DOHNO Chikara 堂野主税

… Alternative Names

堂野主税ドウノチカラ

Less

Researcher Number	60420395
Other IDs
Affiliation (Current)	2025: 大阪大学, 産業科学研究所, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 大阪大学, 産業科学研究所, 准教授 2016: 大坂大学, 産業科学研究所, 准教授 2014 – 2016: 大阪大学, 産業科学研究所, 准教授 2010 – 2011: Osaka University, 産業科学研究所, 准教授 2009 – 2010: Osaka University, 産業科学研究所, 助教 2007: Osaka University, 産業科学研究所, 助教 2006: 大阪大学, 産業科学研究所, 助手
Review Section/Research Field	Principal Investigator Basic Section 37030:Chemical biology-related / Chemistry related to living body / Biomolecular chemistry / Living organism molecular science Except Principal Investigator Chemistry / Science and Engineering / Chemical biology / Chemistry related to living body
Keywords	Principal Investigator RNA結合リガンド / DNA / 光スイッチ / 分子認識 / バイオテクノロジー / リピート病 / 相分離 / リピートRNA / ケージ化合物 / RNA高次構造 … More / RNAスイッチ / RNA分子糊 / リボザイム / リポソーム / 脂質二重膜 / 膜変形 / 両親媒性DNA / DNAナノ構造 / 有機化学 / クロスリンク / メチル化核酸塩基 / 生体認識・機能化学 / 分子糊 / ミスマッチ / RNA / ケミカルバイオロジー / ナノバイオ / ナノ材料 … More Except Principal Investigator プロープ / RNA機能調節 / 伸長抑制 / プローブ / 小分子 / 分子合成 / スクリーニング / 分子設計 / 遺伝子疾患 / 低分子 / 毒性RNA / 神経変性疾患 / 核酸結合低分子 / トリヌクレオチドリピート / インビトロセレクション / 8位置換プリン / ライブラリー / ８位置換プリン化合物 / doped library / リボスイッチ / in vivo セレクション / ８位置換プリン誘導体 / reengineering / riboswitch / chemical library / 8-substituted purine / synthesis / 機能制御 / スイッチ / 塩基対 / RNA / 光応答 / 機能化学 / 生体認識 / 機能発現 / 核酸構造 / 光異性化 / 会合体 / ヘアピンループ / 制御 / 高次構造 / 分子 / DNA / ナノテクノロジー / DNAナノ構造 / 分子認識 / ミスマッチ / 光制御 / 核酸 Less

疾患関連リピートRNAの相分離を制御するケージドリガンドの創製Principal Investigator
- Principal Investigator
  
  堂野主税
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Osaka University
RNA-based genetic switch using synthetic small molecular ligands that control RNA structure and functionPrincipal Investigator
- Principal Investigator
  
  DOHNO Chikara
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Osaka University
Transformation and recognition of shape of lipid membrane by amphiphilic DNA nanostructuresPrincipal Investigator
- Principal Investigator
  
  Dohno Chikara
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Osaka University
Chemical Biology Studies on Trinucleotide Repeat Disease using Repeat-Binding Molecules
- Principal Investigator
  
  NAKATANI Kazuhiko
- Project Period (FY)
  2014 – 2019
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Science and Engineering
  Chemistry
- Research Institution
  Osaka University
Synthesis of 8-substituted purine chemical library and riboswitch-reengineering
- Principal Investigator
  
  NAKATANI Kazuhiko
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Chemical biology
- Research Institution
  Osaka University
Photoresponsive RNA-binding ligands for regulation of RNA functionsPrincipal Investigator
- Principal Investigator
  
  DHONO Chikara
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Osaka University
Discrimination of methylated nucleobases by a novel modified DNA forming Schiff basePrincipal Investigator
- Principal Investigator
  
  DOHNO Ghikara
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Osaka University
Functional Control by Modulating the Nucleic Acid Structure Based on Mismatch Base Pair Stabilization
- Principal Investigator
  
  NAKATANI Kazuhiko
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Osaka University
光感応性ミスマッチ安定化分子の開発Principal Investigator
- Principal Investigator
  
  堂野主税
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Osaka University

[Journal Article] Photoswitchable molecular glue for RNA: reversible photocontrol of structure and function of the ribozyme2023
- Author(s)
  Chikara Dohno, Maki Kimura, Yusuke Fujiwara, Kazuhiko Nakatani
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 51 Issue: 18 Pages: 9533-9541
- DOI
  10.1093/nar/gkad690
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K23488
[Journal Article] Premature translation termination mediated non-ER stress induced ATF6 activation by a ligand-dependent ribosomal frameshifting circuit2022
- Author(s)
  Hsu Hsiu-Ting、Murata Asako、Dohno Chikara、Nakatani Kazuhiko、Chang KungYao
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 50 Issue: 9 Pages: 5369-5383
- DOI
  10.1093/nar/gkac257
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00924, KAKENHI-PROJECT-18H02107
[Journal Article] Cyclic mismatch binding ligands interact with disease-associated CGG trinucleotide repeats in RNA and suppress their translation2021
- Author(s)
  Konieczny Patryk、Mukherjee Sanjukta、Stepniak-Konieczna Ewa、Taylor Katarzyna、Niewiadomska Daria、Piasecka Agnieszka、Walczak Agnieszka、Baud Anna、Dohno Chikara、Nakatani Kazuhiko、Sobczak Krzysztof
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 49 Issue: 16 Pages: 9479-9495
- DOI
  10.1093/nar/gkab669
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00924, KAKENHI-PROJECT-18H02107
[Journal Article] Small molecule-induced trinucleotide repeat contractions during <i>in vitro</i> DNA synthesis2021
- Author(s)
  Dohno Chikara、Hagihara Masaki、Binti Mohd Zaifuddin Nursakinah、Nihei Mizuki、Saito Kaoru、Nakatani Kazuhiko
- Journal Title
  
  Chemical Communications
  
  Volume: 57 Issue: 26 Pages: 3235-3238
- DOI
  10.1039/d1cc00349f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H00924, KAKENHI-PROJECT-18H02107
[Journal Article] Short Tandem Repeat Contractions during In Vitro DNA Synthesis by Repeat-binding Molecules2021
- Author(s)
  Hagihara Masaki、Dohno Chikara、Saito Kaoru、Sugimoto Kazuhiro、Hishinuma Yuta、Sohma Yuri、Shibata Tomonori、Nakatani Kazuhiko
- Journal Title
  
  Chemistry Letters
  
  Volume: 50 Issue: 11 Pages: 1848-1851
- DOI
  10.1246/cl.210415
- NAID
  130008113718
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H00924, KAKENHI-PROJECT-18H02107, KAKENHI-PROJECT-20H02880
[Journal Article] Rational design of a photoswitchable DNA glue enabling high regulatory function and supramolecular chirality transfer2021
- Author(s)
  Simeth Nadja A.、Kobayashi Shotaro、Kobauri Piermichele、Crespi Stefano、Szymanski Wiktor、Nakatani Kazuhiko、Dohno Chikara、Feringa Ben L.
- Journal Title
  
  Chemical Science
  
  Volume: 12 Issue: 26 Pages: 9207-9220
- DOI
  10.1039/d1sc02194j
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00924, KAKENHI-PROJECT-18H02107
[Journal Article] Novel Naphthyridine Tetramer that Recognizes Tandem G-G Mismatches by Formation of Interhelical Complex2020
- Author(s)
  Lu, Y. ; Dohno, C. ; Nakatani, K.
- Journal Title
  
  Chem. Commun.
  
  Volume: 56 Issue: 5 Pages: 754-757
- DOI
  10.1039/c9cc08111a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000007, KAKENHI-PROJECT-18H02107
[Journal Article] Assembly of ruthenium complexes on double strand DNA using mismatch binding ligand2020
- Author(s)
  Ni, L. ; Yamada, T. ; Nakatani, K.
- Journal Title
  
  Chem. Commun.
  
  Volume: 56 Issue: 1 Pages: 56-61
- DOI
  10.1016/j.bbrc.2020.03.107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000007, KAKENHI-PROJECT-18H02107
[Journal Article] The dimeric form of 1, 3 - diaminoisoquinoline derivative rescued the mis - splicing of Atp2a1 and Clcn1 genes in myotonic dystrophy type 1 mouse model2020
- Author(s)
  Matsumoto, J. ; Nakamori, M. ; Okamoto, T. ; Murata, A. ; Dohno, C. ; Nakatani, K.
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 26 Issue: 63 Pages: 14305-14309
- DOI
  10.1002/chem.202001572
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26000007, KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-19K22597, KAKENHI-PROJECT-19H00924, KAKENHI-PROJECT-18H02107, KAKENHI-PROJECT-16H05321
[Journal Article] Molecular glue for RNA: Regulating RNA structure and function through a synthetic RNA binding molecule2019
- Author(s)
  Dohno, C.; Nakatani, K.
- Journal Title
  
  ChemBioChem
  
  Volume: 20 Issue: 23 Pages: 2903-2910
- DOI
  10.1002/cbic.201900223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02107, KAKENHI-PROJECT-26000007
[Journal Article] Structural insights into synthetic ligands targeting A?A pairs in disease-related CAG RNA repeats2019
- Author(s)
  Mukherjee Sanjukta、Blaszczyk Leszek、Rypniewski Wojciech、Falschlunger Christoph、Micura Ronald、Murata Asako、Dohno Chikara、Nakatani Kazuhiko、Kiliszek Agnieszka
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 47 Issue: 20 Pages: 10906-10913
- DOI
  10.1093/nar/gkz832
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-18H02107, KAKENHI-PROJECT-26000007
[Journal Article] A Dimeric 2,9‐Diamino‐1,10‐phenanthroline Derivative Improves Alternative Splicing in Myotonic Dystrophy Type 1 Cell and Mouse Models2018
- Author(s)
  Li Jinxing、Nakamori Masayuki、Matsumoto Jun、Murata Asako、Dohno Chikara、Kiliszek Agnieszka、Taylor Katarzyna、Sobczak Krzysztof、Nakatani Kazuhiko
- Journal Title
  
  Chemistry - A European Journal
  
  Volume: 24 Issue: 68 Pages: 18115-18122
- DOI
  10.1002/chem.201804368
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05355, KAKENHI-PROJECT-15K15339, KAKENHI-PROJECT-16H05321, KAKENHI-PROJECT-18H02107, KAKENHI-PROJECT-17J02038, KAKENHI-PROJECT-26000007
[Journal Article] Restoration of Ribozyme Tertiary Contact and Function by Using a Molecular Glue for RNA2018
- Author(s)
  Dohno, C. ; Kimura, M. ; Nakatani, K.
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 57 Issue: 2 Pages: 506-510
- DOI
  10.1002/anie.201709041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000007, KAKENHI-PROJECT-18H02107
[Journal Article] Amphiphilic DNA tiles for controlled insertion and 2D assembly on fluid lipid membranes: the effect on mechanical properties2017
- Author(s)
  Dohno, C.; Makishi, S.; Nakatani, K.; Contera, S
- Journal Title
  
  Nanoscale
  
  Volume: 9 Issue: 9 Pages: 3051-3058
- DOI
  10.1039/c6nr07084a
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12746, KAKENHI-PROJECT-26000007
[Journal Article] Design and synthesis of cyclic mismatch binding ligands (CMBLs) with variable linkers by ring closing metathesis and their photophysical and DNA repeat binding properties2017
- Author(s)
  Mukherjee, S. ; Dohno, C. ; Nakatani, K.
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 23 Issue: 47 Pages: 11385-11396
- DOI
  10.1002/chem.201702064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000007
[Journal Article] A Ligand that Targets CUG Trinucleotide Repeats2016
- Author(s)
  Li. J.; Matsumoto, J.; Bai, L.-P.; Murata, A.; Dohno, A.; Nakatani, K.
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 22 Issue: 42 Pages: 14881-14889
- DOI
  10.1002/chem.201602741
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01820, KAKENHI-PROJECT-26000007
[Journal Article] Synthesis of lH-pyrrolo [3,2-h] quinoline-8-amine derivatives that target CTG trinucleotide repeats2016
- Author(s)
  Matsumoto, J. ; Li, J. ; Dohno, C. ; Nakatani, K.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 11 Issue: 15 Pages: 3761-3764
- DOI
  10.1016/j.bmcl.2016.05.062
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000007
[Journal Article] Cyclic mismatch binding ligand CMBL4 binds to the 5'-T-3'/5'-GG-3' site by inducing the flipping out of thymine base2016
- Author(s)
  Mukherjee, S. ; Dohno, C. ; Asano, K. ; Nakatani, K.
- Journal Title
  
  Nucl. Acids Res.
  
  Volume: 44 Pages: 7090-7099
- DOI
  10.1093/nar/gkw672
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26000007
[Journal Article] Naphthyridine-Benzoazaquinolone : Evaluation of tricyclic system for the binding to (CAG)n Repeat DNA and RNA2016
- Author(s)
  Fukuzumi, T. ; Murata, A. ; Aikawa, H. ; Harada, Y. ; Nakatani, K.
- Journal Title
  
  Chem. Asian. J.
  
  Volume: 21 Issue: 13 Pages: 1971-1981
- DOI
  10.1002/asia.201600527
- Description
  in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007, KAKENHI-PROJECT-15K01820
[Journal Article] 2-Aminophenanthroline dimer stabilized the C-C mismatched duplex DNA2015
- Author(s)
  Li, J.; Matsumoto, J. Otabe, K.; Dohno, C.; Nakatani, K.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 23 Issue: 4 Pages: 753-758
- DOI
  10.1016/j.bmc.2014.12.062
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241073, KAKENHI-PROJECT-26000007
[Journal Article] A hybridisation-dependent membrane-insertable amphiphilic DNA2015
- Author(s)
  Dohno, C.; Matsuzaki, K.; Yamaguchi, H.; Shibata, T.; Nakatani, K.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 13 Issue: 40 Pages: 10117-10121
- DOI
  10.1039/c5ob01761k
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K12746
[Journal Article] Formation of Ligand-Assisted Complex of Two RNA Hairpin Loops2014
- Author(s)
  Changfeng Hong, Takahiro Otabe, Saki Matsumoto, Chikara Dohno, Asako Murata, Masaki Hagihara, Kazuhiko Nakatani
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 20 Issue: 18 Pages: 5244-5252
- DOI
  10.1002/chem.201304683
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J05460, KAKENHI-PROJECT-23241073, KAKENHI-PROJECT-25350958, KAKENHI-PROJECT-26000007
[Journal Article] Modulation of binding properties of amphiphilic DNA containing multiple dodecyl phosphotriester linkages to lipid bilayer membrane2014
- Author(s)
  Makishi, S.; Shibata, T.; Okazaki, M.; Dohno, C.; Nakatani, K.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 24 Issue: 15 Pages: 3578-3581
- DOI
  10.1016/j.bmcl.2014.05.042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241073, KAKENHI-PROJECT-26000007
[Journal Article] Cytosine-bulge dependent fluorescence quenching for real-time hairpin primer PCR2014
- Author(s)
  Takei, F.; Chen, X.; Yu, G.; Shibata, T.; Dohno, C.; Nakatani, K.
- Journal Title
  
  Chem. Commun.
  
  Volume: 50 Issue: 96 Pages: 15195-15198
- DOI
  10.1039/c4cc06780k
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23241073, KAKENHI-PROJECT-26000007, KAKENHI-PROJECT-24310165
[Journal Article] Ligand-induced electron spin-assembly on a DNA tile2013
- Author(s)
  H. Atsumi, S. Nakazawa, C. Dohno, K. Sato, T. Takui, K. Nakatani
- Journal Title
  
  Chemical Communications
  
  Volume: 49 Issue: 57 Pages: 6370-6372
- DOI
  10.1039/c3cc41801d
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21102004, KAKENHI-PROJECT-23241073, KAKENHI-PROJECT-23350011, KAKENHI-PROJECT-25410098
[Journal Article] G-quadruplex formation of entirely hydrophobic DNA in organic solvents2013
- Author(s)
  Shibata, T.; Dohno, C.; Nakatani, K.
- Journal Title
  
  Chem. Commun.
  
  Volume: 49 Issue: 48 Pages: 5501-5503
- DOI
  10.1039/c3cc42221f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241073
[Journal Article] Triethynylmethane: A Molecular Unit Inducing Excimer-Like Emission in Aggregated States of Hydrocarbon Fluorophores2013
- Author(s)
  Otabe, T.; Matsumoto, S.; Nakagawa, H.; Hong, C.; Dohno, C.; Nakatani, K.
- Journal Title
  
  Tetrahedron. Lett.
  
  Volume: 54 Pages: 143-146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241073
[Journal Article] A synthetic riboswitch that operates using a rationally designed ligand-RNA pair2013
- Author(s)
  Dohno, C.; Kohyama, I.; Kimura, M.; Hagihara, M.; Nakatani, K.
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 52 Issue: 38 Pages: 9976-9979
- DOI
  10.1002/anie.201303370
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23241073, KAKENHI-PROJECT-25350958
[Journal Article] Naphthyridine tetramer with a preorganized structure for 1:1 binding to a CGG/CGG sequence2012
- Author(s)
  Dohno, C.; Kohyama, I.; Hong, C; Nakatani, K.
- Journal Title
  
  Nucleic.Acids Res.
  
  Volume: 40 Issue: 6 Pages: 2771-2781
- DOI
  10.1093/nar/gkr1148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042, KAKENHI-PROJECT-24655154
[Journal Article] Assembly of a small DNA rectangular parallelepiped block into higher order nanostructures2012
- Author(s)
  Nakagawa, H.; Toda, M.; Atsumi, H.; Hagihara, M.; Hayashi-Nishino, M.; Dohno, C.; Nakatani, K.
- Journal Title
  
  Chem. Lett.
  
  Volume: 41 Pages: 1550-1552
- NAID
  10031126595
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241073
[Journal Article] Naphthyridine tetramer with a preorganized structure for 1:1 binding to a CGG/CGG sequence.2012
- Author(s)
  Dohno, C.; Kohyama, I.; Hong, C.; Nakatani, K.
- Journal Title
  
  Nucleic. Acids. Res.
  
  Volume: 40 Pages: 2771-2781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23241073
[Journal Article] Control of DNA hybridization by photoswitchable molecular glue2011
- Author(s)
  Dohno, C.; Nakatani, K.
- Journal Title
  
  Chem.Soc.Rev.
  
  Volume: 40 Issue: 12 Pages: 5718-5729
- DOI
  10.1039/c1cs15062f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042
[Journal Article] Naphthyridine tetramer with a preorganized structure for 1:1 binding to a CGG/CGG sequence2011
- Author(s)
  Dohno, C.; Kohyama, I.; Hong, C.; Nakatani, K.
- Journal Title
  
  Nucleic. Acids. Res.
  
  Volume: 40 Pages: 2771-2781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042
[Journal Article] Ligand Inducible Assembly of a DNA Tetrahedron2011
- Author(s)
  Dohno, C.; Atsumi, H.; Nakatani, K.
- Journal Title
  
  Chem. Commun.
  
  Volume: 47 Pages: 3499-3501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042
[Journal Article] Molecular-Glue-Triggered DNA Assembly To Form a Robust and Photoresponsive Nano-Network2011
- Author(s)
  Wang, C.; Pu, F.; Lin, Y.; Ren, J.; Dohno, C.; Nakatani K.; Qu, X.
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 17 Pages: 8189-8197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042
[Journal Article] Ligand Inducible Assembly of a DNA Tetrahedron2011
- Author(s)
  Dohno, C.代表, Atsumi, H.Nakatani, K.
- Journal Title
  
  Chem.Commun. 47
  
  Pages: 3499-3501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750171
[Journal Article] Ligand Inducible Assembly of a DNA Tetrahedron2011
- Author(s)
  Dohno, C., et al.
- Journal Title
  
  Chem.Commun.
  
  Volume: 47 Pages: 3499-3501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042
[Journal Article] Control of DNA hybridization by photoswitchable molecular glue2011
- Author(s)
  Dohno, C.; Nakatani, K.
- Journal Title
  
  Chem. Soc. Rev.
  
  Volume: 40 Pages: 5718-5729
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042
[Journal Article] Ligand Inducible Assembly of a DNA Tetrahedron.2011
- Author(s)
  Dohno, C.; Atsumi, H.; Nakatani, K.
- Journal Title
  
  Chem.Commun. 47
  
  Pages: 3499-3501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Molecular-Glue-Triggered DNA Assembly to Form a Robust and Photore sponsive Nano-Network2011
- Author(s)
  Wang, C.; Pu, F.; Lin, Y.; Ren, J.; Dohno, C.; Nakatani K.; Qu, X.
- Journal Title
  
  Chem.Eur.J.
  
  Volume: 17 Issue: 29 Pages: 8189-8197
- DOI
  10.1002/chem.201100194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042
[Journal Article] Ligand Inducible Assembly of a DNA Tetrahedron.2011
- Author(s)
  Dohno, C.; Atsumi, H.; Nakatani, K.
- Journal Title
  
  Chemical Communication
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Ligand Inducible Assembly of a DNA Tetrahedron2011
- Author(s)
  Dohno, C., et al.
- Journal Title
  
  Chem.Commun.
  
  Volume: 47 Pages: 3499-3501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750171
[Journal Article] Discrimination of N6-methyl Adenine in a Specific DNA Sequence2010
- Author(s)
  Dohno, C.代表, Shibata, T.Nakatani, K.
- Journal Title
  
  Chem.Commun. 46
  
  Pages: 5530-5532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750171
[Journal Article] Discrimination of N6-methyl Adenine in a Specific DNA Sequence2010
- Author(s)
  Dohno, C., et al.
- Journal Title
  
  Chem.Commun.
  
  Volume: 46 Pages: 5530-5532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042
[Journal Article] Discrimination of N6-methyl Adenine in a Specific DNA Sequence2010
- Author(s)
  Dohno, C., et al.
- Journal Title
  
  Chem.Commun.
  
  Volume: 46 Pages: 5530-5532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750171
[Journal Article] Photoswitchable Unsymmetrical Ligand for DNA Hetero-Mismatches2009
- Author(s)
  Dohno, C.; Yamamoto, T.; Nakatani, K.
- Journal Title
  
  Eur.J.Org.Chem.
  
  Pages: 4051-4058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Photoswitchable Unsymmetrical Ligand for DNA Hetero-Mismatches2009
- Author(s)
  Dohno, C.; Yamamoto, T.; Nakatani, K.
- Journal Title
  
  Eur. J. Org. Chem.
  
  Pages: 4051-4058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042
[Journal Article] The effect of linker length on binding affinity of a photoswitchable molecular glue for DNA2009
- Author(s)
  C.Dohno, et.al.
- Journal Title
  
  Bioorg.Med.Chem.
  
  Volume: 17 Pages: 2536-2543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042
[Journal Article] Photoswitchable Unsymmetrical Ligand for DNA Hetero-Mismatches2009
- Author(s)
  C.Dohno, et.al.
- Journal Title
  
  Eur.J.Org.Chem.
  
  Pages: 4051-4058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750171
[Journal Article] The effect of linker length on binding affinity of a photoswitchable molecular glue for DNA2009
- Author(s)
  C.Dohno, et.al.
- Journal Title
  
  Bioorg.Med.Chem. 17
  
  Pages: 2536-2543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21750171
[Journal Article] The Effect of Linker Length on Binding Affinity of a Photoswitchable Molecular Glue for DNA2009
- Author(s)
  Dohno, C.; Uno, S.; Sakai, S.; Oku, M.; Nakatani, K.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 17 Pages: 2536-2543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042
[Journal Article] Photoawitchable Unaymmetrical Ligand for DNA Hetero-Miamatches2009
- Author(s)
  C.Dohno, et.al.
- Journal Title
  
  Eur.J.Org.Chem.
  
  Pages: 4051-4058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] The effect of linker length on binding affinity of a photoawitchable molecular glue for DNA2009
- Author(s)
  C.Dohno, et.al.
- Journal Title
  
  Bioorg.Med.Chem. 17
  
  Pages: 2536-2543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] A Light-Driven, Supramolecular Optical Switch2009
- Author(s)
  Uno, S.; Dohno, C.; Bittermann, H.; Malinovskii, V.L.; Haner, R.; Nakatani, K.
- Journal Title
  
  Angew.Chem.Int.Ed. 48
  
  Pages: 7362-7365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] A Light-Driven, Supramolecular Optical Switch2009
- Author(s)
  Uno, S.; Dohno, C.; Bittermann, H.; Malinovskii, V. L.; Haner, R.; Nakatani, K.
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 48 Pages: 7362-7365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042
[Journal Article] Photoswitchable Unsymmetrical Ligand for DNA Hetero-Mismatches2009
- Author(s)
  C.Dohno, et.al.
- Journal Title
  
  Eur.J.Org.Chem.
  
  Pages: 4051-4058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200042
[Journal Article] Bidirectional Control of Gold Nanoparticle Assembly by Turning ON and OFF DNA hybridization with Thermally Degradable Molecular Glue for DNA2007
- Author(s)
  Peng, T., Dohno, C., Nakatani, K.
- Journal Title
  
  ChemBioChem 8
  
  Pages: 483-485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18710187
[Journal Article] Photoregulation of a Peptide-RNA Interaction on a Gold Surface2007
- Author(s)
  Hayashi, G., Hagihara, M., Dohno, C., Nakatani, K.
- Journal Title
  
  J. Am. Chem. Soc 129
  
  Pages: 8678-8679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Photoswichable Molecular Glue for DNA2007
- Author(s)
  Dohno, C., Uno, S., Nakatani, K
- Journal Title
  
  J. Am. Chem. Soc 129
  
  Pages: 11898-11899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Photoswitchable Molecular Glue for DNA2007
- Author(s)
  Dohno, C.; Uno, S.; Nakatani
- Journal Title
  
  K.J.Am.Chem.Soc. 129
  
  Pages: 11898-11899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Photoswitchable Molecular Glue for DNA2007
- Author(s)
  Dohno C.; Uno S.; Nakatani K.
- Journal Title
  
  J. Am. Chem. Soc. 129
  
  Pages: 11898-11899
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Photoregulation of a Peptide RNA Interaction on a Gold Surface2007
- Author(s)
  Hayashi G.; Hagihara M.; Dohno C.; Nakatani K.
- Journal Title
  
  J. Am. Chem. Soc. 129
  
  Pages: 8678-8679
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Photoregulation of a Peptide-RNA Interaction on a Gold Surface2007
- Author(s)
  Hayashi, G.; Hagihara, M.; Dohno, C.; Nakatani, K.
- Journal Title
  
  J.Am.Chem.Soc. 129
  
  Pages: 8678-8679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Photoswitchable Molecular Glue for DNA2007
- Author(s)
  Dohno, C., Uno, S., Nakatani, K.
- Journal Title
  
  Journal of the American Chemical Society 129
  
  Pages: 11898-11899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18710187
[Journal Article] Mismatch Binding Ligands Function as Molecular Glue of DNA2006
- Author(s)
  Peng, T., Dohno, C., Nakatani, K.
- Journal Title
  
  Angew. Chem. Int. Ed. 45
  
  Pages: 5623-5626
- Data Source
  KAKENHI-PROJECT-18710187
[Journal Article] Mismatch binding ligands function as molecular glue for DNA2006
- Author(s)
  Peng, T., Dohno, C., Nakatani,K
- Journal Title
  
  Angew.Chem.Int.Ed. 45
  
  Pages: 5623-5623
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Bidirectional Control of Gold Nanoparticle Assembly by Turning On and Off DNA Hybridization with Thermally Degradable Molecular Glue
- Author(s)
  Peng, T., Dohno, C., Nakatani, K.
- Journal Title
  
  ChemBioChem (in press)
- Data Source
  KAKENHI-PROJECT-18105006
[Journal Article] Bidirectional Control of Gold Nanoparticle Assembly by Turning ON and OFF DNA hybridization with Thermally Degradable Molecular Glue for
- Author(s)
  Peng, T., Dohno, C., Nakatani, K.
- Journal Title
  
  ChemBioChem (印刷中)
- Data Source
  KAKENHI-PROJECT-18710187
[Journal Article] Control of DNA hybridization by photoswitchable molecular glue.
- Author(s)
  Dohno, C.; Nakatani, K.
- Journal Title
  
  Chem.Soc.Rev.(総説) in press.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18105006
[Patent] DNA二本鎖形成制御2006
- Inventor(s)
  中谷和彦、Peng Tao、堂野主税
- Industrial Property Rights Holder
  大阪大学
- Industrial Property Number
  2006-162265
- Filing Date
  2006-06-12
- Data Source
  KAKENHI-PROJECT-18105006
[Presentation] 光応答性RNA結合低分子を用いたUGGAAリピートRNAの相分離体形成の光誘導とメカニズム解析2024
- Author(s)
  藤原侑亮、柴田知範、堂野主税、中谷和彦
- Organizer
  日本化学会第104春季年会
- Data Source
  KAKENHI-PROJECT-23K23488
[Presentation] Structure-Activity Relationship of RNA-binding Ligands for Control of Repeat RNA Phase Transitions2024
- Author(s)
  Yusuke Fujiwara, Tomonori Shibata, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  FISNA2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23488
[Presentation] オルト位フッ素置換アゾベンゼンを有する新規光応答性核酸分子スイッチ2023
- Author(s)
  梶原優佳、堂野主税、中谷和彦
- Organizer
  日本化学会第103春季年会
- Data Source
  KAKENHI-PROJECT-23K23488
[Presentation] RNAの形と機能を操る合成分子2023
- Author(s)
  堂野主税
- Organizer
  第1回ナノシステム研究会
- Data Source
  KAKENHI-PROJECT-23K23488
[Presentation] Temporal Control of Repeat RNA Phase Transitions Induced by Photoswitchable RNA-binding Ligands2023
- Author(s)
  Yusuke Fujiwara, Tomonori Shibata, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  ISNAC2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23488
[Presentation] Photocontrol of ribozyme structure and function by the photoresponsive RNA binder2023
- Author(s)
  Chikara Dohno, Maki Kimura, Yusuke Fujiwara, Kazuhiko Nakatani
- Organizer
  ISNAC2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23488
[Presentation] RNA反復配列を標的とした光応答性リガンドによる細胞内RNA fociの形成制御2023
- Author(s)
  藤原侑亮、柴田知範、堂野主税、中谷和彦
- Organizer
  日本化学会第103春季年会
- Data Source
  KAKENHI-PROJECT-18H02107
[Presentation] アゾベンゼン骨格をもつRNA結合分子を用いた細胞内RNA foci形成の光制御2023
- Author(s)
  藤原侑亮、柴田知範、堂野主税、中谷和彦
- Organizer
  日本ケミカルバイオロジー学会第17回年会
- Data Source
  KAKENHI-PROJECT-23K23488
[Presentation] オルト位フッ素置換アゾベンゼンを有する新規光応答性核酸分子スイッチ2023
- Author(s)
  梶原優佳、堂野主税、中谷和彦
- Organizer
  日本化学会第103春季年会
- Data Source
  KAKENHI-PROJECT-18H02107
[Presentation] RNA反復配列を標的とした光応答性リガンドによる細胞内RNA fociの形成制御2023
- Author(s)
  藤原侑亮、柴田知範、堂野主税、中谷和彦
- Organizer
  日本化学会第103春季年会
- Data Source
  KAKENHI-PROJECT-23K23488
[Presentation] Control of RNA Foci Formation by Photo-Switchable Ligands2022
- Author(s)
  Yusuke Fujiwara, Tomonori Shibata, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  ISNAC2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23488
[Presentation] Control of RNA Foci Formation by Photo-Switchable Ligands2022
- Author(s)
  Yusuke Fujiwara, Tomonori Shibata, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  ISNAC2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02107
[Presentation] 直列連結したグアニン認識部位を有する新規核酸結合リガンドの合成と評価2021
- Author(s)
  小柴佑輔、堂野主税、中谷和彦
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-18H02107
[Presentation] Photoswitching of RNA structure and function by synthetic RNA binding ligands2021
- Author(s)
  Chikara Dohno
- Organizer
  The 24th SANKEN International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02107
[Presentation] Synthetic molecular switch to regulate DNA/RNA structures and functions2020
- Author(s)
  Chikara Dohno
- Organizer
  2nd Indo-Japan (NCBS/inStem-ISIR, Osaka University) Meeting: Interfacing Chemistry and Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02107
[Presentation] 光異性化特性を向上させた新規光応答性核酸結合分子の開発2020
- Author(s)
  小林笙太朗、堂野主税、中谷和彦
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 光異性化特性を向上させた新規光応答性核酸結合分子の開発2020
- Author(s)
  小林笙太朗・堂野主税・中谷和彦
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-18H02107
[Presentation] Modulation of DNA/RNA structure and function by photoresponsive synthetic ligands2020
- Author(s)
  Chikara Dohno
- Organizer
  Osaka University - Groningen University Data Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02107
[Presentation] Regulation of RNA cleaving activity of hammerhead ribozyme by a synthetic RNA binding molecule2019
- Author(s)
  Chikara Dohno, Maki Kimura, Kazuhiko Nakatani
- Organizer
  The Commemorative International Symposium of the Japan Society of Nucleic Acids Chemistry (CISNAC 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02107
[Presentation] ピペラジン骨格を有する新規ナフチリジン誘導体の創成と RNA との結合評価2019
- Author(s)
  小林笙太朗, 廬藝歡, 堂野主税, 中谷和彦
- Organizer
  日本化学会第９９春季年会
- Data Source
  KAKENHI-PROJECT-18H02107
[Presentation] ピペラジン骨格を有する新規ナフチリジン誘導体の創成とRNAとの結合評価2019
- Author(s)
  小林笙太朗、廬藝歡、堂野主税、中谷和彦
- Organizer
  日本化学会第99春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats2019
- Author(s)
  Sanjukta Mukherjee, Leszek Blaszczyk, Wojciech Rypniewski, Christoph Falschlunger, Ronald Micura, Asako Murata, Chikara Dohno, Kazuhiko Nakatani, Agnieszka Kiliszek
- Organizer
  The 24th Annual Meeting of the RNA Society (RNA 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Modulation of ribozyme activity by conformational changes induced by a synthetic RNA binding molecule2019
- Author(s)
  Chikara Dohno, Maki Kimura, Kazuhiko Nakatani
- Organizer
  27th International Society of Heterocyclic Chemistry Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Modulation of ribozyme activity by conformational changes induced by a synthetic RNA binding molecule2019
- Author(s)
  Chikara Dohno, Maki Kimura, Kazuhiko Nakatani
- Organizer
  27th International Society of Heterocyclic Chemistry Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02107
[Presentation] Regulation of RNA cleaving activity of hammerhead ribozyme by a synthetic RNA binding molecule2019
- Author(s)
  Chikara Dohno, Maki Kimura, Kazuhiko Nakatani
- Organizer
  The Commemorative International Symposium of the Japan Society of Nucleic Acids Chemistry (CISNAC 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Targeting RNA structure and function by synthetic RNA binding ligand2019
- Author(s)
  Chikara Dohno
- Organizer
  Indo-Japan (NCBS/inStem-ISIR, Osaka University) Meeting: Interfacing Chemistry and Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02107
[Presentation] Rational design of CUG repeat binging molecule targeting Myotonic Dystrophy type 12018
- Author(s)
  Jun Matsumoto, Jinxing Li, Asako Murata, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  日本ケミカルバイオロジー学会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] RNA結合分子によるRNA高次構造と機能の制御 (Small molecules that modulate RNA structures and functions)2018
- Author(s)
  堂野主税
- Organizer
  第三回　核酸を標的とした低分子創薬研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02107
[Presentation] Development of Isoquinoline Ligand Binding to r(CUG) Repeats2018
- Author(s)
  Jun Matsumoto, Jinxing Li, Asako Murata, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  International Roundtable of Nucleosides, Nucleotides, and Nucleic Acids (IRT)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Naphthyridine tetramer as a bivalent ligand targeting DNA expanded GGGGCC sequences2018
- Author(s)
  Y. Lu, C. Dohno, K. Nakatani
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Development of Isoquinoline Ligand Binding to r(CUG) Repeats2018
- Author(s)
  Jun Matsumoto, Jinxing Li, Masayuki Nakamori, Asako Murata, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  International Symposium on Nucleic Acids Chemistry (ISNAC) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Development of Isoquinoline Ligand Binding to r(CUG) Repeats2018
- Author(s)
  Jun Matsumoto, Jinxing Li, Masayuki Nakamori, Asako Murata, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  International Symposium on Nucleic Acids Chemistry (ISNAC) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02107
[Presentation] Small molecule induced CAG/CTG repeat contraction during PCR : Repeat length dependency2018
- Author(s)
  N. Binti Mohd Zaifuddin, C. Dohno, K. Nakatani
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Rationally engineered ribozyme activatable by ligand induced restoration of tertiary structure2018
- Author(s)
  Chikara Dohno, Maki Kimura, Kazuhiko Nakatani
- Organizer
  International Symposium on Nucleic Acids Chemistry (ISNAC) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02107
[Presentation] RNA-based Genetic Switch Controlled by Synthetic RNA Binding Ligands2018
- Author(s)
  Chikara Dohno
- Organizer
  Asian 3 Roundtable on Nucleic Acids (A3RONA 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 核酸塩基認識を指向したインドール誘導体の合成及び評価2018
- Author(s)
  南凌、堂野主税、中谷和彦
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] RNA-based Genetic Switch Controlled by Synthetic RNA Binding Ligands2018
- Author(s)
  Chikara Dohno
- Organizer
  Asian 3 Roundtable on Nucleic Acids (A3RONA 2018)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02107
[Presentation] Recognition of DNA GGGGCC repeats by novel naphthyridine tetramer2018
- Author(s)
  Yihuan Lu, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  International Symposium on Nucleic Acids Chemistry (ISNAC) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02107
[Presentation] Rationally engineered ribozyme activatable by ligand induced restoration of tertiary structure2018
- Author(s)
  Chikara Dohno, Maki Kimura, Kazuhiko Nakatani
- Organizer
  International Symposium on Nucleic Acids Chemistry (ISNAC) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Recognition of DNA GGGGCC repeats by novel naphthyridine tetramer2018
- Author(s)
  Yihuan Lu, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  International Symposium on Nucleic Acids Chemistry (ISNAC) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] CAG/CTG repeat-targeting-ligands induce repeat contraction during PCR amplification2017
- Author(s)
  N. Binti Mohd Zaifuddin, C. Dohno, K. Nakatani
- Organizer
  日本ケミカルバイオロジー学会第11回年会
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Novel isoquinoline derivatives that inhibit MBNL1-CUG repeat interaction in Myotonic Dystrophy typel2017
- Author(s)
  J. Matsumoto, J. Li, A. Murata, C. Dohno, K. Nakatani
- Organizer
  ISNAC 2017 (The 44th International Symposium on Nucleic Acids Chemistry)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 疎水性官能基を有するリピートDNA結合リガンドの評価2017
- Author(s)
  山内和明、堂野主税、中谷和彦
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  慶應大学、横浜
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Synthesis and evaluation of small molecules binding to G4C2 DNA repeat2017
- Author(s)
  Yuihuan Lu, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  慶應大学、横浜
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Simple screening method for ligands affecting CAG/CTG repeats stability2017
- Author(s)
  Nursakinah Binti Mohd Zaifuddin, Jinxing Li, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  慶應大学、横浜
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] The evaluation of repeat DNA binding ligands having a hydrophobic functional group2017
- Author(s)
  山内和明・堂野主税・中谷和彦
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  慶應義塾大学（横浜市）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-15K12746
[Presentation] 疎水性官能基を有する新規DNA結合リガンドの合成2016
- Author(s)
  山内和明・堂野主税・中谷和彦
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  同志社大学京田辺キャンパス(京都府・京田辺市)
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] 疎水性官能基を有する新規DNA結合リガンドの合成2016
- Author(s)
  山内和明・堂野主税・中谷和彦
- Organizer
  日本化学会第９６春季年会
- Place of Presentation
  同志社大学京田辺キャンパス
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-15K12746
[Presentation] Binding of amphiphilic DNA to lipid membrane regulated by formation of higher order structures2016
- Author(s)
  Chikara Dohno, Hayato Yamaguchi, Shingo Makishi, Koichi Matsuzaki, Kazuhiko Nakatani
- Organizer
  ISNAC2016
- Place of Presentation
  熊本
- Year and Date
  2016-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] CAGリピートDNAおよびRNAを標的としたナフチリジンーアザキノロン誘導体の開発と転写および翻訳への阻害効果2016
- Author(s)
  阪田彬裕, 村田亜沙子, 李金星, 松本咲, Li-ping BAI, 堂野主税, 小比賀聡, 中谷和彦
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜(神奈川県・横浜市)
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Development of small molecules targeting the CUG repeats that cause myotonic dystrophy type 12016
- Author(s)
  Jinxing Li, Jun Matsumoto, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  ISNAC2016
- Place of Presentation
  熊本
- Year and Date
  2016-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Binding of amphiphilic DNA to lipid membrane regulated by formation of higher order structures2016
- Author(s)
  Chikara Dohno, Hayato Yamaguchi, Shingo Makishi, Koichi Matsuzaki, Kazuhiko Nakatani
- Organizer
  The 43rd International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  熊本大学（熊本市）
- Year and Date
  2016-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12746
[Presentation] A novel ligand that selectively targets CCG trinucIeotide repeats2015
- Author(s)
  Jinxing Li, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  ISNAC2015
- Place of Presentation
  Egret Himeji (Hyogo, Himeji)
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Analysis of binding of naphthyridine-azaquinolone derivatives to CAG repeats RNA2015
- Author(s)
  Akihiro Sakata, Jinxing Li, Hanping He, Asako Murata, Chikara Dohno, Satoshi Obika, Kazuhiko Nakatani
- Organizer
  Pacifichem2015
- Place of Presentation
  Hawaii(USA)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] CAGリピートDNAおよびRNAとナフチリジンーアザキノロン誘導体とのSPRによる結合評価2015
- Author(s)
  阪田彬裕、李金星、Hanping He、Li-ping Bai、村田亜沙子、堂野主税、小比賀聡、中谷和彦
- Organizer
  GE Life Sciences Day 2015
- Place of Presentation
  パシフィコ横浜(神奈川県・横浜市)
- Year and Date
  2015-07-24
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Binding of amphiphilic DNAs with different secondary structures to lipid bi- layer membrane2015
- Author(s)
  H. Yamaguchi, K. Matsuzaki, T. Shibata, C. Dohno, K. Nakatani
- Organizer
  Pacifichem2015
- Place of Presentation
  Honolulu, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12746
[Presentation] Evaluation of Small Molecule Ligands that Bind to GGGGCC Repeats2015
- Author(s)
  Jun Matsumoto, Saki Matsumoto, Chikara Dohno, and Kazuhiko Nakatani
- Organizer
  ISNAC2015
- Place of Presentation
  Egret Himeji (Hyogo, Himeji)
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Modulation of binding properties of DNA assemblies to lipid bilayer membrane2015
- Author(s)
  C. Dohno, S. Makishi, H. Yamaguchi, K. Nakatani
- Organizer
  Pacifichem2015
- Place of Presentation
  Honolulu, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12746
[Presentation] A novel ligand that selectively targets CUG trinucleotide repeats2015
- Author(s)
  Jinxing Li, Jun Mastumoto, Li-Ping Bai, Chikara Dohno, Zhi-Hong Jiang, and Kazuhiko Nakatani
- Organizer
  RNA2015, The 20th Annual Meeting of the RNA Society
- Place of Presentation
  Wisconsin(USA)
- Year and Date
  2015-05-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Synthesis and Binding Property of Naphthyridine-Azaquinolone Derivatives Targeting (CAG)n Repeat RNA2015
- Author(s)
  Akihiro Sakata, Jinxing Li, Hanping He, Li-ping Bai, Asako Murata, Chikara Dohno, Satoshi Obika, and Kazuhiko Nakatani
- Organizer
  ISNAC2015
- Place of Presentation
  Egret Himeji (Hyogo, Himeji)
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] CAGリピートRNAを標的としたナフチリジン-アザキノロン誘導体の機能評価2015
- Author(s)
  阪田彬裕, 村田亜沙子, 李金星, 松本咲, Li-ping BAI, 堂野主税, 小比賀聡, 中谷和彦
- Organizer
  日本核酸医薬学会第1回年会
- Place of Presentation
  京都テルサ(京都府・京都市)
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-26000007
[Presentation] Design and synthesis of RNA binding ligand for regulating gene expression2012
- Author(s)
  Chikara Dohno, Izumi Kohyama, Kazuhiko Nakatani
- Organizer
  243rd American Chemical Society National Meeting
- Place of Presentation
  San Diego (USA)
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-21200042
[Presentation] High allelic discrimination in typing of single nucleotide polymorphisms using allele-specific hairpin primer PCR2012
- Author(s)
  F. Takei, G. Yu, C. Dohno, K. Nakatani
- Organizer
  ISNAC2012
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Design and synthesis of RNA binding ligand for regulating gene expression2012
- Author(s)
  Dohno, C. (代表)
- Organizer
  243rd American Chemical Society National Meeting
- Place of Presentation
  サンディエゴ(米国)
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-21200042
[Presentation] Synthesis and application of a new modified DNA having cytosine-bulge binding fluorescent molecule2012
- Author(s)
  G. Yu, F. Takei, T. Shibata, C. Dohno, K. Nakatani
- Organizer
  ISNAC2012
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Synthesis and evaluation of hydrophobic G-quadruplex2012
- Author(s)
  T. Shibata, S. Makishi, C. Dohno, K. Nakatani
- Organizer
  ISNAC2012
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Photoswitchable molecular glue for DNA Nanotechnology2011
- Author(s)
  Chikara Dohno, 代表、招待講演
- Organizer
  International Symposium Advanced Science and Technology for Single Molecular Analysis of DNA and Related Molecules (ISSMA2011)
- Place of Presentation
  京都国際会議場(京都)
- Year and Date
  2011-01-25
- Data Source
  KAKENHI-PROJECT-21750171
[Presentation] Naphthyridine tetramer functions as a molecular glue for DNA and RNA2011
- Author(s)
  Dohno, C. (代表)
- Organizer
  第38回国際核酸化学シンポジウム
- Place of Presentation
  北海道大学(札幌)
- Year and Date
  2011-11-09
- Data Source
  KAKENHI-PROJECT-21200042
[Presentation] Photoswitchable molecular glue for DNA Nanotechnology2011
- Author(s)
  Chikara Dohno
- Organizer
  International Symposium : Advanced Science and Technology for Single Molecular Analysis of DNA and Related Molecules(ISSMA2011)
- Place of Presentation
  京都国際会議場(京都)(招待講演)
- Year and Date
  2011-01-25
- Data Source
  KAKENHI-PROJECT-21750171
[Presentation] Photoswitchable molecular glue for hybridization of nucleic acids2011
- Author(s)
  Dohno, C. (代表)
- Organizer
  XVth Symposium on Chemistry of Nucleic Acid Components
- Place of Presentation
  チェスキークルムロフ(チェコ)
- Year and Date
  2011-06-07
- Data Source
  KAKENHI-PROJECT-21200042
[Presentation] Photoswitchable molecular glue for DNA Nanotechnology2011
- Author(s)
  Dohno, C. (代表)
- Organizer
  International Symposium: Advanced Science and Technology for Single Molecular Analysis of DNA and Related Molecules (ISSMA2011)
- Place of Presentation
  京都国際会議場(京都)(招待講演)
- Year and Date
  2011-01-25
- Data Source
  KAKENHI-PROJECT-21200042
[Presentation] Photoswitchable molecular glue for DNA Nanotechnology2011
- Author(s)
  Chikara Dohno
- Organizer
  International Symposium : Advanced Science and Technology for Single Molecular Analysis of DNA and Related Molecules (ISSMA2011)
- Place of Presentation
  京都国際会議場(京都)(招待講演)
- Year and Date
  2011-01-25
- Data Source
  KAKENHI-PROJECT-21200042
[Presentation] Photoswitching of DNA hybridization by a small synthetic ligand2010
- Author(s)
  Dohno, C. (代表)
- Organizer
  The International Chemical Congress of Pacific Basin Societies (Pacifichem2010)
- Place of Presentation
  ホノルル(米国)
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-21200042
[Presentation] 光応答性分子糊を用いたDNA光スイッチングデバイス2010
- Author(s)
  堂野主税(代表)
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  近畿大学(大阪府)
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-21200042
[Presentation] Binding of tetrameric naphthyridine derivatives to DNA containing a GG-mismatch2010
- Author(s)
  Dohno, C. (代表)
- Organizer
  第37回国際核酸化学シンポジウム
- Place of Presentation
  はまぎんホール(横浜)
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-21200042
[Presentation] 核酸二次構造安定性を大きく変化させる新規光応答性小分子リガンド2009
- Author(s)
  堂野主税
- Organizer
  第24回生体機能関連化学シンポジウム
- Place of Presentation
  九州大学(福岡県)
- Year and Date
  2009-09-13
- Data Source
  KAKENHI-PROJECT-21750171
[Presentation] 核酸二次構造安定性を大きく変化させる新規光応答性小分子リガンド2009
- Author(s)
  堂野主税(代表)
- Organizer
  第24回生体機能関連化学シンポジウム
- Place of Presentation
  九州大学(福岡県)(招待講演)
- Year and Date
  2009-09-13
- Data Source
  KAKENHI-PROJECT-21200042
[Presentation] 核酸二次構造安定性を大きく変化させる新規光応答性小分子リガンド2009
- Author(s)
  堂野主税
- Organizer
  第24回生体機能関連化学シンポジウム
- Place of Presentation
  九州大学(福岡県)
- Year and Date
  2009-09-13
- Data Source
  KAKENHI-PROJECT-18105006
[Presentation] 核酸二次構造安定性を大きく変化させる新規光応答性小分子リガンド2009
- Author(s)
  堂野主税
- Organizer
  第24回生体機能関連化学シンポジウム
- Place of Presentation
  九州大学(福岡県)
- Year and Date
  2009-09-13
- Data Source
  KAKENHI-PROJECT-21200042
[Presentation] 光応答性DNA分子糊の開発2007
- Author(s)
  堂野主税、宇野真之介、中谷和彦
- Organizer
  日本ケミカルバイオロジー研究会第二回年会
- Place of Presentation
  京都大学
- Year and Date
  2007-05-09
- Data Source
  KAKENHI-PROJECT-18710187
[Presentation] 小分子リガンドによるDNA二本鎖形成の光制御2007
- Author(s)
  堂野主税、宇野真之介、中谷和彦
- Organizer
  2007年光化学討論会
- Place of Presentation
  信州大学
- Year and Date
  2007-09-28
- Data Source
  KAKENHI-PROJECT-18710187
[Presentation] Mismatch-Binding Ligands as a Molecular Glue for DNA2007
- Author(s)
  Dohno, C., Peng, T., Nakatani, K.
- Organizer
  7th International Meeting on Recognition Studies in Nucleic Acids
- Place of Presentation
  University of Sheffield
- Year and Date
  2007-04-01
- Data Source
  KAKENHI-PROJECT-18710187
[Presentation] Targeting secondary structures of pre-miRNA by small molecules : Development of potential inhibitors of pre-miRNA processing
- Author(s)
  Asako Murata, Ayako Sugai, Takeo Fukuzumi, Shiori Umemoto, Chikara Dohno, Kazuhiko Nakatani
- Organizer
  RNA 2013, the 18th Annual Meeting of the RNA Society
- Place of Presentation
  Congress Center Davos, Davos, Switzerland
- Year and Date
  2013-06-11 – 2013-06-16
- Data Source
  KAKENHI-PROJECT-23241073
[Presentation] Development of amphiphilic DNA for building of 2D nanostructure at hydrophobic-hydrophilic interface
- Author(s)
  S. Makishi, T. Shibata, C. Dohno, K. Nakatani
- Organizer
  The 5th edition of the Young Scientist Symposium by the European Institute of Chemistry and Biology (IECB)
- Place of Presentation
  ボルドー大学、フランス
- Data Source
  KAKENHI-PROJECT-23241073

1. NAKATANI Kazuhiko (70237303)

# of Collaborated Projects: 4 results

# of Collaborated Products: 103 results
2. TAKEI Fumie (30252711)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
3. HAGIHARA Masaki (40403000)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. MURATA Asako (50557121)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
5. AIKAWA Haruo (70547322)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. Nakamori Masayuki (60630233)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
7. ZHOU Daーyang (00324848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. FUKUZUMI Takeo (00592768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. YAMADA Takeshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. SHIBATA Tomonori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TAKAHASHI Masanori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. NAGAI Takeharu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 工位武治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 佐藤和信

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

DOHNO Chikara 堂野 主税

堂野 主税 ドウノ チカラ

Research Projects

Research Products

Co-Researchers

疾患関連リピートRNAの相分離を制御するケージドリガンドの創製Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

RNA-based genetic switch using synthetic small molecular ligands that control RNA structure and functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Transformation and recognition of shape of lipid membrane by amphiphilic DNA nanostructuresPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Chemical Biology Studies on Trinucleotide Repeat Disease using Repeat-Binding Molecules

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Synthesis of 8-substituted purine chemical library and riboswitch-reengineering

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Photoresponsive RNA-binding ligands for regulation of RNA functionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Discrimination of methylated nucleobases by a novel modified DNA forming Schiff basePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional Control by Modulating the Nucleic Acid Structure Based on Mismatch Base Pair Stabilization

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

光感応性ミスマッチ安定化分子の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Photoswitchable molecular glue for RNA: reversible photocontrol of structure and function of the ribozyme2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Premature translation termination mediated non-ER stress induced ATF6 activation by a ligand-dependent ribosomal frameshifting circuit2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cyclic mismatch binding ligands interact with disease-associated CGG trinucleotide repeats in RNA and suppress their translation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Small molecule-induced trinucleotide repeat contractions during <i>in vitro</i> DNA synthesis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Short Tandem Repeat Contractions during In Vitro DNA Synthesis by Repeat-binding Molecules2021

DOHNO Chikara 堂野主税

堂野主税ドウノチカラ