Kitaguchi Tetsuya 北口哲也

… Alternative Names

KITAGUCHI TETSUYA 北口哲也

KITAGUCHI Tetsuya 北口哲也

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Researcher Number	60432374
Other IDs
Affiliation (Current)	2025: 東京科学大学, 総合研究院, 准教授
Affiliation (based on the past Project Information) *help	2017 – 2024: 東京工業大学, 科学技術創成研究院, 准教授 2017: 東京工業大学, 科学技術創成研究院, 研究員 2016: 早稲田大学, 総合研究機構, 主任研究員(研究院准教授) 2014 – 2015: 早稲田大学, 付置研究所, 准教授 2013 – 2015: 早稲田大学, 重点領域研究機構, 准教授 … More 2011: 早稲田大学, 重点領域研究機構, 准教授 2010: 独立行政法人理化学研究所, 細胞機能探索技術開発チーム, 客員研究員 2008: The Institute of Physical and Chemical Research, 細胞機能探索技術開発チーム, 客員研究員 2007: The Institute of Physical and Chemical Research, 細胞機能探索技術開発チーム, 客員研究員 Less
Review Section/Research Field	Principal Investigator Biomolecular chemistry / General anatomy (including Histology/Embryology) / Basic Section 27040:Biofunction and bioprocess engineering-related Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / General physiology / Transformative Research Areas, Section (III) / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields / Plant molecular biology/Plant physiology
Keywords	Principal Investigator 蛍光タンパク質 / GFP / 抗体 / バイオセンサー / 可視化 / バイオイメージング / タンパク質工学 / 機械学習 / センサー / プロテインエンジニアリング … More / 植物ホルモン / グルコース / ATP / プローブ / 共焦点レーザー顕微鏡 / リーリン / 層構造 / 神経系の発達と老化 / 細胞内・細胞間情報伝達 / 分子神経生物学 / 神経発生・分化・異常 / 細胞内情報伝達 / FRET / 顕微鏡技術 / 形態形成 / リン酸化 / 大脳皮質 / トランスジェニック / 造血 / 血液 / 分化 / 発生 / ミエロイド / ゼブラフィッシュ / 形態形成学 / 発生学 … More Except Principal Investigator イメージング / 消化管ホルモン / 腸内細菌 / 発現制御 / シグナル伝達 / 開口分泌 / 定量解析 / エピゲノム / cis-trans制御 / 花発生 / 転写制御モジュール / ヒストン修飾 / 増殖抑制 / 幹細胞 / プログラムセルデス / 生理学 / 発生・分化 / グレリン / 開口放出 Less

機械学習を活用したユニバーサルな基盤構造創出による蛍光免疫センサーの迅速開発Principal Investigator
- Principal Investigator
  
  北口哲也
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  Tokyo Institute of Technology
腸内細菌代謝物による認知的柔軟性制御における消化管ホルモンを介した分子機構の解析
- Principal Investigator
  
  坪井貴司
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  The University of Tokyo
両性花における動物を利用した他殖促進機構の構築原理
- Principal Investigator
  
  伊藤寿朗
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Nara Institute of Science and Technology
Regulation of incretin secretion by microbiota metabolites
- Principal Investigator
  
  TSUBOI Takashi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  The University of Tokyo
Longevity control associated with plant reproduction
- Principal Investigator
  
  Ito Toshiro
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  Nara Institute of Science and Technology
植物幹細胞研究を加速させる植物ホルモンの高分解能検出Principal Investigator
- Principal Investigator
  
  北口哲也
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Tokyo Institute of Technology
Molecular mechanisms of gastrointestinal hormone secretion by intestinal bacterial metabolites
- Principal Investigator
  
  TSUBOI Takashi
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  The University of Tokyo
Development of genetically-encoded multi-color biosensors for intracellular signalingPrincipal Investigator
- Principal Investigator
  
  Kitaguchi Tetsuya
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Tokyo Institute of Technology
  Waseda University
Events caused by floral induction-Is there a death hormone?
- Principal Investigator
  
  ITO Toshiro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Plant molecular biology/Plant physiology
- Research Institution
  Nara Institute of Science and Technology
Molecular mechanisms of ghrelin secretion from endocrine cells
- Principal Investigator
  
  TSUBOI Takashi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  The University of Tokyo
Development of genetically-encoded multi-color ATP sensors for clarification of energy metabolism.Principal Investigator
- Principal Investigator
  
  KITAGUCHI TETSUYA
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Waseda University
Functional relationship between reelin signal and layer formation during development of cerebral cortexPrincipal Investigator
- Principal Investigator
  
  KITAGUCHI Tetsuya
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Waseda University
  The Institute of Physical and Chemical Research
Transcriptional regulation of a myeloid-lineage specific gene lysozyme C during zebrafish myelopoiesisPrincipal Investigator
- Principal Investigator
  
  KITAGUCHI Tetsuya
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  The Institute of Physical and Chemical Research

[Book] 図説生物学「神経細胞の構造、様々な形態・シナプスと興奮伝達の制御」2009
- Author(s)
  北口哲也
- Publisher
  東京大学出版会(印刷中)
- Data Source
  KAKENHI-PROJECT-19790149
[Book] 図説生物学「膜電位発生の仕組み・イオンチャネル」2009
- Author(s)
  北口哲也
- Publisher
  東京大学出版会(印刷中)
- Data Source
  KAKENHI-PROJECT-19790149
[Book] 図説生物学「神経細胞の構造、様々な形態・シナプスと興奮伝達の制御」
- Author(s)
  北口哲也
- Publisher
  東京大学出版会(印刷中)
- Data Source
  KAKENHI-PROJECT-19790149
[Book] 図説生物学「膜電位発生の仕組み・イオンチャネル」
- Author(s)
  北口哲也
- Publisher
  東京大学出版会(印刷中)
- Data Source
  KAKENHI-PROJECT-19790149
[Journal Article] F‐actin determines the time‐dependent shift in docking dynamics of glucagon‐like peptide‐1 granules upon stimulation of secretion2023
- Author(s)
  Harada Kazuki、Takashima Maoko、Kitaguchi Tetsuya、Tsuboi Takashi
- Journal Title
  
  FEBS Letters
  
  Volume: 597 Issue: 5 Pages: 657-671
- DOI
  10.1002/1873-3468.14580
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H04121
[Journal Article] Development of a red fluorescent protein-based cGMP indicator applicable for live-cell imaging2022
- Author(s)
  Takizawa Mai、Osuga Yuri、Ishida Rika、Mita Marie、Harada Kazuki、Ueda Hiroshi、Kitaguchi Tetsuya、Tsuboi Takashi
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 833-833
- DOI
  10.1038/s42003-022-03790-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K20659, KAKENHI-PROJECT-20H04121
[Journal Article] Development of red genetically encoded biosensor for visualization of intracellular glucose dynamics2022
- Author(s)
  Mita Marie、Sugawara Izumi、Harada Kazuki、Ito Motoki、Takizawa Mai、Ishida Kentaro、Ueda Hiroshi、Kitaguchi Tetsuya、Tsuboi Takashi
- Journal Title
  
  Cell Chemical Biology
  
  Volume: 29 Issue: 1 Pages: 98-108.e4
- DOI
  10.1016/j.chembiol.2021.06.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K23820, KAKENHI-PUBLICLY-20H04765, KAKENHI-PUBLICLY-20H04836, KAKENHI-PROJECT-18H03851, KAKENHI-PROJECT-20H00575, KAKENHI-PROJECT-20J14411, KAKENHI-PROJECT-20H04121
[Journal Article] Glutamine-induced signaling pathways via amino acid receptors in enteroendocrine L cell lines2020
- Author(s)
  Nakamura Takumi、Harada Kazuki、Kamiya Taichi、Takizawa Mai、K?ppers Jim、Nakajima Kazuo、G?tschow Michael、Kitaguchi Tetsuya、Ohta Kunihiro、Kato Tadafumi、Tsuboi Takashi
- Journal Title
  
  Journal of Molecular Endocrinology
  
  Volume: 64 Issue: 3 Pages: 133-143
- DOI
  10.1530/jme-19-0260
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08529, KAKENHI-PUBLICLY-18H04607, KAKENHI-PROJECT-18J14675, KAKENHI-PROJECT-19J15030
[Journal Article] Green fluorescent protein-based lactate and pyruvate indicators suitable for biochemical assays and live cell imaging.2020
- Author(s)
  Harada K*, Chihara T*, Hayasaka Y*, Mita M, Takizawa M, Ishida K, Arai M, Tsuno S, Matsumoto M, Ishihara T, Ueda H, Kitaguchi T, Tsuboi T. *Equal contribution
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1-11
- DOI
  10.1038/s41598-020-76440-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K23820, KAKENHI-PUBLICLY-20H04765, KAKENHI-PUBLICLY-20H04836, KAKENHI-PROJECT-18H03851, KAKENHI-PROJECT-20H04121, KAKENHI-PROJECT-20J14411, KAKENHI-PROJECT-17K08529, KAKENHI-PROJECT-19H03326, KAKENHI-PROJECT-17H06113
[Journal Article] Green Fluorescent Protein-Based Glucose Indicators Report Glucose Dynamics in Living Cells2019
- Author(s)
  Mita Marie、Ito Motoki、Harada Kazuki、Sugawara Izumi、Ueda Hiroshi、Tsuboi Takashi、Kitaguchi Tetsuya
- Journal Title
  
  Analytical Chemistry
  
  Volume: 91 Issue: 7 Pages: 4821-4830
- DOI
  10.1021/acs.analchem.9b00447
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04832, KAKENHI-PROJECT-16J06838, KAKENHI-PROJECT-16K01922, KAKENHI-PROJECT-18H03851
[Journal Article] RGB-Color Intensiometric Indicators to Visualize Spatiotemporal Dynamics of ATP in Single Cells2018
- Author(s)
  Arai Satoshi、Kriszt R?kus、Harada Kazuki、Looi Liang-Sheng、Matsuda Shogo、Wongso Devina、Suo Satoshi、Ishiura Shoichi、Tseng Yu-Hua、Raghunath Michael、Ito Toshiro、Tsuboi Takashi、Kitaguchi Tetsuya
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 57 Issue: 34 Pages: 10873-10878
- DOI
  10.1002/anie.201804304
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01922, KAKENHI-PROJECT-16K07063, KAKENHI-PROJECT-16J06838, KAKENHI-PROJECT-16H06044
[Journal Article] RGB-Color Intensiometric Indicators to Visualize Spatiotemporal Dynamics of ATP in Single Cells2018
- Author(s)
  Arai Satoshi、Kriszt Rokus、Harada Kazuki、Looi Liang-Sheng、Matsuda Shogo、Wongso Devina、Suo Satoshi、Ishiura Shoichi、Tseng Yu-Hua、Raghunath Michael、Ito Toshiro、Tsuboi Takashi、Kitaguchi Tetsuya
- Journal Title
  
  Angewandte Chemie
  
  Volume: 130 Issue: 34 Pages: 11039-11044
- DOI
  10.1002/ange.201804304
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19342, KAKENHI-PUBLICLY-17H05843, KAKENHI-PUBLICLY-18H04839, KAKENHI-PROJECT-15H02405
[Journal Article] Generation of a cGMP indicator with an expanded dynamic range by optimization of amino acid linkers between a fluorescent protein and PDE5α.2017
- Author(s)
  Matsuda S, Harada K, Ito M, Takizawa M, Wongso D, Tsuboi T, Kitaguchi T
- Journal Title
  
  ACS Sensors
  
  Volume: 2 Issue: 1 Pages: 46-57
- DOI
  10.1021/acssensors.6b00582
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460289, KAKENHI-PROJECT-26291018, KAKENHI-PROJECT-16K01922
[Journal Article] Flashbody: A Next Generation Fluobody with Fluorescence Intensity Enhanced by Antigen Binding2017
- Author(s)
  Wongso Devina、Dong Jinhua、Ueda Hiroshi、Kitaguchi Tetsuya
- Journal Title
  
  Analytical Chemistry
  
  Volume: 89 Issue: 12 Pages: 6719-6725
- DOI
  10.1021/acs.analchem.7b00959
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01922, KAKENHI-PROJECT-15H04191
[Journal Article] 蛍光蛋白質センサーをテーラーメード化2017
- Author(s)
  北口哲也
- Journal Title
  
  日経バイオテク
  
  Volume: 7月24日号 Pages: 42-45
- Data Source
  KAKENHI-PROJECT-16K01922
[Journal Article] Red fluorescent protein-based cAMP indicator applicable to optogenetics and in vivo imaging2017
- Author(s)
  Harada Kazuki、Ito Motoki、Wang Xiaowen、Tanaka Mika、Wongso Devina、Konno Ayumu、Hirai Hirokazu、Hirase Hajime、Tsuboi Takashi、Kitaguchi Tetsuya
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 7351-7351
- DOI
  10.1038/s41598-017-07820-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01922, KAKENHI-PROJECT-15H04254, KAKENHI-PROJECT-16J06838, KAKENHI-PROJECT-26460289, KAKENHI-PROJECT-16K15477, KAKENHI-PROJECT-15K18330
[Journal Article] Lysophosphatidylinositol-induced activation of the cation channel TRPV2 triggers glucagon-like peptide-1 secretion in enteroendocrine L cells2017
- Author(s)
  Kazuki Harada、 Tetsuya Kitaguchi、 Taichi Kamiya、 Kyaw Htet Aung、 Kazuaki Nakamura、 Kunihiro Ohta and Takashi Tsuboi
- Journal Title
  
  J. Biol. Chem
  
  Volume: 292 Issue: 26 Pages: 10855-10864
- DOI
  10.1074/jbc.m117.788653
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291018, KAKENHI-PLANNED-17H06380, KAKENHI-PROJECT-26460289, KAKENHI-PROJECT-17H03711
[Journal Article] 蛍光・発光プローブ2016
- Author(s)
  北口哲也
- Journal Title
  
  光アライアンス
  
  Volume: 27 Pages: 15-19
- Data Source
  KAKENHI-PROJECT-25350970
[Journal Article] Wide and high resolution tension measurement using FRET in embryo.2016
- Author(s)
  Satoshi Yamashita, Takashi Tsuboi, Nanako Ishinabe, Tetsuya Kitaguchi, Tatsuo Michiue
- Journal Title
  
  Scientific Reports
  
  Volume: 該当なし Issue: 1 Pages: 28535-28535
- DOI
  10.1038/srep28535
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15J10195, KAKENHI-PROJECT-26440115, KAKENHI-PROJECT-26460289, KAKENHI-PROJECT-26291018
[Journal Article] 蛍光・発光プローブ2016
- Author(s)
  北口哲也
- Journal Title
  
  光アライアンス
  
  Volume: 27 Pages: 15-19
- Data Source
  KAKENHI-PROJECT-16K01922
[Journal Article] Integrative function of adrenaline receptors for glucagon-like peptide-1 exocytosis in enteroendocrine L cell line GLUTag2015
- Author(s)
  Kazuki Harada, Tetsuya Kitaguchi, Takashi Tsuboi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 印刷中 Issue: 4 Pages: 1053-1058
- DOI
  10.1016/j.bbrc.2015.03.151
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460289, KAKENHI-PROJECT-26291018
[Journal Article] Low glucose-induced ghrelin secretion is mediated by ATP-sensitive potassium channel.2015
- Author(s)
  Manami Oya, Tetsuya Kitaguchi, Kazuki Harada, Rika Numano, Takahiro Sato, Masayasu Kojima and Takashi Tsuboi.
- Journal Title
  
  J Endocrinol
  
  Volume: 226 Issue: 1 Pages: 25-34
- DOI
  10.1530/joe-15-0090
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25350970, KAKENHI-PROJECT-26460289, KAKENHI-PROJECT-26650025, KAKENHI-PROJECT-26291018
[Journal Article] Genetically-encoded yellow fluorescent cAMP indicator with an expanded dynamic range for dual-color imaging.2014
- Author(s)
  Haruki Odaka, Satoshi Arai, Takafumi Inoue and Tetsuya Kitaguchi.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 6 Pages: e100252-e100252
- DOI
  10.1371/journal.pone.0100252
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25350970
[Journal Article] Vesicular nucleotide transporter is involved in ATP storage of secretory lysosomes in astrocytes.2013
- Author(s)
  Manami Oya
- Journal Title
  
  Biochemical Biophysical Research Communications.
  
  Volume: 438 Issue: 1 Pages: 145-151
- DOI
  10.1016/j.bbrc.2013.07.043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J08221, KAKENHI-PROJECT-21671002, KAKENHI-PROJECT-24790207, KAKENHI-PROJECT-25350970
[Journal Article] The small GTPase Cdc42 modulates the number of exocytosis-competent dense-core vesicles in PC12 cells2012
- Author(s)
  Mai Sato, Tetsuya Kitaguchi(co-first), Rika Numano, Kazuya Ikematsu, Masaki Kakeyama, Masayuki Murata, Ken Sato and Takashi Tsuboi.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 420 Pages: 417-421
- Data Source
  KAKENHI-PROJECT-22790197
[Journal Article] The small GTPase Cdc42 modulates the number of exocytosis-competent dense-core vesicles in PC12 cells2012
- Author(s)
  Mai Sato, Tetsuya Kitaguchi (co-first), et al
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790197
[Journal Article] Release of tumor necrosis factor-alpha from macrophages is mediated by small GTPase Rab372011
- Author(s)
  Ryoichi Mori, Kazuya Ikematsu, Tetsuya Kitaguchi, Sang Eun Kim, Momoko Okamoto, Takuya Chiba, Atsushi Miyawaki, Isao Shimokawa and Takashi Tsuboi.
- Journal Title
  
  Eur J Immunol
  
  Volume: 41 Pages: 3230-3239
- Data Source
  KAKENHI-PROJECT-22790197
[Journal Article] Age-dependent preferential dense-core vesicle exocytosis in neuroendocrine cells revealed by newly developed monomeric fluorescent timer protein2010
- Author(s)
  Takashi Tsuboi, Tetsuya Kitaguchi(co-first), Satoshi Karasawa, Mitsunori Fukuda and Atsushi Miyawaki.
- Journal Title
  
  Mol Biol Cell
  
  Volume: 21 Pages: 87-94
- Data Source
  KAKENHI-PROJECT-22790197
[Journal Article] Duration of fusion pore opening and the amount of hormone released are regulated by myosin II during kiss-and-run exocytosis2010
- Author(s)
  Ryo Aoki, Tetsuya Kitaguchi(co-first)
- Journal Title
  
  Biochemical Journal
  
  Volume: 429 Pages: 497-504
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790197
[Journal Article] Duration of fusion pore opening and the amount of hormone released are regulated by myosin II during kiss-and-run exocytosis2010
- Author(s)
  Ryo Aoki, Tetsuya Kitaguchi(co-first), Manami Oya, Yu Yanagihara, Mai Sato, Atsushi Miyawaki and Takashi Tsuboi.
- Journal Title
  
  Biochem J
  
  Volume: 429 Pages: 497-504
- Data Source
  KAKENHI-PROJECT-22790197
[Journal Article] Transcriptional regulation of a myeloid-lineagespecific gene lysozyme C during zebrafish myelopoiesis2009
- Author(s)
  Tetsuya Kitaguchi, Koichi Kawakami and Atsuo Kawahara
- Journal Title
  
  Mech Dev in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790149
[Patent] リガンド蛍光センサータンパク質とその使用2016
- Inventor(s)
  北口哲也、坪井貴司、上田宏、新井敏
- Industrial Property Rights Holder
  北口哲也、坪井貴司、上田宏、新井敏
- Industrial Property Rights Type
  特許
- Filing Date
  2016-12-02
- Overseas
- Data Source
  KAKENHI-PROJECT-16K01922
[Patent] 「リガンド蛍光センサータンパク質とその使用」2016
- Inventor(s)
  北口哲也、坪井貴司、上田宏
- Industrial Property Rights Holder
  北口哲也、坪井貴司、上田宏
- Industrial Property Rights Type
  特許
- Filing Date
  2016-12-02
- Overseas
- Data Source
  KAKENHI-PROJECT-25350970
[Patent] リガンド蛍光センサータンパク質とその使用2016
- Inventor(s)
  北口哲也、坪井貴司、上田宏
- Industrial Property Rights Holder
  北口哲也、坪井貴司、上田宏
- Industrial Property Rights Type
  特許
- Filing Date
  2016-05-24
- Overseas
- Data Source
  KAKENHI-PROJECT-16K01922
[Patent] ATP蛍光センサータンパク質2015
- Inventor(s)
  北口哲也、新井敏、坪井貴司
- Industrial Property Rights Holder
  北口哲也、新井敏、坪井貴司
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-237524
- Filing Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-25350970
[Presentation] 蛍光タンパク質を用いた緑色蛍光輝度変化型乳酸センサーの開発2019
- Author(s)
  千原貴美、三田真理恵、菅原和、相木彩希、早坂優希、原田一貴、上田宏、北口哲也、坪井貴司
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K01922
[Presentation] 蛍光タンパク質を用いた緑色蛍光輝度変化型乳酸センサーの開発2019
- Author(s)
  千原貴美、三田真理恵、菅原和、相木彩希、早坂優希、原田一貴、上田宏、北口哲也、坪井貴司
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04832
[Presentation] 生細胞イメージングを目指した遺伝子コード型ジベレリンプローブの開発2019
- Author(s)
  相原寛史、Yanyan Hou、上田宏、伊藤寿朗、北口哲也
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04832
[Presentation] 生細胞イメージングを目指した遺伝子コード型ジベレリンプローブの開発2019
- Author(s)
  相原寛史、Yanyan Hou、上田宏、伊藤寿朗、北口哲
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K01922
[Presentation] 生細胞内のグルコース動態を検出する遺伝子コード型緑色蛍光センサーの創出2019
- Author(s)
  三田真理恵、伊藤幹、原田一貴、菅原和、上田宏、坪井貴司、北口哲也
- Organizer
  2019年度日本生化学会関東支部例会
- Data Source
  KAKENHI-PUBLICLY-18H04832
[Presentation] 緑色蛍光グルコースセンサーが検出する人工甘味料による膵β細胞のグルコース恒常性攪乱2019
- Author(s)
  三田真理恵、伊藤幹、原田一貴、菅原和、永田怜、芦田翼、上田宏、坪井貴司、北口哲也
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K01922
[Presentation] L-グルタミンによるアミノ酸受容体を介したグルカゴン様ペプチド-1分泌制御機構の解明2019
- Author(s)
  原田一貴, 中村匠, 神谷泰智, 滝澤舞, 中島一夫，北口哲也，太田邦史, 坪井貴司
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08529
[Presentation] 緑色蛍光グルコースセンサーが検出する人工甘味料による膵β細胞のグルコース恒常性攪乱2019
- Author(s)
  三田真理恵、伊藤幹、原田一貴、菅原和、永田怜、芦田翼、上田宏、坪井貴司、北口哲也
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04832
[Presentation] 生細胞内のグルコース動態を検出する遺伝子コード型緑色蛍光センサーの創出2019
- Author(s)
  三田真理恵、伊藤幹、原田一貴、菅原和、上田宏、坪井貴司、北口哲也
- Organizer
  2019年度日本生化学会関東支部例会
- Data Source
  KAKENHI-PROJECT-16K01922
[Presentation] 赤色蛍光グルコースセンサーによる細胞内グルコース動態の可視化2018
- Author(s)
  菅原和、伊藤幹、三田真理恵、上田宏、坪井貴司、北口哲也
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04832
[Presentation] 赤色蛍光グルコースセンサーによる細胞内グルコース動態の可視化2018
- Author(s)
  菅原和、伊藤幹、三田真理恵、上田宏、坪井貴司、北口哲也
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K01922
[Presentation] Single fluorescent protein-based sensors visualize dynamics of glucose by live cell imaging.2018
- Author(s)
  Marie Mita, Motoki Ito, Kazuki Harada, Izumi Sugawara, Hiroshi Ueda, Takashi Tsuboi and Tetsuya Kitaguchi.
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K01922
[Presentation] 赤色蛍光タンパク質を用いたcGMP蛍光センサーの生細胞イメージングへの応用2018
- Author(s)
  石田りか、三田真理恵、原田一貴、上田宏、北口哲也、坪井貴司
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04832
[Presentation] 緑色蛍光タンパク質を用いたピルビン酸センサーの開発2018
- Author(s)
  早坂優希、上田宏、北口哲也、坪井貴司
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04832
[Presentation] Turn-on型の高輝度変化率を有する緑色cAMPセンサーの開発2018
- Author(s)
  相木彩希、上田宏、北口哲也、坪井貴司
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K01922
[Presentation] Single fluorescent protein-based sensors visualize dynamics of glucose by live cell imaging.2018
- Author(s)
  Marie Mita, Motoki Ito, Kazuki Harada, Izumi Sugawara, Hiroshi Ueda, Takashi Tsuboi and Tetsuya Kitaguchi.
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04832
[Presentation] Turn-on型の高輝度変化率を有する緑色cAMPセンサーの開発2018
- Author(s)
  相木彩希、上田宏、北口哲也、坪井貴司
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04832
[Presentation] 緑色蛍光タンパク質を用いたピルビン酸センサーの開発2018
- Author(s)
  早坂優希、上田宏、北口哲也、坪井貴司
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K01922
[Presentation] 抗体を分子認識ドメインとする遺伝子コード型蛍光タンパク質プローブの開発2018
- Author(s)
  相原寛史、Devina Wongso、董金華、上田宏、北口哲也
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04832
[Presentation] 赤色蛍光タンパク質を用いたcGMP蛍光センサーの生細胞イメージングへの応用2018
- Author(s)
  石田りか、三田真理恵、原田一貴、上田宏、北口哲也、坪井貴司
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K01922
[Presentation] 抗体を分子認識ドメインとする遺伝子コード型蛍光タンパク質プローブの開発2018
- Author(s)
  相原寛史、Devina Wongso、董金華、上田宏、北口哲也
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K01922
[Presentation] Hideki Itoh, Satoshi Arai, Thankiah Sudhaharan, Tetsuya Kitaguchi and E. Birgitte Lane. Single-cell quantitative analysis of ATP concentration by fluorescence lifetime imaging microscopy.2017
- Author(s)
  Hideki Itoh, Satoshi Arai, Thankiah Sudhaharan, Tetsuya Kitaguchi and E. Birgitte Lane.
- Organizer
  第55回日本生物物理学会
- Data Source
  KAKENHI-PROJECT-16K01922
[Presentation] Flashbody: genetically-encoded antibody-based fluorescent probe with antigen dependent fluorescence intensity.2017
- Author(s)
  Devina Wongso, Jinhua Dong, Hiroshi Ueda and Tetsuya Kitaguchi.
- Organizer
  第17回蛋白質科学会
- Data Source
  KAKENHI-PROJECT-16K01922
[Presentation] 蛍光タンパク質を用いた単色型グルコース可視化センサーの開発2017
- Author(s)
  三田真理恵、伊藤幹、原田一貴、上田宏、坪井貴司、北口哲也
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K01922
[Presentation] 新規cAMP可視化赤色蛍光タンパク質の開発と応用2017
- Author(s)
  原田一貴，伊藤幹，Xiaowen Wang，田中三佳，Devina Wongso，平瀬肇，坪井貴司，北口哲也
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  オークラアクトシティー浜松（静岡県浜松市）
- Data Source
  KAKENHI-PROJECT-26460289
[Presentation] 赤色蛍光タンパク質を用いたcGMP蛍光センサーの開発2017
- Author(s)
  石田りか、三田真理恵、原田一貴、上田宏、北口哲也、坪井貴司
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K01922
[Presentation] リゾフォスファチジルイノシトールによるグルカゴン様ペプチド-1分泌機構2017
- Author(s)
  原田一貴, 北口哲也, 神谷泰智, Aung Htet Kyaw, 中村和昭, 太田邦史, 坪井貴司
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-26460289
[Presentation] A red fluorescent protein-based cAMP indicator for dual color imaging, optogenetic manipulations and in vivo imaging.2017
- Author(s)
  Kazuki Harada, Motoki Ito, Xiaowen Wang, Mika Tanaka, Devina Wongso, Hajime Hirase, Takashi Tsuboi and Tetsuya Kitaguchi.
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  浜松
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K01922
[Presentation] 小腸内分泌L細胞におけるリソフォスファチジルイノシトール依存性細胞内Ca2+濃度上昇機構2016
- Author(s)
  原田一貴, 北口哲也, 神谷泰智，坪井貴司
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-26460289
[Presentation] 赤色蛍光タンパク質を用いた生体内cAMP可視化プローブの開発2016
- Author(s)
  伊藤幹、原田一貴、Devina Wongso、坪井貴司、北口哲也
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K01922
[Presentation] 蛍光タンパク質を用いた単色型cGMP可視化プローブの開発2016
- Author(s)
  松田翔吾、原田一貴、伊藤幹、滝澤舞、Devina Wongso、坪井貴司、北口哲也
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K01922
[Presentation] 蛍光タンパク質を用いた単色型cGMP可視化プローブの開発2016
- Author(s)
  松田翔吾, 原田一貴, 伊藤幹, 滝澤舞, Devina Wongso, 坪井貴司, 北口哲也
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-26460289
[Presentation] 胃グレリン分泌細胞からのグレリン分泌制御機構の解析2016
- Author(s)
  原田一貴, 北口哲也, 大屋愛実, 沼野利佳, 佐藤貴弘, 児島将康，坪井貴司
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-03-23
- Invited
- Data Source
  KAKENHI-PROJECT-26460289
[Presentation] Spatiotemporal imaging and quantitative analysis of subcellular ATP using RGB-colorful fluorescent protein based indicators.2016
- Author(s)
  Satoshi Arai, Hideki Itoh, Thankiah Sudhaharan, E. Birgitte Lane and Tetsuya Kitaguchi.
- Organizer
  第54回日本生物物理学会
- Place of Presentation
  つくば
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-25350970
[Presentation] 小腸内分泌L細胞株におけるL-グルタミン投与時のGLP-1分泌機構2016
- Author(s)
  神谷泰智，原田一貴, 北口哲也, 坪井貴司
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-26460289
[Presentation] RGBカラーの蛍光ATPセンサーが切り拓くエネルギー代謝研究2016
- Author(s)
  新井敏、伊藤寿朗、坪井貴司、北口哲也
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-25350970
[Presentation] アドレナリンによるインクレチン分泌調節機構の解析2015
- Author(s)
  原田一貴、北口哲也、坪井貴司
- Organizer
  第92回日本生理学会大会
- Place of Presentation
  神戸国際会議場展示場（兵庫県神戸市）
- Year and Date
  2015-03-22
- Data Source
  KAKENHI-PROJECT-26460289
[Presentation] Visualization of subcellular ATP dynamics in Arabiodopsis protoplasts with an intensiometric fluorescent protein-based indicator.2015
- Author(s)
  Satoshi Arai, Liang-Sheng Looi, Wan-Yi Wee, Toshiro Ito and Tetsuya Kitaguchi.
- Organizer
  第３８回分子生物学会
- Place of Presentation
  兵庫県神戸市　神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25350970
[Presentation] Vesicular nucleotide transporter regulates ATP storage in secretory lysosome in astrocyte.2014
- Author(s)
  Takashi Tsuboi, Manami Oya and Tetsuya Kitaguchi.
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-25350970
[Presentation] アドレナリンによる小腸内分泌L細胞からのGLP-1分泌への影響2014
- Author(s)
  原田一貴、北口哲也、坪井貴司
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-26460289
[Presentation] タンパク質の構造変化を光情報に変換するバイオセンサーの創出2013
- Author(s)
  新井敏、北口哲也
- Organizer
  第62回高分子討論会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-25350970
[Presentation] Development of intensiometric fluorescent indicators for sensing the dynamics of intracellular ATP.2013
- Author(s)
  Satoshi Arai, Manami Oya, Takashi Tsuboi and Tetsuya Kitaguchi.
- Organizer
  第36回分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25350970
[Presentation] 神経内分泌細胞における優先的開口放出制御機構の解析2011
- Author(s)
  坪井貴司、北口哲也、唐澤智司、福田光則、宮脇敦史
- Organizer
  第88回日本生理学会大会・第116回日本解剖学会総会・全国学術集会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22790197
[Presentation] ミオシン2は表層繊維状アクチンの再編成を介して融合孔の開いている時間を制御する2010
- Author(s)
  青木亮、北口哲也、宮脇敦史、坪井貴司
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-22790197
[Presentation] 産生時間依存的な開口放出機構の解析2010
- Author(s)
  坪井貴司、北口哲也、唐澤智司、福田光則、宮脇敦史
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-22790197
[Presentation] ゼブラフィッシュの一次造血におけるミエロイド系細胞の発生機構2006
- Author(s)
  北口哲也、川原敦雄
- Organizer
  第12回小型魚類研究会
- Place of Presentation
  三島
- Data Source
  KAKENHI-PROJECT-19790149
[Presentation] An intensiometric fluorescent protein-based indicator visualizes ATP dynamics in intracellular compartments.
- Author(s)
  Satoshi Arai, Rokus Gyorgy Kriszt, Michael Raghunath and Tetsuya Kitaguchi.
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25350970
[Presentation] Improvement of genetically-encoded yellow fluorescent cAMP indicator for dual-color imaging.
- Author(s)
  Haruki Odaka, Satoshi Arai, Takafumi Inoue and Tetsuya Kitaguchi.
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25350970

1. TSUBOI Takashi (80415231)

# of Collaborated Projects: 7 results

# of Collaborated Products: 33 results
2. ITO Toshiro (90517096)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. 原田一貴 (60830734)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. OHTA Kunihiro (90211789)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 新井敏 (70454056)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
6. 上田宏 (60232758)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
7. 朱博 (70886605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 鈴木団 (40350475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 三田真理恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kitaguchi Tetsuya 北口 哲也

KITAGUCHI TETSUYA 北口 哲也

KITAGUCHI Tetsuya 北口 哲也

Research Projects

Research Products

Co-Researchers

機械学習を活用したユニバーサルな基盤構造創出による蛍光免疫センサーの迅速開発Principal Investigator

Principal Investigator

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腸内細菌代謝物による認知的柔軟性制御における消化管ホルモンを介した分子機構の解析

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両性花における動物を利用した他殖促進機構の構築原理

Principal Investigator

Project Period (FY)

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Review Section

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Regulation of incretin secretion by microbiota metabolites

Principal Investigator

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Review Section

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Longevity control associated with plant reproduction

Principal Investigator

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植物幹細胞研究を加速させる植物ホルモンの高分解能検出Principal Investigator

Principal Investigator

Project Period (FY)

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Molecular mechanisms of gastrointestinal hormone secretion by intestinal bacterial metabolites

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Development of genetically-encoded multi-color biosensors for intracellular signalingPrincipal Investigator

Principal Investigator

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Events caused by floral induction-Is there a death hormone?

Principal Investigator

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Molecular mechanisms of ghrelin secretion from endocrine cells

Principal Investigator

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Development of genetically-encoded multi-color ATP sensors for clarification of energy metabolism.Principal Investigator

Principal Investigator

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Functional relationship between reelin signal and layer formation during development of cerebral cortexPrincipal Investigator

Principal Investigator

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Transcriptional regulation of a myeloid-lineage specific gene lysozyme C during zebrafish myelopoiesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Kitaguchi Tetsuya 北口哲也

KITAGUCHI TETSUYA 北口哲也

KITAGUCHI Tetsuya 北口哲也