Hayashi Kaori 林香

… Alternative Names

HAYASHI Kaori 林香

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Researcher Number	60445294
Affiliation (Current)	2025: 慶應義塾大学, 医学部(信濃町), 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 慶應義塾大学, 医学部(信濃町), 教授 2021 – 2022: 慶應義塾大学, 医学部(信濃町), 講師 2018 – 2020: 慶應義塾大学, 医学部(信濃町), 助教 2017: 慶應義塾大学, 医学部, 助教 2016: 慶應義塾大学, 医学部(信濃町), 助教 2011 – 2015: 慶應義塾大学, 医学部, 助教 2008: 慶應義塾大学, 医学部, 研究員(非常勤)
Review Section/Research Field	Principal Investigator Kidney internal medicine / Basic Section 53040:Nephrology-related / Medium-sized Section 52:General internal medicine and related fields Except Principal Investigator Basic Section 53040:Nephrology-related / Medium-sized Section 53:Organ-based internal medicine and related fields / Kidney internal medicine
Keywords	Principal Investigator 慢性腎臓病 / エピゲノム / ポドサイト / DNA損傷修復 / DNAメチル化 / DNA損傷 / エピゲノム変化 / 蛋白尿 / KLF4 / 血球 … More / 尿サンプル / 尿中赤血球 / Deep learning / AI / 血尿 / 腎老化 / 老化 / エピジェネティクス / KAT5 / 糖尿病性腎症 / エピジェネティックス / エピジェネテイック / 尿蛋白 / ネフリン / 糸球体上皮細胞(ポドサイト) / 糸球体上皮細胞 / 高血圧 / 腎臓 … More Except Principal Investigator DNA損傷修復 / 慢性腎臓病 / 臓器連関 / エピゲノム変化 / 代謝腎臓病 / NAD代謝 / ニコチン酸代謝 / DNA損傷 / エピゲノム / 腎臓病 / 高血圧 Less

腎臓におけるDNA損傷修復と全身代謝変容連関の解明
- Principal Investigator
  
  菱川彰人
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Keio University
尿中細胞の深層学習・画像解析による腎疾患早期診断方法の開発Principal Investigator
- Principal Investigator
  
  林香
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Keio University
血球細胞DNAメチル化をターゲットとした慢性腎臓病新規治療戦略の開発Principal Investigator
- Principal Investigator
  
  林香
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Keio University
Spiral progression of DNA damage repair, epigenetic alterations and metabolic changes in metabolic kidney diseases
- Principal Investigator
  
  ITOH Hiroshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Keio University
Association of podocyte DNA damage and epigenetic alterations with renal agingPrincipal Investigator
- Principal Investigator
  
  Hayashi Kaori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Keio University
Epigenetic regulation through angiotensin blockade in podocytesPrincipal Investigator
- Principal Investigator
  
  Hayashi Kaori
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University
Epigenetic regulation of podocyte phenotype through KLF4Principal Investigator
- Principal Investigator
  
  Hayashi Kaori
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University
The role of Kruppel-like Factor 4 (KLF4)in glomerular podocytes and its application to the therapy of proteinuria.Principal Investigator
- Principal Investigator
  
  HAYASHI Kaori
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University
Transient treatment with ARB can suppress the development of hypertension and nephropathy
- Principal Investigator
  
  ISHIGURO Kimiko
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University

[Journal Article] Podocyte Ercc1 is indispensable for glomerular integrity2024
- Author(s)
  Hama Eriko Yoshida、Nakamichi Ran、Hishikawa Akihito、Kihara Miho、Abe Takaya、Yoshimoto Norifumi、Nishimura Erina Sugita、Itoh Hiroshi、Hayashi Kaori
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 704 Pages: 149713-149713
- DOI
  10.1016/j.bbrc.2024.149713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K18270, KAKENHI-PROJECT-22K19511, KAKENHI-PROJECT-23K24351
[Journal Article] Significance of podocyte DNA damage and glomerular DNA methylation in CKD patients with proteinuria2023
- Author(s)
  Yoshimoto Norifumi、Hayashi Kaori、Hishikawa Akihito、Hashiguchi Akinori、Nakamichi Ran、Sugita-Nishimura Erina、Yoshida-Hama Eriko、Azegami Tatsuhiko、Nakayama Takashin、Itoh Hiroshi
- Journal Title
  
  Hypertension Research
  
  Volume: 46 Issue: 4 Pages: 1000-1008
- DOI
  10.1038/s41440-023-01169-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00535, KAKENHI-PROJECT-22K19511, KAKENHI-PROJECT-23K24351
[Journal Article] DNA-damaged podocyte-CD8 T cell crosstalk exacerbates kidney injury by altering DNA methylation2023
- Author(s)
  Nakamichi Ran、Hishikawa Akihito、Chikuma Shunsuke、Yoshimura Akihiko、Sasaki Takashi、Hashiguchi Akinori、Abe Takaya、Tokuhara Tomoko、Yoshimoto Norifumi、Nishimura Erina Sugita、Hama Eriko Yoshida、Azegami Tatsuhiko、Nakayama Takashin、Hayashi Kaori、Itoh Hiroshi
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 5 Pages: 112427-112427
- DOI
  10.1016/j.celrep.2023.112427
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00535
[Journal Article] Plasminogen activator inhibitor 1 is not a major causative factor for exacerbation in a mouse model of SARS-CoV-2 infection2023
- Author(s)
  Nakayama Takashin、Azegami Tatsuhiko、Kiso Maki、Imai Masaki、Uraki Ryuta、Hayashi Kaori、Hishikawa Akihito、Yoshimoto Norifumi、Nakamichi Ran、Sugita-Nishimura Erina、Yoshida-Hama Eriko、Kawaoka Yoshihiro、Itoh Hiroshi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 3103-3103
- DOI
  10.1038/s41598-023-30305-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19511, KAKENHI-PROJECT-20H00535, KAKENHI-PROJECT-21K18270
[Journal Article] DNA-damaged podocyte-CD8 T?cell crosstalk exacerbates kidney injury by altering DNA methylation2023
- Author(s)
  Nakamichi Ran、Hishikawa Akihito、Chikuma Shunsuke、Yoshimura Akihiko、Sasaki Takashi、Hashiguchi Akinori、Abe Takaya、Tokuhara Tomoko、Yoshimoto Norifumi、Nishimura Erina Sugita、Hama Eriko Yoshida、Azegami Tatsuhiko、Nakayama Takashin、Hayashi Kaori、Itoh Hiroshi
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 4 Pages: 112302-112302
- DOI
  10.1016/j.celrep.2023.112302
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18270, KAKENHI-PROJECT-22K19444, KAKENHI-PROJECT-22K19446, KAKENHI-PROJECT-21H05044, KAKENHI-PROJECT-23K24114, KAKENHI-PROJECT-22K19511, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-23K24351
[Journal Article] Correction: Mechanisms of mineralocorticoid receptor-associated hypertension in diabetes mellitus: the role of O-GlcNAc modification2023
- Author(s)
  Jo Rie、Shibata Hirotaka、Kurihara Isao、Yokota Kenichi、Kobayashi Sakiko、Murai-Takeda Ayano、Mitsuishi Yuko、Hayashi Takeshi、Nakamura Toshifumi、Itoh Hiroshi
- Journal Title
  
  Hypertension Research
  
  Volume: 46 Issue: 3 Pages: 814-814
- DOI
  10.1038/s41440-023-01167-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00535
[Journal Article] Targeting DNA Methylation in Podocytes to Overcome Chronic Kidney Disease2023
- Author(s)
  Hayashi Kaori
- Journal Title
  
  The Keio Journal of Medicine
  
  Volume: 72 Issue: 3 Pages: 67-76
- DOI
  10.2302/kjm.2022-0017-IR
- ISSN
  0022-9717, 1880-1293
- Language
  English
- Data Source
  KAKENHI-PROJECT-22K19511, KAKENHI-PROJECT-23K24351
[Journal Article] Altered DNA methylation in kidney disease: Useful markers and therapeutic targets.2022
- Author(s)
  Kaori Hayashi
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 26(4) Issue: 4 Pages: 309-315
- DOI
  10.1007/s10157-022-02181-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08688, KAKENHI-PROJECT-22K19511, KAKENHI-PROJECT-23K24351
[Journal Article] Vaccination against connective tissue growth factor attenuates the development of renal fibrosis.2022
- Author(s)
  Nakayama T, Azegami T, Hayashi K, Hishikawa A, Yoshimoto N, Nakamichi R, Sugita E, Itoh H
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 10933-10933
- DOI
  10.1038/s41598-022-15118-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08263, KAKENHI-PROJECT-21K18270, KAKENHI-PROJECT-22K19511, KAKENHI-PROJECT-20H00535
[Journal Article] Epigenetic alterations in podocytes in diabetic nephropathy.2021
- Author(s)
  Sugita E, Hayashi K (corresponding author), Hishikawa A, Itoh H.
- Journal Title
  
  Front Pharmacol,
  
  Volume: 12 Pages: 759299-759299
- DOI
  10.3389/fphar.2021.759299
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08688, KAKENHI-PROJECT-21K18270
[Journal Article] Effects of high glucose and lipotoxicity on diabetic podocytes2021
- Author(s)
  Ran Nakamichi, Kaori Hayashi, Hiroshi Itoh
- Journal Title
  
  Nutrients
  
  Volume: 13(1) Issue: 1 Pages: 241-241
- DOI
  10.3390/nu13010241
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08688, KAKENHI-PROJECT-20H00535
[Journal Article] DNA repair factor KAT5 prevents ischemic acute kidney injury through glomerular filtration regulation2021
- Author(s)
  Akihito Hishikawa, Kaori Hayashi (corresponding author), Akiko Kubo, Kazutoshi Miyashita, Akinori Hashiguchi, Kenichiro Kinouchi, Norifumi Yoshimoto, Ran Nakamichi, Riki Akashio, Erina Sugita, Tatsuhiko Azegami, Toshiaki Monkawa, Makoto Suematsu, Hiroshi Itoh.
- Journal Title
  
  iScience.
  
  Volume: 24(12) Issue: 12 Pages: 103436-103436
- DOI
  10.1016/j.isci.2021.103436
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08688, KAKENHI-PROJECT-20H00535, KAKENHI-PROJECT-21K06876, KAKENHI-PROJECT-21K18270, KAKENHI-PROJECT-20K17291
[Journal Article] Vaccination against receptor for advanced glycation end products attenuates the progression of diabetic kidney disease.2021
- Author(s)
  Azegami T, Nakayama T, Hayashi K, Hishikawa A, Yoshimoto N, Nakamichi R, Itoh H.
- Journal Title
  
  Diabetes.
  
  Volume: 70(9) Issue: 9 Pages: 2147-2158
- DOI
  10.2337/db20-1257
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08688, KAKENHI-PROJECT-20H00535, KAKENHI-PROJECT-21K18270
[Journal Article] DNA damage and expression of DNA methylation modulators in urine-derived cells of patients with hypertension and diabetes2020
- Author(s)
  Hishikawa Akihito、Hayashi Kaori、Yoshimoto Norifumi、Nakamichi Ran、Homma Koichiro、Itoh Hiroshi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1
- DOI
  10.1038/s41598-020-60420-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08688, KAKENHI-PROJECT-18J13428, KAKENHI-PROJECT-20H00535
[Journal Article] Association of glomerular DNA damage and DNA methylation with one-year eGFR decline in IgA nephropathy2020
- Author(s)
  Hayashi Kaori、Hishikawa Akihito、Hashiguchi Akinori、Azegami Tatsuhiko、Yoshimoto Norifumi、Nakamichi Ran、Tokuyama Hirobumi、Itoh Hiroshi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1
- DOI
  10.1038/s41598-019-57140-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08688, KAKENHI-PROJECT-18J13428, KAKENHI-PROJECT-20H00535
[Journal Article] Decreased KAT5 Expression Impairs DNA Repair and Induces Altered DNA Methylation in Kidney Podocytes2019
- Author(s)
  Hishikawa Akihito、Hayashi Kaori、Abe Takaya、Kaneko Mari、Yokoi Hideki、Azegami Tatsuhiko、Nakamura Mari、Yoshimoto Norifumi、Kanda Takeshi、Sakamaki Yusuke、Itoh Hiroshi
- Journal Title
  
  Cell Reports
  
  Volume: 26 Issue: 5 Pages: 1318-1332
- DOI
  10.1016/j.celrep.2019.01.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09697, KAKENHI-PROJECT-18J13428, KAKENHI-PROJECT-16K19496, KAKENHI-PROJECT-19K08688, KAKENHI-PROJECT-17H06270
[Journal Article] DNA Damage Repair and DNA Methylation in the Kidney2019
- Author(s)
  Hayashi Kaori、Hishikawa Akihito、Itoh Hiroshi
- Journal Title
  
  American Journal of Nephrology
  
  Volume: 50 Issue: 2 Pages: 81-91
- DOI
  10.1159/000501356
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08688, KAKENHI-PROJECT-18J13428
[Journal Article] Pre-emptive medicine for hypertension and its prospects2018
- Author(s)
  Itoh Hiroshi、Hayashi Kaori、Miyashita Kazutoshi
- Journal Title
  
  Hypertension Research
  
  Volume: 42 Issue: 3 Pages: 301-305
- DOI
  10.1038/s41440-018-0177-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06270, KAKENHI-PROJECT-16K19496, KAKENHI-PROJECT-17K09735
[Journal Article] Intranasal vaccination against angiotensin II type 1 receptor and pneumococcal surface protein A attenuates hypertension and pneumococcal infection in rodents.2018
- Author(s)
  Tatsuhiko Azegami, Yoshikazu Yuki, Kaori Hayashi, Akihito Hishikawa, Shin-ichi Sawada, Kazuya Ishige, Kazunari Akiyoshi, Hiroshi Kiyono, Hiroshi Itoh.
- Journal Title
  
  J Hypertens
  
  Volume: 36 (2) Issue: 2 Pages: 387-394
- DOI
  10.1097/hjh.0000000000001519
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19496, KAKENHI-PROJECT-17H06270
[Journal Article] Transcription factors as therapeutic targets in chronic kidney disease2018
- Author(s)
  Akihito Hishikawa, Kaori Hayashi* and Hiroshi Itoh（*corresponding author）
- Journal Title
  
  Molecules
  
  Volume: 23 Issue: 5 Pages: 1123-1123
- DOI
  10.3390/molecules23051123
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19496
[Journal Article] Relationship between sarcopenic obesity and metabolic syndrome among Japanese elderly who underwent a comprehensive health checkup2017
- Author(s)
  Michiyo Takayama, Koichiro Azuma, Kaori Hayashi, Ryoko Shimizu-Hirota, Kanako Makino, Rieko Bessho, Toshifumi Yoshida, Kazuhiro Kashiwagi, Hiroshi Hirose, Nagamu Inoue, Yasushi Iwao
- Journal Title
  
  Japan Society of Health Evaluation and Promotion
  
  Volume: 44 (4) Pages: 587-593
- NAID
  130005877901
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19496
[Journal Article] Investigation of Metabolic Factors Associated with eGFR Decline Over 1 Year in a Japanese Population without CKD2017
- Author(s)
  Hayashi K, Takayama M, Abe T, Kanda T, Hirose H, Shimizu-Hirota R, Shiomi E, Iwao Y, and Itoh H.
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 24 Issue: 8 Pages: 863-875
- DOI
  10.5551/jat.38612
- NAID
  130005876085
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08564, KAKENHI-PROJECT-16K10668, KAKENHI-PROJECT-16K19496
[Journal Article] Association of Kidney Dysfunction With Asymptomatic Cerebrovascular Abnormalities in a Japanese Population With Health Checkups2017
- Author(s)
  Kaori Hayashi*, Michiyo Takayama, Takeshi Kanda, Kazuhiro Kashiwagi, Akihito Hishikawa, Yasushi Iwao, and Hiroshi Itoh
- Journal Title
  
  Circ J
  
  Volume: 81 Issue: 8 Pages: 1191-1197
- DOI
  10.1253/circj.CJ-17-0140
- NAID
  130005859040
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19496
[Journal Article] Renin-angiotensin blockade resets podocyte epigenome through Kruppel-like Factor 4 and attenuates proteinuria.2015
- Author(s)
  Hayashi K, Sasamura H, Nakamura M, Sakamaki Y, Azegami T, Oguchi H, Tokuyama H, Wakino S, Hayashi K, Itoh H
- Journal Title
  
  Kidney Int
  
  Volume: 88(4) Issue: 4 Pages: 745-753
- DOI
  10.1038/ki.2015.178
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461236, KAKENHI-PROJECT-25860687
[Journal Article] Transcription factors and epigenetic modulation – its therapeutic implication in chronic kidney disease (CKD)2015
- Author(s)
  Kaori Hayashi, Hiroshi Itoh
- Journal Title
  
  Arch Immunol Ther Exp
  
  Volume: 63(3) Pages: 193-196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860687
[Journal Article] ポドサイトにおけるエピジェネティック調節2015
- Author(s)
  林　香、伊藤　裕
- Journal Title
  
  腎と透析
  
  Volume: 3月号 Pages: 369-372
- Data Source
  KAKENHI-PROJECT-25860687
[Journal Article] Transcription factors and epigenetic modulation; its therapeutic implication in chronic kidney disease (CKD)2015
- Author(s)
  Kaori Hayashi*, Hiroshi Itoh
- Journal Title
  
  Arch Immunol Ther Exp
  
  Volume: 63 (3) Issue: 3 Pages: 193-196
- DOI
  10.1007/s00005-014-0326-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860687
[Journal Article] KLF4-dependent epigenetic remodeling modulates podocyte phenotype and attenuates proteinuria2014
- Author(s)
  Kaori Hayashi, Hiroyuki Sasamura, Mari Nakamura, Tatsuhiko Azegami, Hideyo Oguchi, Yusuke Sakamaki, Hiroshi Itoh
- Journal Title
  
  J Clin Invest
  
  Volume: 124 (6) Issue: 6 Pages: 2523-2537
- DOI
  10.1172/jci69557
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860687
[Journal Article] Renal arteriolar injury by salt intake causes ‘Salt Memory’ for the development of hypertension.2014
- Author(s)
  Hideyo Oguchi, Hiroyuki Sasamura, Kazunobu Shinoda, Shinya Morita, Hidaka Kono, Ken Nakagawa, Kimiko Ishiguro, Kaori Hayashi, Mari Nakamura, Tatsuhiko Azegami, Mototsugu Oya, Hiroshi Itoh.
- Journal Title
  
  Hypertension
  
  Volume: 64(4) Issue: 4 Pages: 784-791
- DOI
  10.1161/hypertensionaha.113.02973
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860687, KAKENHI-PROJECT-26860647
[Journal Article] 山中因子KLF4による糸球体上皮細胞遺伝子のエピジェネティック調節2014
- Author(s)
  林　香、篠村裕之、伊藤裕
- Journal Title
  
  Annual Review腎臓2014年
  
  Volume: 2014年 Pages: 117-122
- Data Source
  KAKENHI-PROJECT-25860687
[Journal Article] Vaccination against the angiotensin type I receptor for the prevention of L-NAME induced nephropathy2012
- Author(s)
  Tatsuhiko Azegami, Hiroyuki Sasamura, Kaori Hayashi, Hiroshi Itoh
- Journal Title
  
  Hypertension Research
  
  Volume: 35 Pages: 492-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890205
[Journal Article] Regression of atherosclerosis in apolipoprotein-E deficient mice is feasible using high-dose angiotensin receptor blocker, candesartan2012
- Author(s)
  Kaori Hayashi, Hiroyuki Sasamura, Tatsuhiko Azegami, Hiroshi Itoh
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: (印刷中)
- NAID
  130004444629
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890205
[Journal Article] Regression of atherosclerosis in apolipoprotein-E deficient mice is feasible using high-dose angiotensin receptor blocker, candesartan2012
- Author(s)
  Kaori Hayashi
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 19(8) Pages: 736-46
- NAID
  130004444629
- Data Source
  KAKENHI-PROJECT-23890205
[Journal Article] Regression of atherosclerosis in apolipoprotein-E deficient mice is feasible using high-dose angiotensin receptor blocker2012
- Author(s)
  Kaori Hayashi, Hiroyuki Sasamura, Tatsuhiko Azegami,Hiroshi Itoh
- Journal Title
  
  candesartan Journal of Atherosclerosis and Thrombosis
  
  Volume: 19 Pages: 736-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890205
[Journal Article] Vaccination against the angiotensin type I receptor for the prevention of L-NAME induced nephropathy2012
- Author(s)
  Tatsuhiko Azegami, Hiroyuki Sasamura, Kaori Hayashi, Hiroshi Itoh
- Journal Title
  
  Hyertension Research
  
  Volume: (印刷中) Issue: 5 Pages: 492-499
- DOI
  10.1038/hr.2011.212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890205, KAKENHI-PROJECT-23591225
[Journal Article] Use of serum and urine metabolome analysis for the detection of metabolic changes in patients with stage 1-2 chronic kidney disease2011
- Author(s)
  Kaori Hayashi, Hiroyuki Sasamura, Takako Hishiki, Makoto Suematsu, Satsuki Ikeda, Tomoyoshi Soga, Hiroshi Itoh
- Journal Title
  
  Nephro-Urology Monthly
  
  Volume: 3 Pages: 164-171
- URL
  http://numonthly.com/?page=article&article_id=1255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890205
[Journal Article] 'Pulse' treatment with angiotensin blocker reverses renal arteriolar hypertrophy and regresses hypertension2009
- Author(s)
  Kimiko Ishiguro, Kaori Hayashi, Hiroyuki Sasamura, Yusuke Sakamaki, Hiroshi Itoh
- Journal Title
  
  Hypertension Jan
  
  Pages: 83-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790578
[Journal Article] 'Pulse' treatment with angiotensin blocker reverses renal arteriolar ypertrophy and regresses hypertension.2009
- Author(s)
  Kimiko Ishiguro, Kaori Hayashi, Hiroyuki Sasamura, Yusuke Sakamaki, Hiroshi Itoh.
- Journal Title
  
  Hypertension
  
  Pages: 83-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790578
[Journal Article] Differential effects of transient treatment of spontaneously hypertensive rats with various antihypertensive agents on the subsequent development of diabetic nephropathy2008
- Author(s)
  Kimiko Ishiguro, Hiroyuki Sasamura, Yusuke Sakamaki, Kaori Hayashi, and Hiroshi Itoh
- Journal Title
  
  Nephron 109
  
  Pages: 20-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790578
[Journal Article] Differential effects of transient treatment of spontaneously hypertensive rats with various antihypertensive agents on the subsequent development of diabetic nephropathy2008
- Author(s)
  Kimiko Ishiguro, Hiroyuki Sasamura, Yusuke Sakamaki, Kaori Hayashi, and Hiroshi Itoh.
- Journal Title
  
  Nephron 109
  
  Pages: 20-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] DNA Double-Strand Breaks in Proximal Tubular Epithelial Cells Induce a Systemic Lipodystrophy-Like Phenotype2023
- Author(s)
  Erina Sugita Nishimura , Akihito Hishikawa, Ran Nakamichi, Eriko Yoshida Hama, Kaori Hayashi
- Organizer
  American Society of Nephrology Kidney Week 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07705
[Presentation] 近位尿細管上皮細胞におけるDNA損傷修復は全身の代謝変容を惹起する2023
- Author(s)
  西村　絵里那、林　香、菱川　彰人、中道　蘭、吉本　憲史、吉田　英莉子、伊藤　裕
- Organizer
  第66回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-23K07705
[Presentation] Continuous non-mutagenic DNA damage in podocytes activates inflammatory response and may accelerate kidney aging2021
- Author(s)
  Ran Nakamichi, Akihito Hishikawa, Kaori Hayashi, Toshiaki Monkawa, Hiroshi Itoh
- Organizer
  ASN Kidney Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08688
[Presentation] DNA damage repair and altered epigenome in the kidney: as useful markers and therapeutic targets2021
- Author(s)
  Kaori Hayashi
- Organizer
  第64回日本腎臓学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08688
[Presentation] 糖尿病腎症とエピゲノム～ポドサイトにおけるKAT5発現とDNAメチレーション2020
- Author(s)
  林　香
- Organizer
  第63回日本糖尿病学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08688
[Presentation] AKIプレコンディショニング効果におけるDNA修復因子KAT5の役割の検討2020
- Author(s)
  菱川彰人　林　香　他
- Organizer
  第63回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08688
[Presentation] ポドサイトにおけるDNA損傷2020
- Author(s)
  林　香
- Organizer
  第93回日本内分泌学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08688
[Presentation] DNA repair factor KAT5 acts against ischemia-reperfusion injury through promoted DNA repair and KCC3-dependent TGF regulation in proximal tubular cells2020
- Author(s)
  Akihito Hishikawa, Kaori Hayashi, et al.
- Organizer
  ASN Kidney Week 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08688
[Presentation] Analysis of DNA repair factor KAT5 and DNA methylation modulators in urinary shedding cells of patients with diabetic kidney disease2019
- Author(s)
  Akihito Hishikawa, Kaori Hayashi, Hiroshi Itoh
- Organizer
  ASN Kidney Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08688
[Presentation] 腎糸球体ポドサイトにおけるDNA修復因子KAT5の発現低下はDNAメチル化変化を惹起し、糖尿病性腎症の病態に関与する2019
- Author(s)
  菱川彰人、林　香、中村真理、畔上達彦、吉本憲史、伊藤裕
- Organizer
  抗加齢学会学術総会（最優秀演題賞受賞）
- Data Source
  KAKENHI-PROJECT-19K08688
[Presentation] 腎ポドサイトにおけるKAT5発現低下はDNA 修復不全およびDNA メチル化変化を惹起する2019
- Author(s)
  菱川彰人、林　香、畔上達彦、吉本憲史、伊藤裕
- Organizer
  日本高血圧学会総会（YIA受賞）
- Data Source
  KAKENHI-PROJECT-19K08688
[Presentation] DNA修復因子KAT5を介したエピゲノム調節機構はポドサイトの形質維持に必須であり、糖尿病性腎症新規治療標的となり得る2019
- Author(s)
  菱川彰人、林　香、中村真理、畔上達彦、吉本憲史、伊藤裕
- Organizer
  内分泌学会総会（YIA受賞）
- Data Source
  KAKENHI-PROJECT-19K08688
[Presentation] 尿中DNA修復因子KAT5/podocinの糖尿病患者における検討2019
- Author(s)
  菱川彰人、林　香、中村真理、畔上達彦、吉本憲史、伊藤裕
- Organizer
  抗加齢学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08688
[Presentation] エピゲノム変化と慢性腎臓病病態との関連2019
- Author(s)
  林　香、伊藤裕
- Organizer
  抗加齢学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08688
[Presentation] 高血圧、糖尿病患者の尿中脱落細胞におけるDNA修復因子KAT5およびDNAメチル化修飾因子の解析2019
- Author(s)
  菱川彰人、林　香、畔上達彦、吉本憲史、伊藤裕
- Organizer
  日本高血圧学会総会（YIP受賞）
- Data Source
  KAKENHI-PROJECT-19K08688
[Presentation] 糖尿病患者尿中脱落細胞におけるDNA修復因子KAT5, エピゲノム修飾因子の解析2019
- Author(s)
  菱川彰人、林　香、中村真理、畔上達彦、吉本憲史、伊藤裕
- Organizer
  日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08688
[Presentation] Decreased KAT5 expression impairs DNA repair and induces DNA methylation in diabetic nephropathy podocytes.2018
- Author(s)
  Akihito Hishikawa, Kaori Hayashi, Norifumi Yoshimoto, Hiroshi Itoh.
- Organizer
  ASN kidney week 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19496
[Presentation] DNA修復因子KAT5はポドサイトの形質維持に必須であり、その低下が糖尿病性腎症の病態に関与する2018
- Author(s)
  菱川彰人、林　香、中村真理、畔上達彦、吉本憲史、伊藤裕
- Organizer
  第41回日本高血圧学会
- Data Source
  KAKENHI-PROJECT-16K19496
[Presentation] KAT5 plays a key role in DNA damage repair and epigenetic regulation in kidney podocytes2018
- Author(s)
  Akihito Hishikawa, Kaori Hayashi, Hiroshi Itoh.
- Organizer
  International Society of Hypertension
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19496
[Presentation] DNA修復因子KAT5はポドサイトの形質維持に必須である2018
- Author(s)
  菱川彰人、林　香、中村真理、畔上達彦、吉本憲史、伊藤裕
- Organizer
  第61回日本腎臓学会
- Data Source
  KAKENHI-PROJECT-16K19496
[Presentation] ポドサイト形質のエピゲノム調節機構とCKDの病態における役割2017
- Author(s)
  林　香
- Organizer
  第2回ポドサイト研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16K19496
[Presentation] DNA damage response and epigenetic changes in ‘cardiometabolic memory’2017
- Author(s)
  Kaori Hayashi
- Organizer
  American Heart Association Council on Hypertension
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19496
[Presentation] Kruppel-like factor 4 and Epigenetic Phenotypic Podocyte Modulation2017
- Author(s)
  Kaori Hayashi
- Organizer
  American Society of Nephrology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19496
[Presentation] アンジオテンシン阻害薬のエピゲノム変化への修復効果2016
- Author(s)
  林　香
- Organizer
  第39回日本高血圧学会総会、SHR学会合同シンポジウム
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-10-01
- Invited
- Data Source
  KAKENHI-PROJECT-16K19496
[Presentation] Epigenetic change in glomerular podocytes of proteinuric CKD patients with angiotensin receptor blocker (ARB) treatment2016
- Author(s)
  Kaori Hayashi
- Organizer
  International Society of Hypertension
- Place of Presentation
  Coex (Seoul, Korea）
- Year and Date
  2016-09-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19496
[Presentation] 高血圧治療におけるレニンアンジオテンシン系抑制によるメモリー効果2016
- Author(s)
  林　香
- Organizer
  第39回日本高血圧学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-10-02
- Invited
- Data Source
  KAKENHI-PROJECT-16K19496
[Presentation] アンジオテンシン拮抗薬による転写因子KLF4を介した糸球体ポドサイトのエピゲノム調節効果の検討2015
- Author(s)
  林　香、篠村裕之、中村真理、畔上達彦、小口英世、坂巻裕介、徳山博文、脇野修、
- Organizer
  第88回日本内分泌学会学術総会
- Place of Presentation
  ホテルニューオータニ（東京都千代田区）
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-25860687
[Presentation] RAS抑制薬はKLF4を介してポドサイトのエピゲノムを調節する2015
- Author(s)
  林　香、篠村裕之、中村真理、畔上達彦、小口英世、坂巻裕介、徳山博文、脇野修、
- Organizer
  第58回日本腎臓学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-06-06
- Data Source
  KAKENHI-PROJECT-25860687
[Presentation] アンジオテンシン受容体拮抗薬による腎糸球体ポドサイトのエピジェネティック調節効果の検討2015
- Author(s)
  林　香、篠村裕之、中村真理、畔上達彦、小口英世、坂巻裕介、徳山博文、脇野修、林晃一、伊藤裕
- Organizer
  第20回アンジオテンシンカンファレンス
- Place of Presentation
  都市センターホテル（東京）
- Year and Date
  2015-02-07
- Data Source
  KAKENHI-PROJECT-25860687
[Presentation] KLF4とKLF15は相補的にポドサイト形質維持に関与する2014
- Author(s)
  林　香、篠村裕之、中村真理、畔上達彦、小口英世、伊藤裕
- Organizer
  第57回日本腎臓学会総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-07-04
- Data Source
  KAKENHI-PROJECT-25860687
[Presentation] 山中因子KLF4による糸球体上皮細胞の上皮・間葉系マーカー遺伝子のエピジェネティック調節機構の検討2014
- Author(s)
  林　香、篠村裕之、中村真理、畔上達彦、小口英世、伊藤裕
- Organizer
  第51回分子臨床医学会学術総会
- Place of Presentation
  東京国際フォーラム（東京）
- Year and Date
  2014-04-11
- Data Source
  KAKENHI-PROJECT-25860687
[Presentation] アンジオテンシン受容体拮抗薬(ARB)高用量投与による動脈硬化の退縮とその機序の検討2012
- Author(s)
  林香、篠村裕之、畔上達彦、小口英世、中村真理、石黒喜美子、伊藤裕
- Organizer
  第17回アンジオテンシンカンファレンス
- Place of Presentation
  大阪
- Year and Date
  2012-02-04
- Data Source
  KAKENHI-PROJECT-23890205
[Presentation] 山中因子 KLF4 は腎糸球体上皮細胞に発現し、尿蛋白バリアの形成とアンジオテンシン受容体拮抗薬の抗蛋白尿作用に関与する2012
- Author(s)
  林香、篠村裕之、吉田理、中村真理、畔上達彦、小口英世、伊藤裕
- Organizer
  第35回日本高血圧学会総会
- Place of Presentation
  名古屋(トップ10演題選出)
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-23890205
[Presentation] アンジオテンシン受容体拮抗薬高用量投与による動脈硬化退縮の検討2012
- Author(s)
  篠村裕之、林香、畔上達彦、小口英世、中村真理、伊藤裕
- Organizer
  第16回心血管内分泌学会総会
- Place of Presentation
  東京
- Year and Date
  2012-11-23
- Data Source
  KAKENHI-PROJECT-23890205
[Presentation] Regression of atherosclerosis in apolipoprotein-E deficient mice is feasible using high-dose angiotensin receptor blocker.2012
- Author(s)
  Kaori Hayashi
- Organizer
  International Society of Hypertension
- Place of Presentation
  Sydney, Australia
- Data Source
  KAKENHI-PROJECT-23890205
[Presentation] 山中因子 KLF4 は糸球体ポドサイトに発現し上皮形質維持に重要である2012
- Author(s)
  林香、篠村裕之、吉田理、中村真理、畔上達彦、小口英世、伊藤裕
- Organizer
  第55回日本腎臓学会総会
- Place of Presentation
  横浜(会長賞受賞)
- Year and Date
  2012-06-01
- Data Source
  KAKENHI-PROJECT-23890205
[Presentation] Regression of atherosclerosis in apolipoprotein-E deficient mice is feasible using high-dose angiotensin receptor blocker2012
- Author(s)
  Kaori Hayashi, Hiroyuki Sasamura, Tatsuhiko Azegami, Hideyo Oguchi, Mari Nakamura, Kimiko Ishiguro, Hiroshi Itoh
- Organizer
  International Society of Hypertension
- Place of Presentation
  Sydney, Australia
- Year and Date
  2012-10-04
- Data Source
  KAKENHI-PROJECT-23890205
[Presentation] ARB高用量投与による自然発症高脂血症マウス(SHL)の糸球体病変退縮効果の検討2011
- Author(s)
  林香
- Organizer
  第54回日本腎臓学会総会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-23890205
[Presentation] ARB 高用量投与による自然発症高脂血症マウス(SHL)の糸球体病変退縮効果の検討2011
- Author(s)
  林香、篠村裕之、畔上達彦、石黒喜美子、中村真理、伊藤裕
- Organizer
  第54回日本腎臓学会総会
- Place of Presentation
  横浜
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-23890205
[Presentation] アンジオテンシン受容体拮抗薬高用量投与による動脈硬化の退縮(reversal)と機序の検討2011
- Author(s)
  林香
- Organizer
  第34回日本高血圧学会総会
- Place of Presentation
  栃木県総合文化センター・宇都宮東武ホテルグランデ(栃木)
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-23890205
[Presentation] アンジオテンシン受容体拮抗薬(ARB)高用量投与による動脈硬化の退縮(reversal)と機序の検討2011
- Author(s)
  林香、篠村裕之、畔上達彦、石黒喜美子、中村真理、伊藤裕
- Organizer
  第34回日本高血圧学会総会
- Place of Presentation
  宇都宮
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-23890205
[Presentation] 高血圧発症抑制とのアンジオテンシン抑制薬の「一過性パルス投与」による高血圧の退行(regression)の検討2008
- Author(s)
  石黒喜美子、篠村裕之、坂巻裕介、林香、伊藤裕
- Organizer
  アンジオテンシンカンファレンス
- Place of Presentation
  大阪
- Year and Date
  2008-02-02
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] Effects of' pulse 'treatment with high-dose angiotensin receptor blocker (ARB) or calcium channel blocker (CCB) on regression of hypertension and renal microvascular remodeling in spontaneously hypertensive rats (SHR)2008
- Author(s)
  Kimiko Ishiguro, Kaori Hayashi, Hiroyuki Sasamura, Yusuke Sakamaki, and Hiroshi Itoh
- Organizer
  Effects of' pulse 'treatment with high-dose angiotensin receptor blocker (ARB) or calcium channel blocker (CCB) on regression of hypertension and renal microvascular remodeling in spontaneously hypertensive rats (SHR)
- Place of Presentation
  Berlin
- Year and Date
  2008-06-19
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] ARB'一過性高用量パルス投与'による高血圧の退行(regression)療法の開発2008
- Author(s)
  石黒喜美子,林香,篠村裕之,坂巻裕介,伊藤裕
- Organizer
  第44回高血圧関連疾患モデル学会学術総会
- Place of Presentation
  出雲
- Year and Date
  2008-11-22
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] ARB高用量パルス投与は高血圧モデル動物において高血圧の著明な退行(regression)とともに心血管肥大の抑制をもたらす2008
- Author(s)
  石黒喜美子,林香,篠村裕之,坂巻裕介,伊藤裕
- Organizer
  第12回心血管内分泌学会学術総会
- Place of Presentation
  熊本
- Year and Date
  2008-11-29
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] 高血圧発症後のACE阻害薬・ARB「一過性パルス療法」による高血圧の退行(regression)の検討2008
- Author(s)
  石黒喜美子,篠村裕之,坂巻裕介,林香,伊藤裕,
- Organizer
  第31回日本高血圧学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] メタボリックシンドローム(MetS)モデルラットにおける'アンジオテンシン受容体拮抗薬(ARB)一過性パルス投与'による血圧・肥満・インスリ抵抗性体質の退行(regression)2008
- Author(s)
  石黒喜美子、篠村裕之、坂巻裕介、林香、猿田享男、伊藤裕
- Organizer
  第81回日本内分泌学会学術総会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] メタボリックシンドローム(MetS)モデルラットにおける'アンジオテンシン受容体拮抗薬(ARB)一過性パルス投与'による血圧・肥満・インスリン抵抗性体質の退行(regression)2008
- Author(s)
  石黒喜美子、篠村裕之、坂巻裕介、林香、猿田享男、伊藤裕
- Organizer
  第81回日本内分泌学会学術総会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] Effects of 'pulse' treatment with high-dose angiotensin receptor blocker (ARB) or calcium channel blocker (CCB) on regression of hypertension and renal microvascular remodeling in spontaneously hypertensive rats (SHR)2008
- Author(s)
  Kimiko Ishiguro, Kaori Hayashi, Hiroyuki Sasamura, Yusuke Sa kamaki, and Hiroshi Itoh
- Organizer
  The 22nd Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Berlin
- Year and Date
  2008-06-19
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] アンジオテンシン受容体拮抗薬およびアルドステロン拮抗薬の早期一過性投与による糖尿病性腎症発症抑制効果の比較検討2008
- Author(s)
  石黒喜美子、篠村裕之、坂巻裕介、林香、猿田享男、伊藤裕
- Organizer
  第51回日本腎臓学会学術総会
- Place of Presentation
  福岡
- Year and Date
  2008-05-30
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] レニンーアンジオテンシン系抑制薬の「一過性パルス投与」による高血圧退行療法(regression therapy)の開発とカルシウム桔抗薬との比較検討2007
- Author(s)
  石黒喜美子、篠村裕之、坂巻裕介、林香、伊藤裕
- Organizer
  日本高血圧学会
- Place of Presentation
  沖縄
- Year and Date
  2007-10-26
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] Hiroshi Itoh Effects of Transient Exposure to Angiotensin or Aldosterone Antagonist During the 'Critical Period' on the Later Development of Nephropathy in Streptozotocin-induced Diabetic Rats2007
- Author(s)
  Kimiko Ishiguro, Hiroyuki Sasamura, Yusuke Sakamaki, Kaori Hayashi, Takao Saruta
- Organizer
  Hiroshi Itoh Effects of Transient Exposure to Angiotensin or Aldosterone Antagonist During the 'Critical Period' on the Later Development of Nephropathy in Streptozotocin-induced Diabetic Rats
- Place of Presentation
  サンフランシスコ
- Year and Date
  2007-11-02
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] Hiroshi Itoh Use ofTransient 'Pulse' Therapy with High-Dose Antihypertensive Agents to Induce Regression of Established Hypertension in Spontaneously Hypertensive Rats2007
- Author(s)
  Kimiko Ishiguro, Hiroyuki Sasamura, Yusuke Sakamaki, Kaori Hayashi, Takao Saruta
- Organizer
  American Society of Nephrology
- Place of Presentation
  サンフランシスコ
- Year and Date
  2007-11-02
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] レニンーアンジオテンシン系抑制薬の「一過性パルス投与」による高血圧退行療法(regression therapy)の開発とカルシウム拮抗薬との比較検討2007
- Author(s)
  石黒喜美子、篠村裕之、坂巻裕介、林香、伊藤裕
- Organizer
  日本高血圧学会学術総会
- Place of Presentation
  沖縄
- Year and Date
  2007-10-26
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] アンジオテンシン受容体拮抗薬の早期一過性投与による糖尿病性腎症発症抑制効果の検討2007
- Author(s)
  石黒喜美子、篠村裕之、坂巻裕介、林香、猿田享男、伊藤裕
- Organizer
  心血管内分泌学会学術総会
- Place of Presentation
  品川
- Year and Date
  2007-11-16
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] Effects of Transient Exposure to Angiotensin or Aldosterone Ant agonist During the 'Critical Period'on the Later Development of Nephropathy in Streptozotocin-induced Diabetic Rats2007
- Author(s)
  Kimiko Ishiguro, Hirojmki Sasamura, Yusiike Sakamaki, Kaori Hayashi, Takao Saruta, Hiroshi Itoh
- Organizer
  Americaa Society of Nephrology
- Place of Presentation
  サンフランシスコ
- Year and Date
  2007-11-02
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] アンジオテンシン受容体措抗薬の早期一過性投与による糖尿病性腎症発症抑制効果の検討2007
- Author(s)
  石黒喜美子、篠村裕之、坂巻裕介、林香、猿田享男、伊藤裕
- Organizer
  心血管内分泌学会
- Place of Presentation
  品川
- Year and Date
  2007-11-16
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] Use of TVaimient 'Pulse' Therapy with High-Dose Antihypertensi ve Agents to Induce Regression of Established Hypertension in Spontaneously HTOertensive Rats。2007
- Author(s)
  Kimiko Ishiguro, Hiroyuki Sasamura, Yusuke Sakamaki, Kaori Hayashi, Takao Saruta, Hiroshi Itoh
- Organizer
  American Society of Nephrology
- Place of Presentation
  サンフランシスコ
- Year and Date
  2007-11-02
- Data Source
  KAKENHI-PROJECT-18790578
[Presentation] 山中因子KLF4は糸球体上皮細胞においてネフリン遺伝子プロモーターの選択的DNA脱メチル化を惹起し蛋白尿を抑制する
- Author(s)
  林　香、篠村裕之、中村真理、畔上達彦、小口英世、伊藤裕
- Organizer
  第56回日本腎臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25860687
[Presentation] 山中因子KLF4は腎糸球体上皮細胞に発現し、尿蛋白バリアの形成とアンジオテンシン受容体拮抗薬の抗蛋白尿作用に関与する
- Author(s)
  林　香
- Organizer
  第35回日本高血圧学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23890205
[Presentation] 山中因子KLF4は糸球体ポドサイトに発現し上皮形質維持に重要である
- Author(s)
  林　香
- Organizer
  第55回日本腎臓学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23890205

1. ITOH Hiroshi (40252457)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
2. 菱川彰人 (50867489)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
3. ISHIGURO Kimiko (20424161)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
4. SASAMURA Hiroyuki (00235293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
5. 神田武志 (80317114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 長谷川一宏 (30424162)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 脇野修 (50265823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 徳山博文 (50276250)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 楠本大 (70571727)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 林晃一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 横井秀基

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 畔上達彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 宮下和季

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hayashi Kaori 林 香

HAYASHI Kaori 林 香

Research Projects

Research Products

Co-Researchers

腎臓におけるDNA損傷修復と全身代謝変容連関の解明

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尿中細胞の深層学習・画像解析による腎疾患早期診断方法の開発Principal Investigator

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血球細胞DNAメチル化をターゲットとした慢性腎臓病新規治療戦略の開発Principal Investigator

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Spiral progression of DNA damage repair, epigenetic alterations and metabolic changes in metabolic kidney diseases

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Association of podocyte DNA damage and epigenetic alterations with renal agingPrincipal Investigator

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Epigenetic regulation through angiotensin blockade in podocytesPrincipal Investigator

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Epigenetic regulation of podocyte phenotype through KLF4Principal Investigator

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The role of Kruppel-like Factor 4 (KLF4)in glomerular podocytes and its application to the therapy of proteinuria.Principal Investigator

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Research Institution

Transient treatment with ARB can suppress the development of hypertension and nephropathy

Principal Investigator

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[Journal Article] Podocyte Ercc1 is indispensable for glomerular integrity2024

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[Journal Article] Significance of podocyte DNA damage and glomerular DNA methylation in CKD patients with proteinuria2023

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[Journal Article] DNA-damaged podocyte-CD8 T cell crosstalk exacerbates kidney injury by altering DNA methylation2023

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[Journal Article] Plasminogen activator inhibitor 1 is not a major causative factor for exacerbation in a mouse model of SARS-CoV-2 infection2023

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[Journal Article] DNA-damaged podocyte-CD8 T?cell crosstalk exacerbates kidney injury by altering DNA methylation2023

Hayashi Kaori 林香

HAYASHI Kaori 林香