YANAGISAWA Hiroko 柳澤比呂子

Researcher Number	60416659
Other IDs
Affiliation (based on the past Project Information) *help	2016 – 2019: 一般財団法人脳神経疾患研究所, 先端医療研究センター, 研究員 2015: 一般財団法人脳神経疾患研究所, その他部局等, 研究員 2015: 公益財団法人東京都医学総合研究所, 運動・感覚システム研究分野, 研究員 2014: 公益財団法人東京都医学総合研究所, 運動・感覚システム分野, 研究員 2013: 公益財団法人東京都医学総合研究所, 運動・感覚システム研究分野, 研究員 … More 2008: (財)東京都医学研究機構, 東京都神経科学総合研究所, 研究員 2008: 財団法人東京都医学研究機構, 東京都神経科学総合研究所, 研究員 2007: 東京都神経科学総合研究所, 研究員 Less
Review Section/Research Field	Principal Investigator Experimental pathology Except Principal Investigator Pediatrics / Neurochemistry/Neuropharmacology
Keywords	Principal Investigator Spin1 / mTOR / SPNS1/Spin1 / NPC / ライソゾーム / シュワン細胞株 / ニーマンピック病C型 / ライソゾーム病 / LC3 / Spin1/SPNS / p62 / ロイシン / オートファジー … More Except Principal Investigator … More iPS細胞 / lysosomal disease / MS/MS / iPS cells / ライソゾーム病 / NPC病 / プロテオミクス / iPS細胞作製 / ニーマンピック病 / ゴーシェ病 / TEM解析 / oxysterol / lysoGb3 / 蓄積脂質 / Niemann-Pick C病 / タンデムMS / オキシステロール、 / バイオマーカー / ファブリ病 / NPC / 電子顕微鏡 / Nestin / GM2-ganglioside / 細胞治療 / Miglustat / 神経細胞 / ポンぺ病 / Tay-Sacks病 / Pompe disease / Niemann-Pick disease / Fabry sisease / Tay-Sacks disease / MLD / Fabry 病 / Niemann-Pick病 / Tay-Sacks 病 / IPS 細胞 / 神経組織養 / ガレクチン-3 / ガレクチン-1 / グリア細胞株由来神経栄養因子 / シグナル伝達系 / 毛様体神経栄養因子 / 脊髄後根神経節細胞 / 軸索再生 / 神経細胞死制御 / シュワン細胞 / 後根神経節(DRG)ニューロン / グリア細胞株由来神経栄養因子(GDNF) / 神経成長因子(NGF) / ガレクチン-1(GAL-1) / 毛様態神経栄養因子(CNTF) Less

Pathogenesis, Diagnosis and treatment of lysosomal diseases by Biomarker Analysis
- Principal Investigator
  
  Eto Yoshikatsu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Southen Tohoku Research Institute for Neuroscience
Pathogenetic Stidies and Novel Enzyme Treatment using Fabry, Pompe and Tay-Sacks iPS cells
- Principal Investigator
  
  Eto Yoshikatsu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Southen Tohoku Research Institute for Neuroscience
Does Spin1 mediate L-leucine-effects to ameliorate impaired autophagy?Principal Investigator
- Principal Investigator
  
  YANAGISAWA Hiroko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Mechanisms of gene regulation and action of neuroprotective factors
- Principal Investigator
  
  SANGO Kazunori
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research

All 2020 2019 2018 2017 2016 2015 2014 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Dysregulated DNA methylation of GLA gene was associated with dysfunction of autophagy.2019
- Author(s)
  Yanagisawa H, Hossain MA, Miyajima T, Nagao K, Miyashita T, Eto Y.
- Journal Title
  
  Molecular Genetics Metabolism
  
  Volume: S1096-7192(19) Pages: 30014-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10067
[Journal Article] Future clinical and biochemical predictions of Fabry disease in females by methylation studies of the GLA gene.2019
- Author(s)
  Hossain MA, Wu C, Yanagisawa H, Miyajima T, Akiyama K, Eto Y.
- Journal Title
  
  Mol. Genet. Metab. Rep.
  
  Volume: 2019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10067
[Journal Article] Characteristics of PPT1 and TPP1 enzymes in neuronal ceroid lipofuscinosis (NCL) 1 and 2 by dried blood spots (DBS) and leukocytes and their application to newborn screening.2018
- Author(s)
  Itagaki R, Endo M, Yanagisawa H, Hossain MA, Akiyama K, Yaginuma K, Miyajima T, Wu C, Iwamoto T, Igarashi J, Kobayashi Y, Tohyama J, Iwama K, Matsumoto N, Shintaku H, Eto Y.
- Journal Title
  
  Mol Genet Metab.
  
  Volume: S1096-7192(18) Issue: 1 Pages: 30154-9
- DOI
  10.1016/j.ymgme.2018.03.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10067, KAKENHI-PROJECT-17H01539
[Journal Article] Characteristics of PPT1 and TPP1 enzymes in neuronal ceroid lipofuscinosis (NCL) 1 and 2 by dried blood spots (DBS) and leukocytes and their application to newborn screening.2018
- Author(s)
  5.Itagaki R, Endo M, Yanagisawa H, Hossain MA, Akiyama K, Yaginuma K, Miyajima T, Wu C, Iwamoto T, Igarashi J, Kobayashi Y, Tohyama J, Iwama K, Matsumoto N, Shintaku H, Eto Y.
- Journal Title
  
  Mol Genet Metab.
  
  Volume: 2018 May;124(1) Pages: 64-70
- Data Source
  KAKENHI-PROJECT-17K10067
[Journal Article] The severe clinical phenotype for a heterozygous Fabry female patient correlates to the methylation of non-mutated allele associated with chromosome 10q26 deletion syndrome.2017
- Author(s)
  Hossain MA, Yanagisawa H, Miyajima T, Wu C, Takamura A, Akiyama K, Itagaki R, Eto K, Iwamoto T, Yokoi T, Kurosawa K, Numabe H, Eto Y.
- Journal Title
  
  Molecular Genetics and Metabolism
  
  Volume: 120 Issue: 3 Pages: 173-179
- DOI
  10.1016/j.ymgme.2017.01.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26870831, KAKENHI-PROJECT-17K10067
[Journal Article] The severe clinical phenotype for a heterozygous Fabry female patient correlates to the methylation of non-mutated allele associated with chromosome 10q26 deletion syndrome.2017
- Author(s)
  Hossain MA, Yanagisawa H, Miyajima T, Wu C, Takamura A, Akiyama K, Itagaki R, Eto K, Iwamoto T, Yokoi T, Kurosawa K, Numabe H, Eto Y
- Journal Title
  
  Mol Genet Metab.
  
  Volume: 120(3) Pages: 173-179
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461536
[Journal Article] L-leucine and SPNS1 coordinately ameliorate dysfunction of autophagy in mouse and human Niemann-Pick type C disease.2017
- Author(s)
  Yanagisawa H, Ishii T, Endo K, Kawakami E, Nagao K, Miyashita T, Akiyama K, Watabe K, Komatsu M, Yamamoto D, Eto Y.
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 15994-15994
- DOI
  10.1038/s41598-017-15305-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06763, KAKENHI-PROJECT-17K10061, KAKENHI-PROJECT-17K10067, KAKENHI-PROJECT-17K19371, KAKENHI-PUBLICLY-17H05935, KAKENHI-PLANNED-25111006, KAKENHI-PROJECT-16H06371, KAKENHI-PROJECT-15K09729
[Journal Article] Application of a diagnostic methodology by quantification of 26:0　lysophosphatidylcholine in dried blood spots for Japanese newborn screening of X-linked adrenoleukodystrophy.2017
- Author(s)
  Wu C, Iwamoto T, Igarashi J, Miyajima T, Hossain MA, Yanagisawa H, Akiyama K, Shintaku H, Eto Y.
- Journal Title
  
  Mol Genet Metab Rep.
  
  Volume: １１ Pages: 115-118
- DOI
  10.1016/j.ymgmr.2017.06.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10067
[Journal Article] Ten-year-long enzyme replacement therapy shows a poor effect in alleviating giant leg ulcers in a male with Fabry disease.2017
- Author(s)
  Okada J, Hossain MA, Wu C, Miyajima T, Yanagisawa H, Akiyama K, Eto Y.
- Journal Title
  
  Mol Genet Metab Rep.
  
  Volume: 14 Pages: 68-72
- DOI
  10.1016/j.ymgmr.2017.12.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10067
[Journal Article] Adenoviral expression of TDP-43 and FUS genes and shRNAs for protein degradation pathways in rodent motoneurons in vitro and in vivo.2014
- Author(s)
  Watabe K, Akiyama K, Kawakami E, Ishii T, Endo K, Yanagisawa H, Sango K, Tsukamoto M.
- Journal Title
  
  Neuropathology
  
  Volume: 34 Issue: 1 Pages: 83-98
- DOI
  10.1111/neup.12058
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24500428, KAKENHI-PROJECT-25430056, KAKENHI-PROJECT-25460510
[Journal Article] Differential effects of high glucose and methylglyosal on viability and polvol metabolism in immortalized adult mouse Schwann cells2008
- Author(s)
  Sango K., Yanagisawa H., Kato K, Kato N, Hirooka H, Watanabe, K.
- Journal Title
  
  Open Diabetes J 1
  
  Pages: 1-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500337
[Journal Article] Neuroprotective properties of ciliary neurotrophic factor for cultured adult rat dorsal root ganglion neurons.2008
- Author(s)
  Sango K, Yanagisawa H, Komuta Y, Si Y, Kawano H.
- Journal Title
  
  Histochem Cell Biol 140
  
  Pages: 669-679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500337
[Journal Article] Neuroprotective properties of ciliary neurotrophic factor for cultured adult rat dorsal root ganglion neurons2008
- Author(s)
  Sango K, Yanagisawa H, Komuta Y, Si Y, Kawano H.
- Journal Title
  
  Histochemistry and Cell Biology 140
  
  Pages: 669-679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500337
[Journal Article] Differential effects of high glucose and methylglyoxal on viability and polyol metabolism in immortalized adult mouse Schwann cells2008
- Author(s)
  Sango K, Yanagisawa H, Kato K, Kato N, Hirooka H, Watabe K.
- Journal Title
  
  Open Diabetes Journal 1
  
  Pages: 1-11
- NAID
  10025625337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500337
[Journal Article] Expression and histochemical localization of ciliary neurotrophic factor in cultured adult rat dorsal root ganglion neurons.2007
- Author(s)
  Sango K., Yanagisawa H., Takaku S.
- Journal Title
  
  Histochemistry and Cell Biology 128
  
  Pages: 35-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500337
[Journal Article] Expression and histochemical localization of ciliary neurotrophic factor (CNTF) mRNA/protein in cultured adult rat dorsal root ganglion neurons.2007
- Author(s)
  Sang K, Yanagisawa H, Takaku S.
- Journal Title
  
  Histochem Cell Biol 128
  
  Pages: 35-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] DNA methylation study of GLA gene and its association with autophagy and clinical severity of heterozygous Fabry disease females.2020
- Author(s)
  M. Arif Hossain, Wu Chen, Yanagisawa H., Miyajima T., Saito R., Akiyama K., Eto Y.
- Organizer
  World sy,mposiu, 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10067
[Presentation] Future clinical and biochemical predictions of Fabry disease in females by methylation studies of the GLA gene.; M. Arif Hossain2019
- Author(s)
  M. Arif Hossain, Wu Chen, Yanagisawa H., Miyajima T., Akiyama K., Saito R., Eto Y
- Organizer
  The 61st Annual Meeting of the Japanese Society for Inherited Metabolic Diseases
- Data Source
  KAKENHI-PROJECT-17K10067
[Presentation] 重度ヘテロ結合Fabry女性の予測診断に向けたメチル化に関する研究2017
- Author(s)
  Mohammad Arif Hossain, Chen Wu, 宮島任司, 柳澤比呂子, 秋山けい子, 岩本武夫, 衞藤義勝.
- Organizer
  日本人類遺伝学会　第62回大会
- Data Source
  KAKENHI-PROJECT-17K10067
[Presentation] ファブリー病患者の年齢、性別、及び酵素補充療法に起因する抗体価と血漿中LysoGb3の相関関係2017
- Author(s)
  Chen Wu, 岩本武夫, Mohammad Arif Hossain, 宮島任司, 秋山けい子, 柳澤比呂子, 五十嵐純子, 衞藤義勝
- Organizer
  日本先天代謝異常学会
- Data Source
  KAKENHI-PROJECT-17K10067
[Presentation] 乾燥濾紙血（DBS）を用いたムコ多糖症Ⅶ型（MPS Ⅶ）のハイリスクスクリーニングの検討2017
- Author(s)
  宮島任司, 五十嵐純子, Chen Wu, 柳澤比呂子, Mohammad Arif Hossain,　秋山けい子, 濱﨑考史, 岩本武夫, 衞藤義勝
- Organizer
  日本先天代謝異常学会
- Data Source
  KAKENHI-PROJECT-17K10067
[Presentation] Application of Lysosphingomyelin Measuremane for Diagonosis of Japanese patients with Niemann Pick Type C by MS/MS.2017
- Author(s)
  Chen Wu, 岩本武夫, 柳澤比呂子, 秋山けい子, 宮島任司, 五十嵐純子, Mohammad Arif Hossain, 衞藤義勝。
- Organizer
  第22回日本ライソゾーム病研究会
- Data Source
  KAKENHI-PROJECT-17K10067
[Presentation] ニーマンピックC型の診断バイオマーカー：血清Lysosphongomyelin 測定の有用性に関する研究2017
- Author(s)
  衞藤義勝,　Chen Wu, 岩本武夫, 柳澤比呂子, 秋山けい子, 宮島任司, 五十嵐純子, Mohammad Arif Hossain
- Organizer
  第31回日本小児脂質研究会学術集会
- Data Source
  KAKENHI-PROJECT-17K10067
[Presentation] 乾燥濾紙血（DBS）による神経セロイドリポフスチン症（NCL）Ⅰ/Ⅱ型　新生児スクリーニングの研究2017
- Author(s)
  板垣里奈, 栁沼恵子, 遠藤昌弘, 秋山けい子, 柳澤比呂子, 岩本武夫, 新宅治夫, 衞藤義勝
- Organizer
  日本先天代謝異常学会
- Data Source
  KAKENHI-PROJECT-17K10067
[Presentation] CpG アイランドのメチル化によるFabry ヘテロ接合女性患者の臨床表現型予測について2017
- Author(s)
  Mohammad Arif Hossain, Chen Wu, 宮島任司, 柳澤比呂子, 秋山けい子, 岩本武夫, 衞藤義勝
- Organizer
  日本先天代謝異常学会　10月　川越
- Data Source
  KAKENHI-PROJECT-17K10067
[Presentation] 乾燥濾紙血（DBS）を用いたムコ多糖症Ⅶ型（MPS Ⅶ）のハイリスクスクリーニングの検討2017
- Author(s)
  宮島任司, 五十嵐純子, Chen Wu, 柳澤比呂子, Mohammad Arif Hossain,秋山けい子, 濱﨑考史, 岩本武夫, 衞藤義勝
- Organizer
  日本先天代謝異常学会
- Data Source
  KAKENHI-PROJECT-17K10067
[Presentation] An adult onset Pompe Disease with cerebral stroke and left ventricular hypertrophy.2017
- Author(s)
  Mohammad Arif Hossain, Takashi Miyajima, Keiko Akiyama, Hiroko Yanagisawa, Chen Wu, Takeo Iwamoto, Yoshikatsu Eto.
- Organizer
  第22回日本ライソゾーム病研究会
- Data Source
  KAKENHI-PROJECT-17K10067
[Presentation] 多変量解析で得た新規診断マーカー候補によるニーマンピック病C型の診断2017
- Author(s)
  Chen Wu, 岩本武夫, 柳澤比呂子, 秋山けい子, 宮島任司, 五十嵐純子, Mohammad Arif Hossain, 衞藤義勝
- Organizer
  日本先天代謝異常学会
- Data Source
  KAKENHI-PROJECT-17K10067
[Presentation] 女性ヘテロ結合ファブリー病患者におけるオートファジーとメチル化との関連2017
- Author(s)
  柳澤比呂子, ホセイン・モハンマド・アリフ, 宮島任司, 秋山けい子, 衞藤義勝
- Organizer
  日本先天代謝異常学会
- Data Source
  KAKENHI-PROJECT-17K10067
[Presentation] SPG11（Spastic Paraplegia）－著明な色素沈着を呈し Adrenoleukodystrophy（ALD）が疑われた症例2016
- Author(s)
  衞藤義勝, 板垣里奈, 柳沼恵子, 柳澤比呂子, 會田隆志, 関晴朗, 山本悌司,
- Organizer
  第58回日本先天代謝異常学会
- Place of Presentation
  東京
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-26461536
[Presentation] ロイシン添加によるオートファジー不全を改善するメカニズムとＳｐｉｎ１との関連2015
- Author(s)
  柳澤比呂子, 石井智裕, 河上江美子, 遠藤堅太郎, 平岡由佳, 上野隆, 山元大輔, 小松雅明, 渡部和彦
- Organizer
  BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会合同大会）
- Place of Presentation
  神戸ポートアイランド兵庫県　神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25460510
[Presentation] 成熟ラット後根神経節ニューロンにおけるGalectin-1ならびにGalectin-3の発現と機能2009
- Author(s)
  三五一憲, 柳澤比呂子, 小牟田縁, 堀江秀典, 門屋利彦
- Organizer
  第19回日本病態生理学会大会
- Place of Presentation
  所沢
- Year and Date
  2009-01-25
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] 成熟ラット後根神経節ニューロンにおける Galectin-1ならびに Galectin-3の発現と機能2009
- Author(s)
  三五一憲, 柳澤比呂子, 小牟田縁, 堀江秀典, 門屋利彦
- Organizer
  第19回日本病態生理学会大会
- Place of Presentation
  所沢
- Year and Date
  2009-01-25
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] Differential effects of high glucose and methylglyoxal on viability and polyol metablism in immortalized adult mouse Schwann cells.2009
- Author(s)
  Sango K, Yanagisawa H, Watabe K.
- Organizer
  Society for Neuroscience 38th Annual Meeting
- Place of Presentation
  Washington D. C. (USA)
- Year and Date
  2009-01-25
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] 神経障害モデルとしてのシュワン細胞株IMS32 : 高グルコース負荷と糖化物負荷の相違点2008
- Author(s)
  三五一憲, 柳澤比呂子, 渡部和彦
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] Differential effects of high glucose and methylglyoxal on viability and polyol metabolism in immortalized adult mouse Schwann cells2008
- Author(s)
  Sango K, Yanagisawa H, Watabe K.
- Organizer
  Society for Neuroscience 38th Annual Meeting
- Place of Presentation
  Washington D. C. (USA)
- Year and Date
  2008-11-19
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] CNTFによる後根神経節ニューロンの細胞死制御・神経突起伸長機構2008
- Author(s)
  三五一憲, 柳澤比呂子
- Organizer
  第18回日本病態生理学会大会
- Place of Presentation
  神戸
- Year and Date
  2008-01-26
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] Molecular mechanisms of pleiotrophin-induced neurite outgrowth in embryonic mouse2008
- Author(s)
  Yanagisawa H, Kawano H, Toyoda M, Maeda N, Sango K.
- Organizer
  Neuroscience 2008 (第31回日本神経科学大会)
- Place of Presentation
  東京
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] 神経障害モデルとしてのシュワン細胞株IMS32:高グルコース負荷と糖化物負荷の相違点2008
- Author(s)
  三五一憲, 柳澤比呂子, 渡部和彦
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] CNTF is a potent neuropoietic cytokine for adult rat DRG neurons.2008
- Author(s)
  Sango K, Yanagisawa H, Komuta Y, Kawano H.
- Organizer
  Neuroscience 2008(第31回日本神経科学大会)
- Place of Presentation
  東京
- Year and Date
  2008-07-09
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] CNTFによる末梢神経細胞死制御・軸索再生促進の分子機構2008
- Author(s)
  三五一憲, 柳澤比呂子, 小牟田縁, 川野仁
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] CNTF is a potent neuropoietic cytokine for adult rat DRG neurons2008
- Author(s)
  Sango K, Yanagisawa H, Komuta Y, Kawano H.
- Organizer
  Neuroscience 2008 (第31回日本神経科学大会)
- Place of Presentation
  東京
- Year and Date
  2008-07-09
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] 高グルコースならびに糖化物負荷に伴うシュワン細胞株IMS32の動態変化2008
- Author(s)
  三五一憲, 柳澤比呂子, 渡部和彦
- Organizer
  第19回日本末梢神経学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2008-09-05
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] 胎生期マウスにおけるMSpin/SPNS (Spinster homolog) の発現様式2008
- Author(s)
  柳澤比呂子, 豊田雅士, 元山純, 吉田瞳, 中野芳朗, 川野仁, 山元大輔, 三五一憲
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会)
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] 高グルコース負荷IMS32細胞におけるポリオール代謝充進と反応性アルデヒドの発現上昇2007
- Author(s)
  三五一憲、柳澤比呂子、渡部和彦
- Organizer
  第22回日本糖尿病合併症学会
- Place of Presentation
  つくば
- Year and Date
  2007-10-26
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] 培養後根神経節ニューロンを用いた、毛様体神経栄養因子の作用機構解析2007
- Author(s)
  三五一憲, 柳澤比呂子
- Organizer
  第18回末梢神経学会学術集会
- Place of Presentation
  弘前
- Year and Date
  2007-08-25
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] 培養後根神経節ニューロンを用いた、毛様体神経栄養因子の作用機構解析2007
- Author(s)
  三五一憲、柳澤比呂子
- Organizer
  第18回日本末梢神経学会学術集会
- Place of Presentation
  弘前
- Year and Date
  2007-08-25
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] 高グルコースならびに糖化物負荷IMS32細胞における酸化ストレスマーカーの発現誘導2007
- Author(s)
  三五一憲, 柳澤比呂子, 渡部和彦
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] CNTF promotes survival and neurite outgrowth of cultured adult rat dorsal root ganglion neurons.2007
- Author(s)
  Sango K, Yanagisawa H, Si Y, Kawano H.
- Organizer
  Society for Neuroscience 37th Annual Meeting
- Place of Presentation
  San Diego (USA)
- Year and Date
  2007-11-07
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] Molecular mechanisms for the neuropoietic actions of CNTF on cultured adult rat dorsal root ganglion neurons.2007
- Author(s)
  Sang K, Yanagisawa H.
- Organizer
  Neuro 2007(第30回日本神経科学大会)
- Place of Presentation
  横浜
- Year and Date
  2007-09-11
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] 高グルコース負荷IMS32細胞におけるポリオール代謝亢進と反応性アルデヒドの発現上昇2007
- Author(s)
  三五一憲, 柳澤比呂子, 渡部和彦
- Place of Presentation
  つくば
- Year and Date
  2007-10-26
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] 胎生期におけるPleiotrophin誘導神経突起伸長とwntシグナル2007
- Author(s)
  柳澤比呂子、川野仁、豊田雅士、前田信明、三五一憲
- Organizer
  BMB2007(第30回日本分子生物学会年会・第80回日本生化学会大会合同大会)
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] CNTF promotes survival and neurite outgrowth of cultured adult rat dorsal root ganglion neurons2007
- Author(s)
  Sango K, Yanagisawa H, Si Y, Kawano H.
- Organizer
  Society for Neuroscience 37th Annual Meeting
- Place of Presentation
  San Diego(USA)
- Year and Date
  2007-11-07
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] Molecular mechanisms for the neuropoietic actions of CNTF on cultured adult rat dorsal root ganglion neurons2007
- Author(s)
  Sango K., Yanagisawa H.
- Organizer
  Neuro2007(第30回日本神経科学大会)
- Place of Presentation
  横浜
- Year and Date
  2007-09-11
- Data Source
  KAKENHI-PROJECT-19500337
[Presentation] 株化ニューロン・シュワン細胞共培養系の確立とニューロパチー研究への応用
- Author(s)
  三五一憲、塚本雅美、柳澤比呂子、河上江美子、高久静香、宇都宮一典、渡部和彦
- Organizer
  第54回日本神経病理学会総会学術研究会
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-25460510
[Presentation] シュワン細胞株を用いたAmiodaroneによる末梢神経障害発症機構の解析
- Author(s)
  新見直子、柳澤比呂子、渡部和彦、三五一憲
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-25460510
[Presentation] 各種組換えウイルスベクターによるラット・マウス運動ニューロンへの遺伝子導入
- Author(s)
  渡部和彦、秋山けい子、河上江美子、石井智裕、柳澤比呂子、三五一憲、塚本雅美、岡戸晴生、三輪昭子、三宅弘一
- Organizer
  第54回日本神経病理学会総会学術研究会
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-25460510
[Presentation] L-leucine ameliorates defective autophagy through involvement of cathepsin D activation.
- Author(s)
  Hiroko Yanagisawa, DaisukeYamamoto, Emiko Kawakami, Kentaro Endo, Masaaki Komatsu, Kazuhiko Watabe
- Organizer
  9th FENS Forum of Neuroscience
- Place of Presentation
  イタリア、ミラノ MiCo - Milano Congressi
- Year and Date
  2014-07-05 – 2014-07-09
- Data Source
  KAKENHI-PROJECT-25460510
[Presentation] L-leucine添加によるオートファジー不全改善とcathepsin Dの関連
- Author(s)
  柳澤比呂子、山元大輔、河上江美子、遠藤堅太郎、小松雅明、渡部和彦
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-25460510
[Presentation] L-leucine添加によりオートファジー不全が改善するメカニズムとは？
- Author(s)
  ○ 柳澤比呂子、西藤泰昌、河上江美子、遠藤堅太郎、山元大輔、小松雅明、渡部和彦
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシイフィコ横浜(神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25460510

1. Eto Yoshikatsu (50056909)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. HOSSAIN ARIF (40777893)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
3. SANGO Kazunori (50291943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 27 results
4. KAWANO Hitoshi (20161341)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
5. WATABE Kazuhiko (30240477)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
6. KOMATSU Masaaki (90356254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. YAMAMOTO Daisuke (50318812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. 藤崎美和 (50642641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 辻嘉代子 (60584232)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. WU CHEN (90790840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
11. 衛藤義勝

# of Collaborated Projects: 0 results

# of Collaborated Products: 21 results
12. 高村歩美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YANAGISAWA Hiroko 柳澤 比呂子

Research Projects

Research Products

Co-Researchers

Pathogenesis, Diagnosis and treatment of lysosomal diseases by Biomarker Analysis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathogenetic Stidies and Novel Enzyme Treatment using Fabry, Pompe and Tay-Sacks iPS cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Does Spin1 mediate L-leucine-effects to ameliorate impaired autophagy?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms of gene regulation and action of neuroprotective factors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Dysregulated DNA methylation of GLA gene was associated with dysfunction of autophagy.2019

Author(s)

Journal Title

Data Source

[Journal Article] Future clinical and biochemical predictions of Fabry disease in females by methylation studies of the GLA gene.2019

Author(s)

Journal Title

Data Source

[Journal Article] Characteristics of PPT1 and TPP1 enzymes in neuronal ceroid lipofuscinosis (NCL) 1 and 2 by dried blood spots (DBS) and leukocytes and their application to newborn screening.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characteristics of PPT1 and TPP1 enzymes in neuronal ceroid lipofuscinosis (NCL) 1 and 2 by dried blood spots (DBS) and leukocytes and their application to newborn screening.2018

Author(s)

Journal Title

Data Source

[Journal Article] The severe clinical phenotype for a heterozygous Fabry female patient correlates to the methylation of non-mutated allele associated with chromosome 10q26 deletion syndrome.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The severe clinical phenotype for a heterozygous Fabry female patient correlates to the methylation of non-mutated allele associated with chromosome 10q26 deletion syndrome.2017

Author(s)

Journal Title

Data Source

[Journal Article] L-leucine and SPNS1 coordinately ameliorate dysfunction of autophagy in mouse and human Niemann-Pick type C disease.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Application of a diagnostic methodology by quantification of 26:0 lysophosphatidylcholine in dried blood spots for Japanese newborn screening of X-linked adrenoleukodystrophy.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ten-year-long enzyme replacement therapy shows a poor effect in alleviating giant leg ulcers in a male with Fabry disease.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Adenoviral expression of TDP-43 and FUS genes and shRNAs for protein degradation pathways in rodent motoneurons in vitro and in vivo.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differential effects of high glucose and methylglyosal on viability and polvol metabolism in immortalized adult mouse Schwann cells2008

Author(s)

Journal Title

Data Source

[Journal Article] Neuroprotective properties of ciliary neurotrophic factor for cultured adult rat dorsal root ganglion neurons.2008

Author(s)

YANAGISAWA Hiroko 柳澤比呂子

[Journal Article] Application of a diagnostic methodology by quantification of 26:0　lysophosphatidylcholine in dried blood spots for Japanese newborn screening of X-linked adrenoleukodystrophy.2017

[Presentation] 乾燥濾紙血（DBS）による神経セロイドリポフスチン症（NCL）Ⅰ/Ⅱ型　新生児スクリーニングの研究2017