TAKEDA Kumiko 武田久美子

Researcher Number	60414695
Other IDs
Affiliation (Current)	2025: 国立研究開発法人農業・食品産業技術総合研究機構, 畜産研究部門, 上級研究員
Affiliation (based on the past Project Information) *help	2023: 国立研究開発法人農業・食品産業技術総合研究機構, 畜産研究部門乳牛精密管理研究領域, 上級研究員 2018 – 2023: 国立研究開発法人農業・食品産業技術総合研究機構, 畜産研究部門, 上級研究員 2020: 国立研究開発法人農業・食品産業技術総合研究機構, 畜産研究部門乳牛精密管理研究領域, 上級研究員 2017 – 2019: 国立研究開発法人農業・食品産業技術総合研究機構, 畜産研究部門家畜育種繁殖研究領域, 上級研究員 2016: 国立研究開発法人農業・食品産業技術総合研究機構, 畜産研究部門家畜育種繁殖研究領域, 上級研究員
Review Section/Research Field	Principal Investigator Basic Section 42010:Animal production science-related / Animal production science Except Principal Investigator Medium-sized Section 39:Agricultural and environmental biology and related fields / Basic Section 42030:Animal life science-related
Keywords	Principal Investigator 精子 / ウシ / メチル化 / 受胎性 / DNAメチル化 / 受精 / クロマチン / チオール基 / DNA正常性 / 牛 … More / 全ゲノムバイサルファイトシークエンス / 受胎率 / 人工授精 / 雄 / 受胎性評価 / 繁殖 / 畜産学 / マイクロアレイ / 月齢変化 / 体外受精 … More Except Principal Investigator 哺乳動物細胞 / 精子 / 初期胚発生 / 還元型グルタチオン / ウシ / 乾眠 / 哺乳動物細胞の遺伝資源保存 / 初期胚のエピゲノム / 乾燥耐性 / 哺乳類の初期発生機構 / 発生機構 / 遺伝子資源保存 / フリーズドライ / 凍結乾燥保存 / 哺乳動物 / 遺伝資源保存 / 生殖工学 / 体細胞 / 哺乳動物遺伝資源 / 凍結乾燥 Less

Fundamental Studies on anhydrobiosis of mammalian cells
- Principal Investigator
  
  松川和嗣
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 39:Agricultural and environmental biology and related fields
- Research Institution
  Kochi University
チオール基反応性物質のウシ精子クロマチンへの影響および精子評価への利用Principal Investigator
- Principal Investigator
  
  武田久美子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  National Agriculture and Food Research Organization
外因性GSHがウシ精子に与える初期胚発生へのアドバンテージの解明
- Principal Investigator
  
  緒方和子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  National Agriculture and Food Research Organization
Evaluation of bull fertility for bovine spermatozoa and embryos using differentially methylated CpG sites as biomarkersPrincipal Investigator
- Principal Investigator
  
  Takeda Kumiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  National Agriculture and Food Research Organization
Preservation of mammalian genetic resources and study for the developmental mechanism using freeze-dried cells
- Principal Investigator
  
  Matsukawa Kazutsugu
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 39:Agricultural and environmental biology and related fields
- Research Institution
  Kochi University
Elucidation of DNA methylation status of bovine spermatozoa related to embryo development after in vitro fertilization and conception after artificial inseminationPrincipal Investigator
- Principal Investigator
  
  TAKEDA Kumiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Animal production science
- Research Institution
  National Agriculture and Food Research Organization

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Differentially methylated CpG sites related to fertility in Japanese Black bull spermatozoa: epigenetic biomarker candidates to predict sire conception rate2021
- Author(s)
  TAKEDA Kumiko、KOBAYASHI Eiji、OGATA Kazuko、IMAI Akira、SATO Shinya、ADACHI Hiromichi、HOSHINO Yoichiro、NISHINO Kagetomo、INOUE Masahiro、KANEDA Masahiro、WATANABE Shinya
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 67 Issue: 2 Pages: 99-107
- DOI
  10.1262/jrd.2020-137
- NAID
  130008028375
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06368, KAKENHI-PROJECT-19K06362
[Journal Article] Age-related changes in DNA methylation levels at CpG sites in bull spermatozoa and <i>in vitro</i> fertilization-derived blastocyst-stage embryos revealed by combined bisulfite restriction analysis2019
- Author(s)
  ①Kumiko Takeda, Eiji Kobayashi, Kagetomo Nishino, Akira Imai, Hiromichi Adachi, Yoichiro Hoshino, Satoshi Akagi, Masahiro Kaneda, Shinya Watanabe
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 65 Issue: 4 Pages: 305-312
- DOI
  10.1262/jrd.2018-146
- NAID
  130007689001
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07999, KAKENHI-PROJECT-19K06362, KAKENHI-PROJECT-19K06368
[Journal Article] Differentially methylated CpG sites in bull spermatozoa revealed by human DNA methylation arrays and bisulfite analysis2017
- Author(s)
  Kumiko Takeda, Eiji Kobayashi, Satoshi Akagi, kagetomo Nishino, Masahiro Kaneda, Shinya Watanabe
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 63 Issue: 3 Pages: 279-287
- DOI
  10.1262/jrd.2016-160
- NAID
  130007314612
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07999
[Presentation] The effect of thiol substances after freeze-thawing of bull semen on the frequency of spermatozoa with nuclear DNA damage.2024
- Author(s)
  武田久美子・緒方和子・横川広明・石川恭子
- Organizer
  The 20th Asian-Australasian Association of Animal Production Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05514
[Presentation] Effects of reduced glutathione supplementation to semen freezing extender on glutathione and thiol content in frozen-thawed bull spermatozoa2024
- Author(s)
  Kazuko Ogata, Hiroaki Yokokawa, Kyoko Ishikawa, Kumiko Takeda
- Organizer
  Joint AAAP & AAAS Animal Production Congress 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05598
[Presentation] ウシ精子の生存性および先体正常性の同時評価のためのカルセインブルーAM染色の有効性の検討2023
- Author(s)
  緒方和子、横川広明、石川恭子、武田久美子
- Organizer
  第7回日本胚移植技術研究会大会
- Data Source
  KAKENHI-PROJECT-23K05598
[Presentation] フリーズドライ技術を用いたウシ精子の保存が胚発生に与える影響2022
- Author(s)
  下島小麦，亀田崇史，水野つかさ，武田久美子，緒方和子，郡七海，枝重圭祐，松川和嗣
- Organizer
  第115回日本繁殖生物学会
- Data Source
  KAKENHI-PROJECT-18H03953
[Presentation] 精子核DNAメチル化可変領域を利用した黒毛和種凍結精液の人工授精後の受胎性予測の試み2021
- Author(s)
  武田久美子、緒方和子、今井昭、佐藤伸哉、井上真寛、木村和輝、熊崎啓将、金田正弘、小林栄治
- Organizer
  第114回日本繁殖生物学会大会
- Data Source
  KAKENHI-PROJECT-19K06362
[Presentation] ヒトメチル化アレイを用いたウシメチル化可変部位の網羅的解析2021
- Author(s)
  小林栄治、緒方和子、武田久美子
- Organizer
  第22回動物遺伝育種学会
- Data Source
  KAKENHI-PROJECT-19K06362
[Presentation] 黒毛和種雄牛の人工授精後の受胎性指標とする精子核DNAメチル化可変部位追加による評価精度の向上2020
- Author(s)
  武田久美子、小林栄治、緒方和子、今井昭、佐藤伸哉、木村和輝、安達広通、井上真寛、金田正弘、渡邊伸也
- Organizer
  第113回日本繁殖生物学会大会
- Data Source
  KAKENHI-PROJECT-19K06362
[Presentation] 体外受精胚発生率に関連しうる牛精子核DNAのメチル化可変部位の探索2019
- Author(s)
  武田久美子,小林栄治,今井昭,佐藤伸哉,西野景知,安達広通,岩尾健,赤木悟史,金田正弘,渡邊伸也
- Organizer
  日本畜産学会第125回大会
- Data Source
  KAKENHI-PROJECT-16K07999
[Presentation] 受胎性と関連しうる精子核DNAメチル化可変部位の体外受精胚におけるメチル化状態2019
- Author(s)
  武田久美子、小林栄治、西野景知、星野洋一郎、安達広通、今井昭、岩尾健、緒方和子、金田正弘、渡邊伸也
- Organizer
  第112回日本繁殖生物学会大会
- Data Source
  KAKENHI-PROJECT-19K06362
[Presentation] 液体窒素を使用しない凍結乾燥精子を用いたウシ体外受精胚作出の試み2019
- Author(s)
  松川和嗣、横山輝智香、及川俊徳、緒方和子、武田久美子、枝重圭祐
- Organizer
  日本畜産学会
- Data Source
  KAKENHI-PROJECT-18H03953
[Presentation] 牛精子核DNAのメチル化可変部位と凍結精液受胎率との関連性の検討2018
- Author(s)
  武田久美子、小林栄治、星野洋一郎、安達広通、今井昭、西野景知、岩尾健、金田正弘、渡邊伸也
- Organizer
  日本畜産学会第124回大会
- Data Source
  KAKENHI-PROJECT-16K07999
[Presentation] 哺乳動物細胞におけるフリーズドライ保存の可能性と課題2018
- Author(s)
  松川　和嗣, 本郷新, 井上　陽香, 横山輝智香, 森澤　啓子, 樋口　琢磨, 坂本　修士, 及川　俊徳, 斎藤　公治, 赤木　悟史, 武田　久美子, 黄川田　隆洋, 市川　明彦, 枝重　圭祐
- Organizer
  Cryopreservation Conference 2018
- Data Source
  KAKENHI-PROJECT-18H03953
[Presentation] Age-dependent changes of DNA methylation levels in bull spermatozoa2018
- Author(s)
  Kumiko Takeda
- Organizer
  INRA-NARO Joint Symposium: Cutting-edge Research on Animal Breeding and Reproduction
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07999
[Presentation] 体外受精後の胚における牛精子核DNAメチル化可変部位のメチル化状態2018
- Author(s)
  武田久美子, 小林栄治, 星野洋一郎, 安達広通, 今井昭, 西野景知, 岩尾健, 金田正弘, 渡邊伸也
- Organizer
  INRA-NARO Joint Symposium: Cutting-edge Research on Animal Breeding and Reproduction
- Data Source
  KAKENHI-PROJECT-16K07999
[Presentation] ウシ除核卵母細胞を用いた雄性発生胚の効率的作出2018
- Author(s)
  本郷新、樋口琢磨、坂本修士、赤木悟史、武田久美子、及川俊徳、枝重圭祐、松川和嗣
- Organizer
  第111回日本繁殖生物学会
- Data Source
  KAKENHI-PROJECT-18H03953
[Presentation] Age-related changes in DNA methylation levels of CpG sites in bull spermatozoa and IVF embryos.2017
- Author(s)
  Kumiko Takeda, Eiji Kobayashi, Kagetomo Nishino, Akira Imai, Hiromichi Adachi, Yoichiro Hoshino, Satoshi Akagi, Masahiro Kaneda, Shinya Watanabe
- Organizer
  4th World Congress of Reproductive Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07999
[Presentation] 牛精液凍結時の還元型Lグルタチオンの添加が体外受精胚発生率に与える効果2017
- Author(s)
  武田久美子・小林栄治・赤木悟史・渡邊伸也
- Organizer
  日本畜産学会122回大会
- Place of Presentation
  神戸大学（兵庫県・神戸市）
- Year and Date
  2017-03-27
- Data Source
  KAKENHI-PROJECT-16K07999
[Presentation] 人工授精後の受胎率に関連する牛精子核DNAのメチル化可変部位の検出2017
- Author(s)
  武田久美子、小林栄治、星野洋一郎、安達広通、今井昭、西野景知、岩尾健、金田正弘、渡邊伸也
- Organizer
  日本受精卵移植関連合同研究会
- Data Source
  KAKENHI-PROJECT-16K07999
[Presentation] ヒトメチル化チップを用いたウシCpGサイトの網羅的メチル化解析2017
- Author(s)
  小林栄治・武田久美子
- Organizer
  日本畜産学会122回大会
- Place of Presentation
  神戸大学（兵庫県・神戸市）
- Year and Date
  2017-03-27
- Data Source
  KAKENHI-PROJECT-16K07999
[Presentation] 繁殖供用開始期の雄牛精子核DNAの特定メチル化可変部位におけるメチル化状態の差異2016
- Author(s)
  武田久美子・小林栄治・西野景知・今井昭・金田正弘・渡邊伸也
- Organizer
  日本繁殖生物学会109回大会
- Place of Presentation
  麻布大学（神奈川県・相模原市）
- Year and Date
  2016-09-12
- Data Source
  KAKENHI-PROJECT-16K07999
[Presentation] Differentially methylated CpG sites in bull sperm DNA revealed by human DNA methylation arrays2016
- Author(s)
  Kumiko Takeda, Eiji Kobayashi, Satoshi Akagi, Masahiro Kaneda, Shinya Watanabe
- Organizer
  第１７回アジア・大洋州畜産国際会議(AAAP2016)
- Place of Presentation
  福岡産業大学（福岡県・福岡市）
- Year and Date
  2016-08-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07999

1. 緒方和子 (40761614)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
2. Matsukawa Kazutsugu (00532160)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. 小林栄治 (00186727)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
4. 市川明彦 (20377823)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 枝重圭祐 (30175228)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. 及川俊徳 (70588962)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. 樋口琢磨 (10754567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 黄川田隆洋 (60414900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 赤木悟史 (70414696)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 坂本修士 (80397546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 郡七海 (30966289)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. WATANABE shinya

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
13. HOSHINO yoichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
14. NISHINO kagetomo

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
15. IMAI akira

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
16. ADACHI hiromichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
17. IWAO ken

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
18. KANEDA masahiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results

TAKEDA Kumiko 武田 久美子

Research Projects

Research Products

Co-Researchers

Fundamental Studies on anhydrobiosis of mammalian cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

チオール基反応性物質のウシ精子クロマチンへの影響および精子評価への利用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

外因性GSHがウシ精子に与える初期胚発生へのアドバンテージの解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Evaluation of bull fertility for bovine spermatozoa and embryos using differentially methylated CpG sites as biomarkersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Preservation of mammalian genetic resources and study for the developmental mechanism using freeze-dried cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of DNA methylation status of bovine spermatozoa related to embryo development after in vitro fertilization and conception after artificial inseminationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Differentially methylated CpG sites related to fertility in Japanese Black bull spermatozoa: epigenetic biomarker candidates to predict sire conception rate2021

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Age-related changes in DNA methylation levels at CpG sites in bull spermatozoa and <i>in vitro</i> fertilization-derived blastocyst-stage embryos revealed by combined bisulfite restriction analysis2019

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Differentially methylated CpG sites in bull spermatozoa revealed by human DNA methylation arrays and bisulfite analysis2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Presentation] The effect of thiol substances after freeze-thawing of bull semen on the frequency of spermatozoa with nuclear DNA damage.2024

Author(s)

Organizer

Data Source

[Presentation] Effects of reduced glutathione supplementation to semen freezing extender on glutathione and thiol content in frozen-thawed bull spermatozoa2024

Author(s)

Organizer

Data Source

[Presentation] ウシ精子の生存性および先体正常性の同時評価のための カルセインブルーAM染色の有効性の検討2023

Author(s)

Organizer

Data Source

[Presentation] フリーズドライ技術を用いたウシ精子の保存が胚発生に与える影響2022

Author(s)

Organizer

Data Source

TAKEDA Kumiko 武田久美子

[Presentation] ウシ精子の生存性および先体正常性の同時評価のためのカルセインブルーAM染色の有効性の検討2023