TAKAHASHI Noriko 高橋典子

… Alternative Names

高橋典子タカハシノリコ

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Researcher Number	60405777
Other IDs
Affiliation (based on the past Project Information) *help	2011 – 2015: 岩手医科大学, 歯学部, 研究員 2010: 岩手医科大学, 歯学部, 助教 2007: Iwate Medical University, 歯学部, 助教 2006: 岩手医科大学, 歯学部, 助手
Review Section/Research Field	Principal Investigator Periodontology / Dental engineering/Regenerative dentistry / Functional basic dentistry
Keywords	Principal Investigator 歯周組織再生 / 分化 / 破骨細胞 / SCRG1 / 間葉系幹細胞 / 炎症性骨吸収 / 炎症性サイトカイン / 炎症抑制 / 再生歯学 / 口腔腫瘍細胞 … More / シグナル伝達 / ゲルダナマイシン / アポトーシス / Fas / HSP90 Less

Elucidating the molecular mechanism of a peptide, SCRG1, derived from mesenchymal stem cells to suppress the osteoclast differentiation.Principal Investigator
- Principal Investigator
  
  Takahashi Noriko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Iwate Medical University
Research for the regeneration of periodontal tissue using periodontal ligament-derived hemangioblasts-like cellsPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Noriko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Iwate Medical University
口腔由来癌細胞でのFas誘導アポトーシス経路におけるHSP90の作用様式の検索Principal Investigator
- Principal Investigator
  
  高橋典子
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Iwate Medical University

All 2014 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] Novel SCRG1/BST1 axis regulates self-renewal, migration, and osteogenic differentiation potential in mesenchymal stem cells.2014
- Author(s)
  Aomatsu, E., Takahashi, N., Sawada, S., Okubo, N., Hasegawa, T., Taira, M., Miura, H., Ishisaki, A., and Chosa, N.
- Journal Title
  
  Sci. Rep.
  
  Volume: 4 Issue: 1 Pages: 3652-3652
- DOI
  10.1038/srep03652
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23592896, KAKENHI-PROJECT-24792149, KAKENHI-PROJECT-25463053, KAKENHI-PROJECT-25463182, KAKENHI-PROJECT-25463224, KAKENHI-PROJECT-25893221, KAKENHI-PROJECT-26893249
[Journal Article] The homeobox gene DLX4 promotes generation of human induced pluripotent stem cells2014
- Author(s)
  Naritaka Tamaoki, Kazutoshi Takahashi, Hitomi Aoki, Kazuki Iida, Tomoko Kawaguchi, Daijirou Hatakeyama, Masatoshi Inden, Naoyuki Chosa, Akira Ishisaki, Takahiro Kunisada, Toshiyuki Shibata, Naoki Goshima, Shinya Yamanaka, and Ken-ichi Tezuka
- Journal Title
  
  Scientific Reports
  
  Volume: なし Issue: 1 Pages: 7283-7283
- DOI
  10.1038/srep07283
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24792197, KAKENHI-PROJECT-25463053, KAKENHI-PROJECT-25463224, KAKENHI-PROJECT-26293426, KAKENHI-PROJECT-26463000, KAKENHI-PROJECT-26463001, KAKENHI-PROJECT-26670862
[Journal Article] 間葉系幹細胞のstemnessを維持するシグナル伝達経路2014
- Author(s)
  帖佐直幸, 菊池-青松恵美子, 西平宗功, 横田潤, 高橋典子, 近藤尚知, 杉山芳樹, 三浦廣行, 石崎明.
- Journal Title
  
  岩手医科大学歯学雑誌
  
  Volume: 39 Pages: 56-65
- NAID
  110009857549
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25463224
[Journal Article] PDGF-induced PI3K-mediated signal enhances TGF-βinduced osteogenic differentiation of human mesenchymal stem cells in the TGF-β-activated MEK-dependent manner2014
- Author(s)
  Jun Yokota, Naoyuki Chosa, Shunsuke Sawada, Naoto Okubo, Noriko Takahashi, Tomokazu Hasegawa, Hisatomo Kondo, Akira Ishisaki
- Journal Title
  
  International Journal of Molecular Medicine
  
  Volume: 33 Issue: 3 Pages: 534-542
- DOI
  10.3892/ijmm.2013.1606
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23592864, KAKENHI-PROJECT-23592896, KAKENHI-PROJECT-24792149, KAKENHI-PROJECT-25463053, KAKENHI-PROJECT-25463224, KAKENHI-PROJECT-25893221
[Journal Article] Transforming growth factor-β1 induces epithelialmesenchymal transition and integrin α3β1-mediated cell migration of HSC-4 human squamous cell carcinoma cells through Slug2013
- Author(s)
  Saito D, Kyakumoto S, Chosa N, Ibi M, Takahashi,N, Okubo N, Sawada S, Ishisaki A, & Kamo M
- Journal Title
  
  J. Biochem
  
  Volume: 153 Issue: 3 Pages: 303-315
- DOI
  10.1093/jb/mvs144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592076, KAKENHI-PROJECT-22791936, KAKENHI-PROJECT-23592896, KAKENHI-PROJECT-24792149
[Journal Article] Fibroblast growth factor-1-induced ERK1/2 signaling reciprocally regulates proliferation and smooth muscle cell differentiation of ligament-derived endothelial progenitor cell-like cells2012
- Author(s)
  Takahahi M, Okubo N, Chosa N, Takahashi N, Miho I, Kamo M, Mizuki H, Ishisaki A, & Kyakumoto S
- Journal Title
  
  Int. J. Mol.Med.
  
  Volume: 29 Pages: 357-364
- DOI
  10.3892/ijmm.2011.847
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592076, KAKENHI-PROJECT-22791935, KAKENHI-PROJECT-22791936, KAKENHI-PROJECT-23592896, KAKENHI-PROJECT-24792149
[Journal Article] High-cell density-induced VCAM1 expression inhibits the migratory ability of mesenchymal stem cells2011
- Author(s)
  Nishihira S, Okubo N, et al.
- Journal Title
  
  Cell Biology International
  
  Volume: 35巻 Issue: 5 Pages: 475-481
- DOI
  10.1042/cbi20100372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791935, KAKENHI-PROJECT-22791936, KAKENHI-PROJECT-23592896
[Journal Article] Dental pulp cells derived from permanent teeth express higher levels of R-cadher in than do deciduous teeth : Implications of the correlation between R-cadherin expression and restriction of multipotency in mesenchymal stem cells2011
- Author(s)
  Takahashi N
- Journal Title
  
  Archives of Oral Biology
  
  Volume: 57 Issue: 1 Pages: 44-51
- DOI
  10.1016/j.archoralbio.2011.07.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592076, KAKENHI-PROJECT-22592296, KAKENHI-PROJECT-22791935, KAKENHI-PROJECT-22791936, KAKENHI-PROJECT-23592896, KAKENHI-PROJECT-24792149
[Presentation] 複数サイトカインによる同時刺激は間葉系幹細胞の骨分化誘導性を促進する2013
- Author(s)
  横田潤　帖佐直幸　高橋典子　衣斐美歩　客本斉子　加茂政晴　長谷川智一　近藤尚知　石崎明
- Organizer
  第55回歯科基礎医学会学術大会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-25463224
[Presentation] サイトカイン様ペプチドSCRG１は間葉系幹細胞の骨ならびに脂肪分化を抑制する2013
- Author(s)
  青松恵美子　帖佐直幸　大久保直登　衣斐美歩　高橋典子　客本斉子　加茂政晴　長谷川智一　佐藤和朗　三浦廣行　石崎明
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25463224
[Presentation] TGF-βを介したヒト口腔扁平上皮癌細胞 HSC-4 における上皮間葉転換について2012
- Author(s)
  斎藤大嗣帖佐直幸客本斉子高橋典子大久保直登衣斐美歩水城春美石崎明加茂政晴
- Organizer
  日本分子生物学会第12回春季シンポジウム
- Place of Presentation
  山梨
- Data Source
  KAKENHI-PROJECT-22791936
[Presentation] TGF-βにより誘導された上皮間葉転換に伴うヒト口腔扁平上皮癌細胞の細胞運動の解析2012
- Author(s)
  齋藤大嗣帖佐直幸客本斉子高橋典子大久保直登衣斐美歩石崎明加茂政晴
- Organizer
  第54回歯科基礎医学会学術大会・総会
- Place of Presentation
  福島
- Data Source
  KAKENHI-PROJECT-22791936
[Presentation] TGF-βと IGF-1、PDGFまたは VEGF の同時刺激は間葉系幹細胞の骨分化を促進する2012
- Author(s)
  横田潤帖佐直幸大久保直登衣斐美歩高橋典子客本斉子加茂政晴近藤尚知石崎明
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22791936
[Presentation] 間葉系幹細胞由来サイトカイン様ペプチド SCRG1は破骨細胞分化を抑制する2012
- Author(s)
  青松恵美子帖佐直幸大久保直登衣斐美歩高橋典子客本斉子加茂政晴佐藤和朗三浦廣行石崎明
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22791936
[Presentation] ヒト口腔扁平上皮癌細胞における TGF-β1 による上皮間葉転換に伴う細胞遊走能の解析2012
- Author(s)
  齋藤大嗣帖佐直幸客本斉子高橋典子大久保直登衣斐美歩水城春美石崎明加茂政晴
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22791936
[Presentation] TGF-βによる歯周靭帯由来血管内皮前駆細胞様細胞の増殖抑制と平滑筋細胞様分化のシグナル解析2012
- Author(s)
  客本斉子吉田茉莉子大久保直登帖佐直幸長谷川智一高橋典子衣斐美歩加茂政晴石崎明
- Organizer
  第54回歯科基礎医学会学術大会・総会
- Place of Presentation
  福島
- Data Source
  KAKENHI-PROJECT-22791936
[Presentation] 歯周靭帯由来細胞の血管構成細胞分化における TGF-βの関与について2011
- Author(s)
  吉田茉莉子大久保直登帖佐直幸客本斉子高橋典子衣斐美歩長谷川智一加茂政晴石崎明
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22791936
[Presentation] TGF- β-induced smooth muscle cell differentiation of ligament-derived endothelial progenitor-like cells2011
- Author(s)
  Naoto Okubo, Mariko Yoshida, Naoyuki Chosa, Seiko Kyakumoto, Noriko Takahashi, Miho Ibi, Tomokazu Hasegawa, Masaharu Kamo, Akira Ishisaki
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22791936
[Presentation] 歯周靭帯由来細胞の血管構成細胞分化における TGF-βの関与について2011
- Author(s)
  吉田茉莉子大久保直登帖佐直幸客本斉子高橋典子衣斐美歩長谷川智一加茂政晴石崎明
- Organizer
  第53回歯科基礎医学会学術大会・総会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-22791936
[Presentation] 歯周靭帯由来線維細胞の増殖と平滑筋分化はFGFで誘導されるERKシグナルにより制御される2011
- Author(s)
  高橋美香子
- Organizer
  第53回歯科基礎医学会学術大会・総会
- Place of Presentation
  岐阜
- Year and Date
  2011-10-01
- Data Source
  KAKENHI-PROJECT-22791936
[Presentation] 歯周靭帯由来線維細胞の増殖と平滑筋分化は FGF で誘導される ERK シグナルにより制御される2011
- Author(s)
  高橋美香子大久保直登帖佐直幸高橋典子長谷川智一客本斉子加茂政晴水城春美石崎明
- Organizer
  第53回歯科基礎医学会学術大会・総会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-22791936
[Presentation] 繊維芽細胞増殖因子で誘導される ERK1/2 シグナルは靭帯由来血管内皮前駆細胞の増殖と平滑筋分化を相反的に制御する2011
- Author(s)
  高橋美香子大久保直登帖佐直幸高橋典子衣斐美歩長谷川智一加茂政晴水城春美石崎明客本斉子
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22791936
[Presentation] ヒト口腔扁平上皮癌細胞における TGF-β による上皮間葉転換について2011
- Author(s)
  齋藤大嗣加茂政晴帖佐直幸客本斉子高橋典子大久保直登衣斐美歩水城春美石崎明
- Organizer
  第48回日本口腔組織培養学会学術大会
- Place of Presentation
  浦安
- Year and Date
  2011-11-19
- Data Source
  KAKENHI-PROJECT-22791936
[Presentation] ヒト口腔扁平上皮癌細胞における TGF-βシグナル伝達を介した細胞運動メカニズムの解析2011
- Author(s)
  齋藤大嗣加茂政晴帖佐直幸客本斉子高橋典子大久保直登衣斐美歩水城春美石崎明
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22791936
[Presentation] PDGF 受容体を介した VCAM1 の発現は間葉系幹細胞の遊走を制御する2010
- Author(s)
  西平宗功大久保直登高橋典子長谷川智一帖佐直幸杉山芳樹石崎明
- Organizer
  第52回歯科基礎医学会学術大会ならびに総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22791936
[Presentation] システインリッチペプチド SCRG1 は間葉系幹細胞の移動能を促進する2010
- Author(s)
  帖佐直幸西平宗功大久保直登高橋典子客本斉子加茂政晴石崎明
- Organizer
  第52回歯科基礎医学会学術大会ならびに総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22791936

1. Chosa Naoyuki (80326694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. Ishisaki Akira (20356439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
3. TAMAOKI Naritaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 加茂政晴

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 大久保直登

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 近藤尚知

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKAHASHI Noriko 高橋 典子

高橋 典子 タカハシ ノリコ

Research Projects

Research Products

Co-Researchers

Elucidating the molecular mechanism of a peptide, SCRG1, derived from mesenchymal stem cells to suppress the osteoclast differentiation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research for the regeneration of periodontal tissue using periodontal ligament-derived hemangioblasts-like cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

口腔由来癌細胞でのFas誘導アポトーシス経路におけるHSP90の作用様式の検索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Novel SCRG1/BST1 axis regulates self-renewal, migration, and osteogenic differentiation potential in mesenchymal stem cells.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The homeobox gene DLX4 promotes generation of human induced pluripotent stem cells2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 間葉系幹細胞のstemnessを維持するシグナル伝達経路2014

Author(s)

Journal Title

NAID

Data Source

[Journal Article] PDGF-induced PI3K-mediated signal enhances TGF-βinduced osteogenic differentiation of human mesenchymal stem cells in the TGF-β-activated MEK-dependent manner2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transforming growth factor-β1 induces epithelialmesenchymal transition and integrin α3β1-mediated cell migration of HSC-4 human squamous cell carcinoma cells through Slug2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fibroblast growth factor-1-induced ERK1/2 signaling reciprocally regulates proliferation and smooth muscle cell differentiation of ligament-derived endothelial progenitor cell-like cells2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High-cell density-induced VCAM1 expression inhibits the migratory ability of mesenchymal stem cells2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dental pulp cells derived from permanent teeth express higher levels of R-cadher in than do deciduous teeth : Implications of the correlation between R-cadherin expression and restriction of multipotency in mesenchymal stem cells2011

Author(s)

Journal Title

DOI

Data Source

[Presentation] 複数サイトカインによる同時刺激は間葉系幹細胞の骨分化誘導性を促進する2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] サイトカイン様ペプチドSCRG１は間葉系幹細胞の骨ならびに脂肪分化を抑制する2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] TGF-βを介したヒト口腔扁平上皮癌細胞 HSC-4 における上皮間葉転換について2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] TGF-βにより誘導された上皮間葉転換に伴うヒト口腔扁平上皮癌細胞の細胞運動の解析2012

Author(s)

TAKAHASHI Noriko 高橋典子

高橋典子タカハシノリコ