organizer
      喉頭科学会総会
    • Place of Presentation
      那覇
    • Data Source
      KAKENHI-PROJECT-24791794
  • [Presentation] 小児気道確保手術後の気管腕頭動脈瘻への対応2014

    • Author(s)
      黒瀬誠
    • Organizer
      日本頭頚部外科学会総会
    • Place of Presentation
      高松
    • Data Source
      KAKENHI-PROJECT-24791794
  • [Presentation] Negative regulator S100A7 in tumor progression of head and neck squamous carcinoma2013

    • Author(s)
      Nomura K, Kurose M
    • Organizer
      Third Congress of Asian Society of Head and Neck Oncology
    • Place of Presentation
      フィリピン
    • Data Source
      KAKENHI-PROJECT-24791794
  • [Presentation] 頭頸部扁平上皮癌浸潤・転移におけるS100A7(psoriasin) , タイト結合分子JAM-A の意義2013

    • Author(s)
      黒瀬誠, 近藤敦, 氷見徹夫
    • Organizer
      頭頸部癌学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24791794
  • [Presentation] A novel role of tight junction protein JAM-A in invasion and metastasis of head and neck squamous cell carcinoma2013

    • Author(s)
      Obata K, Kurose M
    • Organizer
      Third Congress of Asian Society of Head and Neck Oncology
    • Place of Presentation
      フィリピン
    • Data Source
      KAKENHI-PROJECT-24791794
  • [Presentation] 頭頸部扁平上皮癌におけるタイト結合分子・転写因子の発現2013

    • Author(s)
      黒瀬誠, 近藤敦, 氷見徹夫
    • Organizer
      頭頸部外科学会総会
    • Place of Presentation
      鹿児島
    • Data Source
      KAKENHI-PROJECT-24791794
  • [Presentation] 頭頸部扁平上皮癌浸潤・転移におけるS100A7(psoriasin)、タイト結合分子JAM-Aの意義.2013

    • Author(s)
      黒瀬誠
    • Organizer
      頭頸部癌学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24791794
  • 1.  Takano Kenichi (70404689)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 13 results
  • 2.  Hatakenaka Masmaitsu (40253413)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  Yamamoto Keisuke (50738515)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  HIMI Tetsuo (90181114)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 5.  YOKOTA Shin-ichi (10325863)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  KAMEKURA Ryuta (70404697)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  OHKUNI Tsuyoshi (40464490)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  OGASAWARA Noriko (00438061)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  YAMAMOTO Soh (10588479)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  玉川 光春 (80217174)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  河合 有里子 (70404712)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  荒谷 和紀 (00404715)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  中田 健生 (50457719)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  中村 和正 (20284507)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  吉浦 敬 (40322747)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  山 直也 (20404709)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  小幡 和史 (00548703)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  山本 英一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  小島 隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  畠中 柚衣
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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