Kubota Akira 久保田彰

Researcher Number	60432811
Other IDs	https://orcid.org/0000-0003-1159-9031
Affiliation (Current)	2025: 帯広畜産大学, 畜産学部, 教授
Affiliation (based on the past Project Information) *help	2023 – 2025: 帯広畜産大学, 畜産学部, 教授 2014 – 2022: 帯広畜産大学, 畜産学部, 准教授
Review Section/Research Field	Principal Investigator Basic Section 63030:Chemical substance influence on environment-related / Risk sciences of radiation and chemicals / Medium-sized Section 64:Environmental conservation measure and related fields Except Principal Investigator Medium-sized Section 64:Environmental conservation measure and related fields / Medium-sized Section 63:Environmental analyses and evaluation and related fields / Basic Section 64010:Environmental load and risk assessment-related / Basic Section 49050:Bacteriology-related / Risk sciences of radiation and chemicals
Keywords	Principal Investigator ゼブラフィッシュ / 環境汚染物質 / 発生毒性 / 環境化学物質 / CYP / 化学物質 / リン酸エステル系難燃剤 / シトクロムP450 / 内分泌撹乱 / 細胞内受容体 … More / 薬物動態 / 薬物感受性 / アゾール系抗真菌薬 / 薬物相互作用 / 薬物代謝 / タンチョウ / 希少鳥類 / 神経伝達物質 / 脂質メディエーター / 神経発生毒性 / 心血管毒性 / ネオニコチノイド系殺虫剤 / ダイオキシン / 抗エストロゲン作用 / 甲状腺ホルモン撹乱 / 拮抗作用 / 複合影響 / 環境エストロゲン / 毒性発現機序 / 統合オミクス / 環境毒性 / in vivo ハイコンテンツイメージング / AOP / 作用機序 / 発達神経毒性 / 毒性発現機構 / in silico解析 / ビスフェノール類 / エストロゲン受容体 / トキシコロジー / PCB / シグナル伝達 / クロストーク / シトクロムP450 (CYP) / AHR / PXR … More Except Principal Investigator PFAS / 残留性有機汚染物質 / 有機フッ素化合物 / オミクス / 神経伝達物質 / 発生毒性 / 魚類 / PPCPs / リスク評価 / 時空間トレンド / 毒性評価 / 環境動態 / 大阪湾 / 水銀 / 生態リスク / 新興化学物質 / 核内受容体 / 毒性影響 / 環境汚染 / 排泄速度定数 / 取込速度定数 / 医薬品 / イオン性環境汚染物質 / 生物濃縮係数 / タンパク結合 / in vivo曝露試験 / 脳移行 / 中枢神経毒性 / FPMモデル / イオン性の環境汚染物質 / 鉄獲得 / Aspergillus fumigatus / 金属イオン / ガリウムイオン / シデロフォア / 有害金属イオン / トリアセチルフサリニンC / アスペルギルス・フミガツス / 生物濃縮 / 水圏生物 / 新規環境汚染物質 / 化学物質感受性決定帰国 / 発達神経毒性試験ｎ / バイオマーカー / 化学物質感受性決定機構 / 発達神経毒性試験 / mlAOPコンセプト / ネオニコチノイド / ホモロジーモデル / シトクロムP450 / エクスポゾーム / メタボローム / 受容体 / トランスクリプトーム / プロテオーム / オミックス / 種差 / 感受性 / 細胞内受容体 / 化学物質 / 多元的オミックス Less

Distribution, Behavior, and Bioaccumulation of Emerging PFAS in Osaka Bay
- Principal Investigator
  
  田上瑠美
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 64010:Environmental load and risk assessment-related
- Research Institution
  Ehime University
Search for novel, unregulated PPCPs with fish developmental and CNS toxicity
- Principal Investigator
  
  野見山桂
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 64:Environmental conservation measure and related fields
- Research Institution
  Ehime University
Spatiotemporal trend analysis and ecological risk assessment of monitoring and emerging environmental chemicals in the Asia-Pacific region
- Principal Investigator
  
  国末達也
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 64:Environmental conservation measure and related fields
- Research Institution
  Ehime University
Development and clinical application of a non-invasive drug sensitivity assessment method for ex situ conservation of threatened avian speciesPrincipal Investigator
- Principal Investigator
  
  久保田彰
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 64:Environmental conservation measure and related fields
- Research Institution
  Obihiro University of Agriculture and Veterinary Medicine
Whole embryo screening and integrated omics approach using zebrafish for unraveling mechanisms underlying chemical toxicitiesPrincipal Investigator
- Principal Investigator
  
  久保田彰
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63030:Chemical substance influence on environment-related
- Research Institution
  Obihiro University of Agriculture and Veterinary Medicine
New Functions Other Than Iron Ion Acquisition Revealed in Triacetylphsalinin C
- Principal Investigator
  
  Toyotome Takahito
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Obihiro University of Agriculture and Veterinary Medicine
Development of risk assessment method and present of brain transfer by ionic environmental contaminants using fish as an indicator
- Principal Investigator
  
  Nomiyama Kei
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 64:Environmental conservation measure and related fields
- Research Institution
  Ehime University
Elucidation of environmental contamination status and bioaccumulation features of emerging perfluoroalkyl substances (PFASs) and assessment of their ecotoxicological effects
- Principal Investigator
  
  石橋弘志
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 63:Environmental analyses and evaluation and related fields
- Research Institution
  Ehime University
Biomagnification mechanism, spatiotemporal trend, and risk assessment of legacy and new environmental pollutants in various aquatic animal species
- Principal Investigator
  
  Kunisue Tatsuya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 64:Environmental conservation measure and related fields
- Research Institution
  Ehime University
Assessment of developmental toxicities caused by chemical substances and elucidation of their mechanisms based on the quantitative phenotype screening using small fishPrincipal Investigator
- Principal Investigator
  
  Kubota Akira
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63030:Chemical substance influence on environment-related
- Research Institution
  Obihiro University of Agriculture and Veterinary Medicine
Evaluation of Chemical Susceptibility Diversity by mlAOP Concept and its Application to Understanding Insecticide Poisoning
- Principal Investigator
  
  IKENAKA Yoshinori
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 63:Environmental analyses and evaluation and related fields
- Research Institution
  Hokkaido University
Understanding of molecular mechanisms of chemically-induced toxicities and risk evaluation using zebrafishPrincipal Investigator
- Principal Investigator
  
  Kubota Akira
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Obihiro University of Agriculture and Veterinary Medicine
Multiple Omics Analysis to Understand the Species Differences in Chemical-intracellular Receptor Signaling Disruption
- Principal Investigator
  
  IWATA Hisato
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Ehime University
魚類の核内受容体PXRシグナル経路の撹乱に関わる新規分子機構とその毒性学的意義Principal Investigator
- Principal Investigator
  
  久保田彰
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Obihiro University of Agriculture and Veterinary Medicine

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014

All Journal Article Presentation

[Journal Article] Assessment of developmental toxicity and the potential mode of action underlying single and binary exposure to estrogenic endocrine disrupting chemicals in zebrafish (Danio rerio)2024
- Author(s)
  Ahmed Rehab Youssef Salama, Tanoue Rumi, Chen Xing, Kawai Yusuke K., Kubota Akira
- Journal Title
  
  Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
  
  Volume: 277 Pages: 109821-109821
- DOI
  10.1016/j.cbpc.2023.109821
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22KJ0144, KAKENHI-PROJECT-23K25000
[Journal Article] In vivo and in silico assessments of estrogenic potencies of bisphenol A and its analogs in zebrafish (Danio rerio): Validity of in silico approaches to predict in vivo effects2023
- Author(s)
  Kubota Akira、Hirano Masashi、Yoshinouchi Yuka、Chen Xing、Nakamura Michiko、Wakayama Yumi、Lee Jae Seung、Nakata Haruhiko、Iwata Hisato、Kawai Yusuke K.
- Journal Title
  
  Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
  
  Volume: 269 Pages: 109619-109619
- DOI
  10.1016/j.cbpc.2023.109619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22KJ0144, KAKENHI-PROJECT-23K25000, KAKENHI-PROJECT-23K27045
[Journal Article] fficient in vivo and in silico assessments of antiandrogenic potential in zebrafish2023
- Author(s)
  Xing Chen, Masashi Hirano, Hiroshi Ishibashi, Jae Seung Lee, Yusuke K Kawai, Akira Kubota
- Journal Title
  
  Comparative Biochemistry and Physiology Part C
  
  Volume: 264 Pages: 109513-109513
- DOI
  10.1016/j.cbpc.2022.109513
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H00634, KAKENHI-PROJECT-22KJ0144, KAKENHI-PROJECT-23K25000
[Journal Article] ゼブラフィッシュを用いたネオニコチノイド系農薬の体内動態と発達神経毒性の解明2022
- Author(s)
  池本秀樹, 沖澤優花, 川合佑典, 一瀬貴大, 池中良徳, 久保田彰
- Journal Title
  
  環境ホルモン学会ニュースレター
  
  Volume: 24(4) Pages: 3-4
- Data Source
  KAKENHI-PROJECT-19H04275
[Journal Article] Mechanistic investigation of developmental cardiovascular toxicity caused by organophosphate triesters and their metabolites in zebrafish embryo2022
- Author(s)
  Lee Jae Seung, Kawai K Yusuke, Morita Yuri, Covaci Adrian, Kubota Akira
- Journal Title
  
  環境ホルモン学会ニュースレター
  
  Volume: 24(3) Pages: 4-4
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04275
[Journal Article] 「北海道における毒性学研究」および「受容体原性毒性に関する研究の最前線」の趣旨および概要説明2022
- Author(s)
  久保田彰
- Journal Title
  
  環境ホルモン学会ニュースレター
  
  Volume: 24(3) Pages: 5-5
- Data Source
  KAKENHI-PROJECT-19H04275
[Journal Article] Estrogenic and growth inhibitory responses to organophosphorus flame retardant metabolites in zebrafish embryos2022
- Author(s)
  Lee Jae Seung, Kawai K Yusuke, Morita Yuri, Covaci Adrian, Kubota Akira
- Journal Title
  
  Comparative Biochemistry and Physiology, Part C
  
  Volume: 256 Pages: 109321-109321
- DOI
  10.1016/j.cbpc.2022.109321
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04275
[Journal Article] In vivo and in silico analyses of estrogenic potential of equine estrogens in medaka (Oryzias latipes)2021
- Author(s)
  Hiroshi Ishibashi, Masaya Uchida, Masashi Hirano, Taka Hayashi, Ryoko Yamamoto, Akira Kubota, Nobuhiro Ichikawa, Yasuhiro Ishibashi, Nobuaki Tominaga, Koji Arizono
- Journal Title
  
  Science of the Total Environment
  
  Volume: 767 Pages: 1443792-1443792
- DOI
  10.1016/j.scitotenv.2020.144379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H04275, KAKENHI-PROJECT-19H04286
[Journal Article] Hepatic transcriptional profile and tissue distribution of cytochrome P450 1-3 genes in the red-crowned crane Grus japonensis2020
- Author(s)
  Kawai Yusuke K.、Itou Kiwamu、Yoshino Tomoo、Iima Hiroko、Matsumoto Fumio、Kubota Akira
- Journal Title
  
  Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
  
  Volume: 228 Pages: 108643-108643
- DOI
  10.1016/j.cbpc.2019.108643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H04275
[Journal Article] Developmental circulatory failure caused by metabolites of organophosphorus flame retardants in zebrafish, Danio rerio2020
- Author(s)
  Jae Seung Lee, Yuri Morita, Yusuke K. Kawai, Adrian Covaci, Akira Kubota
- Journal Title
  
  Chemosphere
  
  Volume: 246 Pages: 125738-125738
- DOI
  10.1016/j.chemosphere.2019.125738
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04275
[Journal Article] Transcriptional profiling of cytochrome P450 genes in the liver of adult zebrafish, <i>Danio rerio</i>2019
- Author(s)
  Akira Kubota, Yusuke K. Kawai, Natsumi Yamashita, Jae Seung Lee, Daisuke Kondoh, Shuangyi Zhang, Yasunobu Nishi, Kazuyuki Suzuki, Takio Kitazawa, Hiroki Teraoka
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 44 Issue: 5 Pages: 347-356
- DOI
  10.2131/jts.44.347
- NAID
  130007642915
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05334, KAKENHI-PROJECT-19H04275
[Journal Article] The evolution of UDP-glycosyl/glucuronosyltransferase 1E (UGT1E) genes in bird lineages is linked to feeding habits but UGT2 genes is not.2018
- Author(s)
  Yusuke K. Kawai, Yoshinori Ikenaka, Mayumi Ishizuka, Akira Kubota
- Journal Title
  
  PLoS One
  
  Volume: 13 Issue: 10 Pages: 1-13
- DOI
  10.1371/journal.pone.0205266
- NAID
  120006540774
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26220103, KAKENHI-PROJECT-18H04132, KAKENHI-PROJECT-15H05334, KAKENHI-PROJECT-17K20038
[Journal Article] 十勝の台風被害による飼料用トウモロコシサイレージおよび牧草サイレージのかび毒汚染の実態2018
- Author(s)
  川島千帆, 久保田　彰
- Journal Title
  
  北海道畜産草地学会報
  
  Volume: 6 Pages: 29-33
- NAID
  40021519058
- Data Source
  KAKENHI-PROJECT-26220103
[Journal Article] 十勝の台風被害による飼料用トウモロコシサイレージおよび牧草サイレージのかび毒汚染の実態2018
- Author(s)
  川島千帆、久保田彰
- Journal Title
  
  北海道畜産草地学会報
  
  Volume: 6 Pages: 29-34
- NAID
  40021519058
- Data Source
  KAKENHI-PROJECT-15H05334
[Journal Article] Characterization and imaging of lead distribution in bones of lead-exposed birds by ICP-MS and LA-ICP-MS2018
- Author(s)
  Ishii Chihiro、Nakayama Shouta M.M.、Kataba Andrew、Ikenaka Yoshinori、Saito Keisuke、Watanabe Yukiko、Makino Yoshiki、Matsukawa Takehisa、Kubota Ayano、Yokoyama Kazuhito、Mizukawa Hazuki、Hirata Takafumi、Ishizuka Mayumi
- Journal Title
  
  Chemosphere
  
  Volume: 212 Pages: 994-1001
- DOI
  10.1016/j.chemosphere.2018.08.149
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0009, KAKENHI-PROJECT-18H04132, KAKENHI-PROJECT-26247094
[Journal Article] Dexamethasone-induced hepatomegaly and steatosis in larval zebrafish2017
- Author(s)
  Guojun Yin, Liping Cao, Jinliang Du, Rui Jia, Takio Kitazawa, Akira Kubota, Hiroki Teraoka
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 42 Issue: 4 Pages: 455-459
- DOI
  10.2131/jts.42.455
- NAID
  130005765960
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05334
[Journal Article] Dexamethasone-induced hepatomegaly and steatosis in larval zebrafish2017
- Author(s)
  Yin G, Cao L, Du J, Jia R, Kitazawa T, Kubota A, Teraoka H.
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 42 Pages: 455-459
- NAID
  130005765960
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220103
[Journal Article] Ecotoxicology of Dioxins in Wild Avian Species2017
- Author(s)
  久保田　彰
- Journal Title
  
  Japanese Journal of Zoo and Wildlife Medicine
  
  Volume: 22 Issue: 4 Pages: 63-67
- DOI
  10.5686/jjzwm.22.63
- NAID
  130006731441
- ISSN
  1342-6133, 2185-744X
- Year and Date
  2017-12-22
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05334
[Journal Article] 野生鳥類におけるダイオキシン類のエコトキシコロジー2017
- Author(s)
  久保田　彰
- Journal Title
  
  日本野生動物医学会誌
  
  Volume: 22 Pages: 63-67
- NAID
  130006731441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26220103
[Journal Article] Organohalogen compounds in pet dog and cat: Do pets biotransform natural brominated products in food to harmful hydroxlated substances?2016
- Author(s)
  Mizukawa H, Nomiyama K, Nakatsu S, Iwata H, Yoo J, Kubota A, Yamamoto M, Ishizuka M, Ikenaka Y, Nakayama M.M.S, Kunisue T, Tanabe S
- Journal Title
  
  Environmental Science & Technology
  
  Volume: 50 Issue: 1 Pages: 444-452
- DOI
  10.1021/acs.est.5b04216
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K16132, KAKENHI-PROJECT-26220103, KAKENHI-PROJECT-25241013, KAKENHI-PROJECT-25660228, KAKENHI-PROJECT-25281050, KAKENHI-PROJECT-25701014, KAKENHI-PROJECT-16H01779, KAKENHI-PROJECT-15H02825, KAKENHI-PROJECT-26304043
[Journal Article] Protective effect of prostacyclin against pre-cardiac edema caused by 2,3,7,8-tetrachlorodibenzo-p-dioxin and a thromboxane receptor agonist in developing zebrafish2016
- Author(s)
  Nijoukubo, D., Tanaka, Y., Okuno, Y., Yin, G., Kitazawa, T., Peterson, R. E., Kubota, A. and Teraoka, H.
- Journal Title
  
  Chemosphere
  
  Volume: 156 Pages: 111-117
- DOI
  10.1016/j.chemosphere.2016.04.107
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220103, KAKENHI-PROJECT-15H05334, KAKENHI-PROJECT-26440169
[Journal Article] Cytochrome P450 20A1 in zebrafish: Cloning, regulation and potential involvement in hyperactivity disorders2016
- Author(s)
  Benjamin Lemaire, Akira Kubota, Conor M. O'Meara, David C. Lamb, Robert L. Tanguay, Jared V. Goldstone, John J. Stegeman
- Journal Title
  
  Toxicology and Applied Pharmacology
  
  Volume: 296 Pages: 73-84
- DOI
  10.1016/j.taap.2016.02.001
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05334, KAKENHI-PROJECT-26220103
[Journal Article] Biological effects of 6-formylindolo[3,2-b]carbazole (FICZ) in vivo are enhanced by loss of CYP1A function in an Ahr2-dependent manner2016
- Author(s)
  Wincent, E., Kubota, A., Timme-Laragy, A. R., Jönsson, M. E., Hahn, M. E. and Stegeman, J. J.
- Journal Title
  
  Biochemical Pharmacology
  
  Volume: 110-111 Pages: 117-129
- DOI
  10.1016/j.bcp.2016.04.012
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220103, KAKENHI-PROJECT-15H05334
[Journal Article] Functional characterization of zebrafish cytochrome P450 1 family proteins expressed in yeast2015
- Author(s)
  Stegeman, J. J., Behrendt, L., Woodin, B. R., Kubota, A., Lemaire, B., Pompon, E., Goldstone, J. V. and Urban, P.
- Journal Title
  
  Biochimica et Biophysica Acta
  
  Volume: 1850(11) Issue: 11 Pages: 2340-2352
- DOI
  10.1016/j.bbagen.2015.07.010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220103, KAKENHI-PROJECT-15H05334
[Journal Article] Enzymatic characterization of in vitro-expressed Baikal seal cytochrome P450 (CYP) 1A1, 1A2, and 1B1: Implication of low metabolic potential of CYP1A2 uniquely evolved in aquatic mammals2015
- Author(s)
  Iwata H, Yamaguchi K, Takeshita Y, Kubota A, Hirakawa S, Isobe T, Hirano M, Kim EY.
- Journal Title
  
  Aquat Toxicol
  
  Volume: 162 Pages: 138-151
- DOI
  10.1016/j.aquatox.2015.03.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J09538, KAKENHI-PROJECT-25660228, KAKENHI-PROJECT-26220103, KAKENHI-PROJECT-26750067, KAKENHI-PROJECT-26881001, KAKENHI-PROJECT-25281008
[Journal Article] Role of pregnane X receptor and aryl hydrocarbon receptor in transcriptional regulation of pxr, CYP2, and CYP3 genes in developing zebrafish.2015
- Author(s)
  Kubota, A., Goldstone, J.V., Lemaire, B., Takata, M., Woodin, B.R., Stegeman, J.J.
- Journal Title
  
  Toxicological Sciences
  
  Volume: 143 Issue: 2 Pages: 398-407
- DOI
  10.1093/toxsci/kfu240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26220103, KAKENHI-PROJECT-26881001
[Journal Article] Involvement of COX2-thromboxane pathway in TCDD-induced precardiac edema in developing zebrafish2014
- Author(s)
  Teraoka H, Okuno Y, Nijoukubo D, Yamakoshi A, Peterson R, Stegeman JJ, Kitazawa T, Hiraga T. and Kubota A.
- Journal Title
  
  Auat Toxicol.
  
  Volume: 154 Pages: 19-26
- DOI
  10.1016/j.aquatox.2014.04.025
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24580462, KAKENHI-PROJECT-26220103, KAKENHI-PROJECT-26440169, KAKENHI-PROJECT-26881001
[Presentation] Assessment of estrogenic effects of endocrine disrupting chemicals through estrogen receptors in animal models2024
- Author(s)
  Rehab YS. Ahmed, Dave Arthur Robledoc, Hisato Iwata, Masashi Hirano, Rumi Tanoue, Yusuke K. Kawai, Akira Kubota
- Organizer
  The 10th Copenhagen Workshop on Endocrine Disrupters
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] In vivo assessment and in silico prediction of estrogenic potency of endocrine disrupting chemicals using zebrafish (Danio rerio)2024
- Author(s)
  Akira Kubota, Masashi Hirano, Yuka Yoshinouchi, Hisato Iwata, Yusuke Kawai
- Organizer
  Pure and Applied Chemistry International Conference 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] Assessment of estrogenic potency and the potential mode of action underlying single and binary exposure to estrogenic endocrine disrupting chemicals in zebrafish (Danio rerio)2024
- Author(s)
  Akira Kubota, Rehab YS. Ahmed, Rumi Tanoue, Masashi Hirano, Yusuke K. Kawai
- Organizer
  SOT 63rd Annual Meeting and ToxExpo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] In vivo and in silico assessments of anti-androgenic and anti-estrogenic potentials of BPA and its analogs using zebrafish2023
- Author(s)
  Xing Chen, Masashi Hirano, Yusuke Kawai, Akira Kubota
- Organizer
  SETAC North America 44th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] In vivo and in silico assessment of estrogenic potency of endocrine disrupting chemicals using zebrafish (Danio rerio)2023
- Author(s)
  Akira Kubota, Masashi Hirano, Yuka Yoshinouchi, Hisato Iwata, Yusuke Kawai
- Organizer
  The international joint meeting of the 23rd International Conference on Cytochrome P450 (ICCP450) and the 38th Annual Meeting of the Japanese Society for the Study of Xenobiotics (JSSX)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] ゼブラフィッシュ胚を用いた抗精神病剤ハロペリドールの発生・神経毒性および生物濃縮性の評価2023
- Author(s)
  水原奈々;田上瑠美;久保田彰;小椋響子;国末達也;野見山桂
- Organizer
  第2回環境化学物質3学会合同大会
- Data Source
  KAKENHI-PROJECT-20H00645
[Presentation] Phenotypic and transcriptomic effects of organophosphorus flame retardants and their metabolites in developing zebrafish2023
- Author(s)
  Jae Seung Lee, Yusuke Kawai, Yuri Morita, Adrian Covaci, Akira Kubota
- Organizer
  第50回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] Biological effects of 2,3,7,8-substituted and non-2,3,7,8-substituted polybrominated dibenzo-p-dioxins in developing zebrafish2023
- Author(s)
  Jae Seung Lee・Xing Chen・Wataru Ishihara・Akitoshi Goto・Tatsuya Kunisue・Yusuke Kawai・Akira Kubota
- Organizer
  第2回環境化学物質３学会合同大会
- Data Source
  KAKENHI-PROJECT-23H00533
[Presentation] 獣医系大学における毒性学教育2023
- Author(s)
  久保田彰
- Organizer
  第50回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] ssessment of developmental toxicity and the mechanistic pathway underlying single and binary exposure to estrogenic endocrine disruptive chemicals in zebrafish2023
- Author(s)
  Ahmed, R., Kawai, Y.K., Tanoue, R. and Kubota, A.
- Organizer
  SOT 62nd Annual Meeting & ToxExpo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] 抗精神病剤ハロペリドールと抗ヒスタミン剤クロルフェニラミンの２種におけるゼブラフィッシュ胚への生物濃縮性比較2023
- Author(s)
  水原奈々・田上瑠美・久保田彰・小椋響子・国末達也・野見山桂
- Organizer
  第2回環境化学物質３学会合同大会
- Data Source
  KAKENHI-PROJECT-23H00533
[Presentation] 医薬品類およびパーソナルケア製品由来物質の生物移行・残留性と中枢神経系への影響の評価2023
- Author(s)
  田上瑠美・甲斐奏・小椋響子・水原奈々・久保田彰・仲山慶・小林淳・国末達也・野見山桂
- Organizer
  第2回環境化学物質３学会合同大会
- Data Source
  KAKENHI-PROJECT-23H00533
[Presentation] 抗精神病剤ハロペリドールと抗ヒスタミン剤クロルフェニラミンの2 種におけるゼブラフィッシュ胚への生物濃縮性比較2023
- Author(s)
  水原奈々;田上瑠美;久保田彰;小椋響子;国末達也;野見山桂
- Organizer
  第2回環境化学物質3学会合同大会
- Data Source
  KAKENHI-PROJECT-20H00645
[Presentation] 分析化学的手法の活用によるゼブラフィッシュ胚を用いた発生毒性評価と毒性発現機構の解析2023
- Author(s)
  久保田彰，Ahmed Rehab，Chen Xing，Lee Jae Seung，池本秀樹，小椋響子，田上瑠美，野見山桂，高橋真，石橋弘志，後藤哲智，国末達也，中村達朗，村田幸久，寺岡宏樹，池中良徳
- Organizer
  第2回環境化学物質3学会合同大会
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] Developmental toxicity and gene expression changes posed by perfluoroalkyl substances in zebrafish2023
- Author(s)
  Akira Kubota, Jae Seung Lee, Kentaro Matsumoto, Hiroshi Ishibashi, Yusuke Kawai
- Organizer
  6th Chemical Hazard Symposium
- Data Source
  KAKENHI-PROJECT-20H00634
[Presentation] Developmental effects of 2,3,7,8-substituted and non-2,3,7,8-substituted polybrominated dibenzo-p-dioxins in zebrafish2023
- Author(s)
  Akira Kubota, Jae Seung Lee, Wataru Ishihara, Xing Chen, Akitoshi Goto, Tatsuya Kunisue, Yusuke Kawai
- Organizer
  The 43rd International Symposium on Halogenated Persistent Organic Pollutants
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] 医薬品類およびパーソナルケア製品由来物質の生物移行・残留性と中枢神経系への影響の評価2023
- Author(s)
  田上瑠美，甲斐奏，小椋響子，水原奈々，久保田彰，仲山慶，小林淳，国末達也，野見山桂
- Organizer
  第2回環境化学物質3学会合同大会
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] In vivo and in silico assessment of antiandrogenic potentials for environmental chemicals using zebrafish2023
- Author(s)
  Chen, X., Hirano, M., Ishibashi, H., Lee, J.S., Kawai, Y.K. and Kubota, A.
- Organizer
  SOT 62nd Annual Meeting & ToxExpo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] 分析化学的手法の活用によるゼブラフィッシュ胚を用いた発生毒性評価と毒性発現機構の解析2023
- Author(s)
  久保田彰;Ahmed Rehab;Chen Xing;Lee Jae Seung;池本秀樹;小椋響子;田上瑠美;野見山桂;高橋真;石橋弘志;後藤哲智;国末達也;中村;達朗;村田幸久;寺岡宏樹;池中良徳
- Organizer
  第2回環境化学物質3学会合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00645
[Presentation] Assessment of toxicokinetics and developmental neurotoxicity of neonicotinoid insecticides in zebrafish2023
- Author(s)
  Akira Kubota, Hideki Ikemoto, Yuka Okizawa, Kyoko Ogura, Nana Mizuhara, Rumi Tanoue, Kei Nomiyama, Yoshinori Ikenaka, Yusuke K. Kawai
- Organizer
  7th Chemical Hazard Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] 分析化学的手法の活用によるゼブラフィッシュ胚を用いた発生毒性評価と毒性発現機構の解析2023
- Author(s)
  久保田彰・Ahmed Rehab・Chen Xing・Lee Jae Seung・池本秀樹・小椋響子・田上瑠美・野見山桂・高橋真・石橋弘志・後藤哲智・国末達也・中村達朗・村田幸久・寺岡宏樹・池中良徳
- Organizer
  第2回環境化学物質3学会合同大会
- Data Source
  KAKENHI-PROJECT-20H00634
[Presentation] 分析化学的手法の活用によるゼブラフィッシュ胚を用いた発生毒性評価と毒性発現機構の解析2023
- Author(s)
  久保田彰・Ahmed Rehab・Chen Xing・Lee Jae Seung・池本秀樹・小椋響子・田上瑠美・野見山桂・高橋真・石橋弘志・後藤哲智・国末達也・中村達朗・村田幸久・寺岡宏樹・池中良徳
- Organizer
  第2回環境化学物質３学会合同大会
- Data Source
  KAKENHI-PROJECT-23H00533
[Presentation] 医薬品類およびパーソナルケア製品由来物質の生物移行・残留性と中枢神経系への影響の評価2023
- Author(s)
  田上瑠美;甲斐奏;小椋響子;水原奈々;久保田彰;仲山慶;小林淳;国末達也;野見山桂
- Organizer
  第2回環境化学物質3学会合同大会
- Data Source
  KAKENHI-PROJECT-20H00645
[Presentation] ゼブラフィッシュ胚を用いた抗精神病薬ハロペリドールの中枢神経系への影響評価2022
- Author(s)
  小椋響子、田上瑠美、久保田彰、国末達也、野見山桂
- Organizer
  4th Chemical Hazard Symposium in Online
- Data Source
  KAKENHI-PROJECT-20H00645
[Presentation] 抗精神病薬ハロペリドール曝露によるゼブラフィッシュ稚魚中神経伝達物質レベルの変化2022
- Author(s)
  小椋響子 , 田上瑠美 , 久保田彰 , 水原奈々 , 池中良徳 , 寺岡宏樹 , 国末達也 , 野見山桂
- Organizer
  環境化学物質 3 学会合同大会
- Data Source
  KAKENHI-PROJECT-20H00645
[Presentation] Developmental effects of single and binary exposure to estrogenic endocrine disrupting chemicals on zebrafish2022
- Author(s)
  Ahmed, R., Kawai, Y.K. and Kubota, A.
- Organizer
  The 49th Annual Meeting of the Japanese Society of Toxicology
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] Morphological and transcriptome analyses of perfluorinated alkyl substances in zebrafish embryos towards understanding of developmental toxicity and its mechanism2022
- Author(s)
  Jae Seung Lee, Kentaro Matsumoto, Yusuke Kawai, Hiroshi Ishibashi, Akira Kubota
- Organizer
  環境化学物質3学会合同大会
- Data Source
  KAKENHI-PROJECT-20H00634
[Presentation] Mechanistic investigation on distinct estrogenic and developmental responses to bisphenol analogues in zebrafish embryos2022
- Author(s)
  Chen, X., Lee, J.S., Kawai, Y.K., Kubota, A.
- Organizer
  The 49th Annual Meeting of the Japanese Society of Toxicology
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] ゼブラフィッシュ胚を用いた抗精神病剤ハロペリドールの発生毒性と生物濃縮性の評価2022
- Author(s)
  水原奈々 , 田上瑠美 , 久保田彰 , 小椋響子 , 国末達也 , 野見山桂
- Organizer
  環境化学物質 3 学会合同大会
- Data Source
  KAKENHI-PROJECT-20H00645
[Presentation] Role of estrogen receptor in ameliorative effect of estrogen-like compounds on diethylstilbestrol-induced developmental toxicity in zebrafish embryos2022
- Author(s)
  Ahmed, R., Kawai, Y.K. and Kubota, A.
- Organizer
  Joint Conference on Environmental Chemicals
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] Role of calcium signals in circulatory failure and spinal curvature caused by perfluorinated alkyl substances in developing zebrafish2022
- Author(s)
  Lee, J.S., Matsumoto, K., Kawai Y., Ishibashi, H. and Kubota, A.
- Organizer
  The 49th Annual Meeting of the Japanese Society of Toxicology
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] Morphological and transcriptome analyses of perfluorinated alkyl substances in zebrafish embryos towards understanding of developmental toxicity and its mechanism2022
- Author(s)
  Lee, J.S., Matsumoto, K., Kawai Y., Ishibashi, H. and Kubota, A.
- Organizer
  Joint Conference on Environmental Chemicals
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] Role of calcium signals in circulatory failure and spinal curvature caused by perfluorinated alkyl substances in developing zebrafish2022
- Author(s)
  Jae Seung Lee, Kentaro Matsumoto, Yusuke Kawai, Hiroshi Ishibashi, Akira Kubota
- Organizer
  第49回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-20H00634
[Presentation] In vivo and in silico assessment of anti-androgenic potentials for environmental chemicals using zebrafish2022
- Author(s)
  Chen, X., Hirano, M., Kawai, Y.K. and Kubota, A.
- Organizer
  Joint Conference on Environmental Chemicals
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] Estrogenic potency and developmental toxicity of BPA and its alternatives in zebrafish embryos2022
- Author(s)
  Chen Xing, Kawai K Yusuke, Kubota Akira
- Organizer
  5th Chemical Hazard Symposium in Online
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] Assessment of developmental toxicity caused by organophosphate triesters and their metabolites using zebrafish2021
- Author(s)
  Kubota Akira, Lee Jae Seung, Kawai K Yusuke, Covaci Adrian
- Organizer
  The 9th International Congress of Asian Society of Toxicology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] Assessment of developmental toxicity caused by organophosphorus flame retardants and their metabolites in zebrafish embryos2021
- Author(s)
  Lee Jae Seung, Kawai K Yusuke, Morita Yuri, Covaci Adrian, Kubota Akira
- Organizer
  第23回環境ホルモン学会研究発表会
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] Counteracting effect of zearalenone on diethylstilbestrol-induced developmental toxicity in zebrafish2021
- Author(s)
  Salama Rehab, Kawai Yusuke, Kubota Akira
- Organizer
  第23回環境ホルモン学会研究発表会
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] ゼブラフィッシュを用いたリン酸エステル系難燃剤の代謝物の発生毒性評価2021
- Author(s)
  Jae Seung Lee, Yusuke K. Kawai, Yuri Morita, Adrian Covaci, Akira Kubota
- Organizer
  4th International Chemical Hazard Symposium & 第4回日本環境化学会北海道東北／中国四国／毒性部会合同シンポジウム
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] Py-Tag誘導体化法を用いた脳中神経伝達物質とその関連物質の高感度分析法の開発とその応用2021
- Author(s)
  小椋響子、田上瑠美、池中良徳、寺岡宏樹、久保田彰、国末達也、野見山桂
- Organizer
  第29回環境化学討論会
- Data Source
  KAKENHI-PROJECT-20H00645
[Presentation] ゼブラフィッシュを用いたネオニコチノイド系農薬の体内動態と発達神経毒性の解明2021
- Author(s)
  池本秀樹, 沖澤優花, 川合佑典, 一瀬貴大, 池中良徳, 久保田彰
- Organizer
  第23回環境ホルモン学会研究発表会
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] Developmental toxicity of organophosphorus flame retardant metabolites in zebrafish embryos2021
- Author(s)
  Jae Seung Lee, Yuri Morita, Yusuke K. Kawai, Adrian Covaci, Akira Kubota
- Organizer
  日本環境毒性学会第1回オンライン研究発表会
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] Py-Tag誘導体化法を用いた脳中神経伝達物質とその関連物質の高感度分析法の開発とその応用2021
- Author(s)
  小椋響子，田上瑠美，池中良徳，寺岡宏樹, 久保田彰, 国末達也, 野見山桂
- Organizer
  第29回環境化学討論会
- Data Source
  KAKENHI-PROJECT-20H00645
[Presentation] Establishment of evaluation method for anti-androgenic potency of environmental chemicals using zebrafish2021
- Author(s)
  Chen Xing, Kawai K Yusuke, Hirano Masashi, Kubota Akira
- Organizer
  令和3年度日本環境毒性学会オンライン研究発表会
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] Characterization of Cytochrome P450 Genes and Enzymes in the Red-Crowned Cranes: Toward Understanding of Drug Sensitivity2020
- Author(s)
  Kubota Akira、Itou Kiwamu、Sakamoto Rikako、Yamamoto Shuhei、Yoshino Tomoo、Iima Hiroko、Matsumoto Fumio、Nishikawa Miu、Ikushiro Shin-ichi、Kawai Yusuke
- Organizer
  International Symposium on Chemical Hazards to Wildlife（Hokkaido University）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] Developmental effects of organophosphorus flame retardants and their metabolites in zebrafish2019
- Author(s)
  Lee Jae Seung、Morita Yuri、Covaci Adrian、Kawai Yusuke、Kubota Akira
- Organizer
  28th Symposium on Environmental Chemistry
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] In vivo measurement and in silico prediction of estrogen-like potency of bisphenol A and its analogues in zebrafish2019
- Author(s)
  Akira Kubota, Jae Seung Lee, Yumi Wakayama, Michiko Nakamura, Yuka Yoshinouchi, Hisato Iwata, Masashi Hirano, Haruhiko Nakata, Yusuke Kawai
- Organizer
  SOT 58th Annual Meeting and ToxExpo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] In vivo measurement and in silico prediction of estrogenic and anti-estrogenic potency of bisphenol A and its analogues in zebrafish2019
- Author(s)
  Akira Kubota, Jae Seung Lee, Yumi Wakayama, Michiko Nakamura, Yuka Yoshinouchi, Hisato Iwata, Masashi Hirano, Yusuke Kawai
- Organizer
  International Chemical Hazard Symposium in Hokkaido
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] 発達期ゼブラフィッシュにおけるリン酸エステル系難燃剤の代謝物の発生毒性2019
- Author(s)
  久保田彰、イゼスン、森田友理、Adrian Covaci 、川合佑典
- Organizer
  第22回環境ホルモン学会研究発表会
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] Developmental effects of organophosphorus flame retardants and their metabolites in zebrafish2019
- Author(s)
  Kubota Akira、Lee Jae Seung、Morita Yuri、Kawai Yusuke、Covaci Adrian
- Organizer
  39th International Symposium on Halogenated Persistent Organic Pollutants
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] タンチョウ（Grus japonensis）における異物代謝酵素シトクロム P450 1-3 遺伝子の同定・定量と機能解析2019
- Author(s)
  坂本梨果子、伊藤究、西川美宇、生城真一、吉野智生、飯間裕子、松本文雄、川合佑典、久保田彰
- Organizer
  第28回環境化学討論会
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry (LA-ICP-MS) reveals detailed distribution patterns of Pb in mice organs2019
- Author(s)
  Shouta M.M. Nakayama, Masao Togao, Yoshinori Ikenaka, Yoshiki Makino, Ayano Kubota, Takehisa Matsukawa, Kazuhito Yokoyama, Takafumi Hirata, Mayumi Ishizuka
- Organizer
  SETAC North America 40th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04132
[Presentation] ゼブラフィッシュを用いた新世代ビスフェノール類のエストロゲン様作用の比較2019
- Author(s)
  久保田彰、Lee Jae Seung、若山裕己、中村倫子、芳之内結加、岩田久人、平野将司、中田晴彦、川合佑典
- Organizer
  第46回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] In vivo measurement and in silico prediction of estrogen-like potency of bisphenol A and its analogues in zebrafish2019
- Author(s)
  Akira Kubota, Jae Seung Lee, Yumi Wakayama, Michiko Nakamura, Yuka Yoshinouchi, Hisato Iwata, Masashi Hirano, Haruhiko Nakata, Yusuke Kawai
- Organizer
  SOT 58th Annual Meeting and ToxExpo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] ゼブラフィッシュを用いたインビボおよびインシリコ解析によるビスフェノール類の内分泌撹乱作用の評価2019
- Author(s)
  久保田彰、平野将司、イゼスン、中村倫子、芳之内結加、岩田久人、川合佑典
- Organizer
  第25回日本環境毒性学会研究発表会
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] In vivo and in silico analyses of estrogenic potential of equine estrogens in zebrafish (Danio rerio)2019
- Author(s)
  Motomura Chika、Hirano Masashi、Ishibashi Hiroshi、Arizono Koji、Wakayama Yumi、Lee Jae Seung、Kawai Yusuke、Kubota Akira
- Organizer
  3rd International Chemical Hazard Symposium（Hokkaido University）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] In vivo measurement and in silico prediction of estrogenic and anti-estrogenic potency of bisphenol A and its analogues in zebrafish2019
- Author(s)
  Akira Kubota, Jae Seung Lee, Yumi Wakayama, Michiko Nakamura, Yuka Yoshinouchi, Hisato Iwata, Masashi Hirano, Yusuke Kawai
- Organizer
  International Chemical Hazard Symposium in Hokkaido
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] Evolution of Avian UDP-glucuronosyltransferase Genes in Relation to Feeding Habit2019
- Author(s)
  Kawai YK, Shinya S, Nakayama SMM, Ikenaka Y, Ishizuka M, Kubota A
- Organizer
  International Symposium on Chemical Hazard in Wildlife
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04132
[Presentation] ゼブラフィッシュ肝臓におけるシトクロムP450分子種のmRNA発現プロファイル2019
- Author(s)
  久保田彰、川合佑典、山下夏未、Lee Jae Seung、近藤大輔、Zhang Shuangyi 、西康暢、鈴木一由、北澤多喜雄、寺岡宏樹
- Organizer
  第46回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] In silico prediction and in vivo measurement of estrogenic activity of bisphenol analogues in zebrafish2018
- Author(s)
  Akira Kubota, Yumi Wakayama, Michiko Nakamura, Yusuke Kawai, Yuka Yoshinouchi, Hisato Iwata, Masashi Hirano, Haruhiko Nakata
- Organizer
  57th Society of Toxicology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] Assessment of estrogenic and anti-estrogenic potency of bisphenol A replacement in zebrafish2018
- Author(s)
  Jae Seung Lee, Yumi Wakayama, Michiko Nakamura, Yuka Yoshinouchi, Hisato Iwata, Masashi Hirano, Haruhiko Nakata, Yusuke Kawai, Akira Kubota
- Organizer
  第27回環境化学討論会
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] Assessment of estrogenic and anti-estrogenic potency of bisphenol A replacement in zebrafish2018
- Author(s)
  Jae Seung Lee, Yumi Wakayama, Michiko Nakamura, Yuka Yoshinouchi, Hisato Iwata, Masashi Hirano, Haruhiko Nakata, Yusuke Kawai, Akira Kubota
- Organizer
  第27回環境化学討論会
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] ゼブラフィッシュを用いたビスフェノールA代替物質の内分泌攪乱作用の評価2018
- Author(s)
  久保田彰、Jae Seung Lee、若山裕己、中村倫子、川合佑典、芳之内結加、岩田久人、平野将司、中田晴彦
- Organizer
  第45回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] ゼブラフィッシュを用いた生態毒性試験について2018
- Author(s)
  久保田彰
- Organizer
  第12回生態影響試験実習セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] タンチョウにおける異物代謝関連遺伝子の同定と定量2018
- Author(s)
  川合佑典、伊藤究、坂本梨果子、吉野智生、飯間裕子、松本文雄、久保田彰
- Organizer
  第161回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] ゼブラフィッシュを用いた生態毒性試験について2018
- Author(s)
  久保田彰
- Organizer
  第12回生態影響試験実習セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] In silico prediction and in vivo measurement of estrogen-like effects of bisphenol analogues in zebrafish2018
- Author(s)
  Akira Kubota, Yumi Wakayama, Michiko Nakamura, Yusuke Kawai, Yuka Yoshinouchi, Hisato Iwata, Masashi Hirano, Haruhiko Nakata
- Organizer
  SOT 57th Annual Meeting and ToxExpo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] Evaluating estrogenic and anti-estrogenic potency of bisphenol A analogues in vivo and in silico using zebrafish2018
- Author(s)
  Kubota A, Wakayama Y, Lee JS, Nakamura M, Kawai Y, Yoshinouchi Y, Iwata H, Hirano M, Nakata H
- Organizer
  Dioxin2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] タンチョウにおける異物代謝関連遺伝子の同定と定量2018
- Author(s)
  川合佑典、伊藤究、坂本梨果子、吉野智生、飯間裕子、松本文雄、久保田彰
- Organizer
  第161回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] ゼブラフィッシュを用いたビスフェノールA代替物質の内分泌攪乱作用の評価2018
- Author(s)
  久保田彰、Jae Seung Lee、若山裕己、中村倫子、川合佑典、芳之内結加、岩田久人、平野将司、中田晴彦
- Organizer
  第45回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] 十勝の台風被害による飼料用トウモロコシサイレージのかび毒汚染の実態2018
- Author(s)
  久保田彰、Jae Seung Lee、川島千帆
- Organizer
  第45回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] Evaluating estrogenic and anti-estrogenic potency of bisphenol A analogues in vivo and in silico using zebrafish2018
- Author(s)
  Akira Kubota, Yumi Wakayama, Jae Seung Lee, Michiko Nakamura, Yusuke Kawai, Yuka Yoshinouchi, Hisato Iwata, Masashi Hirano, Haruhiko Nakata
- Organizer
  38th International Symposium on Halogenated Persistent Organic Pollutants
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] In Silico Prediction and In Vivo Measurement of Estrogen-Like Effects of Bisphenol Analogues in Zebrafish2018
- Author(s)
  Kubota A, Wakayama Y, Lee JS, Nakamura M, Kawai Y, Yoshinouchi Y, Iwata H, Hirano M, Nakata H
- Organizer
  SOT 57th Annual Meeting and ToxExpo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] 十勝の台風被害による飼料用トウモロコシサイレージのかび毒汚染の実態2018
- Author(s)
  久保田彰、Jae Seung Lee、川島千帆
- Organizer
  第45回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] In vivo and in silico assessment of estrogen-like effects of bisphenol analogues in zebrafish2017
- Author(s)
  Yumi Wakayama, Michiko Nakamura, Yuri Morita, Yuka Yoshinouchi, Hisato Iwata, Masashi Hirano, Haruhiko Nakata, Yusuke Kawai, Akira Kubota
- Organizer
  19th International Symposium on Pollutant Responses in Marine Organisms
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] 有機リン系難燃剤およびその代謝物による発達期ゼブラフィッシュに対する影響2017
- Author(s)
  森田友理、若山裕己、芳之内結加、岩田久人、川合佑典、久保田　彰
- Organizer
  第44回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] ゼブラフィッシュをモデルとしたin vivoおよびin silico解析によるビスフェノール類のエストロゲン様作用の評価2017
- Author(s)
  中村倫子、若山裕己、芳之内結加、森田友理、岩田久人、川合佑典、久保田　彰
- Organizer
  第44回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] Evolution of avian UGT family genes in relation to feeding habit2017
- Author(s)
  Yusuke Kawai, Yoshinori Ikenaka, Mayumi Ishizuka, Akira Kubota
- Organizer
  19th International Symposium on Pollutant Responses in Marine Organisms
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] In silico prediction and in vivo measurement of estrogenic activity of bisphenol analogues in zebrafish2017
- Author(s)
  Akira Kubota, Yumi Wakayama, Michiko Nakamura, Yusuke Kawai, Yuka Yoshinouchi, Hisato Iwata, Masashi Hirano, Haruhiko Nakata
- Organizer
  20th International Conference on Cytochrome P450
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] In vivo and in silico assessment of estrogen-like effects of bisphenol analogues in zebrafish2017
- Author(s)
  Yumi Wakayama, Michiko Nakamura, Yuri Morita, Yuka Yoshinouchi, Hisato Iwata, Masashi Hirano, Haruhiko Nakata, Yusuke Kawai, Akira Kubota
- Organizer
  19th International Symposium on Pollutant Responses in Marine Organisms (PRIMO19）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] 有機リン系難燃剤およびその代謝物による発達期ゼブラフィッシュに対する影響2017
- Author(s)
  森田友理、若山裕己、芳之内結加、岩田久人、川合佑典、久保田　彰
- Organizer
  第44回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] ゼブラフィッシュをモデルとしたin silicoおよびin vivo解析によるビスフェノール類のエストロゲン様作用の評価2017
- Author(s)
  久保田彰、若山裕己、中村倫子、川合佑典、芳之内結加、岩田久人、平野将司、中田晴彦
- Organizer
  環境ホルモン学会　第20回研究発表会
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] In silico prediction and in vivo measurement of estrogenic activity of bisphenol analogues in zebrafish2017
- Author(s)
  Akira Kubota, Yumi Wakayama, Michiko Nakamura, Yusuke Kawai, Yuka Yoshinouchi, Hisato Iwata, Masashi Hirano, Haruhiko Nakata
- Organizer
  20th International Conference on Cytochrome P450
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] ゼブラフィッシュをモデルとしたin vivoおよびin silico解析によるビスフェノール類のエストロゲン様作用の評価2017
- Author(s)
  中村倫子、若山裕己、芳之内結加、森田友理、岩田久人、川合佑典、久保田　彰
- Organizer
  第44回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] ゼブラフィッシュ胚を用いたin silicoおよびin vivo解析によるビスフェノール類のエストロゲン様作用の評価2017
- Author(s)
  川合佑典、中村倫子、若山裕己、森田友理、芳之内結加、平野将司、中田晴彦、岩田久人、久保田　彰
- Organizer
  第26回環境化学討論会
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] In vivo and in silico assessment of estrogen-like effects of bisphenol analogues in zebrafish2017
- Author(s)
  Yumi Wakayama, Michiko Nakamura, Yuri Morita, Yuka Yoshinouchi, Hisato Iwata, Masashi Hirano, Haruhiko Nakata, Yusuke Kawai, Akira Kubota
- Organizer
  19th International Symposium on Pollutant Responses in Marine Organisms(PRIMO19)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] Evolution of avian UGT family genes in relation to feeding habit2017
- Author(s)
  Yusuke Kawai, Yoshinori Ikenaka, Mayumi Ishizuka, Akira Kubota
- Organizer
  19th International Symposium on Pollutant Responses in Marine Organisms(PRIMO19)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] ゼブラフィッシュをモデルとしたin silicoおよびin vivo解析によるビスフェノール類のエストロゲン様作用の評価2017
- Author(s)
  久保田彰・若山裕己・中村倫子・川合佑典・芳之内結加・岩田久人・平野将司・中田晴彦
- Organizer
  第２０回環境ホルモン学会
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] ゼブラフィッシュにおける薬物代謝酵素の網羅的解析：魚類とヒト健康影響のモデル動物の観点から2016
- Author(s)
  久保田彰
- Organizer
  環境リスク・健康研究センター特別講演会
- Place of Presentation
  国立環境研究所（茨城県つくば市）
- Invited
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] 発達期ゼブラフィッシュにおけるCYP1A/AHRフィードバック機構攪乱の影響2016
- Author(s)
  久保田彰，Emma Wincent，John Stegeman
- Organizer
  第22回日本環境毒性学会研究発表会
- Place of Presentation
  愛媛大学（愛媛県・松山市）
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] Characterization of a Pxr-null zebrafish2016
- Author(s)
  Matthew C. Salanga, Akira Kubota, Benjamin Lemaire, Rachel Harbeitner, Daniel Gusenleitner, Stefano Monti, John J. Stegeman, Jared V. Goldstone
- Organizer
  55th Annual Meeting of Society of Toxicology
- Place of Presentation
  ニューオーリンズ（米国）
- Year and Date
  2016-03-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] メコン川および紅河流域における地下水のヒ素汚染2016
- Author(s)
  阿草哲郎、岩田久人、井上英、Karri Ramu、Nguyen M. Tue、田辺信介、國頭恭、久保田領志、Tu B. Minh、Pham T. K. Trang、Pham H. Viet、Nguyen N. Ha、Nguyen P. C. Tu、Bui C. Tuyen、Paromita Charaborty、Chhoun Chamnan、Alissara Reungsang, Kriengsak Srisuk、中村哲、滝沢智、高橋真、Annamalai Subramanian、Touch S. Tana
- Organizer
  第50回日本水環境学会年回
- Place of Presentation
  アスティとくしま（徳島県徳島市）
- Year and Date
  2016-03-16
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] Biological effects of a dysfunctional CYP1A/AHR2 feedback loop in developing zebrafish2016
- Author(s)
  Kubota, A., Timme-Laragy, A., Jonsson, M., Hahn, M. E., Stegeman, J. J. and Wincent, E.
- Organizer
  環境ホルモン学会第19回研究発表会
- Place of Presentation
  文科省研究交流センター（茨城県・つくば市）
- Year and Date
  2016-12-08
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] 発達期ゼブラフィッシュにおけるCYP1A/AHRフィードバック機構攪乱の影響2016
- Author(s)
  久保田　彰，Wincent, E., Stegeman, J.
- Organizer
  第22回日本環境毒性学会研究発表会
- Place of Presentation
  愛媛大学（愛媛県・松山市）
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] Biological effects of a dysfunctional CYP1A/AHR2 feedback loop in developing zebrafish2016
- Author(s)
  Akira Kubota, Alicia Timme-Laragy, Maria Jonsson, Mark E. Hahn, John J. Stegeman, Emma Wincent
- Organizer
  環境ホルモン学会　第19回研究発表会
- Place of Presentation
  文部科学省　研究交流センター（茨城県つくば市）
- Year and Date
  2016-12-08
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] Characterization of a Pxr-null zebrafish2016
- Author(s)
  Salanga, M. C., Kubota, A., Lemaire, B., Harbeitner, R., Gusenleitner, D., Monti, S., Stegeman, J. J. and Goldstone, J. V.
- Organizer
  55th Annual Meeting of Society of Toxicology
- Place of Presentation
  Ernest N. Morial Convention Center（ニューオーリンズ、アメリカ合衆国）
- Year and Date
  2016-03-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] 発達期ゼブラフィッシュをモデルとした化学物質の毒性発現機構の解析2016
- Author(s)
  久保田彰
- Organizer
  第7回LaMer特別講演会
- Place of Presentation
  愛媛大学（愛媛県・松山市）
- Invited
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] Reciprocal cross-talk between Ahr2 and Pxr signaling in response to PCB126 and pregnenolone in developing zebrafish2016
- Author(s)
  Akira Kubota, Jared Goldstone, John Stegeman
- Organizer
  The 9th International PCB Workshop
- Place of Presentation
  神戸国際会議場（兵庫県・神戸市）
- Year and Date
  2016-10-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] Role of pregnane X receptor and aryl hydrocarbon receptor in transcriptional regulation of PXR, CYP2, and CYP3 genes in developing zebrafish2015
- Author(s)
  Akira Kubota, Jared V. Goldstone, Benjamin Lemaire, John J. Stegeman
- Organizer
  19th International Conference on Cytochrome P450
- Place of Presentation
  国立オリンピック記念青少年総合センター（東京都・渋谷区）
- Year and Date
  2015-06-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] The PXR "gene battery" in zebrafish2015
- Author(s)
  Goldstone, J.V., Harbeitner, R., Kubota, A., Lemaire, B., Stegeman, J.J.
- Organizer
  18th International symposium on Pollutant Responses in Marine Organisms (PRIMO18)
- Place of Presentation
  ノルウェー・トロンハイム
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PROJECT-26881001
[Presentation] ゼブラフィッシュのリガンド依存性転写因子とシトクロムP4502015
- Author(s)
  久保田　彰、Jared V. Goldstone, Emma Wincent, John J. Stegeman
- Organizer
  第42回日本毒性学会学術年会
- Place of Presentation
  ホテル日航金沢（石川県金沢市）
- Year and Date
  2015-07-01
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] Zebrafish PXR inhibition in vivo by human PXR agonists2015
- Author(s)
  Stegeman, J.J., Lemaire, B., Kubota, A., Harbeitner, R., Goldstone, J.V.
- Organizer
  54th Annual Meeting of Society of Toxicology
- Place of Presentation
  米国・サンディエゴ
- Year and Date
  2015-03-25
- Data Source
  KAKENHI-PROJECT-26881001
[Presentation] Regulation of CYP genes by AHR and PXR in zebrafish2015
- Author(s)
  Kubota, A.
- Organizer
  Leading symposium on molecular targets of environmental chemicals
- Place of Presentation
  北海道大学
- Year and Date
  2015-02-10
- Invited
- Data Source
  KAKENHI-PROJECT-26881001
[Presentation] Cytochrome P450 20A1: Diversity and potential functions of a major orphan P450s2015
- Author(s)
  Lemaire, B., Goldstone, J.V., Lamb, D., Kubota, A., Nelson, D., Stegeman, J.J.
- Organizer
  54th Annual Meeting of Society of Toxicology
- Place of Presentation
  米国・サンディエゴ
- Year and Date
  2015-03-23
- Data Source
  KAKENHI-PROJECT-26881001
[Presentation] Transcriptomic effects of ortho-PCBs on developing zebrafish2015
- Author(s)
  Goldstone, J.V., Lemaire, B., Kubota, A., Stegeman, J.J.
- Organizer
  54th Annual Meeting of Society of Toxicology
- Place of Presentation
  米国・サンディエゴ
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-26881001
[Presentation] 野生鳥類におけるダイオキシン類のエコトキシコロジー2015
- Author(s)
  久保田彰
- Organizer
  第21回日本野生動物医学会大会
- Place of Presentation
  酪農学園大学（北海道江別市）
- Year and Date
  2015-07-31
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] Differences in responses to putative PXR agonists associated with PXR alleles in zebrafish embryos2015
- Author(s)
  Kubota, A., Goldstone, J. V., Lemaire, B., Harbeitner, R., Salay, L. and Stegeman, J. J.
- Organizer
  18th International Symposium on Pollutant Responses in Marine Organisms
- Place of Presentation
  クラリオンホテル＆コングレス（トロンハイム、ノルウェイ）
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] Zebrafish PXR inhibition in vivo by human PXR agonists2015
- Author(s)
  Stegeman, J.J., Lemaire, B., Kubota, A., Harbeitner, R., Goldstone, J.V.
- Organizer
  Society of Toxicology (SOT) 54th Annual Meeting
- Place of Presentation
  サンディエゴ、アメリカ
- Year and Date
  2015-03-25
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] Contamination by arsenic and other trace elements in groundwater from the Red and Mekong River Deltas2015
- Author(s)
  Agusa, T., Iwata, H., Kunito, T., Inoue, S., Kubota, R., Karri, R., Minh, T. B., Tue, N. M., Ha, N. N., Tu, N. P. C., Charaborty, P., Chamnan, C., Trang, P. T. K., Reungsang, A., Srisuk, K., Nakamura, S., Takizawa, S., Subramanian, A., Tuyen, B. C., Viet, P. H., Tana, T. S. and Tanabe, S.
- Organizer
  The Second Myanmar-Japan Symposium
- Place of Presentation
  Pathein University(パテイン, ミャンマー)
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] 魚類におけるPXR・AHRを介したシトクロムP450発現制御機構の特徴2015
- Author(s)
  久保田　彰, Jared V. Goldstone, John J. Stegeman
- Organizer
  第21回日本環境毒性学会研究発表会
- Place of Presentation
  東洋大学白山キャンパス（東京都・文京区）
- Year and Date
  2015-09-02
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] Transcriptomic effects of ortho-PCBs on developing zebrafish2015
- Author(s)
  Goldstone, J.V., Lemaire, B., Kubota, A., Stegeman, J.J.
- Organizer
  Society of Toxicology (SOT) 54th Annual Meeting
- Place of Presentation
  サンディエゴ、アメリカ
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] Reciprocal cross-talk between PXR and AHR2 signaling in response to their putative agonists in developing zebrafish2015
- Author(s)
  Kubota, A., Goldstone, J. V., Lemaire, B., Takata, M., Woodin, B. R. and Stegeman, J. J.
- Organizer
  18th International Symposium on Pollutant Responses in Marine Organisms
- Place of Presentation
  クラリオンホテル＆コングレス（トロンハイム、ノルウェイ）
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] The PXR “gene battery” in zebrafish2015
- Author(s)
  Jared V. Goldstone, Rachel Harbeitner, Akira Kubota, Benjamin Lemaire, John J. Stegeman
- Organizer
  18th International symposium on Pollutant Responses in Marine Organisms
- Place of Presentation
  トロンハイム（ノルウェー）
- Year and Date
  2015-05-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] Role of pregnane X receptor and aryl hydrocarbon receptor in transcriptional regulation of pxr, CYP2 and CYP3 genes in developing zebrafish2015
- Author(s)
  Kubota, A., Goldstone, J. V., Lemaire, B., and Stegeman, J. J.
- Organizer
  第24回環境化学討論会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] 魚類におけるシトクロムP450の発現制御機構と代謝特性2015
- Author(s)
  久保田　彰, John J. Stegeman
- Organizer
  第42回日本毒性学会学術年会
- Place of Presentation
  石川県立音楽堂、金沢市アートホテル、ホテル日航金沢（石川県・金沢市）
- Year and Date
  2015-06-29
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] The PXR “gene battery” in zebrafish2015
- Author(s)
  Goldstone, J. V., Harbeitner, R., Kubota, A., Lemaire, B. and Stegeman, J. J.
- Organizer
  18th International Symposium on Pollutant Responses in Marine Organisms
- Place of Presentation
  クラリオンホテル＆コングレス（トロンハイム、ノルウェイ）
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] Differences in responses to putative PXR agonists associated with PXR alleles in zebrafish embryos2015
- Author(s)
  Akira Kubota, Jared V. Goldstone, Benjamin Lemaire, Rachel Harbeitner, Lauren Salay, John J. Stegeman
- Organizer
  18th International symposium on Pollutant Responses in Marine Organisms
- Place of Presentation
  トロンハイム（ノルウェー）
- Year and Date
  2015-05-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] Role of pregnane X receptor and aryl hydrocarbon receptor in transcriptional regulation of PXR, CYP2, and CYP3 genes in developing zebrafish2015
- Author(s)
  Kubota, A., Goldstone, J. V., Lemaire, B. and Stegeman, J. J.
- Organizer
  19th International Conference on Cytochrome P450 Biochemistry, Biophysics, and Biotechnology
- Place of Presentation
  国立オリンピック記念青少年総合センター（東京都渋谷区）
- Year and Date
  2015-06-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] Arsenic exposure in residents from arsenic-contaminated groundwater areas of Southeast Asia2015
- Author(s)
  Agusa, T., Kunito, T., Kubota, R., Tanabe, S. and Iwata, H.
- Organizer
  ASIATOX2015 (The 7th International Congress of Asian Society of Toxicology)
- Place of Presentation
  International Convention Center Jeju（チェジュ、韓国）
- Year and Date
  2015-06-24
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] ゼブラフィッシュのリガンド依存性転写因子とシトクロムP4502015
- Author(s)
  久保田　彰, Jared V. Goldstone, Emma Wincent, John J. Stegeman
- Organizer
  第42回日本毒性学会学術年会
- Place of Presentation
  石川県立音楽堂、金沢市アートホテル、ホテル日航金沢（石川県・金沢市）
- Year and Date
  2015-06-29
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] Reciprocal cross-talk between PXR and AHR2 signaling in response to their putative agonists in developing zebrafish2015
- Author(s)
  Kubota, A., Goldstone, J.V., Lemaire, B., Takata, M., Woodin, B.R., Stegeman, J.J.
- Organizer
  18th International symposium on Pollutant Responses in Marine Organisms (PRIMO18)
- Place of Presentation
  ノルウェー・トロンハイム
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PROJECT-26881001
[Presentation] Cytochrome P450 20A1: Diversity and potential functions of a major orphan P450s2015
- Author(s)
  Lemaire, B., Goldstone, J.V., Lam, D., Kubota, A., Nelson, D., Stegeman, J.J.
- Organizer
  Society of Toxicology (SOT) 54th Annual Meeting
- Place of Presentation
  サンディエゴ、アメリカ
- Year and Date
  2015-03-23
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] Reciprocal cross-talk between PXR and AHR2 signaling in response to their putative agonists in developing zebrafish2015
- Author(s)
  Akira Kubota, Jared V. Goldstone, Benjamin Lemaire, Matthew Takata, Bruce R. Woodin, John J. Stegeman
- Organizer
  18th International symposium on Pollutant Responses in Marine Organisms
- Place of Presentation
  トロンハイム（ノルウェー）
- Year and Date
  2015-05-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05334
[Presentation] 魚類におけるPXR・AHRを介したシトクロムP450発現制御機構の特徴2015
- Author(s)
  久保田　彰、Jared V. Goldstone、 John J. Stegeman
- Organizer
  第21回日本環境毒性学会研究発表会
- Place of Presentation
  東洋大学（東京都文京区）
- Year and Date
  2015-09-02
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] Differences in responses to putative PXR agonists associated with PXR alleles in zebrafish embryos2015
- Author(s)
  Kubota, A., Goldstone, J.V., Lemaire, B., Harbeitner, R., Salay, L., Stegeman, J.J.
- Organizer
  18th International symposium on Pollutant Responses in Marine Organisms (PRIMO18)
- Place of Presentation
  ノルウェー・トロンハイム
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PROJECT-26881001
[Presentation] 魚類におけるシトクロムP450の発現制御機構と代謝特性2015
- Author(s)
  久保田　彰、John J. Stegeman
- Organizer
  第42回日本毒性学会学術年会
- Place of Presentation
  ホテル日航金沢（石川県金沢市）
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] Studies on environmental toxicology with zebrafish: Toward understanding characteristics and molecular mechanisms of developmental toxicity of chemicals2014
- Author(s)
  Kubota, A., Teraoka, H., Stegeman, J.J.
- Organizer
  7th International Conference on Environmental Health Science
- Place of Presentation
  韓国・ソウル
- Year and Date
  2014-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-26881001
[Presentation] PXR and AHR both are involved in transcriptional regulation of pxr, CYP2 and CYP3 genes in developing zebrafish2014
- Author(s)
  Kubota, A., Goldstone, J.V., Lemaire, B., Stegeman, J.J.
- Organizer
  環境ホルモン学会第17回研究発表会
- Place of Presentation
  東京都文京区、日本
- Year and Date
  2014-12-10
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] PXR and AHR both are involved in transcriptional regulation of pxr, CYP2 and CYP3 genes in developing zebrafish2014
- Author(s)
  Kubota, A., Goldstone, J.V., Lemaire, B., Stegeman, J.J.
- Organizer
  環境ホルモン学会第17回研究発表会
- Place of Presentation
  東京大学
- Year and Date
  2014-12-10
- Data Source
  KAKENHI-PROJECT-26881001
[Presentation] ゼブラフィッシュのシトクロムP450 －分子種多様性・発現制御・毒性学的役割を中心に2014
- Author(s)
  久保田彰
- Organizer
  第28回北海道薬物作用談話会
- Place of Presentation
  北海道札幌市、日本
- Year and Date
  2014-07-19
- Invited
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] Studies on environmental toxicology with zebrafish: Toward understanding characteristics and molecular mechanisms of developmental toxicity of chemicals2014
- Author(s)
  Kubota, A., Teraoka, H., Stegeman, J.J.
- Organizer
  7th International Conference on Environmental Health Science
- Place of Presentation
  ソウル、韓国
- Year and Date
  2014-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-26220103
[Presentation] ウミガメ類におけるヒ素化合物の蓄積特性2014
- Author(s)
  阿草哲郎、高木　梢、Todd W. Miller、久保田領志、阿南弥寿美、岩田久人、田辺信介
- Organizer
  第２０回ヒ素シンポジウム
- Place of Presentation
  千葉県銚子市、日本
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-26220103

1. Nomiyama Kei (30512686)

# of Collaborated Projects: 6 results

# of Collaborated Products: 13 results
2. IWATA Hisato (10271652)

# of Collaborated Projects: 5 results

# of Collaborated Products: 17 results
3. 川合佑典 (10709546)

# of Collaborated Projects: 5 results

# of Collaborated Products: 39 results
4. 田上瑠美 (60767226)

# of Collaborated Projects: 5 results

# of Collaborated Products: 12 results
5. Kunisue Tatsuya (90380287)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
6. IKENAKA Yoshinori (40543509)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
7. 江口哲史 (70595826)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. 有薗幸司 (70128148)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 加藤恵介 (80276609)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 寳來佐和子 (60512689)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. Toyotome Takahito (90422245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 阿草哲郎 (50403853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
13. 田辺信介 (60116952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
14. 中田晴彦 (60311875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
15. 星信彦 (10209223)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 石塚真由美 (50332474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
17. 小林篤史 (50431507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 水川葉月 (60612661)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. 平野哲史 (70804590)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 宮原裕一 (80311330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 市川剛 (80438712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 岡松優子 (90527178)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 中山翔太 (90647629)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
24. 近藤大輔 (90708364)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. 石橋弘志 (90403857)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
26. 高橋真 (30370266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. 川嶋文人 (60346690)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 藤森崇 (20583248)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 日下部太一 (00600032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 冨永伸明 (30227631)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 平野将司 (20554471)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
32. 村田幸久 (40422365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
33. 中村達朗 (80755554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
34. 生城真一 (50244679)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 武田一貴 (00896350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 郭新宇 (10322273)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 浅岡聡 (60548981)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. Chen Xing

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
39. 寺岡宏樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kubota Akira 久保田 彰

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Development and clinical application of a non-invasive drug sensitivity assessment method for ex situ conservation of threatened avian speciesPrincipal Investigator

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Whole embryo screening and integrated omics approach using zebrafish for unraveling mechanisms underlying chemical toxicitiesPrincipal Investigator

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Assessment of developmental toxicities caused by chemical substances and elucidation of their mechanisms based on the quantitative phenotype screening using small fishPrincipal Investigator

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Understanding of molecular mechanisms of chemically-induced toxicities and risk evaluation using zebrafishPrincipal Investigator

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魚類の核内受容体PXRシグナル経路の撹乱に関わる新規分子機構とその毒性学的意義Principal Investigator

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[Journal Article] Assessment of developmental toxicity and the potential mode of action underlying single and binary exposure to estrogenic endocrine disrupting chemicals in zebrafish (Danio rerio)2024

Kubota Akira 久保田彰