HARA Mutsuko 原むつ子

Researcher Number	60420832
Affiliation (based on the past Project Information) *help	2010: Juntendo University, 医学(系)研究科, 研究員 2010: 順天堂大学, 医学研究科, 研究員 2009: Juntendo University, 大学院・医学研究科, 研究員
Review Section/Research Field	Principal Investigator Dermatology
Keywords	Principal Investigator IL-31 / 皮膚炎 / マスト細胞 / Il-31 / かゆみ / アトピー性皮膚炎 / I1-31

Research Projects
(1 results)
Research Products
(10 results)

A role of mast cell-derived IL-31 in pruritus in atopic dermatitisPrincipal Investigator
- Principal Investigator
  
  HARA Mutsuko
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Juntendo University

All 2011 2010 2009

All Journal Article

[Journal Article] Circadian clock gene Period2 regulates a time-of-day-dependent variation in cutaneous anaphylactic reaction.2011
- Author(s)
  Nakamura Y, Harama D, Shimokawa N, Hara M, Suzuki R, Tahara Y, Ishimaru K, Katoh R, Okumura K, Ogawa H, Shibata S, Nakao A.
- Journal Title
  
  J Allergy Clin Immunol. 127(4)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791099
[Journal Article] Critical role of transcription factor PU.1 in the expression of CD80 and CD86 on dendritic cells.2011
- Author(s)
  Kanada S, Nishiyama C, Nakano N, Suzuki R, Maeda K, Hara M, Kitamura N, Ogawa H, Okumura K.
- Journal Title
  
  blood 117(7)
  
  Pages: 2211-2222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791099
[Journal Article] Establishment of a simple detection system for blood group ABO-specific transferase activity in DNA-transfected cells.2010
- Author(s)
  Nishida C, Nishiyama C, Satoh K, Hara M, Itoh Y, Ogawa H, Okumura K.
- Journal Title
  
  Leg Med (Tokyo) 12(4)
  
  Pages: 172-176
- NAID
  10027575992
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791099
[Journal Article] Opposite effects of Trichostatin A on activation of mast cells by different stimulants.2010
- Author(s)
  Wang QH, Nishiyama C, Nakano N, Kanada S, Hara M, Kitamura N, Shimokawa N, Lu CL, Ogawa H, Okumura K.
- Journal Title
  
  FEBS Let. 584(11)
  
  Pages: 2315-2320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791099
[Journal Article] Suppressive effects of transcription factor GATA-1 on cell type-specific gene expression in dendritic cells.2010
- Author(s)
  Shimokawa N, Nishiyama C, Nakano N, Maeda K, Suzuki R, Hara M, Fukai T, Tokura T, Miyajima H, Nakao A, Ogawa H, Okumura K.
- Journal Title
  
  62(7)
  
  Pages: 421-429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791099
[Journal Article] Antimicrobial peptides human beta-defensins and cathelicidin LL-37 induce the secretion of a pruritogenic cytokine IL-31 by human mast cells.2010
- Author(s)
  Niyonsaba F, Ushio H, Hara M, Yokoi H, Tominaga M, Takamori K, Kajiwara N, Saito H, Nagaoka I, Ogawa H, Okumura K
- Journal Title
  
  J Immunol 184(7)
  
  Pages: 3526-3534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791099
[Journal Article] Roles of PU.1 in monocyte- and mast cell-specific gene regulation : PU.1 transactivates CIITA pIV in cooperation with IFN-gamma.2009
- Author(s)
  Ito T, Nishiyama C, Nakano N, Nishiyama M, Usui Y, Takeda K, Kanada S, Fukuyama K, Akiba H, Tokura T, Hara M, Tsuboi R, Ogawa H, Okumura K.
- Journal Title
  
  Int Immunol. 21(7)
  
  Pages: 803-816
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791099
[Journal Article] FcepsilonRIalpha gene-18483A>C polymorphism affects transcriptional activity through YY1 binding.2009
- Author(s)
  Potaczek DP, Maeda K, Wang QH, Nakano N, Kanada S, Stepien E, Branicka A, Fukai T, Hara M, Tokura T, Ogawa H, Undas A, Okumura K, Nishiyama C.
- Journal Title
  
  Immunogenetics. 61(9)
  
  Pages: 649-655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791099
[Journal Article] Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA.2009
- Author(s)
  Kinoshita H, Takai T, Le TA, Kamijo S, Wang XL, Ushio H, Hara M, Kawasaki J, Vu AT, Ogawa T, Gunawan H, Ikeda S, Okumura K, Ogawa H.
- Journal Title
  
  J Allergy Clin Immunol. 123(1)
  
  Pages: 179-186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791099
[Journal Article] Involvement of PU.1 in the transcriptional regulation of TNF-alpha.2009
- Author(s)
  Fukai T, Nishiyama C, Kanada S, Nakano N, Hara M, Tokura T, Ikeda S, Ogawa H, Okumura K
- Journal Title
  
  Biochem Biophys Res Commun. 388(1)
  
  Pages: 102-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791099

HARA Mutsuko 原 むつ子

Research Projects

Research Products

A role of mast cell-derived IL-31 in pruritus in atopic dermatitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Circadian clock gene Period2 regulates a time-of-day-dependent variation in cutaneous anaphylactic reaction.2011

Author(s)

Journal Title

Data Source

[Journal Article] Critical role of transcription factor PU.1 in the expression of CD80 and CD86 on dendritic cells.2011

Author(s)

Journal Title

Data Source

[Journal Article] Establishment of a simple detection system for blood group ABO-specific transferase activity in DNA-transfected cells.2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Opposite effects of Trichostatin A on activation of mast cells by different stimulants.2010

Author(s)

Journal Title

Data Source

[Journal Article] Suppressive effects of transcription factor GATA-1 on cell type-specific gene expression in dendritic cells.2010

Author(s)

Journal Title

Data Source

[Journal Article] Antimicrobial peptides human beta-defensins and cathelicidin LL-37 induce the secretion of a pruritogenic cytokine IL-31 by human mast cells.2010

Author(s)

Journal Title

Data Source

[Journal Article] Roles of PU.1 in monocyte- and mast cell-specific gene regulation : PU.1 transactivates CIITA pIV in cooperation with IFN-gamma.2009

Author(s)

Journal Title

Data Source

[Journal Article] FcepsilonRIalpha gene-18483A>C polymorphism affects transcriptional activity through YY1 binding.2009

Author(s)

Journal Title

Data Source

[Journal Article] Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA.2009

Author(s)

Journal Title

Data Source

[Journal Article] Involvement of PU.1 in the transcriptional regulation of TNF-alpha.2009

Author(s)

Journal Title

Data Source

HARA Mutsuko 原むつ子