HASHIMOTO Nozomi 橋本希

Researcher Number	60448371
Other IDs
Affiliation (based on the past Project Information) *help	2007 – 2010: 香川大学, 医学部, 助教
Review Section/Research Field	Except Principal Investigator Experimental pathology
Keywords	Except Principal Investigator 経気管内投与 / ラット / 中期発がん性試験法 / 肝発がん / 腫瘍 / 発がんリスク / ナノサイズ微粒子 / 二酸化チタン / 酸化銅 / GST-P positive foci … More / 経静脈投与 / 強制胃内投与 / 気管内投与 / ラット肝中期発癌試験 / ナノサイズ粒子 Less

Carcinogenic risk assessment of nano-sized particles
- Principal Investigator
  
  IMAIDA Katsumi
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kagawa University

All 2011 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] Lack of promoting effects from physical pulmonary collapse in a female A/J mouse lung tumor initiated with 4-(methylnitrosamino)-1-(3-pyridyl)-1- butanone (NNK) with remarkable mesothelial cell reactions in the thoracic cavity by the polymer.2011
- Author(s)
  Yokohira M, Hashimoto N, Yamakawa K, Saoo K, Kuno T, Imaida K.
- Journal Title
  
  Exp.Toxicol.Pathol. 63
  
  Pages: 181-185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590393
[Journal Article] Molecular analysis of carcinogen induced rodent lung tumors-Invovement of microRNA expression and Kras or EGFR mutation.2010
- Author(s)
  Yamakawa K, Kuno T, Hashimoto N, Yokohira M, Suzuki S, Nakano Y, Saoo K, Imaida, K.
- Journal Title
  
  Molecular Medicine Reports 3
  
  Pages: 141-147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590393
[Journal Article] Risk analysis of environmental chemicals on lung carcinogenesis.2010
- Author(s)
  Imaida K, Yokohira M, Hashimoto N, Kuno T.
- Journal Title
  
  Asian Pacific J Cancer Prev 11
  
  Pages: 9-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590393
[Journal Article] Potassium octatitanate fibers (TISMO) induce pleural mesothelial cell reactions with iron accumulation in female A/J mice2010
- Author(s)
  Yokohira M, Hashimoto N, Imaida K, et al.
- Journal Title
  
  Oncol.Lett. (in press)
- Data Source
  KAKENHI-PROJECT-19590393
[Journal Article] Different threshold levels for 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MelQx) initiation of lung and colon carcinogenesis and the effects of an additional initiation by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in A/J mice.2010
- Author(s)
  Suzuki S, Yokohira M, Hashimoto N, Saoo K, Matsuda Y, Yamakawa K, Nakano Y, Kuno T, Imaida K.
- Journal Title
  
  Molecular Medicine Reports 3
  
  Pages: 301-307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590393
[Journal Article] Lack of promoting effects from physical pulmonary collapse in a female A/J mouse lung tumor initiated with 4-(methylnitro-samino)-1-(3-pyridyl)-1-butanone (NNK) with remarkable mesothelial cell reactions in the thoracic cavity by the polymer2010
- Author(s)
  Yokohira M, Hashimoto N, Imaida K, et al.
- Journal Title
  
  Exp.Toxicol.Pathol. (in press)
- Data Source
  KAKENHI-PROJECT-19590393
[Journal Article] Potassium octatitanate fibers (TISMO) induce pleural mesothelial cell reactions with iron accumulation in female A/J mice.2010
- Author(s)
  Yokohira M, Hashimoto N, Yamakawa K, Suzuki S, Saoo K, Kuno T, Imaida K.
- Journal Title
  
  Oncol.Lett. 1
  
  Pages: 273-278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590393
[Journal Article] Immunohistochemically detected expression of p27kip1 and skp2 predicts survival in patients with intrahepatic cholangiocarcinomas.2009
- Author(s)
  Hashimoto N, Yachida S, Okano K, Wakabayashi H, Imaida K, Kurokohchi K, Masaki T, Kinoshita H, Tominaga M, Ajiki T, Ku Y, Okabayashi T, Hanazaki K, Hiroi M, Izumi S, Mano S, Okada S, Karasawa V, Maeba V, Suzuki Y.
- Journal Title
  
  Ann.Surg.Oncol. 16
  
  Pages: 395-403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590393
[Journal Article] A lung carcinogenic bioassay of CuO and TiO2 nanoparticles with intratracheal instillation using F344 male rats2009
- Author(s)
  Yokohira M, Hashimoto N, Imaida K, et al.
- Journal Title
  
  J.Toxicol.Pathol. 22
  
  Pages: 71-78
- NAID
  130000101848
- Data Source
  KAKENHI-PROJECT-19590393
[Journal Article] An intratracheal instillation bioassay system for detection of lung toxicity due to fine particles in F344 rats.2009
- Author(s)
  Yokohira M, Kuno T, Yamakawa K, Hashimoto N, Ninomiya F, Suzuki S, Saoo K, Imaida K.
- Journal Title
  
  J.Toxicol.Pathol. 22
  
  Pages: 1-10
- NAID
  10030977104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590393
[Journal Article] Lack of modifying effects of intra-tracheal instillation of quartz or dextran sulfate sodium (DSS) in drinking water on lung tumor development initiated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-buta none (NNK) in female A/J mice2009
- Author(s)
  Yokohira M, Hashimoto N, Imaida K, et al.
- Journal Title
  
  J.Toxicol.Pathol. 22
  
  Pages: 179-185
- Data Source
  KAKENHI-PROJECT-19590393
[Journal Article] Lack of modifying effects of intratracheal instillation of quartz or dextran sulfate sodium (DSS) in drinking water on lung tumor development initiated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in female A/J mice.2009
- Author(s)
  Yokohira M, Hashimoto N, Yamakawa K, Suzuki S, Saoo K, Kuno T, Imaida K.
- Journal Title
  
  J.Toxicol.Pathol. 22
  
  Pages: 179-185
- NAID
  10030978156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590393
[Journal Article] carcinogenic bioassay of CuO and TiO2 nanoparticles with intratracheal instillation using F344 male rats.2009
- Author(s)
  Yokohira M, Hashimoto N, Yamakawa K, Suzuki S, Saoo K, Kuno T, Imaida K. A lung
- Journal Title
  
  J.Toxicol.Pathol. 22
  
  Pages: 71-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590393
[Journal Article] Lung toxicity of 16 fine particles on intratracheal instillation in a bioassay model using F344 male rats.2008
- Author(s)
  Yokohira M, Kuno T, Yamakawa K, Hosokawa K, Matsuda Y, Hashimoto N, Suzuki S, Saoo K, Imaida K.
- Journal Title
  
  Toxicol.Pathol. 36
  
  Pages: 620-631
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590393
[Journal Article] Lack of modifying potential of 8-methoxypsoralen in the promotion or progression stages of lung carcinogenesis in A/J emale ice.2008
- Author(s)
  Kuno T, Yokohira M, Matsuda Y, Suzuki S, Hashimoto N, Yamakawa K, Saoo K, Imaida K.
- Journal Title
  
  Oncol.Rep. 20(4)
  
  Pages: 767-772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590393
[Presentation] Comparison of nano-and micro-sized particles by three different route administration using a medium-term liver carcinogenesis bioassay in F344 rats2009
- Author(s)
  橋本希
- Organizer
  2009 American Association for Cancer Research Annual Meeting
- Place of Presentation
  Colorado Convention Center, (米国)
- Year and Date
  2009-04-19
- Data Source
  KAKENHI-PROJECT-19590393
[Presentation] Comparison of nano- and micro-sized particles by three different route administrations using a medium-term liver carcinogenesis bioassay in F344 rats2009
- Author(s)
  Hashimoto N, Yokohira M, Imaida K, et al.
- Organizer
  American Association for Cancer Resaech 100^<th> Annual Meeting 2009
- Data Source
  KAKENHI-PROJECT-19590393
[Presentation] Comparison of nano- and micro-sized particles by three different route administrations using a medium-term liver carcinogenesis bioassay in F344 rats.2009
- Author(s)
  橋本希, 横平正直, 今井田克己, et al.
- Organizer
  American Association for Cancer Resaech 100^<th> Annual Meeting 2009.
- Place of Presentation
  Colorado Convention Center,(米国)
- Year and Date
  2009-04-19
- Data Source
  KAKENHI-PROJECT-19590393
[Presentation] 気管内投与によるCuOナノサイズ粒子の急性変化の検討-マイクロサイズ粒子との比較による-2009
- Author(s)
  橋本希、横平正直、今井田克己, 他
- Organizer
  第25回日本毒性病理学会
- Place of Presentation
  浜松市
- Data Source
  KAKENHI-PROJECT-19590393
[Presentation] Comparison of nano-and micro-sized particles by three different route administrations using a medium-term liver carcinogenesis bioassay in F344 rats.2009
- Author(s)
  橋本希
- Organizer
  2009 American Association for Cancer Research Annual Meeting.
- Place of Presentation
  Colorado Convention Center, Denver, Colorado. U. S. A
- Year and Date
  2009-04-19
- Data Source
  KAKENHI-PROJECT-19590393
[Presentation] 気管内投与によるCuOナノサイズ粒子の急性変化の検討-マイクロサイズ粒子との比較による-2009
- Author(s)
  橋本希, 横平正直, 今井田克己, 他
- Organizer
  第25回日本毒性病理学会
- Data Source
  KAKENHI-PROJECT-19590393
[Presentation] Intratracheal instillation of CuO nanoparticles promotes liver carcinogenesis in F344 rats.2008
- Author(s)
  橋本希, 横平正直, 今井田克己, et al.
- Organizer
  67^<th> Annual Meeting of the Japanese Cancer Association.
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19590393
[Presentation] Intratracheal instillation of CuO nanoparticles promotes liver carcinogenesis in F344 rats2008
- Author(s)
  Hashimoto N, Yokohira M, Imaida K, et al.
- Organizer
  67^<th> Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-19590393
[Presentation] Potential of inhibitory effects by D-allose, a rare sugar, on liver carcinogenesis in a rat medium-term bioassay2007
- Author(s)
  Yamakawa K, Yokohira M, Kuno T, Matsuda Y, Hashimoto N, Hosokawa K, Saoo K, Imaida K.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  東京
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19590393
[Presentation] Modulation effect of NNK-induced lung tumor by CYP2A inhibitor,8-MOP administered during promotion or progression phase2007
- Author(s)
  Kuno T, Saoo K, Yokohira M, Yamakawa K, Hashimoto N, Hosokawa K. Matsuda Y. Imaida K
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  東京
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19590393
[Presentation] Expression of p27 and Skp2 predicts postoperative survival for patients with intrahepatic2007
- Author(s)
  Hashimoto N, Yachida S, Okano K, Wakabayashi H, Imaida K, Suzuki Y
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  東京
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19590393

1. IMAIDA Katsumi (90160043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 24 results
2. KUNO Toshiya (00345779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
3. YOKOHIRA Masanao (70403780)

# of Collaborated Projects: 1 results

# of Collaborated Products: 22 results
4. INOUE Tatsushi (80384593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HASHIMOTO Nozomi 橋本 希

Research Projects

Research Products

Co-Researchers

Carcinogenic risk assessment of nano-sized particles

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Lack of promoting effects from physical pulmonary collapse in a female A/J mouse lung tumor initiated with 4-(methylnitrosamino)-1-(3-pyridyl)-1- butanone (NNK) with remarkable mesothelial cell reactions in the thoracic cavity by the polymer.2011

Author(s)

Journal Title

Data Source

[Journal Article] Molecular analysis of carcinogen induced rodent lung tumors-Invovement of microRNA expression and Kras or EGFR mutation.2010

Author(s)

Journal Title

Data Source

[Journal Article] Risk analysis of environmental chemicals on lung carcinogenesis.2010

Author(s)

Journal Title

Data Source

[Journal Article] Potassium octatitanate fibers (TISMO) induce pleural mesothelial cell reactions with iron accumulation in female A/J mice2010

Author(s)

Journal Title

Data Source

[Journal Article] Different threshold levels for 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MelQx) initiation of lung and colon carcinogenesis and the effects of an additional initiation by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in A/J mice.2010

Author(s)

Journal Title

Data Source

[Journal Article] Lack of promoting effects from physical pulmonary collapse in a female A/J mouse lung tumor initiated with 4-(methylnitro-samino)-1-(3-pyridyl)-1-butanone (NNK) with remarkable mesothelial cell reactions in the thoracic cavity by the polymer2010

Author(s)

Journal Title

Data Source

[Journal Article] Potassium octatitanate fibers (TISMO) induce pleural mesothelial cell reactions with iron accumulation in female A/J mice.2010

Author(s)

Journal Title

Data Source

[Journal Article] Immunohistochemically detected expression of p27kip1 and skp2 predicts survival in patients with intrahepatic cholangiocarcinomas.2009

Author(s)

Journal Title

Data Source

[Journal Article] A lung carcinogenic bioassay of CuO and TiO2 nanoparticles with intratracheal instillation using F344 male rats2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] An intratracheal instillation bioassay system for detection of lung toxicity due to fine particles in F344 rats.2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Lack of modifying effects of intra-tracheal instillation of quartz or dextran sulfate sodium (DSS) in drinking water on lung tumor development initiated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-buta none (NNK) in female A/J mice2009

Author(s)

Journal Title

Data Source

[Journal Article] Lack of modifying effects of intratracheal instillation of quartz or dextran sulfate sodium (DSS) in drinking water on lung tumor development initiated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in female A/J mice.2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] carcinogenic bioassay of CuO and TiO2 nanoparticles with intratracheal instillation using F344 male rats.2009

Author(s)

Journal Title

Data Source

[Journal Article] Lung toxicity of 16 fine particles on intratracheal instillation in a bioassay model using F344 male rats.2008

Author(s)

Journal Title

Data Source

[Journal Article] Lack of modifying potential of 8-methoxypsoralen in the promotion or progression stages of lung carcinogenesis in A/J emale ice.2008

Author(s)

Journal Title

Data Source

[Presentation] Comparison of nano-and micro-sized particles by three different route administration using a medium-term liver carcinogenesis bioassay in F344 rats2009

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Comparison of nano- and micro-sized particles by three different route administrations using a medium-term liver carcinogenesis bioassay in F344 rats2009

HASHIMOTO Nozomi 橋本希