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Okuda Masahiko  奥田 昌彦

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OKUDA Masahiko  奥田 昌彦

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Researcher Number 60448686
Other IDs
Affiliation (Current) 2025: 横浜市立大学, 生命医科学研究科, 特任准教授
Affiliation (based on the past Project Information) *help 2021 – 2024: 横浜市立大学, 生命医科学研究科, 特任准教授
2016 – 2019: 横浜市立大学, 生命医科学研究科, 特任准教授
2009 – 2013: Yokohama City University, 生命ナノシステム科学研究科, 特任助教
2008: Yokohama City University, 国際総合科学研究科, 特任助教
2007: Yokohama City University, 国際総合科学研究科, 客員研究員
Review Section/Research Field
Principal Investigator
Structural biochemistry / Basic Section 43020:Structural biochemistry-related
Except Principal Investigator
Basic Section 43020:Structural biochemistry-related
Keywords
Principal Investigator
NMR / 立体構造 / 基本転写因子 / RNAポリメラーゼ / タンパク質 / 転写 / 構造生物学 / タンパク複合体 / 遺伝子発現 / タンパク質間相互作用 … More / RNAポリメラーゼII / 複合体 / 溶液構造 / 天然変性領域 / 転写開始 / TFIIH / TFIIE / 基本転写 / 遣伝子発現 / 蛋白質 / 核磁気共鳴法 … More
Except Principal Investigator
NMR / ヘテロクロマチン / ユークロマチン / 構造生物学 / NMR / クロマチン構造 Less
  • Research Projects

    (7 results)
  • Research Products

    (29 results)
  • Co-Researchers

    (4 People)
  •  RNAポリメラーゼと基本転写因子TFIIHの特異的相互作用の普遍性と特異性Principal Investigator

    • Principal Investigator
      奥田 昌彦
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      Yokohama City University
  •  クロマチン中の揺らいでいる領域の機能構造解析

    • Principal Investigator
      西村 善文
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      Yokohama City University
  •  ヒトRNAポリメラーゼと基本転写因子TFIIHとの複合体の構造モデルの構築Principal Investigator

    • Principal Investigator
      奥田 昌彦
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      Yokohama City University
  •  Structural study for the complex between human RNA polymerase II and the general transcription factor TFIIH by NMRPrincipal Investigator

    • Principal Investigator
      Okuda Masahiko
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Yokohama City University
  •  NMR study for the whole structure of human general transcription factor TFIIEPrincipal Investigator

    • Principal Investigator
      OKUDA Masahiko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Yokohama City University
  •  NMR structural analysis for the whole structure of human general transcription factor, TFIIE.Principal Investigator

    • Principal Investigator
      OKUDA Masahiko
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      Yokohama City University
  •  Structural analysis of domains from human general transcription factor, TFIIE for the determination of the complete structure.Principal Investigator

    • Principal Investigator
      OKUDA Masahiko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      Yokohama City University

All 2023 2022 2021 2011 2010 2009 2008 2007

All Journal Article Presentation

  • [Journal Article] Structural polymorphism of the PH domain in TFIIH2023

    • Author(s)
      Okuda Masahiko、Nishimura Yoshifumi
    • Journal Title

      Bioscience Reports

      Volume: 43 Issue: 7

    • DOI

      10.1042/bsr20230846

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06035
  • [Journal Article] Dynamic structures of intrinsically disordered proteins related to the general transcription factor TFIIH, nucleosomes, and histone chaperones2022

    • Author(s)
      Okuda Masahiko、Tsunaka Yasuo、Nishimura Yoshifumi
    • Journal Title

      Biophysical Reviews

      Volume: 14 Issue: 6 Pages: 1449-1472

    • DOI

      10.1007/s12551-022-01014-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K06021, KAKENHI-PROJECT-21K06035, KAKENHI-PROJECT-18K06064
  • [Journal Article] Structural insight into the TFUE/THIE1 interaction : TFIIE and p53 share the binding region on TFIIH2008

    • Author(s)
      Okuda, M., Tanaka, A, Satoh, M., Mizuta, S., Takazawa, M., Ohkuma, Y., Nishimura, Y.
    • Journal Title

      The EMBO Journal 27

      Pages: 1161-1171

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19770090
  • [Journal Article] Novel structural and functional mode of a knot essential for RNA binding activity of the Esal presumed chromodomain2008

    • Author(s)
      Shimojo, H., Sano, N., Moriwaki, Y., Okuda, M., Horikoshi, M., Nishimura, Y.
    • Journal Title

      Journal of Molecular Biology 378

      Pages: 987-1001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19770090
  • [Journal Article] Novel structural and functional mode of a knot essential for RNA binding activity of the Esa1 presumed chromodomain.2008

    • Author(s)
      Shimojo, H., Sano, N., Moriwaki, Y., Okuda, M., Horikoshi, M., Nishimura, Y.
    • Journal Title

      J. Mol. Biol. 378

      Pages: 987-1001

    • Data Source
      KAKENHI-PROJECT-19770090
  • [Journal Article] Structural characterization of human general transcription factor TFIIF in solution2008

    • Author(s)
      Akashi, S., Nagakura, S., Yamamoto, S., Okuda, M., Ohkuma, Y., Nishimura, Y.
    • Journal Title

      Protein Science 17

      Pages: 389-400

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19770090
  • [Journal Article] Structural insight into the TFIIE-TFIIH interaction: TFIIE and p53 share the binding region on TFIIH.2008

    • Author(s)
      Okuda M., Tanaka A., Satoh M., Mizuta S., Takazawa M., Ohkuma Y., Nishimura Y.
    • Journal Title

      The EMBO Journal 27

      Pages: 1161-1171

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19770090
  • [Journal Article] Structural insight into the TFIIE/TFIIH interaction : TFIIE and p53 share the binding region on TFIIH.2008

    • Author(s)
      Okuda, M., Tanaka, A., Satoh, M., Mizuta, S., Takazawa, M., Ohkuma, Y., Nishimura, Y.
    • Journal Title

      EMBO J. 27

      Pages: 1161-1171

    • Data Source
      KAKENHI-PROJECT-19770090
  • [Journal Article] 基本転写因子TmEの構造とTFIIHとの相互作用2008

    • Author(s)
      奥田昌彦、西村善文
    • Journal Title

      生化学 80

      Pages: 501-510

    • Data Source
      KAKENHI-PROJECT-19770090
  • [Journal Article] 基本転写因子TFIIEの構造とTFIIHとの相互作用2008

    • Author(s)
      奥田昌彦、西村善文
    • Journal Title

      生化学特集号 80

      Pages: 501-510

    • NAID

      10021192114

    • Data Source
      KAKENHI-PROJECT-19770090
  • [Journal Article] Structural characterization of human general transcription factor TFIIF in solution.2008

    • Author(s)
      Akashi, S., Nagakura, S., Yamamoto, S., Okuda, M., Ohkuma, Y., Nishimura, Y.,
    • Journal Title

      Protein Sci. 17

      Pages: 389-400

    • Data Source
      KAKENHI-PROJECT-19770090
  • [Journal Article] Structural polymorphism of chromodomains in Chd1.2007

    • Author(s)
      Okuda, M., Horikoshi, M., Nishimura, Y.
    • Journal Title

      J Mol Biol. 365

      Pages: 1047-1062

    • Data Source
      KAKENHI-PROJECT-19770090
  • [Presentation] ヒトRNAポリメラーゼと基本転写/修復因子TFIIHの新たな相互作用の構造生物学的研究2022

    • Author(s)
      奥田昌彦, 諏訪哲史, 鈴木秀文, 山口雄輝, 西村善文
    • Organizer
      日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-21K06035
  • [Presentation] RNAポリメラーゼと基本転写/修復因子TFIIHの新たな相互作用2021

    • Author(s)
      奥田昌彦、諏訪哲史、鈴木秀文、山口雄輝、西村善文
    • Organizer
      第39回 染色体ワークショップ・ 第19回 核ダイナミクス研究会
    • Data Source
      KAKENHI-PROJECT-21K06035
  • [Presentation] 本転写因子TFIIEαのイオンモビリティ質量分析2011

    • Author(s)
      奥田昌彦、廣瀬賢治、川瀬泰司、押方基二、西村善文基
    • Organizer
      日本生化学学会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-23570144
  • [Presentation] 基本転写因子TFIIEαのイオンモビリティ質量分析2011

    • Author(s)
      奥田昌彦、廣瀬賢治、川瀬泰司、押方基二、西村善文
    • Organizer
      日本生化学学会
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-23570144
  • [Presentation] Structural analysis for 85 kDa protein complex, general transcription factor TFIIE by NMR spectroscopy2011

    • Author(s)
      Okuda M, Moriwaki Y, Kataoka M, Nagadoi A, Tanaka A, OhkumaY, Nishimura Y.
    • Organizer
      The International Symposium on Nuclear Magnetic Resonance
    • Place of Presentation
      Osanbashi Hall (Yokohama, Japan)
    • Year and Date
      2011-11-16
    • Data Source
      KAKENHI-PROJECT-23570144
  • [Presentation] NMR STRUCTURE OF A GENERAL TRANSCRIPTION FACTOR TFIIE2010

    • Author(s)
      西村善文, 奥田昌彦
    • Organizer
      XXIVth ICMRBS(International Conference on Magnetic Resonance in Biological Systems)
    • Place of Presentation
      ケアンズ、ケアンズコンベンションセンター(オーストラリア)
    • Data Source
      KAKENHI-PROJECT-21770121
  • [Presentation] 基本転写因子TFIIEとそれと相互作用するタンパク質群の機能解析2010

    • Author(s)
      田中亜紀, 水田翔子, 奥田昌彦, 西村善文, 大熊芳明
    • Organizer
      ターゲットタンパク研究プログラム研究交流会
    • Place of Presentation
      東京国際フォーラム(東京都)
    • Year and Date
      2010-03-05
    • Data Source
      KAKENHI-PROJECT-21770121
  • [Presentation] 転写制御因子、ヒストン修飾因子の構造生物学2010

    • Author(s)
      長土居有隆, 奥田昌彦, 明石知子, 西村善文
    • Organizer
      ターゲットタンパク研究プログラム研究交流会
    • Place of Presentation
      東京国際フォーラム(東京都)
    • Year and Date
      2010-03-05
    • Data Source
      KAKENHI-PROJECT-21770121
  • [Presentation] NMR STRUCTURE OF A GENERAL TRANSCRIPTION FACTOR TFIIE2010

    • Author(s)
      Y.Nishimura, M.Okuda
    • Organizer
      XXIVth ICMRBS (International Conference on Magnetic Resonance in Biological Systems)
    • Place of Presentation
      ケアンズコンベンションセンター(オーストラリア・ケアンズ)
    • Year and Date
      2010-08-26
    • Data Source
      KAKENHI-PROJECT-21770121
  • [Presentation] 基本転写因子TFIIEとそれと相互作用するタンパク質群の機能解析2010

    • Author(s)
      田中亜紀, 水田翔子, 奥田昌彦, 西村善文, 大熊芳明
    • Organizer
      ターゲットタンパク研究プログラム基本生命WG班会議
    • Place of Presentation
      新神戸(兵庫県)
    • Data Source
      KAKENHI-PROJECT-21770121
  • [Presentation] 転写制御因子、ピストン修飾因子の構造生物学2010

    • Author(s)
      長土居有隆, 奥田昌彦, 明石知子, 西村善文
    • Organizer
      ターゲットタンパク研究プログラム基本生命WG班会議
    • Place of Presentation
      新神戸(兵庫県)
    • Data Source
      KAKENHI-PROJECT-21770121
  • [Presentation] ヒト基本転写因子TFIIE alpha 酸性ドメインの動的構造解析2009

    • Author(s)
      小松正史, 奥田昌彦, 長土居有隆, 菅瀬謙治, 西村善文
    • Organizer
      第48回NMR討論会
    • Place of Presentation
      九州大学医学部百年講堂(福岡県)
    • Data Source
      KAKENHI-PROJECT-21770121
  • [Presentation] Intrinsically Disordered Transcription related Proteins2009

    • Author(s)
      奥田昌彦, 長土居有隆, 小松正史, 西村善文
    • Organizer
      第3回アジア-太平洋NMRシンポジウム(APNMR)
    • Place of Presentation
      Ramada Plaza Jeju Hotel(韓国)
    • Data Source
      KAKENHI-PROJECT-21770121
  • [Presentation] ヒト基本転写因子TFIIEαの酸性ドメインとヒト基本転写因子TFIIHp62のPHドメインとの複合体の溶液構造2008

    • Author(s)
      奥田昌彦、田中亜紀、佐藤真奈美、水田翔子、高澤学、大熊芳明、西村善文
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      兵庫県神戸市、神戸ポートアイランド
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PROJECT-19770090
  • [Presentation] ヒト基本転写因子TFIIEαの酸性ドメインとヒト基本転写因子TFIIH p62のPHドメインとの複合体の溶液構造2008

    • Author(s)
      奥田昌彦、田中亜紀、佐藤真奈美、水田翔子、高澤学、大熊芳明、西村善文
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      兵庫県神戸市、神戸ポートアイランド
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PROJECT-19770090
  • [Presentation] NMR Studies on the Interaction between the General Transcription Factors2008

    • Author(s)
      Okuda, M., Tanaka, A., Satoh, M., Mizuta, S., Takazawa, M., Ohkuma, Y., Nishimura, Y.
    • Organizer
      TFIIE and TFIIH XXIIIrd ICMRBS Conference
    • Place of Presentation
      米国、カリフォルニア州、サンディエゴ、シェラトンホテル
    • Year and Date
      2008-08-26
    • Data Source
      KAKENHI-PROJECT-19770090
  • [Presentation] NMR Studies on the Interaction between the General Transcription Factors, TFIIE and TFIIH2008

    • Author(s)
      Okuda, M., Tanaka, k, Satoh, M., Mizuta, S., Takazawa, M., Ohkuma, Y., Nishimura, Y.
    • Organizer
      XXIIIrd ICMRBS Conference
    • Place of Presentation
      米国、カリフォルニア州、サンディエゴ、シェラトンホテル
    • Year and Date
      2008-08-26
    • Data Source
      KAKENHI-PROJECT-19770090
  • 1.  西村 善文 (70107390)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  栗田 順一 (90752452)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  下條 優佳 (10728231)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  TSUNAKA Yasuo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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