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Ootsu Keishi  大津 圭史

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OTSU Keishi  大津 圭史

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Researcher Number 60509066
Other IDs
Affiliation (Current) 2025: 岩手医科大学, 歯学部, 特任教授
Affiliation (based on the past Project Information) *help 2023 – 2024: 岩手医科大学, 歯学部, 特任教授
2017 – 2022: 岩手医科大学, 歯学部, 准教授
2015 – 2017: 岩手医科大学, 歯学部, 講師
2012 – 2014: 岩手医科大学, 歯学部, 助教
2008 – 2011: Iwate Medical University, 歯学部, ポストドクター
Review Section/Research Field
Principal Investigator
Morphological basic dentistry / Basic Section 57010:Oral biological science-related
Except Principal Investigator
Morphological basic dentistry / Dental engineering/Regenerative dentistry / Basic Section 57040:Regenerative dentistry and dental engineering-related / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords
Principal Investigator
歯 / エナメル質 / エナメル芽細胞 / EMT / Rhoシグナリング / 石灰化 / Rho / Hertwig上皮鞘 / ROCK / 歯根 … More / V-ATPase / リソソーム / プロトンポンプ / エナメル / 成熟期エナメル芽細胞 / リン脂質 / RhoA / 細胞接着 / 細胞極性 / LPA / 脂質 / 恒常性維持 / 上皮間葉転換 / マラッセの上皮遺残 / RhoAシグナル / MET / Hertwig上皮 / 歯根膜 / 恒常性 / 歯周組織 / マラッセ上皮遺残 / HIF1 / 血管 / 血管新生 / 低酸素 / sox2 / slug / Semaphorin / 幹細胞 / 分化 / Hertwig's上皮鞘 / 発生 / slice culture / Rho シグナリング / real time imaging / 歯胚発生 / 象牙芽細胞 / シグナル伝達 / 細胞・組織 / 歯学 / 発生・分化 … More
Except Principal Investigator
再生 / ヘルトビッヒ上皮鞘 / 歯の再生 / iPS細胞 / 歯根膜 / エナメル上皮幹細胞 / 発生 / 上皮間葉転換 / 歯の発生 / HERS / Hertwig上皮鞘 / cementum / regenerative medicine / basement membrane / セメント芽細胞 / チタンインプラント / 歯小嚢細胞 / セメント質再生 / 歯小嚢 / セメント質 / 細胞極性制御 / 象牙質歯髄複合体再生 / 神経堤細胞 / 3Dオルガノイド / 象牙芽細胞分化 / Semaphorin / iPSC / CPNE7 / 極性制御 / ヒトiPS細胞 / 象牙質再生 / Copine-7 / Semaphorin4D / 歯髄再生 / iPS / 象牙質歯髄複合体 / 象牙芽細胞 / Wnt経路 / 阻害剤 / 阻害薬 / 化合物 / Wnt / mTOR / 幹細胞ニッチ / 前駆細胞 / TetOP-H2B-GFPマウス / 静的幹細胞 / 長期ラベル細胞 / 歯髄 / 歯髄幹細胞 / 細胞・組織 / 発生・分化 / プロテオーム / 歯学 / マラッセ残存上皮 / エナメル上皮細胞 / マラッセ上皮遺残 / セマフォリン / 間葉上皮転換 / 細胞周期 / ATP / 組織の保存 / 細胞の保存 / 休眠ホルモン / 切歯歯胚 / マウス切歯 / 外エナメル上皮 / シグナルセンター / 切歯 / 再生医学 / 歯 / 奇形種 / 血管構築 / 星状網 / エナメル器 / 血管新生 / コンディショナルノックアウトマウス / ヘルトヴィッヒ上皮鞘 / タモキシフェン誘導型トランスジェニックマウス / ヘルトビッヒ上皮鞘発達 / Rho-ROCK signaling / 歯根形成 / HERS01a細胞株 / 器官培養 / タモキシフェン誘導型ドミナントネガティブマウス / アクチン / Rho signaling / 細胞遊走 / 臼歯歯根形成 / Biotooth Less
  • Research Projects

    (18 results)
  • Research Products

    (274 results)
  • Co-Researchers

    (19 People)
  •  エナメル質石灰化を制御するプロトンポンプの新たな機能とその破綻による病態の解明Principal Investigator

    • Principal Investigator
      大津 圭史
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57010:Oral biological science-related
    • Research Institution
      Iwate Medical University
  •  セメント芽細胞分化の微小環境の解明とセメント質再生医療の開発

    • Principal Investigator
      原田 英光
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57040:Regenerative dentistry and dental engineering-related
    • Research Institution
      Iwate Medical University
  •  Elucidation of the regulatory mechanism of ameloblasts by lipid mediators and the etiology due to their destruction.Principal Investigator

    • Principal Investigator
      OTSU Keishi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57010:Oral biological science-related
    • Research Institution
      Iwate Medical University
  •  Drug discovery for targeting an mTORC component

    • Principal Investigator
      Nishiya Naoyuki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Iwate Medical University
  •  Is the epithelial rests of Malassez a signal center that controls periodontal tissue homeostasis?Principal Investigator

    • Principal Investigator
      Keishi Otsu
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57010:Oral biological science-related
    • Research Institution
      Iwate Medical University
  •  Regeneration of dentin-pulp complex from iPS cells using new odontoblasts differentiation mechanism and polarity regulation

    • Principal Investigator
      Harada Hidemitsu
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57040:Regenerative dentistry and dental engineering-related
    • Research Institution
      Iwate Medical University
  •  Clarification of the homeostatic mechanism and activation of dental pulp progenitor/quiescent stem cells using proteomic approach

    • Principal Investigator
      Ohshima Hayato
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Niigata University
  •  Approach of production of dental epithelial cells from periodontal ligament mesenchymal cells for tooth regeneration

    • Principal Investigator
      Harada Hidemitsu
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Dental engineering/Regenerative dentistry
    • Research Institution
      Iwate Medical University
  •  Relationship between blood vessels in stellate reticulum and microenvironmental change in ameloblasts differentiationPrincipal Investigator

    • Principal Investigator
      Otsu Keishi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Iwate Medical University
  •  Does a novel signal center exsist at outer enamel epithelium in incisor germ?

    • Principal Investigator
      Harada Hidemitsu
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Iwate Medical University
  •  The development of tissue preservation solution using diapause hormon of insects

    • Principal Investigator
      Kikuchi Kazuko
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Dental engineering/Regenerative dentistry
    • Research Institution
      Iwate Medical University
  •  Relationship between development of Hertwig's epithelial root sheath and molecular mechanism that controls cell migration.

    • Principal Investigator
      FUJIWARA Naoki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Iwate Medical University
  •  Is epithelial-mesenchymal transition of stellate reticulum cells in enamel organ associated with induction of vasculogenesis?

    • Principal Investigator
      HARADA Hidemitsu
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Iwate Medical University
  •  The search for the master regulatory genes for tooth development using iPS cell derived teratomas

    • Principal Investigator
      KIKUCHI KAZUKO
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Iwate Medical University
  •  The role of epithelial-mesenchymal transition in stem cell maintenance via Rho kinasePrincipal Investigator

    • Principal Investigator
      OTSU Keishi
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Iwate Medical University
  •  Clarification of the disintegration of Hertwig's epithelial root sheath by using a real time imagingPrincipal Investigator

    • Principal Investigator
      OTSU Keishi
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Iwate Medical University
  •  Development of technical bases for biotooth formation by using iPS cells

    • Principal Investigator
      FUJIWARA Naoki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dental engineering/Regenerative dentistry
    • Research Institution
      Iwate Medical University
  •  Functional analysis of Rho signaling in morphological change and migration of odontoblastsPrincipal Investigator

    • Principal Investigator
      OTSU Keishi
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (Start-up)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Iwate Medical University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book Patent

  • [Book] Methods Mol Biol.2019

    • Author(s)
      Harada H, Otsu K.
    • Total Pages
      565
    • Publisher
      Humana Press
    • ISBN
      9781493990115
    • Data Source
      KAKENHI-PROJECT-18H02984
  • [Book] iPS細胞から歯原性間葉細胞間葉細胞への分化誘導.再生医療における臨床研究と製品開発2014

    • Author(s)
      大津圭史
    • Publisher
      技術情報協会
    • Data Source
      KAKENHI-PROJECT-24659819
  • [Book] 歯の発生メカニズムと先天性疾患:歯冠の形成異常とそこから見えてくるもの日本歯科評論2014

    • Author(s)
      大津圭史
    • Data Source
      KAKENHI-PROJECT-24791967
  • [Book] 歯の発生メカニズムと先天性疾患:歯根の異常を示す先天性疾患とそのメカニズム 日本歯科評論2014

    • Author(s)
      大津圭史
    • Data Source
      KAKENHI-PROJECT-24791967
  • [Book] 遺伝子医学MOOK 別冊 細胞の3 次元組織化-その最先端技術と材料技術2014

    • Author(s)
      原田英光, 大津圭史
    • Publisher
      株式会社 メディカルドゥ
    • Data Source
      KAKENHI-PROJECT-24791967
  • [Book] 歯の発生メカニズムと先天性疾患:歯の数の異常を考える 日本歯科評論2014

    • Author(s)
      大津圭史
    • Data Source
      KAKENHI-PROJECT-24791967
  • [Book] Organ Cultures and Kidney-Capsule Grafting of tooth germs, Odontogenesis: Methods and Protocols2012

    • Author(s)
      Otsu,K., Fujiwara, N., Harada, H( (Eds; Chrissa Kioussi)
    • Publisher
      Human Press SPRINGER SCIENCE
    • Data Source
      KAKENHI-PROJECT-24659818
  • [Book] iPS細胞から神経堤細胞への分化誘導法の確立2012

    • Author(s)
      大津圭史、藤原尚樹、原田英光
    • Publisher
      DENTAL DIAMOND, 541; 37
    • Data Source
      KAKENHI-PROJECT-24659819
  • [Book] Organ Cultures and Kidney-Capsule Grafting of tooth germs(Eds ; Chrissa Kioussi Odontogenesis)(Methods and Protocols)2012

    • Author(s)
      Keishi Otsu, Naoki Fujiwara, Hidemitsu Harada
    • Publisher
      Human Press SPRINGEE SCIENCE(In press)
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Book] 幹細胞(Stem cell)研究がひらく歯の再生の扉2012

    • Author(s)
      大津圭史、藤原尚樹、原田英光
    • Publisher
      日本歯科評論, 72(8)
    • Data Source
      KAKENHI-PROJECT-24659819
  • [Book] 幹細胞(Stem cell)研究がひらく歯の再生の扉日本歯科評論2012

    • Author(s)
      大津圭史
    • Data Source
      KAKENHI-PROJECT-24791967
  • [Book] Organ Cultures and Kidney-Capsule Grafting of tooth germs

    • Author(s)
      Keishi Otsu, Naoki Fujiwara, Hidemitsu Harada
    • Publisher
      Human Press SPRINGER SCIENCE(in press)
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Book] Organ Cultures and Kidney-Capsule Grafting of tooth germs

    • Author(s)
      Otsu K., et al
    • Publisher
      Human Press SPRINGER SCIENCE(in press)
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Journal Article] LPA6-RhoA signals regulate junctional complexes for polarity and morphology establishment of maturation stage ameloblasts2022

    • Author(s)
      Inaba Akira、Harada Hidemitsu、Ikezaki Shojiro、Kumakami-Sakano Mika、Arai Haruno、Azumane Marii、Ohshima Hayato、Morikawa Kazumasa、Kano Kuniyuki、Aoki Junken、Otsu Keishi
    • Journal Title

      Journal of Oral Biosciences

      Volume: 64 Issue: 1 Pages: 85-92

    • DOI

      10.1016/j.job.2022.01.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K09832, KAKENHI-PROJECT-20K21672, KAKENHI-PROJECT-21K10192
  • [Journal Article] Energy metabolic shift contributes to the phenotype modulation of maturation stage ameloblasts2022

    • Author(s)
      Arai Haruno、Inaba Akira、Ikezaki Shojiro、Kumakami-Sakano Mika、Azumane Marii、Ohshima Hayato、Morikawa Kazumasa、Harada Hidemitsu、Otsu Keishi
    • Journal Title

      Frontiers in Physiology

      Volume: 13 Pages: 1062042-1062042

    • DOI

      10.3389/fphys.2022.1062042

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09832, KAKENHI-PROJECT-21K10192, KAKENHI-PROJECT-22K21021
  • [Journal Article] A novel cyclic peptide (Naturido) modulates glia?neuron interactions in vitro and reverses ageing-related deficits in senescence-accelerated mice2021

    • Author(s)
      Ishiguro Shinichi、Shinada Tetsuro、Wu Zhou、Karimazawa Mayumi、Uchidate Michimasa、Nishimura Eiji、Yasuno Yoko、Ebata Makiko、Sillapakong Piyamas、Ishiguro Hiromi、Ebata Nobuyoshi、Ni Junjun、Jiang Muzhou、Goryo Masanobu、Otsu Keishi、Harada Hidemitsu、Suzuki Koichi
    • Journal Title

      PLOS ONE

      Volume: 16 Issue: 1 Pages: 0245235-0245235

    • DOI

      10.1371/journal.pone.0245235

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09526, KAKENHI-PROJECT-18K09622, KAKENHI-PROJECT-18H02984
  • [Journal Article] Oxygen regulates epithelial stem cell proliferation via RhoA-actomyosin-YAP/TAZ signal in mouse incisor2021

    • Author(s)
      Otsu Keishi、Ida-Yonemochi Hiroko、Ikezaki Shojiro、Ema Masatsugu、Hitomi Jiro、Ohshima Hayato、Harada Hidemitsu
    • Journal Title

      Development

      Volume: 148 Issue: 4

    • DOI

      10.1242/dev.194787

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21672, KAKENHI-PROJECT-18K09526, KAKENHI-PROJECT-18H02984
  • [Journal Article] Lamellarin 14, a derivative of marine alkaloids, inhibits the T790M/C797S mutant epidermal growth factor receptor2021

    • Author(s)
      Nishiya Naoyuki、Oku Yusuke、Ishikawa Chie、Fukuda Tsutomu、Dan Shingo、Mashima Tetsuo、Ushijima Masaru、Furukawa Yoko、Sasaki Yuka、Otsu Keishi、Sakyo Tomoko、Abe Masanori、Yonezawa Honami、Ishibashi Fumito、Matsuura Masaaki、Tomida Akihiro、Seimiya Hiroyuki、Yamori Takao、Iwao Masatomo、Uehara Yoshimasa
    • Journal Title

      Cancer Science

      Volume: - Issue: 5 Pages: 1963-1974

    • DOI

      10.1111/cas.14839

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K05715, KAKENHI-PUBLICLY-20H04789, KAKENHI-PROJECT-18K09526, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20K21555, KAKENHI-PROJECT-19H01806, KAKENHI-PROJECT-19H03523, KAKENHI-PROJECT-19H03526, KAKENHI-PROJECT-21K07251
  • [Journal Article] Mast4 knockout shows the regulation of spermatogonial stem cell self-renewal via the FGF2/ERM pathway2020

    • Author(s)
      Lee Seung-Jun、Park Jinah、Lee Dong-Joon、Otsu Keishi、Kim Pyunggang、Mizuno Seiya、Lee Min-Jung、Kim Hyun-Yi、Harada Hidemitsu、Takahashi Satoru、Kim Seong-Jin、Jung Han-Sung
    • Journal Title

      Cell Death & Differentiation

      Volume: 20 Issue: 5 Pages: 1441-1454

    • DOI

      10.1038/s41418-020-00670-2

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02984, KAKENHI-PROJECT-18K09526
  • [Journal Article] Functional Expression of Sodium-Dependent Glucose Transporter in Amelogenesis.2020

    • Author(s)
      Ida-Yonemochi H, Otsu K, Harada H, Ohshima H.
    • Journal Title

      Journal of Dental Research

      Volume: - Issue: 8 Pages: 1-10

    • DOI

      10.1177/0022034520916130

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09505, KAKENHI-PROJECT-17H04366, KAKENHI-PROJECT-18H02984, KAKENHI-PROJECT-20K21672, KAKENHI-PROJECT-18K09526
  • [Journal Article] Melnick-Needles syndrome associated molecule, Filamin-A regulates dental epithelial cell migration and root formation2020

    • Author(s)
      Hino Ryoko、Yamada Aya、Chiba Yuta、Yoshizaki Keigo、Fukumoto Emiko、Iwamoto Tsutomu、Maruya Yuriko、Otsu Keishi、Harada Hidemistu、Saito Kan、Fukumoto Satoshi
    • Journal Title

      Pediatric Dental Journal

      Volume: 30 Issue: 3 Pages: 208-214

    • DOI

      10.1016/j.pdj.2020.09.003

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K18747, KAKENHI-PROJECT-18H03009, KAKENHI-PROJECT-18H03012, KAKENHI-PROJECT-18K09526
  • [Journal Article] Reduced enamel epithelium-derived cell niche in the junctional epithelium are maintained for a long time in mice2019

    • Author(s)
      Soda M, Saito K, Ida-Yonemochi H, Nakakura-Ohshima K, Kenmotsu S, Ohshima H
    • Journal Title

      J Periodontol

      Volume: Sep 9 Issue: 6 Pages: 819-827

    • DOI

      10.1002/jper.19-0269

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11953, KAKENHI-PROJECT-17H04366, KAKENHI-PROJECT-20K10224, KAKENHI-PROJECT-20K21672
  • [Journal Article] Effective Differentiation of Induced Pluripotent Stem Cells Into Dental Cells.2019

    • Author(s)
      Kim EJ, Yoon KS, Arakaki M, Otsu K, Fukumoto S, Harada H, Green DW, Lee JM, Jung HS.
    • Journal Title

      Dev Dyn

      Volume: Jan;248(1) Issue: 1 Pages: 129-139

    • DOI

      10.1002/dvdy.24663

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K17310, KAKENHI-PROJECT-17H01606, KAKENHI-PROJECT-18H02984, KAKENHI-PROJECT-18K09526
  • [Journal Article] Microdissection and Isolation of Mouse Dental Epithelial Cells of Continuously Growing Mouse Incisors.2019

    • Author(s)
      Harada H, Otsu K.
    • Journal Title

      Methods Mol Biol.

      Volume: 1922 Pages: 3-11

    • DOI

      10.1007/978-1-4939-9012-2_1

    • ISBN
      9781493990115, 9781493990122
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02984
  • [Journal Article] 歯の発生,萌出,乳歯歯根吸収および関連するトピックス2019

    • Author(s)
      原田英光、大津 圭史
    • Journal Title

      小児歯科臨床

      Volume: 24 Pages: 14-19

    • Data Source
      KAKENHI-PROJECT-18H02984
  • [Journal Article] Craniofacial Bone Regeneration using iPS Cell-Derived Neural Crest Like Cells2018

    • Author(s)
      Kikuchi K, Masuda T, Fujiwara N, Kuji A, Miura H, Jung H-S, Harada H, Otsu K.
    • Journal Title

      J. hard tissue biol.

      Volume: 27 Issue: 1 Pages: 1-10

    • DOI

      10.2485/jhtb.27.1

    • NAID

      130006301954

    • ISSN
      1341-7649, 1880-828X
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15813, KAKENHI-PROJECT-18H02984
  • [Journal Article] Msx2 prevents stratified squamous epithelium formation in the enamel organ2018

    • Author(s)
      Nakatomi M, Ida-Yonemochi H, Nakatomi C, Saito K, Kenmotsu S, Maas RL, Ohshima H
    • Journal Title

      J Dent Res

      Volume: 97 Issue: 12 Pages: 1355-1364

    • DOI

      10.1177/0022034518777746

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04366, KAKENHI-PROJECT-17K17082
  • [Journal Article] Evaluation of a new mouse model for studying dental pulpal responses to GaAlAs laser irradiation2017

    • Author(s)
      Sugawara S, Shigetani Y, Kenmotsu S, kiji T, Ohshima H
    • Journal Title

      Journal of Oral Biosciences

      Volume: 59 Issue: 1 Pages: 38-43

    • DOI

      10.1016/j.job.2016.10.002

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26293405, KAKENHI-PROJECT-17H04366
  • [Journal Article] <b>Hertwig’s epithelial root sheath cells contribute to formation of periodontal ligament through epithelial-mesenchymal transition by </b><b>TGF-β </b>2017

    • Author(s)
      Itaya, S., Oka, K., Ogata, K., Tamura, S., Kira-Tatsuoka, M., Fujiwara, N., Otsu, K., Tsuruga, E., Ozaki, M., and Harada, H.
    • Journal Title

      Biomed. Res.

      Volume: 38 Issue: 1 Pages: 61-69

    • DOI

      10.2220/biomedres.38.61

    • NAID

      130005242923

    • ISSN
      0388-6107, 1880-313X
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26670852, KAKENHI-PROJECT-16K20663, KAKENHI-PROJECT-16H05534, KAKENHI-PROJECT-15K15762, KAKENHI-PROJECT-16K15813
  • [Journal Article] The Semaphorin 4D-RhoA-Akt Signal Cascade Regulates Enamel Matrix Secretion in Coordination with Cell Polarization During Ameloblast Differentiation.2016

    • Author(s)
      Otsu K, Ida-Yonemochi H, Fujiwara N, Harada H
    • Journal Title

      J Bone Miner Res

      Volume: 31 Issue: 11 Pages: 1943-1954

    • DOI

      10.1002/jbmr.2876

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462777, KAKENHI-PROJECT-26462794, KAKENHI-PROJECT-16K15813
  • [Journal Article] Sox2 contributes to tooth development via Wnt signaling.2016

    • Author(s)
      Lee MJ, Kim EJ, Otsu K, Harada H, Jung HS
    • Journal Title

      Cell Tissue Res

      Volume: 0 Pages: 0-0

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670805
  • [Journal Article] The glycogen metabolism via Akt signaling is important for the secretion of enamel matrix in tooth development2016

    • Author(s)
      Ida-Yonemochi H, Otsu K, Ohshima H, Harada H
    • Journal Title

      Mech Dev

      Volume: 139 Pages: 18-30

    • DOI

      10.1016/j.mod.2016.01.002

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462777, KAKENHI-PROJECT-26670805
  • [Journal Article] Rho GTPases in ameloblast differentiation.2016

    • Author(s)
      Otsu K, Harada H.
    • Journal Title

      Japanese Dental Science Review.

      Volume: 52(2) Pages: 32-40

    • NAID

      210000179589

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K15813
  • [Journal Article] Live imaging to elucidate cell dynamics in tooth organogenesis and regeneration.2015

    • Author(s)
      Harada H, Kumakami-Sakano M, Fujiwara N, Otsu K.
    • Journal Title

      Journal of Oral Biosciences

      Volume: 57 Issue: 2 Pages: 65-68

    • DOI

      10.1016/j.job.2015.02.005

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26670805
  • [Journal Article] Stem cell sources for tooth regeneration : Current status and future prospects2014

    • Author(s)
      Otsu K, Kumakami-Sakano M, Fujiwara N, Kikuchi K, Keller L, Lesot H, Harada H
    • Journal Title

      Frontiers in Physiology

      Volume: 5 Pages: 36-36

    • DOI

      10.3389/fphys.2014.00036

    • Data Source
      KAKENHI-PROJECT-24659819
  • [Journal Article] Regulatory mechanisms of Hertwigs epithelial root sheath formation and anomaly correlated with root length2014

    • Author(s)
      Kumakami-Sakano, M. Otsu, K. Fujiwara, N. Harada, H.
    • Journal Title

      Exp Cell Res

      Volume: 325 Issue: 2 Pages: 78-82

    • DOI

      10.1016/j.yexcr.2014.02.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24592776, KAKENHI-PROJECT-24791967
  • [Journal Article] The role of Rho-kinase in ameloblast differentiation2013

    • Author(s)
      Otsu K, Sakano M, Masuda T, Fujiwara N, Harada H
    • Journal Title

      Journal of Oral Biosciences

      Volume: 55 Issue: 4 Pages: 159-164

    • DOI

      10.1016/j.job.2013.07.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592776, KAKENHI-PROJECT-24791967
  • [Journal Article] Cell dynamics in cervical loop epithelium during transition from crown to root : implications for Hertwig's epithelial root sheath formation2013

    • Author(s)
      Sakano M, Otsu K, Fujiwara N, Fukumoto S, Yamada A, Harada H
    • Journal Title

      J Periodontal Res

      Volume: 48 Pages: 262-267

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659818
  • [Journal Article] Frontier dental research on iPS cells2013

    • Author(s)
      Arakaki M, Egusa H, Otsu K, Saitoh I, Miura T, Harada H
    • Journal Title

      Journal of Oral Biosciences

      Volume: 55:4 Issue: 4 Pages: 159-164

    • DOI

      10.1016/j.job.2013.08.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659819, KAKENHI-PROJECT-24659858, KAKENHI-PROJECT-25293395, KAKENHI-PROJECT-25293418
  • [Journal Article] Cell dynamics in cervical loop epithelium during transition from crown to root: implications for Hertwig's epithelial root sheath formation.2013

    • Author(s)
      Sakano M, Otsu K, Fujiwara N, Fukumoto S, Yamada A, Harada H
    • Journal Title

      Journal of periodontal Research

      Volume: 48 Issue: 2 Pages: 262-267

    • DOI

      10.1111/jre.12003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592776, KAKENHI-PROJECT-24659818, KAKENHI-PROJECT-24791967
  • [Journal Article] Differentiation of induced pluripotent stem cells into dental mesenchymal cells2012

    • Author(s)
      Otsu, K., Kishigami, R., Oikawa-Sasaki, A., Fukumoto, S., Yamada, A., Fujiwara, N., Ishizeki, K. Harada, H.
    • Journal Title

      Stem Cells & Dev. e-Pub

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Journal Article] Differentiation of induced pluripotent stem cells into dental mesenchymal cells2012

    • Author(s)
      Otsu, K., Kishigami, R., Oikawa-Sasaki, A., Fukumoto, S., Yamada, A., Fujiwara, N., Ishizeki, K. Harada, H.
    • Journal Title

      Stem Cells & Dev

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-22791774
  • [Journal Article] Role of epithelial-stem cell interactions during dental cell differentiation2012

    • Author(s)
      Arakaki M, Ishikawa M, Nakamura T, Iwamoto T, Yamada A, Fukumoto E, Saito M, Otsu K, Harada H, Yamada Y, Fukumoto S
    • Journal Title

      J. Biol. Chem

      Volume: 287 Pages: 10590-10601

    • Data Source
      KAKENHI-PROJECT-22791774
  • [Journal Article] Hepatocyte growth factor stimulates root growth during the development of mouse molar teeth2012

    • Author(s)
      Sakuraba H, Fujiwara N, Sasaki-Oikawa A, Sakano M, Tabata, Y, Otsu K, Ishizeki K, Harada H
    • Journal Title

      J Periodontal Res

      Volume: 47(1) Pages: 81-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659818
  • [Journal Article] Histological analysis of epithelial stem cells during induced pluripotent stem cell-derived teratoma development2012

    • Author(s)
      Kishigami, R., Otsu, K., Oikawa-Sasaki, A., Fujiwara, N., Ishizeki, K., Tabata, Y., Harada, H.
    • Journal Title

      J.Oral Biosci.

      Volume: 54 Pages: 54-58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Journal Article] エナメル質の横紋形成メカニズムの解明2012

    • Author(s)
      及川愛, 大津圭史, 藤原尚樹, 石関清人, 中富満城, 大島勇人, 原田英光
    • Journal Title

      岩医大歯誌

      Volume: 37 Pages: 14-23

    • NAID

      110009445045

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659818
  • [Journal Article] iPS細胞から神経堤細胞への分化誘導法の確立2012

    • Author(s)
      大津圭史, 藤原尚樹, 原田英光
    • Journal Title

      Dental Diamond

      Volume: 37(541) Pages: 92-95

    • Data Source
      KAKENHI-PROJECT-24659818
  • [Journal Article] Histological analysis of epithelial stem cells during induced pluripotent stem cell-derived teratoma development2012

    • Author(s)
      Kishigami, R., Otsu, K., Oikawa-Sasaki, A., Fujiwara, N., Ishizeki, K., Tabata, Y., Harada, H
    • Journal Title

      J. Oral Biosci

      Volume: 54 Pages: 58-65

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659818
  • [Journal Article] Histological analysis of epithelial stem cells during induced pluripotent stem cell-derived teratoma development2012

    • Author(s)
      Kishigami, R., et al
    • Journal Title

      J.Oral Biosci.

      Volume: 54 Issue: 1 Pages: 58-65

    • DOI

      10.1016/j.job.2012.01.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592500, KAKENHI-PROJECT-24659819, KAKENHI-PROJECT-24791967
  • [Journal Article] Role of epithelial-stem cell interactions during dental cell differentiation2012

    • Author(s)
      Arakaki M, Ishikawa M, Nakamura T, Iwamoto T, Yamada A, Fukumoto E, Saito M, Otsu K, Harada H, Yamada Y, Fukumoto S
    • Journal Title

      J Biol Chem

      Volume: 287(13) Issue: 13 Pages: 10590-601

    • DOI

      10.1074/jbc.m111.285874

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659373, KAKENHI-PROJECT-22689053, KAKENHI-PROJECT-22791774, KAKENHI-PROJECT-23390470, KAKENHI-PROJECT-23593013, KAKENHI-PROJECT-23659960, KAKENHI-PROJECT-23659980, KAKENHI-PROJECT-23890022, KAKENHI-PROJECT-24659818, KAKENHI-PROJECT-24791967
  • [Journal Article] エナメル質の横紋形成メカニズムの解明2012

    • Author(s)
      及川愛, 大津圭史, 藤原尚樹, 石関清人, 中富満城, 大島勇人, 原田英光
    • Journal Title

      岩医大歯誌

      Volume: (in press)

    • NAID

      110009445045

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Journal Article] Histological analysis of epithelial stem cells during induced pluripotent stem cell-derived teratoma development2012

    • Author(s)
      Kishigami, R., Otsu, K., Oikawa-Sasaki, A., Fujiwara, N., Ishizeki, K., Tabata, Y., Harada, H.
    • Journal Title

      J. Oral Biosci

      Volume: 54 Pages: 54-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Journal Article] 幹細胞(Stem Cell)研究がひらく歯の再生の扉2012

    • Author(s)
      大津圭史, 藤原尚樹, 原田英光
    • Journal Title

      日本歯科評論

      Volume: 72(8) Pages: 9-11

    • Data Source
      KAKENHI-PROJECT-24659818
  • [Journal Article] エナメル質の横紋形成メカニズムの解明2012

    • Author(s)
      及川愛, 大津圭史, 藤原尚樹, 石関清人, 中富満城, 大島勇人, 原田英光
    • Journal Title

      岩医大歯誌

      Volume: (in press)

    • NAID

      110009445045

    • Data Source
      KAKENHI-PROJECT-22791774
  • [Journal Article] Histological analysis of epithelial stem cells during induced pluripotent stem cell-derived teratoma development2012

    • Author(s)
      Kishigami, R., Otsu, K., Oikawa-Sasaki, A., Fujiwara, N., Ishizeki, K., Tabata, Y., Harada, H.
    • Journal Title

      J. Oral Biosci

      Volume: 54 Pages: 54-58

    • Data Source
      KAKENHI-PROJECT-22791774
  • [Journal Article] iPS細胞から神経堤細胞への分化誘導法の確立2012

    • Author(s)
      大津圭史、藤原尚樹、原田英光
    • Journal Title

      DENTAL DIAMOND

      Volume: 541 Pages: 92-95

    • Data Source
      KAKENHI-PROJECT-24791967
  • [Journal Article] Differentiation of induced pluripotent stem cells into dental mesenchymal cells2012

    • Author(s)
      Otsu K, Kishigami R, Oikawa-Sasaki A, Fukumoto S, Yamada A, Fujiwara N, Ishizeki K, Harada H
    • Journal Title

      Stem Cells Dev

      Volume: 21(7) Pages: 1156-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659818
  • [Journal Article] Role of epithelial-stem cell interactions during dental cell differentiation2012

    • Author(s)
      Arakaki, M., Ishikawa, M., Nakamura, T., Iwamoto, T., Yamada, A., Fukumoto, E., Saito, M., Otsu, K., Harada, H., Yamada, Y., Fukumoto, S.
    • Journal Title

      J. Biol. Chem

      Volume: 287 Pages: 10590-10601

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Journal Article] Role of epithelial-stem cell interactions during dental cell differentiation2012

    • Author(s)
      Arakaki M, Ishikawa M, Nakamura T, Iwamoto T, Yamada A, Fukumoto E, Saito M, Otsu K, Harada H, Yamada Y, Fukumoto S
    • Journal Title

      J Biol Chem

      Volume: 287(13) Pages: 10590-10601

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659818
  • [Journal Article] 幹細胞 (Stem cell) 研究がひらく歯の再生の扉2012

    • Author(s)
      大津圭史、藤原尚樹、原田英光
    • Journal Title

      日本歯科評論

      Volume: 838 Pages: 9-11

    • Data Source
      KAKENHI-PROJECT-24791967
  • [Journal Article] Organ cultures and kidney-capsule grafting of tooth germs.2012

    • Author(s)
      Otsu, K., Fujiwara, N., Harada, H.
    • Journal Title

      Methods Mol Biol.

      Volume: 887 Pages: 59-67

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592776
  • [Journal Article] Establishment of Hertwig's epithelial root sheath cell line from cells invo lved in epithelial-mesenchymal transition2011

    • Author(s)
      Akimoto, T., Fujiwara, N., Kagiya, T., Otsu, K., Ishizeki, K., Harada, H.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 404 Pages: 308-312

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Journal Article] Hepatocyte growth factor stimulates root growth during the development of mouse molar teeth2011

    • Author(s)
      Sakuraba, H., Fujiwara, N., Sasaki-Oikawa, A., Sakano, M., Otsu, K., Ishizeki, K., Harada, H.
    • Journal Title

      J. Period. Res

      Volume: 47 Pages: 81-88

    • Data Source
      KAKENHI-PROJECT-22791774
  • [Journal Article] Functional role of Rho-kinase in ameloblast differentiation2011

    • Author(s)
      Otsu, K., et al
    • Journal Title

      J.Cell Physiol.

      Volume: Vol.226 Issue: 10 Pages: 2527-2534

    • DOI

      10.1002/jcp.22597

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592500, KAKENHI-PROJECT-22791774
  • [Journal Article] Establishment of Hertwig's epithelial root sheath cell line from cells involved in epithelial-mesenchymal transition2011

    • Author(s)
      Akimoto, T., Fujiwara, N., Kagiya, T., Otsu.K., Ishizeki, K., Harada, H.
    • Journal Title

      Biochem.Biophys.Res.Commun.

      Volume: 404 Pages: 308-312

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Journal Article] Establishment of Hertwig's epithelial root sheath cell line from cells involved in epithelial-mesenchymal transition2011

    • Author(s)
      Akimoto, T., Fujiwara, N., Kagiya, T., Otsu, K., Ishizeki, K., Harada, H.
    • Journal Title

      BBRC

      Volume: 404 Pages: 308-312

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Journal Article] Establishment of Hertwig's epithelial root sheath cell line from cells involved in epithelial-mesenchymal transition2011

    • Author(s)
      Akimoto, T., Fujiwara, N., Kagiya, T., Otsu, K., Ishizeki, K., Harada, H.
    • Journal Title

      BBRC

      Volume: 404 Pages: 308-312

    • Data Source
      KAKENHI-PROJECT-22791774
  • [Journal Article] Hepatocyte growth factor stimulates root growth during the development of mouse molar teeth2011

    • Author(s)
      Sakuraba, H., Fujiwara, N., Sasaki-Oikawa, A., Sakano, M., Otsu, K., Ishizeki, K., Harada, H.
    • Journal Title

      J. Period. Res

      Volume: 47 Pages: 81-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Journal Article] Hepatocyte growth factor stimulates root growth during the development of mouse molar teeth2011

    • Author(s)
      Sakuraba, H., Fujiwara, N., Sasaki-Oikawa, A., Sakano, M., Otsu, K., Ishizeki, K., Harada, H.
    • Journal Title

      J.Period.Res.

      Volume: 47 Issue: 1 Pages: 81-88

    • DOI

      10.1111/j.1600-0765.2011.01407.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791774, KAKENHI-PROJECT-24659818
  • [Journal Article] 再生医学に関する新設講義の受講アンケートの結果と考察2011

    • Author(s)
      原田英光, 大津圭史, 藤原尚樹, 石関清人, 及川愛
    • Journal Title

      日歯教誌

      Volume: 27 Pages: 63-68

    • NAID

      10029548262

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Journal Article] Functional role of Rho-kinase in ameloblast differentiation2011

    • Author(s)
      Otsu, K., Kishigami, R., Fujiwara, N., Ishizeki, K., Harada, H
    • Journal Title

      J. Cell Physiol

      Volume: 226 Pages: 2527-2534

    • Data Source
      KAKENHI-PROJECT-22791774
  • [Journal Article] Differentiation of induced pluripotent stem cells into dental mesenchymal cells2011

    • Author(s)
      Otsu, K., et al
    • Journal Title

      Stem Cells Dev.

      Volume: (e-Pub) Issue: 7 Pages: 1156-1164

    • DOI

      10.1089/scd.2011.0210

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592500, KAKENHI-PROJECT-22791774, KAKENHI-PROJECT-23593013, KAKENHI-PROJECT-24390460, KAKENHI-PROJECT-24659819, KAKENHI-PROJECT-24791967
  • [Journal Article] 再生医学に関する新設講義の受講アンケートの結果と考察2011

    • Author(s)
      原田英光, 大津圭史, 藤原尚樹, 石関清人, 及川愛
    • Journal Title

      日歯教誌

      Volume: 27 Pages: 63-68

    • NAID

      10029548262

    • Data Source
      KAKENHI-PROJECT-22791774
  • [Journal Article] Functional role of Rho-kinase in ameloblast differentiation2011

    • Author(s)
      Otsu, K., Kishigami, R., Fujiwara, N., Ishizeki, K., Harada, H.
    • Journal Title

      J. Cell Physiol

      Volume: 226 Pages: 2527-2534

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Journal Article] Functional role of Rho-kinase in ameloblast differentiation.2010

    • Author(s)
      Otsu, K., Kishigami, R., Fujiwara, N., Ishizeki, K., Harada, H.
    • Journal Title

      J.Cell Physiol.

      Volume: (e-pub)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Journal Article] Functional Role of Rho-kinase in Ameloblast Differentiation2010

    • Author(s)
      Keishi Otsu
    • Journal Title

      J.Cell Physiol.

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Journal Article] Concentration-dependent inhibition of angiogenesis by mesenchymal stem cells.2009

    • Author(s)
      Keishi Otsu, Shonit Das, Sandra D. Houser, Sadiqa K. Quadri
    • Journal Title

      Sunita Bhattacharya, Jahar Bhattacharya, Blood 113

      Pages: 4197-4205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890208
  • [Journal Article] Expression of osteogenic proteins during the intrasplenic transplantation of Meckel's chondrocytes : A histochemical and immunohistochemical study2009

    • Author(s)
      石関清人、大津圭史, 他
    • Journal Title

      Arch Histol Cytol 72

      Pages: 1-12

    • NAID

      10025867939

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890208
  • [Journal Article] Expression of osteogenic proteins during the intrasplenic transplantation of Meckel' s chondrocytes: A histochemical and immunohistochemical study2009

    • Author(s)
      Kiyoto Ishizeki, Tadayoshi Kagiya, Naoki Fujiwara, Keishi Otsu, Hidemitsu Harada
    • Journal Title

      Arch Histol Cytol 72

      Pages: 1-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890208
  • [Journal Article] Reduction of Egf signaling decides transition form crown to root in the development of mouse molars2009

    • Author(s)
      Naoki Fujiwara, Tadashi Akimoto, Keishi Otsu, Tadayoshi Kagiya, Kiyoto Ishizeki, Hidemitsu Harada
    • Journal Title

      312B

      Pages: 486-494

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890208
  • [Journal Article] Concentration dependent inhibition of angiogenesis by mesenchymal stem cells2008

    • Author(s)
      Keishi Otsu
    • Journal Title

      Blood (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890208
  • [Patent] 自動培養システム,自動培養方法および抽出物2024

    • Inventor(s)
      片野圭二,上山忠孝,原田英光,池﨑晶二郎,大津圭史
    • Industrial Property Rights Holder
      片野圭二,上山忠孝,原田英光,池﨑晶二郎
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2024-022805
    • Filing Date
      2024
    • Data Source
      KAKENHI-PROJECT-23K27779
  • [Presentation] ヘルトビッヒ上皮鞘は歯小嚢細胞のセメント芽細胞への分化誘導に関わる2024

    • Author(s)
      新藤美湖,池崎晶二郎,大津圭史,加倉加恵,城戸寬史,原田英光.
    • Organizer
      第65回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-23K27779
  • [Presentation] 成熟期エナメル芽細胞の酸性環境構築メカニズムの解明と破骨細胞との比較細胞学2023

    • Author(s)
      大津圭史, 池崎晶二郎, 後藤(松元, 奈緒美, 中西(松井)真弓, 依田浩子, 大島勇人, 原田英光
    • Organizer
      第128回日本解剖学会総会・全国学術集会(招待講演)
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K09832
  • [Presentation] エネルギー代謝シフトによる成熟期エナメル芽細胞フェノタイプ決定2023

    • Author(s)
      大津圭史, 荒井春乃, 稲葉陽, 池崎晶二郎, 熊上-坂野深香, 東根まりい, 森川和政, 原田英光
    • Organizer
      第128回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-21K09832
  • [Presentation] ENVIRONMENTAL OXYGEN REGULATES DENTAL EPITHELIAL STEM CELL PROLIFERATION VIA ENERGY METABOLIC-EPIGENETICS INTERPLAY2023

    • Author(s)
      Keishi Otsu, Shojiro Ikezaki, Hidemitsu Harada
    • Organizer
      ISSCR 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09832
  • [Presentation] Impact of Hypoxia on Slow-Cycling Dental Epithelial Stem Cells: Insights into the Role of Histone Acetylation2023

    • Author(s)
      Keishi Otsu, Shojiro Ikezaki, Hidemitsu Harada
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-21K09832
  • [Presentation] MIHの病因解明に向けた低酸素環境が成熟期エナメル芽細胞に及ぼす影響の解析2022

    • Author(s)
      荒井春乃, 稲葉 陽, 大津圭史, 森川和政
    • Organizer
      第40回日本小児歯科学会北日本地方会
    • Data Source
      KAKENHI-PROJECT-21K09832
  • [Presentation] エナメル芽細胞におけるLPA6シグナルの役割2022

    • Author(s)
      稲葉陽, 池崎晶二郎, 熊上(坂野)深香, 荒井春乃, 東根まりい, 大島勇人, 森川和政, 可野邦行, 青木淳賢, 大津圭史, 原田英光
    • Organizer
      第127回日本解剖学会
    • Data Source
      KAKENHI-PROJECT-21K09832
  • [Presentation] 低酸素環境が成熟期エナメル芽細胞に及ぼす影響2022

    • Author(s)
      荒井春乃, 稲葉陽, 池崎晶二郎, 熊上深香, 東根まりい, 森川和政, 原田英光, 大津圭史
    • Organizer
      第64回歯科基礎医学会
    • Data Source
      KAKENHI-PROJECT-21K09832
  • [Presentation] エナメル質形成におけるカルシウムトランスポーター局在制御メカニズ2021

    • Author(s)
      大津圭史, 稲葉 陽, 池崎晶二郎, 森川和政, 原田英光
    • Organizer
      日本解剖学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02984
  • [Presentation] Regulatory mechanism of dental epithelial stem cells by microenvironmental oxygen-RhoA-YAP/TAZ signal in mouse incisor2021

    • Author(s)
      Keishi Otsu, Hiroko Ida-Yonemochi, Shojiro Ikezaki, Hayato Ohshima, Hidemitsu Harada
    • Organizer
      ISSCR
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02984
  • [Presentation] マウス付着上皮細胞培養法と細胞株樹立2021

    • Author(s)
      池崎昌二郎, 熊上-坂野深香 大津圭史, 原田英光
    • Organizer
      岩手歯学会
    • Data Source
      KAKENHI-PROJECT-18H02984
  • [Presentation] エナメル芽細胞におけるLPAシグナルの機能的役割2020

    • Author(s)
      稲葉陽, 大津圭史, 池崎晶二郎, 荒井春乃, 森川和政, 原田英光
    • Organizer
      第62回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K09526
  • [Presentation] Functional role of LPA signal in ameloblasts2020

    • Author(s)
      稲葉陽,池崎晶二郎,原田英光,森川和政,大津 圭史
    • Organizer
      Japan-Korea joint seminar & Frontier meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09526
  • [Presentation] 成熟期エナメル芽細胞のプロトンポンプの新規機能2020

    • Author(s)
      大津圭史, 池崎晶二郎, 原田英光
    • Organizer
      第62回歯科基礎医学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02984
  • [Presentation] MAST4 regulates spermatogonial stem cell self-renewal through ERM transcription factor2020

    • Author(s)
      Seung-Doo Lee, Keishi Otsu, Dong-Joon Lee, Min-Jung Lee, Pyunggang Kim, Jinah Park, Seong-Jin Kim, Han-Sung Jung
    • Organizer
      Japan-Korea joint seminar & Frontier meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09526
  • [Presentation] マウス付着上皮細胞培養法と細胞株樹立2020

    • Author(s)
      池崎昌二郎,熊上-坂野深香 大津圭史,原田英光
    • Organizer
      第3回岩手県歯科医師会・岩手医科大学歯学会共済シンポジウム 第90回岩手医科大学歯学会例会
    • Data Source
      KAKENHI-PROJECT-18K09526
  • [Presentation] Dysfunction of Rho Signal in Ameloblasts Occurs Amelogenesis Imperfecta and Odontogenic Cysts via EMT2020

    • Author(s)
      原田英光,池崎晶二郎,稲葉陽,大津 圭史
    • Organizer
      Japan-Korea joint seminar & Frontier meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09526
  • [Presentation] Oxygen regulates dental epithelial stem cell proliferation via RhoA-actomyosin-YAP/TAZ signal.2020

    • Author(s)
      Keishi Otsu,Hiroko Ida-Yonemochi,Shojiro Ikezaki,Hayato Ohshima,Hidemitsu Harada
    • Organizer
      2020 ISSCR Virtual
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09526
  • [Presentation] エナメル芽細胞におけるプロトンポンプはナノモーターとして分泌小胞の輸送を担っているか?2020

    • Author(s)
      原田英光、池崎晶二郎、後藤(松元)奈緒美,中西(松井)真弓,和田洋、孫(和田)戈虹、大津圭史
    • Organizer
      第15回ナノバイオメディカル学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02984
  • [Presentation] 成熟期エナメル芽細胞のプロトンポンプの新規機能2020

    • Author(s)
      大津圭史,池崎晶二郎,原田英光
    • Organizer
      第62回歯科基礎医学会学術大会 webセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K09526
  • [Presentation] エナメル芽細胞におけるLPAシグナルの機能的役割2020

    • Author(s)
      稲葉陽,池崎昌二郎,原田英光,大津圭史
    • Organizer
      第125回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-18K09526
  • [Presentation] Oxygen regulates dental epithelial stem cell proliferation via RhoA-actomyosin-YAP/TAZ signal2020

    • Author(s)
      Keishi Otsu, Hiroko Ida-Yonemochi, Shojiro Ikezaki, Hayato Ohshima, Hidemitsu Harada
    • Organizer
      2020 ISSCR
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02984
  • [Presentation] エナメル芽細胞におけるLPAシグナルの機能的役割2020

    • Author(s)
      稲葉陽, 池崎昌二郎, 原田英光, 大津圭史
    • Organizer
      第125回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-18H02984
  • [Presentation] Regulation of dental epithelial stem cell fate decision by hypoxia-RhoA-YAP/TAZ signal.2020

    • Author(s)
      大津 圭史,池崎晶二郎,大島勇人,原田英光
    • Organizer
      Japan-Korea joint seminar & Frontier meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09526
  • [Presentation] エナメル質形成におけるカルシウムトランスポーター局在制御メカニズム2020

    • Author(s)
      大津圭史,稲葉 陽,池崎晶二郎,森川和政,原田英光
    • Organizer
      第126回 日本解剖学会総会・全国学術集会 第98回 日本生理学会大会合同大会 公募シンポジウム Ca2+シグナルの多彩な生理機能細胞内オルガネラから末梢組織、全身まで
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K09526
  • [Presentation] THE HYPOXIC MICROENVIRONMENT MAINTAIN DENTAL EPITHELIAL STEM CELLS VIA RHOA-YAP/TAZ SIGNAL.2019

    • Author(s)
      Keishi Otsu,Shojiro Ikezaki,Hayato Ohshima,Hidemitsu Harada
    • Organizer
      2019 ISSCR/KSSCR International Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09526
  • [Presentation] エナメル上皮幹細胞運命決定機構における低酸素―細胞内シグナル連間2019

    • Author(s)
      大津 圭史, 池崎 昌二郎, 大島勇人, 原田 英光
    • Organizer
      第60回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-18H02984
  • [Presentation] Craniofacial Bone Regeneration using iPS Cell-Derived Neural Crest Like Cells2019

    • Author(s)
      Kazuko Kikuchi,Tomoyuki Masuda,Naoki Fujiwara,Akiyoshi Kuji,Hiroyuki Miura,Han-Sung Jung,Hidemitsu Harada,Keishi Otsu
    • Organizer
      第28回硬組織再生生物学会 学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K09526
  • [Presentation] エナメル上皮幹細胞運命決定機構における低酸素―細胞内シグナル連間2019

    • Author(s)
      大津 圭史,池崎 昌二郎,大島勇人,原田 英光
    • Organizer
      第60回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K09526
  • [Presentation] The impact of microenvironment oxygen level on cell fate decision of dental epithelial stem cells2019

    • Author(s)
      Keishi Otsu,Hayato Ohshima,Hidemitsu Harada
    • Organizer
      The 7th Tripartite Conference on Tooth and Bone in Development & Regeneration
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09526
  • [Presentation] Craniofacial Bone Regeneration using iPS Cell-Derived Neural Crest Like Cells2019

    • Author(s)
      Kazuko Kikuchi, Tomoyuki Masuda, Naoki Fujiwara, Akiyoshi Kuji, Hiroyuki Miura, Han-Sung Jung, Hidemitsu Harada, Keishi Otsu
    • Organizer
      第28回硬組織再生生物学会 学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02984
  • [Presentation] Role of vacuolar proton-pumps (V-ATPase) at maturation stage of amalogenesis2019

    • Author(s)
      Shojiro Ikezaki, Keishi Ots, Naomi Matsumoto, Mayumi Nakanishi-Matsui, Hidemitsu Harada
    • Organizer
      The 2019 TMD (Tooth Morphogenesis & Differentiation) meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02984
  • [Presentation] Nobel role of vacuolar type proton-pump (V-ATPase) at maturation stage of amelogenesis2019

    • Author(s)
      Hidemitsu Harada, Shojiro Ikezaki Keishi Otsu, Naomi Matsumoto, Ge-Hong Sun-Wada, Yoh Wada, Mayumi Nakanishi-Matsui
    • Organizer
      The 7th Tripartite Conference on Tooth and Bone in Development & Regeneration
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02984
  • [Presentation] Nobel role of vacuolar type proton-pump (V-ATPase) at maturation stage of amelogenesis2019

    • Author(s)
      Hidemitsu Harada,Shojiro Ikezaki,Keishi Otsu,Naomi Matsumoto,Ge-Hong,Sun Wada,Yoh Wada,Mayumi Nakanishi-Matsui
    • Organizer
      The 7th Tripartite Conference on Tooth and Bone in Development & Regeneration
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09526
  • [Presentation] Role of vacuolar proton-pumps (V-ATPase) at maturation stage of amalogenesis2019

    • Author(s)
      Shojiro Ikezaki,Keishi Ots,Naomi Matsumoto,Mayumi Nakanishi-Matsui,Hidemitsu Harada
    • Organizer
      The 2019 TMD (Tooth Morphogenesis & Differentiation) meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09526
  • [Presentation] Dental epithelial stem cells are maintained under condition of low oxygen level.2019

    • Author(s)
      Keishi Otsu,Shojiro Ikezaki,Hayato Ohshima,Hidemitsu Harada
    • Organizer
      The 2019 TMD (Tooth Morphogenesis & Differentiation) meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09526
  • [Presentation] Dental epithelial stem cells are maintained under condition of low oxygen level.2019

    • Author(s)
      Keishi Otsu, Shojiro Ikezaki, Hayato Ohshima, Hidemitsu Harada
    • Organizer
      The 2019 TMD (Tooth Morphogenesis & Differentiation) meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02984
  • [Presentation] THE HYPOXIC MICROENVIRONMENT MAINTAIN DENTAL EPITHELIAL STEM CELLS VIA RHOA-YAP/TAZ SIGNAL.2019

    • Author(s)
      Keishi Otsu, Shojiro Ikezaki, Hayato Ohshima, Hidemitsu Harada
    • Organizer
      2019 ISSCR/KSSCR International Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02984
  • [Presentation] LPA6-RhoA signal contributes to ameloblasts differentiation by regulating cell polarity2018

    • Author(s)
      Keishi Otsu, Yoshinori Sahara, Naoyuki Nishiya, Hidemitsu Harada
    • Organizer
      The 6th Tripartite Conference on Tooth and Bone in Development & Regeneration
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02984
  • [Presentation] 成熟期エナメル芽細胞におけるLPAシグナルの役割2018

    • Author(s)
      Keishi Otsu, Mika Kumakami-Sakano, Akira Inaba, Hidemitsu Harada
    • Organizer
      第60回歯科基礎医学会
    • Data Source
      KAKENHI-PROJECT-18H02984
  • [Presentation] Oxygen levels regulate cell fate of mouse dental epithelial stem cells via RhoA signaling2018

    • Author(s)
      Keishi Otsu, Hidemitsu Harada
    • Organizer
      International society for stem cell research (ISSCR) 2018 annual meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09526
  • [Presentation] 組織内酸素濃度応答性RhoA-Sox2シグナルによるエナメル上皮幹細胞制御2018

    • Author(s)
      大津圭史、依田浩子、藤原尚樹、大島勇人、原田英光
    • Organizer
      第123回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-18H02984
  • [Presentation] Oxygen levels regulate cell fate of mouse dental epithelial stem cells via RhoA signaling2018

    • Author(s)
      Keishi Otsu, Hidemitsu Harada
    • Organizer
      International society for stem cell research (ISSCR) 2018 annual meeting
    • Data Source
      KAKENHI-PROJECT-18H02984
  • [Presentation] 酸素濃度依存的Sox2-RhoAシグナルによるエナメル上皮幹細胞制御機構2017

    • Author(s)
      大津圭史,依田浩子,藤原尚樹,大島勇人,原田英光
    • Organizer
      第40回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H04366
  • [Presentation] Hertwig上皮鞘から遊走する細胞動態の解析2017

    • Author(s)
      藤原尚樹、大津圭史、原田英光
    • Organizer
      第59回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-16K15813
  • [Presentation] エナメル芽細胞分化過程におけるAMP-activated protein kinase (AMPK)の発現と機能2017

    • Author(s)
      依田浩子、大津圭史、原田英光、大島勇人
    • Organizer
      第122回 日本解剖学会総会・全国学術大会
    • Data Source
      KAKENHI-PROJECT-16K15813
  • [Presentation] エネルギー代謝を介したエナメル芽細胞分化制御機構2017

    • Author(s)
      大津圭史 藤原尚樹 原田英光
    • Organizer
      第122回 日本解剖学会総会・全国学術大会 シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15813
  • [Presentation] エナメル芽細胞分化過程におけるAMP-activated protein kinase (AMPK)の発現と機能2017

    • Author(s)
      依田浩子、大津圭史、原田英光、大島勇人
    • Organizer
      第122回 日本解剖学会総会・全国学術大会
    • Place of Presentation
      長崎大学坂本キャンパス
    • Data Source
      KAKENHI-PROJECT-26462794
  • [Presentation] 歯根-歯周組織形成を司るヘルトヴィッヒ上皮鞘のダイナミクスと分子制御メカニズム2017

    • Author(s)
      大津圭史、藤原尚樹、原田英光
    • Organizer
      第59回歯科基礎医学会学術大会シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15813
  • [Presentation] 組織内酸素濃度応答性RhoA-Sox2シグナルによるエナメル上皮幹細胞制御2017

    • Author(s)
      大津圭史,依田浩子,藤原尚樹,大島勇人,原田英光
    • Organizer
      第123回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-17H04366
  • [Presentation] 歯の形成過程におけるAMP-activated protein kinase (AMPK)の発現と機能2017

    • Author(s)
      依田浩子、大津圭史、原田英光、大島勇人
    • Organizer
      第59回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-16K15813
  • [Presentation] Dynamics of dental epithelial cells using contact inhibition of locomotion via EMT during tooth root development.2017

    • Author(s)
      Harada H, Otsu K, Fujiwara N.
    • Organizer
      18th International Congress of Developmental Biology
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15813
  • [Presentation] エネルギー代謝を介したエナメル芽細胞分化制御機構2017

    • Author(s)
      大津圭史
    • Organizer
      第122回 日本解剖学会総会・全国学術大会
    • Place of Presentation
      長崎大学坂本キャンパス
    • Invited
    • Data Source
      KAKENHI-PROJECT-26462794
  • [Presentation] 遺伝学的細胞運命マッピングと透明化技術を用いた歯胚3次元イメージング解析2016

    • Author(s)
      高橋 颯、大津 圭史、藤原 尚樹、原田英光
    • Organizer
      第121回日本解剖学会総会・全国学術集会
    • Place of Presentation
      福島
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PROJECT-26462794
  • [Presentation] Semaphorin 4D-RhoA-Akt シグナルはエナメル芽細胞分化において amelogenin 分泌と細胞極性を協調的に制御する2016

    • Author(s)
      大津圭史、依田浩子、藤原尚樹、原田英光
    • Organizer
      第58回歯科基礎医学会学術大会
    • Place of Presentation
      札幌コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-26462794
  • [Presentation] The Semaphorin 4D-RhoA-Akt signal cascade regulates enamel matrix secretion in coordination with cell polarization during ameloblast differentiation2016

    • Author(s)
      Keishi Otsu, Hiroko Ida-Yonemochi, Naoki Fujiwara, Hidemitsu Harada
    • Organizer
      The Tooth Morphogenesis and Differentiation (TMD) 2016
    • Place of Presentation
      Porvoo (Finland)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462794
  • [Presentation] Sema4D-RhoA signaling ensures ameloblast differentiation with a multifunctional regulatory mechanism.2016

    • Author(s)
      Otsu K, Ida-Yonemochi H, Fujiwara N, Harada H.
    • Organizer
      Tripartite Conference on Tooth and Bone; Development & Regeneration.
    • Place of Presentation
      Yantai, China
    • Year and Date
      2016-06-02
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15813
  • [Presentation] Aktシグナルがグルコース代謝を促進しエナメル芽細胞分化を誘導する2015

    • Author(s)
      依田浩子、大津圭史、大島勇人、原田英光
    • Organizer
      第38回日本分子生物学会・第88回日本生化学会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26670805
  • [Presentation] イメージングから考える歯の形態形成機構の新規視点2015

    • Author(s)
      原田英光, 熊上深香,大津圭史, 藤原尚樹
    • Organizer
      第57回歯科基礎医学会
    • Place of Presentation
      新潟
    • Year and Date
      2015-09-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670805
  • [Presentation] イメージングから考える歯の形態形 成機構の新規視点2015

    • Author(s)
      原田英光, 熊上深香,大津圭史, 藤原尚樹
    • Organizer
      第57回歯科基礎医学会学術大会
    • Place of Presentation
      新潟
    • Year and Date
      2015-09-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-26462794
  • [Presentation] Regulation of dental epithelial cell differentiation by Rho signaling2015

    • Author(s)
      Keishi Otsu, Hiroko Ida-Yonemochi, Mika Kumakami-Sakano, Naoki Fujiwara, Hidemitsu Harada
    • Organizer
      The 4th Tripartite Conference on Tooth and Bone
    • Place of Presentation
      成田ビューホテル
    • Year and Date
      2015-06-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462794
  • [Presentation] Regulation of stemness of dental epithelial stem cells by Rho signaling2015

    • Author(s)
      Keishi Otsu, Yusuke Oku, Naoyuki Nishiya, Naoki Fujiwara, Hidemitsu Harada
    • Organizer
      ISSCR 2015 Annual Meeting
    • Place of Presentation
      ストックホルム
    • Year and Date
      2015-06-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462794
  • [Presentation] Regulation of stemness of dental epithelial stem cells by Rho-YAP signaling2015

    • Author(s)
      Keishi Otsu, Yusuke Oku, Naoyuki Nishiya, Naoki Fujiwara, Hidemitsu Harada
    • Organizer
      第57回歯科基礎医学会学術大会
    • Place of Presentation
      新潟
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-26462794
  • [Presentation] Regulation of stemness of dental epithelial stem cells by Rho signaling2015

    • Author(s)
      Otsu K, Oku Y, Nishiya N. Fujiwara N, Harada H
    • Organizer
      ISSCR 2015 Annual Meeting
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2015-06-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670805
  • [Presentation] Differentiation of induced pluripotent stem cells into odontogenic lineage for tooth regeneration2014

    • Author(s)
      Otsu K, Sakano M, Fujiwara N, Harada H
    • Organizer
      Kyudai Oral bioscience
    • Place of Presentation
      Fukuoka
    • Data Source
      KAKENHI-PROJECT-24659819
  • [Presentation] Semaphorin 4D ― Rho Aシグナルによるエナメル芽細胞分化制御2014

    • Author(s)
      大津圭史、熊上-坂野 深香、増田智幸、藤原尚樹、原田英光
    • Organizer
      第56回 歯科基礎医学会学術大会・総会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PROJECT-26462794
  • [Presentation] Differentiation of iPS cells into odontogenic cells2014

    • Author(s)
      Otsu K, Sakano M, Masuda T, Fujiwara N, Harada H
    • Organizer
      CDB symposium 2014 Regeneration of Organs; Programming and Self-organization
    • Place of Presentation
      Kobe
    • Data Source
      KAKENHI-PROJECT-24659819
  • [Presentation] iPS細胞を用いた歯胚組織発生2014

    • Author(s)
      坂野深香、大津圭史、藤原尚樹、原田英光
    • Organizer
      第13回日本再生医療学会総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24659819
  • [Presentation] iPS細胞を用いた歯胚組織再生2013

    • Author(s)
      坂野深香、大津圭史、藤原尚樹、原田英光
    • Organizer
      第55回歯科基礎医学会学術大会・総会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-24659819
  • [Presentation] Role of Rho-GTPase in dental epithelial stem cell.2013

    • Author(s)
      Otsu K, Sakano M, Masuda T, Fujiwara N, Harada H
    • Organizer
      11th International Conference on Tooth Morphogenesis and Differentiation
    • Place of Presentation
      La Londe Les Maures, Feance
    • Data Source
      KAKENHI-PROJECT-24592776
  • [Presentation] エナメル上皮幹細胞におけるRhoシグナリングの役割2013

    • Author(s)
      大津 圭史, 坂野 深香, 増田 智幸, 藤原 尚樹, 原田 英光
    • Organizer
      第118回日本解剖学会総会・学術集会
    • Place of Presentation
      香川大学
    • Data Source
      KAKENHI-PROJECT-24592776
  • [Presentation] Role of Rho-GTPase in dental epithelial stem cell2013

    • Author(s)
      Otsu K, Sakano M, Masuda T, Fujiwara N, Harada H
    • Organizer
      11th International Conference on Tooth Morphogenesis and Differentiation
    • Place of Presentation
      La Londe les Maures, France
    • Data Source
      KAKENHI-PROJECT-24791967
  • [Presentation] Functional role fo Rho signaling in ameloblast differentiation.2013

    • Author(s)
      Otsu K, Sakano M, Masuda T, Fujiwara N, Harada H
    • Organizer
      The Japan-Korea Basic Scientific Cooperation Program 2013 Japan
    • Place of Presentation
      Iwate medical university
    • Data Source
      KAKENHI-PROJECT-24791967
  • [Presentation] iPS細胞における神経堤細胞への分化能2013

    • Author(s)
      大津圭史 坂野深香 増田智幸 藤原尚樹 菊池和子 原田英光
    • Organizer
      第12回日本再生医療学会総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-24791967
  • [Presentation] エナメル上皮幹細胞におけるRho シグナリングの役割2013

    • Author(s)
      大津圭史, 坂野深香, 増田智幸, 藤原尚樹, 原田英光
    • Organizer
      第118回日本解剖学会総会・全国学術集会
    • Place of Presentation
      香川
    • Data Source
      KAKENHI-PROJECT-24791967
  • [Presentation] Differentiation of iPS cells into odonotogenic cells2013

    • Author(s)
      Otsu K, Sakano M, Fujiwara N, Harada H
    • Organizer
      XXIII International Symposium on Morphological Sciences
    • Place of Presentation
      Niigata, Japan
    • Data Source
      KAKENHI-PROJECT-24659819
  • [Presentation] イメージングを駆使した歯の発生の新たな理解への挑戦.2013

    • Author(s)
      原田英光、大津圭史,藤原尚樹,坂野深香
    • Organizer
      第55回歯科基礎医学会学術大会
    • Place of Presentation
      岡山
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659818
  • [Presentation] イメージングを駆使した歯の発生の新たな理解への挑戦2013

    • Author(s)
      原田英光、大津圭史, 藤原尚樹, 坂野深香
    • Organizer
      第55回歯科基礎医学会学術大会・総会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-24659818
  • [Presentation] Cell dynamics in cervical loop epithelium during transition from crown to root: implications for Hertwig’ epithelial root sheath formation.2013

    • Author(s)
      Sakano M, Otsu K, Fujiwara N, Harada H.
    • Organizer
      International Symposium Frontier Meeting, Seoul/Jeonju 2013 Development, Evolution, Taxonomy, and Genetics of Tooth Structure "Tooth Voyage, Up To Date"
    • Place of Presentation
      Jeonju, Korea
    • Data Source
      KAKENHI-PROJECT-24592776
  • [Presentation] Role of Rho signaling during amelogenesis.2013

    • Author(s)
      Harada H, Otsu K, Sakano M, Fujiwara N
    • Organizer
      Tripartite Conference (Korea- Chaina- Japan) on Tooth and Bone; Development & Regeneration" in Seoul, Korea will hold an International Symposium on “Tooth and Bone; Development & Regeneration”
    • Place of Presentation
      Seoul, Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-24592776
  • [Presentation] iPS細胞における神経堤由来細胞への分化能2013

    • Author(s)
      大津圭史 菊池和子 坂野深香 増田智幸 藤原尚樹 原田英光
    • Organizer
      日本再生医療学会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-24659819
  • [Presentation] エナメル上皮幹細胞におけるRhoシグナリングの役割2013

    • Author(s)
      大津圭史、坂野深香、増田智幸、藤原尚樹、原田英光
    • Organizer
      第118回日本解剖学会総会
    • Place of Presentation
      かがわ国際会議場
    • Data Source
      KAKENHI-PROJECT-24791967
  • [Presentation] Stimulation of root formation and regeneration by natural compound.2013

    • Author(s)
      Fujiwara N, Ota M, Sakano M, Otsu K, Woo JT, Harada H
    • Organizer
      11th International Conference on Tooth Morphogenesis and Differentiation
    • Place of Presentation
      La Londe Les Maures, Feance
    • Data Source
      KAKENHI-PROJECT-24592776
  • [Presentation] エナメル上皮幹細胞研究の国際的潮流と今後の展望2013

    • Author(s)
      原田英光, 藤原尚樹, 大津圭史
    • Organizer
      第118回日本解剖学会総会・全国学術集会
    • Place of Presentation
      香川
    • Data Source
      KAKENHI-PROJECT-24791967
  • [Presentation] iPS細胞における神経堤由来細胞への分可能2013

    • Author(s)
      大津圭史、菊池和子、坂野深香、増田智幸、藤原尚樹、原田英光
    • Organizer
      第12回日本再生医療学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24659819
  • [Presentation] Rho シグナリングのエナメル芽細胞分化における役割2013

    • Author(s)
      大津圭史, 藤原尚樹
    • Organizer
      原田英光第55回歯科基礎医学会学術大会・総会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-24791967
  • [Presentation] Functional role fo Rho signaling in ameloblast differentiation2013

    • Author(s)
      Otsu K, Sakano M, Masuda T, Fujiwara N, Harada H
    • Organizer
      The Japan-Korea Basic Scientific Cooperation Program 2013 Japan (Iwate Medical Univ) - (Yonsei Univ) Joint Research Project (JSPS) Seminar
    • Place of Presentation
      Iwate
    • Data Source
      KAKENHI-PROJECT-24791967
  • [Presentation] Introduction-エナメル上皮幹細胞研究の国際的潮流と今後の展望2013

    • Author(s)
      原田英光 藤原尚樹 大津圭史
    • Organizer
      第118回日本解剖学会総会・全国学術集会
    • Place of Presentation
      高松(解剖学雑誌88(Suppl):100,2013)
    • Data Source
      KAKENHI-PROJECT-24659818
  • [Presentation] Role of Rho-GTPase in dental epithelial stem cell2013

    • Author(s)
      Otsu K, Sakano M, Masuda T, Fujiwara N, Harada H
    • Organizer
      11th International Conference on Tooth Morphogenesis and Differentiation
    • Place of Presentation
      France
    • Data Source
      KAKENHI-PROJECT-24791967
  • [Presentation] エナメル上皮幹細胞の分裂後の動態を制御する細胞走化性因子の役割2013

    • Author(s)
      田巻玉器, 大津圭史, 原田英光, 長澤丘司, 入江一元
    • Organizer
      第118回日本解剖学会総会・全国学術集会
    • Place of Presentation
      香川
    • Data Source
      KAKENHI-PROJECT-24791967
  • [Presentation] Cell dynamics in cervical loop epithelium during transition from crown to root : implications for Hertwig' epithelial root sheath formation2013

    • Author(s)
      Sakano, M, Otsu, K., Fujiwara, N., Harada, H
    • Organizer
      International Symposium Frontier Meeting, Seoul/Jeonju 2013 Development, Evolution, Taxonomy, and Genetics of Tooth Structure "Tooth Voyage, Up To Date"
    • Place of Presentation
      Jeonju, Korea
    • Data Source
      KAKENHI-PROJECT-24659818
  • [Presentation] Sternness of dental epithelial stem cells considering feature of dental epithelial cells2013

    • Author(s)
      Harada, H., Otsu, K., Sakano, M., Fujiwara, N
    • Organizer
      International Symposium Frontier Meeting, Seoul/Jeonju 2013 Development, Evolution, Taxonomy, and Genetics of Tooth Structure "Tooth Voyage, Up To Date"
    • Place of Presentation
      Jeonju, Korea
    • Data Source
      KAKENHI-PROJECT-24659818
  • [Presentation] エナメル上皮幹細胞研究の国際的潮流と今後の展望2013

    • Author(s)
      原田 英光,藤原 尚樹,大津 圭史
    • Organizer
      第118回日本解剖学会総会・学術集会
    • Place of Presentation
      香川大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-24592776
  • [Presentation] Role of Rho signaling during amelogenesis. Tripartite Conference (Korea- Chaina- Japan) on Tooth and Bone; Development & Regeneration" in Seoul2013

    • Author(s)
      Harada, H., Otsu, K., Sakano, M., Fujiwara, N
    • Organizer
      Korea will hold an International Symposium on "Tooth and Bone; Development & Regeneration"
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-24659818
  • [Presentation] エナメル芽細胞分化におけるRho-kinaseの役割2012

    • Author(s)
      大津圭史
    • Organizer
      第54回歯科基礎医学会学術大会
    • Place of Presentation
      奥羽大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-24791967
  • [Presentation] The role of Rho signaling pathway in dental epithelial stem cells2012

    • Author(s)
      Keishi Otsu, Hidemitsu Harada
    • Organizer
      Gordon Research Conference, Craniofacial development an regenerative medicine
    • Place of Presentation
      CA, U.S.A
    • Data Source
      KAKENHI-PROJECT-24659818
  • [Presentation] iPS細胞から象牙芽細胞への分化誘導技術の開発と歯の再生への応用2012

    • Author(s)
      大津圭史
    • Organizer
      第54回歯科基礎医学会学術大会ならびに総会、サテライトシンポジウム3「口腔領域におけるips研究の現状と展望」
    • Place of Presentation
      群山
    • Year and Date
      2012-09-14
    • Data Source
      KAKENHI-PROJECT-24659818
  • [Presentation] iPS細胞から象牙芽細胞への分化誘導技術の開発と歯の再生への応用2012

    • Author(s)
      大津圭史
    • Organizer
      第54回歯科基礎医学会学術大会
    • Place of Presentation
      群山
    • Data Source
      KAKENHI-PROJECT-24659819
  • [Presentation] The role of Rho signaling pathway in dental epithelial stem cells.2012

    • Author(s)
      Otsu, K., et al.
    • Organizer
      Gordon Research Conference, Craniofacial development a regenerative medicine
    • Place of Presentation
      CA, U. S. A
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] Hidemitsu Harada The role of Rho signaling pathway in dental epithelial stem cells2012

    • Author(s)
      Keishi Otsu, Ryota Kishigami, Ai Oikawa-Sasaki, Naoki Fujiwara, Kiyoto Ishizeki
    • Organizer
      第117回日本解剖学会総会・全国学術大会
    • Place of Presentation
      山梨大学(山梨)
    • Year and Date
      2012-03-26
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] The role of Rho signaling pathway in dental epithelial stem cells2012

    • Author(s)
      Keishi Otsu, Ryota Kishigami, Ai Oikawa-Sasaki, Naoki Fujiwara, Kiyoto Ishizeki, Hidemitsu Harada
    • Organizer
      第117回日本解剖学会総会・全国学術大会研究集会・懇話会
    • Place of Presentation
      山梨大学(山梨)
    • Year and Date
      2012-03-26
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] ライブイメージングでとらえる歯の発生メカニズム2012

    • Author(s)
      大津圭史, 原田英光
    • Organizer
      第117回日本解剖学会総会・全国学術大会研究集会・懇話会
    • Place of Presentation
      山梨大学(山梨)
    • Year and Date
      2012-03-26
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] ライブイメージングでとらえる歯の発生メカニズム2012

    • Author(s)
      大津圭史
    • Organizer
      第117回日本解剖学会総会・全国学術大会
    • Place of Presentation
      山梨
    • Year and Date
      2012-03-26
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] エナメル芽細胞分化におけるRho-kinase の役割2012

    • Author(s)
      大津圭史
    • Organizer
      第54回歯科基礎医学会学術大会
    • Place of Presentation
      郡山
    • Data Source
      KAKENHI-PROJECT-24791967
  • [Presentation] iPS細胞から象牙芽細胞への分化誘導技術の開発と歯の再生への応用2012

    • Author(s)
      大津圭史
    • Organizer
      第54回歯科基礎医学会学術大会
    • Place of Presentation
      奥羽大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-24791967
  • [Presentation] ライブイメージングでとらえる歯の発生メカニズム2012

    • Author(s)
      大津圭史, 原田英光
    • Organizer
      第117回日本解剖学会総会・全国学術大会研究集会・懇話会
    • Place of Presentation
      山梨大学(山梨)(招待講演)
    • Year and Date
      2012-03-26
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] ライブイメージングでとらえる歯の発生メカニズム2012

    • Author(s)
      大津圭史, ら
    • Organizer
      第117回日本解剖学会総会・全国学術集会サテライトシンポジウム
    • Place of Presentation
      甲府
    • Year and Date
      2012-03-26
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] Adult stem cells versus iPS cells for human tooth regeneration2012

    • Author(s)
      Hidemitsu Harada, Keishi Otsu, NaokiFujiwara
    • Organizer
      2012 International Conference on Tooth and Bone Development and Regeneration
    • Place of Presentation
      Chengdu, China
    • Data Source
      KAKENHI-PROJECT-24659818
  • [Presentation] iPS細胞から歯原性問葉細胞への分化誘導2012

    • Author(s)
      大津圭史, 藤原尚樹, 原田英光
    • Organizer
      第11回再生医療学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24659818
  • [Presentation] The role of Rho signaling pathway in dental epithelial stem cells2012

    • Author(s)
      Keishi Otsu, Hidemitsu Harada
    • Organizer
      Gordon Research Conference, Craniofacial development an regenerative medicine
    • Place of Presentation
      CA, U. S. A
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] The role of Rho signaling pathway in dental epithelial stem cells2012

    • Author(s)
      Keishi Otsu, et al
    • Organizer
      Gordon Research Conference, Craniofacial development an regenerative medicine
    • Place of Presentation
      CA, U.S.A.
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] The role of Rho signaling pathway in dental epithelial stem cells2012

    • Author(s)
      Keishi Otsu, Hidemitsu Harada
    • Organizer
      Gordon Research Conference, Craniofacial development an regenerative medicine
    • Place of Presentation
      CA, U.S.A.
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] 肝細胞増殖因子による歯根形成の誘導2012

    • Author(s)
      藤原尚樹、坂野深香、大津圭史、原田英光
    • Organizer
      第54回歯科基礎医学会学術大会・総会
    • Place of Presentation
      奥羽大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-24592776
  • [Presentation] 天然低分子化合物、ハルミンの歯根形成促進作用2012

    • Author(s)
      藤原尚樹、 大津圭史、坂野深香、太田正人、原田英光
    • Organizer
      第54回歯科基礎医学会学術大会
    • Place of Presentation
      奥羽大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-24791967
  • [Presentation] iPS細胞から歯原性間葉細胞への分化誘導2012

    • Author(s)
      大津圭史、原田英光、藤原尚樹
    • Organizer
      第11回日本再生医療学会総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-24791967
  • [Presentation] The role of Rho signaling pathway in dental epithelial stem cells2012

    • Author(s)
      Keishi Otsu, Hidemitsu Harada
    • Organizer
      Gordon research conferences, Craniofacial morphogenesis & tissue regeneration
    • Place of Presentation
      U.S.A
    • Data Source
      KAKENHI-PROJECT-24791967
  • [Presentation] ライブイメージングでとらえる歯の発生メカニズム2012

    • Author(s)
      大津圭史, 原田英光
    • Organizer
      第117回日本解剖学会総会・全国学術大会研究集会・懇話会歯の発生の会シンポジウム
    • Place of Presentation
      山梨
    • Data Source
      KAKENHI-PROJECT-24659818
  • [Presentation] The role of Rho signaling pathway in dental epithelial stem cells2012

    • Author(s)
      Keishi Otsu, Ryota Kishigami, Ai Oikawa-Sasaki, Naoki Fujiwara, Kiyoto Ishizeki, Hidemitsu Harada
    • Organizer
      第117回日本解剖学会総会・全国学術集会
    • Place of Presentation
      甲府
    • Data Source
      KAKENHI-PROJECT-24791967
  • [Presentation] iPS細胞から歯原性間葉細胞への分化誘導2012

    • Author(s)
      大津圭史、原田英光、藤原尚樹
    • Organizer
      第11回日本再生医療学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24659819
  • [Presentation] Adult stem cells versus iPS cells for human tooth regeneration2012

    • Author(s)
      Hidemitsu Harada, Keishi Otsu, Naoki Fujiwara
    • Organizer
      2012 International Conference on Tooth and Bone Development and Regeneration.
    • Place of Presentation
      Chengdu, China
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659818
  • [Presentation] 天然低分子化合物、ハルミンの歯根形成促進作用2012

    • Author(s)
      藤原 尚樹、大津 圭史、坂野 深香、太田 正人、原田 英光
    • Organizer
      第54回歯科基礎医学会学術大会・総会
    • Place of Presentation
      奥羽大学
    • Data Source
      KAKENHI-PROJECT-24592776
  • [Presentation] 天然低分子化合物、ハルミンの歯根形成促進作用2012

    • Author(s)
      藤原尚樹、大津圭史、坂野深香、太田正人、原田英光
    • Organizer
      第54回歯科基礎医学会学術大会ならびに総会
    • Place of Presentation
      群山
    • Year and Date
      2012-09-16
    • Data Source
      KAKENHI-PROJECT-24659818
  • [Presentation] The role of Rho signaling pathway in dental epithelial stem cells2012

    • Author(s)
      Otsu, K., et al.
    • Organizer
      第117回日本解剖学会総会・全国学術大会
    • Place of Presentation
      山梨
    • Year and Date
      2012-03-26
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] 幹細胞成長因子による歯根形成の誘導2012

    • Author(s)
      藤原尚樹、坂野深香、大津圭史、原田英光
    • Organizer
      第54回歯科基礎医学会学術大会ならびに総会、サテライトシンポジウム3「口腔領域におけるips研究の現状と展望」
    • Place of Presentation
      群山
    • Year and Date
      2012-09-14
    • Data Source
      KAKENHI-PROJECT-24659818
  • [Presentation] The role ofRho signaling pathway in dental epithelial stem cells2012

    • Author(s)
      Keishi Otsu, Ryota Kishigami, Al Oikawa-Sasaki, Naoki Fujiwara, Kiyoto Ishizeki, Hidemitsu Harada
    • Organizer
      117回 日本解剖学会総会・全国学術大会
    • Place of Presentation
      山梨
    • Data Source
      KAKENHI-PROJECT-24659818
  • [Presentation] アメロゲニンの概日的発現周期に関わるMsx2の役割2011

    • Author(s)
      及川愛, 大津圭史, 藤原尚樹, 石関清人, 中冨満城, 大島勇人, 原田英光
    • Organizer
      第53回歯科基礎医学会学術大会・総会
    • Place of Presentation
      長良川国際会議場(岐阜)
    • Year and Date
      2011-09-30
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] Functional role of Rho signaling in dental epithelial stem cells2011

    • Author(s)
      Otsu, K., et al.
    • Organizer
      Gordon Research Conference, Bone and Tooth
    • Place of Presentation
      Les Diablerets, Switzerland
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] Live cell imaging of dental epithelial stem cells2011

    • Author(s)
      Hidemitsu Harada, Keishi Otsu, Naoki Fujiwara, Kiyoto Ishizeki
    • Organizer
      第116回日本解剖学会・全国学術集会
    • Place of Presentation
      横浜、神奈川
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] Functional role of Rho signaling in dental epithelial stem cells2011

    • Author(s)
      Otsu, K
    • Organizer
      Gordon Research Conference, Bone and Tooth
    • Place of Presentation
      Les Diablerets, Switzerland
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] 歯の再生に向けたiPS細胞から歯原性間葉細胞への分化誘導2011

    • Author(s)
      大津圭史
    • Organizer
      第53回歯科基礎医学会学術大会
    • Place of Presentation
      岐阜
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] ツチ骨とキヌタ骨の形成とメッケル軟骨との関連性2011

    • Author(s)
      石関清人, 大津圭史, 藤原尚樹, 原田英光
    • Organizer
      第53回歯科基礎医学会学術大会・総会
    • Year and Date
      2011-09-30
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] 歯の再生に向けたiPS細胞から歯原性間葉細胞への分化誘導2011

    • Author(s)
      大津圭史
    • Organizer
      第53回歯科基礎医学会学術大会
    • Place of Presentation
      長良川国際会議場・岐阜市
    • Year and Date
      2011-10-02
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] ツチ骨とキヌク骨の形成とメッケル軟骨との関連性2011

    • Author(s)
      石関清人, 大津圭史, 藤原尚樹, 原田英光
    • Organizer
      第53回歯科基礎医学会学術大会・総会
    • Place of Presentation
      長良川国際会議場(岐阜)
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] 歯の再生に向けたiPS細胞から歯原性間葉細胞への分化誘導2011

    • Author(s)
      大津圭史, ら
    • Organizer
      第53回歯科基礎医学会学術大会並びに総会
    • Place of Presentation
      岐阜
    • Year and Date
      2011-10-01
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] Neural Crest like Cell from Induced Pluripotent Stem Cells for Tooth Regeneration2011

    • Author(s)
      Otsu, et al.
    • Organizer
      Frontier Meeting2010
    • Place of Presentation
      Tokyo
    • Year and Date
      2011-02-25
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] iPS細胞由来奇形種における上皮細胞の分化解析と歯の再生への可能性2011

    • Author(s)
      岸上良太、大津圭史、藤原尚樹、原田英光
    • Organizer
      第10回日本再生医療学会総会
    • Place of Presentation
      新宿、東京
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] Neural Crest like Cell from Induced Pluripotent Stem Cells for Tooth Regeneration2011

    • Author(s)
      Keishi Otsu, Ryota Kishigami, Naoki Fujiwara, Harumi Mizuki, Hidemitsu Harada
    • Organizer
      Frontier Meeting 2010
    • Place of Presentation
      市ケ谷、東京
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] Establishment of Hertwig's epithelial root sheath cell line from cells involved in epithelial-mesenchymal transition2011

    • Author(s)
      藤原尚樹、大津圭史
    • Organizer
      Frontier Meeting
    • Place of Presentation
      日大会館(東京都)
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] Establishment of Hertwig's epithelial root sheath cell line from cells involved in epithelial-mesenchymal transition2011

    • Author(s)
      Naoki Fujiwara, Ai Sasaki-Oikawa, Keishi Otsu, Hidemitsu Harada
    • Organizer
      Frontier Meeting 2010
    • Place of Presentation
      市ケ谷、東京
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] 歯の再生に向けたiPS細胞から神経堤細胞への分化誘導2011

    • Author(s)
      大津圭史、岸上良太、石関清人、藤原尚樹、原田英光
    • Organizer
      第10回日本再生医療学会総会
    • Place of Presentation
      新宿、東京
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] Hepatocyte growth factorはマウス臼歯歯胚の歯根形成を促進する2011

    • Author(s)
      藤原尚樹, 櫻庭春菜, 坂野深香, 佐々木, 及川愛, 大津圭史, 石関清人, 原田英光
    • Organizer
      第53回歯科基礎医学会学術大会・総会
    • Place of Presentation
      長良川国際会議場(岐阜)
    • Year and Date
      2011-10-01
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] Neural Crest like Cell from Induced Pluripotent Stem Cells for Tooth Regeneration2011

    • Author(s)
      大津圭史
    • Organizer
      Frontier Meeting
    • Place of Presentation
      日大会館(東京都)
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] 歯の再生に向けたiPS細胞から神経堤細胞への分化誘導2011

    • Author(s)
      大津圭史
    • Organizer
      第10回日本再生医療学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-03-01
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] 歯の再生に向けたiPS細胞から歯原性間葉細胞への分化誘導2011

    • Author(s)
      大津圭史
    • Organizer
      第53回歯科基礎医学会学術大会
    • Place of Presentation
      岐阜
    • Year and Date
      2011-10-02
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] Establishment of immortalized Hertwig's epithelial root sheath cells and character of cell line2010

    • Author(s)
      Naoki Fujiwara, Keishi Otsu
    • Organizer
      International Conference on Tooth Morphogenesis and Differentiation
    • Place of Presentation
      Berlin, Germany
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] エナメル横紋形成のメカニズムに関する新規仮説2010

    • Author(s)
      佐々木愛、大津圭史
    • Organizer
      岩手医科大学歯学会第69回例会
    • Place of Presentation
      岩手医大(盛岡)
    • Year and Date
      2010-02-27
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] Role of Rho kinase in amelogenesis2010

    • Author(s)
      Keishi Otsu
    • Organizer
      Gordon Research Conferences
    • Place of Presentation
      ll Ciocco Hotel and Resort, Lucca, Italy
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] PS細胞由来奇形腫における上皮細胞の分化解析と歯の再生への応用2010

    • Author(s)
      岸上良太、大津圭史
    • Organizer
      岩手医科大学歯学会第70回例会
    • Place of Presentation
      岩手医大(盛岡)
    • Year and Date
      2010-07-03
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] Cell culture of human dental epithelium cells and its approach for regenerative dentistry2010

    • Author(s)
      Mayama, H., Fujiwara, N., Sasaki-Oikawa, Ai., Otsu, K., Sakuraba, H., Miura, H., Harada, H.
    • Organizer
      The 10^<th> Tooth Morphogenesis and Differentiation
    • Place of Presentation
      Berlin, Germany
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] Role of Rho kinase in amelogenesis2010

    • Author(s)
      Keishi Otsu
    • Organizer
      Gordon Research Conferences
    • Place of Presentation
      11 Ciocco Hotel and Resort, Lucca, Italy
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] Cell culture of human dental epithelial cells and its approach for regenerative dentistry.2010

    • Author(s)
      Hisayo Mayama, Keishi Otsu
    • Organizer
      International Conference on Tooth Morphogenesis and Differentiation
    • Place of Presentation
      Berlin, Germany
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] Live cell imaging of Hertwig's epithelial root sheath formation process2010

    • Author(s)
      Hidemitsu Harada, Keishi Otsu
    • Organizer
      Gordon Research Conferences
    • Place of Presentation
      ll Ciocco Hotel and Resort, Lucca, Italy
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] Role of Rho kinase in amelogenesis2010

    • Author(s)
      Otsu, K.
    • Organizer
      Gordon Research Conferences
    • Place of Presentation
      ll Ciocco Hotel and Resort, Lucca, Italy
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] Neural crest like cells from induced pluripotent stem cells for tooth regeneration2010

    • Author(s)
      Ryota Kishigami, Keishi Otsu
    • Organizer
      International Conference on Tooth Morphogenesis and Differentiation
    • Place of Presentation
      Berlin, Germany
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] Visualizing cellular dynamics of tooth development2010

    • Author(s)
      Keishi Otsu
    • Organizer
      International Conference on Tooth Morphogenesis and Differentiation
    • Place of Presentation
      Berlin, Germany
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] New hypothesis of cross-striation formation mechanism2010

    • Author(s)
      Sasaki-Oikawa, Ai., Otsu, K., Fujiwara, Xu, L., Taniguchi, A., Harada, H.
    • Organizer
      The 10^<th> Tooth Morphogenesis and Differentiation
    • Place of Presentation
      Berlin, Germany
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] Visualizing cellular dynamics of tooth development2010

    • Author(s)
      Otsu, K., Fujiwara, N., Harada, H.
    • Organizer
      The 10^<th> Tooth Morphogenesis and Differentiation
    • Place of Presentation
      Berlin, Germany
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] Visualizing cellular dynamics of tooth development2010

    • Author(s)
      Otsu, K., et al.
    • Organizer
      The 10^<th> Tooth Morphogenesis and Differentiation
    • Place of Presentation
      Belrin, Germany
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] New hypothesis of cross-striation formation mechanism2010

    • Author(s)
      Ai Sasaki, Keishi Otsu
    • Organizer
      10^<th> International Conference on Tooth Morphogenesis and Differentiation
    • Place of Presentation
      Berlin, Germany
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] Establishment of immortalized Hertwig's epithelial root sheath cells and character of cell line2010

    • Author(s)
      Fujiwara, N., Akimoto, T., Sasaki-Oikawa, Ai., Otsu, K., Mayama H., Harada, H.
    • Organizer
      The 10^<th> Tooth Morphogenesis and Differentiation
    • Place of Presentation
      Berlin, Germany
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] 間葉系幹細胞と血管内皮細胞との相互作用第115回日本解剖学会総会2010

    • Author(s)
      大津圭史、原田英光
    • Organizer
      全国学術集会
    • Place of Presentation
      岩手
    • Year and Date
      2010-03-30
    • Data Source
      KAKENHI-PROJECT-20890208
  • [Presentation] 間葉系幹細胞と血管内皮細胞との相互作用2010

    • Author(s)
      大津圭史
    • Organizer
      第115回日本解剖学会総会・全国学術集会
    • Place of Presentation
      岩手県水産会館
    • Year and Date
      2010-03-30
    • Data Source
      KAKENHI-PROJECT-20890208
  • [Presentation] Hertwig上皮鞘細胞の特性とEMTの可能性2010

    • Author(s)
      藤原尚樹、大津圭史、櫻庭春菜、石関清人、原田英光
    • Organizer
      第51回歯科基礎医学会学術大会
    • Place of Presentation
      船堀、東京
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] ヘルトヴィッヒ上皮鞘形成過程におけるサービカルループでの細胞動態2009

    • Author(s)
      原田英光、大津圭史
    • Organizer
      第51回歯科基礎医学会学術大会
    • Place of Presentation
      朱鷺メッセ
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PROJECT-20890208
  • [Presentation] Rhoキナーゼによるエナメル芽細胞の極性制御機構2009

    • Author(s)
      大津圭史、藤原尚樹、石関清人、鍵谷忠慶、佐々木憲明
    • Organizer
      第51回歯科基礎医学会学術大会
    • Place of Presentation
      新潟
    • Data Source
      KAKENHI-PROJECT-20890208
  • [Presentation] Rhoキナーゼによるエナメル芽細胞の極性制御機構2009

    • Author(s)
      大津圭史
    • Organizer
      第51回歯科基礎医学会医学会学術大会ならびに総会
    • Place of Presentation
      新潟市
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] Stimulation of root formation and regeneration by a natural compound2009

    • Author(s)
      藤原尚樹、大津圭史
    • Organizer
      85^<th>Congress of the European Orthodontic Society
    • Place of Presentation
      Finlandia Hall, Finland
    • Data Source
      KAKENHI-PROJECT-20890208
  • [Presentation] GFPマウスを用いたメッケル軟骨細胞の形質転換のイメージング解析2009

    • Author(s)
      石関清人、大津圭史
    • Organizer
      第51回歯科基礎医学会学術大会
    • Place of Presentation
      朱鷺メッセ
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PROJECT-20890208
  • [Presentation] 歯の再生を目的としたiPS細胞の上皮、間葉細胞への分化誘導と分離培養2009

    • Author(s)
      大津圭史
    • Organizer
      第114回日本解剖学会総会
    • Place of Presentation
      岡山理科大
    • Year and Date
      2009-03-30
    • Data Source
      KAKENHI-PROJECT-20890208
  • [Presentation] 銅イオンのマクロファージへ及ぼす細胞障害作用について2009

    • Author(s)
      鍵谷忠慶、秋元義、大津圭史、藤原尚樹、石関清人、原田英光, 吉田康夫、平雅之
    • Organizer
      第114回日本解剖学会総会・全国学術大会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-20890208
  • [Presentation] GFPマウスを用いたメッケル軟骨細胞の形質転換のイメージング解析2009

    • Author(s)
      石関清人、大津圭史、鍵谷忠慶、藤原尚樹、原田英光
    • Organizer
      第51回歯科基礎医学会学術大会
    • Place of Presentation
      新潟
    • Data Source
      KAKENHI-PROJECT-20890208
  • [Presentation] Rhoキナーゼによるエナメル芽細胞の極性制御機構2009

    • Author(s)
      大津圭史
    • Organizer
      第51回歯科基礎医学会学術大会並びに総会
    • Place of Presentation
      新潟
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] Rhoキナーゼによるエナメル芽細胞の極性制御機構2009

    • Author(s)
      大津圭史
    • Organizer
      第51回歯科基礎医学会学術大会
    • Place of Presentation
      朱鷺メッセ
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PROJECT-20890208
  • [Presentation] 歯の再生を目的としたips細胞の上皮2009

    • Author(s)
      大津圭史、石関清人、鍵谷忠慶、藤原尚樹、原田英光
    • Organizer
      間葉細胞への分化誘導と分離培養第114回日本解剖学会総会・全国学術大会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-20890208
  • [Presentation] iPS細胞を用いた歯の再生の試み2009

    • Author(s)
      大津圭史
    • Organizer
      第2回岩手医科大学歯学部オープン・リサーチ中間発表会
    • Place of Presentation
      盛岡市
    • Year and Date
      2009-07-25
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] 歯胚組織中の細胞動態を観察するためのimaging systemの開発2009

    • Author(s)
      藤原尚樹, 大津圭史
    • Organizer
      第114回日本解剖学会総会
    • Place of Presentation
      岡山理科大
    • Year and Date
      2009-03-28
    • Data Source
      KAKENHI-PROJECT-20890208
  • [Presentation] iPS細胞を用いた歯の再生の試み2009

    • Author(s)
      大津圭史
    • Organizer
      第2回岩手医科大学歯学部オープンリサーチ中間発表
    • Place of Presentation
      盛岡
    • Year and Date
      2009-07-25
    • Data Source
      KAKENHI-PROJECT-21592500
  • [Presentation] ヘルトヴィッヒ上皮鞘形成過程におけるサービカルループでの細胞動態2009

    • Author(s)
      原田英光、石関清人、大津圭史、鍵谷忠慶、藤原尚樹
    • Organizer
      第51回歯科基礎医学会学術大会
    • Place of Presentation
      新潟
    • Data Source
      KAKENHI-PROJECT-20890208
  • [Presentation] 歯胚組織中の細胞動態を観察するためのimaging systemの開発第114回日本解剖学会総会2009

    • Author(s)
      藤原尚樹、大津圭史、秋元義、鍵谷忠慶、石関清人、原田英光
    • Organizer
      全国学術大会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-20890208
  • [Presentation] Stimulation of root formation and regenration by a natural compound2009

    • Author(s)
      Naoki Fujiwara, Keishi Otsu, Hidemitsu Harada
    • Organizer
      85th Congress of ghe European Orthodontic Society
    • Place of Presentation
      Finland
    • Data Source
      KAKENHI-PROJECT-20890208
  • [Presentation] 歯冠から歯根形成への移行過程におけるEGFsignalingの役割2008

    • Author(s)
      藤原尚樹、大津圭史、秋元義、鍵谷忠慶、石関清人、原田英光
    • Organizer
      第50回歯科基礎医学会学術大会
    • Place of Presentation
      昭和大学(東京)
    • Data Source
      KAKENHI-PROJECT-20890208
  • [Presentation] iPS細胞由来奇形腫における上皮細胞の分化解析と歯の再生への可能性

    • Author(s)
      岸上良太、大津圭史
    • Organizer
      第10回日本再生医療学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] 歯の再生に向けたiPS細胞から神経堤細胞への分化誘導

    • Author(s)
      大津圭史
    • Organizer
      第10回日本再生医療学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] マウス臼歯歯根成長におけるRho signaling の役割

    • Author(s)
      藤原 尚樹、熊上 深香、大津 圭史、原田 英光
    • Organizer
      日本解剖学会 第60回東北・北海道連合支部学術集会
    • Place of Presentation
      福島
    • Year and Date
      2014-09-06 – 2014-09-07
    • Data Source
      KAKENHI-PROJECT-24592776
  • [Presentation] マウス臼歯歯根成長におけるRho signaling の役割

    • Author(s)
      藤原尚樹、熊上深香、大津圭史、原田英光
    • Organizer
      日本解剖学会 第60回東北・北海道連合支部学術集会
    • Place of Presentation
      福島学院大学 福島駅前キャンパス
    • Year and Date
      2014-09-06 – 2014-09-07
    • Data Source
      KAKENHI-PROJECT-26462794
  • [Presentation] Role of Semaphorin-Rho signaling in ameloblast differentiation

    • Author(s)
      大津圭史
    • Organizer
      第120回 日本解剖学会総会・全国学術総会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2015-03-20 – 2015-03-22
    • Data Source
      KAKENHI-PROJECT-26462794
  • [Presentation] 歯根発生メカニズムの新規仮説と歯根形態異常

    • Author(s)
      熊上 深香、大津 圭史、藤原 尚樹、原田 英光
    • Organizer
      第56回 歯科基礎医学会学術大会・総会
    • Place of Presentation
      福岡
    • Year and Date
      2014-09-25 – 2014-09-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-24592776
  • [Presentation] Role of Semaphorin-Rho signaling in ameloblast differentiation

    • Author(s)
      Otsu K., Sahara Y., Harada H.
    • Organizer
      EMBO|EMBL Symposium: Epithelia
    • Place of Presentation
      EMBL Heidelberg, Germany
    • Year and Date
      2014-08-27 – 2014-08-30
    • Data Source
      KAKENHI-PROJECT-26462794
  • [Presentation] 歯根発生メカニズムの新規仮説と歯根形態異常

    • Author(s)
      熊上 深香、大津 圭史、藤原 尚樹、原田 英光
    • Organizer
      第56回 歯科基礎医学会学術大会
    • Place of Presentation
      福岡市
    • Year and Date
      2015-09-25 – 2015-09-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670805
  • [Presentation] Live cell imaging of dental epithelial stem cells

    • Author(s)
      原田英光、大津圭史
    • Organizer
      第116回日本解剖学会総会全国学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22791774
  • [Presentation] Semaphorin 4D ― Rho Aシグナルによるエナメル芽細胞分化制御

    • Author(s)
      大津圭史、熊上-坂野 深香、増田智幸、藤原尚樹、原田英光
    • Organizer
      第56回 歯科基礎医学会学術大会・総会
    • Place of Presentation
      福岡
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-24592776
  • [Presentation] Hertwig上皮鞘細胞の特性とEMTの可能性

    • Author(s)
      藤原尚樹, 大津圭史
    • Organizer
      第115回日本解剖学会総会全国学術集会
    • Place of Presentation
      盛岡
    • Data Source
      KAKENHI-PROJECT-22791774
  • 1.  HARADA Hidemitsu (70271210)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 122 results
  • 2.  FUJIWARA Naoki (20190100)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 63 results
  • 3.  Kumakami Mika (30710826)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 4.  池崎 晶二郎 (00849276)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 9 results
  • 5.  IDA Hiroko (60293213)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  KIKUCHI KAZUKO (40326690)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 7.  Nishiya Naoyuki (10286867)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 8.  CHOUSA Naoyuki (80326694)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  ISEKI Sachiko (80251544)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  Ohshima Hayato (70251824)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 11.  下村 淳子 (00386286)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  山本 格 (30092737)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  横山 拓矢 (70772094)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  ARAKAKI Makiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  大島 邦子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  岩本 勉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  米持 浩子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 7 results
  • 18.  千葉 雄太
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  福田 勉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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