MIYANO KEI 宮野佳

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Miyano Kei 宮野佳

MIYANO Kei 宮野佳

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Researcher Number	60444783
Other IDs
Affiliation (Current)	2025: 川崎医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2022 – 2024: 川崎医科大学, 医学部, 講師 2018 – 2019: 川崎医科大学, 医学部, 助教 2017: 九州大学, 医学研究院, 助教 2014 – 2015: 九州大学, 医学(系)研究科(研究院), 助教 2013: 九州大学, 医学(系)研究科(研究院), 研究員 … More 2012: 九州大学, 医学研究院, 特任助教 2011 – 2012: 九州大学, 医学(系)研究科(研究院), 特任助教 2008 – 2010: Kyushu University, 医学研究院, 学術研究員 2007: Kyushu University, 生体防御医学研究所, 研究員 Less
Review Section/Research Field	Principal Investigator General medical chemistry / Transformative Research Areas, Section (III) / Basic Section 49010:Pathological biochemistry-related
Keywords	Principal Investigator 活性酸素 / NADPHオキシダーゼ / Nox / 膜タンパク質 / ROS / NADPH oxidase / 細胞遊走 / Nox2 / 殺菌 / Nox2/gp91^<phox> … More / gp91^<phox> / ERAD / 血管新生 / 遊走 / p22phox / 慢性肉芽腫症 / redox / membrane protein / 糖鎖修飾 / レドックス / スーパーオキシド / 上皮細胞 / レドックスシグナル / p67^<phox> / Rac / 膜ダンパク質 / 蛋白質 / シグナル伝達 / 酵素 / gp91phox Less

Control of redox reactions initiated by the supersulfur molecule of the Nox enzyme subunit p22phoxPrincipal Investigator
- Principal Investigator
  
  宮野佳
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kawasaki Medical School
Mechanism of endothelial cell migration leading to angiogenesis by reactive oxygenase NOX4Principal Investigator
- Principal Investigator
  
  宮野佳
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kawasaki Medical School
The molecular mechanism for the generation of ROS through NoxPrincipal Investigator
- Principal Investigator
  
  Miyano Kei
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kawasaki Medical School
  Kyushu University
Mechanism for interaction between Nox2 and p22phox: two membrane integrated proteins of the phagocytic oxidasePrincipal Investigator
- Principal Investigator
  
  Miyano Kei
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyushu University
Mechanism for interaction between Nox2/gp91^<phox>and p22^<phox>: two membrane proteins of the phagocyte NADPH oxidasePrincipal Investigator
- Principal Investigator
 
 MIYANO Kei
- Project Period (FY)
 2011 – 2012
- Research Category
 
 Grant-in-Aid for Young Scientists (B)
- Research Field
 
 General medical chemistry
- Research Institution
 Kyushu University
Mechanism for interaction between gp91phox and p22phox : two membrane-integrated proteins of the phagocyte NADPH oxidasePrincipal Investigator
- Principal Investigator
  
  MIYANO Kei
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyushu University
Mechanism for interaction between gp91phox and p22phox : two membrane-integrated proteins of the phagocyte NADPH oxidasePrincipal Investigator
- Principal Investigator
  
  MIYANO Kei
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyushu University

[Book] 酸化ストレスの医学改訂第2版2014
- Author(s)
  住本英樹, 宮野佳
- Total Pages
  456
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-25460372
[Book] Front. Gastrointest.Res2011
- Author(s)
  Sumimoto H, Minakami R, Miyano K
- Publisher
  In free radical biology in digestive diseases(The Nox Family of NADPH oxidases that Deliberately Produce Reactive Oxygen Species)(S.Karger)
- Data Source
  KAKENHI-PROJECT-21790283
[Book] 活性酸素生成酵素Nox/Duoxの調節機構と酸化ストレス2008
- Author(s)
  住本英樹,前原優一,宮野佳
- Publisher
  診断と治療社,酸化ストレスの医学
- Data Source
  KAKENHI-PROJECT-19790214
[Journal Article] Characterization of missense mutations in the NADPH oxidase partner p22phox in the A22° subtype of chronic granulomatous disease2023
- Author(s)
 Kawai Chikage、Kajikawa Mizuho、Yamauchi Akira、Okamoto Shuichiro、Kuribayashi Futoshi、Miyano Kei
- Journal Title
 
 Microbiology and Immunology
 
 Volume: 67 Issue: 4 Pages: 194-200
- DOI
 10.1111/1348-0421.13051
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-22K06934
[Journal Article] Ca2+‐binding‐region‐dependent cell surface localization of <scp>NADPH</scp> oxidase Nox52023
- Author(s)
 Miyano Kei、Kajikawa Mizuho
- Journal Title
 
 FEBS Letters
 
 Volume: 597 Issue: 5 Pages: 702-713
- DOI
 10.1002/1873-3468.14577
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-22K06934
[Journal Article] Regulation of Derlin-1-mediated degradation of NADPH oxidase partner p22 by thiol modification2022
- Author(s)
  Miyano Kei、Okamoto Shuichiro、Kajikawa Mizuho、Kiyohara Takuya、Kawai Chikage、Yamauchi Akira、Kuribayashi Futoshi
- Journal Title
  
  Redox Biology
  
  Volume: 56 Pages: 102479-102479
- DOI
  10.1016/j.redox.2022.102479
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06934
[Journal Article] Importance of accessibility to the extracellular juxtamembrane stalk region of membrane protein for substrate recognition by viral ubiquitin ligase K52022
- Author(s)
  Kajikawa Mizuho、Hata Mizuki、Ishimura Maho、Imaizumi Nanae、Kimura Minako、Miyano Kei、Ose Toyoyuki、Asai Daisuke、Ishido Satoshi、Kanamoto Taisei
- Journal Title
  
  Biochemical Journal
  
  Volume: 479 Issue: 20 Pages: 2261-2278
- DOI
  10.1042/bcj20220288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06934, KAKENHI-PROJECT-20K12657, KAKENHI-PROJECT-21H02408
[Journal Article] Inhibition of pancreatic cancer-cell growth and metastasis in vivo by a pyrazole compound characterized as a cell-migration inhibitor by an in vitro chemotaxis assay2022
- Author(s)
  Okamoto Shuichiro、Miyano Kei、et al.
- Journal Title
  
  Biomedicine & Pharmacotherapy
  
  Volume: 155 Pages: 113733-113733
- DOI
  10.1016/j.biopha.2022.113733
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06934, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-22H04923
[Journal Article] Soluble Regulatory Proteins for Activation of NOX Family NADPH Oxidases.2019
- Author(s)
  Sumimoto H, Minakami R, Miyano K.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1982 Pages: 121-137
- DOI
  10.1007/978-1-4939-9424-3_8
- ISBN
  9781493994236, 9781493994243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08637
[Journal Article] Intramolecular interaction in LGN, an adaptor protein that regulates mitotic spindle orientation.2019
- Author(s)
  Takayanagi H, Hayase J, Kamakura S, Miyano K, Chishiki K, Yuzawa S, Sumimoto H.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 294 Issue: 51 Pages: 19655-19666
- DOI
  10.1074/jbc.ra119.011457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06934, KAKENHI-PROJECT-17K08637
[Journal Article] Differential cell surface recruitment of the superoxide-producing NADPH oxidases Nox1, Nox2 and Nox5: The role of the small GTPase Sar12018
- Author(s)
  Kiyohara Takuya、Miyano Kei、Kamakura Sachiko、Hayase Junya、Chishiki Kanako、Kohda Akira、Sumimoto Hideki
- Journal Title
  
  Genes to Cells
  
  Volume: 印刷中 Issue: 6 Pages: 480-493
- DOI
  10.1111/gtc.12590
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26111009, KAKENHI-PROJECT-15K08309, KAKENHI-PROJECT-16K21221, KAKENHI-PROJECT-17K08637, KAKENHI-PROJECT-18K06934, KAKENHI-PROJECT-18K15047
[Journal Article] 活性酸素によるチオール基の酸化と細胞調節2015
- Author(s)
  宮野佳, 住本英樹
- Journal Title
  
  細胞工学
  
  Volume: 34 Pages: 377-378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460372
[Journal Article] DOCK2 and DOCK5 Act Additively in Neutrophils To Regulate Chemotaxis, Superoxide Production, and Extracellular Trap Formation.2014
- Author(s)
  Mayuki Watanabe, Masao Terasawa, Kei Miyano, Toyoshi Yanagihara, Takehito Uruno, Fumiyuki Sanematsu, Akihiko Nishikimi, Jean-Francois Cote, Hideki Sumimoto, Yoshinori Fukui
- Journal Title
  
  The Journal of Immunology
  
  Volume: 193 Pages: 5660-5667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460372
[Journal Article] N-Linked glycosylation of the superoxide-producing NADPH oxidase Nox1.2014
- Author(s)
  Miyano K, Sumimoto H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 443 Issue: 3 Pages: 1060-1065
- DOI
  10.1016/j.bbrc.2013.12.086
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460372, KAKENHI-PLANNED-26111009
[Journal Article] Visualization of phagosomal hydrogen peroxide production by a novel fluorescent probe that is localized via SNAP-tag labeling.2014
- Author(s)
  Masahiro Abo, Reiko Minakami, Kei Miyano, Mako Kamiya, Tetsuo Nagano, Yasuteru Urano, Hideki Sumimoto
- Journal Title
  
  Analytical chemistry
  
  Volume: 86 Pages: 5983-5990
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460372
[Journal Article] Arachidonic Acid Induces Direct Interaction of the p67phox-Rac Complex with the Phagocyte Oxidase Nox2, Leading to Superoxide Production.2014
- Author(s)
  Rumi Matono, Kei Miyano, Takuya Kiyohara, Hideki Sumimoto
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 289 Pages: 24874-24884
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460372
[Journal Article] Noxによる活性酸素産生機構2013
- Author(s)
  宮野佳, 住本英樹
- Journal Title
  
  医学のあゆみ
  
  Volume: 247 Pages: 739-745
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460372
[Journal Article] Assessment of the role for Rho family GTPases in NADPHoxidase activation2012
- Author(s)
  Miyano K, Sumimoto H
- Journal Title
  
  Methods Mol. Biol
  
  Volume: 827 Pages: 195-212
- DOI
  10.1007/978-1-61779-442-1_14
- ISBN
  9781617794414, 9781617794421
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117002, KAKENHI-PROJECT-21390084, KAKENHI-PROJECT-23790338
[Journal Article] Atypical membrane-embedded p47^<phox> PI(3,4)P_2 binding site on PX domain revealed by NMR2012
- Author(s)
 Stampoulis P, Ueda T, Matsumoto M, Terasawa H, Miyano K, Sumimoto H, and Shimada I
- Journal Title
 
 J. Biol. Chem
 
 Volume: 287 Issue: 21 Pages: 17848-17859
- DOI
 10.1074/jbc.m111.332874
- Peer Reviewed
- Data Source
 KAKENHI-PLANNED-20117002, KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-21390084, KAKENHI-PROJECT-23790042, KAKENHI-PROJECT-23790338, KAKENHI-ORGANIZER-21121001
[Journal Article] Blockade of inflammatory responses by a small-molecule inhibitor of the Rac activatorDOCK22012
- Author(s)
  Nishikimi A, Uruno T, Duan X, Cao Q, Okamura Y, Saitoh T, Saitoh N, Sakaoka S, Du Y, Suenaga A, Kukimoto-Niino M, Miyano K, Gotoh K, Okabe T, Sanematsu F, Tanaka Y, Sumimoto H., Honma T, Yokoyama S, Nagano T, Kohda D, Kanai M, and Fukui Y
- Journal Title
  
  Chem. Biol
  
  Volume: 19 Issue: 4 Pages: 488-497
- DOI
  10.1016/j.chembiol.2012.03.008
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117002, KAKENHI-PROJECT-22247017, KAKENHI-PUBLICLY-23111522, KAKENHI-PROJECT-23790338, KAKENHI-PROJECT-24590586, KAKENHI-PROJECT-24770127, KAKENHI-ORGANIZER-24111001
[Journal Article] Sumimoto H Assessment of the role for Rho family GTPase in NADPH oxidase activation Methods2011
- Author(s)
  Miyano K
- Journal Title
  
  Mol.Biol. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790283
[Journal Article] Selectively induced apoptosis in human neutrophils in the presence of oxidative phenoxazines, 2-amino-4, 4α-dihydryo-4α-7H-phenoxazine-3-one and 2-aminophenoxazine-3-one preceded by decrease of intracellular pH, depolarization of the mitochondria and inhibition of superoxide generation.2011
- Author(s)
  Tabuchi T., Che X.-F., Hiraishi K., Adachi M., Miyano K., Sumimoto H., Tabuchi T.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 117 Pages: 139-148
- NAID
  10030453178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790338
[Journal Article] Assessment of the Role for Rho family GTPases in NADPH oxidase activation2011
- Author(s)
  Kei Miyano, et al.
- Journal Title
  
  Methods Mol.Biol.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790283
[Journal Article] Selectively induced apoptosis in human neutrophils in the presence of oxidative phenoxazines, 2-amino-4, 4α-dihydryo-4α-7H-phenoxazine-3-one and 2-aminophenoxazine-3-one preceded by decrease of intracellular pH, depolarization of the mitocho2011
- Author(s)
  Tabuchi T., Che X.-F.,Hiraishi K., Adachi M., Miyano K., Sumimoto H., Tabuchi T., Miyazawa K., and Tomoda A
- Journal Title
  
  J. Pharmacol. Sci
  
  Volume: 117 Pages: 139-48
- URL
  https://www.jstage.jst.go.jp/article/jphs/117/3/117_11134FP/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790338
[Journal Article] A conserved region between the TPR and activation domains of p67^phox participates in activation of the phagocyte NADPH oxidase2010
- Author(s)
  Maehara Y, Miyano K, Yuzawa S, Akimoto R, Takeya R, Sumimoto H
- Journal Title
  
  J Biol Chem. 285
  
  Pages: 31435-31445
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790283
[Journal Article] Membrane phospholipid metabolism during phagocytosis in human neutrophils2010
- Author(s)
  Minakami R, Maehara Y, Kamakura S, Kumano O, Miyano K, Sumimoto H
- Journal Title
  
  Genes Cells. 15
  
  Pages: 409-424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790283
[Journal Article] The insert region of the Rac GTPases is dispensable for activation of superoxide-producing NADPH oxidases.2009
- Author(s)
  Miyano K, Koga H, Minakami R, Sumimoto H
- Journal Title
  
  Biochem J. 422
  
  Pages: 373-382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790283
[Journal Article] Role for the first SH3 domain of p67phox in activation of superoxide-producing NADPH oxidases2009
- Author(s)
  Yuichi Maehara, Kei Miyano, Hideki Sumimoto
- Journal Title
  
  Biochemical and biophysical research communications 379
  
  Pages: 589-593
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790214
[Journal Article] The domain organization of p67^phox, a protein required for activation of the superoxide-producing NADPH oxidase in phagocytes.2009
- Author(s)
  Yuzawa S, Miyano K, Honbou K, Inagaki F, Sumimoto H
- Journal Title
  
  J Innate Immun. 1
  
  Pages: 543-555
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790283
[Journal Article] A region N-terminal to the tandem SH3 domain of p47phox plays a crucial role in activation of the phagocyte NADPH oxidase2009
- Author(s)
  Masahiko Taura, Kei Miyano, Reiko Minakami, Sachiko Kamakura, Ryu Takeya, Hideki Sumimoto
- Journal Title
  
  The Biochemical journal 419
  
  Pages: 329-338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790214
[Journal Article] 酸化ストレス応答とNoxファミリー2009
- Author(s)
  宮野佳, 住本英樹
- Journal Title
  
  生物資料分析 32
  
  Pages: 289-296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790283
[Journal Article] 酸化ストレス応答とNoxファミリー2009
- Author(s)
  宮野佳, 他
- Journal Title
  
  生物試料分析 32
  
  Pages: 289-296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790283
[Journal Article] The insert region of the Rac GTPases is dispensable for activation of superoxide-producing NADPH oxidases2009
- Author(s)
  Kei Miyano, et al.
- Journal Title
  
  Biochemical Journal 422
  
  Pages: 373-382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790283
[Journal Article] 好中球による活性酸素産生の分子機構2008
- Author(s)
  宮野佳,住本英樹
- Journal Title
  
  感染炎症免疫 38
  
  Pages: 14-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790214
[Journal Article] Noxファミリーメンバーの活性調節機構2008
- Author(s)
  前原優一,宮野佳,住本英樹
- Journal Title
  
  Journal of Gastrointestinal Research 16
  
  Pages: 3-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790214
[Journal Article] 好中球による活性酸素産生の分子機構2008
- Author(s)
  宮野佳, 他
- Journal Title
  
  感染炎症免疫 38
  
  Pages: 14-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790214
[Journal Article] p40phox as an alternative organizer to p47phox in Nox2 activation : A new mechanism involving an interaction with p22phox2007
- Author(s)
  Minoru Tamura, Ichiro Shiozaki, Shohei Ono, Kei Miyano, Sachio Kunihiro, Takayuki Sas
- Journal Title
  
  FEBS Letters 581
  
  Pages: 4533-4538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790214
[Journal Article] Role of the small GTPase Rac in p22^<phox->dependent NADPH oxidases2007
- Author(s)
 Kei, Miyano, et. al.
- Journal Title
 
 Biochimie 89
 
 Pages: 1133-1144
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-19790214
[Journal Article] Role of the small GTPase Rac in p22phox-dependent NADPH oxidases2007
- Author(s)
  Kei Miyano, Hideki Sumimoto
- Journal Title
  
  Biochimie 89
  
  Pages: 1133-1144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790214
[Journal Article] Noxファミリーの調節機構2007
- Author(s)
  宮野佳, et. al.
- Journal Title
  
  臨床検査 51
  
  Pages: 1111-1115
- Data Source
  KAKENHI-PROJECT-19790214
[Journal Article] Noxファミリーの調節機構2007
- Author(s)
  宮野佳,水上令子,住本英樹
- Journal Title
  
  臨床検査 51
  
  Pages: 1111-1115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790214
[Presentation] 活性酸素生成酵素NADPHオキシダーゼのタンパク質安定化機構の解明2023
- Author(s)
  宮野佳, 梶川瑞穂
- Organizer
  第46回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K06934
[Presentation] Polysulfide donor can enhance the bacteria killing capability of macrophage and neutrophil.2023
- Author(s)
  Rahman Azizur、張田力、津々木博康、宮野佳、山内明、赤池孝章、澤智裕
- Organizer
  第76回日本酸化ストレス学会学術集会
- Data Source
  KAKENHI-PROJECT-22K06934
[Presentation] 食細胞NADPHオキシダーゼのサブユニットp22phoxのミスセンス変異は、タンパク質安定性とNox2結合能を減弱し、慢性肉芽腫症を引き起こす2023
- Author(s)
  宮野佳、川井千景、梶川瑞穂、山内明、岡本秀一郎、栗林太
- Organizer
  第34回　日本生体防御学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06934
[Presentation] 活性酸素生成酵素NADPHオキシダーゼのパートナー分子p22phoxの分解制御機構の解明2023
- Author(s)
  宮野佳, 岡本秀一郎, 梶川瑞穂, 清原卓也, 川井千景, 山内明, 栗林太
- Organizer
  第76回日本酸化ストレス学会学術集会
- Data Source
  KAKENHI-PROJECT-22K06934
[Presentation] 小胞体関連分解因子による生体レドックス反応の制御機構の解明2023
- Author(s)
  宮野佳、岡本秀一郎、山内明、栗林太
- Organizer
  第64回日本生化学会中国四国支部例会
- Data Source
  KAKENHI-PROJECT-22K06934
[Presentation] モノクローナル抗体CL-5および48のヒトgp91phox/Nox2上のエピトープ探索2022
- Author(s)
  川井千景, 岡本秀一郎, 梶川瑞穂, 山内明, 栗林太, 宮野佳
- Organizer
  第33回日本生体防御学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06934
[Presentation] Down-regulation of ROS-generating NADPH oxidase 4 (NOX4) expression in hemangioendothelioma．2022
- Author(s)
  宮野佳
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K06934
[Presentation] 高尿酸状態の免疫細胞機能への影響　～尿酸に善玉作用はあるのか～2020
- Author(s)
  山内明、岡本秀一郎、宮野佳、板谷益美、川井千景、栗林太
- Organizer
  第53回日本痛風・尿酸核酸学会
- Data Source
  KAKENHI-PROJECT-17K08637
[Presentation] 高尿酸血症の免疫機能への影響：尿酸は敵か味方か？2019
- Author(s)
  山内明、岡本秀一郎、宮野佳、板谷益美、川井千景、栗林太
- Organizer
  第92回生化学会
- Data Source
  KAKENHI-PROJECT-17K08637
[Presentation] 活性酸素生成型NADPHオキシダーゼ1（Nox1）の細胞膜輸送と活性化におけるパートナー分子p22phoxの役割2015
- Author(s)
  宮野佳, 住本英樹
- Organizer
  第26回　日本生体防御学会学術総会
- Place of Presentation
  浅草
- Year and Date
  2015-07-10
- Data Source
  KAKENHI-PROJECT-25460372
[Presentation] 活性酸素生成型NADPH oxidaseの進化と動物における調節機構2015
- Author(s)
  住本英樹, 宮野佳
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-25460372
[Presentation] Role for a conserved region of the superoxide-producing NADPH oxidase 5 (Nox5)2013
- Author(s)
  Kei Miyano, Hideki Sumimoto
- Organizer
  第36回　日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25460372
[Presentation] 細胞刺激に応じた活性酸素生成型NADPHオキシダーゼ5（Nox5）の活性化におけるN末端細胞質領域の役割2013
- Author(s)
  宮野佳、住本英樹
- Organizer
  第86回　日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25460372
[Presentation] 活性酸素生成酵素NADPHオキシダーゼ5（Nox5）の活性化におけるN末端領域の役割2013
- Author(s)
  宮野佳、住本英樹
- Organizer
  第24回日本生体防御学会学術総会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25460372
[Presentation] Nox family NAPDH oxidases and redox signaling.2012
- Author(s)
  Hideki Sumimoto, Kei Miyano
- Organizer
  第85回日本生化学会大会:シンポジウム「Frontiers in redox signaling and oxidative stress research 」
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23790338
[Presentation] アラキドン酸は、p47^<phox>の構造変化に加えてp67^<phox>-Nox2間の相互作用を誘導することにより食細胞NADPHオキシダーゼを活性化する. Arachidonic acid induces not only a conformational change of p47^<phox>but also interaction of p67^<phox>with Nox2 to activate the phagocyte NADPH oxidase.2012
- Author(s)
 的野る美, 宮野佳, 住本英樹.
- Organizer
 第85回日本生化学会大会
- Place of Presentation
 福岡
- Data Source
 KAKENHI-PROJECT-23790338
[Presentation] スーパーオキシド生成酵素NADPHオキシダーゼ5(Nox5)の細胞膜への局在化と酵素活性化に必要なN末端細胞質領域の同定.A region N-terminal to the transmembrane domain of NADPH oxidase5 (Nox5) is required for the plasma membrane localization of Nox5 and the oxidase activation.2012
- Author(s)
  宮野佳, 住本英樹
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23790338
[Presentation] 活性酸素シグナル生成の制御と遺伝学2012
- Author(s)
  住本英樹,宮野佳
- Organizer
  日本遺伝学会第84回大会:公開シンポジウム「活性酸素シグナル伝達制御の遺伝学」
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23790338
[Presentation] スーパーオキシド生成酵素NADPHオキシダーゼ5（Nox5）の細胞膜への局在化と酵素活性化に必要なN末端細胞質領域の同定2012
- Author(s)
  宮野佳 et. al.
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23790338
[Presentation] Structure and regulation of Nox family NADPH oxidases that deliberately produce reactive oxygen species [invited speaker]2011
- Author(s)
  Sumimoto, H., and Miyano
- Organizer
  The 17th International Symposium on Flavins and Flavoproteins.
- Place of Presentation
  Berkeley, USA
- Data Source
  KAKENHI-PROJECT-23790338
[Presentation] The Nox family NADPH oxidases involved in host defense and signal transduction [invited speaker]2011
- Author(s)
  Sumimoto, H., and Miyano, K.
- Organizer
  The 13th International Congress of Bacteriology and Applied Microbiology: Symposium "ROS signaling in host-bacteria stress responses"
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-23790338
[Presentation] 活性酸素生成酵素NADPHオキシダーゼの活性調節領域について2011
- Author(s)
  宮野佳, 住本英樹
- Organizer
  2011年度日本生化学会九州支部例会
- Place of Presentation
  久留米
- Data Source
  KAKENHI-PROJECT-23790338
[Presentation] 食細胞と非食細胞NADPHオキシダーゼの活性酸素生成活性の制御領域について2011
- Author(s)
  宮野佳、住本英樹
- Organizer
  生体防御学会
- Place of Presentation
  那覇
- Data Source
  KAKENHI-PROJECT-23790338
[Presentation] 食細胞と非食細胞NADPHオキシダーゼの活性酸素生成活性の制御領域について2011
- Author(s)
  宮野佳,住本英樹
- Organizer
  第22回日本生体防御学会学術総会
- Place of Presentation
  那覇
- Data Source
  KAKENHI-PROJECT-23790338
[Presentation] 活性酸素生成型NADPHオキシダーゼ(Nox)ファミリーの活性化における膜貫通領域と細胞質領域の役割2010
- Author(s)
  宮野佳, 住本英樹
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21790283
[Presentation] Roles for the N-terminal transmembrane and C-terminal cytosolic moieties of Nox-family NADPH oxidases2010
- Author(s)
  Miyano K, Sumimoto H
- Organizer
  Gordon Research Conference(Nox family NADPH oxidases)
- Place of Presentation
  Les Diablerets, the Switzerland
- Data Source
  KAKENHI-PROJECT-21790283
[Presentation] Roles for the N-terminal transmembrane and C-terminal cytosolic moieties of Nox-family NADPH oxidases2010
- Author(s)
  Kei Miyano, et al.
- Organizer
  Gordon Research Conference (Nox Family NADPH Oxidases)
- Place of Presentation
  Les Diablerets, the Switzerland
- Data Source
  KAKENHI-PROJECT-21790283
[Presentation] 生体防御に重要な活性酸素生成酵素NADPHオキシダーゼの活性化機構2010
- Author(s)
  宮野佳, 住本英樹
- Organizer
  第21回日本生体防御学会学術総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21790283
[Presentation] スーパーオキシド生成酵素NADPHオキシダーゼの活性化因子p67^phoxの作用機構の解明2009
- Author(s)
  宮野佳, 前原優一, 湯澤聡, 住本英樹
- Organizer
  平成21年度日本生化学会九州支部例会
- Data Source
  KAKENHI-PROJECT-21790283
[Presentation] The domain organization of p67^phox, a protein required for activation of the superoxide-producing NADPH oxidase in phagocytes2009
- Author(s)
  湯澤聡, 宮野佳, 本坊和也, 稲垣冬彦, 住本英樹
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21790283
[Presentation] Rac-dependent activation of superoxide-producing NADPH oxidases does not require its insert region2009
- Author(s)
  宮野佳, 古賀博文, 水上令子, 住本英樹
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21790283
[Presentation] Racのinsert regionは活性酸素生成酵素NAPDHオキシダーゼ活性化に必要ない2009
- Author(s)
  宮野佳, 古賀博文, 水上令子, 住本英樹
- Organizer
  第82回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21790283
[Presentation] Rac-dependent activation of superoxide-producing NADPH oxidases doesnot require its insert region2009
- Author(s)
  宮野佳, 他
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21790283
[Presentation] スーパーオキシド生成酵素NADPHオキシダーゼの活性化因子p67phoxの作用機構の解明2009
- Author(s)
  宮野佳, 他
- Organizer
  平成21年度日本生化学会九州支部例会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-21790283
[Presentation] Nox2活性化におけるp67^phoxのドメイン配置と作用機構2009
- Author(s)
  湯澤聡, 宮野佳, 本坊和也, 稲垣冬彦, 住本英樹
- Organizer
  第82回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21790283
[Presentation] 低分子量Gタンパク質Racのinsert regionは活性酸素生成酵素NAPDHオキシダーゼ活性化に必要ない2009
- Author(s)
  宮野佳, 他
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21790283
[Presentation] 低分子量Gタンパク質による活性酸素生成型NADPHオキシダーゼの調節機構2008
- Author(s)
  住本英樹,宮野佳,武谷立,水上令子
- Organizer
  第30回薬学会九州支部コロキウム「生命機能をつかさどるG蛋白質シグナリング」
- Place of Presentation
  福岡
- Year and Date
  2008-10-25
- Data Source
  KAKENHI-PROJECT-19790214
[Presentation] スーパーオキシド生成酵素Nox1-Nox3の活性化における低分子量Gタンパク質Racの役割2008
- Author(s)
  宮野佳,住本英樹
- Organizer
  第18回日本生体防学会学術総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19790214
[Presentation] 食細胞NADPHオキシダーゼgp91phox/Nox2と非食細胞Nox1とNox3の活性化における低分子量Gタンパク質Racのinsert helixの役割2008
- Author(s)
  宮野佳,住本英樹
- Organizer
  第19回日本生体防御学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19790214
[Presentation] 活性酸素生成酵素NADPHオキシダーゼの活性化におけるRac のinsert helix の役割2008
- Author(s)
  宮野佳,住本英樹
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19790214
[Presentation] 活性酸素生成酵素NADPHオキシダーゼの活性化におけるRacのinsert helixの役割2008
- Author(s)
  宮野佳, 他
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19790214
[Presentation] 活性酸素生成型NADPHオキシダーゼの活性化の分子機構2008
- Author(s)
  住本英樹,宮野佳,水上令子
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19790214
[Presentation] 食細胞NADPHオキシダーゼgp91^<phox>/Nox2と非食細胞Nox1とNok3の活性化における低分子量Gタンパク質Racのinsert helixの役割2008
- Author(s)
 宮野佳, 他
- Organizer
 第19回日本生体防御学会学術総会
- Place of Presentation
 札幌
- Data Source
 KAKENHI-PROJECT-19790214
[Presentation] p67phoxによる活性酸素生成酵素Nox2の活性化機構2008
- Author(s)
  前原優一,宮野佳,住本英樹
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19790214
[Presentation] スーパーオキシド生成型NADPHオキシダーゼNox1-Nox3の活性化における低分子量Gタンパク質Racの役割2007
- Author(s)
  宮野佳, et. al.
- Organizer
  第30回本分子物学会, 第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19790214
[Presentation] スーパーオキーシド生成酵素Nox1-Nox3の活性化における低分子量Gタンパク質Racの役割2007
- Author(s)
  宮野佳, et. al.
- Organizer
  第18回日本生体防学会学術総会
- Place of Presentation
  福岡
- Year and Date
  2007-07-26
- Data Source
  KAKENHI-PROJECT-19790214
[Presentation] スーパーオキシド生成型NADPHオキシダーゼNox1-Nox3の活性化における低分子量Gタンパク質Racの役割2007
- Author(s)
  宮野佳,住本英樹
- Organizer
  第30回日本分子生物学会年会第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19790214
[Presentation] スーパーオキシド生成酵素NADPHオキシダーゼ1（Nox1）のN結合型糖鎖修飾
- Author(s)
  宮野佳, 住本英樹
- Organizer
  日本生化学会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25460372

1. 住本英樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
2. 鎌倉幸子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MIYANO KEI 宮野 佳

Miyano Kei 宮野 佳

MIYANO Kei 宮野 佳

Research Projects

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Co-Researchers

Control of redox reactions initiated by the supersulfur molecule of the Nox enzyme subunit p22phoxPrincipal Investigator

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Mechanism of endothelial cell migration leading to angiogenesis by reactive oxygenase NOX4Principal Investigator

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The molecular mechanism for the generation of ROS through NoxPrincipal Investigator

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Mechanism for interaction between Nox2 and p22phox: two membrane integrated proteins of the phagocytic oxidasePrincipal Investigator

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Mechanism for interaction between Nox2/gp91^<phox>and p22^<phox>: two membrane proteins of the phagocyte NADPH oxidasePrincipal Investigator

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Mechanism for interaction between gp91phox and p22phox : two membrane-integrated proteins of the phagocyte NADPH oxidasePrincipal Investigator

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Mechanism for interaction between gp91phox and p22phox : two membrane-integrated proteins of the phagocyte NADPH oxidasePrincipal Investigator

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[Book] 酸化ストレスの医学 改訂第2版2014

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[Book] Front. Gastrointest.Res2011

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[Book] 活性酸素生成酵素Nox/Duoxの調節機構と酸化ストレス2008

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[Journal Article] Characterization of missense mutations in the NADPH oxidase partner p22<sup><i>phox</i></sup> in the A22° subtype of chronic granulomatous disease2023

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[Journal Article] Ca<sup>2+</sup>‐binding‐region‐dependent cell surface localization of <scp>NADPH</scp> oxidase Nox52023

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[Journal Article] Regulation of Derlin-1-mediated degradation of NADPH oxidase partner p22 by thiol modification2022

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[Journal Article] Importance of accessibility to the extracellular juxtamembrane stalk region of membrane protein for substrate recognition by viral ubiquitin ligase K52022

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MIYANO KEI 宮野佳

Miyano Kei 宮野佳

MIYANO Kei 宮野佳

[Book] 酸化ストレスの医学改訂第2版2014