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TAKAMOTO Iseki  高本 偉碩

ORCIDConnect your ORCID iD *help
Researcher Number 60431871
Other IDs
Affiliation (Current) 2025: 東京医科大学, 医学部, 准教授
2025: 国際医療福祉大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help 2020: 国際医療福祉大学, 医学部, 准教授
2018 – 2019: 公益社団法人地域医療振興協会(地域医療研究所), 練馬光が丘病院, 内科医師
2014 – 2017: 東京大学, 医学部附属病院, 助教
2013: 東京大学, 医学部附属病院, 特任助教
2012: 東京大学, 医学部附属病院, 助教
2011: 東京大学, 医学部附属病院, 特任助教
Review Section/Research Field
Principal Investigator
Metabolomics / Basic Section 54040:Metabolism and endocrinology-related
Except Principal Investigator
Metabolomics
Keywords
Principal Investigator
膵β細胞 / 2型糖尿病 / インスリン分泌 / KCNQ1 / 疾患感受性遺伝子 / Tcf7l2 / インスリン / UBE2E2 / 疾患モデル動物 / 糖尿病 / 糖質代謝異常 / エネルギー … More
Except Principal Investigator
… More インスリン分泌刺激物質 / 脂肪分解 / インスリン / メタボローム解析 / リパーゼ / 脂肪細胞 / インスリン分泌 / 脂質 / 糖尿病 Less
  • Research Projects

    (5 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (18 People)
  •  Functional analysis of type 2 diabetes susceptibility genes using animal disease modelsPrincipal Investigator

    • Principal Investigator
      TAKAMOTO ISEKI
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      International University of Health and Welfare
      Japan Association for Development of Community Medicine
  •  Physiological and pathophysiological roles of KCNQ1 as a susceptibility gene for type 2 diabetes mellitusPrincipal Investigator

    • Principal Investigator
      Takamoto Iseki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Physiological and pathophysiological roles of Tcf7l2 in pancreatic beta cells in a murine modelPrincipal Investigator

    • Principal Investigator
      TAKAMOTO ISEKI
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Molecular identity and mechanisms of lipolysis-stimulated insulin secretion

    • Principal Investigator
      OKAZAKI Hiroaki
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Physiological and pathophysiological roles of Tcf7l2 in pancreaticβ cell in type 2 diabetesPrincipal Investigator

    • Principal Investigator
      TAKAMOTO Iseki
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Book

  • [Book] 糖尿病学2014 (2型糖尿病遺伝子TCF7L2の機能を巡って)2014

    • Author(s)
      高本 偉碩
    • Total Pages
      152
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-25860741
  • [Journal Article] TCF7L2 in mouse pancreatic beta cells plays a crucial role in glucose homeostasis by regulating beta cell mass.2014

    • Author(s)
      Takamoto I, Kubota N, Nakaya K, Kumagai K, Hashimoto S, Kubota T, Inoue M, Kajiwara E, Katsuyama H, Obata A, Sakurai Y, Iwamoto M, Kitamura T, Ueki K, Kadowaki T
    • Journal Title

      Diabetologia

      Volume: 57 Issue: 3 Pages: 542-553

    • DOI

      10.1007/s00125-013-3131-6

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390232, KAKENHI-PROJECT-25221307, KAKENHI-PROJECT-25461371, KAKENHI-PROJECT-25860741
  • [Journal Article] Wntシグナルと膵内分泌細胞分化2013

    • Author(s)
      高本偉碩
    • Journal Title

      内分泌・糖尿病・代謝内科

      Volume: 36 Pages: 204-210

    • Data Source
      KAKENHI-PROJECT-23791017
  • [Presentation] 糖尿病関連遺伝子UBE2E2の膵β細胞における役割2021

    • Author(s)
      桜井賛孝, 窪田直人, 高本偉碩, 和田亘弘, 林高則, 相原允一, 窪田哲也, 笹子敬洋, 門脇孝, 山内敏正
    • Organizer
      第41回日本肥満学会
    • Data Source
      KAKENHI-PROJECT-18K08466
  • [Presentation] 糖尿病関連遺伝子UBE2E2の膵β細胞における役割2020

    • Author(s)
      桜井賛孝, 窪田直人, 高本偉碩, 和田亘弘, 林高則, 窪田哲也, 笹子敬洋, 門脇孝, 山内敏正
    • Organizer
      第93回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K08466
  • [Presentation] 糖尿病関連遺伝子UBE2E2の膵β細胞における役割2020

    • Author(s)
      桜井賛孝, 窪田直人, 高本偉碩, 和田亘弘, 林高則, 窪田哲也, 笹子敬洋, 門脇孝, 山内敏正
    • Organizer
      第63回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-18K08466
  • [Presentation] 新規糖尿病関連遺伝子UBE2E2の膵β細胞における役割2019

    • Author(s)
      桜井賛孝, 窪田直人, 高本偉碩, 和田亘弘, 門脇孝, 山内敏正
    • Organizer
      第62回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-18K08466
  • [Presentation] 新規糖尿病関連遺伝子UBE2E2の膵β細胞における役割2018

    • Author(s)
      桜井賛孝, 高本偉碩, 和田亘弘, 塩田清二, 窪田直人, 門脇孝
    • Organizer
      第61回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-18K08466
  • [Presentation] 2型糖尿病感受性遺伝子KCNQ1の機能解析2018

    • Author(s)
      高本偉碩, 窪田直人, 中屋恵三, 桜井賛孝, 植木浩二郎, 門脇孝
    • Organizer
      第61回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-18K08466
  • [Presentation] モデル動物を用いたKCNQ1遺伝子変異と耐糖能に関する検討2017

    • Author(s)
      高本 偉碩
    • Organizer
      第60回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-15K09377
  • [Presentation] KCNQ1遺伝子変異と耐糖能 -モデル動物を用いた検討-2016

    • Author(s)
      高本偉碩
    • Organizer
      第59回日本糖尿病学会年次学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-15K09377
  • [Presentation] Functional analysis of type 2 diabetes susceptibility gene2016

    • Author(s)
      高本偉碩
    • Organizer
      第59回日本糖尿病学会年次学術集会
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K09377
  • [Presentation] 2型糖尿病疾患感受性遺伝子の機能解析2015

    • Author(s)
      高本偉碩
    • Organizer
      第29回日本糖尿病・肥満動物学会年次学術集会
    • Place of Presentation
      京都
    • Year and Date
      2015-02-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-25860741
  • [Presentation] KCNQ1の機能低下型変異の同定と耐糖能との関連2015

    • Author(s)
      高本 偉碩
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      下関
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-15K09377
  • [Presentation] 膵β細胞のTcf7l2は糖代謝と膵β細胞量を制御する2014

    • Author(s)
      高本偉碩
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-05-23
    • Data Source
      KAKENHI-PROJECT-25860741
  • [Presentation] 膵β細胞において2型糖尿病疾患感受性遺伝子Tcf7l2が担う役割2014

    • Author(s)
      高本偉碩
    • Organizer
      第87回内分泌学会学術総会
    • Place of Presentation
      福岡
    • Year and Date
      2014-04-24
    • Data Source
      KAKENHI-PROJECT-25860741
  • [Presentation] Role of Tcf7l2- Mediated Pathway in Pancreatic Beta Cell In Vivo2012

    • Author(s)
      ISEKI TAKAMOTO
    • Organizer
      ADA's 72nd Scientific Sessions
    • Place of Presentation
      Philadelphia, 米国
    • Year and Date
      2012-06-09
    • Data Source
      KAKENHI-PROJECT-23791017
  • [Presentation] 2型糖尿病感受性遺伝子Tcf712が膵β細胞で担う役割の解明2012

    • Author(s)
      高本偉碩
    • Organizer
      第55回日本糖尿病学会年次学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2012-05-19
    • Data Source
      KAKENHI-PROJECT-23791017
  • [Presentation] 膵β細胞のTcf7l2は膵β細胞量維持に重要な役割を果たしている2011

    • Author(s)
      高本偉碩
    • Organizer
      第61回日本体質医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-10-08
    • Data Source
      KAKENHI-PROJECT-23791017
  • [Presentation] 膵β細胞のTcf7l2は膵β細胞量維持に重要な役割を果たしている2011

    • Author(s)
      高本偉碩
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-20
    • Data Source
      KAKENHI-PROJECT-23791017
  • [Presentation] 膵β細胞において2 型糖尿病疾患感受性遺伝子Tcf7l2 が担う役割の解明

    • Author(s)
      高本偉碩
    • Organizer
      第56回日本糖尿病学会年次学術集会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-25860741
  • [Presentation] 膵β細胞において2 型糖尿病疾患感受性遺伝子Tcf7l2 が担う役割の解明

    • Author(s)
      高本偉碩
    • Organizer
      第86回日本内分泌学会学術総会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-25860741
  • [Presentation] Role of Tcf7l2-Mediated Pathway in Pancreatic Beta Cell In Vivo

    • Author(s)
      ISEKI TAKAMOTO
    • Organizer
      ADA's 72nd Scientific Sessions
    • Place of Presentation
      Philadelphia, 米国
    • Data Source
      KAKENHI-PROJECT-23791017
  • [Presentation] 2型糖尿病感受性遺伝子Tcf712が膵β細胞で担う役割の解明

    • Author(s)
      高本 偉碩
    • Organizer
      第55回日本糖尿病学会年次学術集会
    • Place of Presentation
      横浜, 日本
    • Data Source
      KAKENHI-PROJECT-23791017
  • 1.  桜井 賛孝 (70748376)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 2.  KUBOTA Naoto
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 3.  NAKAYA Keizo
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  KUMAGAI Katsuyoshi
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  KADOWAKI Takashi
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  KUBOTA Tetsuya
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  INOUE Mariko
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  IWAMOTO Masahiko
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  UEKI Kohjiro
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  小畑 淳史
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  OKAZAKI Hiroaki (80610211)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  TAKANASHI Mikio (70610799)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  YOSHIDA Masashi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  HARA Kazuo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  橋本 信嗣
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  梶原 栄二
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  勝山 修行
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  北村 忠弘
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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