Kubo Akihito 久保昭仁

… Alternative Names

久保昭仁クボアキヒト

KUBO Akihito 久保昭仁

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Researcher Number	60416245
Other IDs
Affiliation (Current)	2025: 愛知医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2024: 愛知医科大学, 医学部, 教授 2016 – 2019: 愛知医科大学, 医学部, 教授 2012 – 2014: 愛知医科大学, 医学部, 教授 2011: 愛知医科大学, 医学部, 准教授 2008: Clinical Research Center, National Hospital Organization, Kinki-Chuo Chest Medical Center, 臨床研究センター・治験管理研究室, 治験管理研究室長 … More 2008: Clinical Research Center, National Hospital Organization, Kinki-Chuo Chest Medical Center, 治験管理研究室, 室長 2007: Clinical Research Center, National Hospital Organization, Kinki-Chuo Chest Medical Center, 臨床研究センター・治験管理研究室, 室長 2006: 独立行政法人国立病院機構(近畿中央胸部疾患センター臨床研究センター), 政策医療企画研究部治験管理研究室, 室長 Less
Review Section/Research Field	Principal Investigator Tumor biology / Clinical oncology / Respiratory organ internal medicine Except Principal Investigator Basic Section 53040:Nephrology-related
Keywords	Principal Investigator 化学療法 / 癌 / 肺癌 / 薬剤反応性 / 遺伝子 / ゲノム / 次世代シーケンス / ゲノムワイド解析 / 肺がん / 次世代シーケンシング … More / 長期生存 / 中皮腫 / サイトケラチン / FDG-PET / 薬物動態 / 薬力学 / 分子標的治療 / 癌性胸膜炎 / 非小細胞肺癌 / 応用動物 / グラニュライシン / 免疫学 / 免疫療法 … More Except Principal Investigator 妊娠高血圧症候群 / ヒアルロン酸 / 血栓性微小血管症 (TMA) / 内皮細胞 / Glycocalyx Less

Endothelial cell glycocalyx special focus on hyaluronic acid to elucidate the pathogenesis of kidney disease and its clinical application.
- Principal Investigator
  
  伊藤恭彦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Aichi Medical University
Genome-wide analysis for the cure of advanced lung cancerPrincipal Investigator
- Principal Investigator
  
  Kubo Akihito
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Aichi Medical University
Nobel pharmacodynamics evaluation of molecular targeting agents: PHarmacokinetic/PHarmacodynamic Assessment on Malignant Effusions (PHAME)Principal Investigator
- Principal Investigator
  
  KUBO Akihito
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical oncology
- Research Institution
  Aichi Medical University
Analysis of cytotoxic effect of human Granulysin by using novel PK/PD modelPrincipal Investigator
- Principal Investigator
  
  KUBO Akihito
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Clinical Research Center, National Hospital Organization, Kinki-Chuo Chest Medical Center

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2009 2008 2007 Other

All Journal Article Presentation Book

[Book] 肺がん化学療法副作用マネジメントプロのコツ2019
- Author(s)
  加藤俊夫、久保昭仁
- Total Pages
  396
- Publisher
  メジカルビュー
- ISBN
  9784758318051
- Data Source
  KAKENHI-PROJECT-16K07128
[Book] 元気ホスピタル最善の医療をめざして愛知医科大学の最新医療2018
- Author(s)
  久保昭仁
- Total Pages
  213
- Publisher
  南々社
- ISBN
  9784864890786
- Data Source
  KAKENHI-PROJECT-16K07128
[Book] Cytokeratins - Tools in Oncology2012
- Author(s)
  Kubo A, Kanaji N, Bandoh S, Ishii T, Fujita J, Matsunaga T, Yamaguchi E
- Total Pages
  158
- Publisher
  InTech Co.
- Data Source
  KAKENHI-PROJECT-23501314
[Journal Article] Impact of somatic mutations on prognosis in resected non‐small‐cell lung cancer: The Japan Molecular Epidemiology for lung cancer study2020
- Author(s)
  Tamiya Akihiro、Koh Yasuhiro、Isa Shun‐ichi、Kubo Akihito、Ando Masahiko、Saka Hideo、Yoshimoto Naoki、Takeo Sadanori、Adachi Hirofumi、Tagawa Tsutomu、Kawashima Osamu、Yamashita Motohiro、Kataoka Kazuhiko、Takenoyama Mitsuhiro、Takeuchi Yukiyasu、Watanabe Katsuya、Matsumura Akihide、Kawaguchi Tomoya
- Journal Title
  
  Cancer Medicine
  
  Volume: 9 Issue: 7 Pages: 2343-2351
- DOI
  10.1002/cam4.2897
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07128, KAKENHI-PROJECT-17K07176, KAKENHI-PROJECT-18K07443
[Journal Article] Cost-utility analysis of aprepitant for patients who truly need it in Japan2019
- Author(s)
  Tsukiyama Ikuto、Ando Masahiko、Tsukiyama Sumiyo、Takeuchi Masayuki、Ejiri Masayuki、Kurose Yusuke、Saito Hiroko、Arakawa Ichiro、Inoue Tadao、Yamaguchi Etsuro、Kubo Akihito
- Journal Title
  
  Supportive Care in Cancer
  
  Volume: Epub Issue: 10 Pages: 2243-51
- DOI
  10.1007/s00520-019-04672-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07128
[Journal Article] Bicytopenia in Primary Lung Melanoma Treated with Nivolumab2019
- Author(s)
  Takahashi Ayumu、Kubo Akihito、Mizuno Shohei、Kasai Kenji、Asai Nobuhiro、Yonezawa Toshiyuki、Kosaka Kenshi、Nishimura Masaki、Tanaka Hiroyuki、Yokoe Norihito、Tsuzuki Toyonori、Takami Akiyoshi、Yamaguchi Etsuro
- Journal Title
  
  Intern. Med.
  
  Volume: 58 Issue: 6 Pages: 827-831
- DOI
  10.2169/internalmedicine.1011-18
- NAID
  130007612113
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2019-03-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08343, KAKENHI-PROJECT-16K07128
[Journal Article] CCR4 expression in tumor-infiltrating regulatory T cells in patients with squamous cell carcinoma of the lung: A prognostic factor for relapse and survival2019
- Author(s)
  Kubo A, Asai N, Suzuki S, Murotani K, Numanami H, Yoshikawa K, Ueda R, Yamaguchi E
- Journal Title
  
  Cancer Invest
  
  Volume: 37 Issue: 3 Pages: 163-73
- DOI
  10.1080/07357907.2019.1582848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07128, KAKENHI-PROJECT-18K07277, KAKENHI-PROJECT-17K11301
[Journal Article] Small cell lung cancer and interstitial pneumonia associated with anti‐transcriptional intermediary factor‐1γ‐positive dermatomyositis2019
- Author(s)
  Kato Toshio、Ito Satoru、Tsuzuki Toyonori、Watanabe Daisuke、Kubo Akihito、Yamaguchi Etsuro
- Journal Title
  
  Respirology Case Reports
  
  Volume: 7 Issue: 4
- DOI
  10.1002/rcr2.412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07128
[Journal Article] Cost-effectiveness of aprepitant in Japanese patients treated with cisplatin-containing highly emetogenic chemotherapy2018
- Author(s)
  Tsukiyama Ikuto、Hasegawa Shiori、Ikeda Yoshiaki、Takeuchi Masayuki、Tsukiyama Sumiyo、Kurose Yusuke、Ejiri Masayuki、Sakuma Masaki、Saito Hiroko、Arakawa Ichiro、Inoue Tadao、Yamaguchi Etsuro、Kubo Akihito
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 9 Pages: 2881-2888
- DOI
  10.1111/cas.13736
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07128
[Journal Article] Clinical significance of serum anti-GM-CSF autoantibody levels in autoimmune pulmonary alveolar proteinosis2018
- Author(s)
  Nishimura Masaki、Yamaguchi Etsuro、Takahashi Ayumu、Asai Nobuhiro、Katsuda Eisuke、Ohta Toyohiro、Ohtsuka Yoshinori、Kosaka Kenshi、Matsubara Ayako、Tanaka Hiroyuki、Yokoe Norihito、Kubo Akihito、Konno Satoshi、Baba Kenji
- Journal Title
  
  Biomarkers in Medicine
  
  Volume: 12 Issue: 2 Pages: 151-159
- DOI
  10.2217/bmm-2017-0362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07128
[Journal Article] Association between environmental tobacco smoke exposure and the occurrence of EGFR mutations and ALK-rearrangements in never-smokers with non-small cell lung cancer: analyses from a prospective multinational ETS registry2017
- Author(s)
  Kubo A, Soo RA, Ando M, Kawaguchi T, Ahn MJ, Ou S-HI
- Journal Title
  
  Clin Lung Cancer (in press)
  
  Volume: -
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07128
[Journal Article] PIK3CA mutation as a distinctive genetic feature of non-small cell lung cancer with chronic obstructive pulmonary disease: A comprehensive mutational analysis from a multi-institutional cohort2017
- Author(s)
  Sawa Kenji、Koh Yasuhiro、Kawaguchi Tomoya、Kambayashi Satoshi、Asai Kazuhisa、Mitsuoka Shigeki、Kimura Tatsuo、Yoshimura Naruo、Yoshimoto Naoki、Kubo Akihito、Saka Hideo、Matsumura Akihide、Wanibuchi Hideki、Yamamoto Nobuyuki、Nishiyama Noritoshi、Hirata Kazuto
- Journal Title
  
  Lung Cancer
  
  Volume: 112 Pages: 96-101
- DOI
  10.1016/j.lungcan.2017.07.039
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07128, KAKENHI-PROJECT-17K07176, KAKENHI-PROJECT-17K09162, KAKENHI-PROJECT-15K06878, KAKENHI-PROJECT-15K09185, KAKENHI-PROJECT-15K09226
[Journal Article] Association between environmental tobacco smoke exposure and the occurrence of EGFR mutations and ALK-rearrangements in never-smokers with non-small cell lung cancer: analyses from a prospective multinational ETS registry.2017
- Author(s)
  Kubo A, Soo RA, Ando M, Kawaguchi T, Ahn MJ, Ou S-HI
- Journal Title
  
  Clin Lung Cancer
  
  Volume: 18 Issue: 5 Pages: 535-42
- DOI
  10.1016/j.cllc.2017.01.005
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07128, KAKENHI-PROJECT-17K07176
[Journal Article] The ATS/ERS/JRS/ALAT statement "IPF by HRCT" could predict acute exacerbation of interstitial pneumonia in non-small cell lung cancer2017
- Author(s)
  Asai N, Katsuda E, Hamanaka R, Kosaka K, Matsubara A, Nishimura M, Tanaka H, Yokoe N, Takahashi A, Yamaguchi E, Kubo A
- Journal Title
  
  Tumori
  
  Volume: 103 Issue: 1 Pages: 60-65
- DOI
  10.5301/tj.5000574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07128
[Journal Article] Multiplex Ultrasensitive Genotyping of Patients with Non-Small Cell Lung Cancer for Epidermal Growth Factor Receptor (EGFR) Mutations by Means of Picodroplet Digital PCR2017
- Author(s)
  Watanabe Masaru、Kawaguchi Tomoya、Isa Shun-ichi、Ando Masahiko、Tamiya Akihiro、Kubo Akihito、Saka Hideo、Takeo Sadanori、Adachi Hirofumi、Tagawa Tsutomu、Kawashima Osamu、Yamashita Motohiro、Kataoka Kazuhiko、Ichinose Yukito、Takeuchi Yukiyasu、Watanabe Katsuya、Matsumura Akihide、Koh Yasuhiro
- Journal Title
  
  EBioMedicine
  
  Volume: 21 Pages: 86-93
- DOI
  10.1016/j.ebiom.2017.06.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07128, KAKENHI-PROJECT-17K07176, KAKENHI-PROJECT-15K06878
[Journal Article] Interstitial Lung Disease after Pleurodesis for Malignant Pleural Effusion2017
- Author(s)
  Yokoe Y, Katsuda E, Kosaka K, Hamanaka R, Matsubara A, Nishimura M, Tanaka H, Asai N, Takahashi A, Kawamura T, Ishiguchi T, Yamaguchi E, Kubo A
- Journal Title
  
  Internal Medicine (in press)
  
  Volume: -
- NAID
  130005773833
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07128
[Journal Article] Prospective analysis on oncogenic driver mutations and environmental factors: Japan Molecular Epidemiology for lung cancer study (JME)2016
- Author(s)
  2.Tomoya Kawaguchi, Yasuhiro Koh, Masahiko Ando, Norimasa Ito, Sadanori Takeo, Hirofumi Adachi, Tsutomu Tagawa, Seiichi Kakegawa, Motohiro Yamashita, Kazuhiko Kataoka, Yukito Ichinose, Yukiyasu Takeuchi, Masakuni Serizawa, Akihiro Tamiya, Shigeki Shimizu, Naoki Yoshimoto, Akihito Kubo, Shun-ichi Isa, Hideo Saka
- Journal Title
  
  J Clin Oncol
  
  Volume: 34 Issue: 19 Pages: 2247-2257
- DOI
  10.1200/jco.2015.64.2322
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460896, KAKENHI-PROJECT-16K07128, KAKENHI-PROJECT-15K06893
[Journal Article] Reply to G Spitzer, et al; F Zhou,et al; and B Biswas.2015
- Author(s)
  Kawaguchi T, Ando M, Kubo A.
- Journal Title
  
  J Clin Oncol
  
  Volume: 33 Issue: 5 Pages: 526-7
- DOI
  10.1200/jco.2014.58.5315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314
[Journal Article] Metastatic Embryonal Carcinoma Mimicking Locally Advanced Non-small Cell Lung Cancer2015
- Author(s)
  Numanami H, Takahashi D, Takahashi E, Katsuda E, Kamei S, Naruse N, Baba K, Haniuda M, Yokoi T, Yamaguchi E, Kubo A.
- Journal Title
  
  Intern. Med.
  
  Volume: 54 Issue: 1 Pages: 59-61
- DOI
  10.2169/internalmedicine.54.2884
- NAID
  130004902986
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23501314
[Journal Article] Therapeutic and Preventive Antiemetic Effect of Aprepitant in Japanese Patients with Thoracic Malignancies Who Truly Need It.2015
- Author(s)
  Ito S, Tsukiyama I, Ando M, Katakami M, Hamanaka R, Kosaka K, Matsubara A, Nishimura M, Tanaka H, Asai N, Yokoe N, Takahashi A, Baba K, Matsuura K, Yamaguchi E, Kubo A.
- Journal Title
  
  Support Care Cancer
  
  Volume: 23 Issue: 4 Pages: 905-12
- DOI
  10.1007/s00520-014-2430-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314, KAKENHI-PROJECT-25460896
[Journal Article] The role of smoking status on the progression-free survival of non-small-cell lung cancer patients harboring activating epidermal growth factor (EGFR) mutations receiving first-line EGFR tyrosine kinase inhibitor: a meta-analysis of prospective randomized trials.2015
- Author(s)
  Hasegawa Y, Ando M, Maemondo M, Yamamoto S, Isa S, Saka H, Kubo A, Kawaguchi T, Takada M, Rosell R, Kurata T, Ou SH.
- Journal Title
  
  The Oncologist
  
  Volume: 20 Issue: 3 Pages: 1-9
- DOI
  10.1634/theoncologist.2014-0285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314, KAKENHI-PROJECT-15K09237, KAKENHI-PROJECT-25460896
[Journal Article] Ultra-sensitive detection of the pretreatment EGFR T790M mutation in non-small-cell lung cancer patients with an EGFR-activating mutation using picodroplet digital PCR.2015
- Author(s)
  Watanabe M, Kawaguchi T, Isa S-I, Ando M, Tamiya A, Kubo A, Saka H, Takeo S, Adachi H, Tagawa T, Kakegawa S, Yamashita M, Kataoka K, Ichinose Y, Takeuchi Y, Sakamoto K, Matsumura A, Koh Y.
- Journal Title
  
  Clin Cancer Res
  
  Volume: in press Issue: 15 Pages: 3552-3560
- DOI
  10.1158/1078-0432.ccr-14-2151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314, KAKENHI-PROJECT-25460896
[Journal Article] Successful crizotinib re-challenge after crizotinib-induced organizing pneumonia in anaplastic lymphoma kinase-rearranged non-small cell lung cancer.2014
- Author(s)
  Asai N, Yokoi T, Yamaguchi E, Kubo A.
- Journal Title
  
  Case Reports in Oncology
  
  Volume: 7 Issue: 3 Pages: 681-4
- DOI
  10.1159/000366516
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314
[Journal Article] Long-term Complete Response in a Patient with Disseminated Pulmonary Pleomorphic Carcinoma Induced by Cisplatin and Gemcitabine2014
- Author(s)
  Tamiya A, Asami K, Shimizu S, Matusmura A, Isa S-I, Okishio K, Kitaichi M, Atagi S, Takada M, Kawaguchi T, Kubo A.
- Journal Title
  
  Intern. Med.
  
  Volume: 53 Issue: 22 Pages: 2625-2628
- DOI
  10.2169/internalmedicine.53.2637
- NAID
  130004713245
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23501314
[Journal Article] Randomized phase III trial of erlotinib versus docetaxel as second- or third-line therapy in patients with advanced non-small cell lung cancer: Docetaxel and Erlotinib Lung cancer TriAl (DELTA).2014
- Author(s)
  Kawaguchi T, Ando M, Asami K, Okano Y, Fukuda M, Nakagawa H, Ibata H, Kozuki T, Endo T, Tamura A, Kamimura M, Sakamoto K, Yoshimi M, Soejima Y, Tomizawa Y, Isa S, Takada M, Saka H, Kubo A.
- Journal Title
  
  J Clin Oncol
  
  Volume: 32 Issue: 18 Pages: 1902-8
- DOI
  10.1200/jco.2013.52.4694
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314, KAKENHI-PROJECT-25460896
[Journal Article] Successful crizotinib re-challenge after crizotinib-induced interstitial lung disease in patients with advanced non-small cell lung cancer.2014
- Author(s)
  Asai N, Yamaguchi E, Kubo A
- Journal Title
  
  Clin Lung Cancer (in press)
  
  Volume: na
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314
[Journal Article] Long-term complete response in a patient with disseminated pulmonary pleomorphic carcinoma induced by cisplatin and gemcitabine.2014
- Author(s)
  Tamiya A, Asami K, Shimizu S, Matusmura A, Isa S-I, Okishio K, Kitaichi M, Atagi S, Takada M, Kawaguchi T, Kubo A
- Journal Title
  
  Internal Medicine (in press)
  
  Volume: na
- NAID
  130004713245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314
[Journal Article] Successful crizotinib re-challenge after crizotinib-induced interstitial lung disease in patients with advanced non-small cell lung cancer.2014
- Author(s)
  Asai N, Yamaguchi E, Kubo A.
- Journal Title
  
  Clin Lung Cancer
  
  Volume: 15 Issue: 3 Pages: e33-e35
- DOI
  10.1016/j.cllc.2013.12.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314
[Journal Article] Role of consolidation chemotherapy after concurrent chemo-radiotherapy in locally advanced non-small-cell lung cancer.2014
- Author(s)
  Tsujino K, Kurata T, Kawaguchi T, Kubo A, Takada M, Ando M.
- Journal Title
  
  J Thorac Oncol
  
  Volume: 9 Issue: 1 Pages: e7-e8
- DOI
  10.1097/jto.0000000000000035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314, KAKENHI-PROJECT-25460896
[Journal Article] Human papilloma virus in non-small cell lung cancer in never smokers: A systematic review of the literature.2014
- Author(s)
  Hasegawa Y, Ando M, Kubo A, Isa SI, Yamamoto S, Tsujino K, Kurata T, Ou SH, Takada M, Kawaguchi T
- Journal Title
  
  Lung Cancer
  
  Volume: 8 Issue: 1 Pages: 8-13
- DOI
  10.1016/j.lungcan.2013.10.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314, KAKENHI-PROJECT-25460896
[Journal Article] Randomized phase III trial of erlotinib versus docetaxel as second- or third-line therapy in patients with advanced non-small cell lung cancer: Docetaxel and Erlotinib Lung cancer TriAl (DELTA).2014
- Author(s)
  Kawaguchi T, Ando M, Asami K, Okano Y, Fukuda M, Nakagawa H, Ibata H, Kozuki T, Endo T, Tamura A, Kamimura M, Sakamoto K, Yoshimi M, Soejima Y, Tomizawa Y, Isa S, Takada M, Saka H, Kubo A
- Journal Title
  
  J Clin Oncol (in press)
  
  Volume: na
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314
[Journal Article] Rationale and Design of the Japan Molecular Epidemiology for Lung Cancer Study2013
- Author(s)
  Kawaguchi T, Ando M, Ito N, Isa SI, Tamiya A, Shimizu S, Saka H, Kubo A, Koh Y, Matsumura A
- Journal Title
  
  Clin Lung Cancer
  
  Volume: 14 Issue: 5 Pages: 596-600
- DOI
  10.1016/j.cllc.2013.03.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314, KAKENHI-PROJECT-24501363, KAKENHI-PROJECT-25460896
[Journal Article] Is Consolidation Chemotherapy after Concurrent Chemo-Radiotherapy Beneficial for Patients with Locally Advanced Non-Small-Cell Lung Cancer?: A Pooled Analysis of the Literature.2013
- Author(s)
  Tsujino K, Kurata T, Yamamoto S, Kawaguchi T, Kubo A, Isa S, Hasegawa Y, Ou SH, Takada M, Ando M
- Journal Title
  
  J Thorac Oncol
  
  Volume: 8 Issue: 9 Pages: 1181-9
- DOI
  10.1097/jto.0b013e3182988348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314, KAKENHI-PROJECT-25460896
[Journal Article] EGFR R497K polymorphism is a favorable prognostic factor for advanced lung cancer2009
- Author(s)
  Sasaki H, Kubo A, Fujii Y, et al.
- Journal Title
  
  J Cancer Res Clin Oncol 135
  
  Pages: 313-318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590875
[Journal Article] A novel EGFR mutation D1012H and polymorphism at exon 25 in Japanese lung cancer2008
- Author(s)
  Sasaki H, Kubo A, Fujii Y, et al.
- Journal Title
  
  J Cancer Res Clin Oncol 134
  
  Pages: 13372-13376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590875
[Journal Article] Full-Length Cytokeratin 8 Is Released and Circulates in Patients with Non-Small Cell Lung Cancer2008
- Author(s)
  Ishii T, Kubo A, et al.
- Journal Title
  
  Tumor Biology 29
  
  Pages: 57-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590875
[Journal Article] Compensation of type I and type II cytokeratin pools in lung cancer2007
- Author(s)
  Kanaji N, Kubo A, et al.
- Journal Title
  
  Lung Cancer 55
  
  Pages: 295-302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590875
[Presentation] The safety assessment of crizotinib and alectinib from real-world data of 840 ALK-inhibitor naive patients with NSCLC harboring ALKrearrangement (WJOG9516L).2019
- Author(s)
  Kunimasa K, Ito K, Yamanaka T, Fujimoto D, Mori M, Maeno K, Tomomatsu K, Tamura A, Tanaka H, Watanabe S, Teraoka S, Hataji O, Suzuki K, Hontsu S, Hara S, Bessho A, Kubo A, Okuno M, Nakagawa K, Yamamoto N.
- Organizer
  European Society of Medical Oncology (ESMO) Congress, Barcelona, Spain. September, 2019.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07128
[Presentation] Diagnostic and prognostic impact of serum procalcitonin in non-small cell lung cancer.2019
- Author(s)
  Kajikawa S, Ohashi W, Yonezawa T, Kosaka K, Kato T, Tanaka H, Ito S, Yamaguchi E, Kubo A.
- Organizer
  24th Asian Pacific Society of Respirology. Hanoi, Vietnam. November 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07128
[Presentation] Impact of somatic mutations on recurrence free survival (RFS) and overall survival (OS) for resected non-small cell lung cancer (NSCLC): results from the Japan Molecular Epidemiology for lung cancer study (JME).2018
- Author(s)
  Tamiya A, Koh Y, Kubo A, Ando M, Isa SI, Saka H, Yoshimoto N, Serizawa M, Takeo S, Adachi H, Tagawa T, Kawashima O, Yamashita M, Kataoka K, Ichinose Y, Takeuchi Y, Watanabe K, Matsumura A, Kawaguchi T.
- Organizer
  Annual Meeting of the American Society of Clinical Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07128
[Presentation] Cost-effectiveness analysis of aprepitant in Japanese patients who received high-dose cisplatin.2018
- Author(s)
  Tsukiyama I, Hasegawa S, Ikeda Y, Takeuchi M, Tsukiyama S, Kurose Y, Ejiri M, Sakuma M, Saito H, Arakawa I, Inoue T, Yamaguchi E, Kubo A.
- Organizer
  Annual Meeting of the American Society of Clinical Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07128
[Presentation] Impact of de novo T790M on outcome for resected NSCLC from EGFR mutant cohort of Japan Molecular Epidemiology (JME) study2018
- Author(s)
  Matsumoto Y, Kawaguchi T, Sawa K, Watanabe M, Isa S-I, Ando M, Tamiya A, Kubo A, Saka H, Matsumura A, Koh Y
- Organizer
  19th World Conference on Lung Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07128
[Presentation] Low detection rate of EGFR driver and T790M mutations in plasma by cobas EGFR Mutation Test v2 after acquired resistance to afatinib2018
- Author(s)
  Oya Y, Yoshida T, Asada K, Oguri T, Inui N, Morikawa S, Ito K, Kimura T, Matsui T, Kubo A, Kato T, Shindo J, Tsuda T, Hida T
- Organizer
  International Association for Studying Lung Cancer (IASLC) Asia Conference on Lung Cancere 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07128
[Presentation] Impact of somatic mutations on recurrence free survival (RFS) and overall survival (OS) for resected non-small cell lung cancer (NSCLC): results from the Japan Molecular Epidemiology for lung cancer study (JME)2018
- Author(s)
  Tamiya A, Koh Y, Kubo A, Ando M, Isa SI, Saka H, Yoshimoto N, Serizawa M, Takeo S, Adachi H, Tagawa T, Kawashima O, Yamashita M, Kataoka K, Ichinose Y, Takeuchi Y, Watanabe K, Matsumura A, Kawaguchi T
- Organizer
  Annual Meeting of the American Society of Clinical Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07128
[Presentation] Impacts of environmental tobacco smoke on EGFR mutations and ALK rearrangements in never smokers with non-small cell lung cancer: Analyses on a prospective multinational ETS registry.2013
- Author(s)
  Kubo A, Ando M, Soo RA, Kawaguchi T, Ou S-HI, Ahn M-J.
- Organizer
  15th World Conference on Lung Cancer
- Place of Presentation
  Sydney, Australia
- Data Source
  KAKENHI-PROJECT-23501314
[Presentation] Therapeutic and preventive effects of aprepitant for chemotherapy-induced nausea and vomiting in Japanese patients with thoracic malignancies.2013
- Author(s)
  Ito S, Tsukiyama I, Ando M, Tanahashi M, Hamanaka R, Kosaka K, Matsubara A, Nishimura M, Tanaka H, Asai N, Yokoe N, Takahashi A, Baba K, Matsuura K, Yamaguchi E, Kubo A.
- Organizer
  15th World Conference on Lung Cancer
- Place of Presentation
  Sydney, Australia
- Data Source
  KAKENHI-PROJECT-23501314
[Presentation] Impact of environmental tobacco smoke (ETS) on ALK rearrangements in never smokers (NS) with non-small cell lung cancer (NSCLC): Analyses on a prospective multinational ETS registry.2013
- Author(s)
  Kubo A, Ando M, Soo RA, Kawaguchi T, Ou S-HI, Ahn M-J.
- Organizer
  Annual Meeting of the American Society of Clinical Oncology
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-23501314
[Presentation] Randomized phase III trial of erlotinib (E) versus (v) docetaxel (D) as second or third line therapy in patients with advanced non-small cell lung cancer (NSCLC) who have wild type or mutant epidermal growth factor receptor (EGFR): Docetaxel and Erlotinib Lung cancer TriAl (DELTA).2013
- Author(s)
  Okano Y, Ando M, Asami K, Fukuda M, Nakagawa H, Ibata H, Kozuki T, Endo T, Tamura A, Kamimura M, Sakamoto K, Yoshimi M, Soejima Y, Tomizawa Y, Isa S, Takada M, Saka H, Kubo A, Kawaguchi T.
- Organizer
  Annual Meeting of the American Society of Clinical Oncology
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-23501314
[Presentation] Cytokeratin (CK) 8: the dominant type II intermediate filament protein in non-small cell lung cancer (NSCLC).2012
- Author(s)
  Kubo A
- Organizer
  第52回日本呼吸器学会
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-23501314
[Presentation] Malignant pleural effusions as a model for pharmacodynamics studies.2011
- Author(s)
  久保昭仁
- Organizer
  Osaka Lung Cancer Expert Meeting(招待講演)
- Place of Presentation
  大阪府堺市
- Data Source
  KAKENHI-PROJECT-23501314
[Presentation] 非小細胞肺癌(NSCLC)の癌性胸膜炎(MPE)におけるゲフィチニブの薬力学・薬物動態・臨床第II相試験2011
- Author(s)
  久保昭仁、洪　泰浩、堀　隆、伊佐俊一、福岡順也、川口知哉、安藤昌彦、岡本　勇、北市正則、安宅信二、河原正明、楠　洋子、山口悦郎、中川和彦、高田　實
- Organizer
  第51回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23501314
[Presentation] Updated overall survival (OS) results of randomized phase III trial of erlotinib (E) versus (v) docetaxel (D) as second or third line therapy in patients with advanced non-small cell lung cancer (NSCLC): Docetaxel and Erlotinib Lung cancer TriAl (DELTA).
- Author(s)
  Ibata H, Ando M, Asami K, Okano Y, Fukuda M, Nakagawa H, Kozuki T, Endo T, Tamura A, Kamimura M, Sakamoto K, Yoshimi M, Soejima Y, Tomizawa Y, Isa S, Takada M, Saka H, Kubo A, Kawaguchi T.
- Organizer
  Annual Meeting of the American Society of Clinical Oncology
- Place of Presentation
  Chicago, IL, USA.
- Year and Date
  2014-05-30 – 2014-06-03
- Data Source
  KAKENHI-PROJECT-23501314
[Presentation] The role of smoking status on the progression-free survival of non-small-cell lung cancer patients harboring activating epidermal growth factor (EGFR) mutations receiving first-line EGFR tyrosine kinase inhibitor: a meta-analysis of prospective randomized trials.
- Author(s)
  Hasegawa Y, Ando M, Maemondo M, Yamamoto S, Isa S, Saka H, Kubo A, Kawaguchi T, Takada M, Kurata T, Ou SH.
- Organizer
  Annual Meeting of the American Society of Clinical Oncology
- Place of Presentation
  Chicago, IL, USA.
- Year and Date
  2014-05-30 – 2014-06-03
- Data Source
  KAKENHI-PROJECT-23501314

1. TAKADA Minoru (20373516)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
2. OKADA Masaji (40160684)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. KAWAHARA Masaaki (30344352)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KOU Yasuhiro (80426519)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
5. FUKUOKA Junya (00324575)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. KAWAGUCHI Tomoya (70254422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
7. ISA Shun-Ichi (60421913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
8. 伊藤恭彦 (60402632)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 石本卓嗣 (00534835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 水野正司 (20303638)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 安藤昌彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kubo Akihito 久保 昭仁

久保 昭仁 クボ アキヒト

KUBO Akihito 久保 昭仁

Research Projects

Research Products

Co-Researchers

Endothelial cell glycocalyx special focus on hyaluronic acid to elucidate the pathogenesis of kidney disease and its clinical application.

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Genome-wide analysis for the cure of advanced lung cancerPrincipal Investigator

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Nobel pharmacodynamics evaluation of molecular targeting agents: PHarmacokinetic/PHarmacodynamic Assessment on Malignant Effusions (PHAME)Principal Investigator

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Analysis of cytotoxic effect of human Granulysin by using novel PK/PD modelPrincipal Investigator

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[Book] 肺がん化学療法副作用マネジメント プロのコツ2019

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[Book] 元気ホスピタル 最善の医療をめざして 愛知医科大学の最新医療2018

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[Book] Cytokeratins - Tools in Oncology2012

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[Journal Article] Impact of somatic mutations on prognosis in resected non‐small‐cell lung cancer: The Japan Molecular Epidemiology for lung cancer study2020

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[Journal Article] Cost-utility analysis of aprepitant for patients who truly need it in Japan2019

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[Journal Article] Bicytopenia in Primary Lung Melanoma Treated with Nivolumab2019

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[Journal Article] CCR4 expression in tumor-infiltrating regulatory T cells in patients with squamous cell carcinoma of the lung: A prognostic factor for relapse and survival2019

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[Journal Article] Small cell lung cancer and interstitial pneumonia associated with anti‐transcriptional intermediary factor‐1γ‐positive dermatomyositis2019

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[Journal Article] Cost-effectiveness of aprepitant in Japanese patients treated with cisplatin-containing highly emetogenic chemotherapy2018

Author(s)

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DOI

Kubo Akihito 久保昭仁

久保昭仁クボアキヒト

KUBO Akihito 久保昭仁

[Book] 肺がん化学療法副作用マネジメントプロのコツ2019

[Book] 元気ホスピタル最善の医療をめざして愛知医科大学の最新医療2018