Yamamoto Mami 山本真実

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YAMAMOTO Mami 山本真実

田中真実タナカマミ

山本真実

田中真実(山本真実) タナカマミ

YAMAMOTO-TANAKA Mami 田中真実

山本真実ヤマモトマミ

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Researcher Number	60421062
Affiliation (Current)	2025: 東京医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2012 – 2019: 東京医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Dermatology Except Principal Investigator Dermatology
Keywords	Principal Investigator アトピー性皮膚炎 / インフラマゾーム / S100A8/A9 / カスパーゼ-14 / 不全角化 / フィラグリン / メソトリプシン / カスパーゼ‐14 / 表皮角化細胞 Except Principal Investigator 転移抑制物質 … More / Emmprin / S100A9 / 転移モデル / S100A8/A9 / S100A8/9 / 転移 / メラノーマ Less

Inflammatory mechanism associated with impaired barrier function in atopic dermatitisPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Mami
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Tokyo Medical University
The role of S100A8/A9-Emmprin in the metastasis of melanoma cells.
- Principal Investigator
  
  TSUBOI RYOJI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Tokyo Medical University
Analysis of the role of S100A8/A9 and its novel receptors in chronic inflammation in atopic dermatitisPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Mami
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Tokyo Medical University
Elucidation of the mechanism of DNA degradation during keratinocyte terminal differentiation and analysis of associated factors in diseased skin with parakeratosisPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO-TANAKA Mami
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Tokyo Medical University

All 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book

[Book] Caspase, Paracaspases, and Metacaspases2014
- Author(s)
  Yamamoto-Tanaka M, Hibino T
- Total Pages
  266
- Publisher
  Springer New York
- Data Source
  KAKENHI-PROJECT-24791180
[Book] Caspase-14 protocols. In; Methods in Molecular Biology 11332014
- Author(s)
  Yamamoto-Tanaka M, Hibino T(edited by P. Bozhov and G. Salvesen)
- Publisher
  New York : Humana Press
- Data Source
  KAKENHI-PROJECT-24791180
[Journal Article] Key component of inflammasome, NLRC4, was identified in the lesional epidermis of psoriatic patients2018
- Author(s)
  Hiruma J, Harada K, Motoyama A, Okubo Y, Maeda T, Yamamoto M, Miyai M, Hibino T, Tsuboi R
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 45 Issue: 8 Pages: 971-977
- DOI
  10.1111/1346-8138.14478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10216
[Journal Article] Neuroplastinβとextracelluar matrix metallo-protease inducerはS100A8/A9に対する機能的な受容体であり、ケラチノサイトの増殖とアトピーの皮膚炎症の増強に関与している2017
- Author(s)
  阪口政清、山本真実、宮井雅史、木下理恵、村田等、山本健一、森実真、岩月啓氏、許南浩、坪井良治、日比野利彦
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 67 Pages: 594-598
- Data Source
  KAKENHI-PROJECT-17K10216
[Journal Article] Identification of an S100A8 receptor neuroplastin-β and its heterodimer formation with EMMPRIN.2016
- Author(s)
  Sakaguchi M, Yamamoto M, Miyai M, Maeda T, Hiruma J, Murata H, Kinoshita R, Ruma IM, Putranto EW, Inoue Y, Morizane S, Huh NH, Tsuboi R, Hibino T.
- Journal Title
  
  J Invest Dermatol.
  
  Volume: 136 Issue: 11 Pages: 2240-2250
- DOI
  10.1016/j.jid.2016.06.617
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-26860899, KAKENHI-PROJECT-16K08728
[Journal Article] アトピー性皮膚炎におけるS100A8/A9と新規レセプターの役割解明2015
- Author(s)
  山本真実
- Journal Title
  
  アレルギーの臨床
  
  Volume: 35 Pages: 958-961
- Data Source
  KAKENHI-PROJECT-26860899
[Journal Article] Multiple pathways are involved in DNA degradation during keratinocyte terminal differentiation.2014
- Author(s)
  Yamamoto-Tanaka M, Makino T, Motoyama A, Miyai M, Tsuboi R, Hibino T.
- Journal Title
  
  Cell Death Dis.
  
  Volume: 5 Issue: 4 Pages: e1181-e1181
- DOI
  10.1038/cddis.2014.145
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591643, KAKENHI-PROJECT-24791180
[Journal Article] Keratinocyte-specific mesotrypsin contributes to desquamation process via kallikrein activation and LEKTI degradation.2014
- Author(s)
  Miyai M, Matsumoto Y, Yamanishi H, Yamamoto-Tanaka M, Tsuboi R, Hibino T
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: 134 Issue: 6 Pages: 1665-1674
- DOI
  10.1038/jid.2014.3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791180
[Journal Article] Keratinocyte-specific mesotrypsin contributes to desquamation process via kallikrein activation and LEKTI degradation2014
- Author(s)
  Miyai M, Matsumoto Y, Yamanishi H, Yamamoto-Tanaka M, Tsuboi R, Hibino T
- Journal Title
  
  J Invest Dermatol
  
  Volume: 134 Pages: 1665-1674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791180
[Journal Article] S100A9 is a novel ligand of EMMPRIN that promotes melanoma metastasis.2013
- Author(s)
  Hibino T, Sakaguchi M, Miyamoto S, Yamamoto M, Motoyama A, Hosoi J, Shimokata T, Ito T, Tsuboi R, Huh NH
- Journal Title
  
  Cancer Research
  
  Volume: 73 Pages: 172-183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791180
[Journal Article] Kallikrein-related peptidase 5 functions in proteolytic processing of profilaggrin in cultured human keratinocytes.2013
- Author(s)
  Sakabe JI, Yamamoto M, Hirakawa S, Motoyama A, Ohta I, Tatsuno K, Ito T, Kabashima K, Hibino T, Tokura Y
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 288 Issue: 24 Pages: 17179-17189
- DOI
  10.1074/jbc.m113.476820
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791180
[Journal Article] Kallikrein-related peptidase 5 functions in proteolytic processing of profilaggrin in cultured human keratinocytes2013
- Author(s)
  Sakabe JI, Yamamoto M, Hirakawa S, Motoyama A, Ohta I, Tatsuno K, Ito T, Kabashima K, Hibino T, Tokura Y
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Pages: 17179-17189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791180
[Journal Article] S100A9 is a novel ligand of EMMPRIN that promotes melanoma metastasis2013
- Author(s)
  Hibino T, Sakaguchi M, Miyamoto S, Yamamoto M, Motoyama A, Hosoi J, Shimokata T, Ito T, Tsuboi R, Huh NH
- Journal Title
  
  Cancer Res
  
  Volume: 73 Pages: 172-183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791180
[Journal Article] Kallikrein-related peptidase-7 regulates caspase-14 maturation during keratinocyte terminal differentiation by generating an intermediate form2012
- Author(s)
  Yamamoto M, Miyai M, Matsumoto Y, Tsuboi R, Hibino T
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Pages: 32825-32834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791180
[Journal Article] Kallikrein-related peptidase-7 regulates caspase-14 maturation during keratinocyte terminal differentiation by generating an intermediate form.2012
- Author(s)
  Yamamoto M, Miyai M, Matsumoto Y, Tsuboi R, Hibino T
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 287 Pages: 32825-32834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] The role of NLRC4, a key component of inflammasome, in the pathogenesis of psoriasis2018
- Author(s)
  Hiruma J, Harada K, Motoyama A, Okubo Y, Maeda T, Yamamoto M, Miyai M, Hibino T, Tsuboi R
- Organizer
  第32回表皮細胞研究会
- Data Source
  KAKENHI-PROJECT-17K10216
[Presentation] 乾癬における特徴的インフラマソームの同定2017
- Author(s)
  比留間淳一郎、原田和俊、大久保ゆかり、山本真実、日比野利彦、坪井良治
- Organizer
  第180回東京医科大学医学会総会
- Data Source
  KAKENHI-PROJECT-17K10216
[Presentation] 天然保湿因子（NMF）産生酵素ブレオマイシン水解酵素（BH）のバリア機能における役割2017
- Author(s)
  宮井雅史、山本真実、柴田道男、日比野利彦
- Organizer
  第35回日本美容皮膚科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-17K10216
[Presentation] 皮膚のバリア機能の研究を通じて感じたこと：臨床医が基礎研究をする意義2016
- Author(s)
  山本真実
- Organizer
  第178回東京医科大学医学会総会 100周年記念特別シンポジウム
- Place of Presentation
  東京
- Year and Date
  2016-11-05
- Invited
- Data Source
  KAKENHI-PROJECT-26860899
[Presentation] NLRC4 inflammasome is involved in the pathophysiology of psoriasis2016
- Author(s)
  Hiruma J, Miyai M, Yamamoto M, Motoyama A, Sakaguchi M, Yamanishi H, Tsuboi R, Hibino T
- Organizer
  The 75th Annual Meeting of the Society for Investigative Dermatology
- Place of Presentation
  Scottsdale, Arizona
- Year and Date
  2016-05-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860899
[Presentation] インフラマゾームの構成要素であるNOD2は乾燥状態に反応し、炎症を誘導する2016
- Author(s)
  山本真実、宮井雅史、比留間潤一郎、阪口政清、山西治代、坪井良治、日比野利彦
- Organizer
  第115回日本皮膚科学会総会
- Place of Presentation
  京都
- Year and Date
  2016-06-04
- Data Source
  KAKENHI-PROJECT-26860899
[Presentation] NOD2 inflammasome is associated with inflammatory and immune reactions in atopic dermatitis2016
- Author(s)
  Yamamoto M, Miyai M, Yamanishi H, Sakaguchi M, Hiruma J, Tsuboi R, Hibino T:
- Organizer
  The 75th Annual Meeting of the Society for Investigative Dermatology
- Place of Presentation
  Scottsdale, Arizona
- Year and Date
  2016-05-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860899
[Presentation] Epidermis-specific mesotrypsin is involved in corneocyte desquamation and is regulated by an intrinsic inhibitor, serpin B122015
- Author(s)
  Miyai M, Yamanishi H, Matsumoto Y, Yamamoto M, Hachiya Y, Tsuboi R, Hibino T
- Organizer
  The 74th Annual Meeting of the Society for Investigative Dermatology
- Place of Presentation
  Atlanta, GA
- Year and Date
  2015-05-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860899
[Presentation] 表皮特異的メソトリプシンは角層剥離を制御する - 隠された角層剥離メカニズム-2015
- Author(s)
  宮井雅史、山西治代、松元有羽子、田中（山本）真実、坪井良治、日比野利彦
- Organizer
  第38回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26860899
[Presentation] S100A9 promotes GATA3 translocation into the nucleus via EMMPRIN and down-regulates anti-inflammatory factor, NLRP102015
- Author(s)
  Hibino T, Miyai M, Sakaguchi M, Yamamoto-Tanaka M, Tsuboi R
- Organizer
  第64回日本アレルギー学会学術大会
- Place of Presentation
  東京
- Year and Date
  2015-05-27
- Data Source
  KAKENHI-PROJECT-26860899
[Presentation] Mechanism of S100A9 induction in the skin with atopic dermatitis - involvement of NOD2 inflammasome activation -2015
- Author(s)
  Yamamoto-Tanaka M, Miyai M, Sawane M, Yamanishi H, Sakaguchi M, Tsuboi R, Hibino T
- Organizer
  The 40th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  岡山
- Year and Date
  2015-12-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860899
[Presentation] NOD2 inflammasome is up-regulated in the skin with atopic dermatitis2015
- Author(s)
  Miyai M, Yamamoto-Tanaka M, Sawane M, Yamanishi H, Sakaguchi M, Tsuboi R, Hibino T
- Organizer
  The 40th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  岡山
- Year and Date
  2015-12-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860899
[Presentation] Analysis of domain structure-function relationship in NOD-like receptor family members2015
- Author(s)
  Hiruma J, Miyai M, Yamamoto-Tanaka M, Tsuboi R, Hibino T
- Organizer
  The 40th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  岡山
- Year and Date
  2015-12-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860899
[Presentation] S100A8/A9 induces skin inflammation and keratinocyte proliferation via neuroplastin-beta/EMMPRIN heterodimer receptor in atopic dermatitis2015
- Author(s)
  Miyai M, Sakaguchi M, Yamamoto-Tanaka M, Maeda T, Hiruma J, Tsuboi R, Hibino T
- Organizer
  The 45th Annual Meeting of the European Society for Dermatological Research
- Place of Presentation
  Rotterdam, The Netherlands
- Year and Date
  2015-09-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860899
[Presentation] 表皮特異的メソトリプシンは角層剥離を制御する2015
- Author(s)
  宮井雅史、山西治代、松元有羽子、松浦（八谷）有宇子、柴田道男、田中（山本）真実、坪井良治、日比野利彦
- Organizer
  第114回日本皮膚科学会総会
- Place of Presentation
  横浜
- Year and Date
  2015-05-29
- Data Source
  KAKENHI-PROJECT-26860899
[Presentation] The role of inflammasome in atopic dermatitis2015
- Author(s)
  Yamamoto-Tanaka M, Sakaguchi M, Miyai M, Hiruma J, Hibino T, Tsuboi R
- Organizer
  第29回表皮細胞研究会
- Place of Presentation
  佐賀
- Year and Date
  2015-11-14
- Data Source
  KAKENHI-PROJECT-26860899
[Presentation] S100A8 promoted Th1-related gene expression and S100A9 induced Th2 differentiation via activation of GATA-32015
- Author(s)
  Hibino T, Miyai M, Nakajima S, Yamamoto-Tanaka M, Maeda T, Sakaguchi M, Kabashima K, Tsuboi R
- Organizer
  The 45th Annual Meeting of the European Society for Dermatological Research
- Place of Presentation
  Rotterdam, The Netherlands
- Year and Date
  2015-09-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860899
[Presentation] S100A8/A9 promotes concomitant inflammation and proliferation via distinctive receptor oligomerization-potential relevance to atopic dermatitis2014
- Author(s)
  Yamamoto-Tanaka M, Sakaguchi M, Miyai M, Motoyama A, Tsuboi R, Hibino T
- Organizer
  The 73rd Annual Meeting of the Society for Investigative Dermatology
- Place of Presentation
  Albuquerque, New Mexico
- Year and Date
  2014-05-09
- Data Source
  KAKENHI-PROJECT-26860899
[Presentation] 表皮特異的メソトリプシンは角層剥離を制御する－隠された角層剥離メカニズム－2014
- Author(s)
  宮井雅史、山西治代、松元有羽子、田中(山本)真実、坪井良治、日比野利彦
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-26860899
[Presentation] Atopic dermatitis susceptible gene NALP10 suppresses inflammatory reaction and NALP10 SNP mutation down-regulates NALP10 expression2014
- Author(s)
  Miyai M, Yamamoto-Tanaka M, Inoue K, Tsuboi R, Hibino T
- Organizer
  The 39th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  大阪
- Year and Date
  2014-12-13
- Data Source
  KAKENHI-PROJECT-26860899
[Presentation] 表皮角化細胞の脱核には複数の経路が関与する－皮膚バリア機能形成における関与－2014
- Author(s)
  田中(山本)真実, 坪井良治, 日比野利彦
- Organizer
  第174回東京医科大学医学会総会
- Place of Presentation
  東京
- Year and Date
  2014-11-01
- Data Source
  KAKENHI-PROJECT-26860899
[Presentation] S100A9-EMMPRIN とinflammasome はアトピー性皮膚炎の病態に関与する2013
- Author(s)
  山本真実, 本山晃, 桃井隆, 坪井良治, 日比野利彦
- Organizer
  第112回日本皮膚科学会総会
- Place of Presentation
  横浜
- Year and Date
  2013-06-15
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] ケラチノサイト特異的メソトリプシンは、Kallikrein活性化とLEKTIの分解を介して角層剥離関与している2013
- Author(s)
  宮井雅史, 松元有羽子, 山西治代, 田中(山本)真実, 坪井良治, 日比野利彦
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] アトピー性皮膚炎におけるS100A8/A9 の役割-新規レセプターの発見とその機能2013
- Author(s)
  田中(山本)真実, 阪口政清, 本山晃, 許南浩, 日比野利彦, 坪井良治
- Organizer
  第90回東京医科大学・東京薬科大学・免疫アレルギー研究会
- Place of Presentation
  東京
- Year and Date
  2013-11-05
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] Multiple pathways are involved in DNA degradation during keratinocyte terminal differentiation2013
- Author(s)
  Yamamoto-Tanaka M, Makino T, Motoyama A, Tsuboi R, Hibino T
- Organizer
  第27回表皮細胞研究会
- Place of Presentation
  山梨
- Year and Date
  2013-11-23
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] 表皮ケラチノサイトの最終分化における脱核には複数の経路が協調的に関係している.2013
- Author(s)
  田中(山本)真実, 牧野輝彦, 本山晃, 宮井雅史, 坪井良治, 日比野利彦
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] Activation of inflammasome is related to S100A9 induction and is involved in chronic inflammation of the skin with atopic dermatitis2013
- Author(s)
  Yamamoto M, Inoue K, Sawane M, Maeda T, Tsuboi R, Hibino T
- Organizer
  International Investigative Dermatology
- Place of Presentation
  Edinburgh, Scotland
- Year and Date
  2013-05-09
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] 表皮ケラチノサイトの最終分化における脱核には複数の経路が協調的に関係している2013
- Author(s)
  田中(山本)真実, 牧野輝彦, 本山晃, 宮井雅史, 坪井良治, 日比野利彦
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2013-12-05
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] S100A9-EMMPRINとinflammasomeはアトピー性皮膚炎の病態に関与する.2013
- Author(s)
  山本真実, 本山晃, 桃井隆, 坪井良治, 日比野利彦
- Organizer
  第112回　日本皮膚科学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] Mandatory role of kallikrein 5 in profilaggrin maturation and possible association of its impairment with atopic dermatitis.2012
- Author(s)
  Sakabe J, Yamamoto M, Motoyama A, Hirakawa S, Kobayashi M, Nakamura M, Hibino T, Tokura Y
- Organizer
  The 72nd Annual Meeting of the Society for Investigative Dermatology
- Place of Presentation
  Raleigh, North Carolina
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] 表皮角化細胞の脱核のプロセスには複数の経路が関与する2012
- Author(s)
  山本真実, 牧野輝彦, 本山晃, 坪井良治, 日比野利彦
- Organizer
  第111回日本皮膚科学会総会
- Place of Presentation
  京都
- Year and Date
  2012-06-02
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] Identification of a novel receptor for S100A8 and its possible involvement in abnormal proliferation2012
- Author(s)
  Yamamoto M, Sakaguchi M, Motoyama M, Huh N, Tsuboi R, Hibino T
- Organizer
  The 37th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Okinawa, Japan
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] 表皮バリア機能関連因子プロフィラグリンのプロセッシングにおけるKLK5の関与．2012
- Author(s)
  坂部純一, 山本真実, 本山晃, 太田勲, 平川聡史, 日比野利彦, 戸倉新樹
- Organizer
  第17回日本病態プロテアーゼ学会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] Keratinocyte-specific PRSS3 participates in the desquamation process via degradation of LEKTI.2012
- Author(s)
  Miyai M, Yamanishi H, Matsumoto Y, Yamamoto M, Hibino T
- Organizer
  The 37th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Okinawa, Japan
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] KLK7 participates in activation of caspase-14 during keratinocyte terminal differentiation.2012
- Author(s)
  Yamamoto M, Miyai M, Matsumoto Y, Tsuboi R, Hibino T
- Organizer
  The 72nd Annual Meeting of the Society for Investigative Dermatology
- Place of Presentation
  Raleigh, North Carolina
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] KLK7 participates in activation of caspase-14 during keratinocyte terminal differentiation2012
- Author(s)
  Yamamoto M, Miyai M, Matsumoto Y, Tsuboi R, Hibino T
- Organizer
  The 72nd Annual Meeting of the Society for Investigative Dermatology
- Place of Presentation
  Raleigh, North Carolina
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] Analysis of profilaggrin N-terminal fragment function in keratinocyte terminal differentiation.2012
- Author(s)
  Makino T, Yamamoto M, Yamakoshi T, Rehman MU, Hibino T, Shimizu T
- Organizer
  The 72nd Annual Meeting of the Society for Investigative Dermatology
- Place of Presentation
  Raleigh, North Carolina
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] Identification of a novel receptor for S100A8 and its possible involvement in abnormal proliferation.2012
- Author(s)
  Yamamoto M, Sakaguchi M, Motoyama M, Huh NH, Tsuboi R, Hibino T
- Organizer
  The 37th Annual Meeting of the Japanese Society for Investigative Dermatology,
- Place of Presentation
  Okinawa, Japan
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] 表皮角化細胞の脱核のプロセスには複数の経路が関与する.2012
- Author(s)
  山本真実, 牧野輝彦, 本山晃, 坪井良治, 日比野利彦
- Organizer
  第111回　日本皮膚科学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] Multiple pathways are involved in DNA degradation during keratinocyte terminal differentiation.
- Author(s)
  Yamamoto-Tanaka M, Makino T, Motoyama A, Tsuboi R, Hibino T
- Organizer
  第27回表皮細胞研究会
- Place of Presentation
  山梨
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] Involvement of kallilrein-related peptidase 5 in profilaggrin processing.
- Author(s)
  Sakabe J, Yamamoto M, Motoyama A, Ohta I, Hirakawa S, Hibino T, Tokura Y
- Organizer
  International Investigative Dermatology
- Place of Presentation
  Edinburgh, Scotland
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] Keratinocyte-specific PRSS3 effectively actives KLKs and degrades LEKTI - a hidden mechanism of desquamation.
- Author(s)
  Miyai M, Matsumoto Y, Yamanishi H, Yamamoto M, Tsuboi R, Hibino T
- Organizer
  International Investigative Dermatology
- Place of Presentation
  Edinburgh, Scotland
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] Activation of inflammasome is related to S100A9 induction and is involved in chronic inflammation of the skin with atopic dermatitis.
- Author(s)
  Yamamoto M, Inoue K, Sawane M, Maeda T, Tsuboi R, Hibino T
- Organizer
  International Investigative Dermatology
- Place of Presentation
  Edinburgh, Scotland
- Data Source
  KAKENHI-PROJECT-24791180
[Presentation] アトピー性皮膚炎におけるS100A8/A9の役割－新規レセプターの発見とその機能.
- Author(s)
  田中(山本)真実, 阪口政清, 本山晃, 許南浩, 日比野利彦, 坪井良治
- Organizer
  第90回東京医科大学・東京薬科大学・免疫アレルギー研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24791180

1. TSUBOI RYOJI (70221421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. SAKAGUCHI MASAKIYO (70379840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 原田和俊 (20324197)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 前賢一郎 (60532257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MAEDA TETSUO

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. EGUSA CHIZU

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HIBINO TOSHIHIKO

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 牧野輝彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 村田等

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamamoto Mami 山本 真実

YAMAMOTO Mami 山本 真実

田中 真実 タナカ マミ

山本真実

田中 真実(山本真実) タナカ マミ

YAMAMOTO-TANAKA Mami 田中 真実

山本 真実 ヤマモト マミ

Research Projects

Research Products

Co-Researchers

Inflammatory mechanism associated with impaired barrier function in atopic dermatitisPrincipal Investigator

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The role of S100A8/A9-Emmprin in the metastasis of melanoma cells.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the role of S100A8/A9 and its novel receptors in chronic inflammation in atopic dermatitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the mechanism of DNA degradation during keratinocyte terminal differentiation and analysis of associated factors in diseased skin with parakeratosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Caspase, Paracaspases, and Metacaspases2014

Author(s)

Total Pages

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[Book] Caspase-14 protocols. In; Methods in Molecular Biology 11332014

Author(s)

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[Journal Article] Key component of inflammasome, NLRC4, was identified in the lesional epidermis of psoriatic patients2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neuroplastinβとextracelluar matrix metallo-protease inducerはS100A8/A9に対する機能的な受容体であり、ケラチノサイトの増殖とアトピーの皮膚炎症の増強に関与している2017

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[Journal Article] Identification of an S100A8 receptor neuroplastin-β and its heterodimer formation with EMMPRIN.2016

Author(s)

Journal Title

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[Journal Article] アトピー性皮膚炎におけるS100A8/A9と新規レセプターの役割解明2015

Author(s)

Journal Title

Data Source

[Journal Article] Multiple pathways are involved in DNA degradation during keratinocyte terminal differentiation.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Keratinocyte-specific mesotrypsin contributes to desquamation process via kallikrein activation and LEKTI degradation.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Keratinocyte-specific mesotrypsin contributes to desquamation process via kallikrein activation and LEKTI degradation2014

Author(s)

Journal Title

Data Source

[Journal Article] S100A9 is a novel ligand of EMMPRIN that promotes melanoma metastasis.2013

Author(s)

Journal Title

Data Source

[Journal Article] Kallikrein-related peptidase 5 functions in proteolytic processing of profilaggrin in cultured human keratinocytes.2013

Yamamoto Mami 山本真実

YAMAMOTO Mami 山本真実

田中真実タナカマミ

田中真実(山本真実) タナカマミ

YAMAMOTO-TANAKA Mami 田中真実

山本真実ヤマモトマミ