Sasaki Yu 佐々木悠

Researcher Number	60466620
Other IDs	https://orcid.org/0000-0002-3939-9480
Affiliation (Current)	2024: 山形大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2021 – 2024: 山形大学, 医学部, 講師 2017 – 2020: 山形大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Basic Section 54040:Metabolism and endocrinology-related
Keywords	Principal Investigator 肥満 / 大腸癌 / RNA修飾 / GIP / インクレチン / 大腸がん / メタボリックシンドローム / インスリン抵抗性 / 大腸腺腫 / 大腸発がん … More / ABTB1 / RNAシークエンス / RNA転写後調節 / HuR / 代謝 / 腸内細菌 / トランスクリプトーム / 臨床 / GLP-1 / E. faecalis / LDL … More Except Principal Investigator 糖尿病 / 膵内分泌細胞 / 膵癌前癌病変 / 分化転換 / β細胞 Less

Elucidation of a novel mechanism of the regeneration of endocrine cells from unusual pancreatic ductal cells
- Principal Investigator
  
  岡野聡
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Yamagata University
Epitranscriptomics in Colorectal Cancer - A New Axis Linking Obesity, Metabolic Dysregulation and CarcinogenesisPrincipal Investigator
- Principal Investigator
  
  佐々木悠
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Yamagata University
Post-translational Modifications of RNA-binding Proteins in obesity-associated colorectal carcinogenesisPrincipal Investigator
- Principal Investigator
  
  Sasaki Yu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Yamagata University
Obesity and colorectal neoplasm: Interaction between the gut microbiota and obesity-associated somatic genomic signals from colorectal adenoma and carcinomaPrincipal Investigator
- Principal Investigator
  
  Sasaki Yu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamagata University

All 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Modulation of AMPK/ TET2/ 5-hmC axis in response to metabolic alterations as a novel pathway for obesity-related colorectal cancer development2023
- Author(s)
  Kon Takashi、Sasaki Yu、Abe Yasuhiko、Onozato Yusuke、Yagi Makoto、Mizumoto Naoko、Sakai Takayuki、Umehara Matsuki、Ito Minami、Nakamura Shuhei、Goto Hiroki、Ueno Yoshiyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 2858-2858
- DOI
  10.1038/s41598-023-29958-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08350
[Journal Article] Tu1543: CHARACTERISTICS OF THE GUT MICROBIOTA IN VISCERALLY OBESE PATIENTS WITH COLORECTAL ADENOMA2022
- Author(s)
  Sakai Takayuki、Sasaki Yu、Abe Yasuhiko、Nishise Shoichi、Sato Hidenori、Onozato Yusuke、Kon Takashi、Yagi Makoto、Mizumoto Naoko、Ito Minami、Umehara Matsuki、Nakamura Shuhei、Tsuchida Hidemoto、Goto Hiroki、Koseki Ayumi、Ueno Yoshiyuki
- Journal Title
  
  Gastroenterology
  
  Volume: 162 Issue: 7 Pages: S-1003-S-1004
- DOI
  10.1016/s0016-5085(22)62381-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08350
[Journal Article] Mo1108: A NOVEL HUR TARGET-THE ABTB1 GENE-IS INVOLVED IN A POTENTIAL MECHANISM OF OBESITY-RELATED COLORECTAL CARCINOGENESIS2022
- Author(s)
  Sasaki Yu、Abe Yasuhiko、Kon Takashi、Sato Hidenori、Onozato Yusuke、Yagi Makoto、Mizumoto Naoko、Sakai Takayuki、Ito Minami、Umehara Matsuki、Nakamura Shuhei、Tsuchida Hidemoto、Goto Hiroki、Koseki Ayumi、Ueno Yoshiyuki
- Journal Title
  
  Gastroenterology
  
  Volume: 162 Issue: 7 Pages: S-701
- DOI
  10.1016/s0016-5085(22)61641-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08350
[Journal Article] Reply: Serum pancreatic amylase and colorectal adenoma: From clinical research to practice2022
- Author(s)
  Sasaki Y、Abe Y、Nishise S、Ueno Y
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: 37 Issue: 11 Pages: 2189-2190
- DOI
  10.1111/jgh.15993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08350
[Journal Article] 大腸がんの発生・進展と腸内細菌の関わり2022
- Author(s)
  佐々木悠，阿部靖彦，東海林正邦，堺貴之，上野義之
- Journal Title
  
  Progress in Medicine
  
  Volume: 42 Pages: 47-52
- Data Source
  KAKENHI-PROJECT-20K08350
[Journal Article] Low serum pancreatic amylase levels as a novel latent risk factor for colorectal adenoma in non‐alcohol drinkers2022
- Author(s)
  Sasaki Yu、Abe Yasuhiko、Nishise Shoichi、Yagi Makoto、Mizumoto Naoko、Kon Takashi、Onozato Yusuke、Sakai Takayuki、Umehara Matsuki、Ito Minami、Ueno Yoshiyuki
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: 37 Issue: 4 Pages: 660-668
- DOI
  10.1111/jgh.15748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08350
[Journal Article] Insulin and glucose altered AMPK-TET2-5hmC axix toward on the obesity-related colorectal cancer development2021
- Author(s)
  Takashi Kon, Yu Sasaki, Yasuhiko Abe, Yusuke Onozato, Makoto Yagi, Naoko Mizumoto, Takayuki Sakai, Matsuki Umehara, Minami Ito, Ayumi Koseki, Yoshiyuki Ueno
- Journal Title
  
  Gastroenterology
  
  Volume: 160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08350
[Journal Article] Characteristics of the gut microbiome profile in obese patients with colorectal cancer2021
- Author(s)
  Shoji Masakuni、Sasaki Yu、Abe Yasuhiko、Nishise Shoichi、Yaoita Takao、Yagi Makoto、Mizumoto Naoko、Kon Takashi、Onozato Yusuke、Sakai Takayuki、Umehara Matsuki、Ito Minami、Koseki Ayumi、Murakami Ryoko、Miyano Yuki、Sato Hidenori、Ueno Yoshiyuki
- Journal Title
  
  JGH Open
  
  Volume: 5 Issue: 4 Pages: 498-507
- DOI
  10.1002/jgh3.12529
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08350
[Journal Article] 肥満、メタボリックシンドロームと消化管病態の関連性2020
- Author(s)
  佐々木悠，阿部靖彦，八木周，水本尚子，今孝志，小野里祐介，堺貴之，梅原松樹，伊藤南，上野義之
- Journal Title
  
  消化器・肝臓内科
  
  Volume: 8 Pages: 341-348
- Data Source
  KAKENHI-PROJECT-20K08350
[Journal Article] Association between High Levels of Circulating Chemerin and Colorectal Adenoma in Men2019
- Author(s)
  Yagi Makoto、Sasaki Yu、Abe Yasuhiko、Yaoita Takao、Sakuta Kazuhiro、Mizumoto Naoko、Shoji Masakuni、Onozato Yusuke、Kon Takashi、Nishise Shoichi、Ueno Yoshiyuki
- Journal Title
  
  Digestion
  
  Volume: - Issue: 5 Pages: 1-8
- DOI
  10.1159/000501477
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15920
[Journal Article] Impaired Secretion of Glucagon-Like Peptide 1 in Patients with Colorectal Adenoma after an Oral Glucose Load2018
- Author(s)
  Sasaki Yu、Abe Yasuhiko、Takeda Hiroaki、Nishise Shoichi、Yaoita Takao、Yagi Makoto、Sakuta Kazuhiro、Mizumoto Naoko、Shoji Masakuni、Onozato Yusuke、Kawata Sumio、Ueno Yoshiyuki
- Journal Title
  
  Digestion
  
  Volume: 97 Issue: 4 Pages: 324-332
- DOI
  10.1159/000486129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15920
[Presentation] 新たな大腸腺腫のリスク因子：血清膵アミラーゼ値の低下～大腸腺腫患者における非アルコール性脂肪肝・膵の解析～2022
- Author(s)
  佐々木悠、阿部靖彦、上野義之
- Organizer
  第108回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-20K08350
[Presentation] 肥満関連大腸癌における腸内細菌叢の解析2021
- Author(s)
  東海林正邦，佐々木悠，阿部靖彦，矢尾板孝夫，八木周，水本尚子，小野里祐介，今孝志，堺貴之，伊藤南，梅原松樹，佐藤秀則，西瀬祥一，上野義之
- Organizer
  第107回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-20K08350
[Presentation] 若年発症大腸癌（EOCRC）の臨床的特徴の検討2021
- Author(s)
  梅原松樹，佐々木悠，阿部靖彦, 八木周, 水本尚子, 小野里祐介, 今孝志, 堺貴之, 伊藤南, 上野義之
- Organizer
  第63回日本消化器病学会大会
- Data Source
  KAKENHI-PROJECT-20K08350
[Presentation] 肥満関連大腸がんにおけるTET2遺伝子発現の検討2021
- Author(s)
  今孝志，佐々木悠，阿部靖彦，小野里祐介，八木周，水本尚子，堺貴之，伊藤南，梅原松樹，小関歩，上野義之
- Organizer
  第107回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-20K08350
[Presentation] 大腸腺腫患者における腸内細菌叢の解析2021
- Author(s)
  堺貴之，佐々木悠，阿部靖彦, 西瀬祥一, 東海林正邦, 八木周, 水本尚子, 小野里祐介, 今孝志, 梅原松樹, 伊藤南, 上野義之
- Organizer
  第63回日本消化器病学会大会
- Data Source
  KAKENHI-PROJECT-20K08350
[Presentation] 大腸癌患者における腸内細菌叢と肥満・代謝異常との関連性2020
- Author(s)
  東海林正邦、佐々木悠、上野義之
- Organizer
  第106回日本消化器病学会総会、パネルディスカッション
- Data Source
  KAKENHI-PROJECT-17K15920
[Presentation] Ectopic fat accumulation in the liver and pancreas in patients with colorectal adenoma2020
- Author(s)
  Yu Sasaki, Yasuhiko Abe, Shoichi Nishise, Takao Yaoita, Makoto Yagi, Naoko Mizumoto, Masakuni Shoji, Yusuke Onozato, Takashi Kon, Takayuki Sakai, Yoshiyuki Ueno
- Organizer
  American Gastroenterological Association, DDW2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08350
[Presentation] 肥満関連大腸腫瘍における遺伝子変化の特徴についての検討2020
- Author(s)
  今孝志，佐々木悠，阿部靖彦，小野里祐介，佐藤秀則，矢尾板孝夫，八木周，水本尚子，東海林正邦，堺貴之，小関歩，上野義之
- Organizer
  第62回日本消化器病学会大会
- Data Source
  KAKENHI-PROJECT-20K08350
[Presentation] Obesity and colorectal neoplasm: identifying obesity-associated somatic genomic signals from colorectal adenoma and carcinoma2020
- Author(s)
  Takashi Kon, Yu Sasaki, Yasuhiko Abe, Takao Yaoita, Makoto Yagi, Naoko Mizumoto, Masakuni Shoji, Yusuke Onozato, Takayuki Sakai, Ayumi Koseki, Hidenori Sato, Yoshiyuki Ueno
- Organizer
  American Gastroenterological Association, DDW2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08350
[Presentation] Changes in the gut microbiota and their effect on pathogenesis in obese patients with colorectal cancer2020
- Author(s)
  Masakuni Shoji, Yu Sasaki, Yasuhiko Abe, Shoichi Nishise, Takao Yaoita, Makoto Yagi, Naoko Mizumoto, Yusuke Onozato, Takashi Kon, Takayuki Sakai, Ayumi Koseki, Hidenori Sato, Yoshiyuki Ueno
- Organizer
  American Gastroenterological Association, DDW2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08350
[Presentation] 大腸癌患者における腸内細菌叢と肥満・代謝異常との関連性2020
- Author(s)
  東海林正邦，佐々木悠，上野義之
- Organizer
  第106回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-20K08350
[Presentation] 早期胃癌の異時性再発を予測する分子マーカーの同定2020
- Author(s)
  佐々木悠，阿部靖彦，上野義之
- Organizer
  第106回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-20K08350
[Presentation] 肥満をリスク因子とする大腸腺腫とNAFLD合併例の検討2019
- Author(s)
  佐々木悠、阿部靖彦、矢尾板孝夫、八木周、水本尚子、東海林正邦、小野里祐介、今孝志、上野義之
- Organizer
  第9回肥満と消化器疾患研究会、一般演題
- Data Source
  KAKENHI-PROJECT-17K15920
[Presentation] 大腸癌患者における体重維持と腸内細菌叢の関連2019
- Author(s)
  東海林正邦、佐々木悠、阿部靖彦、矢尾板孝夫、八木周、水本尚子、小野里祐介、今孝志、上野義之
- Organizer
  第61回日本消化器病学会大会, JDDW2019 第26回日本消化器関連学会週間、一般演題
- Data Source
  KAKENHI-PROJECT-17K15920
[Presentation] 進行大腸がん患者における腸内細菌叢の解析2019
- Author(s)
  東海林正邦、佐々木悠、上野義之
- Organizer
  第105回日本消化器病学会総会、ワークショップ
- Data Source
  KAKENHI-PROJECT-17K15920
[Presentation] Cell-free DNAと大腸癌組織のgene variantsの比較2019
- Author(s)
  小野里祐介、佐々木悠、阿部靖彦、矢尾板孝夫、八木周、水本尚子、東海林正邦、今孝志、上野義之
- Organizer
  第105回日本消化器病学会総会、一般演題
- Data Source
  KAKENHI-PROJECT-17K15920
[Presentation] Association between colorectal adenoma and nonalcoholic fatty liver disease: sharing common risk factors with obesity and metabolic syndrome2019
- Author(s)
  Yu Sasaki, Yasuhiko Abe, Takao Yaoita, Makoto Yagi, Naoko Mizumoto, Masakuni Shoji, Yusuke Onozato, Takashi Kon, Shoichi Nishise, Yoshiyuki Ueno
- Organizer
  American Gastroenterological Association, DDW2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15920
[Presentation] Helicobacter pylori除菌後の体重変化～山形県コホートによる前向き検討～2019
- Author(s)
  佐々木悠、阿部靖彦、上野義之
- Organizer
  第105回日本消化器病学会総会、シンポジウム
- Data Source
  KAKENHI-PROJECT-17K15920
[Presentation] 大腸腺腫における肥満、メタボリックシンドローム～非アルコール性脂肪肝および脂肪膵の合併例の検討～2019
- Author(s)
  佐々木悠、阿部靖彦、上野義之
- Organizer
  第98回日本消化器内視鏡学会総会, JDDW2019 第26回日本消化器関連学会週間、ワークショップ
- Data Source
  KAKENHI-PROJECT-17K15920
[Presentation] 肥満、メタボリックシンドロームを共通の危険因子とする大腸腺腫とNAFLD併存例の解析2018
- Author(s)
  佐々木悠、阿部靖彦、上野義之
- Organizer
  第60回日本消化器病学会大会
- Data Source
  KAKENHI-PROJECT-17K15920
[Presentation] インクレチン分泌異常：肥満、メタボリックシンドロームからの大腸腫瘍に関連する新しい病態2018
- Author(s)
  佐々木悠、阿部靖彦、矢尾板孝夫、八木周、上野義之
- Organizer
  第204回日本消化器病学会東北支部例会
- Data Source
  KAKENHI-PROJECT-17K15920
[Presentation] インクレチンの分泌異常と大腸腺腫との関連性2018
- Author(s)
  佐々木悠、武田弘明、阿部靖彦、西瀬祥一、河田純男、上野義之
- Organizer
  第14回日本消化管学会総会
- Data Source
  KAKENHI-PROJECT-17K15920
[Presentation] 肥満、メタボリックシンドロームからの大腸腫瘍へのインクレチンの関与2017
- Author(s)
  佐々木悠、阿部靖彦、上野義之
- Organizer
  第103回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-17K15920

1. 岡野聡 (60300860)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 佐藤賢一 (10282055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Sasaki Yu 佐々木 悠

Research Projects

Research Products

Co-Researchers

Elucidation of a novel mechanism of the regeneration of endocrine cells from unusual pancreatic ductal cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Epitranscriptomics in Colorectal Cancer - A New Axis Linking Obesity, Metabolic Dysregulation and CarcinogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Post-translational Modifications of RNA-binding Proteins in obesity-associated colorectal carcinogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Obesity and colorectal neoplasm: Interaction between the gut microbiota and obesity-associated somatic genomic signals from colorectal adenoma and carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Modulation of AMPK/ TET2/ 5-hmC axis in response to metabolic alterations as a novel pathway for obesity-related colorectal cancer development2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tu1543: CHARACTERISTICS OF THE GUT MICROBIOTA IN VISCERALLY OBESE PATIENTS WITH COLORECTAL ADENOMA2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mo1108: A NOVEL HUR TARGET-THE ABTB1 GENE-IS INVOLVED IN A POTENTIAL MECHANISM OF OBESITY-RELATED COLORECTAL CARCINOGENESIS2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reply: Serum pancreatic amylase and colorectal adenoma: From clinical research to practice2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 大腸がんの発生・進展と腸内細菌の関わり2022

Author(s)

Journal Title

Data Source

[Journal Article] Low serum pancreatic amylase levels as a novel latent risk factor for colorectal adenoma in non‐alcohol drinkers2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Insulin and glucose altered AMPK-TET2-5hmC axix toward on the obesity-related colorectal cancer development2021

Author(s)

Journal Title

Data Source

[Journal Article] Characteristics of the gut microbiome profile in obese patients with colorectal cancer2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 肥満、メタボリックシンドロームと消化管病態の関連性2020

Author(s)

Journal Title

Data Source

[Journal Article] Association between High Levels of Circulating Chemerin and Colorectal Adenoma in Men2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impaired Secretion of Glucagon-Like Peptide 1 in Patients with Colorectal Adenoma after an Oral Glucose Load2018

Author(s)

Journal Title

DOI

Data Source

Sasaki Yu 佐々木悠