Sakane Ayuko 坂根亜由子

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SAKANE Ayuko 坂根亜由子

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Researcher Number	60509777
Other IDs
Affiliation (Current)	2025: 徳島大学, 大学院医歯薬学研究部(医学域), 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 徳島大学, 大学院医歯薬学研究部(医学域), 准教授 2018 – 2019: 徳島大学, 大学院医歯薬学研究部(医学域), 准教授 2017: 徳島大学, 大学院医歯薬学研究部(医学系), 准教授 2016: 徳島大学, 大学院医歯薬学研究部(医学系), 助教 2015: 徳島大学, 大学院医歯薬学研究部, 助教 2012 – 2014: 徳島大学, ヘルスバイオサイエンス研究部, 助教 2008 – 2011: The University of Tokushima, 大学院・ヘルスバイオサイエンス研究部, 助教
Review Section/Research Field	Principal Investigator General medical chemistry / Basic Section 48040:Medical biochemistry-related / Biological Sciences Except Principal Investigator Medium-sized Section 30:Applied physics and engineering and related fields
Keywords	Principal Investigator Rabファミリー低分子量G蛋白質 / 小胞輸送 / Rab13-JRAB系 / 集団的細胞運動 / Disorder領域 / 蛋白質の構造ダイナミクス / アクチン細胞骨格制御 / １分子構造変化 / JRAB １分子構造変化 / 階層的解析 … More / 蛋白質間相互作用 / 1分子構造変化 / JRAB / アクチン細胞骨格の再編成 / 脳の高次構造・機能 / 細胞内小胞輸送 / アクチン細胞骨格 / 神経突起伸長・シナプス形成 / 細胞間接着形成 / エキソサイトーシス / 高次生命機能システム / 脳・神経系 / シナプス形成・成熟 / 高次神経機能獲得 / 脳・神経系形成 / シナプス形戌 / シナプス成熟 / シナプス形成 / 高次神経機能 … More Except Principal Investigator 屈折率センシング / バイオセンシング / 新型コロナウイルス / バイオセンサー / マイクロ光コム / 光コム Less

Ultra-sensitive and rapid detection of emerging and resurging viruses based on biomedical photonics of optical frequency comb
- Principal Investigator
  
  安井武史
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 30:Applied physics and engineering and related fields
- Research Institution
  The University of Tokushima
Role of protein conformational dynamics and disorder regions in the regulation of the actin cytoskeletonPrincipal Investigator
- Principal Investigator
  
  SAKANE Ayuko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  The University of Tokushima
Analysis for conformational change of JRAB regulating collective cell migration; from molecular information to physiological role in mousePrincipal Investigator
- Principal Investigator
  
  SAKANE Ayuko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokushima
Conformational plasticity of single molecule regulates actin cytoskeletal rearrangement leading to dynamics in higher structure and function of brainPrincipal Investigator
- Principal Investigator
  
  SAKANE Ayuko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokushima
集団的細胞運動を支える細胞内小胞輸送とアクチン細胞骨格再編成のクロストーク制御Principal Investigator
- Principal Investigator
  
  坂根亜由子
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokushima
The role of exocytosis in biological functionsPrincipal Investigator
- Principal Investigator
  
  SAKANE Ayuko
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokushima
Synaptic formation and maturation regulated by membrane trafficking leading to higher function of the nervous systemPrincipal Investigator
- Principal Investigator
  
  SAKANE Ayuko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokushima
Regulation of membrane trafficking in synaptic formation and maturation.Principal Investigator
- Principal Investigator
  
  SAKANE Ayuko
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokushima

[Book] Rab3Aと神経可塑性2010
- Author(s)
  坂根亜由子, 他
- Publisher
  生体の科学
- Data Source
  KAKENHI-PROJECT-22790293
[Journal Article] Rapid, high-sensitivity detection of biomolecules using dual-comb biosensing2023
- Author(s)
  Miyamura Shogo、Oe Ryo、Nakahara Takuya、Koresawa Hidenori、Okada Shota、Taue Shuji、Tokizane Yu、Minamikawa Takeo、Yano Taka-Aki、Otsuka Kunihiro、Sakane Ayuko、Sasaki Takuya、Yasutomo Koji、Kajisa Taira、Yasui Takeshi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 14541-14541
- DOI
  10.1038/s41598-023-41436-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15976, KAKENHI-PROJECT-21K06838
[Journal Article] s-Afadin binds to MAGUIN/Cnksr2 and regulates the localization of the AMPA receptor and glutamatergic synaptic response in hippocampal neurons2023
- Author(s)
  Maruo Tomohiko、Mizutani Kiyohito、Miyata Muneaki、Kuriu Toshihiko、Sakakibara Shotaro、Takahashi Hatena、Kida Daichi、Maesaka Kouki、Sugaya Tsukiko、Sakane Ayuko、Sasaki Takuya、Takai Yoshimi、Mandai Kenji
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299(4) Issue: 4 Pages: 103040-103040
- DOI
  10.1016/j.jbc.2023.103040
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07057, KAKENHI-PROJECT-20K15793, KAKENHI-PROJECT-21K06177, KAKENHI-PROJECT-21K06838
[Journal Article] Highly sensitive detection of nucleocapsid protein from SARS-CoV-2 using a near-infrared surface plasmon resonance sensing system2022
- Author(s)
  Kajisa Taira、Yano Taka-aki、Koresawa Hidenori、Otsuka Kunihiro、Sakane Ayuko、Sasaki Takuya、Yasutomo Koji、Yasui Takeshi
- Journal Title
  
  Optics Continuum
  
  Volume: 1 Issue: 11 Pages: 2336-2336
- DOI
  10.1364/optcon.472486
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20J23577, KAKENHI-PROJECT-20K18479, KAKENHI-PROJECT-22H00303
[Journal Article] JRAB/MICAL-L2 undergoes liquid-liquid phase separation to form tubular recycling endosomes2021
- Author(s)
  Sakane Ayuko、Yano Taka-aki、Uchihashi Takayuki、Horikawa Kazuki、Hara Yusuke、Imoto Issei、Kurisu Shusaku、Yamada Hiroshi、Takei Kohji、Sasaki Takuya
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 551-551
- DOI
  10.1038/s42003-021-02080-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07084, KAKENHI-PROJECT-18H02894, KAKENHI-PLANNED-18H05415, KAKENHI-PUBLICLY-20H04669, KAKENHI-PUBLICLY-21H00393, KAKENHI-PROJECT-21H01772, KAKENHI-PROJECT-20K08591, KAKENHI-PROJECT-21K06838
[Journal Article] Afadin regulates actomyosin organization through αE-catenin at adherens junctions.2020
- Author(s)
  Sakakibara S, Mizutani K, Sugiura A, Sakane A, Sasaki T, Yonemura S, Takai Y.
- Journal Title
  
  J Cell Biol.
  
  Volume: 219 Issue: 5
- DOI
  10.1083/jcb.201907079
- NAID
  120007132269
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08636, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-20K15793, KAKENHI-PROJECT-18H02617
[Journal Article] Actin Cytoskeletal Reorganization Function of JRAB/MICAL-L2 Is Fine-tuned by Intramolecular Interaction between First LIM Zinc Finger and C-terminal Coiled-coil Domains.2019
- Author(s)
  Miyake K, Sakane A, Tsuchiya Y, Sagawa I, Tomida Y, Kasahara J, Imoto I, Watanabe S, Higo D, Mizuguchi K, Sasaki T.
- Journal Title
  
  Sci Rep.
  
  Volume: 9 Issue: 1 Pages: 12794-12794
- DOI
  10.1038/s41598-019-49232-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08636, KAKENHI-PROJECT-18H02894
[Journal Article] Protein kinase C iota facilitates insulin-induced glucose transport by phosphorylation of soluble nSF attachment protein receptor regulator (SNARE) double C2 domain protein b.2018
- Author(s)
  Nomiyama R, Emoto M, Fukuda N, Matsui K, Kondo M, Sakane A, Sasaki T, Tanizawa Y.
- Journal Title
  
  J. Diabetes Investig.
  
  Volume: - Issue: 3 Pages: 1-11
- DOI
  10.1111/jdi.12965
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08636
[Journal Article] Dancing Styles of Collective Cell Migration: Image-Based Computational Analysis of JRAB/MICAL-L2.2018
- Author(s)
  Sakane A., Yoshizawa, S., Yokota, H. and Sasaki, T.
- Journal Title
  
  Front. Cell Dev. Biol.
  
  Volume: 6 Pages: 1-7
- DOI
  10.3389/fcell.2018.00004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08636, KAKENHI-PROJECT-16K15019, KAKENHI-PLANNED-15H05954
[Journal Article] Conformational Plasticity of JRAB/MICAL-L2 Provides 'Law and Order'2016
- Author(s)
  A. Sakane, S. Yoshizawa, M. Nishimura, Y. Tsuchiya, N. Matsushita, K. Miyake, K. Horikawa, I. Imoto, C. Mizuguchi, H. Saito, T. Ueno, S. Matsushita, H. Haga, S. Deguchi, K. Mizuguchi, H.
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: 27 Issue: 20 Pages: 3095-3108
- DOI
  10.1091/mbc.e16-05-0332
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05858, KAKENHI-PLANNED-15H05954, KAKENHI-PROJECT-15H03004, KAKENHI-PROJECT-16J01828, KAKENHI-PROJECT-25293006, KAKENHI-PROJECT-26430104, KAKENHI-PROJECT-26460370, KAKENHI-PROJECT-15K15084, KAKENHI-PROJECT-16K12872, KAKENHI-INTERNATIONAL-15K21726, KAKENHI-ORGANIZER-15H05856
[Journal Article] Roles of Rab family small G proteins in formation of the apical junctional complex in epithelial cells2015
- Author(s)
  Sakane, A. and Sasaki, T.
- Journal Title
  
  Cell Polarity: Biological Role and Basic Mechanisms
  
  Volume: 1 Pages: 349-374
- DOI
  10.1007/978-3-319-14463-4_15
- ISBN
  9783319144627, 9783319144634
- Data Source
  KAKENHI-PUBLICLY-25111723, KAKENHI-PROJECT-26460370, KAKENHI-PROJECT-15K15084
[Journal Article] Roles of Rab family small G proteins in formation of the apical junctional complex in epithelial cells2014
- Author(s)
  Sakane, A. and Sasaki, T.
- Journal Title
  
  Cell Polarity: Biological Role and Basic Mechanisms
  
  Volume: 1
- Data Source
  KAKENHI-PROJECT-24790285
[Journal Article] Roles of Rab family small G proteins in formation of the apical junctional complex in epithelial cells Cell Polarity2014
- Author(s)
  Sakane A, and Sasaki T
- Journal Title
  
  Biological Role and Basic Mechanisms
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-24790285
[Journal Article] Junctional Rab13-binding protein (JRAB) re requires cell spreading via filamins.2013
- Author(s)
  Sakane, A
- Journal Title
  
  Genes Cells
  
  Volume: 18 Issue: 9 Pages: 810-822
- DOI
  10.1111/gtc.12078
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-23390325, KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-24790285, KAKENHI-PUBLICLY-25111723, KAKENHI-PROJECT-25670868
[Journal Article] Expression of RASSF6 in kidney and the implication of RASSF6 and the Hippo pathway in the sorbitol-induced apoptosis in renal proximal tubular epithelial cells2012
- Author(s)
  Withanage, K., Nakagawa, K., Ikeda, M., Kurihara, H., Kudo, T., Yang, Z., Sakane, A., Sasaki, T. and Hata, Y
- Journal Title
  
  J. Biochem
  
  Volume: 152(1) Issue: 1 Pages: 111-119
- DOI
  10.1093/jb/mvs056
- NAID
  10031166119
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20113004, KAKENHI-PROJECT-21390082, KAKENHI-PROJECT-22790275, KAKENHI-PROJECT-22790293, KAKENHI-PROJECT-23790325, KAKENHI-PROJECT-24591214, KAKENHI-PROJECT-24790285
[Journal Article] Rab13 small G protein and Junctional Rab13-binding protein(JRAB) orchestrate actin cytoskeletal organization during epithelial junctional development.2012
- Author(s)
  Sakane, A. et al.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 287 Pages: 42455-42468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790285
[Journal Article] Rab13 small G protein and Junctional Rab13-binding protein (JRAB) orchestrate actin cytoskeletal organization during epithelial Junctional development2012
- Author(s)
  Sakane, A., Abdallah, A.A.M., Nakano, K., Honda, K., Ikeda, W., Nishikawa, Y., Matsumoto, M., Matsushita, N., Kitamura. T., and Sasaki, T
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287(51) Issue: 51 Pages: 42455-424680
- DOI
  10.1074/jbc.m112.383653
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20113004, KAKENHI-PROJECT-22790931, KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-24790285
[Journal Article] Rab13 regulates neurite outgrowth in PC12 cells through its effector protein, JRAB/MICAL-L2.2010
- Author(s)
  Sakane A., et al.
- Journal Title
  
  Mol.Cell.Biol.
  
  Volume: 30 Pages: 1077-1087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790293
[Journal Article] Rab13 regulates neurite outgrowth in PC12 cells through its effector protein, JRAB/MICAL-L2.2010
- Author(s)
  Sakane A., et al.
- Journal Title
  
  Mol.Cell.Biol. 30
  
  Pages: 1077-1087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890149
[Journal Article] Rab13 regulates neurite outgrowth in PC12 cells through its effector protein, JRAB/MICAL-L22010
- Author(s)
  Sakane, A., Honda, K. and Sasaki, T
- Journal Title
  
  Mol. Cell. Biol
  
  Volume: 30(4) Issue: 4 Pages: 1077-1087
- DOI
  10.1128/mcb.01067-09
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20113004, KAKENHI-PROJECT-21390082, KAKENHI-PROJECT-22790293
[Journal Article] Rab13 regulates neurite outgrowth in PC12 cells through its effector protein2010
- Author(s)
  Sakane A., Honda K., Sasaki, T.
- Journal Title
  
  JRAB/MICAL-L2. Mol. Cell Biol. 30(4)
  
  Pages: 1077-1087
- Data Source
  KAKENHI-PROJECT-20890149
[Journal Article] Rubicon and PLEKHM1 negatively regulate the endocytic/autophagic pathway via a novel Rab7-binding domain2010
- Author(s)
  Tabata, K., Matsunaga, K., Sakane, A., Sasaki, T., Noda, T. and Yoshimori, T
- Journal Title
  
  Mol. Biol. Cell
  
  Volume: 21(23) Issue: 23 Pages: 4162-4173
- DOI
  10.1091/mbc.e10-06-0495
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20113004, KAKENHI-PROJECT-21390082, KAKENHI-PROJECT-22790293
[Journal Article] APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle.2009
- Author(s)
  Szodorai, A., Kuan, Y-H., Hunzelmann, S., Engel, U., Sakane, A., Sasaki, T., Takai Y., Kirsch, J., Moller, U., Beyreuther, K., Brady, S., Morfini, G., Kins, S.
- Journal Title
  
  J. Neurosci. 29(46)
  
  Pages: 14534-14544
- Data Source
  KAKENHI-PROJECT-20890149
[Journal Article] 佐々木卓也RabファミリーSmallGタンパク質による小胞輸送制御と高次生命機能2009
- Author(s)
  坂根亜由子
- Journal Title
  
  細胞工学 28巻12号
  
  Pages: 1247-1251
- Data Source
  KAKENHI-PROJECT-20890149
[Journal Article] RabファミリーSmall Gタンパク質による小胞輸送制御と高次生命機能2009
- Author(s)
  坂根亜由子, 他
- Journal Title
  
  細胞工学 28巻
  
  Pages: 1247-1251
- Data Source
  KAKENHI-PROJECT-20890149
[Journal Article] 高次機能システムを支えるエキソサイトーシス系Rabファミリー低分子量GTPase2008
- Author(s)
  坂根亜由子, 他
- Journal Title
  
  蛋白質核酸酵素 53
  
  Pages: 2130-2135
- Data Source
  KAKENHI-PROJECT-20890149
[Journal Article] Analysis on the emerging role of Rab3 GTPase-activating protein in Warburg Micro and Martsolf syndrome.2008
- Author(s)
  Sakane, A., et al.
- Journal Title
  
  Methods Enzymol. 438
  
  Pages: 131-139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890149
[Journal Article] Doc2αand Munc13-4 regulate Ca2+-dependent secretory lysosome exocytosis in mast cells.2008
- Author(s)
  Higashio, H., Nishimura, N., Ishizaki, H., Miyoshi, J., Orita, S., Sakane, A., Sasaki, T.
- Journal Title
  
  J. Immunol. 180(7)
  
  Pages: 4774-4784
- Data Source
  KAKENHI-PROJECT-20890149
[Journal Article] 佐々木卓也高次機能システムを支えるエキソサイトーシス系Rabファミリー低分子量2008
- Author(s)
  坂根亜由子
- Journal Title
  
  GTPase蛋白質核酸酵素 53巻16号
  
  Pages: 2130-2135
- Data Source
  KAKENHI-PROJECT-20890149
[Journal Article] Analysis on the emerging role of Rab3 GTPase-activating protein in Warburg Micro and Martsolf syndrome.2008
- Author(s)
  Sakane. A., Miyoshi, S., Takai, Y., Sasaki, T.
- Journal Title
  
  Methods Enzyntol. 438
  
  Pages: 131-139
- Data Source
  KAKENHI-PROJECT-20890149
[Presentation] デュアル光コムバイオセンシングによるSARS-CoV-2/NP抗原の迅速・高感度検出2023
- Author(s)
  宮村祥吾、麻植凌、仲原拓弥、岡田昇太、田上周路、時実悠、南川丈夫、矢野隆章、大塚邦紘、坂根亜由子、佐々木卓也、安友康二、加治佐平、安井武史
- Organizer
  レーザー学会学術講演会第43回年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-22H00303
[Presentation] The role and significance of JRAB/MICAL-L2-mediated molecular complex formation and dissociation in the regulation of membrane structure and function2022
- Author(s)
  坂根亜由子、佐々木卓也
- Organizer
  第45回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06838
[Presentation] 新型コロナウイルスNタンパク抗原のデュアル光コム・バイオセンシング2022
- Author(s)
  宮村祥吾、麻植凌、仲原拓弥、岡田昇太、加治佐平、時実悠、南川丈夫、矢野隆章、田上周路、大塚邦紘、坂根亜由子、佐々木卓也、安友康二、安井武史
- Organizer
  第83回応用物理学会秋季学術講演会
- Data Source
  KAKENHI-PROJECT-22H00303
[Presentation] Rapid detection of SARS- CoV-2 nucleocapsid protein antigen by dual- comb biosensing2022
- Author(s)
  S. Miyamura, R. Oe, T. Nakahara, S. Okada, S. Taue, Y. Tokizane, T. Minamikawa, T. Yano, K. Otsuka, A. Sakane, T. Sasaki, K. Yasutomo, T. Kajisa, and T. Yasui
- Organizer
  SPIE Biomedical Imaging and Sensing Conference 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00303
[Presentation] Dual-Comb Biosensing for Rapid Detection of SARS-CoV-22022
- Author(s)
  S. Miyamura, R. Oe, T. Nakahara, S. Okada, T. Kajisa, S. Taue, Y. Tokizane, T. Minamikawa, T. Yano, K. Otsuka, A. Sakane, T. Sasaki, K. Yasutomo, and T. Yasui
- Organizer
  Conference on Lasers and Electro-Optics 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00303
[Presentation] 多彩な細胞機能を構造生物学から解く-前説も兼ねて2019
- Author(s)
  坂根亜由子, 土屋裕子, 水口賢司, 佐々木卓也
- Organizer
  第19回日本蛋白質科学会年会・第71回日本細胞生物学会大会合同年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08636
[Presentation] 分子内結合が調節するJRABのLIMドメインによるアクチン細胞骨格の再編成2019
- Author(s)
  富田陽子, 坂根亜由子, 三宅一央, 土屋裕子, 佐川幾子, 笠原二郎, 水口賢司, 佐々木卓也
- Organizer
  第60回日本生化学会中国・四国支部例会
- Data Source
  KAKENHI-PROJECT-17K08636
[Presentation] 集団的細胞運動において一分子構造変化が生み出す多様な運動様式とその役割2018
- Author(s)
  坂根亜由子、吉澤信、土屋裕子、松井翼、出口真次、水口賢司、横田秀夫、佐々木卓也
- Organizer
  第41回日本分子生物学会年会ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-17K08636
[Presentation] 組織構築・修復過程において1分子構造変化が生み出す多彩な細胞移動とその意義2018
- Author(s)
  坂根亜由子、吉澤信、松井翼、土屋裕子、水口賢司、出口真次、横田秀夫、佐々木卓也
- Organizer
  第91回日本生化学会大会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K08636
[Presentation] 異なるRabとエフェクター蛋白質JRABが導く多彩な細胞機能2018
- Author(s)
  土屋裕子、坂根亜由子、佐々木卓也、水口賢司
- Organizer
  第18回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-17K08636
[Presentation] 集団的細胞運動においてRab13-JRAB系がつくりだす秩序と法則性2014
- Author(s)
  坂根亜由子、西村将臣、吉澤信、横田秀夫、佐々木卓也
- Organizer
  第66回日本細胞生物学会
- Place of Presentation
  奈良県新公会堂（奈良県奈良市）
- Year and Date
  2014-06-11
- Data Source
  KAKENHI-PROJECT-26460370
[Presentation] The conformational plasticity of JRAB provides law and order in collective cell migration（集団的細胞運動においてJRABがつくりだす秩序と法則性）2014
- Author(s)
  坂根亜由子、西村将臣、横田秀夫、佐々木卓也
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-26460370
[Presentation] The conformational plasticity of JRAB provides law and order in collective cell migration（集団的細胞運動においてJRABがつくりだす秩序と法則性）2014
- Author(s)
  坂根亜由子、西村将臣、横田秀夫、佐々木卓也
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PUBLICLY-25111723
[Presentation] Efficient gene-targeting in cultured cells by CRISPR/Cas9 system using non-integrating lentiviral vector（非組込型レンチウイルスベクターを用いたCRISPR/Cas9システムによる高効率遺伝子ターゲティング）2014
- Author(s)
  松下夏樹、松下佐知、坂根亜由子、佐々木卓也、今村健志
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PUBLICLY-25111723
[Presentation] The conformational plasticity of single molecule provides law and order in collective cell migration（集団的細胞運動において１分子の構造変化がつくりだす秩序と法則）2014
- Author(s)
  坂根亜由子、西村将臣、吉澤信、横田秀夫、佐々木卓也
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-10-17
- Data Source
  KAKENHI-PUBLICLY-25111723
[Presentation] The conformational plasticity of single molecule provides law and order in collective cell migration（集団的細胞運動において１分子の構造変化がつくりだす秩序と法則）2014
- Author(s)
  坂根亜由子、西村将臣、吉澤信、横田秀夫、佐々木卓也
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-10-17
- Data Source
  KAKENHI-PROJECT-26460370
[Presentation] Efficient gene-targeting in cultured cells by CRISPR/Cas9 system using non-integrating lentiviral vector（非組込型レンチウイルスベクターを用いたCRISPR/Cas9システムによる高効率遺伝子ターゲティング）2014
- Author(s)
  松下夏樹、松下佐知、坂根亜由子、佐々木卓也、今村健志
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-26460370
[Presentation] 集団的細胞運動においてRab13-JRAB系がつくりだす秩序と法則性2014
- Author(s)
  坂根亜由子、西村将臣、吉澤信、横田秀夫、佐々木卓也
- Organizer
  第66回日本細胞生物学会
- Place of Presentation
  奈良県新公会堂（奈良県奈良市）
- Year and Date
  2014-06-11
- Data Source
  KAKENHI-PUBLICLY-25111723
[Presentation] 動く細胞2012
- Author(s)
  坂根亜由子, 佐々木卓也
- Organizer
  ViEW2012ビジョン技術の実利用ワークショップ
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2012-12-06
- Data Source
  KAKENHI-PROJECT-24790285
[Presentation] 細胞接着・運動においてRab13-JRAB系が制御する小胞輸送とアクチン細胞骨格再編成2011
- Author(s)
  坂根亜由子、佐々木卓也
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22790293
[Presentation] 細胞接着・運動においてRab13-JRAB系が制御する小胞輸送とアクチン細胞骨格再編成2011
- Author(s)
  坂根亜由子
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22790293
[Presentation] A role of JRAB in epithelial junctional development : The cross-talk between vesicular trafficking and actin cytoskeleton in the submembrane plaque細胞間接着形成過程においてJRABが制御する細胞内小胞輸送とアクチン細胞骨格系の細胞膜直下でのクロストーク機構2011
- Author(s)
  Ayuko Sakane and Takuya Sasaki
- Organizer
  第63回日本細胞生物学会大会ミニシンポジウム
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2011-06-28
- Data Source
  KAKENHI-PROJECT-22790293
[Presentation] A role of JRAB in epithelial junctional development : The cross-talk between vesicular trafficking and actin cytoskeleton in the submembrane plague2011
- Author(s)
  Ayuko Sakane
- Organizer
  第63回日本細胞生物学会大会ミニシンポジウム
- Place of Presentation
  北海道大学(北海道)(招待講演)
- Year and Date
  2011-06-28
- Data Source
  KAKENHI-PROJECT-22790293
[Presentation] The Rubicon family negatively regulates the endocytic pathway through the interactions with Rab7. RubiconファミリーはRab7との結合を介してエンドサイトーシス経路を負に制御する2010
- Author(s)
  Keisuke Tabata, Kohichi Matsunaga, Ayuko Sakane, Takuya Sasaki, Takeshi Noda and Tamotsu Yoshimori
- Organizer
  第62回日本細胞生物学会大会
- Place of Presentation
  大阪国際会議場(大阪市)
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-22790293
[Presentation] Functions of Rab family small G proteins in neurite outgrowth.神経突起形成におけるRabファミリー低分子量G蛋白質の機能2010
- Author(s)
  Takuya Sasaki and Ayuko Sakane
- Organizer
  第62回日本細胞生物学会大会シンポジウム
- Place of Presentation
  大阪国際会議場(大阪市)
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-22790293
[Presentation] 高次細胞機能発現におけるエキソサイトーシス系Rabファミリー低分子量G蛋白質の作用機構2008
- Author(s)
  佐々木卓也, 西村範行, 坂根亜由子
- Organizer
  第60回日本細胞生物学会大会
- Place of Presentation
  横浜
- Year and Date
  2008-06-30
- Data Source
  KAKENHI-PROJECT-20890149
[Presentation] Exocytotic Rab small G proteins regulate neuronal development and plasticity.2008
- Author(s)
  Takuya Sasaki, Ayuko Sakane
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20890149
[Presentation] Exocytotic Rab small G proteins regulate neuronal development and plasticity.2008
- Author(s)
  Takuya Sasaki, Ayuko Sakane
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会)
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20890149

1. 佐々木卓也 (40241278)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. 安井武史 (70314408)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. 藤方潤一 (00869159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 南川丈夫 (10637193)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 松浦善治 (50157252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 久世直也 (50852258)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 田上周路 (80420503)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. 時実悠 (80648931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. 加治佐平 (00643123)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 竹居孝二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 山田浩司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 大塚邦紘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 芳賀永

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 栗生俊彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakane Ayuko 坂根 亜由子

SAKANE Ayuko 坂根 亜由子

Research Projects

Research Products

Co-Researchers

Ultra-sensitive and rapid detection of emerging and resurging viruses based on biomedical photonics of optical frequency comb

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Role of protein conformational dynamics and disorder regions in the regulation of the actin cytoskeletonPrincipal Investigator

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Analysis for conformational change of JRAB regulating collective cell migration; from molecular information to physiological role in mousePrincipal Investigator

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Conformational plasticity of single molecule regulates actin cytoskeletal rearrangement leading to dynamics in higher structure and function of brainPrincipal Investigator

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集団的細胞運動を支える細胞内小胞輸送とアクチン細胞骨格再編成のクロストーク制御Principal Investigator

Principal Investigator

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The role of exocytosis in biological functionsPrincipal Investigator

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Synaptic formation and maturation regulated by membrane trafficking leading to higher function of the nervous systemPrincipal Investigator

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Regulation of membrane trafficking in synaptic formation and maturation.Principal Investigator

Principal Investigator

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[Book] Rab3Aと神経可塑性2010

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[Journal Article] Rapid, high-sensitivity detection of biomolecules using dual-comb biosensing2023

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[Journal Article] s-Afadin binds to MAGUIN/Cnksr2 and regulates the localization of the AMPA receptor and glutamatergic synaptic response in hippocampal neurons2023

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[Journal Article] Highly sensitive detection of nucleocapsid protein from SARS-CoV-2 using a near-infrared surface plasmon resonance sensing system2022

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[Journal Article] JRAB/MICAL-L2 undergoes liquid-liquid phase separation to form tubular recycling endosomes2021

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[Journal Article] Afadin regulates actomyosin organization through αE-catenin at adherens junctions.2020

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Sakane Ayuko 坂根亜由子

SAKANE Ayuko 坂根亜由子