Sakaida Emiko 堺田惠美子

… Alternative Names

SAKAIDA Emiko 堺田恵美子

Less

Researcher Number	60422218
Other IDs
Affiliation (Current)	2025: 千葉大学, 大学院医学研究院, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 千葉大学, 大学院医学研究院, 准教授 2017: 千葉大学, 大学院医学研究院, 講師 2010 – 2016: 千葉大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Hematology / Respiratory organ internal medicine Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Hematology
Keywords	Principal Investigator 微小残存病変 / クローン / 次世代シークエンサー / POEMS症候群 / 形質細胞腫瘍類縁疾患 / クロウ・深瀬症候群 / 骨髄腫類縁疾患 / 形質細胞 / クロナリティ / アミロイドーシス … More / 腫瘍クローン / 形質細胞類縁疾患 / ALアミロイドーシス / 腫瘍学 / 非閉塞性肺疾患 / 呼吸器感染症 / 肺線維症 / 非閉塞性肺疾患癌 … More Except Principal Investigator POEMS症候群 / モデルマウス / 多発性骨髄腫 / 形質細胞 / シングルセル解析 / VEGF / 次世代シークエンサー / 巨核球 / 血小板 / 免疫逃避 / 成熟B細胞腫瘍 / 制御性T細胞 / 疲弊T細胞 / シングルセルRNAシークエンス / 網羅的遺伝子解析 / ALアミロイドーシス / エピジェネティック / BMI1ダウンレギュレーター / 選択的Akt阻害剤 / EZH2/EZH1共阻害剤 / ヒストンメチル化異常 / 次世代シーケンサー / POEMS syndrome / 形質細胞腫瘍 / Osteopontin / MHC class II / RNAシーケンス / 形質細胞増殖疾患 / 形質細胞増殖性疾患 / 網羅的ゲノム解析 / 骨髄微小環境 / Whole exome sequence / モノクローナル形質細胞 / RNA sequencing / Whole exome sequencing / 急性骨髄性白血病 / バイオマーカー / 血清マーカー / 血管内大細胞性B細胞型リンパ腫 / びまん性大細胞性B細胞型リンパ腫 / LR11 / 急性白血病 / 悪性リンパ腫 / 予後予測システム / 新規バイオマーカー Less

The role of megakaryocytes and platelets in pathogenesis of POEMS syndrome
- Principal Investigator
  
  塚本祥吉
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Chiba University
形質細胞シングルセルRNAシークエンスによるALアミロイドーシス網羅的遺伝子解析
- Principal Investigator
  
  竹田勇輔
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Chiba University
POEMS症候群における微小クローン同定による診断治療戦略の確立Principal Investigator
- Principal Investigator
  
  堺田惠美子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Chiba University
Elucidation of the mechanisms of immune escape in a mouse model of mature B cell neoplasms for the development of novel therapies
- Principal Investigator
  
  三村尚也
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Chiba University
Integrative epigenetic therapies using novel myeloma mouse models
- Principal Investigator
  
  Mimura Naoya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Chiba University
Elucidation of the molecular pathology of AL amyloidosis by gene expression analysis of bone marrow plasma cellsPrincipal Investigator
- Principal Investigator
  
  Sakaida Emiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Chiba University
Elucidation of the molecular mechanism of POEMS syndrome by single cell analysis of bone marrow plasma cells
- Principal Investigator
  
  Nakaseko Chiaki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  International University of Health and Welfare
Establishment of treatment strategy for POEMS syndrome based on MRD detection method with next generation sequencerPrincipal Investigator
- Principal Investigator
  
  Sakaida Emiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Chiba University
Genetic and Transcriptional Landscape of Plasma Cells in POEMS Syndrome
- Principal Investigator
  
  Nakaseko Chiaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Chiba University
An establishment of serum soluble LR11, as a novel biomarker in patients with acute leukemia and malignant lymphoma
- Principal Investigator
  
  OHWADA Chikako
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Chiba University
Analysis of individual difference of an epidermal growth factor receptor downstream signal systemPrincipal Investigator
- Principal Investigator
  
  SAKAIDA Emiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Chiba University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] UTX inactivation in germinal center B cells promotes the development of multiple myeloma with extramedullary disease2023
- Author(s)
  Rizq Ola、Mimura Naoya、Oshima Motohiko、Momose Shuji、Takayama Naoya、Itokawa Naoki、Koide Shuhei、Shibamiya Asuka、Miyamoto-Nagai Yurie、Rizk Mohamed、Nakajima-Takagi Yaeko、Aoyama Kazumasa、Wang Changshan、Saraya Atsunori、Ito Ryoji、Seimiya Masanori、et al
- Journal Title
  
  Leukemia
  
  Volume: 37 Issue: 9 Pages: 1895-1907
- DOI
  10.1038/s41375-023-01928-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07858, KAKENHI-PROJECT-22K08495, KAKENHI-PROJECT-23K05608, KAKENHI-PROJECT-23K06449, KAKENHI-PROJECT-23K07851, KAKENHI-PROJECT-20K07396, KAKENHI-PROJECT-21K08366, KAKENHI-PROJECT-22K16298, KAKENHI-PROJECT-22K16318, KAKENHI-PLANNED-19H05746, KAKENHI-PROJECT-19H05653, KAKENHI-PROJECT-23K27442
[Journal Article] The pathogenetic significance of exhausted T cells in a mouse model of mature B cell neoplasms2023
- Author(s)
  1.Shibamiya A, Miyamoto-Nagai Y, Koide S, Oshima M, Rizq O, Aoyama K, Nakajima-Takagi Y, Kato R, Kayamori K, Isshiki Y, Oshima-Hasegawa N, Muto T, Tsukamoto S, Takeda Y, Koyama-Nasu R, Chiba T, Honda H, Yokote K, Iwama A, Sakaida E, Mimura N.
- Journal Title
  
  Cancer Immunol Immunother
  
  Volume: － Issue: 8 Pages: 2635-2648
- DOI
  10.1007/s00262-023-03447-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19497, KAKENHI-PROJECT-22K08495, KAKENHI-PROJECT-23K07851, KAKENHI-PROJECT-22K16298, KAKENHI-PLANNED-19H05746, KAKENHI-PROJECT-19H05653, KAKENHI-PROJECT-23K27442
[Journal Article] Unraveling unique features of plasma cell clones in POEMS syndrome with single-cell analysis.2022
- Author(s)
  Isshiki Y, Oshima M, Mimura N, Kayamori K, Miyamoto-Nagai Y, Seki M, Nakajima-Takagi Y, Kanamori T, Iwamoto E, Muto T, Tsukamoto S, Takeda Y, Ohwada C, Misawa S, Ikeda JI, Sanada M, Kuwabara S, Suzuki Y, Sakaida E, Nakaseko C, Iwama A.
- Journal Title
  
  JCI Insight
  
  Volume: 7 Issue: 20 Pages: 1-13
- DOI
  10.1172/jci.insight.151482
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07955, KAKENHI-PROJECT-21K06881, KAKENHI-PROJECT-21K08366, KAKENHI-PROJECT-22K08447, KAKENHI-PROJECT-22K08471, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-19H05653, KAKENHI-PROJECT-20K08723, KAKENHI-PLANNED-19H05746
[Journal Article] POEMS症候群に特徴的な免疫グロブリン軽鎖変異パターン2021
- Author(s)
  一色佑介，三村尚也，塚本祥吉，堺田惠美子，中世古知昭
- Journal Title
  
  血液内科
  
  Volume: in press
- NAID
  40022600467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08338
[Journal Article] The combination of the tubulin binding small molecule PTC596 and proteasome inhibitors suppresses the growth of myeloma cells.2021
- Author(s)
  Nagai Y, Mimura N, Nakaseko C et al
- Journal Title
  
  Sci Rep
  
  Volume: 11 Issue: 1 Pages: 2074-2074
- DOI
  10.1038/s41598-021-81577-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08338, KAKENHI-PROJECT-19K08807, KAKENHI-PROJECT-20K08276, KAKENHI-PROJECT-21K19497
[Journal Article] Identification of clonal immunoglobulin λ light-chain gene rearrangements in AL amyloidosis using next-generation sequencing2021
- Author(s)
  Kimura K、Tsukamoto S、Miyazaki K、Kawajiri-Manako C、Ishii A、Rahmutulla B、Fukuyo M、Oshima-Hasegawa N、Mitsukawa S、Takeda Y、Mimura N、Takeuchi M、Ohwada C、Iseki T、Matsusaka K、Sanada M、Yokote K、Kaneda A、Ishida T、Suzuki K、Nakaseko C、Sakaida E
- Journal Title
  
  Experimental Hematology
  
  Volume: 101-102 Pages: 34-41
- DOI
  10.1016/j.exphem.2021.08.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08338, KAKENHI-PROJECT-19K07457, KAKENHI-PROJECT-19K08831, KAKENHI-PROJECT-19K16707, KAKENHI-PROJECT-20K08723
[Journal Article] Genetic subtype classification using a simplified algorithm and mutational characteristics of diffuse large B‐cell lymphoma in a Japanese cohort2021
- Author(s)
  Mishina T、Oshima‐Hasegawa N、Tsukamoto S、Fukuyo M、Kageyama H、Muto T、Mimura N、Rahmutulla B、Nagai Y、Kayamori K、Hino Y、Mitsukawa S、Takeda Y、Ohwada C、Takeuchi M、Tsujimura H、Iseki T、Nakaseko C、Ikeda J、Itami M、Yokote K、Ohara O、Kaneda A、Sakaida E
- Journal Title
  
  British Journal of Haematology
  
  Volume: 195 Issue: 5 Pages: 731-742
- DOI
  10.1111/bjh.17765
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08338, KAKENHI-PROJECT-19K16707, KAKENHI-PROJECT-21K06881
[Journal Article] Pharmacokinetically guided, once-daily intravenous busulfan in combination with fludarabine for elderly AML/MDS patients as a conditioning regimen for allogeneic stem cell transplantation2021
- Author(s)
  Ohwada C、Yamazaki S、Shono K、Kayamori K、Hino Y、Oshima-Hasegawa N、Muto T、Tsukamoto S、Mitsukawa S、Takeda Y、Mimura N、Takeuchi M、Iseki T、Onoda M、Yokota A、Suzuki T、Ishii I、Nakaseko C、Sakaida E
- Journal Title
  
  International Journal of Hematology
  
  Volume: 114 Issue: 6 Pages: 664-673
- DOI
  10.1007/s12185-021-03188-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08338
[Journal Article] Successful allogeneic bone marrow transplantation after massive gastrointestinal bleeding in a patient with myelodysplastic syndrome associated with intestinal Beh?et-like disease2021
- Author(s)
  Ishii A、Tsukamoto S、Mishina T、Izumi S、Nagai Y、Yamazaki M、Hino Y、Kayamori K、Oshima-Hasegawa N、Muto T、Mitsukawa S、Takeda Y、Mimura N、Ohwada C、Nakaseko C、Ikeda J、Sakaida E
- Journal Title
  
  Leukemia Research Reports
  
  Volume: 16 Pages: 100278-100278
- DOI
  10.1016/j.lrr.2021.100278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08338, KAKENHI-PROJECT-21K06881
[Journal Article] Genetic and transcriptional landscape of plasma cells in POEMS syndrome2019
- Author(s)
  Nagao Y, Mimura N, Takeda J, Yoshida K, Shiozawa Y, Oshima M, Aoyama K, Nishijima D, Isshiki Y, Kayamori K, Kawajiri-Manako C, Oshima-Hasegawa N, Tsukamoto S, Mitsukawa S, Takeda Y, Ohwada C, Takeuchi M, Iseki T, Misawa S, Miyano S, Ohara O, Yokote K, Sakaida E, Kuwabara S, Sanada M, Iwama A, Ogawa S, Nakaseko C.
- Journal Title
  
  Leukemia
  
  Volume: － Issue: 7 Pages: 1723-1735
- DOI
  10.1038/s41375-018-0348-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10136, KAKENHI-PROJECT-18K08338, KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-19H05656
[Journal Article] POEMS症候群の形質細胞における遺伝子異常2019
- Author(s)
  三村尚也、堺田惠美子、中世古知昭
- Journal Title
  
  腫瘍内科
  
  Volume: 24 Pages: 691-696
- NAID
  40022108670
- Data Source
  KAKENHI-PROJECT-18K08338
[Journal Article] Safety and efficacy of granulocyte-colony stimulating factor monotherapy for peripheral blood stem cell collection in POEMS Syndrome.2017
- Author(s)
  Muto T, Ohwada C, Takaishi K, Isshiki Y, Nagao Y, Hasegawa N, Kawajiri-Manako C, Togasaki E, Shimizu R, Tsukamoto S, Sakai S, Takeda Y, Mimura N, Takeuchi M, Sakaida E, Misawa S, Shimizu N, Iseki T, Kuwabara S, Nakaseko C.
- Journal Title
  
  Biol Blood Marrow Transplant
  
  Volume: 23 Issue: 2 Pages: 361-363
- DOI
  10.1016/j.bbmt.2016.10.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461397, KAKENHI-PROJECT-16K09692
[Journal Article] Acutely deteriorated extravascular volume overload during peripheral blood stem cell mobilization in POEMS syndrome: A case series with cytokine analysis.2016
- Author(s)
  Muto T, Ohwada C, Sawai S, Beppu M, Tsukamoto S, Takeda Y, Mimura N, Takeuchi M, Sakaida E, Sogawa K, Misawa S, Shimizu N, Iseki T, Nomura F, Kuwabara S, Nakaseko C.
- Journal Title
  
  Transfus Apher Sci
  
  Volume: 54 Issue: 2 Pages: 276-281
- DOI
  10.1016/j.transci.2015.10.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461397
[Journal Article] Serum soluble LR11, a novel tumor derived biomarker associated with the outcome of patients with diffuse large B-cell lymphoma.2015
- Author(s)
  Ohwada C, Yamazaki A, Kawaguchi T, Sugita Y, Takeuchi M, Shimizu N, Sakaida E, Takeda Y, Tsukamoto S, Muto T, Jiang M, Higashi M, Yokote K, Tamaru JI, Bujo H, Nakaseko C.
- Journal Title
  
  Leuk Lymphoma.
  
  Volume: 印刷中 Issue: 10 Pages: 1-4
- DOI
  10.3109/10428194.2015.1016930
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591380, KAKENHI-PROJECT-25461409, KAKENHI-PROJECT-15K15198, KAKENHI-PROJECT-15K08366, KAKENHI-PROJECT-26670362, KAKENHI-PROJECT-26293165
[Journal Article] Potential utility of serum soluble LR11 as a diagnostic biomarker for intravascular large B-cell lymphoma2014
- Author(s)
  Kawaguchi T, Ohwada C, Takeuchi M, Shimizu N, Sakaida E, Takeda Y, Sakai S, Tsukamoto S, Yamazaki A, Sugita Y, Higashi M, Fujikawa K, Matsue K, Yokote K, Tamaru JI, Bujo H, Nakaseko C
- Journal Title
  
  Leuk Lymphoma
  
  Volume: (印刷中) Issue: 10 Pages: 2391-2394
- DOI
  10.3109/10428194.2014.880430
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590413, KAKENHI-PROJECT-24591380, KAKENHI-PROJECT-25461409
[Journal Article] LR11 : a novel biomarker identified in follicular lymphoma2013
- Author(s)
  Kawaguchi T, Ohwada C, Takeuchi M, Shimizu N, Sakaida E, Takeda Y, Sakai S, Tsukamoto S, Yamazaki A, Sugita Y, Jiang M, Higashi M, Yokote K, Tamura J, Bujo H, Nakaseko C
- Journal Title
  
  Br J Haematol
  
  Volume: 163(2) Issue: 2 Pages: 277-280
- DOI
  10.1111/bjh.12467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390185, KAKENHI-PROJECT-23590413, KAKENHI-PROJECT-24390231, KAKENHI-PROJECT-24591380, KAKENHI-PROJECT-24659346, KAKENHI-PROJECT-24790907, KAKENHI-PROJECT-25461409
[Journal Article] Interaction and cross-resistance of cisplatin and pemetrexed in malignant pleural mesothelioma cell lines2012
- Author(s)
  Kitazono-Saitoh M, Takiguchi Y, Sakaida E, Sekine I, Tanabe N, et al
- Journal Title
  
  Oncology Reports
  
  Volume: 28(1) Pages: 33-40
- DOI
  10.3892/or.2012.1799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590850, KAKENHI-PROJECT-23591136, KAKENHI-PROJECT-24591185
[Journal Article] Antiproliferative action of metformin in human lung cancer cell lines2012
- Author(s)
  Ashinuma H, Takiguchi Y, Sakaida E, Sekine I, et al
- Journal Title
  
  Oncology Reports
  
  Volume: 28(1) Pages: 8-14
- DOI
  10.3892/or.2012.1763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590850, KAKENHI-PROJECT-23591136, KAKENHI-PROJECT-23689039
[Presentation] Utx欠損によるクロマチンおよびトランスクリプトームリモデリングはマウスの骨髄腫様疾患を誘発する2023
- Author(s)
  Ola Rizq,　三村尚也, 小出周平, 柴宮明日香, 宮本（長井）友莉恵, Mohamed Rizk, 大島基彦, 百瀬修二, 中島やえ子, 青山和正, 更屋敦則, 堺田惠美子, 中世古知昭, 田丸淳一, 本田浩章, 岩間厚志.
- Organizer
  第48回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08495
[Presentation] Utx loss and Braf V600E triggers myeloma-like disease in mice with increased exhausted T cells.2023
- Author(s)
  Naoya Mimura, Ola Rizq, Asuka Shibamiya, Emiko Sakaida, and Atsushi Iwama.
- Organizer
  The 13th JSH International Symposium 2023 in Tsukuba
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08495
[Presentation] 成熟B細胞腫瘍モデルマウスにおける疲弊T細胞の意義2022
- Author(s)
  柴宮明日香、三村尚也、長井友莉恵、小出周平、リズクオラ、大島基彦、青山和正、中島やえ子、栢森健介、一色佑介、大島渚、武藤朋也、塚本祥吉、竹田勇輔、岩間厚志、堺田惠美子.
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08495
[Presentation] Functional and transcriptional analyses of exhausted T cells in a mouse model of plasma cell neoplasms with human MM mutations2022
- Author(s)
  柴宮明日香 ,三村尚也 ,長井友莉恵 ,小出周平 ,リズクオラ ,大島基彦 ,栢森健介 ,一色佑介 ,日野裕太郎 ,大島渚 ,武藤朋也 ,塚本祥吉 ,竹田勇輔 ,岩間厚志 ,堺田惠美子
- Organizer
  第47回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08495
[Presentation] 次世代シークエンサーでの免疫グロブリン軽鎖遺伝子再構成の同定によるPOEMS症候群のクローン検出.2022
- Author(s)
  15.石井改、塚本祥吉、三村尚也、木村賢司、真子-川尻千華、バハテヤリラヒムトラ、福世真樹、中尾三四郎、日野裕太郎、栢森健介、大島-長谷川渚、武藤朋也、三川紫緒、竹田勇輔、水地智基、三澤園子、大和田千桂子、桑原聡史、中世古知昭、金田厚志、堺田惠美子.
- Organizer
  第84回日本血液学会学術集会.
- Data Source
  KAKENHI-PROJECT-22K08471
[Presentation] マルチパラメータフローサトメトリーによるＰＯＥＭＳ症候群のクローン性形質細胞の検出2022
- Author(s)
  石井改，塚本祥吉, 三村尚也, 長井友莉恵，一色祐介，松井愼一郎，中尾三四郎，柴宮明日香，日野祐太郎, 栢森健介, 大島渚, 武藤朋也, 三川紫緒, 竹田勇輔, 水地智基，三澤園子，大和田千桂子，横手幸太郎，桑原聡，中世古知昭, 高松博幸，堺田惠美子
- Organizer
  第47回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] マルチパラメーターフローサイトメトリーによるPOEMS症候群のクローン性形質細胞の検出2022
- Author(s)
  石井改、塚本祥吉、三村尚也、長井友莉恵、一色佑介、松井慎一郎、中尾三四郎、柴宮明日香、日野裕太郎、栢森健介、大島渚、武藤朋也、三川紫緒、竹田勇輔、水地智基、三澤園子、大和田千桂子、横手幸太郎、桑原聡、中世古知昭、高松博幸、堺田惠美子.
- Organizer
  第47回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08471
[Presentation] POEMS症候群のクローナル形質細胞に特有な遺伝子発現と表面マーカーの同定2021
- Author(s)
  一色佑介, 大島基彦, 三村尚也, 栢森健介, 長井友莉恵, 関真秀, 中島やえ子, 武藤朋也, 塚本祥吉, 竹田勇輔, 大和田千桂子, 三澤園子, 池田純一郎, 真田昌, 桑原聡, 鈴木穣, 堺田惠美子, 中世古知昭, 岩間厚志
- Organizer
  第83回日本血液学会総会
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] Utxの喪失はBrafV600E変異と協調して多発性骨髄腫様疾患を誘発する2021
- Author(s)
  Ola Rizq, 三村尚也, 小出周平, モハメドリズク, 大島基彦, 百瀬修二, 中島やえ子, 青山和正, 更屋敦則, 井関徹, 堺田惠美子, 中世古知昭, 奥野豊, 田丸淳一, 本田浩章, 岩間厚志
- Organizer
  第83回日本血液学会総会
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] 移植適応多発性骨髄腫における初回採取レジメンによる自家末梢血幹細胞採取不良例の解析2021
- Author(s)
  三村尚也, 長井友莉恵, 塚田信弘,青墳信之, 李政樹, 勝岡優奈, 若山聡雄, 鈴木利貴央, 尾崎修治, 村上博和, 中世古知昭, 堺田惠美子.
- Organizer
  日本輸血・細胞治療学会総会
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] Detection of Clonal Plasma Cells in POEMS Syndrome Using Multiparameter Flow Cytometry2021
- Author(s)
  Ishii A, Tsukamoto S, Mimura N, Nagai Y, Matsui S, Nakao S, Shibamiya A, Hino Y, Kayamori K, Oshima-Hasegawa N, Muto T, Mitsukawa S, Takeda Y, Suichi , Misawa S, Ohwada C, Yokote K, Kuwabara S, Nakaseko C, Takamatsu H, Sakaida E
- Organizer
  63rd ASH Annual Meeting and Exposition
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] 骨髄形質細胞シングルセル解析によるPOEMS症候群の分子病態の解明2021
- Author(s)
  中世古知昭, 織谷健司, 森直樹, 大和田千桂子, 渡部玲子, 東ヶ崎絵美, 桐戸敬介, 塚本祥吉, 三村尚也, 堺田恵美子
- Organizer
  国際医療福祉大学学会
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] Single plasma cell transcriptome analysis in POEMS syndrome.2020
- Author(s)
  Yusuke Isshiki, Naoya Mimura, Motohiko Oshima, Kensuke Kayamori, Masahide Seki, Kiyomi Imamura, Terumi Horiuchi, Yurie Nagai, Shokichi Tsukamoto, Yusuke Takeda, Chikako Ohwada, Sonoko Misawa, Satoshi Kuwabara, Yutaka Suzuki, Emiko Sakaida, Chiaki Nakaseko, Atsushi Iwama.
- Organizer
  25th Congress of European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] 自家移植後再燃 POEMS 症候群に対し複数回移植は有用である2020
- Author(s)
  松井慎一郎、大和田千桂子、相関祥穂、塩入勇翔、礒貝俊太郎、中尾三四郎、柴宮明日香、石井改、山﨑美貴、三科達三、長井友莉恵、日野裕太郎、木村賢司、栢森健介、大島渚、塚本祥吉、三川紫緒、竹田勇輔、三村尚也、武内正博、井関徹、中世古知昭、堺田惠美子
- Organizer
  第42回日本造血細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] ALアミロイドーシスにおけるNGSによるクローナル免疫グロブリンλ遺伝子の同定2019
- Author(s)
  木村賢司, 塚本祥吉, 堺田惠美子ら
- Organizer
  第81回日本血液学会総会
- Data Source
  KAKENHI-PROJECT-19K08831
[Presentation] NGSによるALアミロイドーシスでのクローナル免疫グロブリンλ遺伝子の同定2019
- Author(s)
  木村賢司, 塚本祥吉, 堺田惠美子ら
- Organizer
  第44回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08831
[Presentation] Identification of Clonal Immunoglobulin λ Light-Chain Gene Rearrangements in AL Amyloidosis Using Next Generation Sequencing2019
- Author(s)
  木村賢司, 塚本祥吉, 堺田惠美子ら
- Organizer
  61st ASH Annual meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08831
[Presentation] 再発POEMS症候群に対する再移植の有用性2019
- Author(s)
  柴宮明日香、大和田千桂子、松井愼一郎、中尾三四郎、石井改、長井友莉恵、三科達三、山崎美貴、一色佑介、高石浩司、木村賢司、大島渚、塚本祥吉、竹田勇輔、三川紫緒、三村尚也、武内正博、井関徹、三澤園子、桑原聡、中世古知昭、堺田惠美子
- Organizer
  第81回日本血液学会総会
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] POEMS症候群に対する自家末梢血幹細胞移植療法2018
- Author(s)
  堺田惠美子
- Organizer
  第43回日本骨髄腫学会学術集会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] POEMS症候群に対する自家末梢血幹細胞移植療法2018
- Author(s)
  堺田惠美子
- Organizer
  第43回日本骨髄腫学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-15K09494
[Presentation] POEMS症候群における形質細胞の網羅的遺伝子解析2017
- Author(s)
  永尾侑平，三村尚也，竹田淳恵，大島基彦，吉田健一，堺田惠美子, 横手幸太郎, 桑原聡，眞田昌，岩間厚志，小川誠司，中世古知昭.
- Organizer
  第54回日本臨床分子医学会学術集会
- Place of Presentation
  東京国際フォーラム(東京都)
- Year and Date
  2017-04-14
- Data Source
  KAKENHI-PROJECT-26461397
[Presentation] POEMS症候群におけるNGSを用いたλ鎖レパトア解析によるクローナルλ鎖再構成と疾患活動性の解析2017
- Author(s)
  中世古知昭，真子千華，三村尚也，福世宏枝，福世真樹，永尾侑平，大島渚，塚本祥吉，高石浩司，酒井紫緒，竹田勇輔，大和田千桂子，武内正博，井関徹，三澤園子，桑原聡，金田篤志，堺田惠美子
- Organizer
  第42回日本骨髄腫学会学術集会
- Place of Presentation
  日本赤十字看護大学(東京都)
- Year and Date
  2017-05-27
- Data Source
  KAKENHI-PROJECT-26461397
[Presentation] Clonal IGL gene rearrangements detected by NGS is correlated with disease status in POEMS syndrome2016
- Author(s)
  川尻千華, 三村尚也, 南波宏枝, 福世真樹, 永尾侑平, 東ヶ崎絵美, 清水亮, 竹田勇輔, 酒井紫緒, 大和田千桂子, 武内正博, 堺田惠美子, 井関徹, 三澤園子, 桑原聡, 築地信, 金田篤志, 中世古知昭.
- Organizer
  第78回日本血液学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26461397
[Presentation] Clonal immunoglobulin λ light-chain gene rearrangements detected by next generation sequencing in POEMS Syndrome.2016
- Author(s)
  Chika Kawajiri-Manako, Naoya Mimura, Masaki Fukuyo, Hiroe Namba-Fukuyo, Bahityar Rahmutulla, Yuhei Nagai, Yusuke Takeda, Chikako Ohwada, Masahiro Takeuchi, Emiko Sakaida, Sonoko Misawa, Koutaro Yokote, Satoshi Kuwabara, Atsushi Kaneda, Chiaki Nakaseko
- Organizer
  The 58th Annual Meeting of the American Society of Hematology
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09494
[Presentation] Distinctive genetic features of plasma cells in POEMS syndrome.2016
- Author(s)
  Nagao Y, Mimura N, Takeda J, Oshima M, Yoshida K, Shiozawa Y, Aoyama K, Saraya A, Koide S, Shiraishi Y, Chiba C, Tanaka H, Kawajiri-Manako C, Hasegawa N, Sakai S, Takeda Y, Ohwada C, Takeuchi M, Sakaida E, Iseki T, Misawa S, Yokote K, Miyano S, Ohara O, Kuwabara S, Sanada M, Iwama A, Ogawa S, Nakaseko C.
- Organizer
  The 58th Annual Meeting of the American Society of Hematology
- Place of Presentation
  San Diego Convention Center, San Diego, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461397
[Presentation] Clonal immunoglobulin λ light-chain gene rearrangements detected by next generation sequencing in POEMS Syndrome.2016
- Author(s)
  Kawajiri-Manako C, Mimura N, Fukuyo M, Namba-Fukuyo H, Rahmutulla B, Nagao Y, Togasaki E, Shimizu R, Hasegawa N, Sakai S, Takeda Y, Ohwada C, Takeuchi M, Sakaida E, Iseki T, Misawa S, Yokote K, Tsuiji M, Kuwabara S, Kaneda A, Nakaseko C.
- Organizer
  The 58th Annual Meeting of the American Society of Hematology
- Place of Presentation
  San Diego Convention Center, San Diego, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461397
[Presentation] Clonal IGL gene rearrangements detected by NGS is correlated with disease status in POEMS syndrome2016
- Author(s)
  川尻千華, 三村尚也, 南波宏枝, 福世真樹, 永尾侑平, 東ヶ崎絵美, 清水亮, 竹田勇輔, 酒井紫緒, 大和田千桂子, 武内正博, 堺田惠美子, 井関徹, 三澤園子, 桑原聡, 築地信, 金田篤志, 中世古知昭.
- Organizer
  第78回日本血液学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K09494
[Presentation] Clonal IGL gene rearrangements detected by NGS is correlated with disease status in POEMS syndrome2016
- Author(s)
  Chika Kawajiri, Naoya Mimura, Yuhei Nagao, Emi Togasaki, Ryo Shimizu, Nagisa Hasegawa, Yusuke Takeda, Shio Sakai, Chikako Ohwada, Masahiro Takeuchi, Emiko Sakaida, Tohru Iseki, Sonoko Misawa, Satoshi Kuwabara, Atsushi Kaneda, Chiaki Nakaseko
- Organizer
  第78回日本血液学会総会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26461397
[Presentation] 血清可溶型LR11（sLR11）のIntravascular large B-cell lymphoma（IVLBCL）に対する診断有用性2014
- Author(s)
  大和田千桂子、中世古知昭、川口岳晴、竹田勇輔、武内正博、堺田惠美子、清水直美、横手幸太郎
- Organizer
  第111回日本内科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25461409
[Presentation] 濾胞性リンパ腫における可溶型LR11のバイオマーカーとしての有用性2013
- Author(s)
  川口岳晴，大和田千桂子、山崎敦子、塚本祥吉、酒井紫緒、竹田勇輔、武内正博、堺田恵美子、清水直美、横手幸太郎、武城英明、中世古知昭.
- Organizer
  第50回日本臨床分子医学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25461409
[Presentation] Anti-proliferative action of metformin on various types of human lung cancer cell lines2012
- Author(s)
  Hironori Ashinuma, Yuichi Takiguchi,Satoru Kitazono, Miyako Kitazono-Saitoh, Atsushi Kitamura, Yuji Tada, Katsushi Kurosu, Emiko Sakaida, Ikuo Sekine, Nobuhiro Tanabe, Koichiro Tatsumi
- Organizer
  American Association for Cancer Research 2012 Annual Meeting
- Place of Presentation
  Chicago, IL. USA
- Data Source
  KAKENHI-PROJECT-22590850
[Presentation] Effects of metformin on a non-small cell lung cancer cell line with an EGFR mutation2012
- Author(s)
  Satoru Kitazono, Yuichi Takiguchi, Hironori Ashinuma, Miyako Kitazono, Atsushi Kitamura, Yuji Tada, Katsushi Kurosu, Emiko Sakaida, Ikuo Sekine, Koichiro Tatsumi
- Organizer
  American Association for Cancer Research 2012Annual Meeting
- Place of Presentation
  Chicago, IL. USA
- Data Source
  KAKENHI-PROJECT-22590850
[Presentation] Interaction andcross-resistance of cisplatin and pemetrexed in malignant pleural mesothelioma cell lines2012
- Author(s)
  Miyako Kitazono, Yuichi Takiguchi, Satoru Kitazono, Hironori Ashinuma, Atsushi Kitamura, Yuji Tada, Katsushi Kurosu, Emiko Sakaida, Ikuo Sekine, Nobuhiro Tanabe, Masatoshi Tagawa, Koichiro Tatsumi
- Organizer
  American Association for Cancer Research 2012 Annual Meeting
- Place of Presentation
  Chicago, IL. USA
- Data Source
  KAKENHI-PROJECT-22590850
[Presentation] The Efficacy and Long-Term Outcomes of ASCT in POEMS Syndrome: A Multicenter Retrospective Study in Japan
- Author(s)
  Chika Kawajiri, Emiko Sakaida, Chikako Ohwada, Toshihiro Miyamoto, Taichi Azuma, Jun Taguchi, Takehiko Mori, Yuichi Hasegawa, Tadakazu Kondo, Toshiaki Yujiri, Makoto Yoshimitsu, Mitsuru Tsudo, Toshihiko Iwasaki, Akio Shigematsu, Ritsuro Suzuki, Yoshiko Atsuta, Makoto Hirokawa, Hisashi Sakamaki, Chiaki Nakaseko.
- Organizer
  The 56th Annual Meeting of the American Society of Hematology
- Place of Presentation
  San Francisco
- Year and Date
  2014-12-05 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-26461397
[Presentation] 血管内大細胞性リンパ腫（IVLBCL）の診断におけるLR11の有用性
- Author(s)
  大和田千桂子、中世古知昭、川口岳晴、竹田勇輔、武内正博1、堺田恵美子、清水直美、横手幸太郎
- Organizer
  第111回日本内科学会総会
- Place of Presentation
  東京、国際フォーラム
- Year and Date
  2014-04-11 – 2014-04-13
- Data Source
  KAKENHI-PROJECT-25461409

1. Mimura Naoya (00422220)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. NAKASEKO Chiaki (30323398)

# of Collaborated Projects: 5 results

# of Collaborated Products: 30 results
3. OHWADA Chikako (80436352)

# of Collaborated Projects: 4 results

# of Collaborated Products: 16 results
4. TAKEUCHI Masahiro (50466702)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
5. 塚本祥吉 (00814617)

# of Collaborated Projects: 4 results

# of Collaborated Products: 17 results
6. 竹田勇輔 (60772746)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
7. TAKIGUCHI Yuichi (30272321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TADA Yuji (50344990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. KUROSU Katsushi (20291106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. TANABE Nobuhiro (40292700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TATSUMI Koichiro (10207061)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. BUJO Hideaki (80291300)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. MIMURA Naoya (00710229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 30 results
14. TAKIGUCHI Yuuichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
15. SANADA Masashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. SEIMIYA Masanori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 清水直美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 田辺信宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
19. 岩間厚志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 横手幸太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 東守洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 田丸淳一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 三澤園子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakaida Emiko 堺田 惠美子

SAKAIDA Emiko 堺田 恵美子

Research Projects

Research Products

Co-Researchers

The role of megakaryocytes and platelets in pathogenesis of POEMS syndrome

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

形質細胞シングルセルRNAシークエンスによるALアミロイドーシス網羅的遺伝子解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

POEMS症候群における微小クローン同定による診断治療戦略の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanisms of immune escape in a mouse model of mature B cell neoplasms for the development of novel therapies

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Integrative epigenetic therapies using novel myeloma mouse models

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the molecular pathology of AL amyloidosis by gene expression analysis of bone marrow plasma cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the molecular mechanism of POEMS syndrome by single cell analysis of bone marrow plasma cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of treatment strategy for POEMS syndrome based on MRD detection method with next generation sequencerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genetic and Transcriptional Landscape of Plasma Cells in POEMS Syndrome

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An establishment of serum soluble LR11, as a novel biomarker in patients with acute leukemia and malignant lymphoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of individual difference of an epidermal growth factor receptor downstream signal systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] UTX inactivation in germinal center B cells promotes the development of multiple myeloma with extramedullary disease2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The pathogenetic significance of exhausted T cells in a mouse model of mature B cell neoplasms2023

Author(s)

Journal Title

DOI

Sakaida Emiko 堺田惠美子

SAKAIDA Emiko 堺田恵美子