Naruto Takuya 成戸卓也

… Alternative Names

NARUTO Takuya 成戸卓也

Less

Researcher Number	60438124
Other IDs
Affiliation (Current)	2025: 地方独立行政法人神奈川県立病院機構神奈川県立こども医療センター(臨床研究所), 臨床研究所, 主任研究員 2025: 東京科学大学, その他の部局等, 非常勤講師
Affiliation (based on the past Project Information) *help	2025: 地方独立行政法人神奈川県立病院機構神奈川県立こども医療センター(臨床研究所), 臨床研究所, 主任研究員 2021 – 2023: 地方独立行政法人神奈川県立病院機構神奈川県立こども医療センター(臨床研究所), 臨床研究所, 主任研究員 2019 – 2020: 東京医科歯科大学, 大学院医歯学総合研究科, プロジェクト研究員 2016 – 2018: 東京医科歯科大学, 大学院医歯学総合研究科, プロジェクト助教 2016: 徳島大学, 大学院医歯薬学研究部人類遺伝学, 助教 … More 2015: 徳島大学, 大学院医歯薬学研究部, 助教 2008: Kumamoto University, エイズ学研究センター, 非常勤研究員 2007 – 2008: Yokohama City University, 医学研究科, 博士研究員 2007: 横浜市立大学, 医学部, 博士研究員 2006: Yokohama City University, Medical Department, Researcher, 医学部, 研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics Except Principal Investigator Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords	Principal Investigator 川崎病冠動脈病変 / 冠動脈炎 / 川崎病 / イントロン変異 / スプライス変異 / スプライシング変異 / 小児急性リンパ性白血病 / CRLF2 / 代謝性疾患 / MVK / メバロン酸 / 高IgD症候群 / 自己炎症症候群 … More Except Principal Investigator … More IL-6 / 薬剤感受性 / トランスクリプトーム解析 / 3次元培養 / 患者由来疾患モデル / 悪性ラブドイド腫瘍 / 次世代シーケンサー / エクソーム / copy number variant / ゲノム支援 / マイクロアレイ / エクソーム解析 / 次世代シーケンス / 精神遅滞 / 多発奇形 / hypercytokine diseases / investigation for pathogenesis / anti IL-6 receptor antibody / juvenile idiopathic arthritis / DNAチップ / プロテオーム解析法 / 若年性特発性関節炎 / 高サイトカイン病 / 原因検索 / 抗IL-6レセプター抗体 / 若年性突発性関節炎 / Nod蛋白 / TLR蛋白 / cytokine storm / サイトカインストーム / 免疫疾患 / 乳幼児 / 自然免疫 / 炎症性サイトカイン / 軟骨細胞 / 成長板 Less

パンゲノムの構築による希少疾患のゲノム構造異常に伴う遺伝子発現調節機構の探索Principal Investigator
- Principal Investigator
  
  成戸卓也
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kanagawa Children's Medical Center (Clinical Research Institute)
Establishment of biomarkers and elucidation of pathophysiology for coronary artery lesions of Kawasaki diseasePrincipal Investigator
- Principal Investigator
  
  成戸卓也
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kanagawa Children's Medical Center (Clinical Research Institute)
Pathological analysis of malignant rhabdoid tumor by utilizing the human disease model library
- Principal Investigator
  
  後藤裕明
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kanagawa Children's Medical Center (Clinical Research Institute)
Elucidation of the molecular mechanism and development of therapeutic method of exon skip caused by mutationPrincipal Investigator
- Principal Investigator
  
  NARUTO TAKUYA
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kanagawa Children's Medical Center (Clinical Research Institute)
  Tokyo Medical and Dental University
CRLF2 over-expression analysis in precursor B-cell acute lymphoblastic leukemia in childrenPrincipal Investigator
- Principal Investigator
  
  NARUTO TAKUYA
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Tokyo Medical and Dental University
  The University of Tokushima
Genetic and genomic analysis on the patients with multiple congenital anomalies
- Principal Investigator
  
  Kurosawa Kenji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kanagawa Children's Medical Center (Clinical Research Institute)
TLR/Nod proteins in infants from dysregulation Pathological analysis Cytokine Storm
- Principal Investigator
  
  YOKOTA Shumpei
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Yokohama City University
Clarification of metabolic disorder and fever in hyper IgD syndromePrincipal Investigator
- Principal Investigator
  
  NARUTO Takuya
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kumamoto University
  Yokohama City University
The effect of inflammatory cytokines on the differentiation of chondrogenic progenitor cells in the growth plates
- Principal Investigator
  
  MORI Masaaki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Yokohama City University
Exhaustive analysis about juvenile idiopathic arthritis by using an anti-IL-6 receptor antibody
- Principal Investigator
  
  YOKOTA Shumpei
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Yokohama City University

All 2020 2019 2017 2016 2015 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Update of the genotype and phenotype of KMT2D and KDM6A by genetic screening of 100 patients with clinically suspected Kabuki syndrome2020
- Author(s)
  Murakami H, Tsurusaki Y, Enomoto K, Kuroda Y, Yokoi T, Furuya N, Yoshihashi H, Minatogawa M, Abe-Hatano C, Ohashi I, Nishimura N, Kumaki T, Enomoto Y, Naruto T, Iwasaki F, Harada N, Ishikawa A, Kawame H, Sameshima K, Yamaguchi Y, Kobayashi M, Tominaga M, Kuroki Y, Kurosawa K. et al.
- Journal Title
  
  American Journal of Medical Genetics Part A
  
  Volume: 182 Issue: 10 Pages: 2333-2344
- DOI
  10.1002/ajmg.a.61793
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07873, KAKENHI-PROJECT-18K07863
[Journal Article] A deep intronic mutation of c.1166-285?T?>?G in SLC46A1 is shared by four unrelated Japanese patients with hereditary folate malabsorption (HFM)2019
- Author(s)
  Tozawa Yusuke、Abdrabou Shimaa Said Mohamed Ali、Nogawa-Chida Natsuko、Nishiuchi Ritsuo、Ishida Toshiaki、Suzuki Yuichi、Sano Hideki、Kobayashi Ryoji、Kishimoto Kenji、Ohara Osamu、Imai Kohsuke、Naruto Takuya、Kobayashi Kunihiko、Ariga Tadashi、Yamada Masafumi
- Journal Title
  
  Clinical Immunology
  
  Volume: 208 Pages: 108256-108256
- DOI
  10.1016/j.clim.2019.108256
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07814, KAKENHI-PROJECT-18K07873, KAKENHI-PROJECT-16K20871
[Journal Article] A novel UBE2A mutation causes X-linked intellectual disability type Nascimento.2017
- Author(s)
  Tsurusaki Y, Ohashi I, Enomoto Y, Naruto T, Mitsui J, Kurosawa K, Aida N
- Journal Title
  
  Human Genome Variation
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461538
[Journal Article] Microdeletion of 19p13.3 in a girl with Peutz-Jeghers syndrome, intellectual disability, hypotonia, and distinctive features.2015
- Author(s)
  Kuroda Y, Saito T, Nagai J, Ida K, Naruto T, Masuno M, Kurosawa K
- Journal Title
  
  Am J Med Genet A
  
  Volume: 167A Issue: 2 Pages: 389-393
- DOI
  10.1002/ajmg.a.36813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461538
[Journal Article] Delineation of the KIAA2022 mutation phenotype: Two patients with X-linked intellectual disability and distinctive features.2015
- Author(s)
  Kuroda Y, Ohashi I, Naruto T, Ida K, Enomoto Y, Saito T, Nagai J, Wada T, Kurosawa K.
- Journal Title
  
  Ａｍ　Ｊ　Ｍｅｄ　Ｇｅｎｅｔ　Ａ
  
  Volume: 167 Issue: 6 Pages: 1349-53
- DOI
  10.1002/ajmg.a.37002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461538
[Journal Article] A postzygotic NRAS mutation in a patient with Schimmelpenning syndrome.2015
- Author(s)
  Kuroda Y, Ohashi I, Enomoto Y, Naruto T, Baba N, Tanaka Y, Aida N, Okamoto N, Niihori T, Aoki Y, Kurosawa K.
- Journal Title
  
  Am J Med Genet A.
  
  Volume: 167A Issue: 9 Pages: 2223-2225
- DOI
  10.1002/ajmg.a.37135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461520, KAKENHI-PROJECT-26461538
[Journal Article] Deletion of UBE3A in brothers with Angelman syndrome at the breakpoint with an inversion at 15q11.2.2015
- Author(s)
  Kuroda Y, Ohashi I, Saito T, Nagai JI, Ida K, Naruto T, Wada T, Kurosawa K
- Journal Title
  
  Am J Med Genet A
  
  Volume: 167A Issue: 11 Pages: 2873-2878
- DOI
  10.1002/ajmg.a.36704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461538
[Journal Article] West Syndrome in a Patient With Schinzel-Giedion Syndrome.2015
- Author(s)
  Miyake F, Kuroda Y, Naruto T, Ohashi I, Takano K, Kurosawa K.
- Journal Title
  
  J Child Neurol
  
  Volume: 30 Issue: 7 Pages: 932-6
- DOI
  10.1177/0883073814541468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461538
[Journal Article] Hyper-IgD syndrome with novel mutation in a Japanese girl2009
- Author(s)
  Naruto T.
- Journal Title
  
  Modern Rheumatology 1
  
  Pages: 96-99
- NAID
  10025112230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790735
[Journal Article] Hyper-IgD syndrome with novel mutation in a Japanese girl.2009
- Author(s)
  Takuya Naruto
- Journal Title
  
  Mod Rheumatol 19-1
  
  Pages: 96-99
- NAID
  10025112230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390287
[Journal Article] The role of heme oxygenase-1 in systemic-onset juvenile idiopathic arthritis.2009
- Author(s)
  Takahashi A, Mori M, Naruto T, Nakajima S, Miyamae T, Imagawa T, Yokota S
- Journal Title
  
  Mod Rheumatol. 19(3)
  
  Pages: 302-8
- NAID
  10025113098
- Data Source
  KAKENHI-PROJECT-19390287
[Journal Article] Hyper-IgD syndrome with novel mutation in a Japanese girl2009
- Author(s)
  Naruto T, Nakagishi Y, Mori M, Miyamae T, Imagawa T, Yokota S
- Journal Title
  
  Mod Rheumatol 19(1)
  
  Pages: 96-9
- NAID
  10025112230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790735
[Journal Article] Interleukin-6 inhibits early differentiation of ATDC5 chondrogenic progenitor cells2009
- Author(s)
  Shoko Nakajima, Takuya Naruto, Takako Miyamae, Tomoyuki Imagawa, Masaaki Mori, Shigeru Nishimaki, Shumpei Yokota
- Journal Title
  
  Cytokine (CYTO-09-49R1) (accepted, in print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591197
[Journal Article] 高IgD症候群のMVK遺伝子異常と新しい治療法の導入2007
- Author(s)
  成戸卓也
- Journal Title
  
  日本臨床免疫学会会誌 30
  
  Pages: 86-89
- NAID
  10019495258
- Data Source
  KAKENHI-PROJECT-19790735
[Journal Article] 高IgD症候群のMVK遺伝子異常と新しい治療法の導入2007
- Author(s)
  成戸卓也
- Journal Title
  
  日本臨床免疫学会会誌 30巻2号
  
  Pages: 86-89
- NAID
  10019495258
- Data Source
  KAKENHI-PROJECT-19790735
[Presentation] 次世代シーケンサーにより診断されたKBG症候群の臨床像2016
- Author(s)
  横井貴之、湊川真理、羽田野ちひろ、榎本友美、鶴崎美徳、成戸卓也、小崎健次郎、黒澤健司
- Organizer
  第39回日本小児遺伝学会
- Place of Presentation
  慶應義塾大学（東京都港区）
- Year and Date
  2016-12-09
- Data Source
  KAKENHI-PROJECT-26461538
[Presentation] Genetic analysis of autism spectrum disorder(ASD) based on developed diagnostic flows using next-generation sequencing (NGS).2015
- Author(s)
  Enomoto Y, Yokoi T, Hatano C, Ida K, Naruto T, Kurosawa K.
- Organizer
  米国人類遺伝学会2015
- Place of Presentation
  ボルチモア（米国）
- Year and Date
  2015-10-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461538
[Presentation] 遺伝性小児神経領域疾患診断への臨床エクソームの導入2015
- Author(s)
  羽田野ちひろ、横井貴之、渡邊肇子、露崎悠、新保裕子、榎本友美、成戸卓也、大橋育子、黒田友紀子、後藤知英、黒澤健司
- Organizer
  第57回日本小児神経学会学術集会
- Place of Presentation
  帝国ホテル大阪（大阪府大阪市北区）
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-26461538
[Presentation] EGFRの機能喪失型変異の複合ヘテロ接合を有する一男児例2015
- Author(s)
  横井貴之、羽田野ちひろ、鶴﨑美徳、榎本友美、成戸卓也、林至恩、小林正久、井田博幸、黒澤健司
- Organizer
  日本人類遺伝学会第60回大会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-10-14
- Data Source
  KAKENHI-PROJECT-26461538
[Presentation] 次世代シーケンサーを用いた遺伝性疾患におけるコピー数異常の検出．2015
- Author(s)
  横井貴之、大橋育子、黒田友紀子、羽田野ちひろ、榎本友美、成戸卓也、升野光雄、黒澤健司
- Organizer
  第39回日本遺伝カウンセリング学会学術集会
- Place of Presentation
  三井ガーデンホテル千葉（千葉県千葉市中央区）
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-26461538
[Presentation] 高IgD症候群2008
- Author(s)
  成戸卓也
- Organizer
  第29回日本炎症・再生医学会
- Place of Presentation
  東京
- Year and Date
  2008-07-10
- Data Source
  KAKENHI-PROJECT-19790735
[Presentation] 6p21.33 microdeletion associated with EHMT2 haploinsufficiency and intellectual disability.
- Author(s)
  Kurosawa K, Ohashi I, Kuroda Y, Naruto T, Saito T. J Nagai.
- Organizer
  European Human Genetics Conference 2014
- Place of Presentation
  Milan
- Year and Date
  2014-05-31 – 2014-06-02
- Data Source
  KAKENHI-PROJECT-26461538
[Presentation] 小児病院の診断における次世代シーケンサーの利用
- Author(s)
  榎本友美、大橋育子、黒田友紀子、羽田野ちひろ、横井貴之、井田一美、成戸卓也、黒澤健司
- Organizer
  第59回日本人類遺伝学会
- Place of Presentation
  東京
- Year and Date
  2014-11-20 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-26461538
[Presentation] メンデル遺伝病エクソーム解析による多発奇形・発達遅滞（MCA / ID・DD ）の解析
- Author(s)
  横井貴之、大橋育子、黒田友紀子、羽田野ちひろ、榎本友美、成戸卓也、升野光雄、井田博幸、黒澤健司
- Organizer
  第59回日本人類遺伝学会
- Place of Presentation
  東京
- Year and Date
  2014-11-20 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-26461538

1. IMAGAWA Tomoyuki (20336548)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
2. MORI Masaaki (30254204)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. YOKOTA Shumpei (10158363)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. Kurosawa Kenji (20277031)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
5. TSURUSAKI Yoshinori (70392040)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. ENOMOTO Yumi (20506290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
7. 片倉茂樹 (30347314)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 後藤裕明 (90347295)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 宮城洋平 (00254194)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 北河徳彦 (00585135)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 柳町昌克 (00608911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 大津敬 (10270696)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 田中祐吉 (50420691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 田中水緒 (60565232)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NIIHORI Tetsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. IMAI Kohsuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 青木洋子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Naruto Takuya 成戸 卓也

NARUTO Takuya 成戸 卓也

Research Projects

Research Products

Co-Researchers

パンゲノムの構築による希少疾患のゲノム構造異常に伴う遺伝子発現調節機構の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of biomarkers and elucidation of pathophysiology for coronary artery lesions of Kawasaki diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathological analysis of malignant rhabdoid tumor by utilizing the human disease model library

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the molecular mechanism and development of therapeutic method of exon skip caused by mutationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

CRLF2 over-expression analysis in precursor B-cell acute lymphoblastic leukemia in childrenPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genetic and genomic analysis on the patients with multiple congenital anomalies

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

TLR/Nod proteins in infants from dysregulation Pathological analysis Cytokine Storm

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarification of metabolic disorder and fever in hyper IgD syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of inflammatory cytokines on the differentiation of chondrogenic progenitor cells in the growth plates

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Exhaustive analysis about juvenile idiopathic arthritis by using an anti-IL-6 receptor antibody

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Update of the genotype and phenotype of KMT2D and KDM6A by genetic screening of 100 patients with clinically suspected Kabuki syndrome2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A deep intronic mutation of c.1166-285?T?>?G in SLC46A1 is shared by four unrelated Japanese patients with hereditary folate malabsorption (HFM)2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel UBE2A mutation causes X-linked intellectual disability type Nascimento.2017

Author(s)

Journal Title

Data Source

[Journal Article] Microdeletion of 19p13.3 in a girl with Peutz-Jeghers syndrome, intellectual disability, hypotonia, and distinctive features.2015

Naruto Takuya 成戸卓也

NARUTO Takuya 成戸卓也