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Ooya Yoshihiro  大矢 佳寛

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Oya Yoshihiro  大矢 佳寛

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Researcher Number 60507218
Other IDs
Affiliation (Current) 2025: 独立行政法人国立病院機構千葉医療センター千葉東病院(臨床研究部), その他部局等, 室長
Affiliation (based on the past Project Information) *help 2025: 独立行政法人国立病院機構千葉医療センター千葉東病院(臨床研究部), その他部局等, 室長
2019 – 2023: 独立行政法人国立病院機構(千葉東病院臨床研究部), その他部局等, 室長
Review Section/Research Field
Principal Investigator
Basic Section 49070:Immunology-related / Basic Section 54020:Connective tissue disease and allergy-related
Keywords
Principal Investigator
リンパ球 / 免疫抑制 / 制御性T細胞 / 免疫 / 樹状細胞 / 移植 / 自己免疫疾患 / 膠原病 / 免疫抑制療法
  • Research Projects

    (3 results)
  • Research Products

    (20 results)
  • Co-Researchers

    (3 People)
  •  ヒト細胞を用いた未同定抗原に対する抗原特異的な免疫抑制療法の開発Principal Investigator

    • Principal Investigator
      大矢 佳寛
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      NHO Chiba Medical Center Chibahigashi National Hospital
  •  関節組織を用いた未同定の抗原に対する抗原特異的免疫療法の開発Principal Investigator

    • Principal Investigator
      大矢 佳寛
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      National Hospital Organization Chiba-East-Hospital
  •  Antigen specific immunosuppression for autoimmune diseasesPrincipal Investigator

    • Principal Investigator
      Oya Yoshihiro
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      National Hospital Organization Chiba-East-Hospital

All 2023 2022 2021 2020 2019

All Journal Article Presentation Patent

  • [Journal Article] Tubulointerstitial nephritis and uveitis syndrome following meningitis and systemic lymphadenopathy with persistent Toxoplasma immunoglobulin M: a case report2021

    • Author(s)
      Yoshihiro Oya, Hidekazu Futami , Takuya Nakazawa , Kazuyuki Ishijima , Keiko Umemiya , Fumiyoshi Takizawa , Naoki Imai , Hiroshi Kitamura , Ryutaro Matsumura
    • Journal Title

      J Med Case Rep.

      Volume: 15 Issue: 1 Pages: 482-496

    • DOI

      10.1186/s13256-021-02909-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07616
  • [Journal Article] T-bet and STAT6 Coordinately Suppress the Development of IL-9-Mediated Atopic Dermatitis-Like Skin Inflammation in Mice2020

    • Author(s)
      Makita S, Takatori H, Matsuki A, Kawashima, Iwata A, Tanaka S, Nakagomi D, Oya Y, Matsumura R, Tamachi T, Suto A, Suzuki K, Hirose K, Nakajima H
    • Journal Title

      J Invest Dermatol.

      Volume: Online ahead of print Issue: 5 Pages: 1274-1285

    • DOI

      10.1016/j.jid.2020.08.029

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08878, KAKENHI-PROJECT-18H02816, KAKENHI-PROJECT-19K17902, KAKENHI-PROJECT-21H02922, KAKENHI-PROJECT-19K07616, KAKENHI-PROJECT-21K08211, KAKENHI-PROJECT-21K08463
  • [Patent] インビトロでの制御性T細胞の特異性評価方法2019

    • Inventor(s)
      大矢 佳寛
    • Industrial Property Rights Holder
      大矢 佳寛
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-19K07616
  • [Patent] インビトロでの制御性T細胞の特異性評価方法2019

    • Inventor(s)
      大矢 佳寛、松村竜太郎
    • Industrial Property Rights Holder
      大矢 佳寛、松村竜太郎
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-19K07616
  • [Presentation] Phenotypic plasticity in suppressive function of dendritic cells mediated by Treg cells2023

    • Author(s)
      Oya Yoshihiro
    • Organizer
      The 52th Annual Meeting of the Japanese Society for Immunology
    • Data Source
      KAKENHI-PROJECT-22K07126
  • [Presentation] Plasticity of DC’s suppressive function and interaction with Treg cells2023

    • Author(s)
      Yoshihiro Oya
    • Organizer
      (FIMSA) Advanced Training Course 2024
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07126
  • [Presentation] Dual function of DC govern the Treg antigen specific suppression2023

    • Author(s)
      Yoshihiro Oya,
    • Organizer
      第72回日本アレルギー学会学術大会
    • Data Source
      KAKENHI-PROJECT-22K07126
  • [Presentation] Foxp3+ Treg educated Dendritic cells have dual function for each different antigen2023

    • Author(s)
      Yoshihiro Oya,
    • Organizer
      第67回日本リウマチ学会総会
    • Data Source
      KAKENHI-PROJECT-22K07126
  • [Presentation] Recruitment of Treg cells by using irrelevant antigen is not enough to suppress T cell response to unknown antigens.2022

    • Author(s)
      Yoshihiro Oya, Hidekazu Futami, Takuya Nakazawa, Ryutaro Matsumura, Hiroshi Nakajima, Ethan Shevach
    • Organizer
      The 66th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology
    • Data Source
      KAKENHI-PROJECT-19K07616
  • [Presentation] DC have dual function of T cell stimulation and T cell suppression for presented each antigen2022

    • Author(s)
      Yoshihiro Oya, Hidekazu Futami, Takuya Nakazawa, Ryutaro Matsumura, Hiroshi Nakajima, Ethan Shevach
    • Organizer
      The 51th Annual Meeting of the Japanese Society for Immunology
    • Data Source
      KAKENHI-PROJECT-19K07616
  • [Presentation] Tubulointerstitial nephritis and uveitis syndrome with persistent Toxoplasma IgM2022

    • Author(s)
      Yoshihiro Oya, Ryutaro Matsumura, Hiroshi Nakajima, Ethan Shevach
    • Organizer
      第50回日本臨床免疫学会総会
    • Data Source
      KAKENHI-PROJECT-19K07616
  • [Presentation] Antigen specific Treg suppression can be mediated just by dendritic cells2021

    • Author(s)
      Yoshihiro Oya, Hidekazu Futami, Takuya Nakazawa, Ryutaro Matsumura, Hiroshi Nakajima, Ethan Shevach
    • Organizer
      The 70th Annual Meeting of Japanese Society of Allergology
    • Data Source
      KAKENHI-PROJECT-19K07616
  • [Presentation] Antigen specific suppression made on DC by Foxp3 Treg is not irreversible2021

    • Author(s)
      Yoshihiro Oya, Hidekazu Futami, Takuya Nakazawa, Ryutaro Matsumura, Hiroshi Nakajima, Ethan Shevach
    • Organizer
      The 65th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology
    • Data Source
      KAKENHI-PROJECT-19K07616
  • [Presentation] Recruitment of Foxp3 Treg is not sufficient to suppress target inflammation2021

    • Author(s)
      Yoshihiro Oya, Ryutaro Matsumura, Hiroshi Nakajima, Ethan Shevach
    • Organizer
      The 50th Annual Meeting of the Japanese Society for Immunology
    • Data Source
      KAKENHI-PROJECT-19K07616
  • [Presentation] Antigen specific suppression can be mediated through Antigen presenting cells in the absence of Treg cells2020

    • Author(s)
      Oya Yoshihiro, Futami Hidekazu, Nakazawa Takuya, Matsumura Ryutaro, Nakajima Hiroshi, Shevach Ethan
    • Organizer
      The 64th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology
    • Data Source
      KAKENHI-PROJECT-19K07616
  • [Presentation] Effector T cells are able to proliferate in the presence of activated non-congnate Foxp3+ Treg cells2020

    • Author(s)
      Oya Yoshihiro, Futami Hidekazu, Nakazawa Takuya, Matsumura Ryutaro, Nakajima Hiroshi, Shevach Ethan
    • Organizer
      JSA/WAO Joint Congress 2020-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07616
  • [Presentation] Antigen-specific Foxp3+ Tregs suppress cognate antigen response but not suppress non-cognate antigen response.2019

    • Author(s)
      Yoshihiro Oya, Hidekazu Futami, Takuya Nakazawa, Ryutaro Matsumura, Hiroshi Nakajima, Ethan Shevach
    • Organizer
      The 63th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology
    • Data Source
      KAKENHI-PROJECT-19K07616
  • [Presentation] Treg mediate antigen specific suppression by capturing peptide-MHC from dendritic cell2019

    • Author(s)
      Yoshihiro Oya
    • Organizer
      The 301st Basic Research Joint Meeting
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07616
  • [Presentation] Foxp3+ Tregs suppress cognate antigen response but not suppress non-cognate antigen response2019

    • Author(s)
      Yoshihiro Oya, Hidekazu Futami, Takuya Nakazawa, Ryutaro Matsumura, Hiroshi Nakajima, Ethan Shevach
    • Organizer
      The 68th Annual Meeting of Japanese Society of Allegology
    • Data Source
      KAKENHI-PROJECT-19K07616
  • [Presentation] Antigen-specific Foxp3+CD4+ Tregs suppress T cell response to cognate antigen but not suppress T cell response to non-cognate antigen in vivo2019

    • Author(s)
      Yoshihiro Oya, Ryutaro Matsumura, Hiroshi Nakajima, Ethan Shevach
    • Organizer
      The 48th Annual Meeting of the Japanese Society for Immunology
    • Data Source
      KAKENHI-PROJECT-19K07616
  • 1.  SUTO Akira
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 2.  SUZUKI Kotaro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  玉地 智宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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