YOSHIDA NAOYA 吉田直矢

… Alternative Names

Researcher Number	60467983
Other IDs
Affiliation (Current)	2021: 熊本大学, 病院, 特任教授
Affiliation (based on the past Project Information) *help	2019 – 2020: 熊本大学, 病院, 特任准教授 2018: 熊本大学, 医学部附属病院, 特任准教授 2017: 熊本大学, 医学薬学研究部, その他 2015 – 2016: 熊本大学, 大学院生命科学研究部(医), 講師 2013 – 2014: 熊本大学, 大学院生命科学研究部, 講師 2008 – 2010: 熊本大学, 医学部附属病院, 非常勤診療医師
Review Section/Research Field	Principal Investigator Digestive surgery / Basic Section 55010:General surgery and pediatric surgery-related Except Principal Investigator Digestive surgery / General surgery / Basic Section 50010:Tumor biology-related
Keywords	Principal Investigator 食道扁平上皮癌 / 予後因子 / PPARγ / 新規PPARγ agonist / cetuximab / p21 / Akt / EGFR / agonist / 低分子化合物 … More Except Principal Investigator 食道癌 / 消化器癌 / 腫瘍免疫 / microbiome / 食道外科学 / mTOR / RAD001 / ラミミン-332 / GIST / リスク分類 / FBXW7 / 術後補助療法 / イマチニブ耐性 / 再発予測因子 / 分子標的薬耐性 / CCN family / バイオマーカー / エピジェネティクス / がん代謝 / genetic change / epigenetic change / cancer metabolism / immunity / predictive marker / 腸内細菌叢 / LINE-1 / Fusobacterium / 16S rRNA シークエンス / LNE-1 / Fusobacterium nucleatum / epigenetics / esophageal cancer / 胃癌 / 腹膜播種 / 腫瘍微小環境 / liquid biopsy Less

胃癌腹膜播種における腫瘍不均一性および腫瘍微小環境を標的とした革新的治療法の開発Ongoing
- Principal Investigator
  
  岩槻政晃
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kumamoto University
飲酒喫煙が食道癌診療に及ぼすリスクの包括的評価における平均赤血球容積の意義Principal InvestigatorOngoing
- Principal Investigator
  
  吉田直矢
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kumamoto University
Investigation of CCN family for development and drug resistance of gastrointestinal cancers
- Principal Investigator
  
  Nagai Youhei
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Comprehensive analysis of gut microbiome and epigenetic changes in esophageal cancer.
- Principal Investigator
  
  Baba Yoshifumi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kumamoto University
The identification of molecular markers associated with resistance for molecular targeted agents in GIST
- Principal Investigator
  
  IWATSUKI Masaaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kumamoto University
Comprehensive analysis for the association between microbiome in the gastric mucosa and malignant potential of gastric cancerPrincipal Investigator
- Principal Investigator
  
  YOSHIDA Naoya
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Tumor-suppressive effects and mechanism of a novel PPAR gamma agonist in esophageal canerPrincipal Investigator
- Principal Investigator
  
  YOSHIDA Naoya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Clinical significance of Laminin-332 and its potential as a therapeutic target
- Principal Investigator
  
  MIYANARI Nobutomo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University

All 2020 2019 2018 2017 2016 2015 2014 2009

All Journal Article Presentation

[Journal Article] Mucosal cancer-associated microbes and anastomotic leakage after resection of colorectal carcinoma2020
- Author(s)
  Mima Kosuke、Sakamoto Yuki、Kosumi Keisuke、Ogata Yoko、Miyake Keisuke、Hiyoshi Yukiharu、Ishimoto Takatsugu、Iwatsuki Masaaki、Baba Yoshifumi、Iwagami Shiro、Miyamoto Yuji、Yoshida Naoya、Ogino Shuji、Baba Hideo
- Journal Title
  
  Surgical Oncology
  
  Volume: 32 Pages: 63-68
- DOI
  10.1016/j.suronc.2019.11.005
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04273, KAKENHI-PROJECT-18H02694, KAKENHI-PROJECT-17H05094, KAKENHI-PROJECT-18K19586
[Journal Article] Prognostic and clinical impact of PD-L2 and PD-L1 expression in a cohort of 437 oesophageal cancers2020
- Author(s)
  Okadome Kazuo、Baba Yoshifumi、Nomoto Daichi、Yagi Taisuke、Kalikawe Rebecca、Harada Kazuto、Hiyoshi Yukiharu、Nagai Yohei、Ishimoto Takatsugu、Iwatsuki Masaaki、Iwagami Shiro、Miyamoto Yuji、Yoshida Naoya、Watanabe Masayuki、Komohara Yoshihiro、Shono Takashi、Sasaki Yutaka、Baba Hideo
- Journal Title
  
  British Journal of Cancer
  
  Volume: 122 Pages: 1535-1543
- DOI
  10.1038/s41416-020-0811-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17437, KAKENHI-PROJECT-19K18094, KAKENHI-PROJECT-17H04273, KAKENHI-PROJECT-17K10596
[Journal Article] Prognostic Nutritional Index, Tumor-infiltrating Lymphocytes, and Prognosis in Patients with Esophageal Cancer2020
- Author(s)
  Okadome Kazuo、Baba Yoshifumi、Yagi Taisuke、Kiyozumi Yuki、Ishimoto Takatsugu、Iwatsuki Masaaki、Miyamoto Yuji、Yoshida Naoya、Watanabe Masayuki、Baba Hideo
- Journal Title
  
  Annals of Surgery
  
  Volume: 271 Pages: 1-1
- DOI
  10.1097/sla.0000000000002985
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17KK0195, KAKENHI-PROJECT-17H04273, KAKENHI-PROJECT-17K19702, KAKENHI-PROJECT-18K19586
[Journal Article] Lysyl oxidase impacts disease outcomes and correlates with global DNA hypomethylation in esophageal cancer2019
- Author(s)
  Kalikawe Rebecca、Baba Yoshifumi、Nomoto Daichi、Okadome Kazuo、Miyake Keisuke、Eto Kojiro、Hiyoshi Yukiharu、Nagai Youhei、Iwatsuki Masaaki、Ishimoto Takatsugu、Iwagami Shiro、Miyamoto Yuji、Yoshida Naoya、Watanabe Masayuki、Baba Hideo
- Journal Title
  
  Cancer Science
  
  Volume: 110 Pages: 3727-3737
- DOI
  10.1111/cas.14214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09076, KAKENHI-PROJECT-17H04273
[Journal Article] PD-L1 Expression, Tumor-infiltrating Lymphocytes, and Clinical Outcome in Patients With Surgically Resected Esophageal Cancer2019
- Author(s)
  Yagi T, Baba Y, Ishimoto T, Iwatsuki M, Miyamoto Y, Yoshida N, Watanabe M, Baba H.
- Journal Title
  
  Annals of Surgery
  
  Volume: Dec 4 Pages: 471-478
- DOI
  10.1097/sla.0000000000002616
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10596, KAKENHI-PROJECT-17H04273, KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-16K15595, KAKENHI-PROJECT-19K18094
[Journal Article] Morphological lymphocytic reaction, patient prognosis and?PD‐1 expression after surgical resection for oesophageal cancer2019
- Author(s)
  Baba Y.、Yagi T.、Kosumi K.、Okadome K.、Nomoto D.、Eto K.、Hiyoshi Y.、Nagai Y.、Ishimoto T.、Iwatsuki M.、Iwagami S.、Miyamoto Y.、Yoshida N.、Komohara Y.、Watanabe M.、Baba H.
- Journal Title
  
  BJS
  
  Volume: 106 Pages: 1352-1361
- DOI
  10.1002/bjs.11301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16750, KAKENHI-PROJECT-17H04273, KAKENHI-PROJECT-17K10596
[Journal Article] Tumour-associated macrophages are associated with poor prognosis and programmed death ligand 1 expression in oesophageal cancer2019
- Author(s)
  Yagi Taisuke、Baba Yoshifumi、Okadome Kazuo、Kiyozumi Yuki、Hiyoshi Yukiharu、Ishimoto Takatsugu、Iwatsuki Masaaki、Miyamoto Yuji、Yoshida Naoya、Watanabe Masayuki、Komohara Yoshihiro、Baba Hideo
- Journal Title
  
  European Journal of Cancer
  
  Volume: 111 Pages: 38-49
- DOI
  10.1016/j.ejca.2019.01.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18094, KAKENHI-PROJECT-17H04273
[Journal Article] Indoleamine 2, 3‐dioxygenase 1 promoter hypomethylation is associated with poor prognosis in patients with esophageal cancer2019
- Author(s)
  Kiyozumi Yuki、Baba Yoshifumi、Okadome Kazuo、Yagi Taisuke、Ogata Yoko、Eto Kojiro、Hiyoshi Yukiharu、Ishimoto Takatsugu、Iwatsuki Masaaki、Iwagami Shiro、Miyamoto Yuji、Yoshida Naoya、Watanabe Masayuki、Baba Hideo
- Journal Title
  
  Cancer Science
  
  Volume: 110(6) Pages: 1863-1871
- DOI
  10.1111/cas.14028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09076, KAKENHI-PROJECT-19K18095
[Journal Article] Tumor Long-interspersed Nucleotide Element-1 Methylation Level and Immune Response to Esophageal Cancer2019
- Author(s)
  Kosumi Keisuke、Baba Yoshifumi、Okadome Kazuo、Yagi Taisuke、Kiyozumi Yuki、Yoshida Naoya、Watanabe Masayuki、Baba Hideo
- Journal Title
  
  Annals of Surgery
  
  Volume: - Pages: 1-1
- DOI
  10.1097/sla.0000000000003264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09076, KAKENHI-PROJECT-17H04273
[Journal Article] The role of FBXW7, a cell-cycle regulator, as a predictive marker of recurrence of gastrointestinal stromal tumors.2019
- Author(s)
  Koga Yuki、Iwatsuki Masaaki、Yamashita Kohei、Kiyozumi Yuki、Kurashige Junji、Masuda Toshiro、Eto Kojiro、Iwagami Shiro、Harada Kazuto、Ishimoto Takatsugu、Baba Yoshifumi、Yoshida Naoya、Miyanari Nobutomo、Takamori Hiroshi、Ajani Jaffer A.、Baba Hideo
- Journal Title
  
  Gastric Cancer.
  
  Volume: 22(6) Pages: 1100-1108
- DOI
  10.1007/s10120-019-00950-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10463, KAKENHI-PROJECT-18K08623, KAKENHI-PROJECT-19K18154, KAKENHI-PROJECT-16KK0184
[Journal Article] Intratumoral Fusobacterium Nucleatum Levels Predict Therapeutic Response to Neoadjuvant Chemotherapy in Esophageal Squamous Cell Carcinoma2019
- Author(s)
  Yamamura Kensuke、Izumi Daisuke、Kandimalla Raju、Sonohara Fuminori、Baba Yoshifumi、Yoshida Naoya、Kodera Yasuhiro、Baba Hideo、Goel Ajay
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 25 Pages: 6170-6179
- DOI
  10.1158/1078-0432.ccr-19-0318
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04273, KAKENHI-PROJECT-18H02694, KAKENHI-PROJECT-18K16261
[Journal Article] Effect of Resection of the Thoracic Duct and Surrounding Lymph Nodes on Short- and Long-Term and Nutritional Outcomes After Esophagectomy for Esophageal Cancer2019
- Author(s)
  Yoshida Naoya、Nagai Yohei、Baba Yoshifumi、Miyamoto Yuji、Iwagami Shiro、Iwatsuki Masaaki、Hiyoshi Yukiharu、Eto Kojiro、Ishimoto Takatsugu、Kiyozumi Yuki、Nomoto Daichi、Akiyama Takahiko、Imamura Yu、Watanabe Masayuki、Baba Hideo
- Journal Title
  
  Annals of Surgical Oncology
- DOI
  10.1245/s10434-019-07304-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10596
[Journal Article] Progress in characterizing the linkage between Fusobacterium nucleatum and gastrointestinal cancer.2019
- Author(s)
  Liu Yang、Baba Yoshifumi、Ishimoto Takatsugu、Iwatsuki Masaaki、Hiyoshi Yukiharu、Miyamoto Yuji、Yoshida Naoya、Wu Rong、Baba Hideo
- Journal Title
  
  J Gastroenterol
  
  Volume: 54 Pages: 33-41
- DOI
  10.1007/s00535-018-1512-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19586, KAKENHI-PROJECT-17H04273, KAKENHI-PROJECT-16K10504, KAKENHI-PROJECT-17K19702, KAKENHI-PROJECT-19K18094, KAKENHI-PROJECT-18H02694
[Journal Article] Recent Incidence Trend of Surgically Resected Esophagogastric Junction Adenocarcinoma and Microsatellite Instability Status in Japanese Patients2018
- Author(s)
  Imamura Y, Watanabe M, Toihata T, Takamatsu M,　Kawachi H, Haraguchi I, Ogata Y, Yoshida N, Saeki H, Oki E, Taguchi K, Yamamoto M, Morita M, Mine S, Hiki N, Baba H, Sano T.
- Journal Title
  
  Digestion
  
  Volume: 99 Pages: 6-13
- DOI
  10.1159/000494406
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08638, KAKENHI-PROJECT-16H06259, KAKENHI-PROJECT-16K10504, KAKENHI-PROJECT-17K19619
[Journal Article] Long Interspersed Element-1 Methylation Level as a Prognostic Biomarker in Gastrointestinal Cancers.2018
- Author(s)
  Baba Y, Yagi T, Sawayama H, Hiyoshi Y, Ishimoto T, Iwatsuki M, Miyamoto Y, Yoshida N, Baba H.
- Journal Title
  
  Digestion.
  
  Volume: 97(1) Pages: 26-30
- DOI
  10.1159/000484104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10596, KAKENHI-PROJECT-16K19942
[Journal Article] Clinical Importance of Mean Corpuscular Volume as a Prognostic Marker After Esophagectomy for Esophageal Cancer2018
- Author(s)
  Yoshida Naoya、Kosumi Keisuke、Tokunaga Ryuma、Baba Yoshifumi、Nagai Yohei、Miyamoto Yuji、Iwagami Shiro、Iwatsuki Masaaki、Hiyoshi Yukiharu、Ishimoto Takatsugu、Eto Kojiro、Imamura Yu、Watanabe Masayuki、Baba Hideo
- Journal Title
  
  Annals of Surgery
  
  Pages: 1-1
- DOI
  10.1097/sla.0000000000002971
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10596
[Journal Article] IDO1 Expression Is Associated With Immune Tolerance and Poor Prognosis in Patients With Surgically Resected Esophageal Cancer2018
- Author(s)
  Kiyozumi Y, Baba Y, Okadome K, Yagi T, Ishimoto T, Iwatsuki M, Miyamoto Y, Yoshida N, Watanabe M, Komohara Y, Baba H.
- Journal Title
  
  Annals of Surgery
  
  Volume: Mar 27 Pages: 1-1
- DOI
  10.1097/sla.0000000000002754
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19702, KAKENHI-PROJECT-18K19586, KAKENHI-PROJECT-17KK0195, KAKENHI-PROJECT-17H04273
[Journal Article] Influence of Neoadjuvant Chemotherapy on Short-term Outcomes After Minimally Invasive Esophagectomy for Esophageal Cancer2018
- Author(s)
  NOMOTO DAICHI、YOSHIDA NAOYA、AKIYAMA TAKAHIKO、KIYOZUMI YUKI、ETO KOJIRO、HIYOSHI YUKIHARU、NAGAI YOHEI、IWATSUKI MASAAKI、IWAGAMI SHIRO、BABA YOSHIFUMI、MIYAMOTO YUJI、BABA HIDEO
- Journal Title
  
  Anticancer Research
  
  Volume: 39 Pages: 471-475
- DOI
  10.21873/anticanres.13136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10596
[Journal Article] PLOD2 as a potential regulator of peritoneal dissemination in gastric cancer.2018
- Author(s)
  Kiyozumi Y, Iwatsuki M, Kurashige J, Ogata Y, Yamashita K, Koga Y, Toihata T, Hiyoshi Y, Ishimoto T, Baba Y, Miyamoto Y, Yoshida N, Yanagihara K, Mimori K, Baba H.
- Journal Title
  
  Int J Cancer.
  
  Volume: Mar 30 Pages: 1202-1211
- DOI
  10.1002/ijc.31410
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10463, KAKENHI-PROJECT-17K19608
[Journal Article] Nrf2 promotes esophageal cancer cell proliferation via metabolic reprogramming and ROS detoxification2018
- Author(s)
  Kitano Y, Baba Y, Nakagawa S, Miyake K, Iwatsuki M, Ishimoto T, Yamashita YI, Yoshida N, Watanabe M, Nakao M, Baba H.
- Journal Title
  
  J Pathol
  
  Volume: 244(3) Pages: 346-357
- DOI
  10.1002/path.5021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10596, KAKENHI-PROJECT-15H04707, KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-18K16370
[Journal Article] Neoadjuvant and adjuvant therapy for gastrointestinal stromal tumors2018
- Author(s)
  Iwatsuki Masaaki、Harada Kazuto、Iwagami Shiro、Eto Kojiro、Ishimoto Takatsugu、Baba Yoshifumi、Yoshida Naoya、Ajani Jaffer A.、Baba Hideo
- Journal Title
  
  Annals of Gastroenterological Surgery
  
  Volume: 3 Pages: 43-49
- DOI
  10.1002/ags3.12211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10463
[Journal Article] Prognostic Factors of Salvage Esophagectomy for Residual or Recurrent Esophageal Squamous Cell Carcinoma After Definitive Chemoradiotherapy.2018
- Author(s)
  Kiyozumi Y, Yoshida N, Ishimoto T, Yagi T, Koga Y, Uchihara T, Sawayama H, Hiyoshi Y, Iwatsuki M, Baba Y, Miyamoto Y, Watanabe M, Matsuyama T, Oya N, Baba H.
- Journal Title
  
  World J Surg.
  
  Volume: Feb 8.
- DOI
  10.1007/s00268-018-4536-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10596, KAKENHI-PROJECT-16K19942
[Journal Article] The microbiome and hepatobiliary-pancreatic cancers.2017
- Author(s)
  Mima K, Nakagawa S, Sawayama H, Ishimoto T, Imai K, Iwatsuki M, Hashimoto D, Baba Y, Yamashita YI, Yoshida N, Chikamoto A, Baba H
- Journal Title
  
  Cancer Lett.
  
  Volume: 402 Pages: 9-15
- DOI
  10.1016/j.canlet.2017.05.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10504, KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-16K19942
[Journal Article] The role of intestinal bacteria in the development and progression of gastrointestinal tract neoplasms.2017
- Author(s)
  Mima K, Ogino S, Nakagawa S, Sawayama H, Kinoshita K, Krashima R, Ishimoto T, Imai K, Iwatsuki M, Hashimoto D, Baba Y, Sakamoto Y, Yamashita YI, Yoshida N, Chikamoto A, Ishiko T, Baba H
- Journal Title
  
  Surg Oncol.
  
  Volume: 26(4) Pages: 368-376
- DOI
  10.1016/j.suronc.2017.07.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10504, KAKENHI-PROJECT-17H05094, KAKENHI-PROJECT-16K19942
[Journal Article] Colorectal cancer stem cells acquire chemoresistance through the upregulation of F-Box/WD repeat-containing protein 7 and the consequent degradation of c-myc.2017
- Author(s)
  Izumi D, Ishimoto T, Miyake K, Eto T, Arima K, Kiyozumi Y, Uchihara T, Kurashige J, Iwatsuki M, Baba Y, Sakamoto Y, Miyamoto Y, Yoshida N, Watanabe M, Goel A, Tan P, Baba H.
- Journal Title
  
  Stem Cells
  
  Volume: 35(9) Pages: 2027-2036
- DOI
  10.1002/stem.2668
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10596, KAKENHI-PROJECT-17K16570, KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-15K10122, KAKENHI-PROJECT-16K15595
[Journal Article] Review of the gut microbiome and esophageal cancer: Pathogenesis and potential clinical implications.2017
- Author(s)
  Baba Y, Iwatsuki M, Yoshida N, Watanabe M, Baba H
- Journal Title
  
  Ann Gastroenterol Surg
  
  Volume: 1 Pages: 99-104
- DOI
  10.1002/ags3.12014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10504
[Journal Article] Fusobacterium nucleatum in gastroenterological cancer: Evaluation of measurement methods using quantitative polymerase chain reaction and a literature review.2017
- Author(s)
  Yamamura K, Baba Y, Miyake K, Nakamura K, Shigaki H, Mima K, Kurashige J, Ishimoto T, Iwatsuki M, Sakamoto Y, Yamashita Y, Yoshida N, Watanabe M, Baba H
- Journal Title
  
  Oncol Lett.
  
  Volume: 14(6) Pages: 6373-6378
- DOI
  10.3892/ol.2017.7001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10504, KAKENHI-PROJECT-17K10596
[Journal Article] Duration of Smoking Cessation and Postoperative Morbidity After Esophagectomy for Esophageal Cancer: How Long Should Patients Stop Smoking Before Surgery?2016
- Author(s)
  Yoshida N, Baba Y, Hiyoshi Y, Shigaki H, Kurashige J, Sakamoto Y, Miyamoto Y, Iwatsuki M, Ishimoto T, Kosumi K, Sugihara H, Harada K, Tokunaga R, Izumi D, Watanabe M, Baba H.
- Journal Title
  
  World J Surg
  
  Volume: 40(1) Pages: 142-7
- DOI
  10.1007/s00268-015-3236-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462028, KAKENHI-PROJECT-16K19943
[Journal Article] Co-occurrence of liver metastasis of gastrointestinal stromal tumor and hepatocellular carcinoma: a case report.2016
- Author(s)
  Yamashita K, Baba Y, Kurashige J, Iwatsuki M, Imai K, Hashimoto D, Sakamoto Y, Chikamoto A, Yoshida N, Beppu T, Baba H.
- Journal Title
  
  Surg Case Rep
  
  Volume: 2（1） Pages: 86-86
- DOI
  10.1186/s40792-016-0212-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10463
[Journal Article] Human microbiome Fusobacterium nucleatum in esophageal cancer tissue is associated with prognosis.2016
- Author(s)
  Yamamura K, Baba Y, Nakagawa S, Mima K, Miyake K, Nakamura K, Sawayama H, Kinoshita K, Ishimoto T, Iwatsuki M, Sakamoto Y, Yamashita Y, Yoshida N, Watanabe M, Baba H.
- Journal Title
  
  Clin Cancer Res
  
  Volume: 22(22) Pages: 5574-5581
- DOI
  10.1158/1078-0432.ccr-16-1786
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10504, KAKENHI-PROJECT-16K15595, KAKENHI-PROJECT-16K19942
[Journal Article] Triangulating Stapling Technique Covered with the Pedicled Omental Flap for Esophagogastric Anastomosis: A Safe Anastomosis with Fewer Complications2015
- Author(s)
  Yoshida N, Baba Y, Watanabe M, Hiyoshi Y, Ishimoto T, Iwagami S, Kurashige J, Sakamoto Y, Miyamoto Y, Baba H
- Journal Title
  
  J Am Coll Surg
  
  Volume: 220(2)
- DOI
  10.1016/j.jamcollsurg.2014.10.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462028, KAKENHI-PROJECT-25861200
[Journal Article] Reconstruction Using a Pedunculated Gastric Tube with Duodenal Transection After Esophagectomy and Pharyngolaryngectomy.2015
- Author(s)
  Yoshida N, Baba Y, Oda E, Kosumi K, Ishimoto T, Watanabe M, Hiyoshi Y, Iwagami S, Kurashige J, Sakamoto Y, Miyamoto Y, Sugihara H, Eto K, Harada K, Baba H.
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 22(13) Pages: 4352-4352
- DOI
  10.1245/s10434-015-4427-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462028
[Journal Article] An original scoring system for predicting postoperative morbidity after esophagectomy for esophageal cancer2015
- Author(s)
  Yoshida N, Baba Y, Watanabe M, Ida S, Ishimoto T, Karashima R, Iwagami S, Imamura Y, Sakamoto Y, Miyamoto Y, Baba H
- Journal Title
  
  Surg Today
  
  Volume: 45(3) Pages: 346-54
- DOI
  10.1007/s00595-014-0958-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462028
[Journal Article] Influence of preoperative docetaxel, cisplatin, and 5-fluorouracil on the incidence of complications after esophagectomy for resectable advanced esophageal cancer2014
- Author(s)
  108 Yoshida N., Watanabe M., Baba Y., Ishimoto T., Iwagami S., Sakamoto Y., Miyamoto Y., Karashima R., Baba H
- Journal Title
  
  Dis Esophagus
  
  Volume: 27 Pages: 374-379
- DOI
  10.1111/dote.12117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591950, KAKENHI-PROJECT-25462028
[Journal Article] High expression of glucose transporter 1 on primary lesions of esophageal squamous cell carcinoma is associated with hematogenous recurrence2014
- Author(s)
  Sawayama H, Ishimoto T, Watanabe M, Yoshida N, Baba Y, Sugihara H, Izumi D, Kurashige J, Baba H
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 21(5) Pages: 1756-62
- DOI
  10.1245/s10434-013-3371-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462028, KAKENHI-PROJECT-25861200, KAKENHI-PROJECT-26713042, KAKENHI-PROJECT-26893203
[Journal Article] Small molecule agonists of PPAR-γ exert therapeutic effects in esophageal cancer2014
- Author(s)
  Sawayama H, Ishimoto T, Watanabe M, Yoshida N, Sugihara H, Kurashige J, Hirashima K, Iwatsuki M, Baba Y, Oki E, Morita M, Shiose Y, Baba H
- Journal Title
  
  Cancer Research
  
  Volume: 74 Pages: 575-585
- DOI
  10.1158/0008-5472.can-13-1836
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591966, KAKENHI-PROJECT-25462027, KAKENHI-PROJECT-25462028
[Journal Article] p12CDK2-AP1 is associated with tumor progression and a poor prognosis in esophageal squamous cell carcinoma.2009
- Author(s)
  Hiyoshi Y, Watanabe M, Hirashima K, Karashima R, Sato N, Imamura Y, Nagai Y, Yoshida N, Toyama E, Hayashi N, Baba H.
- Journal Title
  
  Oncol Rep. 22(1)
  
  Pages: 35-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591572
[Journal Article] Transcervical superior mediastinal lymph node dissection combined with transhiatal lower esophageal dissection before transthoracic esophagectomy : a safe approach for salvage esophagectomy.2009
- Author(s)
  Watanabe M, Yoshida N, Karashima R, Sato N, Hirashima K, Imamura Y, Hiyoshi Y, Nagai Y, Iwagami S, Toyama E, Hayashi N, Baba H.
- Journal Title
  
  J Am Coll Surg. 208(4)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591572
[Journal Article] MicroRNA-21 regulates the proliferation and invasion in esophageal squamous cell carcinoma.2009
- Author(s)
  Hiyoshi Y, Kamohara H, Karashima R, Sato N, Imamura Y, Nagai Y, Yoshida N, Toyama E, Hayashi N, Watanabe M, Baba H.
- Journal Title
  
  Clin Cancer Res. 15(6)
  
  Pages: 1915-1922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591572
[Journal Article] The relationship between the glucose transporter type 1 expression and F-fluorodeoxyglucose uptake in esophageal squamous cell carcinoma.2009
- Author(s)
  Hiyoshi Y, Watanabe M, Imamura Y, Nagai Y, Baba Y, Yoshida N, Toyama E, Hayashi N, Baba H.
- Journal Title
  
  Oncology. 76(4)
  
  Pages: 286-292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591572
[Presentation] Microbiome Furobacterium nucleatum has an effect on chemotherapeutic response in esophageal squamous cell carcinoma.2019
- Author(s)
  Baba Y, Li Y, Eto K, Hiyoshi Y, Ishimoto T, Iwatsuki M, Iwagami S, Miyamoto Y, Yoshida N, Baba H
- Organizer
  11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10504
[Presentation] Glucose Transporter 1 regulates cell glycolysis and proliferation in Gastrointestinal stromal tumor and its clinicopathological significance2019
- Author(s)
  Masaaki Iwatsuki, Hiroshi Sawayama, Daisuke Kuroda, Yuki Koga, Kazuto Harada, Kohei Yamashita, Shiro Iwagami, Kojiro Eto, Takatsugu Ishimoto, Yoshifumi Baba, Naoya Yoshida, Jaffer A. Ajani and Hideo Baba
- Organizer
  2019 AACR Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10463
[Presentation] 食道癌コホートを用いたFusobacterium nucleatumと腫瘍免疫の統合解析2019
- Author(s)
  小澄敬祐、馬場祥史、山村謙介、岡留一雄、八木泰佑、清住雄希、岩槻政晃、長井洋平、吉田直矢、馬場秀夫
- Organizer
  第74回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-17H04273
[Presentation] Fusobacterium nucleatumの食道癌進展への関与とそのメカニズム；腫瘍免疫、NF-kB経路との関連2019
- Author(s)
  野元大地、馬場祥史、秋山貴彦、岡留一雄、山下晃平、坂本悠樹、大徳暢哉、織田枝里、内原智幸、徳永竜馬、原田和人、山村謙介、江藤弘二郎、日吉幸晴、長井洋平、岩槻政晃、石本崇胤、岩上志朗、宮本裕士、吉田直矢、馬場秀夫
- Organizer
  第30回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-17H04273
[Presentation] 食道癌におけるLINE-1メチル化と腫瘍免疫2018
- Author(s)
  馬場祥史、小澄敬祐、岡留一雄、八木泰佑、清住雄希、江藤弘二郎、日吉幸晴、長井洋平、石本崇胤、岩上志朗、宮本裕士、吉田直矢、馬場秀夫
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04273
[Presentation] LINE-1 methylation level and local immune response in esophageal cancer2018
- Author(s)
  Yoshifumi Baba、Keisuke Kosumi, Daichi Nomoto, Kazuo Okadome, Taisuke Yagi, Yuki Kiyozumi, Kojiro Eto, Yukiharu Hiyoshi, Takatsugu Ishimoto, Masaaki Iwatsuki, Shiro Iwagami, Yuji Miyamoto, Naoya Yoshida, Hideo Baba
- Organizer
  The International Society for Disease of the Esophagus(ISDE)
- Data Source
  KAKENHI-PROJECT-17H04273
[Presentation] IDO1 high expression is associated with a poor prognosis in patients with esophageal cancer.2018
- Author(s)
  Yuki Kiyozumi, Yoshifumi Baba, Taisuke Yagi, Yuki Koga, Tomoyuki Uchihara, Daisuke Kuroda, Hiroshi Sawayama, Ryuichi Krashima, Yukiharu Hiyoshi, Takatsugu Ishimoto, Masaaki Iwatsuki, Yuji Miyamoto, Naoya Yoshida, Hideo Baba.
- Organizer
  Association for Cancer Research 2018
- Data Source
  KAKENHI-PROJECT-17K10596
[Presentation] 個別化治療を目指したLINE-1メチル化レベル解析：予後予測、早期診断、免疫チェックポイント阻害剤のbiomarkerとしての可能性2018
- Author(s)
  馬場祥史、岡留一雄、八木泰佑、黒田大介、澤山浩、日吉幸晴、岩槻政晃、石本崇胤、宮本裕士、吉田直矢、馬場秀夫
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17H04273
[Presentation] 腸内細菌 Fusobacterium nucleatumは食道癌に対する化学療法感受性に影響を与える2018
- Author(s)
  馬場祥史、山村謙介、江藤弘二郎、日吉幸晴、長井洋平、岩槻政晃、岩上志朗、宮本裕士、吉田直矢、馬場秀夫
- Organizer
  第56回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04273
[Presentation] The relationship between Microbiome Fusobacterium Nucleatum and autophagy in esophageal cancer.2018
- Author(s)
  Liu Yang, Yoshifumi Baba, Shigeki Nakagawa, Hiroshi Sawayama, Takatsugu Ishimoto, Masaaki Iwatsuki, Yuji Miyamoto, Yoichi Yamashita, Naoya Yoshida, Hideo Baba.
- Organizer
  Association for Cancer Research 2018
- Data Source
  KAKENHI-PROJECT-17K10596
[Presentation] The relationship between Microbiome Fusobacterium Nucleatum and autophagy in esophageal cancer2018
- Author(s)
  Liu Yang, Yoshifumi Baba, Shigeki Nakagawa, Hiroshi Sawayama, Takatsugu Ishimoto, Masaaki Iwatsuki, Yuji Miyamoto , Yoichi Yamashita, Naoya Yoshida, Hideo Baba
- Organizer
  Association for Cancer Research 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04273
[Presentation] GIST における FBXW7 発現と臨床病理学的因子の検討2017
- Author(s)
  古閑　悠輝, 岩槻　政晃, 問端　輔, 内原　智幸, 八木　泰佑, 澤山　浩,日吉　幸晴, 馬場　祥史, 宮本　裕士, 吉田　直矢, 馬場　秀夫
- Organizer
  第28回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-16K10463
[Presentation] The relationship between the expression of F.nucleatumin gastric cancer and clinical characteristics2017
- Author(s)
  織田枝里、馬場祥史、美馬浩介、澤山　浩、木下浩一、岩槻政晃、坂本快郎、吉田直矢、馬場秀夫
- Organizer
  第89回日本胃癌学会総会
- Place of Presentation
  広島国際会議場（広島県）
- Data Source
  KAKENHI-PROJECT-16K10504
[Presentation] GIST における FBXW7、GLUT1 発現と臨床病理学的因子の検討2017
- Author(s)
  古閑　悠輝, 岩槻　政晃, 問端　輔, 内原　智幸,八木　泰佑, 澤山　浩,日吉　幸晴, 馬場　祥史,宮本　裕士,吉田　直矢, 馬場　秀夫
- Organizer
  第76回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10463
[Presentation] The clinicopathological significance of FBXW7 expression in GIST2017
- Author(s)
  Yuki Koga, Masaaki Iwatsuki, Hiroshi Sawayama, Tasuku Toihata, Tomoyuki Uchihara, Yoshifumi Baba, Yasuo Sakamoto, Naoya Yoshida and Hideo Baba
- Organizer
  12th International Gastric Cancer Congress
- Data Source
  KAKENHI-PROJECT-16K10463
[Presentation] GISTにおけるFBXW7発現の臨床的意義2017
- Author(s)
  古閑悠輝、岩槻政晃、澤山浩、問端輔、内原智幸、馬場祥史、坂本快郎、吉田直矢、馬場秀夫
- Organizer
  第89回日本胃癌学会
- Place of Presentation
  広島国際会議場（広島県）
- Data Source
  KAKENHI-PROJECT-16K10463
[Presentation] 胃癌組織におけるFusobacterium nucleatumの検出と臨床病理学的検討2017
- Author(s)
  岩槻政晃、織田枝里、馬場祥史、美馬浩介、山村謙介、澤山　浩、坂本快郎、吉田直矢、馬場秀夫
- Organizer
  第49回胃病態機能研究会
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PROJECT-16K10504
[Presentation] GISTにおけるイマチニブ耐性に関与するmicroRNA-gene pathwayの同定2016
- Author(s)
  岩槻政晃、澤山浩、馬場祥史、坂本快郎、吉田直矢、馬場秀夫
- Organizer
  第27回日本消化器癌発生学会
- Place of Presentation
  城山観光ホテル（鹿児島県）
- Data Source
  KAKENHI-PROJECT-16K10463

1. BABA Yoshifumi (20599708)

# of Collaborated Projects: 5 results

# of Collaborated Products: 46 results
2. IMAMURA Yu (70583045)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. WATANABE Masayuki (80254639)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
4. IWATSUKI Masaaki (50452777)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
5. Nagai Youhei (30551254)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
6. MIYANARI Nobutomo (90336230)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HAYASHI Naoko (20452899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. BABA Hideo (20240905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
9. SAWAYAMA Hiroshi (40594875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
10. 井田智 (80583038)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
11. 石本崇胤 (00594889)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
12. 小澄敬祐 (50594884)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 宮本裕士 (80551259)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
14. 美馬浩介 (00546559)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 澤智裕 (30284756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. 原田和人 (70608869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 山下晃平 (00867202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 江藤弘二郎 (40585717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. Ajani Jaffer A.

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
20. Haraguchi Ikumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. TAKAMORI Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. YAMAMURA Kensuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 藏重淳二

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
24. 森田勝

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
25. 佐伯浩司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 沖英次

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
27. 庄野孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 有馬浩太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 徳永竜馬

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 三森功士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 中尾光善

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 北野雄希

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YOSHIDA NAOYA 吉田 直矢

YOSHIDA Naoya 吉田 直矢

Research Projects

Research Products

Co-Researchers

胃癌腹膜播種における腫瘍不均一性および腫瘍微小環境を標的とした革新的治療法の開発Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

飲酒喫煙が食道癌診療に及ぼすリスクの包括的評価における平均赤血球容積の意義Principal InvestigatorOngoing

Principal Investigator

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Review Section

Research Institution

Investigation of CCN family for development and drug resistance of gastrointestinal cancers

Principal Investigator

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Research Institution

Comprehensive analysis of gut microbiome and epigenetic changes in esophageal cancer.

Principal Investigator

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The identification of molecular markers associated with resistance for molecular targeted agents in GIST

Principal Investigator

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Comprehensive analysis for the association between microbiome in the gastric mucosa and malignant potential of gastric cancerPrincipal Investigator

Principal Investigator

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Research Field

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Tumor-suppressive effects and mechanism of a novel PPAR gamma agonist in esophageal canerPrincipal Investigator

Principal Investigator

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Research Institution

Clinical significance of Laminin-332 and its potential as a therapeutic target

Principal Investigator

Project Period (FY)

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Research Institution

[Journal Article] Mucosal cancer-associated microbes and anastomotic leakage after resection of colorectal carcinoma2020

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DOI

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[Journal Article] Prognostic and clinical impact of PD-L2 and PD-L1 expression in a cohort of 437 oesophageal cancers2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic Nutritional Index, Tumor-infiltrating Lymphocytes, and Prognosis in Patients with Esophageal Cancer2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lysyl oxidase impacts disease outcomes and correlates with global DNA hypomethylation in esophageal cancer2019

Author(s)

Journal Title

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Data Source

[Journal Article] PD-L1 Expression, Tumor-infiltrating Lymphocytes, and Clinical Outcome in Patients With Surgically Resected Esophageal Cancer2019

Author(s)

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[Journal Article] Morphological lymphocytic reaction, patient prognosis and?PD‐1 expression after surgical resection for oesophageal cancer2019

Author(s)

YOSHIDA NAOYA 吉田直矢

YOSHIDA Naoya 吉田直矢