Yokota Harumasa 横田陽匡

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YOKOTA Harumasa 横田陽匡

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Researcher Number	60431417
Other IDs
Affiliation (Current)	2025: 旭川医科大学, 医学部, 准教授 2025: 日本大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 旭川医科大学, 医学部, 准教授 2024: 日本大学, 医学部, 准教授 2019 – 2022: 日本大学, 医学部, 准教授 2018: 日本大学, 医学部, 助教 2011 – 2017: 旭川医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Ophthalmology / Basic Section 56060:Ophthalmology-related / 0906:Surgery related to the biological and sensory functions and related fields Except Principal Investigator Basic Section 56060:Ophthalmology-related / Ophthalmology
Keywords	Principal Investigator 糖尿病網膜症 / プロレニン / 糖尿病 / ペプチドワクチン / ワクチン / （プロ）レニン受容体 / 遺伝子改変ブタ / 若年発症型糖尿病 / 若年発症型成人糖尿病 / 遺伝子改変糖尿病ブタ … More / オートタキシン / ２型糖尿病 / db/db / MODY3 / ブタ / MODY / 若年発症成人型糖尿病 / 耐糖能異常 / 糖尿病性腎症 / 眼疾患 / 糖転移ヘスペリジン / 分散ヘスペレチン / 血管保護 / 神経保護 / 虚血性網膜症 / 虚血網膜 / 酸化ストレス / 網膜虚血再灌流 / 受容体随伴プロレニン系 … More Except Principal Investigator 糖尿病網膜症 / ナノ粒子化点眼 / 虚血再灌流障害 / 微小循環 / 網膜血流 / 一酸化窒素 / 神経血管連関 / 網膜循環調節 / 神経－血管連関 / 網膜微小循環 Less

ペプチドワクチン技術を応用した糖尿病網膜症に対する新規治療法の開発Principal Investigator
- Principal Investigator
  
  横田陽匡
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Asahikawa Medical College
Overcoming Diabetic Retinopathy through Local Control of Oxidative Stress
- Principal Investigator
  
  櫛山暁史
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Meiji Pharmaceutical University
Development of vaccine therapy for diabetic retinopathy, and new model of diabetic retinopathyPrincipal Investigator
- Principal Investigator
  
  YOKOTA Harumasa
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Nihon University
Development of vaccine therapy for prevention of diabetic retinopathyPrincipal Investigator
- Principal Investigator
  
  YOKOTA Harumasa
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0906:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Nihon University
糖尿病網膜症の発症予防のためのワクチン治療の開発Principal Investigator
- Principal Investigator
  
  横田陽匡
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Asahikawa Medical College
Elucidation of regulatory mechanism of neurovascular coupling interaction in retinal circulation and clinical application for early diagnosis of diabetic retinopathy
- Principal Investigator
  
  NAGAOKA Taiji
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Asahikawa Medical College
The development of a new therapy in diabetic retinopathy by application of alpha-glucosylhesperidinPrincipal Investigator
- Principal Investigator
  
  Yokota Harumasa
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Asahikawa Medical College
The development of a new therapy for diabetic retinopathy targeting the receptor-associated prorenin systemPrincipal Investigator
- Principal Investigator
  
  YOKOTA Harumasa
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Asahikawa Medical College

All 2023 2022 2021 2020 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] A pilot study of diabetic retinopathy in a porcine model of maturity onset diabetes of the young type 3 (MODY3)2023
- Author(s)
  Takase K, Yokota H, Ohno A, Watanabe M, Kushiyama A, Kushiyama S, Yamagami S, Nagaoka T
- Journal Title
  
  Exp Eye Res.
  
  Volume: 227 Pages: 109379-109379
- DOI
  10.1016/j.exer.2022.109379
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K02314, KAKENHI-PROJECT-22K09822, KAKENHI-PROJECT-20K09835
[Journal Article] Effect of prorenin peptide vaccine on the early phase of diabetic retinopathy in a murine model of type 2 diabetes2022
- Author(s)
  Yokota Harumasa、Hayashi Hiroki、Hanaguri Junya、Yamagami Satoru、Kushiyama Akifumi、Nakagami Hironori、Nagaoka Taiji
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 1 Pages: e0262568-e0262568
- DOI
  10.1371/journal.pone.0262568
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K02314, KAKENHI-PROJECT-20K09835
[Journal Article] Characteristics of Retinal Neovascularization in Proliferative Diabetic Retinopathy Imaged by Optical Coherence Tomography Angiography.2016
- Author(s)
  Ishibazawa A, Nagaoka T, Yokota H, Takahashi A, Omae T, Song YS, Takahashi T, Yoshida A.
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: 57(14) Pages: 6247-6255
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293352
[Journal Article] Radial Peripapillary Capillary Network Visualized Using Wide-Field Montage Optical Coherence Tomography Angiography.2016
- Author(s)
  Mase T, Ishibazawa A, Nagaoka T, Yokota H, Yoshida A.
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: 57(9)
- NAID
  120005822574
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293352
[Journal Article] Neuroprotective effect of Water-dispersible hesperetin in retinal ischemia reperfusion injury.2016
- Author(s)
  Shimouchi A, Yokota H, Ono S, Matsumoto C, Tamai T, Takumi H, Narayanan SP, Kimura S, Kobayashi H, Caldwell RB, Nagaoka T, Yoshida A.
- Journal Title
  
  Jpn J Ophthalmol
  
  Volume: 60(1) Pages: 51-61
- NAID
  210000170569
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293352
[Journal Article] Systemic Risk Factors in Bilateral Proliferative Diabetic Retinopathy Requiring Vitrectomy.2016
- Author(s)
  Song YS, Nagaoka T*, Omae T, Yokota H, Takahashi A, Yoshida A.
- Journal Title
  
  Retina.
  
  Volume: 36(7) Pages: 1309-1313
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293352
[Journal Article] Neuroprotective effect of water-dispersible hesperetin in retinal ischemia reperfusion injury2016
- Author(s)
  Shimouchi A, Yokota H, Ono S, Matsumoto C, Tamai T, Takumi H, Narayanan SP, Kimura S, Kobayashi H, Caldwell RB, Nagaoka T, Yoshida A
- Journal Title
  
  Japanese Journal of Ophthalmology
  
  Volume: 60 Issue: 1 Pages: 51-61
- DOI
  10.1007/s10384-015-0415-z
- NAID
  210000170569
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25861609
[Journal Article] Optical Coherence Tomography Angiography in Diabetic Retinopathy: A Prospective Pilot Study.2015
- Author(s)
  Ishibazawa A, Nagaoka T, Takahashi A, Omae T, Tani T, Sogawa K, Yokota H, Yoshida A.
- Journal Title
  
  Am J Ophthalmol.
  
  Volume: 160(1) Pages: 35-44
- NAID
  120005837998
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293352
[Journal Article] Serum prorenin levels are not associated with ocular diseases in non-diabetic subjects2015
- Author(s)
  Yokota H
- Journal Title
  
  J Renin Angiotensin Aldosterone Syst
  
  Volume: 16 Issue: 1 Pages: 153-158
- DOI
  10.1016/j.ajo.2015.04.021
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25861609, KAKENHI-PROJECT-26861429
[Journal Article] Imaging of the Corneal Sub-Basal Whorl-Like Nerve Plexus: More Accurate Depiction of the Extent of Corneal Nerve Damage in Patients with Diabetes.2015
- Author(s)
  Utsunomiya T, Nagaoka T, Hanada K, Omae T, Yokota H, Abiko A, Haneda M, Yoshida A.
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: 56(9) Pages: 5417-5423
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293352
[Presentation] プロレニンペプチドワクチンの遺伝子改変糖尿病ブタの網膜血管病変に対する効果2023
- Author(s)
  横田陽匡、林宏樹、高瀬公陽、花栗潤哉、渡辺昌久、大野皓、小熊秀隆、丸山高史、阿部雅紀、櫛山暁史、中神啓徳、山上聡、長岡泰司
- Organizer
  第１２７回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-20K09835
[Presentation] プロレニンペプチドワクチンの血清、房水中の抗体価2022
- Author(s)
  横田陽匡、林宏樹、高瀬公陽、花栗潤哉、渡部昌久、大野皓、小熊秀隆、丸山高史、阿部雅紀、櫛山暁史、中神啓徳、山上聡、長岡泰司
- Organizer
  第126回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-20K09835
[Presentation] 遺伝子改変糖尿病ブタの網膜病変の組織学的検討2022
- Author(s)
  高瀬公陽、横田陽匡、花栗潤哉、渡部昌久、大野皓、櫛山暁史、石館文善、櫛山櫻、山上聡、長岡泰司
- Organizer
  第126回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-20K09835
[Presentation] プロレニンペプチドワクチンの血清、房水中の抗体価2022
- Author(s)
  横田陽匡、林宏樹、高瀬公陽、花栗潤哉、渡辺昌久、大野皓、小熊秀隆、丸山高史、阿部雅紀、櫛山暁史、中神啓徳、山上聡、長岡泰司
- Organizer
  第１２６回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-20K09835
[Presentation] Effect of prorenin peptide vaccine on an early phase of diabetic retinopathy in murine model of type 2 diabetes mellitus2021
- Author(s)
  Harumasa Yokota
- Organizer
  ARVO2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09835
[Presentation] 遺伝子改変糖尿病ブタの網膜血管病変2020
- Author(s)
  横田陽匡
- Organizer
  第124回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-19K21358
[Presentation] The role of renin-angiotensin system in the regulation of retinal arterioles2014
- Author(s)
  Harumasa Yokota
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Orland, USA
- Data Source
  KAKENHI-PROJECT-25861609
[Presentation] 分散ヘスペレチンは虚血性網膜症の神経節細胞死を抑制する2013
- Author(s)
  下内　明人　横田　陽匡
- Organizer
  第１１７回日本眼科学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23791955
[Presentation] Water-dispersible hesperetin prevents ganglion cell loss in the retina after retinal ischemia reperfusion injury2013
- Author(s)
  Akihito Shimouchi, Harumasa Yokota
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-25861609
[Presentation] Water-dispersible hesperetin prevents ganglion cell loss in the retina after retinal ischemia reperfusion injury.2013
- Author(s)
  Akito Shimouch, Harumasa Yokota
- Organizer
  2013 The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Seattle
- Data Source
  KAKENHI-PROJECT-23791955
[Presentation] 分散ヘスペレチンは虚血性網膜症の神経節細胞死を抑制する2013
- Author(s)
  下内昭人、横田陽匡
- Organizer
  第１１７回日本眼科学会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25861609
[Presentation] 非糖尿病患者における血中プロレニン値に関する因子
- Author(s)
  横田陽匡
- Organizer
  第１１６回日本眼科学会総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-23791955
[Presentation] The role of prorenin in microglial activation
- Author(s)
  Yokota H
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Denver in the USA
- Year and Date
  2015-05-03 – 2015-05-08
- Data Source
  KAKENHI-PROJECT-25861609

1. NAGAOKA Taiji (00333691)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. 大谷真一 (70548841)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 高橋淳士 (90422047)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 善岡尊文 (20548854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 中神啓徳 (20325369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 櫛山暁史 (30435820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 木村航 (60452182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 長井紀章 (90411579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yokota Harumasa 横田 陽匡

YOKOTA Harumasa 横田 陽匡

Research Projects

Research Products

Co-Researchers

ペプチドワクチン技術を応用した糖尿病網膜症に対する新規治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Overcoming Diabetic Retinopathy through Local Control of Oxidative Stress

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of vaccine therapy for diabetic retinopathy, and new model of diabetic retinopathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of vaccine therapy for prevention of diabetic retinopathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

糖尿病網膜症の発症予防のためのワクチン治療の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of regulatory mechanism of neurovascular coupling interaction in retinal circulation and clinical application for early diagnosis of diabetic retinopathy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The development of a new therapy in diabetic retinopathy by application of alpha-glucosylhesperidinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The development of a new therapy for diabetic retinopathy targeting the receptor-associated prorenin systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A pilot study of diabetic retinopathy in a porcine model of maturity onset diabetes of the young type 3 (MODY3)2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of prorenin peptide vaccine on the early phase of diabetic retinopathy in a murine model of type 2 diabetes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characteristics of Retinal Neovascularization in Proliferative Diabetic Retinopathy Imaged by Optical Coherence Tomography Angiography.2016

Author(s)

Journal Title

Data Source

[Journal Article] Radial Peripapillary Capillary Network Visualized Using Wide-Field Montage Optical Coherence Tomography Angiography.2016

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Neuroprotective effect of Water-dispersible hesperetin in retinal ischemia reperfusion injury.2016

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Systemic Risk Factors in Bilateral Proliferative Diabetic Retinopathy Requiring Vitrectomy.2016

Author(s)

Journal Title

Yokota Harumasa 横田陽匡

YOKOTA Harumasa 横田陽匡