YAGI Masanori 八木正典

Researcher Number	60452463
Other IDs
Affiliation (based on the past Project Information) *help	2015: 大阪大学, 微生物病研究所, 特任研究員 2014: 大阪大学, 微生物病研究所, 特任研究員(常勤) 2008 – 2012: 大阪大学, 微生物病研究所, 特任研究員 2010: 大阪大学, 微生物病研究所, 特任研究員(常勤)
Review Section/Research Field	Principal Investigator Biophysics Except Principal Investigator Parasitology (including Sanitary zoology) / Evolutionary biology / Biological Sciences
Keywords	Principal Investigator タンパク質の構造安定性 / 熱帯熱マラリア / SE36 / 構造物性 / ワクチン / マラリア / マラリアワクチン / タンパク質の物性 Except Principal Investigator 遺伝子多型 / SERA … More / マラリア / IGGサブクラス / IgGサブクラス / 臨床試験 / ワクチン / 遺伝子アァミリー / 多様性 / 宿主 / 遺伝子ファミリー / マラリア原虫 / 遺伝子組換え / 遺伝子組み換え / マイクロサテライト / 組み換え / 流行度 / 多重感染 / 三日熱マラリア原虫 / SE36 マラリアワクチン / 多重族遺伝子群 / SE36マラリアワクチン / 多重遺伝子群 / Plasmodium Less

Basic research of BK-SE36 malaria vaccine clinical study
- Principal Investigator
  
  Horii Toshihiro
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Osaka University
Structural analysis of Plasmodium falciparummalaria vaccine candidate antigen SERA5Principal Investigator
- Principal Investigator
  
  YAGI Masanori
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Osaka University
The diversity of Plasmodium SERA gene family : Adaptation of parasitism and host range
- Principal Investigator
  
  ARISUE Nobuko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Evolutionary biology
- Research Institution
  Osaka University
How P.vivax parasite maintains multiple infection in areas of low intensity malaria?
- Principal Investigator
  
  HORII Toshihiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Osaka University
Malaria genetic diversity as a basis for parasite growth and pathogenicity
- Principal Investigator
  
  HORII Toshihiro
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University

All 2014 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] Protective epitopes of the Plasmodium falciparum SERA5 malaria vaccine reside in intrinsically unstructured N-terminal repetitive sequences.2014
- Author(s)
  Yagi M, Bang G, Tougan T, Palacpac NM, Arisue N, Aoshi T, Matsumoto Y, Ishii KJ, Egwang TG, Druilhe P, Horii T.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 6 Pages: e98460-e98460
- DOI
  10.1371/journal.pone.0098460
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23256001, KAKENHI-PROJECT-24249024
[Journal Article] Endemic Burkitt lymphoma is associated with strength and diversity of Plasmodium falciparummalaria stage-specific antigen antibody response2013
- Author(s)
  Aka P, Vila MC, Jariwala A, Nkrumah F, Emmanuel B, Yagi M, Palacpac NM, Periago MV, Neequaye J, Kiruthu C, Tougan T, Levine PH, Biggar RJ, Pfeiffer RM, Bhatia K, Horii T, Bethony JM, Mbulaiteye SM
- Journal Title
  
  Blood
  
  Volume: 122(5) Issue: 5 Pages: 629-635
- DOI
  10.1182/blood-2012-12-475665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700455, KAKENHI-PROJECT-24249024
[Journal Article] Phase 1b randomized trial and follow-up study in Uganda of the blood-stage malaria vaccine candidate BK-SE36.2013
- Author(s)
  Palacpac N.M.Q., Ntege E., Yeka A. Balikagala B., Suzuki N., Shirai H., Yagi M., Ito K., Fukushima W., Hirota Y., Nsereko C., Okada T., Kanoi B.N., Tetsutani K., Arisue N., Itagak S., Tougan T., Ishii K.J., Ueda S., Egwang T.G., and Horii T.
- Journal Title
  
  PLoS ONE.
  
  Volume: 8(5) Issue: 5 Pages: e64073-e64073
- DOI
  10.1371/journal.pone.0064073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249024
[Journal Article] Lipocalin 2 bolsters innate and adaptive immune responses to blood-stage malaria infection by reinforcing host iron metabolism.2012
- Author(s)
  Hong Zhao
- Journal Title
  
  Cell Host & Microbe
  
  Volume: 12 Issue: 5 Pages: 705-716
- DOI
  10.1016/j.chom.2012.10.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659199, KAKENHI-PROJECT-24249024
[Journal Article] Geographic differentiation of polymorphismin the Plasmodium falciparum malariavaccine candidate gene SERA52012
- Author(s)
  Kazuyuki Tanabe, Nobuko Arisue, NirianneM. Q. Palacpac, Masanori Yagi, TakahiroTougan, Hajime Honma, Marcelo U. Ferreira, Anna Farnert, Anders Bjorkman, Akira Kaneko, Masatoshi Nakamura, KenjiHirayama, Toshihiro Mita, Toshihiro Horii
- Journal Title
  
  Vaccine
  
  Volume: 30 Pages: 1583-1593
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570238
[Journal Article] Geographic differentiation of polymorphism in the Plasmodium falciparum malaria vaccine candidate gene SERA52012
- Author(s)
  Tanabe K, Arisue N, 他12名
- Journal Title
  
  Vaccine
  
  Volume: 30 Issue: 9 Pages: 1583-1593
- DOI
  10.1016/j.vaccine.2011.12.124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570238, KAKENHI-PROJECT-22406012, KAKENHI-PROJECT-22700455, KAKENHI-PROJECT-22770151, KAKENHI-PROJECT-23590498, KAKENHI-PROJECT-23659211
[Journal Article] Serologic markers in relation to parasiteexposure history help to estimatetransmission dynamics of Plasmodium vivax2011
- Author(s)
  Fadile Yildiz Zeyrek, Nirianne Palacpac, Fehmi Yuksel, Masanori Yagi, Kaori Honjo, Yukiko Fujita, Nobuko Arisue, Satoru Takeo, Kazuyuki Tanabe, Toshihiro Horii, TakafumiTsuboi, Ken J. Ishii, Cevayir Coban
- Journal Title
  
  PLoS One
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570238
[Journal Article] The Malarial Metabolite Hemozoin and Its Potential Use as a Vaccine Adjuvant2010
- Author(s)
  Yagi M, Horii T K, et al.
- Journal Title
  
  Allergol Int.
  
  Volume: 59(2) Pages: 115-24
- NAID
  10029669847
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18073013
[Journal Article] Immunogenicity of Whole-Parasite Vaccines against Plasmodium falciparum Involves Malarial Hemozoin and Host TLR9.2010
- Author(s)
  Coban C, Igari Y, Yagi M, Reimer T, Koyama S, Aoshi T, Ohata K, Tsukui T, Takeshita F, Sakurai K, Ikegami T, Nakagawa A, Horii T, Nunez G, Ishii KJ, Akira S.
- Journal Title
  
  Cell Host Microbe. 21(7)
  
  Pages: 50-61
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18073013
[Journal Article] The Malarial Metabolite Hemozoin and Its Potential Use as a Vaccine Adjuvant2010
- Author(s)
  Coban C, Yagi M, Ohata K, Igari Y, Tsukui T, Horii T, Ishii KJ, Akira S
- Journal Title
  
  Allergol Int.
  
  Volume: 59(2) Pages: 115-124
- NAID
  10029669847
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18073013
[Presentation] マラリアワクチンBK-SE36に対する抗体応答と感染・発症防御効果の解析2014
- Author(s)
  八木正典、Nirianne M. Q. Palacpac、東岸任弘、伊藤一弥、Betty Balikagala、Edward Ntege、Adoke Yeka、Bernard N. Kanoi、Osbert Katuro、白井宏樹、福島若葉、廣田良夫、Thomas G. Egwang、堀井俊宏
- Organizer
  第83回日本寄生虫学会大会
- Place of Presentation
  松山市
- Data Source
  KAKENHI-PROJECT-24249024
[Presentation] SE36 マラリアワクチン抗原遺伝子sera5の多型解析2013
- Author(s)
  有末伸子, Nirianne M. Q. Palacpac, 八木正典, 東岸任弘, Betty Balikagala, Adoke Yeka, Edward Ntege, Bernard Kanoi, Katuro Osbert, Tom Egwang, 堀井俊宏
- Organizer
  第11回分子寄生虫マラリア研究フォーラム
- Place of Presentation
  長崎市
- Data Source
  KAKENHI-PROJECT-24249024
[Presentation] 抗SE36抗体の誘導とマラリア抵抗性に関与する遺伝的バックグラウンドの研究2013
- Author(s)
  東岸任弘、Nirianne Q. Palacpac、八木正典、中村昇太、後藤和義、Thomas G. Egwang、堀井俊宏
- Organizer
  感染症若手フォーラム 2013
- Place of Presentation
  北海道北広島市/日本
- Data Source
  KAKENHI-PROJECT-24249024
[Presentation] Development of SE36 malaria vaccine 2: Phase1b clinical trial and follow-up research in Uganda for BK-SE36 malaria vaccine2013
- Author(s)
  Nirianne Q. Palacpac, Takahiro Tougan, Masanori Yagi, Thomas G Egwang and Toshihiro HoriiNirianne Q. Palacpac, Takahiro Tougan, Masanori Yagi, Thomas G Egwang and Toshihiro Horii
- Organizer
  Forum Cheju 16
- Place of Presentation
  ソウル
- Data Source
  KAKENHI-PROJECT-24249024
[Presentation] ウガンダにおけるマラリアワクチンBK-SE36第Ib相臨床試験での抗体応答と自然感染後のブースト効果についての解析2013
- Author(s)
  八木正典、Nirianne M. Q. Palacpac、白井宏樹、有末伸子、板垣佐和子、東岸任弘、石井健、Thomas G. Egwang、堀井俊宏
- Organizer
  感染症若手フォーラム2013
- Place of Presentation
  北海道北広島市／日本
- Data Source
  KAKENHI-PROJECT-24249024
[Presentation] African HLA genes in a population that participated in the Phase 1b trial of BK-SE362013
- Author(s)
  Takahiro Tougan, Nirianne Q. Palacpac, Masanori Yagi, Thomas G Egwang and Toshihiro Horii
- Organizer
  The 12th Awaji International Forum on Infection and Immunity
- Place of Presentation
  淡路市
- Data Source
  KAKENHI-PROJECT-24249024
[Presentation] Development of SE36 malaria vaccine 3: Immunogenicity of SE36 and boosting effect following natural infection2013
- Author(s)
  Masanori YAGI, Nirianne M. Q. PALACPAC, Takahiro TOUGAN,Nobuko ARISUE, Toshihiro HORII
- Organizer
  Forum Cheju-16
- Place of Presentation
  ソウル
- Data Source
  KAKENHI-PROJECT-24249024
[Presentation] A blood-stage vaccine clinical trial and follow-up study in Uganda: The promise of BK-SE362013
- Author(s)
  Nirianne Marie Q. Palacpac, Edward Ntege, Betty Balikagala, Adoke Yeka, Nahoko Suzuki, Hiroki Shirai, Kazuya Ito, Masanori Yagi, Christopher Nsereko, Bernard Kanoi, Takuya Okada, Kohhei Tetsutani, Wakaba Fukushima, Yoshio Hirota, Nobuko Arisue, Sawako Itagaki and Toshihiro Horii
- Organizer
  The 12th Awaji International Forum on Infection and Immunity
- Place of Presentation
  淡路市
- Data Source
  KAKENHI-PROJECT-24249024
[Presentation] 抗SE36抗体の誘導とマラリア抵抗性に関与する遺伝的バックグラウンドの研究2013
- Author(s)
  東岸任弘、ニリアン・Q・パラックパック、八木正典、中村昇太、後藤和義、トーマス・G・エグワン、堀井俊宏
- Organizer
  第82回日本寄生虫学会大会
- Place of Presentation
  東京都文京区/日本
- Data Source
  KAKENHI-PROJECT-24249024
[Presentation] Polymorphism of the Plasmodium falciparum sera5 gene.2013
- Author(s)
  Nobuko ARISUE, Nirianne M. Q. PALACPAC, Masanori YAGI, Takahiro TOUGAN, Betty BALIKAGALA, Adoke YEKA, Edward NTEGE, Bernard KANOI, Katuro OSBERT, Tom EGWANG, Toshihiro HORII
- Organizer
  Forum Cheju-16
- Place of Presentation
  ソウル
- Data Source
  KAKENHI-PROJECT-24249024
[Presentation] N-terminal repetitive sequences of Plasmodium falciparum SERA5 are malaria protective epitopes with an intrinsically unstructured nature in Ugandan adults2013
- Author(s)
  Masanori Yagi, Gilles Bang, Nobuko Arisue, Takahiro Tougan, Nirianne M.Q. Palacpac, Taiki Aoshi, Ken J. Ishii, Thomas G. Egwang, Pierre Druilhe, Toshihiro Horii
- Organizer
  The 12th Awaji International Forum on Infection and Immunity
- Place of Presentation
  淡路市
- Data Source
  KAKENHI-PROJECT-24249024
[Presentation] No allele specific immune response to Plasmodium falciparum SERA5 in participants that experienced malaria infection during the BK-SE36 malaria vaccine trial.2013
- Author(s)
  Nobuko Arisue, Nirianne M. Q. Palacpac, Masanori Yagi, Takahiro Tougan, Betty Balikagala Adoke Yeka, Edward Ntege, Bernard Kanoi, Katuro Osbert, Tom Egwang and Toshihiro Horii
- Organizer
  The 12th Awaji International Forum on Infection and Immunity
- Place of Presentation
  淡路市
- Data Source
  KAKENHI-PROJECT-24249024
[Presentation] ウガンダにおけるマラリアワクチンBK-SE36第Ib相臨床試験での抗体応答とマラリア感染後のブースト効果についての解析2013
- Author(s)
  八木正典、Nirianne M. Q. Palacpac、白井宏樹、有末伸子、板垣佐和子、東岸任弘、石井健、Thomas G. Egwang、堀井俊宏
- Organizer
  第82回日本寄生虫学会大会
- Place of Presentation
  東京都文京区／日本
- Data Source
  KAKENHI-PROJECT-24249024
[Presentation] 熱帯熱マラリア原虫SERA5のN末端反復配列は天然変性の特徴をもつ防御エピトープである2013
- Author(s)
  八木正典、Gilles Bang、有末伸子、東岸任弘、Nirianne M.Q. Palacpac、青枝大貴、石井健、Thomas G. Egwang、Pierre Druilhe、堀井俊宏
- Organizer
  第11回分子寄生虫マラリア研究フォーラム
- Place of Presentation
  長崎市
- Data Source
  KAKENHI-PROJECT-24249024
[Presentation] Immunogenicity of SE36 and boosting effect following infection in a clinical trial in Uganda2013
- Author(s)
  Masanori Yagi, Nirianne Marie Q. Palacpac, Hiroki Shirai, Nobuko Arisue, Sawako Itagaki, Takahiro Tougan, Ken J. Ishii, Thomas Egwang, Toshihiro Horii
- Organizer
  アジア・アフリカリサーチフォーラム
- Place of Presentation
  東京都文京区／日本
- Data Source
  KAKENHI-PROJECT-24249024
[Presentation] African HLA genes in a population that participated in the Phase 1b trial of BK-SE362013
- Author(s)
  Takahiro Tougan, Nirianne Q. Palacpac, Masanori Yagi, Thomas G Egwang and Toshihiro Horii
- Organizer
  Forum Cheju 16
- Place of Presentation
  ソウル
- Data Source
  KAKENHI-PROJECT-24249024
[Presentation] Identification and characterization of protective epitopes in malaria vaccine candidate SE362012
- Author(s)
  Masanori Yagi
- Organizer
  The 5th International CVRDC-RIMD Joint Symposium
- Place of Presentation
  韓国・済州島
- Data Source
  KAKENHI-PROJECT-22770151
[Presentation] Immunogenicity of SE36 and boosting effect following infection in a clinical trial in Uganda2012
- Author(s)
  M.Yagi, N.M.Q.Palacpac, E.Ntege, A.Yeka, B.Balikagala, N.Suzuki, H.Shirai, C.Nsereko, T.Okada, K.Tetsutani, N.Arisue, S.Itagaki, T.Tougan, K.J. .Ishii, S.Ueda, T.G. .Egwang, T.Horii
- Organizer
  第11回あわじしま感染症・免疫フォーラム
- Place of Presentation
  兵庫県淡路市／日本
- Data Source
  KAKENHI-PROJECT-24249024
[Presentation] ウガンダにおけるマラリアワクチンBK-SE36第Ib相臨床試験での抗体応答とマラリア感染後のブースト効果についての解析2012
- Author(s)
  八木正典、Nirianne Marie Q. Palacpac、白井宏樹、有末伸子、板垣佐和子、東岸任弘、石井健、Thomas Egwang、堀井俊宏
- Organizer
  第72回日本寄生虫学会東日本支部会・第10回分子寄生虫マラリアフォーラム合同大会
- Place of Presentation
  群馬県前橋市／日本
- Data Source
  KAKENHI-PROJECT-24249024
[Presentation] Identification and characterization of protective epitopes in malaria vaccine candidate SE362011
- Author(s)
  八木正典
- Organizer
  IUMS 2011 Sapporo
- Place of Presentation
  札幌市
- Year and Date
  2011-09-09
- Data Source
  KAKENHI-PROJECT-22770151
[Presentation] Identification and characterization of protective epitopes in malaria vaccine candidate SE362011
- Author(s)
  八木正典
- Organizer
  IUMS 2011 Sapporo
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2011-09-09
- Data Source
  KAKENHI-PROJECT-22770151
[Presentation] Immunogenicity of Whole-Parasite Vaccines against Plasmodium falciparum Involves Malarial Hemozoin and Host TLR92010
- Author(s)
  M.Yagi, T.Horii T., Tougan, T.Arisue, N.Palacpac M.Q, K.J.Ishii, C.Coban
- Organizer
  The 4th International RIMD-CVRDC Joint Symposium
- Place of Presentation
  岡山市、岡山/日本
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PLANNED-18073013

1. TANABE Kazuyuki (40047410)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
2. HORII Toshihiro (80142305)

# of Collaborated Projects: 4 results

# of Collaborated Products: 26 results
3. ARISUE Nobuko (00242339)

# of Collaborated Projects: 4 results

# of Collaborated Products: 17 results
4. TOUGAN Takahiro (20379093)

# of Collaborated Projects: 4 results

# of Collaborated Products: 21 results
5. TAI Kumiko (00187907)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
6. ISHII Ken (00448086)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. HAYAKAWA Toshiyuki (80418681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. AOSHI Taiki (10324344)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. PALACPAC Nirianne M. Q.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. COBAN Cevayir

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ZEYREK Fadile Yildiz

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. UDOMSANGPETCH Rachanee

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SATTABONGKOT Jetsumon

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. CULLETON Richard

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 松本芳嗣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 松本安喜

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YAGI Masanori 八木 正典

Research Projects

Research Products

Co-Researchers

Basic research of BK-SE36 malaria vaccine clinical study

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural analysis of Plasmodium falciparummalaria vaccine candidate antigen SERA5Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The diversity of Plasmodium SERA gene family : Adaptation of parasitism and host range

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

How P.vivax parasite maintains multiple infection in areas of low intensity malaria?

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Malaria genetic diversity as a basis for parasite growth and pathogenicity

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Protective epitopes of the Plasmodium falciparum SERA5 malaria vaccine reside in intrinsically unstructured N-terminal repetitive sequences.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Endemic Burkitt lymphoma is associated with strength and diversity of Plasmodium falciparummalaria stage-specific antigen antibody response2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phase 1b randomized trial and follow-up study in Uganda of the blood-stage malaria vaccine candidate BK-SE36.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lipocalin 2 bolsters innate and adaptive immune responses to blood-stage malaria infection by reinforcing host iron metabolism.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Geographic differentiation of polymorphismin the Plasmodium falciparum malariavaccine candidate gene SERA52012

Author(s)

Journal Title

Data Source

[Journal Article] Geographic differentiation of polymorphism in the Plasmodium falciparum malaria vaccine candidate gene SERA52012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serologic markers in relation to parasiteexposure history help to estimatetransmission dynamics of Plasmodium vivax2011

Author(s)

Journal Title

Data Source

[Journal Article] The Malarial Metabolite Hemozoin and Its Potential Use as a Vaccine Adjuvant2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Immunogenicity of Whole-Parasite Vaccines against Plasmodium falciparum Involves Malarial Hemozoin and Host TLR9.2010

Author(s)

Journal Title

Data Source

[Journal Article] The Malarial Metabolite Hemozoin and Its Potential Use as a Vaccine Adjuvant2010

Author(s)

Journal Title

NAID

YAGI Masanori 八木正典