Kochi Yuta 高地雄太

… Alternative Names

KOCHI Yuta 高地雄太

高地雄太コウチユウタ

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Researcher Number	60415156
Other IDs
External Links
Affiliation (Current)	2025: 東京科学大学, 総合研究院, 教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 東京医科歯科大学, 難治疾患研究所, 教授 2015 – 2016: 国立研究開発法人理化学研究所, 統合生命医科学研究センター, 副チームリーダー 2014: 独立行政法人理化学研究所, 統合生命医科学研究センター, 副チームリーダー 2013: 独立行政法人理化学研究所, 統合生命医科学研究センター, 上級研究員 2011 – 2012: 独立行政法人理化学研究所, 自己免疫疾患研究チーム, 上級研究員 2007: The Institute of Physical and Chemical Research, 関節リウマチ関連遺伝子研究チーム, 研究員 2006: 独立行政法人理化学研究所, 関節リウマチ関連遺伝子研究チーム, 研究員
Review Section/Research Field	Principal Investigator 膠原病・アレルギー・感染症内科学 / Basic Section 43050:Genome biology-related / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Basic Section 54020:Connective tissue disease and allergy-related / Collagenous pathology/Allergology Except Principal Investigator Basic Section 56020:Orthopedics-related / Basic Section 56060:Ophthalmology-related / Basic Section 54020:Connective tissue disease and allergy-related
Keywords	Principal Investigator ゲノムワイド関連解析 / 自己免疫疾患 / 関節リウマチ / GWAS / long-read RNA-seq / sQTL / 遺伝子多型 / 選択的スプライシング / ナンセンス変異依存mRNA分解機構 / 自然免疫刺激 … More / レトロエレメント / ロングリードシークエンシング / splicing QTL / ロングリードシークエンス / 次世代シークエンサー / ケースコントロール関連解析 / rare variant / 病態予測 / Th17細胞 / Th1細胞 / Th17 細胞 / Th1 細胞 / 遺伝学 / 疾患感受性遺伝子 / B細胞 / ケース・コントロール関連解析 … More Except Principal Investigator 関節リウマチ / SHS / PRS / ゲノム / 関節破壊 / AI / 人工知能 / 角膜内皮細胞 / フックス角膜内皮ジストロフィ / リピート病 / ゲノム編集 / メトトレキサート / MTX-LPD / 関連遺伝子 / メトトレキサート関連リンパ増殖性疾患 / ゲノムワイド関連解析 / メトトレキサート関連リンパ腫 / 遺伝子 / リンパ腫 Less

Fuchs角膜内皮変性症に対するゲノム医療の開発
- Principal Investigator
  
  宮井尊史
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  The University of Tokyo
Pathophysiological study of NMD-targeted transcripts by trans-omics analysisPrincipal Investigator
- Principal Investigator
  
  高地雄太
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  Tokyo Medical and Dental University
AI読影を活用したGWASに基づく関節リウマチにおける関節破壊予測システムの構築
- Principal Investigator
  
  猪狩勝則
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Tokyo Women's Medical University
Dissecting the role of retroelements and their variations in autoimmune diseasesPrincipal Investigator
- Principal Investigator
  
  Kochi Yuta
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Tokyo Medical and Dental University
A genome-wide association study in Japanese patients with rheumatoid arthritis in order to identify susceptibility loci for Methotrexate-associated lymphoproliferative disorder.
- Principal Investigator
  
  Harigai Masayoshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Tokyo Women's Medical University
Dissecting the mechanism of autoimmune diseases using sQTL in immune cellsPrincipal Investigator
- Principal Investigator
  
  Kochi Yuta
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Tokyo Medical and Dental University
Rare variant analysis of rheumatoid arthritis associated genes.Principal Investigator
- Principal Investigator
  
  Kochi Yuta
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Institute of Physical and Chemical Research
Genetic prediction of Th1 and Th17 cells activity in rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  KOCHI Yuta
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The Institute of Physical and Chemical Research
関節リウマチ感受性遺伝子FCRL3を標的とした創薬のための基盤研究Principal Investigator
- Principal Investigator
  
  高地雄太
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The Institute of Physical and Chemical Research

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All Journal Article Presentation

[Journal Article] Munc13-4 regulates asthma and obesity in mice by controlling functions of CD11c+ antigen-presenting cells.2024
- Author(s)
  Okunishi K, Kochi Y, Zhao M, Wang H, Nakagome K, Izumi T
- Journal Title
  
  Allergy
  
  Volume: Online ahead of print Issue: 7 Pages: 1992-1995
- DOI
  10.1111/all.16087
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08796, KAKENHI-PROJECT-23K23860, KAKENHI-PROJECT-23K27992
[Journal Article] Attenuation of HOIL-1L ligase activity promotes systemic autoimmune disorders by augmenting linear ubiquitin signaling2024
- Author(s)
  Fuseya Yasuhiro、Kadoba Keiichiro、Liu Xiaoxi、Suetsugu Hiroyuki、Iwasaki Takeshi、Ohmura Koichiro、Sumida Takayuki、Kochi Yuta、Morinobu Akio、Terao Chikashi、Iwai Kazuhiro
- Journal Title
  
  JCI Insight
  
  Volume: 9 Issue: 3
- DOI
  10.1172/jci.insight.171108
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07887, KAKENHI-PROJECT-22K15379, KAKENHI-WRAPUP-23H05424, KAKENHI-PROJECT-22H04988, KAKENHI-PROJECT-23K23860
[Journal Article] Uncovering the Localization and Function of a Novel Read-Through Transcript ‘TOMM40-APOE’2023
- Author(s)
  Chang Shichen、Torii Satoru、Inamo Jun、Ishikawa Kinya、Kochi Yuta、Shimizu Shigeomi
- Journal Title
  
  Cells
  
  Volume: 13 Issue: 1 Pages: 69-69
- DOI
  10.3390/cells13010069
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05748, KAKENHI-PROJECT-23K23860
[Journal Article] Utility of tissue-specific gene expression scores for gene prioritization in Mendelian diseases2022
- Author(s)
  Kato Daiki、Mitsuhashi Satomi、Miya Fuyuki、Saitoh Shinji、Okamoto Nobuhiko、Tsunoda Tatsuhiko、Kochi Yuta
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 67 Issue: 12 Pages: 739-742
- DOI
  10.1038/s10038-022-01071-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03646, KAKENHI-PROJECT-21K19501
[Journal Article] Splicing QTL analysis focusing on coding sequences reveals pathogenicity of disease susceptibility loci2022
- Author(s)
  Yamaguchi Kensuke、Ishigaki Kazuyoshi、Suzuki Akari、Tsuchida Yumi、Tsuchiya Haruka、Sumitomo Shuji、Nagafuchi Yasuo、Miya Fuyuki、Tsunoda Tatsuhiko、Hirofumi Shoda、Fujio Keishi、Yamamoto Kazuhiko、Kochi Yuta
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2021.12.30.474578
- Data Source
  KAKENHI-PROJECT-18H02849, KAKENHI-PROJECT-21K19501
[Journal Article] Association of Polygenic Risk Scores With Radiographic Progression in Patients With Rheumatoid Arthritis2022
- Author(s)
  Honda Suguru、Ikari Katsunori、Yano Koichiro、Terao Chikashi、Tanaka Eiichi、Harigai Masayoshi、Kochi Yuta
- Journal Title
  
  Arthritis & Rheumatology
  
  Volume: - Issue: 5 Pages: 791-800
- DOI
  10.1002/art.42051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09583, KAKENHI-PROJECT-20H03722
[Journal Article] Splicing QTL analysis focusing on coding sequences reveals mechanisms for disease susceptibility loci2022
- Author(s)
  Yamaguchi Kensuke、Ishigaki Kazuyoshi、Suzuki Akari、Tsuchida Yumi、Tsuchiya Haruka、Sumitomo Shuji、Nagafuchi Yasuo、Miya Fuyuki、Tsunoda Tatsuhiko、Shoda Hirofumi、Fujio Keishi、Yamamoto Kazuhiko、Kochi Yuta
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 4659-4659
- DOI
  10.1038/s41467-022-32358-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05285, KAKENHI-PROJECT-20K08800, KAKENHI-PROJECT-21K19501, KAKENHI-PROJECT-21K20647, KAKENHI-PROJECT-23K23860, KAKENHI-PROJECT-23K24373
[Journal Article] Immune cell multiomics analysis reveals contribution of oxidative phosphorylation to B-cell functions and organ damage of lupus2022
- Author(s)
  Takeshima Yusuke、Iwasaki Yukiko、Nakano Masahiro、Narushima Yuta、Ota Mineto、Nagafuchi Yasuo、Sumitomo Shuji、Okamura Tomohisa、Elkon Keith、Ishigaki Kazuyoshi、Suzuki Akari、Kochi Yuta、Yamamoto Kazuhiko、Fujio Keishi
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: - Issue: 6 Pages: 845-853
- DOI
  10.1136/annrheumdis-2021-221464
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02849, KAKENHI-PROJECT-19H03697, KAKENHI-PROJECT-21H02960, KAKENHI-PROJECT-18H05285, KAKENHI-PROJECT-21K19501
[Journal Article] Amino acid signatures of HLA Class-I and II molecules are strongly associated with SLE susceptibility and autoantibody production in Eastern Asians2019
- Author(s)
  Molineros Julio E.、Looger Loren L.、Kim Kwangwoo、Okada Yukinori、Terao Chikashi、Sun Celi、Zhou Xu-jie、Raj Prithvi、Kochi Yuta、Suzuki Akari et al.
- Journal Title
  
  PLOS Genetics
  
  Volume: 15 Issue: 4 Pages: 1008092-1008092
- DOI
  10.1371/journal.pgen.1008092
- NAID
  120006885404
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05285, KAKENHI-PROJECT-18H02849
[Journal Article] Identification of rare coding variants in TYK2 protective for rheumatoid arthritis in the Japanese population and their effects on cytokine signalling2019
- Author(s)
  Motegi Tomoki、Kochi Yuta、Matsuda Koichi、Kubo Michiaki、Yamamoto Kazuhiko、Momozawa Yukihide
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 78 Issue: 8 Pages: 1062-1069
- DOI
  10.1136/annrheumdis-2019-215062
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05285, KAKENHI-PROJECT-18H02849
[Journal Article] PLD4 is a genetic determinant to systemic lupus erythematosus and involved in murine autoimmune phenotypes2019
- Author(s)
  Akizuki S, Ishigaki K, Kochi Y, Law SM, Matsuo K, Ohmura K, Suzuki A, Nakayama M, Iizuka Y, Koseki H, Ohara O, Hirata J, Kamatani Y, Matsuda F, Sumida T, Yamamoto K, Okada Y, Mimori T, Terao C.
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 78 Issue: 4 Pages: 509-518
- DOI
  10.1136/annrheumdis-2018-214116
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09966, KAKENHI-PROJECT-16K09891, KAKENHI-PROJECT-18H05285, KAKENHI-PROJECT-18H02849
[Journal Article] Splicing variant ofWDFY4augments MDA5 signalling and the risk of clinically amyopathic dermatomyositis2018
- Author(s)
  Kochi Yuta et al.
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 77 Issue: 4 Pages: 602-611
- DOI
  10.1136/annrheumdis-2017-212149
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0196, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-17K09966, KAKENHI-PROJECT-18K07542, KAKENHI-PROJECT-18K08307, KAKENHI-PROJECT-16H05341, KAKENHI-PROJECT-16K09902, KAKENHI-PROJECT-16K09907, KAKENHI-PROJECT-18H02849
[Journal Article] olygenic burdens on cell-specific pathways underlie the risk of rheumatoid arthritis2017
- Author(s)
  Ishigaki K, Kochi Y, and et al.
- Journal Title
  
  Nat Genet
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293225
[Journal Article] 関節リウマチ2016
- Author(s)
  高地　雄太
- Journal Title
  
  Clinical Calcium
  
  Volume: 26(4) Pages: 55-59
- Data Source
  KAKENHI-PROJECT-25293225
[Journal Article] Genetics of autoimmune diseases: perspectives from genome-wide association studies.2016
- Author(s)
  Kochi Y
- Journal Title
  
  Int Immunol.
  
  Volume: 28(4) Issue: 4 Pages: 155-161
- DOI
  10.1093/intimm/dxw002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293225
[Journal Article] High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry2016
- Author(s)
  76.Imamura M, Takahashi A, Yamauchi T, Hara K, Yasuda K, ... Okada Y et al.
- Journal Title
  
  Nat Genet
  
  Volume: 48 Issue: 3 Pages: 323-330
- DOI
  10.1038/ng.3496
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14429, KAKENHI-PLANNED-15H05911, KAKENHI-PROJECT-15H05670, KAKENHI-PROJECT-25293225
[Journal Article] Genetics of rheumatoid arthritis in Asia-present and future.2015
- Author(s)
  Yamamoto K, Okada Y, Suzuki A, Kochi Y.
- Journal Title
  
  Nat Rev Rheumatol
  
  Volume: AOP Issue: 6 Pages: 375-379
- DOI
  10.1038/nrrheum.2015.7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293225, KAKENHI-PROJECT-15H05787
[Journal Article] Genetic basis of rheumatoid arthritis: a current review.2014
- Author(s)
  Kochi Y, Suzuki A, Yamamoto K.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 452 Issue: 2 Pages: 254-262
- DOI
  10.1016/j.bbrc.2014.07.085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293225
[Journal Article] 関節リウマチの発症要因と発症メカニズム：遺伝要因2014
- Author(s)
  高地　雄太
- Journal Title
  
  日本臨牀
  
  Volume: 72 Pages: 40-43
- Data Source
  KAKENHI-PROJECT-25293225
[Journal Article] Genetics of rheumatoid arthritis contributes to biology and drug discovery.2014
- Author(s)
  Okada Y, Wu D, Trynka G, Raj T, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, Yoshida S, Graham RR, Manoharan A, Ortmann W, Bhangale T, Denny JC, （省略）, GARNET consortium, （以下省略）.
- Journal Title
  
  Nature
  
  Volume: 506 Issue: 7488 Pages: 376-381
- DOI
  10.1038/nature12873
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22133008, KAKENHI-PROJECT-23221005, KAKENHI-PROJECT-23229007, KAKENHI-PROJECT-24390360, KAKENHI-PROJECT-24592285, KAKENHI-PROJECT-25293225, KAKENHI-PROJECT-26460649, KAKENHI-PROJECT-221S0001
[Journal Article] 自己免疫疾患のゲノム解析2013
- Author(s)
  高地雄太
- Journal Title
  
  Pharma Medica
  
  Volume: 31(1) Pages: 9-12
- Data Source
  KAKENHI-PROJECT-23689051
[Journal Article] A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese2012
- Author(s)
  岡田随象
- Journal Title
  
  PLoS Genetics
  
  Volume: (掲載確定) Issue: 1 Pages: 1002455-1002455
- DOI
  10.1371/journal.pgen.1002455
- NAID
  120005906866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J00226, KAKENHI-PLANNED-19059005, KAKENHI-PROJECT-20689029, KAKENHI-PROJECT-21390299, KAKENHI-PROJECT-21591258, KAKENHI-PROJECT-21591277, KAKENHI-PLANNED-22021023, KAKENHI-PLANNED-22116010, KAKENHI-PROJECT-22591074, KAKENHI-PROJECT-23221005, KAKENHI-PROJECT-23229007, KAKENHI-PROJECT-23590379, KAKENHI-PROJECT-23689051, KAKENHI-PROJECT-24591436
[Journal Article] Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population2012
- Author(s)
  Okada Y, Terao C, Ikari K, Kochi Y,et al
- Journal Title
  
  Nat Genet
  
  Volume: 44(5) Pages: 511-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689051
[Journal Article] ゲノムと免疫疾患2012
- Author(s)
  高地雄太
- Journal Title
  
  最新医学
  
  Volume: 68(3) Pages: 638-647
- Data Source
  KAKENHI-PROJECT-23689051
[Journal Article] Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population2012
- Author(s)
  Okada Y, Kochi Y, et al
- Journal Title
  
  Nature Genetics
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689051
[Journal Article] Functional Variants in NFKBIE and RTKN2 Involved in Activation of the NF-kappaB Pathway Are Associated with Rheumatoid Arthritis in Japanese2012
- Author(s)
  Myouzen K, Kochi Y, Okada Y, Terao C, Suzuki A, Ikari K, Tsunoda T, Takahashi, et al
- Journal Title
  
  PLoS Genet
  
  Volume: 8(9)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689051
[Journal Article] CCR6 遺伝子と関節リウマチ2011
- Author(s)
  高地雄太
- Journal Title
  
  リウマチ科
  
  Volume: 45(5) Pages: 526-530
- Data Source
  KAKENHI-PROJECT-23689051
[Journal Article] 膠原病の疾患感受性遺伝子2011
- Author(s)
  高地雄太
- Journal Title
  
  内科
  
  Volume: 107(4) Pages: 641-644
- Data Source
  KAKENHI-PROJECT-23689051
[Journal Article] 疾患感受性遺伝子とは2011
- Author(s)
  高地雄太
- Journal Title
  
  臨床検査
  
  Volume: 55(11) Pages: 1074-1080
- Data Source
  KAKENHI-PROJECT-23689051
[Journal Article] 新規関節リウマチ感受性遺伝子FCRL32006
- Author(s)
  高地雄太
- Journal Title
  
  臨床免疫 45(3)
  
  Pages: 310-315
- Data Source
  KAKENHI-PROJECT-18790697
[Journal Article] Interactions between IL-32 and tumor necrosis factor alpha contribute to the exacerbation of immune-inflammatory diseases.2006
- Author(s)
  Shoda H, Fujio K, Yamaguchi Y, Okamoto A, Sawada T, Kochi Y, Yamamoto K
- Journal Title
  
  Arthritis Research ＆ Therapy. 8(6)
- Data Source
  KAKENHI-PROJECT-18790697
[Journal Article] 関節リウマチ感受性遺伝子FCRL3の同定2006
- Author(s)
  高地雄太
- Journal Title
  
  臨床免疫 44(6)
  
  Pages: 663-666
- Data Source
  KAKENHI-PROJECT-18790697
[Journal Article] The genetics of systemic lupus erythematosus : differences across ethnicities2006
- Author(s)
  Kochi Y, Shimane K, Yamamoto K
- Journal Title
  
  APLAR Journal of Rheumatology 9(4)
  
  Pages: 353-358
- Data Source
  KAKENHI-PROJECT-18790697
[Journal Article] 関節リウマチ感受性遺伝子FCRL32006
- Author(s)
  高地雄太
- Journal Title
  
  リウマチ科 35 (1)
  
  Pages: 58-62
- Data Source
  KAKENHI-PROJECT-18790697
[Journal Article] 新規関節リウマチ関連遺伝子FCRL32006
- Author(s)
  高地雄太
- Journal Title
  
  医学のあゆみ 217 (7)
  
  Pages: 794-795
- Data Source
  KAKENHI-PROJECT-18790697
[Presentation] 多因子疾患におけるゲノム個別化医療2022
- Author(s)
  高地雄太
- Organizer
  第2回ゲノム医学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19501
[Presentation] 自己免疫疾患のゲノム解析～ゲノム精密医療に向けて～2021
- Author(s)
  高地　雄太
- Organizer
  日本リウマチ学会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02849
[Presentation] eQTL/sQTLから明らかにする多因子疾患の病態2021
- Author(s)
  高地　雄太
- Organizer
  日本オミクス医学会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02849
[Presentation] eQTL/sQTLから明らかにする多因子疾患の病態2021
- Author(s)
  高地　雄太
- Organizer
  日本オミックス医学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19501
[Presentation] What can we learn from eQTL studies in disease genetics?2019
- Author(s)
  Yuta Kochi
- Organizer
  The 4th Symposium of the Inter-University Research Network for Trans-Omics Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02849
[Presentation] 自己免疫疾患感受性多型のsplicing QTL effectを介したtrans-eQTL effectの網羅的評価2018
- Author(s)
  山口健介, 高地雄太, 石垣和慶, 太田峰人, 竹島雄介, 土田優美, 土屋遥香, 住友秀次, 櫻井恵一, 仲地真一郎, 永渕泰雄, 庄田宏文, 藤尾圭志, 山本一彦
- Organizer
  日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-18H02849
[Presentation] GWAS and functional genomics of autoimmune diseases2016
- Author(s)
  Kochi Y
- Organizer
  13th International Congress of Human Genetics
- Place of Presentation
  京都国際会議場
- Year and Date
  2016-04-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293225
[Presentation] Genetics of rheumatoid arthritis: insights from GWAS2014
- Author(s)
  Kochi Y
- Organizer
  日本人類遺伝学会
- Place of Presentation
  東京都・タワーホール船堀
- Year and Date
  2014-11-21
- Invited
- Data Source
  KAKENHI-PROJECT-25293225
[Presentation] 関節リウマチチにおけるゲノムワイド関連解析2011
- Author(s)
  高地雄太
- Organizer
  阿蘇シンポジウム
- Place of Presentation
  阿蘇市
- Year and Date
  2011-07-29
- Data Source
  KAKENHI-PROJECT-23689051
[Presentation] 自己免疫疾患感受性遺伝子FCRL32007
- Author(s)
  高地雄太
- Organizer
  第51回日本リウマチ学会総会・学術集会
- Place of Presentation
  パシフィコ横浜・横浜
- Year and Date
  2007-04-28
- Data Source
  KAKENHI-PROJECT-18790697
[Presentation] ホールゲノム関連解析による関節リウマチ関連遺伝子の同定2007
- Author(s)
  高地雄太
- Organizer
  第52回日本人類遺伝学会
- Place of Presentation
  京王プラザホテル・新宿
- Year and Date
  2007-09-13
- Data Source
  KAKENHI-PROJECT-18790697

1. 猪狩勝則 (80343557)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. MYOUZEN Keiko (80462737)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. Harigai Masayoshi (20238207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 宮井尊史 (40599007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 真下知士 (80397554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 石濱泰 (30439244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SUZUKI Akari

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. OHMURA Koichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. SHODA Hirofumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. TORII Satoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 寺尾知可史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 岡田随象

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
13. 斉藤伸治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 宮冬樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 加藤洋一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 奥西勝秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 山本一彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 住田孝之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kochi Yuta 高地 雄太

KOCHI Yuta 高地 雄太

高地 雄太 コウチ ユウタ

Research Projects

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Co-Researchers

Fuchs角膜内皮変性症に対するゲノム医療の開発

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Pathophysiological study of NMD-targeted transcripts by trans-omics analysisPrincipal Investigator

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AI読影を活用したGWASに基づく関節リウマチにおける関節破壊予測システムの構築

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Dissecting the role of retroelements and their variations in autoimmune diseasesPrincipal Investigator

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A genome-wide association study in Japanese patients with rheumatoid arthritis in order to identify susceptibility loci for Methotrexate-associated lymphoproliferative disorder.

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Dissecting the mechanism of autoimmune diseases using sQTL in immune cellsPrincipal Investigator

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Rare variant analysis of rheumatoid arthritis associated genes.Principal Investigator

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Genetic prediction of Th1 and Th17 cells activity in rheumatoid arthritisPrincipal Investigator

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関節リウマチ感受性遺伝子FCRL3を標的とした創薬のための基盤研究Principal Investigator

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[Journal Article] Munc13-4 regulates asthma and obesity in mice by controlling functions of CD11c+ antigen-presenting cells.2024

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[Journal Article] Attenuation of HOIL-1L ligase activity promotes systemic autoimmune disorders by augmenting linear ubiquitin signaling2024

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[Journal Article] Uncovering the Localization and Function of a Novel Read-Through Transcript ‘TOMM40-APOE’2023

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[Journal Article] Utility of tissue-specific gene expression scores for gene prioritization in Mendelian diseases2022

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Kochi Yuta 高地雄太

KOCHI Yuta 高地雄太

高地雄太コウチユウタ