IWAIZUMI Moriya 岩泉守哉

Researcher Number	60444361
Other IDs	https://orcid.org/0000-0002-2629-0830
Affiliation (Current)	2021: 浜松医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2013 – 2020: 浜松医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related Except Principal Investigator Gastroenterology / Basic Section 52010:General internal medicine-related / Basic Section 56060:Ophthalmology-related
Keywords	Principal Investigator マイクロサテライト不安定性 / 大腸がん / 大腸癌 / 薬物療法 / 感受性 / MBD4 / 5FU / TAS102 / FTD / 染色体不安定性 … More Except Principal Investigator 潰瘍性大腸炎 / 糞便 / 糞便RNA発現 / 糞便RNA検査 / 疾患活動性 / RNA / がん遺伝子パネル検査 / 外部精度評価 / EQA / 検査の質保証 / 次世代シークエンサー / 臨床検査の質保証 / 技能試験 / 難治性未診断眼疾患 / 希少眼疾患 / 遺伝子診断 Less

To improve quality of cancer gene panel tests by strategic implementation of external quality assessment scheme
- Principal Investigator
  
  前川真人
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Hamamatsu University School of Medicine
わが国の難治性未診断眼疾患に対する新しい疾患概念の確立と診断法の開発に関する研究
- Principal Investigator
  
  堀田喜裕
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Hamamatsu University School of Medicine
DNAミスマッチ修復正常型高頻度変異大腸がんのDNAポリメラーゼ校正機能解析Principal Investigator
- Principal Investigator
  
  岩泉守哉
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hamamatsu University School of Medicine
SGO1 mutation by MSI induces CINPrincipal Investigator
- Principal Investigator
  
  Iwaizumi Moriya
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Hamamatsu University School of Medicine
MBD4 mutation caused by MSI and 5FU chemosensitivity in colorectal cancerPrincipal Investigator
- Principal Investigator
  
  Iwaizumi Moriya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Hamamatsu University School of Medicine
Are fecal mRNA assay useful for ulcerative colitis ?
- Principal Investigator
  
  KANAOKA SHIGERU
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Hamamatsu University School of Medicine

All 2020 2019 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Microsatellite frameshift variants in SGO1 of gastric cancer are not always associated with MSI status.2020
- Author(s)
  http://orcid.org/0000-0001-5601-4741Tomohiro Sugiyama, Moriya Iwaizumi, Terumi Taniguchi, Satoshi Suzuki, Shinya Tani, Mihoko Yamade, Yasushi Hamaya, Satoshi Osawa, Takahisa Furuta, Hiroaki Miyajima, Tsutomu Ohta, Satoshi Baba, Haruhiko Sugimura, Masato Maekawa, Ken Sugimoto
- Journal Title
  
  Journal of Clinical Pathology
  
  Volume: 73 Pages: 206934-206934
- DOI
  10.1136/jclinpath-2020-206934
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08392, KAKENHI-PROJECT-20K07823, KAKENHI-PROJECT-18K07908
[Journal Article] Two independent families with strongly suspected hereditary diffuse gastric cancer based on the probands' endoscopic findings.2020
- Author(s)
  Iwaizumi M, Yamada H, Fukue M, Maruyama Y, Sonoda A, Sugimoto M, Koda K, Kushima R, Maekawa M, Sugimura H
- Journal Title
  
  Clin J Gastroenterol.
  
  Volume: 13 Pages: 754-758
- DOI
  10.1007/s12328-020-01163-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07823
[Journal Article] DNA mismatch repair is not disrupted in stage 0 colorectal cancer resected using endoscopic submucosal dissection.2020
- Author(s)
  Tomohiro Sugiyama, Moriya Iwaizumi, Masanao Kaneko, Shinya Tani, Mihoko Yamade, Yasushi Hamaya, Takahisa Furuta, Hiroaki Miyajima, Satoshi Osawa, Satoshi Baba, Masato Maekawa, Ken Sugimoto
- Journal Title
  
  Oncology letters
  
  Volume: 20(3) Pages: 2435-2441
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08392
[Journal Article] DNA mismatch repair is not disrupted in stage 0 colorectal cancer resected using endoscopic submucosal dissection2020
- Author(s)
  Sugiyama T, Iwaizumi M, Kaneko M, Tani S, Yamade M, Hamaya Y, Furuta T, Miyajima H, Osawa S, Baba S, Maekawa M, Sugimoto K
- Journal Title
  
  Oncology Letters
  
  Volume: 20 Pages: 2435-2441
- DOI
  10.3892/ol.2020.11799
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07823, KAKENHI-PROJECT-18K07908
[Journal Article] <i>MBD4</i> frameshift mutation caused by DNA mismatch repair deficiency enhances cytotoxicity by trifluridine, an active antitumor agent of TAS-102, in colorectal cancer cells2017
- Author(s)
  Suzuki Satoshi、Iwaizumi Moriya、Yamada Hidetaka、Sugiyama Tomohiro、Hamaya Yasushi、Furuta Takahisa、Kanaoka Shigeru、Sugimura Haruhiko、Miyajima Hiroaki、Osawa Satoshi、Carethers John M.、Sugimoto Ken
- Journal Title
  
  Oncotarget
  
  Volume: 9 Pages: 11477-11488
- DOI
  10.18632/oncotarget.22484
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09305
[Journal Article] 遺伝性腫瘍研究・腫瘍各論　家族性胃がん2016
- Author(s)
  岩泉守哉、椙村春彦
- Journal Title
  
  遺伝子医学MOOK　別冊（最新遺伝性腫瘍・家族性腫瘍研究と遺伝カウンセリング）
  
  Volume: 別冊 Pages: 202-206
- Data Source
  KAKENHI-PROJECT-16K09305
[Journal Article] Production of truncated MBD4 protein by frameshift mutation in DNA mismatch repair-deficient cells enhances 5-fluorouracil sensitivity that is independent of hMLH1 status.2016
- Author(s)
  Satoshi Suzuki, Ken Sugimoto, et al.
- Journal Title
  
  Cancer Biol Ther
  
  Volume: 17 Pages: 760-768
- DOI
  10.1080/15384047.2016.1178430
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460948, KAKENHI-PROJECT-16K09305
[Journal Article] A novel APC mosaicism in a patient with familial adenomatous polyposis2015
- Author(s)
  Moriya Iwaizumi, Ken Sugimoto, et al.
- Journal Title
  
  Hum Genome Variation
  
  Volume: 10 Pages: 15057-15057
- DOI
  10.1038/hgv.2015.57
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460948, KAKENHI-PROJECT-25860530, KAKENHI-PROJECT-26860206, KAKENHI-PROJECT-25280105
[Journal Article] 家族性胃癌2013
- Author(s)
  椙村春彦、山田英孝、陶　弘、新村和也、岩泉守哉、嵩　眞佐子
- Journal Title
  
  癌と化学療法
  
  Volume: 40 Pages: 154-158
- Data Source
  KAKENHI-PROJECT-25860530
[Journal Article] Acidic tumor microenvironment downregulates hMLH1 but does not diminish 5-fluorouracil chemosensitivity.2013
- Author(s)
  Iwaizumi M, Tseng-Rogenski S, Carethers JM
- Journal Title
  
  Mutat Res
  
  Volume: 747-748 Pages: 19-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860530
[Presentation] A frameshift mutation of SGO1 independent of MSI-H/dMMR has a potential of resistance for taxane in gastric cancer.2019
- Author(s)
  Tomohiro Sugiyama, Moriya Iwaizumi, Satoshi Suzuki, Ken Sugimoto, Masato Maekawa, Haruhiko Sugimura
- Organizer
  11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09305
[Presentation] FAP患者における胃癌の検討－遺伝的要因が胃癌診療で重要視される時代へ－2016
- Author(s)
  岩泉守哉、山田英孝、椙村春彦
- Organizer
  第24回日本消化器関連学会週間　(JDDW2016)
- Place of Presentation
  神戸
- Year and Date
  2016-11-03
- Data Source
  KAKENHI-PROJECT-16K09305
[Presentation] 孤発性家族性大腸腺腫症はAPC短縮変異により引き起こされやすい2016
- Author(s)
  岩泉守哉、陶弘、杉山智洋、濱屋寧、倉地清隆、古川洋一、前川真人、椙村春彦
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K09305
[Presentation] 「大腸がんのプライマリケア遺伝診療」のための家庭医療スタッフの関わり2016
- Author(s)
  岩泉守哉、鳴本敬一郎、福江美咲、倉地清隆、椙村春彦、前川真人、緒方勤、井上真知子
- Organizer
  第22回日本家族性腫瘍学会学術集会
- Place of Presentation
  松山
- Year and Date
  2016-06-03
- Data Source
  KAKENHI-PROJECT-16K09305
[Presentation] Trifluridine to enhance cytotoxicity by DNA mismatch repair deficiency and subsequent MBD4 frameshift mutation in colorectal cancer.2016
- Author(s)
  Satoshi Suzuki, Moriya Iwaizumi, Yasushi Hamaya, Kosuke Takagaki, Satoshi Osawa, Takahisa Furuta, Ken Sugimoto
- Organizer
  2016 Gastrointestinal Cancers Symposium (ASCO-GI 2016)
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2016-01-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860530
[Presentation] Fecal Hemoglobin as a Marker for Mucosal inflammation of Ulcerative Colitis : Usefulness of Combination with Rachmilewitz's Clinical Activity Index2014
- Author(s)
  Shigeru Kanaoka, Shigeru Kuriyama, Moriya Iwaizumi, Takanori Yamada, Mitsushige Sugimoto, Satoshi Osawa, Ken Sugimoto, Yoshisuke Hosoda, Yoshihiko Sato, Masami Yamada, Shigeto Yoshii, Kazuhiko Kawakami, Katsuhiko Nakai, Hiroaki Miyajima
- Organizer
  2014DDW
- Place of Presentation
  Chicago
- Year and Date
  2014-05-03
- Data Source
  KAKENHI-PROJECT-23590935
[Presentation] Potential Usefulness of Fecal Immunochemical Test plus Fecal microRNA Assay as a Marker for Colorectal Cancer Screening2013
- Author(s)
  Shigeru Kanaoka, Shigeru Kuriyama, Moriya Iwaizumi, Takanori Yamada, Mitsushige Sugimoto, Satoshi Osawa, Ken Sugimoto, Hiroaki Miyajima
- Organizer
  2013DDW
- Place of Presentation
  Orlando
- Year and Date
  2013-05-20
- Data Source
  KAKENHI-PROJECT-23590935
[Presentation] UCにおける粘膜治癒バイオマーカーとしての定量的便ヘモグロビン検査の有用性:CAIスコアや臨床検査値と比較して2013
- Author(s)
  金岡繁, 栗山茂, 岩泉守哉, 鈴木聡, 山田貴教, 杉本光繁, 大澤恵, 杉本健
- Organizer
  第55回日本消化器病学会大会(JDDW2013東京)
- Place of Presentation
  東京
- Year and Date
  2013-10-10
- Data Source
  KAKENHI-PROJECT-23590935
[Presentation] クローン病の臨床経過における喫煙の影響についての検討2013
- Author(s)
  杉本健, 岩泉守哉, 山田貴教, 杉本光繁, 金岡繁, 古田隆久, 大澤恵
- Organizer
  第55回日本消化器病学会大会(JDDW2013東京)
- Place of Presentation
  東京
- Year and Date
  2013-10-09
- Data Source
  KAKENHI-PROJECT-23590935
[Presentation] Fecal microRNA plus COX-2 mRNA Assays as a Marker for Colorectal Cancer Screening2013
- Author(s)
  Shigeru Kuriyama, Moriya Iwaizumi, Takanori Yamada, Mitsushige Sugimoto, Satoshi Osawa, Ken Sugimoto, Hiroaki Miyajima, Shigeru Kanaoka
- Organizer
  2013DDW
- Place of Presentation
  Orlando
- Year and Date
  2013-05-18
- Data Source
  KAKENHI-PROJECT-23590935
[Presentation] 腫瘍微小環境は大腸癌細胞のMLH1発現低下を誘導するが、5FUの耐性は誘導しない.
- Author(s)
  岩泉守哉、鈴木聡、椙村春彦、勝見章、大西一功
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25860530
[Presentation] MBD4 frameshift mutation changes 5-fluorouracil (5FU) sensitivity in colorectal cancer.
- Author(s)
  岩泉守哉、大澤恵、山田貴教、杉本光繁、古田隆久、金岡繁
- Organizer
  第11回日本臨床腫瘍学会学術集会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25860530
[Presentation] UCにおける粘膜治癒バイオマーカーとしての定量的便ヘモグロビン検査の有用性：CAIスコアや臨床検査値と比較して
- Author(s)
  金岡　繁、栗山　茂、岩泉守哉、鈴木　聡、山田貴教、杉本光繁、大澤　恵、杉本　健
- Organizer
  第55回日本消化器病学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590935
[Presentation] MBD4 Frameshift Mutation Enhances 5-Fluorouracil (5FU) Sensitivity in Colorectal Cancer.
- Author(s)
  Iwaizumi M, Martin P, Tseng-Rogenski S, Kanaoka S, Carethers JM
- Organizer
  2013 American Gastroenterological Association (AGA)/Digestive disease Week (DDW) annual meeting
- Place of Presentation
  Orlando, FL, USA
- Data Source
  KAKENHI-PROJECT-25860530
[Presentation] Fecal Hemoglobin as a Marker for Mucosal inflammation of Ulcerative Colitis: Usefulness of Combination with Rachmilewitz’s Clinical Activity Index
- Author(s)
  Kanaoka S, Kuriyama S, Iwaizumi M, Yamada T, Sugimoto M, Osawa S, Hosoda Y, Sato Y, Yoshii S, Sugimoto K, MIyajima H
- Organizer
  2014 DDW-USA
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-23590935
[Presentation] MBD4 frameshift mutation changes 5-fluorouracil (5FU) sensitivity in colorectal cancer.
- Author(s)
  Iwaizumi M, Shinmura K, Ikuma M, Sugimura H
- Organizer
  The 7th Japan and US Collaboration Conference in Gastroenterology
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25860530

1. KANAOKA SHIGERU (00252172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. KURIYAMA Shigeru (90596446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. SUGIMOTO Ken (20529507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
4. 濱屋寧 (20436968)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 華表友暁 (40416665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 前川真人 (20190291)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 西尾和人 (10208134)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 坂井和子 (20580559)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 谷重喜 (80217116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 中谷中 (80237304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 松下一之 (90344994)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 堀田喜裕 (90173608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YAMAGUCHI Kiyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. YAMAGUCHI Rui

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 大澤恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. 古川洋一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 井元清哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

IWAIZUMI Moriya 岩泉 守哉

Research Projects

Research Products

Co-Researchers

To improve quality of cancer gene panel tests by strategic implementation of external quality assessment scheme

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

わが国の難治性未診断眼疾患に対する新しい疾患概念の確立と診断法の開発に関する研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

DNAミスマッチ修復正常型高頻度変異大腸がんのDNAポリメラーゼ校正機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

SGO1 mutation by MSI induces CINPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MBD4 mutation caused by MSI and 5FU chemosensitivity in colorectal cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Are fecal mRNA assay useful for ulcerative colitis ?

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Microsatellite frameshift variants in SGO1 of gastric cancer are not always associated with MSI status.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Two independent families with strongly suspected hereditary diffuse gastric cancer based on the probands' endoscopic findings.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DNA mismatch repair is not disrupted in stage 0 colorectal cancer resected using endoscopic submucosal dissection.2020

Author(s)

Journal Title

Data Source

[Journal Article] DNA mismatch repair is not disrupted in stage 0 colorectal cancer resected using endoscopic submucosal dissection2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] <i>MBD4</i> frameshift mutation caused by DNA mismatch repair deficiency enhances cytotoxicity by trifluridine, an active antitumor agent of TAS-102, in colorectal cancer cells2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 遺伝性腫瘍研究・腫瘍各論 家族性胃がん2016

Author(s)

Journal Title

Data Source

[Journal Article] Production of truncated MBD4 protein by frameshift mutation in DNA mismatch repair-deficient cells enhances 5-fluorouracil sensitivity that is independent of hMLH1 status.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel APC mosaicism in a patient with familial adenomatous polyposis2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 家族性胃癌2013

Author(s)

IWAIZUMI Moriya 岩泉守哉

[Journal Article] 遺伝性腫瘍研究・腫瘍各論　家族性胃がん2016