MINAMI HIRONOBU 南博信

… Alternative Names

MINAMI Hironobu 南博信

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Researcher Number	60450574
Other IDs
Affiliation (Current)	2025: 神戸大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 神戸大学, 医学研究科, 教授 2011 – 2015: 神戸大学, 医学(系)研究科(研究院), 教授 2010: 神戸大学, 医学部・付属病院, 教授 2008 – 2010: 神戸大学, 医学部附属病院, 教授
Review Section/Research Field	Principal Investigator Applied pharmacology / Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Medical pharmacy
Keywords	Principal Investigator 免疫チェックポイント阻害薬 / 免疫関連有害事象 / がん / HLA / 臨床薬理学 / 乳癌 / 乳がん / BCR / irAE / 網羅型タンパク質アレイ … More / 無細胞タンパク質合成系による抗体作成 / B細胞受容体レパトア解析 / 抗体 / B細胞 / 免疫チェックポイント / バイオマーカー / 免疫チャックポイント阻害薬 / マイマーカー / 免疫チェックポイント阻害 / 腫瘍内科学 / PDX / Tyro3 / 肺がん / Gas6 / TYRO3 / 肺癌 / プロテオーム / パクリタキセル / プロテオーム解析 / 抗腫瘍効果 / 末梢神経毒性 / 化学療法 … More Except Principal Investigator T細胞 / PD-1 / 免疫シナプス / Ｔ細胞 / CD28 / 胃癌 / 適正使用 / 代謝拮抗剤 / フッ化ピリミジン系 / がん化学療法 / 大腸癌 Less

B細胞を軸とした免疫チェックポイント阻害の有害事象の包括的機序解明と効果の推定Principal Investigator
- Principal Investigator
  
  南博信
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kobe University
Investigating whether antibody production contributes to immune-related adverse events using an acellular protein synthesis systemPrincipal Investigator
- Principal Investigator
  
  Minami Hironobu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kobe University
Identification of responder of gastric cancer patients for anti-PD-1 antibody therapy by quantification the capacity of CD28 molecules on the surface of T cells.
- Principal Investigator
  
  Kakeji Yoshihiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kobe University
HLA as a biomarker for Immune checkpoint inhibitosPrincipal Investigator
- Principal Investigator
  
  Minami Hironobu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kobe University
Evaluation of TYRO3 as a therapeutic target in breast and lung cancersPrincipal Investigator
- Principal Investigator
  
  Minami Hironobu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kobe University
Establishment of the optimal administration method for anticancer agents by proteomics and metabolomicsPrincipal Investigator
- Principal Investigator
  
  MINAMI Hironobu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kobe University
Appropriate use of the oral fluoropyrimidine anticancer drugs in patients with colorectal cancer
- Principal Investigator
  
  NISHIGUCHI Kohshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto Pharmaceutical University

All 2023 2022 2021 2019 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Transition of the PD?1 occupancy of nivolumab on T cells after discontinuation and response of nivolumab re?challenge2022
- Author(s)
  Nose Taku、Funakoshi Yohei、Suto Hirotaka、Nagatani Yoshiaki、Imamura Yoshinori、Toyoda Masanori、Kiyota Naomi、Minami Hironobu
- Journal Title
  
  Molecular and Clinical Oncology
  
  Volume: 16 Issue: 5
- DOI
  10.3892/mco.2022.2537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07676, KAKENHI-PROJECT-20K09731
[Journal Article] Safety and efficacy of nivolumab plus bevacizumab, paclitaxel for HER2-negative metastatic breast cancer: Primary results and biomarker data from a phase 2 trial (WJOG9917B)2022
- Author(s)
  Ozaki Yukinori、Tsurutani Junji、Mukohara Toru、Iwasa Tsutomu、Takahashi Masato、Tanabe Yuko、Kawabata Hidetaka、Masuda Norikazu、Futamura Manabu、Minami Hironobu、Matsumoto Koji、Yoshimura Kenichi、Kitano Shigehisa、Takano Toshimi
- Journal Title
  
  European Journal of Cancer
  
  Volume: 171 Pages: 193-202
- DOI
  10.1016/j.ejca.2022.05.014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07216, KAKENHI-PROJECT-20K07676
[Journal Article] Open-label phase II study of the efficacy of nivolumab for cancer of unknown primary2022
- Author(s)
  J. Tanizaki, K. Yonemori, K. Akiyoshi, H. Minami, H. Ueda, Y. Takiguchi, et al.
- Journal Title
  
  Annals of Oncology
  
  Volume: 33 Issue: 2 Pages: 216-226
- DOI
  10.1016/j.annonc.2021.11.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08561, KAKENHI-PROJECT-20K07676
[Journal Article] Serum Soluble Interleukin-2 Receptor as a Potential Biomarker for Immune-related Adverse Events2021
- Author(s)
  TAKAI RYO、FUNAKOSHI YOHEI、SUTO HIROTAKA、NAGATANI YOSHIAKI、IMAMURA YOSHINORI、TOYODA MASANORI、YAKUSHIJIN KIMIKAZU、KIYOTA NAOMI、HARADA KEN-ICHI、YAMASHITA KIMIHIRO、KAKEJI YOSHIHIRO、MINAMI HIRONOBU
- Journal Title
  
  Anticancer Research
  
  Volume: 41 Issue: 2 Pages: 1021-1026
- DOI
  10.21873/anticanres.14857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19580
[Journal Article] Long-term follow up of nivolumab in previously untreated Japanese patients with advanced or recurrent malignant melanoma.2019
- Author(s)
  Yamazaki N, Kiyohara Y, Uhara H, Uehara J, Fujisawa Y, Takenouchi T, Otsuka M, Uchi H, Ihn H, Hatsumichi M, Minami H.
- Journal Title
  
  Cancer Sci
  
  Volume: 110 Issue: 6 Pages: 1995-2003
- DOI
  10.1111/cas.14015
- NAID
  120006653247
- Data Source
  KAKENHI-PROJECT-17K08952
[Journal Article] Efficacy and safety of nivolumab in Japanese patients with uterine cervical cancer, uterine corpus cancer, or soft tissue sarcoma: multicenter, opemn-label phase 2 trial2019
- Author(s)
  Tamura K, Hasegawa K, Katsumata N, Matsumoto K, Mukai H, Takahashi S, Nomura H, Minami H.
- Journal Title
  
  Cancer Sci
  
  Volume: 110 Issue: 9 Pages: 2894-2904
- DOI
  10.1111/cas.14148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08952
[Journal Article] Efficacy and safety of nivolumab in Japanese patients with previously untreated advanced melanoma: A phase II study2017
- Author(s)
  Yamazaki Naoya、Kiyohara Yoshio、Uhara Hisashi、Uehara Jiro、Fujimoto Manabu、Takenouchi Tatsuya、Otsuka Masaki、Uchi Hiroshi、Ihn Hironobu、Minami Hironobu
- Journal Title
  
  Cancer Sci
  
  Volume: 108 Issue: 6 Pages: 1223-1230
- DOI
  10.1111/cas.13241
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10165, KAKENHI-PROJECT-17K08952
[Journal Article] Expression of programmed death-1 in sentinel lymph nodes of breast cancer.2017
- Author(s)
  Tatara T, Mukohara T, Shimono Y, Yamasaki T, Imamura Y, Funakoshi Y, Toyoda M, Kiyota N, Takao S, Kono S, Kakeji Y, Minami H
- Journal Title
  
  J Surg Oncol.
  
  Volume: Epub ahead of print Issue: 6 Pages: 2017-2017
- DOI
  10.1002/jso.24937
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10541, KAKENHI-PROJECT-17K08952, KAKENHI-PROJECT-16H05415
[Journal Article] The comobination of HLA-B*15:01 and DRB1*15:01 is associated with gemcitabine plus erlotinib-induced interstitial lung disease in pateints with advanced pancreatic cancer.2016
- Author(s)
  Nishimura M, Toyoda M, Tkenaka K, Imamura Y, Chayahara N, Kiyota N, Mukohara T, Kotake T, Tsuji A, Saito K, Saito Y, Minami H.
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 77 Issue: 6 Pages: 1165-1171
- DOI
  10.1007/s00280-016-3026-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460627
[Journal Article] A prospective study of the antiemetic effect of palonosetron in malignant lymphoma patients treated with the CHOP regimen.2016
- Author(s)
  Miyata Y, Yakushijin K, Inui Y, Imamura Y, Goto H, Mizutani Y, Kurata K, Kakiuchi S, Sanada Y, Minami Y, Kawamoto S, Yamamoto K, Ito M, Tominaga R, Gomyo H, Mizuno I, Nomura T, Kitagawa K, Sugimoto T, Murayama T, Matsuoka H, Minami H.
- Journal Title
  
  Int J Hematol
  
  Volume: 104 Issue: 6 Pages: 682-691
- DOI
  10.1007/s12185-016-2089-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460627, KAKENHI-PROJECT-26460677
[Journal Article] Validity of new methods to evaluate renal function in cancer patients treated with cisplatin.2016
- Author(s)
  Funakoshi Y, Fujiwara Y, Kiyota N, Mukohara T, Shimada T, Toyoda M, Imamura Y, Chayahara N, Tomioka H, Umezu M, Otsuki N, Nibu K, Minami H
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 77 Issue: 2 Pages: 281-288
- DOI
  10.1007/s00280-016-2966-1
- Data Source
  KAKENHI-PROJECT-26460627
[Journal Article] A sensitive cytometry based system for enumeration, capture and analysis of gene mutations of circulating tumor cells.2016
- Author(s)
  Sawada T, Watanabe M, Fujimura Y, Yagishita S, Yashita S, Shimoyama T, Maeda Y, Kanda S, Yunokawa M, Tamura K, Tamura T, Minami H, Koh Y, Koizumi F.
- Journal Title
  
  Cancer Sci
  
  Volume: 107 Issue: 3 Pages: 307-314
- DOI
  10.1111/cas.12868
- Data Source
  KAKENHI-PROJECT-26460627
[Journal Article] A phase 1, multicenter, open-label, 2-group, parallel, dose-escalation study of oral sonidegib in Asian patients with advanced solid tumors.2016
- Author(s)
  Minami H, Ando Y, Ma BBY, Lee J-H, Momota H, Fujiwara Y, Li L, Fukino K, Ito K, Tajima T, Mori A, Lin C-C.
- Journal Title
  
  Cancer Science
  
  Volume: 107 Issue: 10 Pages: 1477-1483
- DOI
  10.1111/cas.13022
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460627
[Journal Article] Comparison of 2D- and 3D-culture models as drug-testing platforms in breast cancer2015
- Author(s)
  Imamura Y, Mukohara T, Shimono Y, Funakoshi Y, Chayahara N, Toyoda M, Kiyota N, Takao S, Kono S, Nakatsura T, Minami H
- Journal Title
  
  Oncol Rep
  
  Volume: 33 Issue: 4 Pages: 1837-1843
- DOI
  10.3892/or.2015.3767
- NAID
  120005758024
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23501268, KAKENHI-PUBLICLY-25130707, KAKENHI-PROJECT-15K08588, KAKENHI-PROJECT-26460627, KAKENHI-PROJECT-15K14381
[Journal Article] MicroRNA regulation of human breast cancer stem cells2015
- Author(s)
  194.Shimono Y, Mukoyama J, Nakamura S, Minami H.
- Journal Title
  
  J Clin Med
  
  Volume: 5 Issue: 1 Pages: 2-2
- DOI
  10.3390/jcm5010002
- NAID
  120005697222
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460627, KAKENHI-PROJECT-15K14381, KAKENHI-PROJECT-15K15066
[Journal Article] Barriers and challenges to global clinical cancer research2014
- Author(s)
  Seruga B, Sadikov A, Cazap EL, Delgado LB, Digumarti R, Leighl NB, Meshref MM, Minami H, Robinson E, Yamaguchi NH, Pyle D, Cufer T
- Journal Title
  
  Oncologist
  
  Volume: 19(1) Pages: 61-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590640
[Journal Article] TYRO3 as a potential therapeutic target in breast cancer.2014
- Author(s)
  Ekyalongo RC, Mukohara T, Funakoshi Y, Tomioka H, Kataoka Y, Shimono Y, Chayahara n, Toyada M, Kiyota N, Minami H
- Journal Title
  
  Anticancer Res
  
  Volume: 34 Pages: 3337-45
- Data Source
  KAKENHI-PROJECT-26460627
[Journal Article] Pathologic complete response after neoadjuvant chemotherapy in HER2-overexperssing breast cancer according to hormonal receptor status2014
- Author(s)
  Tanioka M, Sasaki M, Shimomura A, Fujishima M, Doi M, Matsuura K, Sakuma T, Yoshimura K, Saeki T, Ohara M, Tsurutani J, Watatani M, Takano T, Kawabata H, Mukai H, Naito Y, Hirokaga K, Takao S, Minami H
- Journal Title
  
  Breast(Epub)
  
  Volume: 23 Issue: 4 Pages: 466-472
- DOI
  10.1016/j.breast.2014.03.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590640
[Journal Article] A novel serum metabolomics-based diagnostic approach to pancreatic cancer.2013
- Author(s)
  Kobayashi T, Nishiumi S, Ikeda A, Yoshie T, Sakai A, Matsubara A, Izumi Y, Tsumura H, Tsuda M, Nishisaki H, Hayashi N, Kawano S, Fujiwara Y, Minami H, Takenawa T, Azuma T, Yoshida M.
- Journal Title
  
  Cancer Epidemiology Biomarkers & Prevention
  
  Volume: 22 Pages: 571-579
- Data Source
  KAKENHI-PROJECT-23590640
[Journal Article] Mechanisms of acquired resistance to insulin-like growth factor 1 receptor inhibitor in MCF-7 breast cancer cell line.2013
- Author(s)
  Ekylongo RC, Mukohara T, Kataoka Y, Kiyota N, Fujiwara Y, Minami H.
- Journal Title
  
  Invest New Drugs
  
  Volume: 31 Pages: 293-303
- Data Source
  KAKENHI-PROJECT-23590640
[Journal Article] A novel serum metabolomics-based diagnostic approach to pancreatic cancer2013
- Author(s)
  Kobayashi T, Nishiumi S, Ikeda A, Yoshie T, Sakai A, Matsubara A, Izumi Y, Tsumura H, Tsuda M, Nishisaki H, Hayashi N, Kawano S, Fujiwara Y, Minami H, Takenawa T, Azuma T, Yoshida M
- Journal Title
  
  Cancer Epidemiology Biomarkers & Prevention
  
  Volume: 22 Pages: 571-579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590640
[Journal Article] Mechanisms of acquired resistance to insulin-like growth factor 1 receptor inhibitor in MCF-7 breast cancer cell line2013
- Author(s)
  Ekylongo RC, Mukohara T, Kataoka Y, Kiyota N, Fujiwara Y, Minami H
- Journal Title
  
  Invest New Drugs
  
  Volume: 31 Pages: 293-303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590640
[Journal Article] Excessive MET signaling causes acquired resistance and addiction to MET inhibitors in the MKN45 gastric cancer cell line2013
- Author(s)
  Funakoshi Y, Mukohara T, Tomioka H, Ekyalongo RC, Kataoka Y, Inui Y, Kawamori Y, Toyoda M, Kiyota N, Fujiwara Y, Minami H
- Journal Title
  
  Invest New Drugs
  
  Volume: 31 (5) Pages: 1158-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590640
[Journal Article] Inhibition of the mTOR/S6K signal is necessary to enhance fluorouracil-induced apoptosis in gastric cancer cells with HER2 amplification2012
- Author(s)
  Tomioka H, Mukohara T, Kataoka Y, Ekyalongo RC, Funakoshi Y, Imai Y, Kiyota N, Fujiwara Y, Minami H
- Journal Title
  
  Int J Oncol
  
  Volume: 41 Pages: 551-558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590640
[Journal Article] Eribulin mesylate in patients with refractory cancers:a phase I study2012
- Author(s)
  Mukohara T, Nagai S, Mukai H, Namiki M, Minami H.
- Journal Title
  
  Invest New Drugs
  
  Volume: 30 (5) Pages: 1926-1933
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590640
[Journal Article] Foretinib (GSK1363089), a multi-kinase inhibitor of MET and VEGFRs, inhibits growth of gastric cancer cell lines by blocking inter-receptor tyrosine kinase networks2012
- Author(s)
  Kataoka Y, Mukohara T, Tomioka H, Funakoshi Y, Kiyota N, Fujiwara Y, Yashiro M, Hirakawa K, Hirai M, Minami H
- Journal Title
  
  Invest New Drugs
  
  Volume: 30 (4) Pages: 1352-1360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590640
[Presentation] A Phase II Trial of Nivolumab for Patients with Platinum Refractory Recurrent or Metastatic Salivary Gland Cancer2023
- Author(s)
  Nagatani Y, Kiyota N, Yamazaki T, Asada Y, Higashino M, Goto M, Satake H, Ota I, Uemura H, Yane K, Tanaka K, Onoe T, Iwae S, Hirano S, Imamura Y, Kimbara S, Nose T, Koyama T, Funakoshi Y, Minami H
- Organizer
  Am Soc Clin Oncol
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27457
[Presentation] Tumor immune microenvironment in salivary gland cancer2022
- Author(s)
  Nagatani Y, Kiyota N, Imamura Y, Koyama T, Funakoshi Y, Komatsu M, Teshima M, Nibu K, Sakai K, Nishio K, Shimomura M, Nakatsura T, Ikarashi D, Nakayama T, Kitano S, Minami H
- Organizer
  Assoc Am Cancer Res
- Data Source
  KAKENHI-PROJECT-20K07676
[Presentation] Quantitative mass spectrometry imaging of erlotinib in skin rashed of cancer patients receiving erlotinib2017
- Author(s)
  114. Nishimura M, Aikawa H, Hayashi M, Mizutani Y, Takenaka K, Imamura Y, Chayahara N, Toyoda M, Kiyota N, Mukohara T, Hamada A, Minami H.
- Organizer
  American Association for Cancer Research
- Place of Presentation
  Washington DC (USA)
- Year and Date
  2017-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460627
[Presentation] 3D culture may better represent trastuzumab resistance associated with PIK3CA mutation than 2D culture.2017
- Author(s)
  115. Tatara T, Mukohara T, Tanaka R, Shimono Y, Toyoda M, Kiyota N, Hirai M, Kakeji Y, Minami H.
- Organizer
  American Association for Cancer Research
- Place of Presentation
  Washington DC
- Year and Date
  2017-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460627
[Presentation] MicroRNA-7 suppresses RB1 expression leading to chromosomal instability in leukemia cells harboring c-Kit mutation.2017
- Author(s)
  112. Kurata K, Kawamoto S, Masutani R, Yakushijin K, Yamamoto K, Matsuoka H, Takubo T, Minami H.
- Organizer
  American Association for Cancer Research
- Place of Presentation
  Washington DC (USA)
- Year and Date
  2017-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460627
[Presentation] MicroRNA-mediated upregulation of the WNT signaling activities in human breast cancer stem cells2017
- Author(s)
  113. Shimono Y, Isobe T, Turtoi A, Mukohyama J, Mukohara T, Suzuki A, Castronovo V, Minami H.
- Organizer
  American Association for Cancer Research
- Place of Presentation
  Washington DC (USA)
- Year and Date
  2017-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460627
[Presentation] Comparison of 2D- and 3D-culture models as drug-testing platforms in breast cancer2015
- Author(s)
  107. Imamura Y, Mukohara T, Shimono Y, Funakoshi Y, Chayahara N, Toyoda M, Kiyota N, Takao S, Kono S, Nakatsura T, Minami H
- Organizer
  Am Assoc Cancer Res
- Place of Presentation
  Philadelphia
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460627
[Presentation] 乳癌における新規治療標的としてのTyro32013
- Author(s)
  Ekylongo Roudy Chiminch、向原徹、船越洋平、富岡秀夫、片岡優、豊田昌徳、清田尚臣、南博信
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590640
[Presentation] HER2陽性ホルモン受容体陽性(HR+)乳癌における術前科学療法後病理学的完全寛解(pCR)の臨床的意義2013
- Author(s)
  谷岡真樹、佐々木正興、下村昭彦、藤島茂、土井美帆子、松浦一生、吉村健一、内藤陽一、高尾信太郎、南博信
- Organizer
  第11回日本臨床腫瘍学会学術集会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590640
[Presentation] Excessive MET signaling causes acquired resistance to and addiction to METinhibitors MET-amplifed cancer cellline2013
- Author(s)
  船越洋平、向原徹、富岡秀夫、Ekylongo Roudy Chiminch、片岡優、豊田昌徳、清田尚美、藤原豊、南博信
- Organizer
  第11回日本臨床腫瘍学会学術集会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590640
[Presentation] Pathologic complete response to cisplatin with dose-dense paclitaxel as neoadjuvant chemotherapy for locally advanced cervical cancer: Preliminary results of a multicenter phase II study with additional mutation analysis of adeno/adenosquamous carcinoma.2013
- Author(s)
  Tanioka M, Yamaguchi S, Sato S, Nagao S, Takehara K, Nishimura M, Sudo T, Morita S, Minami H, Negoro S, Shimada M, Kigawa J, Fujiwara K.
- Organizer
  Am Soc Clin Oncol
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-23590640
[Presentation] Excessive MET signaling causes acquired resistance to and addiction to MET inhibitors in MKN45 gastric cancer cell line2012
- Author(s)
  Funakoshi Y, Mukohara T, Tomioka H, Ekyalonog RC, Kataoka Y, Inui Y, Kawamori Y, Kiyota N, Fujiwara Y, Minami H
- Organizer
  24rh EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics
- Place of Presentation
  Dublin, Ireland
- Data Source
  KAKENHI-PROJECT-23590640
[Presentation] MCF-7乳癌細胞株におけるinsuylin-like growth factor 1 receptor受容体阻害薬に対する獲得耐性機構2012
- Author(s)
  Ekylongo Roudy Chiminch、向原徹、片岡優、船越洋平、富岡秀夫、清田尚臣、藤原豊、南博信
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590640
[Presentation] Comparison of 2D- and 3D-culture models as drug-testing platforms in breast cancer
- Author(s)
  Yoshinori Imamura, Toru Mukohara, Yohei Shimono, Yohei Funakoshi, Naoko Chayahara, Masanori Toyoda, Naomi Kiyota, Shintaro Takao, Seishi Kono, Tetsuya Nakatsura, and Hironobu Minami
- Organizer
  AACR Annual Meeting 2015
- Place of Presentation
  Philadelphia
- Year and Date
  2015-04-17 – 2015-04-20
- Data Source
  KAKENHI-PROJECT-26460627
[Presentation] Clinicopathological Analysis of Salivary Duct Carcinoma and Salivary Gland Adenocarcinoma
- Author(s)
  今村善宣、清田尚臣、大月直樹、平井千穂子、伊藤智雄、船越洋平、佐々木良平、丹生健一、向原徹、南博信
- Organizer
  第12回日本臨床腫瘍学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2014-07-17 – 2014-07-19
- Data Source
  KAKENHI-PROJECT-26460627

1. 船越洋平 (50566966)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
2. NISHIGUCHI Kohshi (80379437)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. SAKAEDA Toshiyuki (00304098)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. HIRAI Midori (70228766)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TAMURA Takao (80324929)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YAMAMORI Motohiro (10444613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MUKOUHARA Toru (80435718)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
8. YOSHIDA Masaru (00419475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. Kakeji Yoshihiro (80284488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 高尾信太郎 (10717218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 伊藤智雄 (20301880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. 眞庭謙昌 (50362778)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 山下公大 (80535427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 坂本明美 (90359597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 清田尚臣 (40515037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. TAKIGUCHI Yuuichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 下野洋平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 尹浩信

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 鶴谷純司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MINAMI HIRONOBU 南 博信

MINAMI Hironobu 南 博信

Research Projects

Research Products

Co-Researchers

B細胞を軸とした免疫チェックポイント阻害の有害事象の包括的機序解明と効果の推定Principal Investigator

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Investigating whether antibody production contributes to immune-related adverse events using an acellular protein synthesis systemPrincipal Investigator

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Identification of responder of gastric cancer patients for anti-PD-1 antibody therapy by quantification the capacity of CD28 molecules on the surface of T cells.

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HLA as a biomarker for Immune checkpoint inhibitosPrincipal Investigator

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Evaluation of TYRO3 as a therapeutic target in breast and lung cancersPrincipal Investigator

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Establishment of the optimal administration method for anticancer agents by proteomics and metabolomicsPrincipal Investigator

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Appropriate use of the oral fluoropyrimidine anticancer drugs in patients with colorectal cancer

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[Journal Article] Transition of the PD?1 occupancy of nivolumab on T cells after discontinuation and response of nivolumab re?challenge2022

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[Journal Article] Safety and efficacy of nivolumab plus bevacizumab, paclitaxel for HER2-negative metastatic breast cancer: Primary results and biomarker data from a phase 2 trial (WJOG9917B)2022

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[Journal Article] Open-label phase II study of the efficacy of nivolumab for cancer of unknown primary2022

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[Journal Article] Serum Soluble Interleukin-2 Receptor as a Potential Biomarker for Immune-related Adverse Events2021

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[Journal Article] Long-term follow up of nivolumab in previously untreated Japanese patients with advanced or recurrent malignant melanoma.2019

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[Journal Article] Efficacy and safety of nivolumab in Japanese patients with uterine cervical cancer, uterine corpus cancer, or soft tissue sarcoma: multicenter, opemn-label phase 2 trial2019

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[Journal Article] Efficacy and safety of nivolumab in Japanese patients with previously untreated advanced melanoma: A phase II study2017

Author(s)

MINAMI HIRONOBU 南博信

MINAMI Hironobu 南博信

[Journal Article] The comobination of HLA-B15:01 and DRB115:01 is associated with gemcitabine plus erlotinib-induced interstitial lung disease in pateints with advanced pancreatic cancer.2016