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Nakanishi Masako  中西 雅子

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… Alternative Names

中西 雅子  ナカニシ マサコ

NAKANISHI Masako  中西 雅子

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Researcher Number 60437382
Affiliation (Current) 2025: 和歌山県立医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2022 – 2023: 和歌山県立医科大学, 医学部, 講師
2016 – 2020: 和歌山県立医科大学, 医学部, 講師
2013 – 2015: 和歌山県立医科大学, 医学部, 助教
2011 – 2012: 大阪医科大学, 医学部, 助教
2010: 大阪大学, 大学院・歯学研究科, 特任研究員 … More
2008: Osaka University, 大学院・歯学研究科, 特任研究員
2008: Osaka University, 大学院歯学研究科, 特任研究員
2007: Osaka University, 歯学研究科, 特任研究員 Less
Review Section/Research Field
Principal Investigator
Basic Section 55010:General surgery and pediatric surgery-related / Pathobiological dentistry/Dental radiology / General surgery / Anesthesiology/Resuscitation studies
Keywords
Principal Investigator
酸感受性受容体 / 癌微小環境 / リンパ管内皮細胞 / 動物モデル / 骨転移 / 癌性疼痛 / 酸性微小環境 / リンパ節転移 / アシドーシス / 転移 … More / VCAM-1 / 酸性環境 / 微小環境 / 癌性骨痛 Less
  • Research Projects

    (6 results)
  • Research Products

    (47 results)
  • Co-Researchers

    (3 People)
  •  Acid sensing receptors in functional change of lymphatic endothelial cells and cancer metastasis.Principal Investigator

    • Principal Investigator
      中西 雅子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Wakayama Medical University
  •  Acidic microenvironment promotes lymphatic metastasis via the functional changes of lymphatic endothelial cellsPrincipal Investigator

    • Principal Investigator
      Nakanishi Masako
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Wakayama Medical University
  •  Molecular analysis of lymph node metastasis via the crosstalk with acidic microenvironmentPrincipal Investigator

    • Principal Investigator
      Nakanishi Masako
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Wakayama Medical University
  •  Molecular analysis of bone metastatic painPrincipal Investigator

    • Principal Investigator
      NAKANISHI Masako
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Wakayama Medical University
      Osaka Medical College
  •  The role of acid sensing nociceptors in the development of cancer-induced bone painPrincipal Investigator

    • Principal Investigator
      NAKANISHI Masako
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Osaka Medical College
      Osaka University
  •  The analgesic mechanism of low dose irradiation on the cancer-inducedbone painPrincipal Investigator

    • Principal Investigator
      NAKANISHI Masako
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Osaka University

All 2024 2023 2022 2021 2020 2018 2017 2016 2015 2014 2013 2012 2011 2010 2008 Other

All Journal Article Presentation Book

  • [Book] 癌と骨2013

    • Author(s)
      中西雅子、波多賢二、米田俊之
    • Total Pages
      347
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-24592363
  • [Journal Article] Acid-sensing receptor GPR4 plays a crucial role in lymphatic cancer metastasis2024

    • Author(s)
      Masako Nakanishi, Akiya Ibe, Kiyoto Morishita, Kazutaka Shinagawa, Yushi Yamamoto, Hibiki Takahashi, Kyoka Ikemori, Yasuteru Muragaki, Shogo Ehata
    • Journal Title

      Cancer Science

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08699
  • [Journal Article] Acidic microenvironment induction of interleukin-8 expression and matrix metalloproteinase-2/-9 activation via acid-sensing ion channel 1 promotes breast cancer cell progression2021

    • Author(s)
      Nakanishi M, Korechika A, Yamakawa H, Kawabe N, Nakai K, Muragaki Y.
    • Journal Title

      Oncol Rep.

      Volume: 45 Issue: 3 Pages: 1284-1294

    • DOI

      10.3892/or.2020.7907

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08659, KAKENHI-PROJECT-18K08580
  • [Journal Article] The Gain-of-Function Mutation p53R248W Suppresses Cell Proliferation and Invasion of Oral Squamous Cell Carcinoma through the Down-Regulation of Keratin 172021

    • Author(s)
      Enaka M, Nakanishi M, Muragaki Y.
    • Journal Title

      American Journal of Pathology

      Volume: 191 Issue: 3 Pages: 555-566

    • DOI

      10.1016/j.ajpath.2020.11.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08659, KAKENHI-PROJECT-18K08580
  • [Journal Article] Acidic micro environments induce lymphangiogenesis and IL-8 production via TRPV1 activation in human lymphatic endothelial cells2016

    • Author(s)
      Nakanishi M, Morita Y, Hata K, Muragaki Y
    • Journal Title

      Experimental Cell Research

      Volume: 345 Pages: 180-189

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K10064
  • [Journal Article] Cellular fibronectin 1 promotes VEGF-C expression, lymphangiogenesis and lymph node metastasis associated with human oral squamous cell carcinoma2015

    • Author(s)
      Yoshihiro Morita, Kenji Hata, Masako Nakanishi, Tetsuji Omata, Nobuo Morita, Yoshiaki Yura, Riko Nishimura, Toshiyuki Yoneda
    • Journal Title

      Clinical and Experimental Metastasis

      Volume: 32 Issue: 7 Pages: 739-753

    • DOI

      10.1007/s10585-015-9741-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K10064, KAKENHI-PROJECT-24390453
  • [Journal Article] Cyclooxygenase-2 expression is associated with vascular endothelial growth factor-c and lymph node metastasis in human oral tongue cancer2014

    • Author(s)
      Morita Y, Morita N, Hata K, Nakanishi M, Kimoto N, Omata T, Nakamura Y, Yoneda T
    • Journal Title

      Oral Surg Oral Med Oral Pathol Oral Radiol

      Volume: 117(4) Issue: 4 Pages: 502-510

    • DOI

      10.1016/j.oooo.2013.12.410

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390422, KAKENHI-PROJECT-24592363, KAKENHI-PROJECT-26293394, KAKENHI-PROJECT-26670806
  • [Journal Article] 骨転移に伴う疼痛のメカニズム2014

    • Author(s)
      中西雅子
    • Journal Title

      腎と骨代謝

      Volume: 27 Pages: 41-46

    • Data Source
      KAKENHI-PROJECT-24592363
  • [Journal Article] Arid5b facilitates chondrogenesis by recruiting the histone demethylase Phf2 to Sox9-regulated genes2013

    • Author(s)
      Hata K, Takashima R, Amano K, Ono K, Nakanishi M, Yoshida M, Wakabayashi M, Matsuda A, Maeda Y, Suzuki Y, Sugano S, Whitson RH, Nishimura R and Yoneda T
    • Journal Title

      Nature communications

      Volume: 4 Issue: 1 Pages: 2850-2860

    • DOI

      10.1038/ncomms3850

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592363, KAKENHI-PROJECT-24659824, KAKENHI-PROJECT-25293378, KAKENHI-PROJECT-25293401
  • [Journal Article] Involvement of acidic microenvironment in the pathophysiology of cancer-associated bone pain2011

    • Author(s)
      Yoneda T, Hata K, Nakanishi M, Nagae M, Nagayama T, Wakabayashi H, Nishisho T, Sakurai T and Hiraga T
    • Journal Title

      Bone

      Volume: 48 Pages: 100-105

    • Data Source
      KAKENHI-PROJECT-22791811
  • [Journal Article] The a3 isoform vacuolar type H+-ATPase promotes distant metastasis in the mouse B16 melanoma cells2011

    • Author(s)
      Nishisho T, Hata K, Nakanishi M, Morita Y, Sun-Wada H, Wada Y, Yasui N, Yoneda T
    • Journal Title

      Mol Cancer Res

      Volume: 9 Pages: 845-855

    • Data Source
      KAKENHI-PROJECT-22791811
  • [Journal Article] Encounter of cancer cells with bone. The bone microenvironment and cancer metastasis2011

    • Author(s)
      Hata K, Nakanishi M, Morita Y, Yoneda T
    • Journal Title

      Clin Calcium

      Volume: 21 Pages: 329-355

    • Data Source
      KAKENHI-PROJECT-22791811
  • [Journal Article] Encounter of cancer cells with bone. Molecular mechanism of cancer-induced bone pain2011

    • Author(s)
      Nakanishi M, Hata K, Yoneda T
    • Journal Title

      Clin Calcium

      Volume: 21 Pages: 357-362

    • Data Source
      KAKENHI-PROJECT-22791811
  • [Journal Article] 骨転移に伴うがん性骨痛の分子メカニズム2011

    • Author(s)
      中西雅子、波多賢二、米田俊之
    • Journal Title

      CLINICAL CALCIUM

      Volume: 21 Pages: 357-363

    • Data Source
      KAKENHI-PROJECT-22791811
  • [Journal Article] Acid activation of Trpv1 leads to an up-regulation of calcitonin gene related peptide expression in dorsal root ganglion neurons via the CaMK-CREB cascade : A potential mechanism of inflammatory pain2010

    • Author(s)
      Nakanishi M, Hata K, Nagayama T, Sakurai T, Nishisho T, Wakabayashi H, Hiraga T, Ebisu S and Yoneda T
    • Journal Title

      Mol. Biol. Cell

      Volume: 21 Pages: 2568-2577

    • Data Source
      KAKENHI-PROJECT-22791811
  • [Journal Article] Acid activation of Trpv1 leads to an up-regulation of CGRP expression in DRG neurons via the CaMK-CREB cascade : a potential mechanism of inflammatory pain.2010

    • Author(s)
      Masako Nakanishi
    • Journal Title

      Mol Biol Cell

      Volume: 21 Pages: 2568-2577

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791811
  • [Presentation] Acidic cancer microenvironment promotes lymphatic metastasis via the activation of an acid-sensing receptor GPR42023

    • Author(s)
      Masako Nakanishi, Akiya Ibe, Kiyoto Morishita, Mizuki Nishikawa, Yasuteru Muragaki, Shogo Ehata
    • Organizer
      第82回日本癌学会
    • Data Source
      KAKENHI-PROJECT-22K08699
  • [Presentation] 癌の酸性微小環境は酸感受性受容体GPR4を介してリンパ行性転移を促進する2023

    • Author(s)
      井邊晶也、中西雅子、森下清登、品川一貴、山元悠史、高橋響、池森恭花、村垣泰光、江幡正悟
    • Organizer
      第51回和歌山悪性腫瘍研究会
    • Data Source
      KAKENHI-PROJECT-22K08699
  • [Presentation] The role of Thy-1 induced in lymphatic endothelial cells in an acidic cancer microenvironment2023

    • Author(s)
      Akiya Ibe, Masako Nakanishi, Hyuga Kajiri, Ryo Matsumoto, Yasuteru Muragaki, Shogo Ehata
    • Organizer
      第112回日本病理学会
    • Data Source
      KAKENHI-PROJECT-22K08699
  • [Presentation] Acid receptor GPR4 plays crucial roles in lymphatic cancer metastasis2023

    • Author(s)
      Masako Nakanishi, Akiya Ibe, Kiyoto Morishita, Kazutaka Shinagawa, Yushi Yamamoto, Hibiki Takahashi, Kyoka Ikemori, Yasuteru Muragaki, Shogo Ehata
    • Organizer
      第112回日本病理学会
    • Data Source
      KAKENHI-PROJECT-22K08699
  • [Presentation] Acidic cancer microenvironment promotes lymphatic metastasis via the induction of Thy-1 in lymphatic endothelial cells2023

    • Author(s)
      Akiya Ibe, Masako Nakanishi, Kurumi Higashimoto, Yasuteru Muragaki, Shogo Ehata
    • Organizer
      第82回日本癌学会
    • Data Source
      KAKENHI-PROJECT-22K08699
  • [Presentation] Acidic cancer microenvironment alters the function of lymphatic endothelial cells via increased chemokine production2022

    • Author(s)
      Masako Nakanishi, Akiya Ibe, Kiyoto Morishita, Mizuki Nishikawa, Shogo Ehata
    • Organizer
      第81回 日本癌学会
    • Data Source
      KAKENHI-PROJECT-22K08699
  • [Presentation] Functional alterations of lymphatic endothelial cells due to increased chemokine production in an acidic tumor microenvironment2022

    • Author(s)
      Akiya Ibe, Kazutaka Shinagawa, Kiyoto Morishita, Masako Nakanishi, Yasuteru Muragaki, Shogo Ehata
    • Organizer
      第111回 日本病理学会
    • Data Source
      KAKENHI-PROJECT-22K08699
  • [Presentation] Acidic microenvironment promotes lymphatic metastasis via the induction of VCAM-1 in lymphatic endothelial cells.2020

    • Author(s)
      Nakanishi M, Muragaki Y
    • Organizer
      第79回日本癌学会
    • Data Source
      KAKENHI-PROJECT-18K08580
  • [Presentation] 癌組織の酸性環境はリンパ管内皮細胞におけるVCAM-1の発現誘導を介してリンパ節転移モデルを転移を促進する2020

    • Author(s)
      中西雅子、池森恭花、村垣泰光
    • Organizer
      第109回日本病理学会
    • Data Source
      KAKENHI-PROJECT-18K08580
  • [Presentation] 癌組織の酸性微小環境はリンパ管内皮細胞におけるVCAM-1の発現誘導を介してリンパ節転移を促進する2020

    • Author(s)
      中西雅子、池森恭花、村垣泰光
    • Organizer
      第109回日本病理学会
    • Data Source
      KAKENHI-PROJECT-18K08580
  • [Presentation] 乳癌骨転移におけるCPEB3の役割2018

    • Author(s)
      中西雅子、新井理紗、服部綾乃、林真里、波多賢二、米田俊之、村垣泰光
    • Organizer
      第107回日本病理学会
    • Data Source
      KAKENHI-PROJECT-18K08580
  • [Presentation] The role of CPEB3 in the development of breast cancer bone metastases2018

    • Author(s)
      Masako Nakanishi, Kenji Hata, Yasuteru Muragaki
    • Organizer
      第77回日本癌学会
    • Data Source
      KAKENHI-PROJECT-18K08580
  • [Presentation] Acidic microenvironment contributes the cancer malignancy via IL-8 production2017

    • Author(s)
      Nakanishi M, Korechika A, Yamakawa H, Kawabe N, Muragaki Y
    • Organizer
      第106回日本病理学会
    • Data Source
      KAKENHI-PROJECT-15K10064
  • [Presentation] 癌の悪性化における酸性微小環境の関与2016

    • Author(s)
      中西雅子、是近彩香、山川はるか、川部直子、村垣泰光
    • Organizer
      第105回日本病理学会
    • Place of Presentation
      仙台
    • Year and Date
      2016-05-13
    • Data Source
      KAKENHI-PROJECT-15K10064
  • [Presentation] Acidic microenvironment contributes the development of cancer malignancy via IL-8 production2016

    • Author(s)
      Masako Nakanishi, Yasuteru Muragaki
    • Organizer
      第75回日本癌学会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K10064
  • [Presentation] Acidic microenvironment accelerates lymph node metastasis via the functional changes of LEC2015

    • Author(s)
      Masako Nakanishi, Yoshihiro Morita, Kenji Hata, Yasuteru Muragaki
    • Organizer
      第104回日本病理学会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-04-30
    • Data Source
      KAKENHI-PROJECT-15K10064
  • [Presentation] Acidic microenvironment is involved in lymph node metastasis through changes of lymphatic endothelial cells2015

    • Author(s)
      Masako Nakanishi, Yoshihiro Morita, Kenji Hata, Yasuteru Muragaki
    • Organizer
      第74回日本癌学会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-15K10064
  • [Presentation] 酸性環境によるTrpv1の活性化はCGRPの発現増加を介して骨転移痛に関与する2013

    • Author(s)
      中西雅子
    • Organizer
      第118回日本解剖学会
    • Place of Presentation
      高松
    • Data Source
      KAKENHI-PROJECT-24592363
  • [Presentation] Involvement of acidic microenvironment on the cancer-induced bone pain2012

    • Author(s)
      Masako Nakanishi, Kenji Hata, Toshiyuki Yoneda
    • Organizer
      第117回日本解剖学会
    • Place of Presentation
      甲府
    • Year and Date
      2012-03-28
    • Data Source
      KAKENHI-PROJECT-22791811
  • [Presentation] Up-regulation of CGRP expression by acid-activated calcium channel nociceptor Trpv1 is involved in bone pain.2011

    • Author(s)
      中西雅子
    • Organizer
      第5回Bone Research Seminar
    • Place of Presentation
      東京コンファレンスセンター(招待講演)
    • Year and Date
      2011-02-19
    • Data Source
      KAKENHI-PROJECT-22791811
  • [Presentation] Up-regulation of CGRP expression by acid-activated calcium channel nociceptor Trpv1 is involved in bone pain2011

    • Author(s)
      中西雅子、波多賢二、永山智崇、西庄俊彦、米田俊之
    • Organizer
      第5回Bone Research Seminar
    • Place of Presentation
      東京
    • Year and Date
      2011-02-19
    • Data Source
      KAKENHI-PROJECT-22791811
  • [Presentation] Up-regulation of CGRP expression by acid-activated calcium channel nociceptor Trpv1 is involved in bone pain.2010

    • Author(s)
      Masako Nakanishi
    • Organizer
      The American Society for Bone and Mineral Research 2010 Annual Meeting
    • Place of Presentation
      Metro Toronto Convention Center(Canada)
    • Year and Date
      2010-10-18
    • Data Source
      KAKENHI-PROJECT-22791811
  • [Presentation] Acid microenvironment in bone metastases is involved in pain signal through CGRP regulation following Trpv1 activation.2010

    • Author(s)
      Masako Nakanishi
    • Organizer
      第69回日本癌学会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-22791811
  • [Presentation] Up-regulation of CGRP expression by acid-activated calcium channel nociceptor Trpv1 is involved in bone pain2010

    • Author(s)
      Masako Nakanishi, Kenji Hata, Tomotaka Nagayama, Toshihiko Nishisho, Toshiyuki Yoneda
    • Organizer
      The American Society for Bone and Mineral Research 2010 Annual Meeting
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2010-10-18
    • Data Source
      KAKENHI-PROJECT-22791811
  • [Presentation] 骨転移巣の酸性環境は知覚神経TRPV1の活性化によるCGRPの発現増加を介して疼痛を誘発する2010

    • Author(s)
      中西雅子、波多賢二、西庄俊彦、米田俊之
    • Organizer
      第28回日本骨代謝学会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-23
    • Data Source
      KAKENHI-PROJECT-22791811
  • [Presentation] 骨転移巣の酸性環境はTRPV1の活性化によるCGRPの発現増加を介して疼痛に関与する2010

    • Author(s)
      中西雅子、米田俊之
    • Organizer
      第69回日本癌学会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-22791811
  • [Presentation] 骨転移巣の酸性環境は知覚神経TRPV1の活性化によるCGRPの発現増加を介して疼痛を誘発する2010

    • Author(s)
      中西雅子
    • Organizer
      第28回日本骨代謝学会
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2010-07-23
    • Data Source
      KAKENHI-PROJECT-22791811
  • [Presentation] 癌性骨痛の発生における酸性環境の関与2008

    • Author(s)
      中西雅子
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-19791379
  • [Presentation] 癌性骨痛の発生における酸性環境の関与2008

    • Author(s)
      中西雅子、米田俊之
    • Organizer
      第67 回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-19791379
  • [Presentation] 骨転移巣の酸性環境はTRPV1の活性化によるCGRPの発現増加を介して疼痛に関与する

    • Author(s)
      中西雅子、波多賢二、米田俊之、村垣泰光
    • Organizer
      第103回日本病理学会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-24592363
  • [Presentation] 骨転移巣の酸性環境はTrpv1の活性化によるCGRPの発現増加を介して疼痛に関与する

    • Author(s)
      中西雅子、波多賢二、米田俊之、村垣泰光
    • Organizer
      第103回日本病理学会
    • Place of Presentation
      広島
    • Year and Date
      2014-04-25 – 2014-04-27
    • Data Source
      KAKENHI-PROJECT-24592363
  • 1.  HATA Kenji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 2.  村垣 泰光
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 3.  米田 俊之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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