Taira Ikuko 平郁子

… Alternative Names

平郁子タイライクコ

TAIRA Ikuko 平郁子

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Researcher Number	60453693
Other IDs
Affiliation (Current)	2025: 帝京平成大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2023: 帝京平成大学, 薬学部, 准教授 2015: 帝京平成大学, 薬学部, 講師 2008 – 2009: Teikyo University, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related / Biological pharmacy Except Principal Investigator Basic Section 47060:Clinical pharmacy-related / Natural medicines
Keywords	Principal Investigator TNF-alpha / 抗腫瘍薬 / DDS / ビフィズス菌 / 培地添加剤 / 遺伝子組換え微生物 / 薬物送達 / 抗腫瘍効果 / サイトカイン / 遺伝子組み換え微生物 … More / 嫌気性菌 / 遺伝子発現 / ニワトリ / in vivo遺伝子導入 / 大脳 / 神経軸索ガイダンス因子 / 刻印付け … More Except Principal Investigator 抗腫瘍薬 / 嫌気性菌 / DDS / ビフィズス菌 / ドラッグデリバリーシステム / 抗Ras抗体 / 組換えビフィズス菌 / 細菌 / 癌 / 抗腫瘍効果 Less

抗Ras抗体分泌ビフィズス菌を用いた新規癌治療法の開発
- Principal Investigator
  
  平裕一郎
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Teikyo Heisei University
The development of the drug delivery system via recombinant bifidobacteria aiming for an anti-cancer TNF-alpha preparation without adverse side effects.Principal Investigator
- Principal Investigator
  
  Taira Ikuko
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Teikyo Heisei University
The application of the drug delivery system by recombinant bifidobacteria to overcome the weak point of the low-molecule anticancer STAT3 inhibitors.
- Principal Investigator
  
  TAIRA Yuichiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Teikyo Heisei University
Development of the novel therapy against pancreatic cancer using highly absorbable curcumin preparation and recombinant bifidobacteria.
- Principal Investigator
  
  TAIRA Yuichiro
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Teikyo Heisei University
The analyses of the function of the axon guidance molecules in the filial imprinting of chickPrincipal Investigator
- Principal Investigator
  
  TAIRA Ikuko
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Biological pharmacy
- Research Institution
  Teikyo University

All 2023 2020 2019 2018 2016 2009 2008

All Journal Article Presentation Book

[Book] バイオ医薬品の開発と市場 20192018
- Author(s)
  平裕一郎　平郁子　石田功
- Total Pages
  266
- Publisher
  シーエムシー出版
- ISBN
  9784781313559
- Data Source
  KAKENHI-PROJECT-15K08000
[Journal Article] Anti-tumor effect of a recombinant Bifidobacterium strain secreting a claudin-targeting molecule in a mouse breast cancer model2020
- Author(s)
  Yoshimi Shimizu, Katsuhiro Isoda, Yuichiro Taira, Ikuko Taira, Masuo Kondoh, Isao Ishida
- Journal Title
  
  Eur J Pharmacol .
  
  Volume: 887 Pages: 173596-173596
- DOI
  10.1016/j.ejphar.2020.173596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07172, KAKENHI-PROJECT-19K16452
[Journal Article] Reviving Previous Therapeutics by Recombinant Anaerobic Bifidobacteria2019
- Author(s)
  Ikuko Taira, Yuichiro Taira, Masakazu Kato, Yoshimi Shimizu, Katuhiro Isoda, Hiromi Saitou and Isao Ishida
- Journal Title
  
  Biomed J Sci Tech Res.
  
  Volume: 12 Pages: 165-168
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08000
[Journal Article] Forefront of Cancer Targeting Therapy2018
- Author(s)
  Utoguchi N, Taira Y
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 138 Issue: 7 Pages: 901-902
- DOI
  10.1248/yakushi.17-00220-F
- NAID
  130007386669
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2018-07-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08000
[Journal Article] The hepatoprotective effect of lycopene on Con A-induced liver injury in mice2018
- Author(s)
  Shimizu Y, Mashima-Nemoto T, Hazawa M, Taira Y, Taira I, Ishida I, Isoda K
- Journal Title
  
  Die Pharmazie
  
  Volume: 73 Pages: 393-395
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08000
[Journal Article] Development of an Anticancer Therapy Using Recombinant <i>Bifidobacterium</i> as a New Drug Delivery System (DDS)2018
- Author(s)
  Taira Y, Taira I, Nisikawa T, Ishida I
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 138 Issue: 7 Pages: 923-930
- DOI
  10.1248/yakushi.17-00220-4
- NAID
  130007386667
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2018-07-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08000
[Journal Article] Suppression of the ecdysteroid-triggered growth arrest by a novel Drosophila membrane steroid binding protein2009
- Author(s)
  Fujii-Taira, I., Yamaguchi, S., Iijima, R., Natori, S., Homma, K.J.
- Journal Title
  
  FEBS Lett. 583
  
  Pages: 655-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890226
[Journal Article] Suppression of the ecdysteroid-triggered growth arrest by a novel Drosohila membrane steroid bindine urotein.2009
- Author(s)
  Fujii-Taira I, et al.
- Journal Title
  
  FEBS Lett. 583(4)
  
  Pages: 655-660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890226
[Journal Article] Gene expression profile in cerebrum in the filial imprinting of domestic chicks (Gallus gallus domesticus)2008
- Author(s)
  Yamaguchi S., Fujii-Taira I, Katagiri S., Izawa E., Fujimoto Y., Takeuchi H., Takano T., Matsushima T., Homma K.J.
- Journal Title
  
  Brain Res. Bull. 76
  
  Pages: 275-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890226
[Journal Article] The extracellular adenosine deaminase growth factor, ADGF/CECR1, plays a role in Xenopus embryogenesis via the adenosine/P1 receptor.2008
- Author(s)
  Iijima R., Kunieda T., Yamaguchi S., Kamigaki H., Fujii-Taira I, Sekimizu K., Kubo T., Nator, S., Homma K.J.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 2255-2264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890226
[Journal Article] Up-regulation of microtubule-associated protein 2 accompanying the filial imprinting of domestic chicks (Gallus gallus domesticus)2008
- Author(s)
  Yamaguchi S., Fujii-Taira I,, Murakami A., Hirose N., Aoki N., Izawa E., FujimotoY., Takano T., Matsushima T., Homma K.J.
- Journal Title
  
  Brain Res. Bull. 76
  
  Pages: 282-288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890226
[Presentation] 抗メソテリン-VHH抗体の性状解析とがん細胞株を用いた評価2023
- Author(s)
  清水芳実、常行航平、古川祥平、磯田勝広、平裕一郎、平郁子、石田功
- Organizer
  日本薬学会第１４３年会（札幌）　２０２３年３月２６日（日）
- Data Source
  KAKENHI-PROJECT-19K07172
[Presentation] 人体への安全性を考慮したビフィズス菌培養法2023
- Author(s)
  平郁子、平裕一郎、斎藤浩美、磯田勝広、清水芳実、石田功
- Organizer
  日本薬学会第１４３年会（札幌）　２０２３年３月２７日（月）
- Data Source
  KAKENHI-PROJECT-19K07172
[Presentation] 偏性嫌気性細菌を用いたトリプルネガティブ乳がん治療薬の開発2020
- Author(s)
  清水芳実、中山未希、篠原華穂、磯田勝広、平裕一郎、平郁子、斎藤浩美、石田功
- Organizer
  日本薬学会　第141年会（広島）
- Data Source
  KAKENHI-PROJECT-19K07172
[Presentation] EPR効果増強剤によるビフィズス菌腫瘍内集積数の増大2019
- Author(s)
  加藤雅和、平裕一郎、平郁子、川口愛夏、矢部貴美恵、大野華世、小倉祐太、後藤凪、清水芳実、磯田勝広、斎藤浩美、石田功
- Organizer
  日本薬学会第139年会（千葉）（2019年3月21日、幕張メッセ）
- Data Source
  KAKENHI-PROJECT-15K08000
[Presentation] 金ナノ粒子の薬物相互作用による傷害性の検討2019
- Author(s)
  越後谷美幸、磯田勝広、田中杏樹、藤盛千咲、木下結賀、佐藤梨花子、平裕一郎、平郁子、清水芳実、石田功
- Organizer
  日本薬学会第139年会（千葉）（2019年3月21日、幕張メッセ）
- Data Source
  KAKENHI-PROJECT-15K08000
[Presentation] 遺伝子組換えビフィズス菌をDDS に用いたがん治療薬の開発2018
- Author(s)
  平裕一郎
- Organizer
  第62回日本薬学会関東支部大会（2018.9.15、帝京平成大学薬学部）大会企画シンポジウム「DDS 研究からの創薬イノベーション」
- Invited
- Data Source
  KAKENHI-PROJECT-15K08000
[Presentation] CL4指向性抗腫瘍蛋白質を分泌する組換えビフィズス菌の作製2018
- Author(s)
  榎本健太、清水芳実、山内友梨奈、平裕一郎、平郁子、磯田勝広、斎藤浩美、石田功
- Organizer
  第62回日本薬学会関東支部大会（2018年9月15日、帝京平成大学薬学部）
- Data Source
  KAKENHI-PROJECT-15K08000
[Presentation] HepG2 細胞とマウスに対する金ナノ粒子の安全性の検討2018
- Author(s)
  藤盛千咲、磯田勝広、越後谷美幸、平裕一郎、平郁子、石田功
- Organizer
  第62回日本薬学会関東支部大会（2018年9月15日、帝京平成大学薬学部）
- Data Source
  KAKENHI-PROJECT-15K08000
[Presentation] がん細胞死誘導活性をもつTRAIL-R1 を標的とした新規3 価VHH 抗体分泌ビフィズス菌の安全性2018
- Author(s)
  西川毅、藤園友里、小出圭悟、平郁子、平裕一郎、石田功
- Organizer
  第62回日本薬学会関東支部大会（2018年9月15日、帝京平成大学薬学部）
- Data Source
  KAKENHI-PROJECT-15K08000
[Presentation] TRAIL-R1 を標的とした新規 3 価 VHH 抗体を分泌するビフィズス菌によるがん治療2016
- Author(s)
  西川毅, 平裕一郎, 平郁子, 斎藤浩美, 磯田勝広, 石田功
- Organizer
  第136年会　日本薬学会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-15K08000
[Presentation] 粒子径 10nm 銀ナノ粒子の安全性評価に関する検討2016
- Author(s)
  小林尚樹, 磯田勝広, 長谷川知也, 秋元義弘, 平裕一郎, 平郁子, 石田功
- Organizer
  第136年会　日本薬学会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-15K08000
[Presentation] ニワトリVSPはホスファターゼ活性の発現によって線維芽細胞の形態変化を引き起こす2009
- Author(s)
  平郁子
- Organizer
  日本生化学会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20890226
[Presentation] ニワトリVSPはホスファターゼ活性の発現によって線維芽細胞の形態変化を引き起こす2009
- Author(s)
  平郁子、山口真二、山田マミ、神垣ひろこ、黒川竜紀、岡村康司、本間光一
- Organizer
  第82回日本生化学会大会
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20890226
[Presentation] RNAiによるニワトリヒナ大脳での特異的遺伝子抑圧系の確立2008
- Author(s)
  片桐幸子、広瀬直樹、山口真二、平郁子、藤本康之、高野達哉、松島俊也、本間光一
- Organizer
  日本薬学会128回大会
- Data Source
  KAKENHI-PROJECT-20890226
[Presentation] 鳥類刻印付けの分子基盤の解明2008
- Author(s)
  片桐幸子、山口真二、平郁子、本間光一
- Organizer
  日本薬学会生物系薬学部会「ファーマ・バイオフォーラム2008」
- Place of Presentation
  日本薬学会長井記念ホール
- Year and Date
  2008-11-29
- Data Source
  KAKENHI-PROJECT-20890226

1. TAIRA Yuichiro (20581953)

# of Collaborated Projects: 4 results

# of Collaborated Products: 15 results
2. 石田功 (00415556)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results

Taira Ikuko 平 郁子

平 郁子 タイラ イクコ

TAIRA Ikuko 平 郁子

Research Projects

Research Products

Co-Researchers

抗Ras抗体分泌ビフィズス菌を用いた新規癌治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The development of the drug delivery system via recombinant bifidobacteria aiming for an anti-cancer TNF-alpha preparation without adverse side effects.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The application of the drug delivery system by recombinant bifidobacteria to overcome the weak point of the low-molecule anticancer STAT3 inhibitors.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of the novel therapy against pancreatic cancer using highly absorbable curcumin preparation and recombinant bifidobacteria.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The analyses of the function of the axon guidance molecules in the filial imprinting of chickPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] バイオ医薬品の開発と市場 20192018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Anti-tumor effect of a recombinant Bifidobacterium strain secreting a claudin-targeting molecule in a mouse breast cancer model2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reviving Previous Therapeutics by Recombinant Anaerobic Bifidobacteria2019

Author(s)

Journal Title

Data Source

[Journal Article] Forefront of Cancer Targeting Therapy2018

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] The hepatoprotective effect of lycopene on Con A-induced liver injury in mice2018

Author(s)

Journal Title

Data Source

[Journal Article] Development of an Anticancer Therapy Using Recombinant <i>Bifidobacterium</i> as a New Drug Delivery System (DDS)2018

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Suppression of the ecdysteroid-triggered growth arrest by a novel Drosophila membrane steroid binding protein2009

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of the ecdysteroid-triggered growth arrest by a novel Drosohila membrane steroid bindine urotein.2009

Author(s)

Journal Title

Taira Ikuko 平郁子

平郁子タイライクコ

TAIRA Ikuko 平郁子