Masaki Ishikawa 石河真幸

… Alternative Names

石河真幸イシカワマサキ

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Researcher Number	60432936
Other IDs
Affiliation (based on the past Project Information) *help	2015 – 2021: 東北大学, 大学病院, 助教 2017: 東北大学, 歯学研究科, 助教 2007: 九大, 大学病院, 助手 2006: 九州大学, 大学院歯学研究院, 助手
Review Section/Research Field	Principal Investigator Conservative dentistry / Basic Section 57030:Conservative dentistry-related / Medium-sized Section 57:Oral science and related fields Except Principal Investigator Periodontology / Orthodontics/Pediatric dentistry
Keywords	Principal Investigator Gap junction / 骨再生 / 再生医療 / 骨芽細胞 / Pannexin / 発生・分化 / 歯学 / 細胞・組織 / 再生医学 / ATP … More / ギャップジャンクション / 炎症 / 幹細胞 / 幹細胞ニッチ / Gap junction protein / 口腔免疫 / 造血幹細胞 / 微小環境 / 免疫細胞分化 / 骨髄ニッチ / 骨髄幹細胞 / 発現制御 / 抗炎症作用 / 再生 / 歯科保存 / カルシウム　シグナル / 歯周病 / 2nd メッセンジャー / 抗炎症 / 軟骨細胞分化 / 骨芽細胞分化 / 骨形成 / ギャップ　ジャンクション / 再生治療 / 移植・再生医療 / inflammation / Ca2+ channel / 変形性膝関節炎 / 細胞内シグナリング / 細胞周期 / 細胞の増殖、分化 / 歯内治療 … More Except Principal Investigator 医療 / バイオテクノロジー / 循環器 / トランスレーショナルリサーチ / 歯学 / 弾性システム / モノクローナル抗体 / 歯周炎 / 解離性大動脈瘤 / イメージング診断 / 細胞外マトリックス / 組織破壊 / マルファン症候群 / 結合組織疾患 / 増殖因子 / 細胞間結合 / 再生医療 Less

メカノセンサー象牙芽細胞の咀嚼刺激受容と脳活性Principal Investigator
- Principal Investigator
  
  石河真幸
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Tohoku University
Pannexin 3 provides bone marrow niche for B- and T cell differentiation.Principal Investigator
- Principal Investigator
  
  Ishikawa Masaki
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Tohoku University
Anti-locomotive syndrome by regulating Pannexin 3 function(Fostering Joint International Research)Principal Investigator
- Principal Investigator
  
  Ishikawa Masaki
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  Conservative dentistry
- Research Institution
  Tohoku University
Analysis of growth factor - intercellular communication during dental epithelial and mesenchymal cell differentiation.
- Principal Investigator
  
  YAMADA AYA
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Tohoku University
Development of novel diagnostic technology for marfan syndrome using periodontal tissue
- Principal Investigator
  
  Saito Masahiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Periodontology
- Research Institution
  Tohoku University
The development of anti-inflammatory and regenerative medicine for periodontitis: application of Pannexin 3 signaling pathways.Principal Investigator
- Principal Investigator
  
  Masaki Ishikawa
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Tohoku University
Pannexin3の機能を応用した新骨再生療法の開発Principal Investigator
- Principal Investigator
  
  石河真幸
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Conservative dentistry
- Research Institution
  Tohoku University
歯髄幹細胞維持に必要な微小環境の同定と再生医療への応用Principal Investigator
- Principal Investigator
  
  石河真幸
- Project Period (FY)
  2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Kyushu University
幹細胞を利用した新歯内治療法の確立Principal Investigator
- Principal Investigator
  
  石河真幸
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Conservative dentistry
- Research Institution
  Kyushu University

All 2021 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Pannexin 3 regulates skin development via Epiprofin2021
- Author(s)
  Zhang Peipei、Ishikawa Masaki、Doyle Andrew、Nakamura Takashi、He Bing、Yamada Yoshihiko
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1
- DOI
  10.1038/s41598-021-81074-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22698, KAKENHI-PROJECT-16KK0196
[Journal Article] Pannexin 3 ER Ca2+ channel gating is regulated by phosphorylation at the Serine 68 residue in osteoblast differentiation2019
- Author(s)
  Ishikawa Masaki、Williams Geneva、Forcinito Patricia、Ishikawa Momoko、Petrie Ryan J.、Saito Kan、Fukumoto Satoshi、Yamada Yoshihiko
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 18759-18759
- DOI
  10.1038/s41598-019-55371-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22698, KAKENHI-PROJECT-17H01606, KAKENHI-PROJECT-18H03009
[Journal Article] Fibrillin-1 insufficiency alters periodontal wound healing failure in a mouse model of Marfan syndrome.2018
- Author(s)
  Handa K, Abe S, Suresh VV, Fujieda Y, Ishikawa M, Orimoto A, Kobayashi Y, Yamada S, Yamaba S, Murakami S, Saito M.
- Journal Title
  
  Arch Oral Biol.
  
  Volume: 90 Pages: 53-60
- DOI
  10.1016/j.archoralbio.2018.02.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K11104, KAKENHI-PROJECT-16K15844, KAKENHI-PROJECT-16H05514
[Journal Article] Pannexin-3 Deficiency Delays Skin Wound Healing in Mice due to Defects in Channel Functionality2018
- Author(s)
  Zhang Peipei、Ishikawa Masaki、Rhodes Craig、Doyle Andrew、Ikeuchi Tomoko、Nakamura Kuniyuki、Chiba Yuta、He Bing、Yamada Yoshihiko
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: 139(4) Issue: 4 Pages: 909-918
- DOI
  10.1016/j.jid.2018.08.033
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05514, KAKENHI-PROJECT-19K21375
[Journal Article] Metal ions from S‐PRG filler have the potential to prevent periodontal disease2017
- Author(s)
  Yoko Iwamatsu‐Kobayashi, Syouta Abe, Yoshiyasu Fujieda, Ai Orimoto, Masafumi Kanehira, Keisuke Handa, Venkata Suresh Venkataiah, Wei Zou, Masaki Ishikawa, Masahiro Saito
- Journal Title
  
  Clinical and Experiment Dental Research
  
  Volume: 3 Issue: 4 Pages: 126-133
- DOI
  10.1002/cre2.70
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17588, KAKENHI-PROJECT-16K15844
[Journal Article] The SCFβ-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis.2017
- Author(s)
  Shimizu K, Fukushima H, Ogura K, Lien EC, Nihira NT, Zhang J, North BJ, Guo A, Nagashima K, Nakagawa T, Hoshikawa S, Watahiki A, Okabe K, Yamada A, Toker A, Asara JM, Fukumoto S, Nakayama KI, Nakayama K, Inuzuka H, Wei W.
- Journal Title
  
  Sci Signal. doi: 10.1126/scisignal.aah4117.
  
  Volume: 10 Issue: 460 Pages: 1-15
- DOI
  10.1126/scisignal.aah4117
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253092, KAKENHI-PROJECT-16H05509, KAKENHI-PROJECT-16H05529, KAKENHI-PROJECT-16H05548, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-16K14664, KAKENHI-PROJECT-15K18365, KAKENHI-PROJECT-15K18977, KAKENHI-PROJECT-15K15689, KAKENHI-PROJECT-17K10432, KAKENHI-PROJECT-26462829
[Journal Article] The Role of Pannexin 3 in Bone Biology2017
- Author(s)
  Ishikawa M, Yamada Y
- Journal Title
  
  J Dent Res
  
  Volume: Apr;96 Issue: 4 Pages: 372-379
- DOI
  10.1177/0022034516678203
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05514
[Journal Article] Mediator 1 contributes to enamel mineralization as a coactivator for Notch1 signaling and stimulates transcription of the alkaline phosphatase gene2017
- Author(s)
  Yoshizaki Keigo、Hu Lizhi、Nguyen Thai、Sakai Kiyoshi、Ishikawa Masaki、Takahashi Ichiro、Fukumoto Satoshi、DenBesten Pamela K.、Bikle Daniel D.、Oda Yuko、Yamada Yoshihiko
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 292 Issue: 33 Pages: 13531-13540
- DOI
  10.1074/jbc.m117.780866
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19765, KAKENHI-PROJECT-17K15645, KAKENHI-PROJECT-17H01606, KAKENHI-PROJECT-16H05514, KAKENHI-PROJECT-17H04415, KAKENHI-PROJECT-15H05688
[Journal Article] Pannexin 3 regulates proliferation and differentiation of odontoblasts via its hemichannel activities2017
- Author(s)
  Iwamoto Tsutomu、Nakamura Takashi、Ishikawa Masaki、Yoshizaki Keigo、Sugimoto Asuna、Ida-Yonemochi Hiroko、Ohshima Hayato、Saito Masahiro、Yamada Yoshihiko、Fukumoto Satoshi
- Journal Title
  
  PLOS ONE
  
  Volume: 12 Issue: 5 Pages: 0177557-0177557
- DOI
  10.1371/journal.pone.0177557
- NAID
  120006534958
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19765, KAKENHI-PROJECT-17H01606, KAKENHI-PROJECT-15H05032, KAKENHI-PROJECT-16H05514, KAKENHI-PROJECT-17H04366, KAKENHI-PROJECT-17H04414, KAKENHI-PROJECT-17H04415, KAKENHI-PROJECT-15H05688, KAKENHI-PROJECT-15K15752
[Journal Article] F-spondin negatively regulates dental follicle differentiation through the inhibition of TGF-beta activity.2017
- Author(s)
  Orimoto A, Kurokawa M, Handa K, Ishikawa M, Nishida E, Aino M, Mitani A, Ogawa M, Tsuji T Saito M
- Journal Title
  
  Arch Oral Biol
  
  Volume: 79 Pages: 7-13
- DOI
  10.1016/j.archoralbio.2017.02.019
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293404, KAKENHI-PROJECT-26870678, KAKENHI-PROJECT-16K20684, KAKENHI-PROJECT-16K11845, KAKENHI-PROJECT-17K11998, KAKENHI-PROJECT-16H05514, KAKENHI-PROJECT-15K11104, KAKENHI-PROJECT-16K15844
[Journal Article] Pannexin 3 and connexin 43 modulate skeletal development through their distinct functions and expression patterns.2016
- Author(s)
  Ishikawa M, Williams GL, Ikeuchi T, Sakai K, Fukumoto S, Yamada Y.
- Journal Title
  
  J Cell Sci.
  
  Volume: 129 Issue: 5 Pages: 1018-1030
- DOI
  10.1242/jcs.176883
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670880, KAKENHI-PROJECT-26253092, KAKENHI-PROJECT-15H06042
[Presentation] The role of gap junction protein skeletal biology: points of view from Pannexin 3 and Connexin 43.2018
- Author(s)
  Masaki Ishikawa
- Organizer
  Skeletal Biology Interest Group Special Seminar in NIDCR.
- Invited
- Data Source
  KAKENHI-PROJECT-16H05514
[Presentation] Pannexin 3 ER Ca2+ channel gating is regulated by phosphorylation at Serine 68 residue to promote osteoblast differentiation.2018
- Author(s)
  Masaki Ishikawa
- Organizer
  Bones & Teeth Gordon Research conferences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05514
[Presentation] Pannexin 3 ER Ca2+ channel gating is regulated by phosphorylation at Serine 68 residue to promote osteoblast differentiation2018
- Author(s)
  Masaki ishikawa
- Organizer
  Bones & Teeth Gordon Research conferences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05514
[Presentation] ADAMTS superfamilyによるMarfan症候群の解離性大動脈瘤発症機構の解析2017
- Author(s)
  折本愛、石河真幸、半田慶介、千々岩みゆき、望月早月、村澤祐介、磯貝善蔵、岡田保典、齋藤正寛
- Organizer
  結合組織学会
- Data Source
  KAKENHI-PROJECT-16K15844
[Presentation] The role of gap junctin proteins in skeletal biology : points of view from Pannexin 3 and Connexin 432017
- Author(s)
  Masaki Ishikawa
- Organizer
  Consortium of Biological Sciences 2017
- Invited
- Data Source
  KAKENHI-PROJECT-16H05514
[Presentation] Pannexin 3 is a new regulator for bone formation2017
- Author(s)
  Masaki Ishikawa
- Organizer
  The 49th Annual Meeting of the Japanese Society for Matrix Biology & Medicine
- Invited
- Data Source
  KAKENHI-PROJECT-16H05514
[Presentation] Pannexin 3は新骨形成制御因子である2017
- Author(s)
  石河真幸、 Geneva L. Williams、折本愛、半田慶介、山田吉彦、齋藤正寛
- Organizer
  結合組織学会
- Data Source
  KAKENHI-PROJECT-16K15844
[Presentation] ADAMTSL6βを介したMarfan症候群の解離性大動脈瘤発症機構の解析2017
- Author(s)
  折本愛、二木正晴、石河真幸、半田慶介、齋藤正寛
- Organizer
  第146回保存学会日本歯科保存学会春季学術大会2017年6月9日
- Data Source
  KAKENHI-PROJECT-16K15844
[Presentation] Pannexin 3 is a new regulator for bone formation2017
- Author(s)
  Masaki Ishikawa
- Organizer
  The 49th Annual Meeting of the Japanese Society for Matrix Biology & Medicine
- Invited
- Data Source
  KAKENHI-PROJECT-16H05514
[Presentation] The role of gap junctin proteins in skeletal biology : points of view from Pannexin 3 and Connexin 432017
- Author(s)
  Masaki ishikawa
- Organizer
  Consortium of Biological Sciences 2017
- Invited
- Data Source
  KAKENHI-PROJECT-16H05514
[Presentation] Pannexin 3 and Connexion 43 regulate skeletal formation through their distinct expression patterns and functions.2016
- Author(s)
  Masaki Ishikawa, Geneva L. Williams, Tomoko Ikeuchi, Kiyoshi Sakai1, Satoshi Fukumoto, and Yoshihiko Yamada
- Organizer
  Bones & Teeth Gordon Research conferences.
- Place of Presentation
  Texas, USA
- Year and Date
  2016-02-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06042
[Presentation] ADAMTSL6β accelerated ADAMTS4 activity to enhance DAA in MFS.2016
- Author(s)
  Ai Orimoto, Masaharu Futagi, Masaki Ishikawa, Keisuke Handa, Masahiro Saito
- Organizer
  IADR
- Place of Presentation
  Seoul, South Korea
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15844
[Presentation] Cellular communication regulates hard tissue development. “ Pannexin 3, a new member of gap junction protein family modulates skeletal development via distinct functions from Connexin43. ”2016
- Author(s)
  Masaki Ishikawa
- Organizer
  第10回アジア小児歯科学会〔10th Biennial Conference of the Pediatric Dentistry Association of Asia(PDAA)〕および第54回日本小児歯科学会(JSPD)
- Place of Presentation
  東京　東京ドームホテル
- Year and Date
  2016-05-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06042
[Presentation] ギャップジャンクション蛋白Panx3による骨形成機構の解明2016
- Author(s)
  石河　真幸
- Organizer
  口腔医科学フロンティア研究会
- Place of Presentation
  愛媛大学　校友会館
- Year and Date
  2016-02-27
- Invited
- Data Source
  KAKENHI-PROJECT-15H06042
[Presentation] 新規歯科再生医療の実現化への挑戦：Pannexin 3を用いた硬組織再生医療の開発2015
- Author(s)
  石河真幸、折本　愛、二木　正晴、半田　慶介、齋藤正寛
- Organizer
  東北大学歯学会
- Place of Presentation
  Sendai, 東北大学歯学部B１講義室
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-15H06042
[Presentation] Pannexin 3 functions as an ER Ca2+ channel, hemichannel, and gap junction to promote osteoblast differentiation.2015
- Author(s)
  Masaki Ishikawa, Masahiro Saito
- Organizer
  143th General Session & Exhibition of J. Conserv.
- Place of Presentation
  Tokyo, 文京シビックホール
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-15H06042
[Presentation] Pannexin 3 is a new regulator that inhibits osteoprogenitor proliferation and susquently promotes differentiation to osteoblasts2015
- Author(s)
  Masaki Ishikawa, Williams Geneva, Satoshi Fukumoto, and Yoshihiko Yamada
- Organizer
  General Session & Exhibition of Biochemistry and Molecular Biology
- Place of Presentation
  Kobe, 神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H06042

1. Saito Masahiro (40215562)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 福本敏 (30264253)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. YAMADA AYA (40295085)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 犬塚博之 (20335863)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 阪井丘芳 (90379082)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 保住建太郎 (10453804)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 福島秀文 (70412624)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 吉田恭子 (00242967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YAMADA yoshihiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 折本愛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 斎藤正寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
12. 吉崎恵悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 半田慶介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Masaki Ishikawa 石河 真幸

石河 真幸 イシカワ マサキ

Research Projects

Research Products

Co-Researchers

メカノセンサー象牙芽細胞の咀嚼刺激受容と脳活性Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pannexin 3 provides bone marrow niche for B- and T cell differentiation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Anti-locomotive syndrome by regulating Pannexin 3 function(Fostering Joint International Research)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of growth factor - intercellular communication during dental epithelial and mesenchymal cell differentiation.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel diagnostic technology for marfan syndrome using periodontal tissue

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The development of anti-inflammatory and regenerative medicine for periodontitis: application of Pannexin 3 signaling pathways.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pannexin3の機能を応用した新骨再生療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

歯髄幹細胞維持に必要な微小環境の同定と再生医療への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

幹細胞を利用した新歯内治療法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Pannexin 3 regulates skin development via Epiprofin2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pannexin 3 ER Ca2+ channel gating is regulated by phosphorylation at the Serine 68 residue in osteoblast differentiation2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fibrillin-1 insufficiency alters periodontal wound healing failure in a mouse model of Marfan syndrome.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pannexin-3 Deficiency Delays Skin Wound Healing in Mice due to Defects in Channel Functionality2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metal ions from S‐PRG filler have the potential to prevent periodontal disease2017

Masaki Ishikawa 石河真幸

石河真幸イシカワマサキ