ABE TADASHI 阿部匡史

… Alternative Names

阿部匡史アベタダシ

ABE Tadashi 阿部匡史

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Researcher Number	60423282
Other IDs
Affiliation (Current)	2024: 岡山大学, 総合技術部, 技術専門員
Affiliation (based on the past Project Information) *help	2020 – 2022: 岡山大学, 医学部, 技術専門員 2016 – 2019: 岡山大学, 医学部, 技術専門職員 2010 – 2012: 岡山大学, 医学部, 技術専門職員
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Neurosurgery / Tumor biology
Keywords	Principal Investigator アクチン / ダイナミン / 浸潤 / がん / 走化 / 仮足 / 微小管 / 細胞外トラップ / SSRI / CDK5 … More / グリオーマ / 分子標的薬 / dynasore / 遊走 Less

がん細胞の浸潤転移を制御するダイナミンクロスブリッジ機構の解析Principal Investigator
- Principal Investigator
  
  阿部匡史
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Okayama University
Elucidation of the function of novel actin-binding factors in neutrophil phagocytosis and extracellular trap formationPrincipal Investigator
- Principal Investigator
  
  ABE TADASHI
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Okayama University
Development of the anti-invasive drug for treatment of malignant glioma by drug-repositioning of anti-depressant.Principal Investigator
- Principal Investigator
  
  ABE TADASHI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Okayama University
The role of dynamin in actin dynamics: Development of anticancer drugs inhibiting dynamin functionPrincipal Investigator
- Principal Investigator
  
  ABE Tadashi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Okayama University

All 2022 2021 2020 2019 2018 2017 2016 2013 2010

All Journal Article Presentation Book

[Book] Use of liposomes to study vesicular transport., Methods in Molecular Biology, 6062010
- Author(s)
  Takei K, Yamada H, Abe T.
- Data Source
  KAKENHI-PROJECT-22501013
[Journal Article] The Lipid-Binding Defective Dynamin 2 Mutant in Charcot-Marie-Tooth Disease Impairs Proper Actin Bundling and Actin Organization in Glomerular Podocytes2022
- Author(s)
  Hamasaki Eriko、Wakita Natsuki、Yasuoka Hiroki、Nagaoka Hikaru、Morita Masayuki、Takashima Eizo、Uchihashi Takayuki、Takeda Tetsuya、Abe Tadashi、Lee Ji-Won、Iimura Tadahiro、Saleem Moin A、Ogo Naohisa、Asai Akira、Narita Akihiro、Takei Kohji、Yamada Hiroshi
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 10 Pages: 884509-884509
- DOI
  10.3389/fcell.2022.884509
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06990, KAKENHI-PROJECT-22K06580, KAKENHI-PROJECT-19K10044, KAKENHI-PROJECT-20K08591
[Journal Article] Recruitment of Irgb6 to the membrane is a direct trigger for membrane deformation2022
- Author(s)
  Yamada Hiroshi、Abe Tadashi、Nagaoka Hikaru、Takashima Eizo、Nitta Ryo、Yamamoto Masahiro、Takei Kohji
- Journal Title
  
  Frontiers in Cellular and Infection Microbiology
  
  Volume: 12 Pages: 2022-2022
- DOI
  10.3389/fcimb.2022.992198
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06990, KAKENHI-PROJECT-22K06580, KAKENHI-PROJECT-21K19484, KAKENHI-PROJECT-21KK0138, KAKENHI-PROJECT-21H02724, KAKENHI-PROJECT-20K08591, KAKENHI-PROJECT-21K19352, KAKENHI-PROJECT-23K24057
[Journal Article] Mutant BIN1-Dynamin 2 complexes dysregulate membrane remodeling in the pathogenesis of centronuclear myopathy2021
- Author(s)
  Fujise K., Okubo M., Abe T., Yamada H., Nishino I., Noguchi S., Takei K., Takeda T.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 296 Pages: 100077-100077
- DOI
  10.1074/jbc.ra120.015184
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07084, KAKENHI-PROJECT-20K08591, KAKENHI-PROJECT-19H03225, KAKENHI-PROJECT-18K07198, KAKENHI-PROJECT-19KK0180
[Journal Article] Imaging‐based evaluation of pathogenicity by novel DNM2 variants associated with centronuclear myopathy2021
- Author(s)
  Fujise Kenshiro、Okubo Mariko、Abe Tadashi、Yamada Hiroshi、Takei Kohji、Nishino Ichizo、Takeda Tetsuya、Noguchi Satoru
- Journal Title
  
  Human Mutation
  
  Volume: 43 Issue: 2 Pages: 169-179
- DOI
  10.1002/humu.24307
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07084, KAKENHI-PROJECT-19H03225, KAKENHI-PROJECT-20K08591, KAKENHI-PROJECT-21K19484, KAKENHI-PROJECT-19KK0180
[Journal Article] Dynamin 1 is important for microtubule organisation and stabilisation in glomerular podocytes2020
- Author(s)
  The Mon La , Tachibana, H., Li, S.A., Abe, T., Seiriki, S., Nagaoka, H., Takashima, E., Takeda, T., Ogawa, D., Makino, S., Asanuma, K., Watanabe, M., Tian, X., Ishibe, S., Sakane, A., Sasaki, T., Wada, J., Takei, K., Yamada, H.
- Journal Title
  
  FASEB Journal
  
  Volume: 34 Issue: 12 Pages: 16449-16463
- DOI
  10.1096/fj.202001240rr
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07084, KAKENHI-PROJECT-20K08591, KAKENHI-PROJECT-19KK0180, KAKENHI-PROJECT-19H01064, KAKENHI-PROJECT-18H02651, KAKENHI-PROJECT-18H02823, KAKENHI-PROJECT-19H03225, KAKENHI-PROJECT-19H03675, KAKENHI-PROJECT-18K07198
[Journal Article] Internalization of AMPA-type glutamate receptor in the MIN6 pancreatic beta-cell line2020
- Author(s)
  The Mon La, Yamada, H., Seiriki, S., Li, S.A., Fujise, K., Katsumi, N., Abe, T., Watanabe, M., Takei, K.
- Journal Title
  
  Cell Struct. Func.
  
  Volume: 45 Issue: 2 Pages: 121-130
- DOI
  10.1247/csf.20020
- NAID
  130007889517
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07084, KAKENHI-PROJECT-20K08591
[Journal Article] Phosphorylation of cortactin by cyclin-dependent kinase 5 modulates actin bundling by the dynamin 1-cortactin ring-like complex and formation of filopodia and lamellipodia in NG108-15 glioma-derived cells2019
- Author(s)
  Tadashi Abe, The Mon La, Yuuzi Miyagaki, Eri Oya, Fan-Yan Wei, Kento Sumida, Kenshirou Fujise, Tetsuya Takeda, Kazuhito Tomizawa, Kohji Takei, Hiroshi Yamada
- Journal Title
  
  International journal of oncology
  
  Volume: 54 Pages: 550-558
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10756
[Journal Article] Dynamic clustering of dynamin-amphiphysin helices regulates membrane constriction and fission coupled with GTP hydrolysis2018
- Author(s)
  Tetsuya Takeda, Toshiya Kozai, Huiran Yang, Daiki Ishikuro, Kaho Seyama, Yusuke Kumagai, Tadashi Abe, Hiroshi Yamada, Takayuki Uchihashi, Toshio Ando, Kohji Takei
- Journal Title
  
  eLife
  
  Volume: 7 Pages: 1-19
- DOI
  10.7554/elife.30246
- NAID
  120006510224
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10756, KAKENHI-PUBLICLY-16H00758, KAKENHI-PUBLICLY-16H00830, KAKENHI-PLANNED-26119003, KAKENHI-PROJECT-17H06121, KAKENHI-PROJECT-15H03540, KAKENHI-PROJECT-15K15330, KAKENHI-PROJECT-17K08808
[Journal Article] Dynamin2 GTPase contributes to invadopodia formation in invasive bladder cancer cells.2016
- Author(s)
  Zhang, Y., Nolan, M., Yamada, H., Watanabe, M., Nasu, Y., Takei, K., Takeda, T.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 480 Issue: 3 Pages: 409-414
- DOI
  10.1016/j.bbrc.2016.10.063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10756, KAKENHI-PROJECT-15K15330, KAKENHI-PROJECT-26670201
[Journal Article] Actin bundling by dynamin 2 and cortactin is implicated in cell migration by stabilizing filopodia in human non-small cell lung carcinoma cells.2016
- Author(s)
  Yamada H, Takeda T, Michiue H, Abe T, Takei K.
- Journal Title
  
  Int J Oncol.
  
  Volume: 49(3） Issue: 3 Pages: 877-86
- DOI
  10.3892/ijo.2016.3592
- NAID
  120006352349
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10333, KAKENHI-PROJECT-16K10756, KAKENHI-PROJECT-15K15330, KAKENHI-PROJECT-26670201
[Journal Article] Stabilization of actin bundles by a Dynamin 12013
- Author(s)
  Yamada H, Abe T
- Journal Title
  
  Cortactin ring complex is necessary for growth cone filopodia.
  
  Volume: 33 Issue: 10 Pages: 4514-4526
- DOI
  10.1523/jneurosci.2762-12.2013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501013, KAKENHI-PROJECT-22616004, KAKENHI-PROJECT-23370089, KAKENHI-PROJECT-23570167, KAKENHI-PROJECT-23659213
[Presentation] 1.脂質膜結合活性が低下しているダイナミン２のCMT変異体は、ポドサイトにおけるアクチン線維の配向とアクチンバンドル形成を異常にする2022
- Author(s)
  山田浩司、阿部匡史、内橋貴之、成田哲博、竹田哲也、竹居孝二
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K06580
[Presentation] ダイナミン1は微小管の配向を調節しTRPV2の細胞膜移行を制御する2021
- Author(s)
  籔彩夏, 安岡宏樹, 片野坂友紀, 阿部匡史, 竹田哲也, 竹居孝二, 山田浩司
- Organizer
  第62回日本生化学会中国・四国支部例会
- Data Source
  KAKENHI-PROJECT-19K07084
[Presentation] ダイナミン2の自己重合と膜との相互作用は糸球体ポドサイトのアクチン制御に重要である2021
- Author(s)
  濱崎英理子, 安岡宏樹, 和木田夏輝, 阿部匡史, 竹田哲也, 竹居孝二, 山田浩司
- Organizer
  第62回日本生化学会中国・四国支部例会
- Data Source
  KAKENHI-PROJECT-19K07084
[Presentation] 糸球体ポドサイトからのグルタミン酸の放出と開口放出関連タンパクの探索2021
- Author(s)
  安岡宏樹, 西井尚子, 原田結加, 宮地孝明, 阿部匡史, 竹田哲也, 和田淳, 竹居孝二, 山田浩司
- Organizer
  第62回日本生化学会中国・四国支部例会
- Data Source
  KAKENHI-PROJECT-19K07084
[Presentation] ダイナミン GTP アーゼはアクチン線維の束化と分散を機械的に制御する2019
- Author(s)
  竹居孝二 , テモンラ, 阿部匡史, 竹田哲也, 藤原郁子, 成田哲博
- Organizer
  第57回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19K07084
[Presentation] 腎糸球体ポドサイトにおけるアンフィファイジン１の機能2019
- Author(s)
  山田浩司, The Mon La, 竹田哲也, 阿部匡史, 淺沼克彦, 竹居孝二
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07084
[Presentation] Amphiphysin 1 is important for actin cytoskeletal regulation with synaptopodin in glomerular podocytes2019
- Author(s)
  The Mon La, Tadashi Abe, Masayuki Morita, Eizo Takashima, Tetsuya Takeda, Katsuhiko Asanuma, Takei Kohji, Hiroshi Yamada
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07084
[Presentation] 腎糸球体ポドサイトにおけるダイナミンイソフォームの局在と機能2019
- Author(s)
  阿部匡史, The Mon La, 橘　洋美, 竹田哲也, 竹居孝二, 山田浩司
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07084
[Presentation] ダイナミン2のシャルコー・マリー・トゥース病の原因変異とアクチン再構成との相関2018
- Author(s)
  隅田健斗, The Mon La, 和木田夏輝, 森田将之, 高島英造, 竹田哲也, 阿部匡史, 竹居孝二, 山田浩司
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K10756
[Presentation] メカノエンザイム・ダイナミンGTPaseによるアクチン線維束化機構の解析2018
- Author(s)
  山田浩司, 阿部匡史, 竹田哲也, 高島英造, 森田将之, 竹居孝二
- Organizer
  第70回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-16K10756
[Presentation] Role of amphiphysin 1 in actin regulation of glomerular podocyte2018
- Author(s)
  The Mon La, Wakita N, Sumida K, Takeda T, Abe T, Takei K, Yamada H
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K10756
[Presentation] アンフィファイジン１の腎糸球体ポドサイトにおける役割2017
- Author(s)
  The Mon La, Natsuki Wakita, Kento Sumida, Tetsuya Takeda, Tadashi Abe, Kohji Takei, Hiroshi Yamada
- Organizer
  2017年度生命科学系学会合同年次大会　ConBio2017
- Data Source
  KAKENHI-PROJECT-16K10756
[Presentation] “Clusterase” model of dynamin-mediated membrane fission.2017
- Author(s)
  T. Takeda , T. Kozai , H. Yang , K. Seyama, Y. Kumagai, T. Abe, H. Yamada, T. Uchihashi, T. Ando, K. Takei
- Organizer
  The 2017 ASCB / EMBO Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10756
[Presentation] ダイナミン2のシャルコー・マリー・トゥース病の原因変異は腎ポドサイトのアクチン再構成を阻害する2017
- Author(s)
  和木田夏輝、The Mon La、隅田健斗、竹田哲也、阿部匡史、竹居孝二、山田浩司
- Organizer
  2017年度生命科学系学会合同年次大会　ConBio2017
- Data Source
  KAKENHI-PROJECT-16K10756
[Presentation] ダイナミン-コルタクチンらせん状複合体の解析：機械的なアクチン線維束形成とアクチン脱重合保護作用2017
- Author(s)
  阿部匡史、山田浩司、竹田哲也、内橋貴之、安藤敏夫、竹居孝二
- Organizer
  2017年度生命科学系学会合同年次大会　ConBio2017
- Data Source
  KAKENHI-PROJECT-16K10756
[Presentation] ダイナミンによる膜切断過程の動態イメージング2017
- Author(s)
  竹田哲也、小財稔矢、楊恵然、石黒大輝、背山佳穂、熊谷祐介、阿部匡史、山田浩司、内橋貴之、安藤敏夫、竹居孝二
- Organizer
  2017年度生命科学系学会合同年次大会　ConBio2017
- Data Source
  KAKENHI-PROJECT-16K10756

1. YAMADA Hiroshi (80325092)

# of Collaborated Projects: 4 results

# of Collaborated Products: 24 results
2. 竹居孝二 (40322226)

# of Collaborated Projects: 2 results

# of Collaborated Products: 22 results
3. WATANABE Masami (70444677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. ASAI Akira (60381737)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 道上宏之 (20572499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 長岡ひかる

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

ABE TADASHI 阿部 匡史

阿部 匡史 アベ タダシ

ABE Tadashi 阿部 匡史

Research Projects

Research Products

Co-Researchers

がん細胞の浸潤転移を制御するダイナミンクロスブリッジ機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the function of novel actin-binding factors in neutrophil phagocytosis and extracellular trap formationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of the anti-invasive drug for treatment of malignant glioma by drug-repositioning of anti-depressant.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of dynamin in actin dynamics: Development of anticancer drugs inhibiting dynamin functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Use of liposomes to study vesicular transport., Methods in Molecular Biology, 6062010

Author(s)

Data Source

[Journal Article] The Lipid-Binding Defective Dynamin 2 Mutant in Charcot-Marie-Tooth Disease Impairs Proper Actin Bundling and Actin Organization in Glomerular Podocytes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Recruitment of Irgb6 to the membrane is a direct trigger for membrane deformation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mutant BIN1-Dynamin 2 complexes dysregulate membrane remodeling in the pathogenesis of centronuclear myopathy2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Imaging‐based evaluation of pathogenicity by novel DNM2 variants associated with centronuclear myopathy2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dynamin 1 is important for microtubule organisation and stabilisation in glomerular podocytes2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Internalization of AMPA-type glutamate receptor in the MIN6 pancreatic beta-cell line2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Phosphorylation of cortactin by cyclin-dependent kinase 5 modulates actin bundling by the dynamin 1-cortactin ring-like complex and formation of filopodia and lamellipodia in NG108-15 glioma-derived cells2019

Author(s)

Journal Title

Data Source

[Journal Article] Dynamic clustering of dynamin-amphiphysin helices regulates membrane constriction and fission coupled with GTP hydrolysis2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Dynamin2 GTPase contributes to invadopodia formation in invasive bladder cancer cells.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Actin bundling by dynamin 2 and cortactin is implicated in cell migration by stabilizing filopodia in human non-small cell lung carcinoma cells.2016

ABE TADASHI 阿部匡史

阿部匡史アベタダシ

ABE Tadashi 阿部匡史