Hama Susumu 濱進

… Alternative Names

濱進ハマススム

HAMA Susumu 濱進

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Researcher Number	60438041
Other IDs
Affiliation (Current)	2025: 武蔵野大学, 薬学部, 講師 2025: 京都薬科大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help	2023: 武蔵野大学, 薬学部, 講師 2013 – 2020: 京都薬科大学, 薬学部, 講師 2008 – 2012: Kyoto Pharmaceutical University, 薬学部, 助教 2009: 札幌医科大学, 医学部, 助教 2007: Sapporo Medical University, 医学部, 助教 2006: 札幌医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Physical pharmacy / Basic Section 90120:Biomaterials-related / Medical pharmacy Except Principal Investigator Physical pharmacy / Biological Sciences
Keywords	Principal Investigator がん微小環境 / DDS / 腫瘍微小環境 / ドラッグデリバリー / 癌微小環境 / ドラッグデリバリーシステム / 脂質ナノ粒子 / 血中滞留性素子 / ポレチレングリコール（PEG）ジレンマ / 血中滞留性 … More / 核酸 / 腫瘍内透過 / 薬物放出 / 低pH / ナノDDS / 診断法 / 体液診断 / 遺伝子治療 / 抗体 / 低酸素 / 乳癌 / がん幹細胞 / 幹細胞 … More Except Principal Investigator siRNA / 癌治療 / 癌微小環境 / 癌細胞間隙 / ナノDDS / B細胞系の腫瘍 / 悪性神経膠腫 / アデノウイルスベクター / アテノイルスベクター / 遺伝子冶療 / 前立腺癌 / 悪性黒色腫 / 膵癌 / 標的化遺伝子導入 / 標的化抗体 / モノクローナル抗体 / アデノウィルスベクター / 遺伝子治療 Less

Control of tumor microenvironment by lipid nanoparticles modified with novel blood-circulating moleculesPrincipal Investigator
- Principal Investigator
  
  濱進
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Musashino University
Improvement of the surface properties of nanoparticles by using a novel stealth device and their application to nucleic acid carrier controlling tumor microenvironment.Principal Investigator
- Principal Investigator
  
  Hama Susumu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Kyoto Pharmaceutical University
Development of nucleic acids carriers equipped with tumor microenvironment-sensitive peptides for the therapy of metastatic liver cancer(Fostering Joint International Research)Principal Investigator
- Principal Investigator
  
  Hama Susumu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Development of nucleic acids carriers equipped with tumor microenvironment-sensitive peptides for the therapy of metastatic liver cancerPrincipal Investigator
- Principal Investigator
  
  Hama Susumu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Development of slightly acidic pH-sensitive nanoparticles being capable of size-selective drug release for cancer therapy and diagnosisPrincipal Investigator
- Principal Investigator
  
  HAMA Susumu
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Development of a novel type worm-like DDS penetrable into tumor tissue
- Principal Investigator
  
  KOGURE Kentaro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Development of tumor microenvironment responsive nanoparticles and investigation of the antitumor effectPrincipal Investigator
- Principal Investigator
  
  HAMA Susumu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Development of gene therapy and sensitive diagnostic method using an antibody for hypoxic breast cancerPrincipal Investigator
- Principal Investigator
  
  HAMA Susumu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto Pharmaceutical University
  Sapporo Medical University
Selective targeted drug and gene delivery for cancer treatment
- Principal Investigator
  
  HAMADA Hirohumi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University

[Book] DDS先端技術の製剤への応用開発2017
- Author(s)
  濱進、板倉祥子、小暮健太朗
- Publisher
  技術情報協会
- Data Source
  KAKENHI-PROJECT-15K07907
[Book] Stem Cell Repair and Regeneration2005
- Author(s)
  Hamada H
- Publisher
  Imperial College Press
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] Develop liposome-based drug carriers in response to tumour microenvironment2018
- Author(s)
  Hama S
- Journal Title
  
  Impact
  
  Volume: 12 Issue: 12 Pages: 73-75
- DOI
  10.21820/23987073.2018.12.73
- Open Access
- Data Source
  KAKENHI-PROJECT-15KK0357
[Journal Article] Tumor Microenvironment-Sensitive Liposomes Penetrate Tumor Tissue via Attenuated Interaction of the Extracellular Matrix and Tumor Cells and Accompanying Actin Depolymerization.2017
- Author(s)
  Suzuki S, Itakura S, Matsui R, Nakayama K, Nishi T, Nishimoto A, Hama S, Kogure K.
- Journal Title
  
  Biomacromolecules.
  
  Volume: 18 Issue: 2 Pages: 535-543
- DOI
  10.1021/acs.biomac.6b01688
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K07907
[Journal Article] Effective cytoplasmic release of siRNA from liposomal carriers by controlling the electrostatic interaction of siRNA with a charge-invertible peptide, in response to cytoplasmic pH.2016
- Author(s)
  Shoko Itakura, Susumu Hama, Ryo Matsui, Kentaro Kogure
- Journal Title
  
  Nanoscale
  
  Volume: in press Issue: 20 Pages: 10649-10658
- DOI
  10.1039/c5nr08365f
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-14J09314, KAKENHI-PROJECT-15K07907
[Journal Article] Overcoming the polyethylene glycol dilemma via pathological environment-sensitive change of the surface property of nanoparticles for cellular entry.2015
- Author(s)
  Susumu Hama, Shoko Itakura, Mayumi Nakai, Kayoko Nakayama, Satoshi Morimoto, Satoko Suzuki, Kentaro Kogure.
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 206 Pages: 67-74
- DOI
  10.1016/j.jconrel.2015.03.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J09314, KAKENHI-PROJECT-25860030
[Journal Article] Development of a novel nanoparticle by dual modification with the pluripotential cell-penetrating peptide PepFect6 for cellular uptake, endosomal escape, and decondensation of an siRNA core complex2013
- Author(s)
  Mitsueda A, Shimatani Y, Ito M, Ohgita T, Yamada A, Hama S, Gräslund A, Lindberg S, Langel U, Harashima H, Nakase I, Futaki S, Kogure K
- Journal Title
  
  Biopolymers
  
  Volume: Vol.100 Issue: 6 Pages: 698-704
- DOI
  10.1002/bip.22310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390014, KAKENHI-PROJECT-23790129
[Journal Article] Development of a Novel Drug Delivery System consisting of an Antitumor Agent Tocopheryl Succinate2012
- Author(s)
  Hama S, Utsumi S, Fukuda Y, Nakayama K, Okamura Y, Tsuchiya H, Fukuzawa K, Harashima H, Kogure K
- Journal Title
  
  Journal of Control release
  
  Volume: 161(3) Issue: 3 Pages: 843-851
- DOI
  10.1016/j.jconrel.2012.05.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229001, KAKENHI-PROJECT-23390014
[Journal Article] Protective effects of topical application of a poorly soluble antioxidant astaxanthin liposomal formulation on ultraviolet-induced skin damage2012
- Author(s)
  Hama S, Takahashi K, Inai Y, Shiota K, Sakamoto R, Yamada A, Tsuchiya H, Kanamura K, Yamashita E, Kogure K
- Journal Title
  
  J Pharm Sci
  
  Volume: Vol.101 Issue: 8 Pages: 2909-2916
- DOI
  10.1002/jps.23216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390014
[Journal Article] Noninvasive and efficient transdermal delivery of CpG-oligodeoxynucleotide for cancer immunotherapy2011
- Author(s)
  Kigasawa K, Kajimoto K, Nakamura T, Hama S, Kanamura K, Harashima H, Kogure K
- Journal Title
  
  J. Control. Release
  
  Volume: 150 Pages: 256-265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790049
[Journal Article] Noninvasive and efficient transdermal delivery of CpG-oligodeoxynucleotide for cancer immunotherapy2011
- Author(s)
  Kigasawa K, Kajimoto K, Nakamura T, Hama S, Kanamura K, Harashima H, Kogure K
- Journal Title
  
  J.Control.Release.
  
  Volume: 150 Pages: 256-265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790049
[Journal Article] Sendai viral vector mediated angiopoietin-1 gene transfer for experimental ischemic limb disease.2009
- Author(s)
  Huang J, Inoue M, Hasegawa M, Tomihara K, Tanaka T, Chen J, Hamada H
- Journal Title
  
  Angiogenesis 12(3)
  
  Pages: 243-249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] Gene transfer of CD40-ligand to dendritic cells stimulates interferon-γproduction to induce growth arrest and apoptosis of tumor cells.2008
- Author(s)
  Tomihara K, Kato K, Masuta Y, Nakamura K, Uchida H, Sasaki K, Tanaka T, Huang J, Hiratsuka H, Hamada H
- Journal Title
  
  Gene Therapy 15
  
  Pages: 203-213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] Selective gene transfer into neurons via Na, K-ATPase beta1. Targeting gene transfer with monoclonal antibody and adenovirus vector.2008
- Author(s)
  Ishii K, Nakamura K, Kawaguchi S, Li R, Hirai S, Sakuragi N, Wada T, Kato K, Yamashita T, Hamada H
- Journal Title
  
  J. Gene Med. 10(6)
  
  Pages: 597-609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] E1A, E1B double-restricted adenovirus with RGD-fiber modification exhibits enhanced oncolysis for CAR-deficient biliary cancers.2007
- Author(s)
  Wakayama M, Abei M, Kawashima R, Seo E, Fukuda K, Uqai H, Murata T, Tanaka N, Hyodo I, Hamada H, Yokoyama K
- Journal Title
  
  Clin. Cancer Res. 13(10)
  
  Pages: 3043-3050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] Gene transfer of the CD40-ligand to human dendritic cells induces NK-mediated antitumor effects against human carcinoma cells.2007
- Author(s)
  Tomihara K, Kato K, Masuta Y, Nakamura K, Tanaka T, Hiratsuka H, Hamada H
- Journal Title
  
  Int. J. Cancer 120(7)
  
  Pages: 1491-1498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] Gene transfer of noncleavable cell surface mutants of human CD154 induces the immune response and diminishes systemic inflammatory reactions.2007
- Author(s)
  Masuta Y, Kato K, Tomihara K, Nakamura K, Sasaki K, Takahashi S, Hamada H
- Journal Title
  
  J. Immunother. 30(7)
  
  Pages: 694-704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload.2007
- Author(s)
  Sano M.et al., Hamada H.
- Journal Title
  
  Nature 446(7134)
  
  Pages: 444-448
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] Gene transfer of the CD40-ligand to human dendritic cells induces NK-mediated antitumor effects against human carcinoma cells.2007
- Author(s)
  Tomihara K, Hamada H.
- Journal Title
  
  Int.J.Cancer 120(7)
  
  Pages: 1491-1498
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload.2007
- Author(s)
  Sano M, Minamino T, Toko H, Miyauchi H, Orimo M, Qin Y, Akazawa H, Tateno K, Kayama Y, Harada M, Shimizu I, Asahara T, Hamada H, Tomita S, Molkentin JD, Zou Y, Komuro I
- Journal Title
  
  Nature 446(7134)
  
  Pages: 444-448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] Oncolytic replication-competent adenovirus suppresses tumor angiogenesis through preserved E1A region.2006
- Author(s)
  Saito Y.et al., Hamada H.
- Journal Title
  
  Cancer Gene Therapy 13
  
  Pages: 242-252
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] Detailed characterization of the mouse glioma 261 tumor model for experimental glioblastoma therapy.2006
- Author(s)
  Szatm, aacute, ri T. et al., Hamada H.
- Journal Title
  
  Cancer Science 97(6)
  
  Pages: 546-553
- NAID
  10018176511
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] Ex vivo large scale generation of human platelets from cord blood CD34+cells.2006
- Author(s)
  Matsunaga T.et al., Hamada H.
- Journal Title
  
  Stem Cells 24(12)
  
  Pages: 2877-2887
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] Carcinoembryonic antigen targeted selective genetherapy for gastric cancer through FZ33 fiber-modified adenovirus vectors.2006
- Author(s)
  Tanaka T.et al., Hamada H.
- Journal Title
  
  Clinical Cancer Research 12(12)
  
  Pages: 3803-3813
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] Carcinoembryonic antigen targeted selective genetherapy for gastric cancer through FZ33 fiber-modified adenovirus vectors.2006
- Author(s)
  Tanaka T, Huang J, Hirai S, Kuroki M, Watanabe N, Tomihara K, Kato K, Hamada H
- Journal Title
  
  Clinical Cancer Research 12(12)
  
  Pages: 803-3813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion.2005
- Author(s)
  Sato Y.et al., Hamada H.
- Journal Title
  
  Blood 106(2)
  
  Pages: 756-763
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] Mesenchymal stem cells that produce neurotrophic factors reduce ischemic damage in the rat middle cerebral artery occlusion model.2005
- Author(s)
  Kurozumi K, Nakamura K, Tamiya T, Kawano Y, Ishii K, Kobune M, Hirai S, Uchida H, Sasaki K, Ito Y, Kato K, Honmou O, Houkin K, Date I, Hamada H
- Journal Title
  
  Mol. Ther. 11(1)
  
  Pages: 96-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] Enhanced osteoinduction by mesenchymal stem cells transfected with a fiber-mutant adenoviral BMP2 gene.2005
- Author(s)
  Tsuda H.et al., Hamada H.
- Journal Title
  
  J Gene Med. 7(10)
  
  Pages: 1322-1334
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] Bcl-xL gene transfer inhibits Bax translocation and prolongs cardiac cold reservation time in rat.2005
- Author(s)
  Huang J.et al., Hamada H.
- Journal Title
  
  Circulation 112(1)
  
  Pages: 76-83
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] Mesenchymal stem cells that produce neurotrophic factors reduce ischemic damage in the rat middle cerebral artery occlusion model.2005
- Author(s)
  Kurozumi K.et al., Hamada H.
- Journal Title
  
  Mol Ther. 11(1)
  
  Pages: 96-104
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] Effective gene therapy of biliary tract cancers by a conditionally replicative adenovirus expressing uracil phosphoribosyltransferase: significance of timing of 5-fluorouracil administration.2005
- Author(s)
  Seo E, Abei M, Wakayama M, Fukuda K, Ugai H, Murata T, Todoroki T, Matsuzaki Y, Tanaka N, Hamada H, Yokoyama K
- Journal Title
  
  Cancer Res. 65(2)
  
  Pages: 546-552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] Effective gene therapy of biliary tract cancers by a conditionally replicative adenovirus expressing uracil phosphoribosyltransferase : significance of timing of 5-fluorouracil administration.2005
- Author(s)
  Seo E.et al., Hamada H.
- Journal Title
  
  Cancer Res. 65(2)
  
  Pages: 546-552
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] Expansion of CD34+ cells on telomerized human stromal cells without losing erythroid-differentiation potential in a serum-free condition.2005
- Author(s)
  Kobune M.et al., Hamada H.
- Journal Title
  
  Int J Hematol. 81(1)
  
  Pages: 18-25
- NAID
  10014282469
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] Enhanced osteoinduction by mesenchymal stem cells transfected with a fiber-mutant adenoviral BMP2 gene.2005
- Author(s)
  Tsuda H, Wada T, Yamashita T, Hamada H
- Journal Title
  
  J. Gene Med. 7(10)
  
  Pages: 1322-1334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] Bcl-xL gene transfer inhibits Bax translocation and prolongs cardiac cold preservation time in rat.2005
- Author(s)
  Huang J, Nakamura K, Ito Y, Uzuka T, Morikawa M, Hirai S, Tomihara K, Tanaka T, Masuta Y, Ishii K, Kato K, Hamada H
- Journal Title
  
  Circulation 112(1)
  
  Pages: 76-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016059
[Journal Article] Development of a Novel Drug Delivery System consisting of an Antitumor Agent Tocopheryl Succinate
- Author(s)
  Hama S, Utsumi S, Fukuda Y, Nakayama K, Okamura Y, Tsuchiya H, Fukuzawa K, Harashima H, Kogure K
- Journal Title
  
  J. Control. Release
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790049
[Journal Article] Prevention of Tumor Growth by Needle-free Jet Injection of anti-C7orf24 siRNA
- Author(s)
  Hama S, Arata M, Nakamura I, Kasetani T, Itakura S, Tsuchiya S, Yoshiki T, Kogure K
- Journal Title
  
  Cancer Gene Ther
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790049
[Patent] 弱酸性ｐＨ応答性ペプチド及び該ペプチドを含むリポソーム2013
- Inventor(s)
  小暮健太朗　濱進
- Industrial Property Rights Holder
  小暮健太朗　濱進
- Industrial Property Rights Type
  特許
- Filing Date
  2013-10-22
- Overseas
- Data Source
  KAKENHI-PROJECT-25860030
[Patent] pH応答性ペプチドを含むナノ粒子2012
- Inventor(s)
  小暮健太朗, 濱進
- Industrial Property Rights Holder
  大鵬薬品工業株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2012-11-01
- Overseas
- Data Source
  KAKENHI-PROJECT-23390014
[Patent] pH応答性ペプチドを含むナノ粒子2012
- Inventor(s)
  小暮健太朗、濱進
- Industrial Property Rights Holder
  大鵬薬品工業株式会社
- Filing Date
  2012-04-24
- Overseas
- Data Source
  KAKENHI-PROJECT-21790049
[Patent] pH応答性ペプチドを含むナノ粒子2012
- Inventor(s)
  小暮健太朗、濱進
- Industrial Property Rights Holder
  大鵬薬品工業株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2012-11-01
- Overseas
- Data Source
  KAKENHI-PROJECT-23390014
[Patent] pH応答性ペプチドを含むナノ粒子2011
- Inventor(s)
  小暮健太朗, 濱進
- Industrial Property Rights Holder
  大鵬薬品工業株式会社
- Industrial Property Number
  2011-097694
- Filing Date
  2011-04-25
- Data Source
  KAKENHI-PROJECT-21790049
[Patent] pH応答性ペプチドを含むナノ粒子2011
- Inventor(s)
  小暮健太朗, 濱進
- Industrial Property Rights Holder
  大鵬薬品工業株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2011-097694
- Filing Date
  2011-04-25
- Data Source
  KAKENHI-PROJECT-23390014
[Patent] pH応答性ペプチドを含むナノ粒子2011
- Inventor(s)
  小暮健太朗、濱進
- Industrial Property Rights Holder
  大鵬薬品工業株式会社
- Industrial Property Number
  2011-097694
- Filing Date
  2011-04-05
- Data Source
  KAKENHI-PROJECT-23390014
[Patent] IL-13Ra2に対する抗体およびこれを含む診断・治療薬2009
- Inventor(s)
  濱田洋文、加藤和則、中村公則
- Industrial Property Rights Holder
  札幌医大
- Industrial Property Number
  2007-147478
- Filing Date
  2009-06-01
- Data Source
  KAKENHI-PROJECT-17016059
[Patent] PAP2aに対する抗体ならびにその診断的および治療的使用2008
- Inventor(s)
  濱田洋文、加藤和則、中村公則
- Industrial Property Rights Holder
  札幌医大
- Acquisition Date
  2008-03-21
- Data Source
  KAKENHI-PROJECT-17016059
[Patent] PAP2aに対する抗体ならびにその診断的および治療的使用2008
- Inventor(s)
  濱田加藤中村
- Industrial Property Rights Holder
  札幌医大
- Acquisition Date
  2008-03-21
- Data Source
  KAKENHI-PROJECT-17016059
[Patent] 抗CEA抗体を用いた標的化遺伝子治療2007
- Inventor(s)
  濱田洋文、田中俊裕、加藤和則, ら
- Industrial Property Rights Holder
  札幌医大
- Industrial Property Number
  2005-208800
- Filing Date
  2007-07-19
- Data Source
  KAKENHI-PROJECT-17016059
[Patent] PAP2aに対する抗体ならびにその診断的および治療的使用2007
- Inventor(s)
  濱田加藤中村
- Industrial Property Rights Holder
  札幌医大
- Filing Date
  2007-12-10
- Overseas
- Data Source
  KAKENHI-PROJECT-17016059
[Patent] PAP2aに対する抗体ならびにその診断的および治療的使用2006
- Inventor(s)
  濱田, 加藤, 中村
- Industrial Property Rights Holder
  北海道
- Filing Date
  2006
- Data Source
  KAKENHI-PROJECT-17016059
[Presentation] 抗癌ナノ粒子の細胞内動態制御による薬剤耐性癌における細胞死の増強2024
- Author(s)
  虎谷愛絵理、川崎楓、五十嵐澄佳、山崎裕一、濱　進
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K11858
[Presentation] 新規血中滞留性素子で修飾された腫瘍微小環境応答性リポソームの開発2024
- Author(s)
  森本慧、板倉祥子、佐藤智子、井部小夏、山崎裕一、濱　進
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K11858
[Presentation] 腫瘍深部の微弱低pH下の癌細胞へ薬物送達可能な腫瘍透過性リポソームの開発2024
- Author(s)
  北村果鈴、山崎裕一、濱　進
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K11858
[Presentation] トコフェロールコハク酸はアンジオポエチン2の発現抑制を介して腫瘍血管を安定化する2023
- Author(s)
  濱　進
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K11858
[Presentation] ドキソルビシン耐性癌の克服を目指したトコフェロールコハク酸ナノ粒子の開発2023
- Author(s)
  川崎楓、磯野永太朗、山崎裕一、濱　進
- Organizer
  第39回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-23K11858
[Presentation] 腫瘍低pH応答性リポソームの表面改質による血中滞留性の向上2020
- Author(s)
  濱　進、板倉祥子、前田静香、丸川裕己、宗慶太郎
- Organizer
  第36回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03540
[Presentation] 新規血中滞留性素子を修飾した腫瘍微小環境応答性リポソームの開発2019
- Author(s)
  濱　進、板倉祥子、宗慶太郎
- Organizer
  第41回日本バイオマテリアル学会
- Data Source
  KAKENHI-PROJECT-18H03540
[Presentation] ポリエチレングリコール修飾リポソームと微弱低pH応答性ペプチド修飾リポソームの血中滞留性の比較2019
- Author(s)
  渡邊優哉，中山佳代子，中井麻友美，丸川裕己，小暮健太朗，濱進
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18H03540
[Presentation] 血中滞留性と腫瘍低pH応答性を併せ持つDDSの開発2019
- Author(s)
  濱　進、丸川裕己、板倉祥子、宗慶太郎
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03540
[Presentation] Tumor-penetrable nanoparticles for delivering drugs into cells in response to tumor microenvironment.2018
- Author(s)
  Hama S, Suzuki S, Itakura S, Kogure K
- Organizer
  BIT's 8th Annual World Congress Of Nano Science and Technology 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0357
[Presentation] 微弱低pH応答性リポソームの腫瘍内透過におけるiRGD修飾の影響2018
- Author(s)
  板垣渚、松井　諒、板倉　祥子、濱　進
- Organizer
  日本薬剤学会　第33年会
- Data Source
  KAKENHI-PROJECT-15KK0357
[Presentation] 腫瘍深部の微弱低pH下のがん細胞へ薬物送達可能な腫瘍透過性リポソームの開発2018
- Author(s)
  板垣　渚，松井　諒，板倉祥子，斎藤博幸，濱　進
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K07907
[Presentation] 新規血中滞留性素子を搭載した腫瘍低pH応答性リポソームの開発2018
- Author(s)
  丸川裕己、板倉祥子、斎藤博幸、宗慶太郎、濱進
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15KK0357
[Presentation] Development of a tumor-penetrable drug carrier in response to tumor microenvironment.2018
- Author(s)
  Hama S, Itakura S
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15KK0357
[Presentation] Development of a siRNA Carrier Penetrable into the Deep Region of Tumor2018
- Author(s)
  Hama S, Itakura S, Kogure K
- Organizer
  BIT's 9th World Gene Convention 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03540
[Presentation] 微弱低pH 応答性薬物キャリアーの腫瘍内透過促進2017
- Author(s)
  板垣渚，松井諒，斎藤博幸，小暮健太朗，濱進
- Organizer
  第67回日本薬学会近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-15K07907
[Presentation] 腫瘍内透過性と微弱低pH応答性を併せ持つ薬物キャリアーの開発.2016
- Author(s)
  松井諒、濱進、鈴木智子、板倉祥子、小暮健太朗、斎藤博幸
- Organizer
  第32回日本DDS学会学術集会
- Place of Presentation
  静岡
- Year and Date
  2016-06-30
- Data Source
  KAKENHI-PROJECT-15K07907
[Presentation] 腫瘍深部への薬物送達が可能な微小環境応答性リポソームの開発.2016
- Author(s)
  松井諒、鈴木智子、小暮健太朗、斎藤博幸、濱　進
- Organizer
  第66回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-15K07907
[Presentation] Slightly Acidic pH Sensitive Peptide-Modified Nanoparticles for Nucleic Acid Delivery to Cancer Cells.2016
- Author(s)
  Hama S, Itakura S, Kogure K
- Organizer
  BIT’s 6th Annual World Congress of Nano Science & Technology-2016
- Place of Presentation
  シンガポール
- Year and Date
  2016-10-26
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07907
[Presentation] 電荷反転型ペプチドによる癌治療DDSからのsiRNAの効率的な細胞質放出.2016
- Author(s)
  濱進、板倉祥子
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K07907
[Presentation] 微小環境応答性ドラッグデリバリーシステムの腫瘍内透過性の改善.2016
- Author(s)
  松井諒、鈴木智子、板倉祥子、小暮健太朗、斎藤博幸、濱進
- Organizer
  第14回がんとハイポキシア研究会
- Place of Presentation
  岐阜
- Year and Date
  2016-11-04
- Data Source
  KAKENHI-PROJECT-15K07907
[Presentation] Development of liposomal siRNA carriers using slightly acid pH-sensitive peptide SAPSP for cancer therapy.2016
- Author(s)
  Hama S, Itakura S, Matsui R, Kogure K
- Organizer
  3rd International Conference on Biomaterials Science in Tokyo
- Place of Presentation
  東京
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07907
[Presentation] pH応答性ペプチドSAPSpから構成される核酸凝集体をコアとする核酸キャリアーからのsiRNA放出促進．2015
- Author(s)
  濱進、板倉祥子、松井諒、小暮健太朗
- Organizer
  第31回日本DDS学会学術集会
- Place of Presentation
  東京
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-15K07907
[Presentation] がん微小環境応答性素子を組み込んだリポソーム型DDSの構築．2015
- Author(s)
  濱進、板倉祥子、小暮健太朗
- Organizer
  第37回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  熊本
- Year and Date
  2015-11-19
- Invited
- Data Source
  KAKENHI-PROJECT-15K07907
[Presentation] 腫瘍低pH応答性ペプチドSAPSp修飾リポソームのアクチン脱重合を介した腫瘍内透過．2015
- Author(s)
  鈴木智子、濱進、板倉祥子、中山佳代子、小暮健太朗
- Organizer
  第31回日本DDS学会学術集会
- Place of Presentation
  東京
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-15K07907
[Presentation] 細胞質環境に応答して電荷が反転するペプチドを用いた核酸放出システムの開発．2015
- Author(s)
  松井諒、板倉祥子、濱進、小暮健太朗
- Organizer
  遺伝子・デリバリー研究会第15回シンポジウム
- Place of Presentation
  京都
- Year and Date
  2015-05-01
- Data Source
  KAKENHI-PROJECT-15K07907
[Presentation] Lipocalin2 stabilizes hypoxia inducible factor-in through the iron delivery into normoxic cancer cells．2015
- Author(s)
  Susumu Hama, Ibuki Nakamura, Akinori Nishimoto, Takayuki Nishi, Shoko Itakura, Kentaro Kogure
- Organizer
  AACR-NCI-EORTC INTERNATIONAL CONFERENCE MOLECULAR TARGETS AND CANCER THERAPEUTICS
- Place of Presentation
  Boston, USA
- Year and Date
  2015-11-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07907
[Presentation] 腫瘍低pH応答性ペプチドSAPSp修飾リポソームの腫瘍内透過機構の解析．2015
- Author(s)
  鈴木智子、濱進、板倉祥子、中山佳代子、小暮健太朗
- Organizer
  遺伝子・デリバリー研究会第15回シンポジウム
- Place of Presentation
  京都
- Year and Date
  2015-05-01
- Data Source
  KAKENHI-PROJECT-15K07907
[Presentation] pH応答性ナノ粒子の効率的な細胞質送達メカニズムの解析2013
- Author(s)
  濱　進
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都府京都市
- Data Source
  KAKENHI-PROJECT-23390014
[Presentation] 腫瘍内部への浸透を目指した新規siRNA キャリアーの開発2013
- Author(s)
  宇野晃平, 鄭賢卿, 濱進, 小暮健太朗
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23390014
[Presentation] 腫瘍低pH応答性ナノ粒子の効率的な細胞質送達メカニズムの解析2013
- Author(s)
  濱進, 板倉祥子, 中井麻友美, 中山佳代子, 森本智士, 小暮健太朗
- Organizer
  第29回日本DDS 学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23390014
[Presentation] 腫瘍集積性向上のための腫瘍微弱低pH応答性リポソームの改良と機能性評価2013
- Author(s)
  森本智士, 濱進, 板倉祥子, 中井麻友美, 中山佳代子, 土谷博之, 小暮健太朗
- Organizer
  第29回日本DDS 学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23390014
[Presentation] 腫瘍の微弱低pH に応答して細胞内取り込みが促進されるSAPS ペプチド修飾ナノ粒子の機能性評価2013
- Author(s)
  中山佳代子, 濱進, 板倉祥子, 中井麻友美, 森本智士, 大石利一, 土谷博之, 小暮健太朗
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23390014
[Presentation] 柔軟な構造を有する組織浸透性siRNA キャリアーの開発2013
- Author(s)
  小暮健太朗, 鄭賢卿, 宇野晃平, 島谷悠里, 濵進
- Organizer
  第23回アンチセンスシンポジウム
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-23390014
[Presentation] Efficient cytoplasmic delivery of siRNA by tumoral pH sensitive nanoparticles via membrane fusion under tumor microenvironment2013
- Author(s)
  Itakura S. Hama S. Nakai M. Nakayama K. Morimoto S. Tsuchiya H. Kogure K
- Organizer
  40th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Hawaii, U.S.A
- Data Source
  KAKENHI-PROJECT-23390014
[Presentation] A flexible nano carrier for siRNA delivery into tumor2013
- Author(s)
  Kogure K. Shimatani Y. Uno K. Chon H.K. Hama S
- Organizer
  40th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Hawaii, U.S.A
- Data Source
  KAKENHI-PROJECT-23390014
[Presentation] 腫瘍環境の微弱なpH に応答するペプチドを用いた薬物キャリアーの開発2012
- Author(s)
  板倉祥子, 濱進, 中井麻友美, 中山佳代子, 森本智士, 大石利一, 土谷博之, 小暮健太朗
- Organizer
  第62回日本薬学会近畿支部総会・大会
- Place of Presentation
  兵庫
- Data Source
  KAKENHI-PROJECT-23390014
[Presentation] 抗癌剤トコフェロールコハク酸を用いた新規ドラッグデリバリーシステムの開発2012
- Author(s)
  濱進, 土谷博之, 小暮健太朗
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23390014
[Presentation] 組織狭小空間への送達を目指したsiRNA キャリアーの開発2012
- Author(s)
  小暮健太朗, 島谷悠里, 宇野晃平, 土谷博之, 濱進
- Organizer
  第28回日本DDS 学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23390014
[Presentation] 抗癌剤トコフェロールコハク酸を用いた新規ドラッグデリバリーシステムの開発2012
- Author(s)
  濱進
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  北海道札幌市
- Data Source
  KAKENHI-PROJECT-23390014
[Presentation] Development of a novel drug delivery system for combination therapy in cancer2012
- Author(s)
  Hama S. Utsumi S. Nakayama K. Okamura Y. Tsuchiya H. Fukuzawa K. Harashima H. Kogure K
- Organizer
  第6回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23390014
[Presentation] Develpopment of nobel tumoral pH responsive nanoparticles for cancer therapy2012
- Author(s)
  Hama S. Itakura S. Nakai M. Nakayama K, Morimoto S. Tsuchiya H. Kogure K
- Organizer
  the 39th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Quebec city, Canada
- Data Source
  KAKENHI-PROJECT-23390014
[Presentation] 細胞内動態に着目したトコフェロールコハク酸ナノ粒子の作用増強機構の解析2012
- Author(s)
  濱進
- Organizer
  第22回ビタミンE研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21790049
[Presentation] Development of a novel drug delivery system for combination therapy in cancer2012
- Author(s)
  Hama S.
- Organizer
  第６回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  京都府京都市
- Data Source
  KAKENHI-PROJECT-23390014
[Presentation] 癌治療のための微弱pH 変化応答性薬物キャリアの開発2012
- Author(s)
  森本智士, 濱進, 板倉祥子, 中井麻友美, 中山佳代子, 土谷博之, 小暮健太朗
- Organizer
  第28回日本DDS 学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23390014
[Presentation] ナノ粒子の膜物性制御による腫瘍低pH下の癌細胞への効率的な薬物送達2011
- Author(s)
  濱進
- Organizer
  第9回がんとハイポキシア研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390014
[Presentation] 抗癌活性を有するビタミンE誘導体を利用したナノ粒子の開発2011
- Author(s)
  濱進
- Organizer
  第17回国際癌治療増感研究会
- Place of Presentation
  宮城
- Data Source
  KAKENHI-PROJECT-21790049
[Presentation] Development of a flexible siRNA carrier penetrable into tumor2011
- Author(s)
  Kogure K, Shimatani Y, Uno K, Hama S
- Organizer
  the IUMRS-ICA 2011, 12th International Conferenee in Asia
- Place of Presentation
  Taipei World Trade Center Nangang Exhibition Hall (TWTC Nangang)(台湾)(招待講演)
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-23390014
[Presentation] 腫瘍環境応答性ナノキャリアーの開発2011
- Author(s)
  小暮健太朗, 板倉祥子, 中井麻由美, 中山佳代子, 森本智士, 濱進
- Organizer
  第33回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23390014
[Presentation] ナノ粒子の膜物性制御による腫瘍低pH下の癌細胞への効率的な薬物送達2011
- Author(s)
  濱進
- Organizer
  第9回がんとハイポキシア研究会
- Place of Presentation
  学習院大学(東京)
- Year and Date
  2011-11-26
- Data Source
  KAKENHI-PROJECT-23390014
[Presentation] 核酸医薬を封入したトコフェロールコハク酸ナノ粒子の機能性評価2011
- Author(s)
  濱進
- Organizer
  日本ビタミン学会第63回大会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-21790049
[Presentation] 腫瘍環境応答性ナノキャリアーの開発2011
- Author(s)
  小暮健太朗、板倉祥子、中井麻由美、中出佳代子、森本智士、濱進
- Organizer
  第33回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  岡山大学(岡出)
- Year and Date
  2011-11-24
- Data Source
  KAKENHI-PROJECT-23390014
[Presentation] ナノ粒子の膜物性制御による腫瘍低pH下の癌細胞への効率的な薬物送達2011
- Author(s)
  濱進
- Organizer
  第9回がんとハイポキシア研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21790049
[Presentation] Development of a flexible siRNA carrier penetrable into tumor2011
- Author(s)
  Kogure K, Shimatani Y, Uno K, Hama S
- Organizer
  the IUMRS-ICA 2011, 12th International Conference in Asia
- Place of Presentation
  台湾
- Data Source
  KAKENHI-PROJECT-23390014
[Presentation] Suppression of Tumor Grouth by Nanoparticles consisting of α-Tocopheryl Succinate2011
- Author(s)
  濱進
- Organizer
  The Third International Conference on Cofactors(ICC-03)
- Place of Presentation
  Turku, Finland
- Data Source
  KAKENHI-PROJECT-21790049
[Presentation] 腫瘍の低pH環境に応答して細胞親和性が向上する薬物キャリアーの開発2010
- Author(s)
  濱進
- Organizer
  遺伝子・デリバリー研究会第10回シンポジウム
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21790049
[Presentation] 低酸素環境下の癌細胞に対する抗体の機能性評価2010
- Author(s)
  濱進
- Organizer
  日本薬剤学会第25年会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21790049
[Presentation] がん微小環境を利用した癌治療・診断法の開発2010
- Author(s)
  濱進
- Organizer
  ナノライフサイエンス・オープンセミナー2010
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21790049
[Presentation] 腫瘍の低pH環境に応答して細胞親和性が向上する薬物キャリアーの開発2010
- Author(s)
  濱進
- Organizer
  遺伝子・デリバリー研究会第10回シンポジウム
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21790049
[Presentation] 低酸素環境下の癌認識抗体の機能性評価2010
- Author(s)
  濱進
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21790049
[Presentation] 低酸素環境下の癌細胞を認識する抗体の樹立と機能性評価2010
- Author(s)
  濱進
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21790049
[Presentation] 腫瘍標的遺伝子治療2009
- Author(s)
  濱田洋文
- Organizer
  第68回日本癌学会学術総会教育講演モーニングレクチャー
- Place of Presentation
  横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-17016059
[Presentation] 膵がんに対する遺伝子治療の展望2009
- Author(s)
  濱田洋文
- Organizer
  第68回日本癌学会学術総会シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-17016059
[Presentation] 腫瘍の特異的標的化を目指した遺伝子治療法の開発2008
- Author(s)
  濱田洋文
- Organizer
  第3次対がん10か年総合戦略、第2回合同シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-02-28
- Data Source
  KAKENHI-PROJECT-17016059
[Presentation] 臓器がん-膵癌「新たな膵癌抗原の探索」2006
- Author(s)
  濱田洋文
- Organizer
  日本癌学会総会シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2006-09-30
- Data Source
  KAKENHI-PROJECT-17016059
[Presentation] 遺伝子治療現状と近未来腫瘍の標的化を目指した遺伝子治療の開発2005
- Author(s)
  濱田洋文
- Organizer
  日本癌学会総会教育講演
- Place of Presentation
  札幌
- Year and Date
  2005-09-16
- Data Source
  KAKENHI-PROJECT-17016059
[Presentation] 微弱低pH応答性ペプチドSAPSp修飾ナノ粒子の腫瘍内透過メカニズムの解析
- Author(s)
  鈴木智子、濱進、板倉祥子、中井麻由美、中山佳代子、森本智士、小暮健太朗
- Organizer
  第36回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  徳島
- Year and Date
  2014-11-20 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-25860030
[Presentation] 腫瘍内底pH応答性ペプチドを利用した薬物放出キャリアーの開発
- Author(s)
  濱進、大石利一、板倉祥子、小暮健太朗
- Organizer
  第36回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  徳島
- Year and Date
  2014-11-20 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-25860030
[Presentation] 腫瘍微小環境に応答する新規ペプチドを修飾したナノ粒子はポリエチレングリコールのジレンマを克服する
- Author(s)
  濱進、小暮健太朗
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25860030
[Presentation] 腫瘍内動態制御可能な低pH応答性ペプチド修飾薬物キャリアーの開発
- Author(s)
  濱　進、板倉祥子、鈴木智子、中山佳代子、森本智士、小暮健太朗
- Organizer
  第33回分子病理研究会
- Place of Presentation
  宮城
- Year and Date
  2014-07-25 – 2014-07-26
- Data Source
  KAKENHI-PROJECT-25860030

1. HAMADA Hirohumi (00189614)

# of Collaborated Projects: 2 results

# of Collaborated Products: 30 results
2. KOGURE Kentaro (70262540)

# of Collaborated Projects: 2 results

# of Collaborated Products: 34 results
3. HASAN Mahadi

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KATO Kazunori (60233780)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. NAKAMURA Kiminori (80381276)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
6. YAMAGUCHI Miki (10530454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TSUCHIY Hiroyuki (00403402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
8. 牧野宏章 (40784369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Itagaki Nagisa

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. Marukawa Hiroki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. Watanabe Yuya

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Kamei Kazuho

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Maeda Shizuka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KIRIMURA Naoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SUZUKI Satoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
16. NiSHI Takayuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
17. MATSUI Ryo

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
18. Kopecek Jindrich

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 原島秀吉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hama Susumu 濱 進

濱 進 ハマ ススム

HAMA Susumu 濱 進

Research Projects

Research Products

Co-Researchers

Control of tumor microenvironment by lipid nanoparticles modified with novel blood-circulating moleculesPrincipal Investigator

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Improvement of the surface properties of nanoparticles by using a novel stealth device and their application to nucleic acid carrier controlling tumor microenvironment.Principal Investigator

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Development of nucleic acids carriers equipped with tumor microenvironment-sensitive peptides for the therapy of metastatic liver cancer(Fostering Joint International Research)Principal Investigator

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Development of nucleic acids carriers equipped with tumor microenvironment-sensitive peptides for the therapy of metastatic liver cancerPrincipal Investigator

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Development of slightly acidic pH-sensitive nanoparticles being capable of size-selective drug release for cancer therapy and diagnosisPrincipal Investigator

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Development of a novel type worm-like DDS penetrable into tumor tissue

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Development of tumor microenvironment responsive nanoparticles and investigation of the antitumor effectPrincipal Investigator

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Development of gene therapy and sensitive diagnostic method using an antibody for hypoxic breast cancerPrincipal Investigator

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Selective targeted drug and gene delivery for cancer treatment

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[Book] DDS先端技術の製剤への応用開発2017

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[Book] Stem Cell Repair and Regeneration2005

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[Journal Article] Develop liposome-based drug carriers in response to tumour microenvironment2018

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[Journal Article] Tumor Microenvironment-Sensitive Liposomes Penetrate Tumor Tissue via Attenuated Interaction of the Extracellular Matrix and Tumor Cells and Accompanying Actin Depolymerization.2017

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[Journal Article] Effective cytoplasmic release of siRNA from liposomal carriers by controlling the electrostatic interaction of siRNA with a charge-invertible peptide, in response to cytoplasmic pH.2016

Author(s)

Hama Susumu 濱進

濱進ハマススム

HAMA Susumu 濱進