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Endo Satoshi  遠藤 智史

… Alternative Names

ENDO Satoshi  遠藤 智史

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Researcher Number 60433207
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-0578-9672
Affiliation (Current) 2025: 岐阜大学, 大学院連合創薬医療情報研究科, 准教授
2025: 岐阜薬科大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help 2024: 岐阜大学, 大学院連合創薬医療情報研究科, 准教授
2019 – 2023: 岐阜薬科大学, 薬学部, 准教授
2017 – 2018: 岐阜薬科大学, 薬学部, 講師
2010 – 2017: 岐阜薬科大学, 薬学部, 助教
2007 – 2009: Gifu Pharmaceutical University, 薬学部, 助手
Review Section/Research Field
Principal Investigator
Drug development chemistry / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 37030:Chemical biology-related / Urology / General pharmacology / Biological pharmacy
Except Principal Investigator
Drug development chemistry / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
Keywords
Principal Investigator
構造活性相関 / 抗がん剤耐性 / 抗癌剤耐性克服 / 抗癌剤 / AKR1B10 / アルドケト還元酵素 / アルドーケト還元酵素 / プロテオスタシス / アミロイド線維 / 阻害剤創製 … More / 泌尿器がん / 去勢抵抗性前立腺がん / Atg4B / がん / オートファジー阻害剤 / 前立腺がん / オートファジー / 創薬科学 / Nrf2 / 抗癌剤耐性化 / アパルタミド / AKR1C3 / 去勢抵抗性前立腺癌 / 阻害選択性の向上 / 構造安定性低下 / SNPs / 分子モデリング / SNP / 制癌薬 / 抗癌剤耐性抑制薬 / aldo-keto reductases / 癌 / イソプレノイド / 酵素 / 構造機能相関 / 9,10-phenanthrenequinone / 酸化ストレス / カルボニルストレス / カルボニル還元酵素 … More
Except Principal Investigator
LC3-GST cleavage assay / システインプロテアーゼ / オートファジー / 構造―活性相関 / in silicoスクリーニング / Atg4B阻害剤 / オートファジー阻害剤 / バイオマーカー / クローディン / 細胞局在 / Mgチャネル / 低Mg血症 / 医薬品設計 / アルドース還元酵素 / 高次構造 / 阻害剤 / 抗癌剤耐性 / 制癌剤 / アルドーケト還元酵素 / ヒドロキシステロイド脱水素酵素 / 医薬品化学・医薬分子設計 Less
  • Research Projects

    (10 results)
  • Research Products

    (147 results)
  • Co-Researchers

    (14 People)
  •  アミロイド線維の戦略的蓄積による画期的がん治療戦略の確立Principal Investigator

    • Principal Investigator
      遠藤 智史
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Gifu University
  •  Research and development of autophagy-specific inhibitors

    • Principal Investigator
      豊岡 尚樹
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
    • Research Institution
      University of Toyama
  •  Reconsidering the significance of autophagy in urological cancer and drug discoveryPrincipal Investigator

    • Principal Investigator
      Endo Satoshi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 37030:Chemical biology-related
    • Research Institution
      Gifu Pharmaceutical University
  •  Development of a multi-targeted castration-resistant prostate cancer drug for clinical applicationPrincipal Investigator

    • Principal Investigator
      Endo Satoshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Gifu Pharmaceutical University
  •  Establishment of the basis for evolutional drug development toward avoidance of hypomagnesemia

    • Principal Investigator
      IKARI AKIRA
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Drug development chemistry
    • Research Institution
      Gifu Pharmaceutical University
  •  Development of novel anticancer agents targeting survival strategy of cancer cellsPrincipal Investigator

    • Principal Investigator
      Endo Satoshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Gifu Pharmaceutical University
  •  Development of novel anticancer drugs targeting for controlling the function and expression of oxidative stress-induced proteinPrincipal Investigator

    • Principal Investigator
      ENDO Satoshi
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Drug development chemistry
    • Research Institution
      Gifu Pharmaceutical University
  •  DEVELOPMENT OF ANTITUMOR DRUGS TARGETING TUMOR MARKERALDO-KETO REDUCTASES

    • Principal Investigator
      HARA Akira
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Gifu Pharmaceutical University
  •  Development of antitumor agents targeting for prenoid-metabolizing enzymesPrincipal Investigator

    • Principal Investigator
      ENDO Satoshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General pharmacology
    • Research Institution
      Gifu Pharmaceutical University
  •  Elucidation of defense mechanism against carbonyl stress by reductases for carbonyl compoundsPrincipal Investigator

    • Principal Investigator
      ENDO Satoshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (Start-up)
    • Research Field
      Biological pharmacy
    • Research Institution
      Gifu Pharmaceutical University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Patent

  • [Journal Article] Artepillin C overcomes apalutamide resistance through blocking androgen signaling in prostate cancer cells2023

    • Author(s)
      Ota Atsumi、Kawai Mina、Kudo Yudai、Segawa Jin、Hoshi Manami、Kawano Shinya、Yoshino Yuta、Ichihara Kenji、Shiota Masaki、Fujimoto Naohiro、Matsunaga Toshiyuki、Endo Satoshi、Ikari Akira
    • Journal Title

      Archives of Biochemistry and Biophysics

      Volume: 735 Pages: 109519-109519

    • DOI

      10.1016/j.abb.2023.109519

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K05751
  • [Journal Article] Discovery and Structure-Based Optimization of Novel Atg4B Inhibitors for the Treatment of Castration-Resistant Prostate Cancer2022

    • Author(s)
      Kudo Yudai、Endo Satoshi、Fujita Mei、Ota Atsumi、Kamatari Yuji O.、Tanaka Yoshimasa、Ishikawa Takeshi、Ikeda Hayato、Okada Takuya、Toyooka Naoki、Fujimoto Naohiro、Matsunaga Toshiyuki、Ikari Akira
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 65 Issue: 6 Pages: 4878-4892

    • DOI

      10.1021/acs.jmedchem.1c02113

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K12129, KAKENHI-PROJECT-20K05751, KAKENHI-PROJECT-20H04285
  • [Journal Article] Correction to “Discovery and Structure-Based Optimization of Novel Atg4B Inhibitors for the Treatment of Castration-Resistant Prostate Cancer”2022

    • Author(s)
      Kudo Yudai、Endo Satoshi、Fujita Mei、Ota Atsumi、Kamatari Yuji O.、Tanaka Yoshimasa、Ishikawa Takeshi、Ikeda Hayato、Okada Takuya、Toyooka Naoki、Fujimoto Naohiro、Matsunaga Toshiyuki、Ikari Akira
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 65 Issue: 11 Pages: 8062-8063

    • DOI

      10.1021/acs.jmedchem.2c00749

    • Data Source
      KAKENHI-PROJECT-20K05751
  • [Journal Article] Targeting Nrf2-antioxidant signaling reverses acquired cabazitaxel resistance in prostate cancer cells.2021

    • Author(s)
      Satoshi Endo, Mina Kawai, Manami Hoshi, Jin Segawa, Mei Fujita, Takuo Matsukawa, Naohiro Fujimoto, Toshiyuki Matsunaga, Akira Ikari
    • Journal Title

      Journal of Biochemistry

      Volume: - Issue: 1 Pages: 89-96

    • DOI

      10.1093/jb/mvab025

    • NAID

      40022721819

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K05751
  • [Journal Article] Human dehydrogenase/reductase SDR family member 11 (DHRS11) and aldo-keto reductase 1C isoforms in comparison: Substrate and reaction specificity in the reduction of 11-keto-C19-steroids2020

    • Author(s)
      Endo Satoshi、Morikawa Yoshifumi、Kudo Yudai、Suenami Koichi、Matsunaga Toshiyuki、Ikari Akira、Hara Akira
    • Journal Title

      The Journal of Steroid Biochemistry and Molecular Biology

      Volume: 199 Pages: 105586-105586

    • DOI

      10.1016/j.jsbmb.2020.105586

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11151
  • [Journal Article] Rabbit dehydrogenase/reductase SDR family member 11 (DHRS11): Its identity with acetohexamide reductase with broad substrate specificity and inhibitor sensitivity, different from human DHRS112019

    • Author(s)
      Endo Satoshi、Miyagi Namiki、Matsunaga Toshiyuki、Ikari Akira
    • Journal Title

      Chemico-Biological Interactions

      Volume: 305 Pages: 12-20

    • DOI

      10.1016/j.cbi.2019.03.026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11151
  • [Journal Article] Elevation of sensitivity to anticancer agents of human lung adenocarcinoma A549 cells by knockdown of claudin-2 expression in monolayer and spheroid culture models2018

    • Author(s)
      Maruhashi Ryohei、Akizuki Risa、Sato Tomonari、Matsunaga Toshiyuki、Endo Satoshi、Yamaguchi Masahiko、Yamazaki Yasuhiro、Sakai Hideki、Ikari Akira
    • Journal Title

      Biochimica et Biophysica Acta

      Volume: 1865 Issue: 3 Pages: 470-479

    • DOI

      10.1016/j.bbamcr.2017.12.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04657, KAKENHI-PROJECT-17H05030
  • [Journal Article] Caffeic acid phenethyl ester down-regulates claudin-2 expression at the transcriptional and post-translational levels and enhances chemosensitivity to doxorubicin in lung adenocarcinoma A549 cells2018

    • Author(s)
      Sonoki Hiroyuki、Tanimae Asami、Furuta Takumi、Endo Satoshi、Matsunaga Toshiyuki、Ichihara Kenji、Ikari Akira
    • Journal Title

      Journal of Nutritional Biochemistry

      Volume: 56 Pages: 205-214

    • DOI

      10.1016/j.jnutbio.2018.02.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Journal Article] Decrease in paracellular permeability and chemosensitivity to doxorubicin by claudin-1 in spheroid culture models of human lung adenocarcinoma A549 cells2018

    • Author(s)
      Akizuki Risa、Maruhashi Ryohei、Eguchi Hiroaki、Kitabatake Kazuki、Tsukimoto Mitsutoshi、Furuta Takumi、Matsunaga Toshiyuki、Endo Satoshi、Ikari Akira
    • Journal Title

      Biochimica et Biophysica Acta

      Volume: 1865 Issue: 5 Pages: 769-780

    • DOI

      10.1016/j.bbamcr.2018.03.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Journal Article] Chlorpheniramine Increases Paracellular Permeability to Marker Fluorescein Lucifer Yellow Mediated by Internalization of Occludin in Murine Colonic Epithelial Cells2017

    • Author(s)
      Manabe Aya、Furukawa Chisa、Endo Satoshi、Marunaka Kana、Nishiyama Tsubasa、Fujii Naoko、Tabuchi Yoshiaki、Matsunaga Toshiyuki、Ikari Akira
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 40 Issue: 8 Pages: 1299-1305

    • DOI

      10.1248/bpb.b17-00244

    • NAID

      130005876269

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Journal Article] Down-regulation of claudin-2 expression and proliferation by epigenetic inhibitors in human lung adenocarcinoma A549 cells2017

    • Author(s)
      Hichino A, Okamoto M, Taga S, Akizuki R, Endo S, Matsunaga T, Ikari A
    • Journal Title

      Journal of Biological Chemistry

      Volume: 292 Issue: 6 Pages: 2411-2421

    • DOI

      10.1074/jbc.m116.762807

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Journal Article] Claudin-5, -7, and -18 suppress proliferation mediated by inhibition of phosphorylation of Akt in human lung squamous cell carcinoma2017

    • Author(s)
      Akizuki R, Shimobaba S, Matsunaga T, Endo S, Ikari A
    • Journal Title

      Biochimica et Biophysica Acta

      Volume: 1864 Issue: 2 Pages: 293-302

    • DOI

      10.1016/j.bbamcr.2016.11.018

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Journal Article] Kaempherol and Luteolin Decrease Claudin-2 Expression Mediated by Inhibition of STAT3 in Lung Adenocarcinoma A549 Cells2017

    • Author(s)
      Sonoki Hiroyuki、Tanimae Asami、Endo Satoshi、Matsunaga Toshiyuki、Furuta Takumi、Ichihara Kenji、Ikari Akira
    • Journal Title

      Nutrients

      Volume: 9 Issue: 6 Pages: 597-597

    • DOI

      10.3390/nu9060597

    • NAID

      120006333890

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Journal Article] Fatty Acids and CoA Derivatives as Inhibitors of Human Carbonyl Reductase 12017

    • Author(s)
      Akira Hara, Satoshi Endo, Toshiyuki Matsunaga, Ossama El-Kabbani, Takeshi Miura, Toru Nishinaka and Tomoyuki Terada
    • Journal Title

      Biochem. Pharmacol.

      Volume: 印刷中 Pages: 185-192

    • DOI

      10.1016/j.bcp.2017.04.023

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460149
  • [Journal Article] Instability of C154Y variant of aldo-keto reductase 10.1038/s41598-017-00710-x1C32017

    • Author(s)
      Satoshi Endo, Sayaka Takada, Ryo P. Honda, Kathrin Muller, Jochen H. Weishaupt, Peter M. Andersen, Albert C. Ludolph, Yuji O. Kamatari, Toshiyuki Matsunaga, Kazuo Kuwata, Ossama El-Kabbani, Akira Ikari
    • Journal Title

      Chemico-Biological Interactions

      Volume: S0009-2797(16) Pages: 194-202

    • DOI

      10.1016/j.cbi.2016.12.018

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26291011, KAKENHI-PROJECT-26460149, KAKENHI-PROJECT-15K07024
  • [Journal Article] The RING finger- and PDZ domain-containing protein PDZRN3 controls localization of the Mg2+ regulator claudin-16 in renal tube epithelial cells.2017

    • Author(s)
      Marunaka Kana、Furukawa Chisa、Fujii Naoko、Kimura Toru、Furuta Takumi、Matsunaga Toshiyuki、Endo Satoshi、Hasegawa Hajime、Anzai Naohiko、Yamazaki Yasuhiro、Yamaguchi Masahiko、Ikari Akira
    • Journal Title

      Journal of Biological Chemistry

      Volume: 292 Issue: 31 Pages: 13034-13044

    • DOI

      10.1074/jbc.m117.779405

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04657, KAKENHI-PROJECT-17H05030
  • [Journal Article] Up-regulation of claudin-2 expression by aldosterone in colonic epithelial cells of mice fed with NaCl-depleted diets2017

    • Author(s)
      Furukawa Chisa、Ishizuka Noriko、Hayashi Hisayoshi、Fujii Naoko、Manabe Aya、Tabuchi Yoshiaki、Matsunaga Toshiyuki、Endo Satoshi、Ikari Akira
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1

    • DOI

      10.1038/s41598-017-12494-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Journal Article] Up-regulation of transient receptor potential melastatin 6 channel expression by tumor necrosis factor-α in the presence of epidermal growth factor receptor tyrosine kinase inhibitor2016

    • Author(s)
      Furukawa C, Fujii N, Manabe A, Matsunaga T, Endo S, Hasegawa H, Ito Y, Yamaguchi M, Yamazaki Y, Ikari A
    • Journal Title

      Journal of Cellular Physiology

      Volume: 印刷中 Issue: 10 Pages: 2841-2850

    • DOI

      10.1002/jcp.25709

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04657, KAKENHI-PROJECT-17H05030
  • [Journal Article] Claudin-18 inhibits cell proliferation and motility mediated by inhibition of phosphorylation of PDK1 and Akt in human lung adenocarcinoma A549 cells2016

    • Author(s)
      Shun Shimobaba, Saeko Taga, Risa Akizuki, Asami Hichino, Satoshi Endo, Toshiyuki Matsunaga, Ryo Watanabe, Masahiko Yamaguchi, Yasuhiro Yamazaki, Junko Sugatani, Akira Ikari
    • Journal Title

      Biochimica et Biophysica Acta

      Volume: 1863 Issue: 6 Pages: 1170-1178

    • DOI

      10.1016/j.bbamcr.2016.02.015

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04657, KAKENHI-PROJECT-26860041
  • [Journal Article] Hypotonic stress-induced down-regulation of claudin-1 and -2 mediated by dephosphorylation and clathrin-dependent endocytosis in renal tubular epithelial cells2016

    • Author(s)
      Fujii N, Matsuo Y, Matsunaga T, Endo S, Sakai H, Yamaguchi M, Yamazaki Y, Sugatani J, Ikari A
    • Journal Title

      Journal of Biological Chemistry

      Volume: 291 Issue: 47 Pages: 24787-24799

    • DOI

      10.1074/jbc.m116.728196

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04657, KAKENHI-PROJECT-15K15029, KAKENHI-PROJECT-26860041
  • [Journal Article] Clathrin-dependent endocytosis of claudin-2 by DFYSP peptide causes lysosomal damage in lung adenocarcinoma A549 cells.2015

    • Author(s)
      Ikari A, Taga S, Watanabe R, Sato T, Shimobaba S, Sonoki H, Endo S, Matsunaga T, Sakai H, Yamaguchi M, Yamazaki Y, Sugatani J.
    • Journal Title

      Biochim Biophys Acta.

      Volume: 1848 Issue: 10 Pages: 2326-2336

    • DOI

      10.1016/j.bbamem.2015.07.003

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15029, KAKENHI-PROJECT-15H04657, KAKENHI-PROJECT-25293047
  • [Journal Article] Characterization of hamster NAD+-dependent 3(17)β-hydroxysteroid dehydrogenase belonging to the aldo-keto reductase 1C subfamily2015

    • Author(s)
      Satoshi Endo, Misato Noda, Akira Ikari, Ossama El-Kabbani, Akira Hara and Toshiyuki Matsunaga
    • Journal Title

      J. Biochem.

      Volume: 158 Pages: 425-434

    • NAID

      40020647066

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460149
  • [Journal Article] Structure-activity relationships of flavonoids for carbonyl reductase 1 (CBR1) inhibition2015

    • Author(s)
      Arai, Y., Endo, S., Miyagi, N., Abe, N., Miura, T., Nishinaka, T., Terada, T., Oyama, M., Goda, H., El-Kabbani, O., Hara, A., Matsunaga, T. and Ikari, A.
    • Journal Title

      Fitoterapia

      Volume: 101 Pages: 51-56

    • DOI

      10.1016/j.fitote.2014.12.010

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460149
  • [Journal Article] Synthesis of 8-hydroxy-2-iminochromene derivatives as selective and potent inhibitors of human carbonyl reductase 12015

    • Author(s)
      Dawei Hu, Namiki Miyagi, Yuki Arai, Hiroaki Oguri, Takeshi Miura, Toru Nishinaka, Tomoyuki Terada, Hiroaki Gouda, Ossama El-Kabbani, Shuang, Xia, Naoki Toyooka, Akira Hara, Toshiyuki Matsunaga, Akira Ikari, Satoshi Endo
    • Journal Title

      Org. Biomol. Chem.

      Volume: 13 Pages: 7487-7499

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460149
  • [Journal Article] Cloning and characterization of four rabbit aldo-keto reductases featuring broad substrate specificity for xenobiotic and endogenous carbonyl compounds: Their relationship with multiple forms of drug ketone reductases2014

    • Author(s)
      Satoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Yasuo Bunai, Akira Hara, Yukio Kitade
    • Journal Title

      Drug Metab. Dispos.

      Volume: 42 Issue: 4 Pages: 803-812

    • DOI

      10.1124/dmd.113.056044

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790114
  • [Journal Article] Synthesis and structure-activity relationship of 2-phenyliminochromene derivatives as inhibitors for AKR1B102013

    • Author(s)
      Satoshi Endo, Dawei HU, Miho Suyama, Toshiyuki Matsunaga, Kenji Sugimoto, Yuji Matsuya, Ossama El-Kabbani, Kazuo Kuwata, Akira Hara, Yukio Kitade, Naoki Toyooka
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 21(21) Issue: 21 Pages: 6378-6384

    • DOI

      10.1016/j.bmc.2013.08.059

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23370068, KAKENHI-PROJECT-24570180, KAKENHI-PROJECT-24790114, KAKENHI-PROJECT-25460068
  • [Journal Article] Modulation of activity and inhibitor sensitivity of rabbit aldose reductase-like protein (AKR1B19) by oxidized glutathione and SH-reagents2013

    • Author(s)
      Satoshi Endo
    • Journal Title

      Chemico-Biological Interactions

      Volume: 202 Issue: 1-3 Pages: 146-152

    • DOI

      10.1016/j.cbi.2012.11.026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22570044, KAKENHI-PROJECT-22790074, KAKENHI-PROJECT-24790114
  • [Journal Article] Rabbit 3-hydroxyhexobarbital dehydrogenase is a NADPH-preferring reductase with broad substrate specificity for ketosteroids, prostaglandin D2, and other endogenous and xenobiotic carbonyl compounds2013

    • Author(s)
      Satoshi Endo, Toshiyuki Matsunaga, Atsuko Matsumoto, Yuki Arai, Satoshi Ohno, Ossama El-Kabbani, Kazuo Tajima, Yukio Kitade, Yasuo Bunai, Shigeru Yamano, and Akira Hara
    • Journal Title

      Biochem. Pharmacol.

      Volume: 86 Issue: 9 Pages: 1366-1375

    • DOI

      10.1016/j.bcp.2013.08.024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790114, KAKENHI-PROJECT-25460068
  • [Journal Article] Characterization of a rabbit morphine 6-dehydrogenase and its two isoforms which function as NAD+-dependent 3α(17β)- hydroxysteroid dehydrogenases2012

    • Author(s)
      Satoshi Endo, Toshiyuki Matsunaga, Airi Fujimoto, Sho Kumada, Yuki Arai, Yoko Miura, Hiroshige Mikamo, Ossama El-Kabbani, Shigeru Yamano, Munekazu Iinuma, Akira Hara
    • Journal Title

      Arch. Biochem. Biophys

      Volume: Vol.529、No.2 Issue: 2 Pages: 131-139

    • DOI

      10.1016/j.abb.2012.11.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790114
  • [Journal Article] Inhibition of Human Aldose Reductase-like Protein (AKR1B10) byα- andγ-Mangostins, Major Components of Pericarps of Mangosteen、Biol2012

    • Author(s)
      Midori Soda, Satoshi Endo, Toshiyuki Matsunaga, Hai-Tao Zhao, Ossama El-Kabbani, Munekazu Iinuma, Keiko Yamamura, and Akira Hara
    • Journal Title

      Pharm. Bull.

      Volume: Vol.35、No.11 Pages: 2075-2080

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790114
  • [Journal Article] Design, synthesis and evaluation of caffeic acid phenethyl ester-based inhibitors targeting a selectivity pocket in the active site of human aldo-keto reductase 1B102012

    • Author(s)
      Soda M, Hu D, Endo S,他
    • Journal Title

      Eur. J. Med.Chem.

      Volume: 48 Pages: 321-329

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590102
  • [Journal Article] Selective inhibition of human type-5 17β-hydroxysteroid dehydrogenase (AKR1C3) by baccharin, a component of Brazilian propolis2012

    • Author(s)
      Endo S, Matsunaga T,他
    • Journal Title

      J. Nat. Prod

      Volume: 75 Pages: 716-721

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590102
  • [Journal Article] Pathophysiological roles of aldo-keto reductases (AKR1C1 and AKR1C3) in development of cisplatin resistance in human colon cancers2012

    • Author(s)
      Matsunaga T, Hojo A, Yamane Y, Endo S, El-Kabbani O, Hara A
    • Journal Title

      Chem. Biol. Interact

      Volume: 202 Issue: 1-3 Pages: 234-242

    • DOI

      10.1016/j.cbi.2012.09.024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590102, KAKENHI-PROJECT-22790074
  • [Journal Article] Aldo-keto reductase 1B10 and its role in proliferation capacity of drug-resistant cancers2012

    • Author(s)
      Matsunaga T, Wada Y, Endo S, Soda M, El-Kabbani O, Hara A
    • Journal Title

      Front. Pharmacol

      Volume: 3 Pages: 5-11

    • DOI

      10.3389/fphar.2012.00005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590102, KAKENHI-PROJECT-22790074
  • [Journal Article] Design, syn thesis and evaluation of caffeic ac id phenethyl ester-based inhibitors targeting a selectivity pocket in the active site of human aldo-keto reductase 1B102012

    • Author(s)
      Midori Soda, Dawei Hu, Satoshi Endo, Mayuko Takemura, Jie Li, Ryogo Wa da, Syohei Ifuku, Hai-Tao Zhao, Oss ama El-Kabbani, Shozo Ohta, Keiko Y amamura, Naoki Toyooka, Akira Hara, and Toshiyuki Matsunaga
    • Journal Title

      Eur. J. Med. Chem.

      Volume: 48 Pages: 321-329

    • DOI

      10.1016/j.ejmech.2011.12.034

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790245, KAKENHI-PROJECT-22590102, KAKENHI-PROJECT-22790074
  • [Journal Article] Inhibition of Human Aldose Reductase-Like Protein (AKR1B10) by α- and γ-Mangostins, Major Components of Pericarps of Mangosteen2012

    • Author(s)
      Soda M, Endo S
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 35 Issue: 11 Pages: 2075-2080

    • DOI

      10.1248/bpb.b12-00538

    • NAID

      130001872266

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590102, KAKENHI-PROJECT-22790074
  • [Journal Article] Inhibition of Human Aldose Reductase-like Protein (AKR1B10) by α- and γ-Mangostins, Major Components of Pericarps of Mangosteen2012

    • Author(s)
      Midori Soda, Satoshi Endo, Toshiyuki Matsunaga, Hai-Tao Zhao, Ossama El-Kabbani, Munekazu Iinuma, Keiko Yamamura, and Akira Hara
    • Journal Title

      Biol. Pharm. Bull.

      Volume: 35 Pages: 2075-2080

    • NAID

      130001872266

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790114
  • [Journal Article] Selective inhibition of human type-5 17β-hydroxysteroid dehydrogenase(AKR1C3) by bacchari n, a component of brazilian propolis2012

    • Author(s)
      Satoshi Endo, Toshiyuki Matsunaga, Ayano Kanamori, Youko Otsuji, Hirok o Nagai, Krithika Sundaram, Ossama El-Kabbani, Naoki Toyooka, Shozo O hta and A kira
    • Journal Title

      J. Nat. Prod.

      Volume: 75 Issue: 4 Pages: 716-721

    • DOI

      10.1021/np201002x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790245, KAKENHI-PROJECT-22590102, KAKENHI-PROJECT-22790074
  • [Journal Article] Roles of rat and human aldo-keto reductases in metabolism of farnesol and geranylgeraniol2011

    • Author(s)
      Endo S, Matsunaga T, 他
    • Journal Title

      Chem. Biol. Interact

      Volume: 191 Pages: 261-268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590102
  • [Journal Article] Roles of rat and human aldo-k eto reductases in metabolism of farne sol and geranylgeraniol2011

    • Author(s)
      Satoshi Endo, Toshiyuki Matsunaga, Ch isato Ohta, Midori Soda, Ayano Kanam ori, Yukio Kitade, Satoshi Ohno, Kaz uo Tajima, Ossama El-Kabbani and Akir a Hara
    • Journal Title

      Chem. Biol. Interact.

      Volume: 191 Issue: 1-3 Pages: 261-268

    • DOI

      10.1016/j.cbi.2010.12.017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790245, KAKENHI-PROJECT-22590102, KAKENHI-PROJECT-22790074
  • [Journal Article] Probing the Inhi bitor Selectivity Pocket of Human 20α-Hydroxysteroid Dehydrogenase(AKR1 C1) with X-Ray Crystallography and Si te-Directed Mutagenesis2011

    • Author(s)
      Ossama El-Kabbani, Urmi Dhagat, Midor i Soda, Satoshi Endo, Toshiyuki Matsu naga and Akira Hara
    • Journal Title

      Bioorg. Med. Chem. Lett.

      Volume: 21 Issue: 8 Pages: 2564-2567

    • DOI

      10.1016/j.bmcl.2011.01.076

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790245, KAKENHI-PROJECT-22590102
  • [Journal Article] Sele ctive Inhibition of the Tumor Marker Aldo-keto Reductase Family Member 1B1 0 by Oleanolic Acid2011

    • Author(s)
      Mayuko Takemura, Satoshi Endo, Toshiy uki Matsunaga, Midori Soda, Hai-Tao Zhao, Ossama El-Kabbani, Kazuo Tajima, Munekazu Iimuma, and Akira Hara
    • Journal Title

      J. Nat. Prod.

      Volume: 74 Issue: 5 Pages: 1201-1206

    • DOI

      10.1021/np200118q

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790245, KAKENHI-PROJECT-22590102, KAKENHI-PROJECT-22790074
  • [Journal Article] Chromene-3-carboxamide derivatives discovered from virtual screening as potent inhibitors of the tumour maker, AKR1B102010

    • Author(s)
      Satoshi Endo, Toshiyuki Matsunaga, Kazuo Kuwata, Hai-Tao Zhao, Ossama El-Kabbani, Yukio Kitade and Akira Hara
    • Journal Title

      Bioorg. Med. Chem.

      Volume: 18 Issue: 7 Pages: 2485-2490

    • DOI

      10.1016/j.bmc.2010.02.050

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790245
  • [Journal Article] Selective inhibition of the tumor marker AKR1B10 by anti-inflammatory N-phenylanthranilic acids and glycyrrhetic acid.2010

    • Author(s)
      S.Endo, 他6名
    • Journal Title

      Biol Pharm Bull.

      Volume: 33 Pages: 886-890

    • NAID

      130000248053

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590102
  • [Journal Article] Selectivity Determinants of Inhibitor Binding to the Tumour Marker Human Aldose Reductase-Like Protein(AKR1B10) Discovered from Molecular Docking and Database Screening2010

    • Author(s)
      Hi-Tai Zhao, Midori Soda, Satoshi Endo, Akira Hara, Ossama El-Kabbani
    • Journal Title

      Eur. J. Med. Chem.

      Volume: 45 Issue: 9 Pages: 4354-4357

    • DOI

      10.1016/j.ejmech.2010.05.032

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790245
  • [Journal Article] Chromene-3-carboxamide derivatives discovered from virtual screening as -potent inhibitors of the tumour maker, AKR1B102010

    • Author(s)
      Satoshi Endo
    • Journal Title

      Bioorg.Med.Chem. 18

      Pages: 2010-2010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790245
  • [Journal Article] Selective Inhibition of the Tumor Marker AKR1B10 by Antiinflammatory N-Phenylanthranilic Acids and Glycyrrhetic Acid2010

    • Author(s)
      Satoshi Endo, Toshiyuki Matsunaga, Midori Soda, Kazuo Tajima, Hi-Tai Zhao, Ossama, El-Kabbani and Akira Hara
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 33 Issue: 5 Pages: 886-890

    • DOI

      10.1248/bpb.33.886

    • NAID

      130000248053

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790245, KAKENHI-PROJECT-22590102
  • [Journal Article] Studies on a Tyr residue critical for the binding of coenzyme and substrate in mouse 3(17)α-hydroxysteroid dehydrogenase (AKR1C21)2010

    • Author(s)
      U.Dhagat, S.Endo, H.Mamiya, A.Hara, O.El-Kabbani
    • Journal Title

      Acta Crystallogr.D Biol.Crystallogr.

      Volume: 66 Pages: 198-204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590102
  • [Journal Article] Selective Inhibition of the Tumor Marker AKR1B10 by Antiinflammatory N-Phenylanthranilic Acids and Glycyrrhetic Acid.2010

    • Author(s)
      Satoshi Endo
    • Journal Title

      Biol.Pharm.Bull.

      Volume: 33 Pages: 886-890

    • NAID

      130000248053

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790245
  • [Journal Article] Factorizing the role of a critical leucine residue in the binding of substrate to human 20α-hydroxysteroid dehydrogenase (AKR1C1).2010

    • Author(s)
      U.Dhagat, S.Endo, M.Soda, A.Hara, O.El-Kabbani
    • Journal Title

      Bioorg.Med.Chem.Lett.

      Volume: 20 Pages: 5274-5276

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590102
  • [Journal Article] Potent and selective inhibition of the tumor marker AKR1B10 by bisdemethoxycurcumin : Probing the active site of the enzyme with molecular modeling and site-directed mutagenesis2009

    • Author(s)
      Toshiyuki Matsunaga, Satoshi Endo, Midori Soda, Hai-Tao Zhao, Ossama El-Kabbani, Kazuo Tajima, Akira Hara
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 389 Issue: 1 Pages: 128-132

    • DOI

      10.1016/j.bbrc.2009.08.107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790245
  • [Journal Article] Characterization of a rat NADPH-dependent aldo-keto reductase (AKR1B13) induced by oxidative stress.2009

    • Author(s)
      Satoshi Endo
    • Journal Title

      Chem. Biol. Interact. 176

      Pages: 151-157

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890180
  • [Journal Article] Structure-Guided Design, Synthesis and Evaluation of Salicylic Acid-Based Inhibitors Targeting a Selectivity Pocket in the Active Site of Human 20α-Hydroxysteroid Dehydrogen ase(AKR1C1)2009

    • Author(s)
      Ossama El-Kabbani, Peter J. Scammells, Joshua Gosling, Urmi Dhagat, Satoshi Endo, Toshiyuki Matsunaga, Midori Soda and Akira Hara
    • Journal Title

      J. Med. Chem.

      Volume: 52 Issue: 10 Pages: 3259-3264

    • DOI

      10.1021/jm9001633

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790245
  • [Journal Article] Characterization of a rat NADPH-dependent aldo-keto reductase (AKR1B13) induced by oxidative stress2009

    • Author(s)
      Satoshi Endo, Toshiyuki Matsunaga, Hiroaki Mamiya, Akira Hara, Yukio Kitade, Kazuo Tajima, Ossama El-Kabbani
    • Journal Title

      Chem. Biol. Interact 176

      Pages: 151-157

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890180
  • [Journal Article] Kinetic studies of AKR1B10, human aldose reductase-like protein: Endo genous substrates and inhibition by steroids2009

    • Author(s)
      Satoshi Endo
    • Journal Title

      Arch.Biochem.Biophys. 487

      Pages: 1-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790245
  • [Journal Article] Kinetic studies of AKR1B10, human aldose reductase-like protein : Endogenous substrates and inhibition by steroids、Arch2009

    • Author(s)
      Satoshi Endo, Toshiyuki Matsunaga, Hiroaki Mamiya, Chisato Ohta, Midori Soda, Yukio Kitade, Kazuo Tajima, Hai-Tao Zhao, Ossama El-Kabbani, Akira Hara
    • Journal Title

      Arch. Biochem. Biophys.

      Volume: 487 Issue: 1 Pages: 1-9

    • DOI

      10.1016/j.abb.2009.05.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790245
  • [Journal Article] Characterization of human DHRS4: An inducible short-chain dehydrogenase/reductase enzyme with 3beta-hydroxysteroid dehydrogenase activity2008

    • Author(s)
      Toshiyuki Matsunaga, Satoshi Endo, Satoshi Maeda , Shuhei Ishikura, Kazuo Tajima, Nobutada Tanaka, Kazuo TNakamura, Yorishige Imamura, and Akira Hara
    • Journal Title

      Arch. Biochem. Biophys 477

      Pages: 339-347

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890180
  • [Journal Article] Human carbonyl reductase 4 is a mitochondrial NADPH-dependent quinone reductase2008

    • Author(s)
      Satoshi Endo, Toshiyuki Matsunaga, Yukio Kitade, Satoshi Ohno, Kazuo Tajima, Ossama El-Kabbani and Akira Hara
    • Journal Title

      Biochem. Biophys. Res. Commun 377

      Pages: 1326-1330

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890180
  • [Journal Article] Human carbonyl reductase 4 is a mitochondrial NADPH-dependent quinone reductase.2008

    • Author(s)
      Satoshi Endo
    • Journal Title

      Biochem. Biophys. Res. Commun. 377

      Pages: 1326-1330

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890180
  • [Journal Article] Enzymatic Characteristics of an Aldo-Keto Reductase Family Protein(AKR1C15)and its Localization in Rat Tissues2007

    • Author(s)
      Satoshi Endo
    • Journal Title

      Arch. Biochem. Biophys. 465

      Pages: 136-147

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890180
  • [Journal Article] Enzymatic characteristics of an aldo-keto reductase family protein(AKR1C15) and its localization in rat tissues2007

    • Author(s)
      Satoshi Endo, Toshiyuki Matsunaga, Kenji Horie, Kazuo Tajima, Yasuo Bunai, Vincenzo Carbone, Ossama El-Kabbani, Akira Hara
    • Journal Title

      Arch. Biochem. Biophys 465

      Pages: 136-147

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890180
  • [Journal Article] Characterization of rat and mouse NAD+-dependent 3alpha/17beta/20alpha-hydroxysteroid dehydrogenases and identification of substrate specificity determinants by site-directed mutagenesis2007

    • Author(s)
      Satoshi Endo, Masaharu Sanai, Kenji Horie, Toshiyuki Matsunaga, Syuhei Ishikura, KazuoTajima, Ossama El-Kabbani, and Akira Hara
    • Journal Title

      Arch. Biochem. Biophys 467

      Pages: 76-86

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890180
  • [Journal Article] Rat NAD+-dependent 3alpha-hydroxysteroid dehydrogenase (AKR1C17): A member of the aldo-keto reductase family highly expressed in kidney cytosol2007

    • Author(s)
      Masaharu Sanai, Satoshi Endo, Toshiyuki Matsunaga, Shuhei Ishikura, Kazuo Tajima, Ossama El-Kabbani and Akira Hara
    • Journal Title

      Arch. Biochem. Biophys 464

      Pages: 122-129

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890180
  • [Journal Article] Characterization of rat and mouse NAD+-dependent 3α/17β/20α-hydroxysteroid dehydrogenases and identification of substrate specificity determinants by site-directed mutagenesis2007

    • Author(s)
      Satoshi Endo
    • Journal Title

      Arch. Biochem. Biophys. 467

      Pages: 76-86

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890180
  • [Patent] オートファジー阻害剤2020

    • Inventor(s)
      遠藤智史、五十里彰、豊岡尚樹 、岡田卓哉、藤本直浩
    • Industrial Property Rights Holder
      遠藤智史、五十里彰、豊岡尚樹 、岡田卓哉、藤本直浩
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-20K05751
  • [Patent] AKR1C3選択的阻害剤及びその用途2018

    • Inventor(s)
      遠藤智史、松永俊之、五十里彰、豊岡尚樹、藤本直浩
    • Industrial Property Rights Holder
      岐阜市、富山大学、産業医科大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-17K11151
  • [Patent] AKR1B10阻害に基づく肺癌治療薬2016

    • Inventor(s)
      遠藤智史、松永俊之、五十里彰、豊岡尚樹、早川芳弘
    • Industrial Property Rights Holder
      岐阜市、富山大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016-08-15
    • Data Source
      KAKENHI-PROJECT-26460149
  • [Patent] AKR1C3阻害剤2013

    • Inventor(s)
      遠藤 智史、松永 俊之、豊岡 尚樹
    • Industrial Property Rights Holder
      岐阜市
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-149089
    • Filing Date
      2013-07-18
    • Data Source
      KAKENHI-PROJECT-24790114
  • [Patent] AKR1C3阻害剤2013

    • Inventor(s)
      遠藤智史、松永俊之、豊岡尚樹
    • Industrial Property Rights Holder
      岐阜市
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-149089
    • Filing Date
      2013-07-18
    • Data Source
      KAKENHI-PROJECT-24790114
  • [Presentation] オートファジーを標的とした抗がん剤耐性膵臓がん治療戦略の開発2023

    • Author(s)
      工藤 優大、坂 智文、都築 歩乃佳、吉野 雄太、岡田 卓哉、豊岡 尚樹、遠藤 智史、五
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-20K05751
  • [Presentation] 膵がんの抗がん剤耐性克服を目指した新規オートファジー阻害剤の開発2023

    • Author(s)
      工藤優大,廣田光太郎,都築歩乃佳,吉野雄太,小林奈央, 岡田卓哉, 豊岡尚樹,遠藤智史,五十里彰
    • Organizer
      第40回メディシナルケミストリーシンポジウム
    • Data Source
      KAKENHI-PROJECT-23K06024
  • [Presentation] インシリコ技術を活用した新規機能性分子の開発2023

    • Author(s)
      遠藤 智史
    • Organizer
      第3回 岐阜創薬・医療機器開発フォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K05751
  • [Presentation] 前立腺がん治療の改善を目指した新規オートファジー特異的阻害剤の創製2023

    • Author(s)
      小林奈央, 工藤優大, 藤田芽衣, 吉野雄太, 松永俊之, 五十里彰, 遠藤智史, 岡田卓哉, 豊岡尚樹
    • Organizer
      第40回メディシナルケミストリーシンポジウム
    • Data Source
      KAKENHI-PROJECT-23K06024
  • [Presentation] オートファゴソーム膜の形成を作用点とする新規オートファジー阻害剤の開発2022

    • Author(s)
      工藤 優大、藤田 芽衣、吉野 雄太、鎌足 雄司、田中 義正、石川 岳志、藤本 直浩、岡田 卓哉、豊岡 尚樹、遠藤 智史、
    • Organizer
      第95回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-20K05751
  • [Presentation] 論理的創薬による新規オートファジー阻害剤の創製2022

    • Author(s)
      遠藤 智史
    • Organizer
      日本病院薬剤師会東海ブロック・日本薬学会東海支部 合同学術大会2
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K05751
  • [Presentation] がんアジュバント薬の開発を指向したオートファジー阻害剤の創製研究2022

    • Author(s)
      工藤 優大、藤田 芽衣、吉野 雄太、鎌足 雄司、田中 義正、石川 岳志、藤本 直浩、岡田 卓哉、豊岡 尚樹、遠藤 智史
    • Organizer
      第21回次世代を担う若手のためのファーマ・バイオフォーラム2022
    • Data Source
      KAKENHI-PROJECT-20K05751
  • [Presentation] インシリコ技術を活用した新規機能性分子の開発2022

    • Author(s)
      遠藤 智史
    • Organizer
      第3回 岐阜創薬・医療機器開発フォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K05751
  • [Presentation] オートファゴソーム膜の形成を作用点とする新規オートファジー阻害剤の開発2022

    • Author(s)
      工藤 優大、藤田 芽衣、吉野 雄太、鎌足 雄司、田中 義正、石川 岳志、藤本 直浩、岡田 卓哉、豊岡 尚樹、遠藤 智史、五十里 彰
    • Organizer
      第95回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-20K05751
  • [Presentation] 論理的創薬による新規オートファジー阻害剤の創製2022

    • Author(s)
      遠藤 智史
    • Organizer
      日本病院薬剤師会東海ブロック・日本薬学会東海支部 合同学術大会2022
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K05751
  • [Presentation] 必須脂肪酸によるAtg4B阻害を介した抗がん剤感受性増強効果2022

    • Author(s)
      中村 香菜、工藤 優大、吉野 雄太、中村 光浩、藤本 直浩、高谷 大輔、本間 光貴、遠藤 智史、五十里 彰
    • Organizer
      第95回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-20K05751
  • [Presentation] オートファゴソーム膜形成を標的とした新規オートファジー阻害剤の開発2021

    • Author(s)
      遠藤 智史
    • Organizer
      岐阜大学大学院連合創薬医療情報研究科 2021公開講座
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K05751
  • [Presentation] 前立腺癌治療薬としての新規オートファジー阻害剤の有効性の検証2021

    • Author(s)
      工藤 優大、藤田 芽衣、鎌足 雄司、田中 義正、藤本 直浩、岡田 卓哉、豊岡 尚樹、五十里 彰、遠藤 智史
    • Organizer
      第85回日本生化学会中部支部例会
    • Data Source
      KAKENHI-PROJECT-20K05751
  • [Presentation] オートファジー阻害剤としての新規Atg4B阻害剤の創製2021

    • Author(s)
      工藤 優大、藤田 芽衣、鎌足 雄司、田中 義正、藤本 直浩、岡田 卓哉、豊岡 尚樹、五十里 彰、遠藤 智史
    • Organizer
      第67回日本薬学会東海支部 総会・大会
    • Data Source
      KAKENHI-PROJECT-20K05751
  • [Presentation] 11-ケト-C19-ステロイドの還元代謝酵素の同定2020

    • Author(s)
      工藤 優大、松永 俊之、遠藤 智史
    • Organizer
      日本薬学会第140年会
    • Data Source
      KAKENHI-PROJECT-17K11151
  • [Presentation] Nrf2シグナルを標的としたカバジタキセル耐性前立腺癌に対する治療戦略の開発2020

    • Author(s)
      河合 弥菜、星 真奈美、瀬川 仁、藤田 芽衣、松川 卓生、藤本 直浩、松永 俊之、五十里 彰、遠藤 智史
    • Organizer
      第29回泌尿器科分子・細胞研究会
    • Data Source
      KAKENHI-PROJECT-17K11151
  • [Presentation] 新規オートファジー特異的阻害剤の創製と前立腺癌治療への応用2020

    • Author(s)
      藤田 芽衣、工藤 優大、鎌足 雄司、田中 義正、藤本 直浩、岡田 卓哉、豊岡 尚樹、五十里 彰、遠藤 智史
    • Organizer
      第84回日本生化学会中部支部例会
    • Data Source
      KAKENHI-PROJECT-20K05751
  • [Presentation] 去勢抵抗性前立腺がんの新規治療薬アパルタミドの治療効果の最大化を目指した併用薬の開発2020

    • Author(s)
      瀬川 仁、星 真奈美、河合 弥菜、藤田 芽衣、豊岡 尚樹、藤本 直浩、松永 俊之、五十里 彰、遠藤 智史
    • Organizer
      日本薬学会第140年会
    • Data Source
      KAKENHI-PROJECT-17K11151
  • [Presentation] アンドロゲン合成酵素を標的とした新規去勢抵抗性前立腺がん治療薬の開発2019

    • Author(s)
      遠藤 智史、瀬川 仁、小栗 弘成、夏 爽、胡 大イ、入江 克雅、藤井 晋也、合田 浩明、松川 卓生、藤本 直浩、中山 敏幸、豊岡 尚樹、松永 俊之、五十里 彰
    • Organizer
      第47回構造活性相関シンポジウム
    • Data Source
      KAKENHI-PROJECT-17K11151
  • [Presentation] アルドケト還元酵素1C3を標的とした去勢抵抗性前立腺癌治療薬の創製研究2019

    • Author(s)
      遠藤 智史、河合 弥菜、瀬川 仁、小栗 弘成、藤本 直浩、豊岡 尚樹、松永 俊之、五十里 彰
    • Organizer
      第28回泌尿器科分子・細胞研究会
    • Data Source
      KAKENHI-PROJECT-17K11151
  • [Presentation] 新規3(17)β-ヒドロキシステロイド脱水素酵素DHRS11の性状解析とウサギアイソザイムとの相違点2019

    • Author(s)
      遠藤 智史、宮城 菜未希、松永 俊之、五十里 彰
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17K11151
  • [Presentation] Development and characterization of novel AKR1C3 inhibitors; therapeutic potential for castration-resistant prostate cancer2019

    • Author(s)
      Naohiro Fujimoto, Ikko Tomisaki, Satoshi Endo, Hiroaki Oguri, Naoki Toyooka, Toshiyuki Matsunaga, Akira Ikari and Toshiyuki Nakayama
    • Organizer
      20th International EAUN Meeting EAU19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11151
  • [Presentation] 前立腺癌細胞のカバジタキセル耐性克服に向けたNrf2シグナル制御の意義2019

    • Author(s)
      河合 弥菜、遠藤 智史、星 真奈美、瀬川 仁、藤田 芽衣、松川 卓生、藤本 直浩、松永 俊之、五十里 彰
    • Organizer
      第83回日本生化学会中部支部例会
    • Data Source
      KAKENHI-PROJECT-17K11151
  • [Presentation] Rabbit DHRS11: Identity with acetohexaminde reductase, different from human DHRS112018

    • Author(s)
      Satoshi Endo, Namiki Miyagi, Toshiyuki Matsunaga, Akira Ikari
    • Organizer
      19th International Workshop on the Enzymology and Molecular Biology of Carbonyl Metabolism
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11151
  • [Presentation] マルチターゲット型去勢抵抗性前立腺癌治療薬の創製研究2018

    • Author(s)
      遠藤 智史
    • Organizer
      サラマンカ大学・岐阜薬科大学・岐阜大学 三大学連携学術シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K11151
  • [Presentation] 前立腺癌治療薬の開発を指向したアンドロゲン合成酵素阻害剤の創製研究2018

    • Author(s)
      遠藤 智史、小栗 弘成、藤本 直浩、豊岡 尚樹、松永 俊之、五十里 彰
    • Organizer
      日病薬東海ブロック・薬学会東海支部合同学術大会2018
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K11151
  • [Presentation] マルチターゲット型去勢抵抗性前立腺癌治療薬の創製研究2018

    • Author(s)
      遠藤 智史
    • Organizer
      サラマンカ大学・岐阜薬科大学・岐阜大学 三大学連携学術シンポジウム がん研究の最前線  ~がん克服に向けて(対がん)~
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K11151
  • [Presentation] 抗がん剤によるTRPM6マグネシウムチャネルの発現低下に対するロシグリタゾンの回復効果2018

    • Author(s)
      眞鍋 綾、古川 千紗、遠藤 智史、松永 俊之、長谷川 元、五十里 彰
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Presentation] 去勢抵抗性前立腺癌治療薬を指向した新規AKR1C3阻害剤の創製2018

    • Author(s)
      遠藤 智史
    • Organizer
      第3回名大医薬系3部局交流シンポジウム
    • Data Source
      KAKENHI-PROJECT-17K11151
  • [Presentation] TNF-alphaによるTRPM6マグネシウムチャネルの発現増加機構の解明2017

    • Author(s)
      古川千紗、眞鍋綾、藤井尚子、遠藤智史、松永俊之、山崎泰広、山口賢彦、五十里彰
    • Organizer
      第94回日本生理学会大会
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Presentation] PDZRN3によるクローディン-16マグネシウムチャネルのエンドサイトーシス機構の解明2017

    • Author(s)
      丸中 歌菜、古田 巧、長谷川 元、松永 俊之、遠藤 智史、五十里 彰
    • Organizer
      日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2017
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Presentation] 耐性克服効果を併せ持つ新規抗がん剤開発を指向した選択的AKR1B10阻害剤の創製2017

    • Author(s)
      *遠藤 智史
    • Organizer
      第6回 岐阜構造生物学・医学・論理的創薬研究会シンポジウム
    • Place of Presentation
      岐阜
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460149
  • [Presentation] 分子動力学計算を用いたアルドケト還元酵素AKR1C3のC154Y及びL159V変異体の溶液構造解析2017

    • Author(s)
      渡邉 友里江、早川 大地、遠藤 智史、合田 浩明
    • Organizer
      日本薬学会第138年会 (金沢)
    • Data Source
      KAKENHI-PROJECT-17K11151
  • [Presentation] E3-ユビキチンリガーゼによるクローディン-16マグネシウムチャネルの細胞内局在の調節2017

    • Author(s)
      丸中 歌菜、古川 千紗、藤井 尚子、木村 徹、遠藤 智史、松永 俊之、山口 賢彦、山崎 泰広、五十里 彰
    • Organizer
      第81回日本生化学会中部支部例会
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Presentation] クローディン-2の異常発現による抗がん剤感受性の変化2017

    • Author(s)
      五十里 彰、丸橋 亮平、秋月 梨佐、遠藤 智史、松永 俊之、山崎 泰広、山口 賢彦
    • Organizer
      2017年度生命科学系学会合同年次大会ConBio2017
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Presentation] プリマキンによるクローディン-16変異体の局在異常の改善2017

    • Author(s)
      丸中 歌菜、古田 巧、遠藤 智史、松永 俊之、五十里 彰
    • Organizer
      2017年度生命科学系学会合同年次大会ConBio2017
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Presentation] PDZRN3によるクローディン-16の細胞内局在の調節2017

    • Author(s)
      丸中歌奈、古川千紗、藤井尚子、木村徹、遠藤智史、松永俊之、山崎泰広、山口賢彦、五十里彰
    • Organizer
      第94回日本生理学会大会
    • Place of Presentation
      静岡
    • Year and Date
      2017-03-28
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Presentation] 肺腺がん細胞のクローディン-2発現を抑制するフラボノイドの探索と機序の解明2016

    • Author(s)
      園木寛之、谷前朝海、遠藤智史、松永俊之、五十里彰
    • Organizer
      第38回生体膜と薬物の相互作用シンポジウム
    • Place of Presentation
      愛知
    • Year and Date
      2016-11-17
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Presentation] クラスリン依存性エンドサイトーシスを介した細胞間接着分子claudinの発現調節2016

    • Author(s)
      藤井尚子、遠藤智史、松永俊之、五十里彰
    • Organizer
      日本病院薬剤師会東海ブロック日本薬学会東海支部合同学術大会2016
    • Place of Presentation
      岐阜
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Presentation] 抗がん剤によるMg2+チャネルの発現低下に対するTNF-aの回復効果2016

    • Author(s)
      古川千紗、藤井尚子、遠藤智史、松永俊之、長谷川元、山口賢彦、山崎泰広、菅谷純子、伊藤善規、五十里彰
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      神奈川
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Presentation] 家族性筋萎縮性側索硬化症患者から見出されたアルドケト還元酵素1C3の新規遺伝子変異の性状解析2016

    • Author(s)
      遠藤 智史、高田 明香、本田 諒、Kathrin Muller、鎌足 雄司、松永 俊之、桑田 一夫、Jochen Weishaupt、五十里 彰
    • Organizer
      第62回 日本薬学会東海支部大会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-26460149
  • [Presentation] クローディン-18による肺腺がん細胞の増殖抑制におけるZO-2の関与2016

    • Author(s)
      秋月梨佐、下馬場駿、松永俊之、遠藤智史、五十里彰
    • Organizer
      第63回中部日本生理学会
    • Place of Presentation
      愛知
    • Year and Date
      2016-11-04
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Presentation] Instability of C154Y variant of aldo-keto reductase 1C3 found in familial amyotrophic lateral sclerosis2016

    • Author(s)
      Satoshi Endo, Sayaka Takada, Ryo Honda, Kathrin Muller, Yuji O. Kamatari, Toshiyuki Matsunaga, Kazuo Kuwata, Jochen Weishaupt, Akira Ikari
    • Organizer
      18th International Workshop on the Enzymology and Molecular Biology of Carbonyl Metabolism
    • Place of Presentation
      Costa Brava, Spain
    • Year and Date
      2016-07-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460149
  • [Presentation] 肺腺癌細胞におけるクローディン-2発現に対するHDAC阻害剤の効果2016

    • Author(s)
      岡本美樹、多賀小枝子、七野亜沙美、松永俊之、遠藤智史、五十里彰
    • Organizer
      第80回日本生化学会中部支部シンポジウム
    • Place of Presentation
      三重
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Presentation] 肺腺癌細胞のクローディン-2発現と抗癌剤感受性に対するカフェ酸フェネチルエステルの効果2016

    • Author(s)
      谷前朝海、園木寛之、遠藤智史、松永俊之、五十里彰
    • Organizer
      第7回機能性健康食品研究講演会
    • Place of Presentation
      岐阜
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Presentation] 細胞間接着分子クローディンが起点となる肺扁平上皮癌の細胞増殖調節機構2016

    • Author(s)
      秋月梨佐、下馬場駿、松永俊之、遠藤智史、五十里彰
    • Organizer
      第62回日本薬学会東海支部大会
    • Place of Presentation
      愛知
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Presentation] アンドロゲン合成酵素を標的とした去勢抵抗性前立腺癌治療薬の創製研究2015

    • Author(s)
      遠藤 智史
    • Organizer
      第4回 岐阜構造生物学・医学・論理的創薬研究会シンポジウム (岐阜) 招待講演
    • Place of Presentation
      岐阜
    • Year and Date
      2015-03-05
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460149
  • [Presentation] Aldo-keto reductases as targets for drug development2015

    • Author(s)
      遠藤智史
    • Organizer
      第30回日本薬物動態学会年会
    • Place of Presentation
      東京
    • Year and Date
      2015-11-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460149
  • [Presentation] 肺腺癌細胞におけるクローディン-2のエンドサイトーシスによるネクローシスの誘導2015

    • Author(s)
      五十里彰、多賀小枝子、下馬場俊、遠藤智史、松永俊之、渡邊諒、菅谷純子
    • Organizer
      第88回日本生化学会大会
    • Place of Presentation
      兵庫
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Presentation] クローディン-2指向性ペプチドによるクラスリン依存性エンドサイトーシスを介した細胞障害機構の解明2015

    • Author(s)
      多賀小枝子、下馬場俊、遠藤智史、松永俊之、渡邊諒、佐藤友成、菅谷純子、五十里彰
    • Organizer
      第78回日本生化学会中部支部例会
    • Place of Presentation
      長野
    • Year and Date
      2015-05-23
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Presentation] 高浸透圧によるクローディン-2発現の低下におけるPKCβの関与2015

    • Author(s)
      藤井尚子、遠藤智史、松永俊之、山崎泰広、山口賢彦、菅谷純子、五十里彰
    • Organizer
      第78回日本生化学会中部支部例会
    • Place of Presentation
      長野
    • Year and Date
      2015-05-23
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Presentation] PI3K/Akt経路の阻害を介したクローディン-18による肺腺癌細胞の増殖・浸潤抑制2015

    • Author(s)
      下馬場俊、多賀小枝子、遠藤智史、松永俊之、渡邊諒、佐藤友成、菅谷純子、五十里彰
    • Organizer
      第61回日本薬学会東海支部大会
    • Place of Presentation
      愛知
    • Year and Date
      2015-07-04
    • Data Source
      KAKENHI-PROJECT-15H04657
  • [Presentation] AKR1B10 を標的とする抗癌剤開発を指向した構造活性相関研究2014

    • Author(s)
      陶山 美穂、遠藤 智史、松永 俊之、五十里 彰、胡 大イ、豊岡 尚樹
    • Organizer
      78回日本生化学会中部支部例会
    • Place of Presentation
      名古屋
    • Year and Date
      2014-05-24
    • Data Source
      KAKENHI-PROJECT-26460149
  • [Presentation] ウサギの3-hydroxyhexobarbital dehydrogenaseはketosteroids、prostaglandin D2、その他のカルボニル化合物に広い特異性を示す還元酵素である2013

    • Author(s)
      原明、遠藤智史、山野茂、松本淳子、荒井裕貴、松永俊之
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      横浜
    • Year and Date
      2013-09-13
    • Data Source
      KAKENHI-PROJECT-24790114
  • [Presentation] 2-Phenyliminochromene誘導体の癌マーカーAKR1B10阻害活性に関する構造活性相関2013

    • Author(s)
      陶山 美穂、遠藤 智史、松永 俊之、胡 大イ、杉本 健士、松谷 裕二、豊岡 尚樹、桑田 一夫、原 明
    • Organizer
      第41回構造活性相関シンポジウム
    • Place of Presentation
      西宮
    • Data Source
      KAKENHI-PROJECT-24790114
  • [Presentation] 2-Phenyliminochromene誘導体の癌マーカーAKR1B10阻害活性に関する構造活性相関2013

    • Author(s)
      陶山美穂、遠藤智史、松永俊之、胡大イ、杉本健士、松谷裕二、豊岡尚樹、桑田一夫、原明
    • Organizer
      第41回構造活性相関シンポジウム
    • Place of Presentation
      兵庫
    • Year and Date
      2013-11-07
    • Data Source
      KAKENHI-PROJECT-24790114
  • [Presentation] Modulation of activity and inhibitor sensitivity of rabbit aldose reductase-like protein by oxidized glutathione and SH-reagents2012

    • Author(s)
      Satoshi Endo, Sho Kumada, Airi Fujimoto, Toshiyuki Matsunaga, Satoshi Ohno, Jun'ichi Mano, Kazuo Tajima, Ossama El-Kabbani, and Akira Hara
    • Organizer
      ENZYMOLOGY AND MOLECULAR BIOLOGY OF CARBONYL METABOLISM SIXTEENTH INTERNATIONAL MEETING
    • Place of Presentation
      Plon, GERMANY
    • Data Source
      KAKENHI-PROJECT-24790114
  • [Presentation] Ossama El-Kabbani, and Akira Hara、Modulation of activity and inhibitor sensitivity of rabbit aldose reductase-like protein by oxidized glutathione and SH-reagents2012

    • Author(s)
      Satoshi Endo, Sho Kumada, Airi Fujimoto, Toshiyuki Matsunaga, Satoshi Ohno, Jun'ichi Mano, Kazuo Tajima
    • Organizer
      ENZYMOLOGY AND MOLECULAR BIOLOGY OF CARBONYL METABOLISM SIXTEENTH INTERNATIONAL MEETING
    • Place of Presentation
      Plön, GERMANY
    • Data Source
      KAKENHI-PROJECT-24790114
  • [Presentation] 高次構造に基づいた癌マーカーAKR1B10の強力かつ選択的な阻害剤の創製2012

    • Author(s)
      遠藤智史
    • Organizer
      第1回岐阜構造生物学・医学・論理的創薬研究会シンポジウム
    • Place of Presentation
      岐阜
    • Year and Date
      2012-02-23
    • Data Source
      KAKENHI-PROJECT-21790245
  • [Presentation] Design, Synthesis and Evaluation of Caffeic Acid Phenethyl Ester-Based Inhibitors Targeting a Selectivity Pocket in the Active Site of Human Aldo-Keto Reductase (AKE) 1B102011

    • Author(s)
      Satoshi Endo, 他11名
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-30
    • Data Source
      KAKENHI-PROJECT-21790245
  • [Presentation] Design, Synthesis and Evaluation of Caffeic Acid Phenethyl Ester-Based Inhibitors Targeting a Selectivity Pocket in the Active Site of Human Aldo-Keto Reductase(AKR) 1B102011

    • Author(s)
      Satoshi Endo, Toshiyuki Matsunaga, Midori Soda, Mayuko Takemura, Dawei Hu, Jie Li, Ryogo Wada, Syohei Ifuku, Naoki Toyooka, Hai-Tao Zhao, Ossama El-Kabbani and Akira
    • Organizer
      8th AFMC International Medicinal Chemistry Symposium(AIMECS11)
    • Place of Presentation
      東京
    • Year and Date
      2011-11-30
    • Data Source
      KAKENHI-PROJECT-21790245
  • [Presentation] Roles of rat and human aldo-keto reductases in metabolism of farnesol and geranylgeraniol2010

    • Author(s)
      Satoshi Endo, Toshiyuki Matsunaga, Chisato Ohta, Midori Soda, Ayano Kanamori, Yukio Kitade, Satoshi Ohno, Kazuo Tajima, Ossama El-Kabbani, Akira Hara
    • Organizer
      ENZYMOLOGY AND MOLECULAR BIOLOGY OF CARBONYL METABOLISM FIFTEENTH INTERNATIONAL MEETING
    • Place of Presentation
      LEXINGTON, KENTUCKY
    • Data Source
      KAKENHI-PROJECT-21790245
  • [Presentation] バーチャルスクリーニングを用いた癌マーカー酵素AKR1B10の強力な阻害剤の探索2010

    • Author(s)
      遠藤智史、松永俊之、桑田一夫、Ossama El-Kabbani、北出幸夫、原明
    • Organizer
      74回日本生化学会中部支部例会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-05-29
    • Data Source
      KAKENHI-PROJECT-21790245
  • [Presentation] 非ステロイド性抗炎症薬による癌マーカーAKR1B10の阻害2010

    • Author(s)
      遠藤智史、松永俊之、曽田翠、田島和男、Ossama El-Kabbani, 原明
    • Organizer
      第56回日本薬学会東海支部総会・大会
    • Place of Presentation
      岐阜
    • Year and Date
      2010-07-03
    • Data Source
      KAKENHI-PROJECT-21790245
  • [Presentation] Roles of rat and human aldo-keto reductases in metabolism of farnesol and geranylgeraniol.2010

    • Author(s)
      Satoshi Endo
    • Organizer
      ENZYMOLOGY AND MOLECULAR BIOLOGY OF CARBONYL METABOLISM FIFTEENTH INTERNATIONAL MEETING
    • Place of Presentation
      LEXINGTON, KENTUCKY, USA
    • Data Source
      KAKENHI-PROJECT-21790245
  • [Presentation] アルドケト還元酵素AKR1C3の脂肪族アルデヒドに対する特異性と選択的阻害剤2010

    • Author(s)
      金森綾野、遠藤智史、松永俊之、原明, Ossama El-Kabbani
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-21790245
  • [Presentation] 癌マーカーAKR1B10によるイソプレニルアルデヒド還元代謝2009

    • Author(s)
      遠藤智史
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      兵庫
    • Year and Date
      2009-10-22
    • Data Source
      KAKENHI-PROJECT-21790245
  • [Presentation] Inhibitory Effects of Drugs and Dietary Plant Components on the Tumor Marker AKR1B102009

    • Author(s)
      Satoshi Endo
    • Organizer
      日本薬物動態学会第24回年会
    • Place of Presentation
      京都
    • Year and Date
      2009-11-28
    • Data Source
      KAKENHI-PROJECT-21790245
  • [Presentation] ヒトの新規カルボニル還元酵素遺伝子産物(CBR4)の機能解析2009

    • Author(s)
      遠藤智史
    • Organizer
      第53回日本薬学会東海支部総会・大会
    • Place of Presentation
      愛知
    • Year and Date
      2009-07-11
    • Data Source
      KAKENHI-PROJECT-21790245
  • [Presentation] 高次構造に基づく20α-ヒドロキシステロイド脱水素酵素阻害剤の合成・評価2009

    • Author(s)
      曽田翠、遠藤智史、松永俊之、原明、Ossama El-Kabbani
    • Organizer
      73回日本生化学会中部支部例会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-05-23
    • Data Source
      KAKENHI-PROJECT-21790245
  • [Presentation] 癌マーカーAKR1B10によるイソプレニルアルデヒド還元代謝2009

    • Author(s)
      遠藤智史、松永俊之、曽田翠、原明、田島和男
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-22
    • Data Source
      KAKENHI-PROJECT-21790245
  • [Presentation] Characterization of a rat aldo-keto reductase (AKR1B13) up-regulated by oxidative stress2008

    • Author(s)
      Satoshi Endo
    • Organizer
      ENZYMOLOGY AND MOLECULAR BIOLOGY OF CARBONYL METABOLISM 14th INTERNATIONAL MEETING
    • Place of Presentation
      KRANTSKA GORA, SLOVENIA
    • Data Source
      KAKENHI-PROJECT-19890180
  • [Presentation] Characterization of a rat aldo-keto reductase (AKR1B13) up-regulated by oxidative stress2008

    • Author(s)
      Satoshi Endo, Toshiyuki Matsunaga, Hiroaki Mamiya, Akira Hara, Kazuo Tajima, Yukio Kitade, Ossama El-Kabbani
    • Organizer
      ENZYMOLOGY AND MOLECULAR BIOLOGY OF CARBONYL METABOLISM FOURTEENTH INTERNATIONAL MEETING
    • Place of Presentation
      KRANJSKA GORA, SLOVENIA JULY
    • Year and Date
      2008-07-11
    • Data Source
      KAKENHI-PROJECT-19890180
  • [Presentation] ヒトの誘導性SDR ファミリータンパク質(DHRS4)の性状2008

    • Author(s)
      前田 哲志、遠藤 智史、松永 俊之、原明、田中 信忠、中村 和郎、田島 和男
    • Organizer
      第72 回日本生化学会中部支部例会
    • Place of Presentation
      岐阜
    • Year and Date
      2008-05-24
    • Data Source
      KAKENHI-PROJECT-19890180
  • [Presentation] Identification of substrate specificity determinants of rodent NAD+-dependent 3α/17β/20α-hydroxysteroid dehydrogenases by site-directed mutagenesis2007

    • Author(s)
      遠藤智史
    • Organizer
      第80回 日本生化学会大会 第30回 日本分子生物学会年会 合同大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-19890180
  • [Presentation] Identification of substrate specificity determinants of rodent NAD+-dependent 3a/17b/20a-hydroxysteroid dehydrogenases by site-directed mutagenesis2007

    • Author(s)
      Satoshi Endo, Toshiyuki Matsunaga, Kazuo Tajima, and Akira Hara
    • Organizer
      第80 回 日本生化学会大会 第30 回 日本分子生物学会年会 合同大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-19890180
  • [Presentation] ヒトの新規カルボニル還元酵素遺伝子産物(CBR4)の機能解析

    • Author(s)
      遠藤智史, 松永俊之, 北出幸夫, 田島和男, Ossama El-Kabbani, 原明
    • Data Source
      KAKENHI-PROJECT-21790245
  • [Presentation] Aldo-keto reductase1C3(AKR1C3) 選択的阻害活性を有する baccharin非プレニル誘導体の合成

    • Author(s)
      遠藤 智史、胡 大イ、松永 俊之、大辻 陽子、Ossama EI-Kabbani、Mahmoud Kandeel、五十里 彰、原 明、北出 幸夫、豊岡 尚樹
    • Organizer
      第32回メディシナルシンポジウム(神戸)
    • Place of Presentation
      神戸
    • Year and Date
      2014-11-26 – 2014-11-28
    • Data Source
      KAKENHI-PROJECT-26460149
  • 1.  TOYOOKA Naoki (10217565)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 2.  HARA Akira (00094334)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 3.  GODA Hiroaki (60276160)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 4.  TANAKA Nobutada (00286866)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  KUWATA Kazuo (00170142)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 6.  IKARI AKIRA (50315850)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 29 results
  • 7.  古田 巧 (30336656)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 8.  KATO Atsushi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MATSUNAGA Toshiyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 10.  EL-KABBANI Ossama
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 11.  ISHIKAWA Takeshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  HONDA Ryo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  酒井 秀紀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  鎌足 雄司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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