Nishimura Yoshio 西村良夫

… Alternative Names

NISHIMURA Yoshio 西村良夫

Less

Researcher Number	60431516
Other IDs
Affiliation (Current)	2025: 奥羽大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2024 – 2025: 奥羽大学, 薬学部, 准教授 2015 – 2018: 安田女子大学, 薬学部, 講師 2012 – 2014: 安田女子大学, 薬学部, 助教 2006 – 2008: 東北大学, 大学院・薬学研究科, 助手 2006: 東北大学, 大学院薬学研究科, 助手
Review Section/Research Field	Principal Investigator Drug development chemistry / Basic Section 37030:Chemical biology-related / Bio-related chemistry / Organic chemistry Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Chemical pharmacy
Keywords	Principal Investigator ジヒドロピリミジン / 細胞・組織 / 薬理学 / 生理活性 / 有機化学 / 薬学 / RXR / RAR / ベキサロテン / レチノイン酸 … More / タミバロテン / レチノイド / ヘテロ環 / 酸化 / 活性酸素 / 蛍光プローブ / ピリミジン / β，β-二置換α-アミノ酸 / 不斉四級中心 / β-ヘテロα,α-二置換α-アミノ酸 / 不斉四級炭素 / アジリジン / 1,3-ジオール / 非対称化 / リパーゼ触媒 / β-ヘテロ置換α,α-二置換α-アミノ酸 / Wittig反応 / プロパルギルイリド / ガリウムエノラート / 有機金属塩基 / メチン選択性 / 4配位錯体 / ケトン / スルホニウム塩 / (Z)-選択性 / Corey-Chaykovsky反応 / 脱プロトン化 / トリアルキルガリウム … More Except Principal Investigator ヒト骨髄系白血病細胞株 / アポトーシス / RXRアゴニス / レチノイドX受容体 / ジヒドロピリミジン誘導体 / アルキニルホスフィン / チオアセチレン / CH結合活性化 / イオウ単体 / チオイソニトリル / CS結合切断 / アルキルチオ交換反応 / 酸化還元反応 / ホスホニウム塩 / パラジウム触媒 / ロジウム触媒 / 有機イオウ化合物 / 芳香族スルフィド / 芳香族スルフイド / フルオロベンゼン / 有機合成 / 触媒 / 遷移金属 / 単結合メタセシス / 付加反応 / リン / イオウ / 遷移金属触媒 Less

ジヒドロピリミジン誘導体の構造活性相関による RXR アゴニストの創製Principal Investigator
- Principal Investigator
  
  西村良夫
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Ohu University
RXRを分子標的としたジヒドロピリミジン誘導体の抗悪性腫瘍薬への基礎的研究
- Principal Investigator
  
  菊地秀与
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Josai University
Development of novel dihydropyrimidine retinoids for medicinal chemistry and drug dicoveryPrincipal Investigator
- Principal Investigator
  
  Nishimura Yoshio
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Yasuda Women's University
Development of dihydropyrimidine fluorescent probe to detect reactive oxygen species for analysis of in vivo oxidationPrincipal Investigator
- Principal Investigator
  
  NISHIMURA Yoshio
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Yasuda Women's University
Synthesis of beta-heterosubstituted alpha,alpha-disubstituted alpha-amino acid derivatives via enzyme-catalyzed desymmetrizationPrincipal Investigator
- Principal Investigator
  
  NISHIMURA Yoshio
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Yasuda Women's University
新しい有機金属強塩基:トリアルキルガリウムPrincipal Investigator
- Principal Investigator
  
  西村良夫
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Organic chemistry
- Research Institution
  Tohoku University
Organoheteroatom Chemistry Based on Transition Metal Catalysis
- Principal Investigator
  
  YAMAGUCHI Masahiko
- Project Period (FY)
  2004 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tohoku University

All 2019 2018 2017 2016 2015 2014 2013 2012 2008 2006 2005 2004 Other

All Journal Article Presentation

[Journal Article] Antitumor effect of palmitic acid‐conjugated Dsi RNA for colon cancer in a mouse subcutaneous tumor model2019
- Author(s)
  Kubo Takanori、Nishimura Yoshio、Hatori Yuta、Akagi Reiko、Mihara Keichiro、Yanagihara Kazuyoshi、Seyama Toshio
- Journal Title
  
  Chemical Biology & Drug Design
  
  Volume: 93 Issue: 4 Pages: 570-581
- DOI
  10.1111/cbdd.13454
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K01939, KAKENHI-PROJECT-16K08335, KAKENHI-PROJECT-19K05703
[Journal Article] Experimental and theoretical studies on thermodynamics and properties of tautomers of 2-substituted 6(4)-methyl-1,4(1,6)-dihydropyrimidine-5-carboxylates2018
- Author(s)
  Hidetsura Cho, Yoshio Nishimura, Hiroshi Ikeda, Mitsuhiro Asakura, Shinji Toyota
- Journal Title
  
  Tetrahedron
  
  Volume: 74 Issue: 20 Pages: 2405-2413
- DOI
  10.1016/j.tet.2018.03.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08335
[Journal Article] Convergent synthesis of 4,6-unsubstituted 5-acyl-2-aminodihydropyrimidines using Weinreb amide.2017
- Author(s)
  Nishimura Y, Kubo T, Okamoto Y, Cho H.
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 58 Issue: 45 Pages: 4236-4239
- DOI
  10.1016/j.tetlet.2017.09.064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K01939, KAKENHI-PROJECT-16K08335
[Journal Article] Convergent synthesis of 4,6-unsubstituted 5-acyl-2-phenyldihydropyrimidines by substitution reactions of Weinreb amide group of tetrahydropyrimidines2016
- Author(s)
  Yoshio Nishimura, Takanori Kubo, Yasuko Okamoto, Hidetsura Cho
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 57 Issue: 40 Pages: 4492-4495
- DOI
  10.1016/j.tetlet.2016.08.077
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K08335
[Journal Article] Synthesis of 4,6-Unsubstituted 2-Aminodihydropyrimidine-5-Carboxylates via Sequential Staudinger/Aza-Wittig/Cyclization Reactions2015
- Author(s)
  Y. Nishimura, H. Cho
- Journal Title
  
  Synlett
  
  Volume: (in press) Issue: 02 Pages: 233-237
- DOI
  10.1055/s-0034-1378932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790122, KAKENHI-PROJECT-26810095
[Journal Article] Expression and Substrate Range of <i>Streptomyces</i> Vanillate Demethylase2014
- Author(s)
  Motohiro Nishimura, Yoshio Nishimura, Chinatsu Abe, and Mayuko Kohhata
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 37 Issue: 9 Pages: 1564-1568
- DOI
  10.1248/bpb.b14-00337
- NAID
  130004057438
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26810095
[Journal Article] Synthesis of 4-unsubstituted dihydropyrimidines having acyl and alkoxycarbonyl groups at 5-and 6-positions by cyclization-elimination reactions using 1,3-diaza-1,3-butadienes2014
- Author(s)
  Y. Nishimura, H. Cho
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 55 Pages: 411-414
- Data Source
  KAKENHI-PROJECT-24790122
[Journal Article] Synthesis of 4-unsubstituted dihydropyrimidines having acyl and alkoxycarbonyl groups at 5- and 6-positions by cyclization-elimination reactions using 1,3-diza-1,3-butadienes2014
- Author(s)
  Y. Nishimura, H. Cho
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 55 Issue: 2 Pages: 411-414
- DOI
  10.1016/j.tetlet.2013.11.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790122
[Journal Article] Expression and Substrate Range of Streptomyces Vanillate Demethylase2014
- Author(s)
  M. Nishimura, Y. Nishimura, C. Abe, M. Kohhata
- Journal Title
  
  Biological & Pharmaceutical Bulletin
  
  Volume: 37 Pages: 1564-1568
- NAID
  130004057438
- Data Source
  KAKENHI-PROJECT-24790122
[Journal Article] Synthesis of novel 2-phenyl-5-substituted dihydropyrimidines using 2-phenyl-1,3-diaza-1,3-butadienes and electron-deficient olefins2012
- Author(s)
  Yoshio Nishimura, Yoshizumi Yasui, Satoshi Kobayashi, Masahiko Yamaguchi, Hidetsura Cho
- Journal Title
  
  Tetrahedron
  
  Volume: 68 Issue: 16 Pages: 3342-3350
- DOI
  10.1016/j.tet.2012.02.064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24550061, KAKENHI-PROJECT-24790122
[Journal Article] Synthesis of novel 2-phenyl-5substituted dihydropyrimidines using 2-phenyl-1,3-diaza-1,3-butadienes and electron-deficient olefins2012
- Author(s)
  Y. Nishimura, Y. Yasui, S. Kobayashi, M. Yamaguchi, H. Cho
- Journal Title
  
  Tetrahedron
  
  Volume: 68 Pages: 3342-3350
- Data Source
  KAKENHI-PROJECT-24790122
[Journal Article] Trichlorogallium and trialkylgalliums in organic synthesis.2008
- Author(s)
  M. Yamaguchi and Y. Nishimura
- Journal Title
  
  Chem. Commun. 35
  
  Pages: 35-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109001
[Journal Article] Trichlorogallium and trialkylgalliums in organic synthesis2008
- Author(s)
  M. Yamaguchi and Y. Nishimura
- Journal Title
  
  Chem. Commun.
  
  Pages: 35-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109001
[Journal Article] (Z)-Selective Witting and Corey-Chaykovsky reactions of propargyl ylides using trialkylgallium bases2008
- Author(s)
  Y. Nishimura, T. Shiraishi, and M. Yamaguchi
- Journal Title
  
  Tetrahedron Letters 49
  
  Pages: 3492-3495
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109001
[Journal Article] Trichlorogallium and Trialkylgalliums in Organic Synthesis.2008
- Author(s)
  M. Yamaguchi, Y. Nishimura
- Journal Title
  
  Chemical Communications
  
  Pages: 35-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18850004
[Journal Article] Gallium Trichloride-Promoted Ethynylation Reaction of 1,4-Dienes.2008
- Author(s)
  Y. Nishimura, M. Kiryu, K. Suwa, R. Amemiya, M. Yamaguchi
- Journal Title
  
  Advanced Synthesis & Catalysis (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18850004
[Journal Article] (Z)-Selective Witting and Corey-Chaykovsky Reactions of Propargyl Ylides Using Trialkylgallium Bases.2008
- Author(s)
  Y. Nishimura, T. Shiraishi, M. Yamaguchi
- Journal Title
  
  Tetrahedron Letters 49(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18850004
[Journal Article] α-Ethynylation Reaction of Ketones Using Catalytic Amounts of Trialkylgallium Base.2006
- Author(s)
  Y.Nishimura, R.Amemiya, M.Yamaguchi
- Journal Title
  
  Tetrahedron Lett. 47
  
  Pages: 1839-1843
- Data Source
  KAKENHI-PROJECT-16109001
[Journal Article] α- Ethynylation Reaction of Ketones Using Catalytic Amounts of Trialkylgallium Base2006
- Author(s)
  Y. Nishimura, R. Amemiya, and M. Yamaguchi
- Journal Title
  
  Tetrahedron Lett. 47
  
  Pages: 1839-1843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109001
[Journal Article] Triethylgallium as Non-Nucleophilic Base to Generate Enolates from Ketones2006
- Author(s)
  Y.Nishimura, Y.Miyake, R.Amemiya, M.Yamaguchi
- Journal Title
  
  Organic Letters 8
  
  Pages: 5077-5080
- Data Source
  KAKENHI-PROJECT-18850004
[Journal Article] α- Ethynylation Reaction of Ketones Using Catalytic Amounts of Trialkylgallium Base.2006
- Author(s)
  Y. Nishimura, R. Amemiya, and M. Yamaguchi,
- Journal Title
  
  Tetrahedron Lett. 47
  
  Pages: 1839-1843
- Data Source
  KAKENHI-PROJECT-16109001
[Journal Article] Triethylgallium as Non-Nucleophilic Base to Generate Enolates from Ketones.2006
- Author(s)
  Y. Nishimura, Y. Miyake, R. Amemiya, and M. Yamaguchi
- Journal Title
  
  Org. Lett 8
  
  Pages: 5077-5080
- Data Source
  KAKENHI-PROJECT-16109001
[Journal Article] One-Step Synthesis of Triethynylvinylmethanes and Tetraethynylmethanes by GaC_3 - Promoted Diethynylation of 1,4 - Enynes and 1,4 - Diynes2005
- Author(s)
  R. Amemiya, K. Suwa, J. Toriyama, Y. Nishimura, and M. Yamaguchi
- Journal Title
  
  J. Am. Chem. Soc. 127
  
  Pages: 8252-8253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109001
[Journal Article] One-Step Synthesis of Triethynylvinylmethanes and Tetraethynylmethanes by GaCl_3-Promoted Diethynylation of 1,4-Enynes and 1,4-Diynes.2005
- Author(s)
  R.Amemiya, K.Suwa, J.Toriyama, Y.Nishimura, M.Yamaguchi
- Journal Title
  
  J.Am.Chem.Soc. 127
  
  Pages: 8252-8253
- Data Source
  KAKENHI-PROJECT-16109001
[Journal Article] GaCl_3-Catalyzed α-Ethenylation Reaction of Ketone.2004
- Author(s)
  Ryo Amemiya, Yoshio Nishimura, Masahiko Yamaguchi
- Journal Title
  
  SYNTHESIS 9
  
  Pages: 1307-1314
- Data Source
  KAKENHI-PROJECT-16109001
[Presentation] HL-60細胞に対する新規dihydropyrimidine誘導体の細胞毒性誘導2019
- Author(s)
  菊地秀与、西村良夫、久保貴紀、袁博、須永克佳、日比野康英、長秀連
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K08335
[Presentation] 1,4-および1,6-ジヒドロピリミジン互変異性体の熱力学安定性に関する実験的・理論的研究2019
- Author(s)
  西村良夫、朝倉光博、池田宏、豊田真司、長秀連
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K08335
[Presentation] ジヒドロピリミジン誘導体の互変異性体の構造と熱力学的安定性に関する研究2019
- Author(s)
  池田宏、朝倉光博、西村良夫、長秀連、豊田真司
- Organizer
  日本化学会第99春季年会
- Data Source
  KAKENHI-PROJECT-16K08335
[Presentation] 強力なRNAi効果を有するパルミチン酸コンジュゲートDicer-substrate siRNAの開発2019
- Author(s)
  久保貴紀、西村良夫、栁原五吉、瀬山敏雄
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K08335
[Presentation] 酸触媒を用いた閉環反応による 6-無置換ジヒドロピリミジンの合成2018
- Author(s)
  西村良夫、極樂寺侑希、久保貴紀、長秀連
- Organizer
  第57回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-16K08335
[Presentation] Weinrebアミド基を利用する2-アミノ-5-アシルジヒドロピリミジンの収束的合成2018
- Author(s)
  西村良夫、久保貴紀、長秀連
- Organizer
  日本化学会第98春季年会（2018）
- Data Source
  KAKENHI-PROJECT-16K08335
[Presentation] アルケニルアジドの連続的反応とWeinrebアミド基への求核置換反応を利用した 2-アミノ-5-アシルジヒドロピリミジンの合成2017
- Author(s)
  西村良夫、長秀連
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K08335
[Presentation] Weinrebアミド基を有する4,6-無置換ジヒドロピリミジン誘導体の合成と5-アシル体への変換反応2017
- Author(s)
  西村良夫、久保貴紀、長秀連
- Organizer
  第56回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-16K08335
[Presentation] Weinrebアミド基を利用する2-アミノ-5-アシルジヒドロピリミジンの合成2017
- Author(s)
  西村良夫、長秀連
- Organizer
  第47回複素環化学討論会
- Data Source
  KAKENHI-PROJECT-16K08335
[Presentation] ラニレスタット鍵中間体（光学活性環状イミド）の立体選択的合成2017
- Author(s)
  西村良夫、佐々木千尋、西博行、生中雅也
- Organizer
  日本プロセス化学会 2017サマーシンポジウム
- Data Source
  KAKENHI-PROJECT-16K08335
[Presentation] ラニレスタット鍵中間体（光学活性環状イミド）の立体選択的合成2016
- Author(s)
  西村良夫、佐々木千尋、西博行、生中雅也
- Organizer
  第34回メディシナルケミストリーシンポジウム
- Place of Presentation
  つくば
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K08335
[Presentation] Weinrebアミド基を利用する 4,6-無置換 2-アリール-5-アシルジヒドロピリミジン誘導体の収束的合成2016
- Author(s)
  西村良夫、長秀連
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26810095
[Presentation] 新しい糖尿病合併症治療薬ラニレスタットの合成研究2015
- Author(s)
  西村良夫
- Organizer
  第 132 回日本薬学会中国四国支部例会
- Place of Presentation
  安田女子大学（広島）
- Year and Date
  2015-01-10
- Invited
- Data Source
  KAKENHI-PROJECT-26810095
[Presentation] Weinrebアミド基を利用する4,6-無置換 5-アシルジヒドロピリミジンの合成2015
- Author(s)
  西村良夫、長秀連
- Organizer
  第45回複素環化学討論会
- Place of Presentation
  早稲田大学国際会議場
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-26810095
[Presentation] リパーゼによるdesymmetrizationを利用したN-Cbz (S)-α-メチルセリンの実用的合成プロセスの開発2014
- Author(s)
  西村良夫、雲地早紀、久常由加里、岡水涼、森川瞳、西博行、生中雅也
- Organizer
  日本プロセス化学会2014サマーシンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790122
[Presentation] 5,6-位にケトン、エステル基を有する4-無置換ジヒドロピリミジン誘導体の合成2014
- Author(s)
  西村良夫、長秀連
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24790122
[Presentation] 5,6-位にケトン、エステル基を有する4-無置換ジヒドロピリミジン誘導体の合成」（口頭発表2014
- Author(s)
  西村良夫、長秀連
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24790122
[Presentation] 1,3-ジアザ-1,3-ブタジエンとオレフィンの環化反応を利用したジヒドロピリミジン誘導体の新しい合成法の開発2013
- Author(s)
  西村良夫、安井義純、小林学史、山口雅彦、長秀連
- Organizer
  第103回有機合成シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790122
[Presentation] 1,3-ジアザ-1,3-ブタジエンを用いる2,5-二置換ジヒドロピリミジンの合成2012
- Author(s)
  西村良夫、安井義純、小林学史、山口雅彦、長秀連
- Organizer
  第42回複素環化学討論会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24790122
[Presentation] Construction of dihydropyrimidine skeleton using 1,2,4-trisubstituted-1,3-diaza-1,3-b utadienes and electron-deficientolefins2012
- Author(s)
  H. Cho, Y. Nishimura, Y. Yasui, S.Kobayashi, M. Yamaguchi
- Organizer
  6th Spanish Portuguese Japanese Organic Chemistry Symposium (SPJ-OCS)
- Place of Presentation
  Lisbon, Portuguese
- Data Source
  KAKENHI-PROJECT-24790122
[Presentation] 1,3-ジアザ-1,3-ブタジエンを用いる環化反応を利用した新規2,5-二置換ジヒドロピリミジン誘導体の合成2012
- Author(s)
  西村良夫、安井義純、小林学史、山口雅彦、長　秀連
- Organizer
  第38回反応と合成の進歩シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790122
[Presentation] CONSTRUCTION OF DIHYDROPYRIMIDINE SKELETON USING 1,2,4-TRISUBSTITUTED-1,3-DIAZA-1,3-BUTADIENES AND ELECTRON-DEFICIENT OLEFINS2012
- Author(s)
  Cho, H., Nishimura, Y., Yasui, Y., Kobayashi, S., Yamaguchi, M.
- Organizer
  6th Spanish Portuguese Japanese Organic Chemistry Symposium
- Place of Presentation
  Lisbon, Portuguese
- Data Source
  KAKENHI-PROJECT-24790122
[Presentation] 1,3-ジアザ-1,3-ブタジエンを用いる環化反応を利用した新規2,5二置換ジヒドロピリミジン誘導体の合成2012
- Author(s)
  西村良夫、安井義純、小林学史、山口雅彦、長秀連
- Organizer
  第38回反応と合成の進歩シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790122
[Presentation] リパーゼによる desymmetrization を利用した N-Cbz (S)-α-メチルセリンの実用的合成プロセスの開発
- Author(s)
  西村良夫、雲地早紀、久常由加里、岡水涼、森川瞳、西博行、生中雅也
- Organizer
  日本プロセス化学会 2014 サマーシンポジウム
- Place of Presentation
  タワーホール船堀（東京）
- Year and Date
  2014-07-31 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-26810095
[Presentation] 連続的 Staudinger／Aza-Wittig／環化反応による 4,6-無置換 2-アミノジヒドロピリミジン-5-エステルの合成
- Author(s)
  西村良夫、長秀連
- Organizer
  日本薬学会第 135 年会
- Place of Presentation
  神戸学院大学（神戸）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26810095
[Presentation] 連続的Aza-Wittig／環化反応による4,6-無置換ジヒドロピリミジンの合成
- Author(s)
  西村良夫、長秀連
- Organizer
  第 44 回複素環化学討論会
- Place of Presentation
  札幌市民ホール（札幌）
- Year and Date
  2014-09-10 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-26810095

1. 菊地秀与 (60614055)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. YAMAGUCHI Masahiko (30158117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
3. AMEMIYA Ryo (20359532)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. 久保貴紀 (90435751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
5. 袁博 (10328552)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 岩田直洋 (50552759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 新井理絵 (80909507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Cho Hidetsura

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
9. 安井義純

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 柳原五吉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nishimura Yoshio 西村 良夫

NISHIMURA Yoshio 西村 良夫

Research Projects

Research Products

Co-Researchers

ジヒドロピリミジン誘導体の構造活性相関による RXR アゴニストの創製Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

RXRを分子標的としたジヒドロピリミジン誘導体の抗悪性腫瘍薬への基礎的研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel dihydropyrimidine retinoids for medicinal chemistry and drug dicoveryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of dihydropyrimidine fluorescent probe to detect reactive oxygen species for analysis of in vivo oxidationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Synthesis of beta-heterosubstituted alpha,alpha-disubstituted alpha-amino acid derivatives via enzyme-catalyzed desymmetrizationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新しい有機金属強塩基:トリアルキルガリウムPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Organoheteroatom Chemistry Based on Transition Metal Catalysis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Antitumor effect of palmitic acid‐conjugated Dsi RNA for colon cancer in a mouse subcutaneous tumor model2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Experimental and theoretical studies on thermodynamics and properties of tautomers of 2-substituted 6(4)-methyl-1,4(1,6)-dihydropyrimidine-5-carboxylates2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Convergent synthesis of 4,6-unsubstituted 5-acyl-2-aminodihydropyrimidines using Weinreb amide.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Convergent synthesis of 4,6-unsubstituted 5-acyl-2-phenyldihydropyrimidines by substitution reactions of Weinreb amide group of tetrahydropyrimidines2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthesis of 4,6-Unsubstituted 2-Aminodihydropyrimidine-5-Carboxylates via Sequential Staudinger/Aza-Wittig/Cyclization Reactions2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression and Substrate Range of <i>Streptomyces</i> Vanillate Demethylase2014

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

Nishimura Yoshio 西村良夫

NISHIMURA Yoshio 西村良夫