Yonezawa Tomo 米沢朋

… Alternative Names

YONEZAWA, Tomo 米沢朋

YONEZAWA Tomo 米沢朋

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Researcher Number	60515964
Other IDs
Affiliation (based on the past Project Information) *help	2018 – 2022: 長崎大学, 医歯薬学総合研究科(薬学系), 准教授 2014 – 2015: 長崎大学, 医歯薬学総合研究科(薬学系), 准教授 2013: 東京理科大学, 生命医科学研究所, 助教 2011: 独立行政法人国立成育医療研究センター, システム発生・再生医学研究部, 流動研究員 2011: 独立行政法人国立成育医療研究センター, システム発生・再生医学研究部, 研究員 2009 – 2010: Tokai University, 医学部, 奨励研究員 2008: Tokai University, 医学部, 特定研究員
Review Section/Research Field	Principal Investigator Basic Section 48030:Pharmacology-related / Laboratory animal science / Medical genome science / Applied genomics Except Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
Keywords	Principal Investigator ゲノム / トランスレーショナルリサーチ / 低分子化合物 / プロテインキナーゼCε(PKCε) / 2型糖尿病 / 多発性硬化症 / 化合物ライブラリー / I型インターフェロン応答 / 新規リポーター細胞 / IL-18シグナル … More / ハイスループットスクリーニング / 独自ライブラリー / NFkB転写活性 / IRF転写活性 / IL-18 / HTS / SEAP / IRF / NFkB / 自己免疫疾患 / 炎症応答 / 新規分子 / miRNA / PKCε / 既存薬X / プロテインキナーゼC_ε / 新規治療薬 / 糖尿病 / マイクロサテライト解析 … More Except Principal Investigator TRIM / 炎症 / 感染症 / インターフェロン / SARS-CoV2-Luc / hACE２ / COVID－１９ / I型IFN応答 / SARS-Cov2-Luc / hTMPRSS2 / hACE2 / COVID-19 / 1型IFN応答 / TRIM39R Less

TRIM39Rが惹起するI型IFN応答によるCOVID-19治療法の開発
- Principal Investigator
  
  倉田里穂
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Identification of novel compounds from original chemical libraries affecting autoimmune diseases.Principal Investigator
- Principal Investigator
  
  Yonezawa Tomo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Nagasaki University
Functional analysis of novel miRNA and molecule regulating immune responses.Principal Investigator
- Principal Investigator
  
  YONEZAWA, Tomo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Nagasaki University
  Tokyo University of Science
Generation of novel drug targeting protein kinase epsilon for type 2 diabetes mellitus.Principal Investigator
- Principal Investigator
  
  YONEZAWA Tomo
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical genome science
- Research Institution
  独立行政法人国立成育医療研究センター
   Tokai University
Generation of novel small-molecule drug targeting protein kinase epsilon for type 2 diabetes mellitus.Principal Investigator
- Principal Investigator
  
  YONEZAWA Tomo
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Applied genomics
- Research Institution
  Tokai University

All 2022 2021 2020 2019 2018 2016 2015 2013 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] Nucleoside triphosphate hydrolases assay in Toxoplasm gondii and Neospora caninum for high-throughput screening using robot arm.2022
- Author(s)
  Riho Kurata, Masamitsu Harada, Jun Nagai, Xiaofeng Cui, Takayuki Isagawa, Hiroaki Semba, Yasuhiro Yoshida, Norihiko Takeda, Koji Maemura, Tomo Yonezawa.
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: in press Issue: 185
- DOI
  10.3791/62874
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06566, KAKENHI-PROJECT-22K08110
[Journal Article] Establishment of Novel Protein Interaction Assays between Sin3 and REST Using Surface Plasmon Resonance and Time-Resolved Fluorescence Energy Transfer2021
- Author(s)
  Harada, M., Nagai, J., Kurata, R., Cui, X., Isagawa, T., Semba, H., ... & Yonezawa, T.
- Journal Title
  
  International journal of molecular sciences
  
  Volume: 22(5) Issue: 5 Pages: 2323-2323
- DOI
  10.3390/ijms22052323
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02360, KAKENHI-PROJECT-18K06895, KAKENHI-PROJECT-21K06566, KAKENHI-PROJECT-19K08542
[Journal Article] Establishment of Novel High-Standard Chemiluminescent Assay for NTPase in Two Protozoans and Its High-Throughput Screening2020
- Author(s)
  Masamitsu Harada, Jun Nagai, Riho Kurata, Kenji Shimizu, Xiaofeng Cui, Takayuki Isagawa, Hiroaki Semba, Jun Ishihara, Yasuhiro Yoshida, Norihiko Takeda, Koji Maemura, Tomo Yonezawa
- Journal Title
  
  Marine Drugs
  
  Volume: 18 Issue: 3 Pages: 161-161
- DOI
  10.3390/md18030161
- NAID
  120006988256
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06895, KAKENHI-PROJECT-17K09592, KAKENHI-PROJECT-16K21229, KAKENHI-PROJECT-18H02360
[Journal Article] Novel Reporter System Monitoring IL-18 Specific Signaling Can Be Applied to High-Throughput Screening2020
- Author(s)
  Kurata R, Shimizu K, Cui X, Harada M, Isagawa T, Semba H, Ishihara J, Yamada K, Nagai J, Yoshida Y, Takeda N, Maemura K, Yonezawa T.
- Journal Title
  
  Marine Drugs
  
  Volume: 18 Issue: 1 Pages: 60-60
- DOI
  10.3390/md18010060
- NAID
  120006988310
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06895, KAKENHI-PROJECT-17K09592, KAKENHI-PROJECT-16K21229, KAKENHI-PROJECT-18H02360, KAKENHI-PROJECT-18K06718
[Journal Article] Establishment of novel cells stably secreting various human IL-18 recombinant proteins.2019
- Author(s)
  Asuka Kumagai, Kenji Shimizu, Riho Kurata, Xiaofeng Cui, Takayuki Isagawa, Msamitsu Harada, Jun Nagai, Yasuhiro Yoshida, Kei-ichi Ozaki, Norihiko Takeda, Hiroaki Semba and Tomo Yonezawa
- Journal Title
  
  Current Pharmaceutical Biotechnology
  
  Volume: 20 Issue: 1 Pages: 47-55
- DOI
  10.2174/1389201020666190206203640
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06895, KAKENHI-PROJECT-16K21229, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-18K06694, KAKENHI-PROJECT-18H02360
[Journal Article] TNF-α induces caspase-1 activation independently of simultaneously induced NLRP3 in 3T3-L1 cells.2016
- Author(s)
  Furuoka M, Ozaki K, Sadatomi D, Mamiya S, Yonezawa T, Tanimura S, Takeda K.
- Journal Title
  
  J. Cell Physiol.
  
  Volume: in press Issue: 12 Pages: 1-7
- DOI
  10.1002/jcp.25385
- NAID
  120006987671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460067, KAKENHI-PROJECT-25830062, KAKENHI-PROJECT-26293016
[Journal Article] Supplementation of long-chain fatty acids with lactating mammary glands and beef cow has potential benefits.2015
- Author(s)
  Riho Kurata, Xiaofeng Cui, Roh Sang-gun, Tomo Yonezawa
- Journal Title
  
  Advances in plants and agriculture research
  
  Volume: 2 Issue: 5 Pages: 00063-00063
- DOI
  10.15406/apar.2015.02.00063
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25830062
[Journal Article] Free fatty acids-sensing G protein-coupled receptors in drug targeting and therapeutics2013
- Author(s)
  Tomo Yonezawa, Riho Kurata, Kaori Yoshida, Masanori A Murayama, Xiaofeng Cui and Akihiko Hasegawa
- Journal Title
  
  Current Medicinal Chemistry
  
  Volume: 20 Issue: 31 Pages: 3855-3871
- DOI
  10.2174/09298673113209990168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J07231, KAKENHI-PROJECT-25830062
[Journal Article] MicroRNA-125b regulates the expression of aggrecanase-1 (ADAMTS-4) in human osteoarthritic chondrocytes.2013
- Author(s)
  Matsukawa T, Sakai T, Yonezawa T, Hiraiwa H, Hamada T, Nakashima M, Ono Y, Ishizuka S, Nakahara H, Lotz MK, Asahara H, Ishiguro N.
- Journal Title
  
  Arthritis Res Ther.
  
  Volume: 15(1) Issue: 1
- DOI
  10.1186/ar4164
- NAID
  40020134052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659672, KAKENHI-PROJECT-25830062
[Journal Article] TRIM39, but not TRIM39B, regulates type I interferon response.2013
- Author(s)
  Riho Kurata, Atsushi Tajima, Tomo Yonezawa and Hidetoshi Inoko
- Journal Title
  
  Biochemcal and Biophysical Research Communications
  
  Volume: 436 Issue: 1 Pages: 90-95
- DOI
  10.1016/j.bbrc.2013.05.064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J07231, KAKENHI-PROJECT-25290036, KAKENHI-PROJECT-25830062
[Journal Article] PKC delta and epsilon in drug targeting and therapeutics.2009
- Author(s)
  I.Tomo Yonezawa, Riho Kurata, Minoru Kimura, Hidetoshi Inoko
- Journal Title
  
  Recent Patents on DNA and Gene Sequences 3
  
  Pages: 96-101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20810031
[Journal Article] Hidetoshi Inoko PKC delta and epsilon in drug targeting and therapeutics.2009
- Author(s)
  Tomo Yonezawa, Riho Kurata, Minoru Kimura
- Journal Title
  
  Recent Patents on DNA and Gene Sequences 3
  
  Pages: 96-101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20810031
[Presentation] Establishment of novel protein interaction assays between Sin3b and REST Using surface plasmon resonance and time-resolved 4 fluorescence energy transfer.2021
- Author(s)
  M. Harada, R. Kurata, Y. Yoshida, T. Yonezawa
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06566
[Presentation] 原虫感染症における生体内を検出するアッセイ系の樹立2020
- Author(s)
  米沢　朋
- Organizer
  第43回日本分子生物学会年会、ワークショップ（環境因子と生体防御機構をイメージする！）
- Invited
- Data Source
  KAKENHI-PROJECT-18K06895
[Presentation] Establishment of novel reporter cells stably maintaining transcription factor-driven human secreted alkaline phosphatase expression.2018
- Author(s)
  Asuka Kumagai, Riho Kurata, Xiaofeng Cui, Masamitsu Harada, Jun Nagai, Yasuhiro Yoshida, Kei-ichi Ozaki and Tomo Yonezawa
- Organizer
  ASCB/EMBO meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06895
[Presentation] Establishment of novel cells stably secreting various human IL18 recombinant proteins.2018
- Author(s)
  Asuka Kumagai, Kenji Shimizu, Riho Kurata, Xiaofeng Cui, Takayuki Isagawa, Masamitsu Harada, Jun Nagai,Yasuhiro Yoshida, Kei-ichi Ozaki and Tomo Yonezawa
- Organizer
  ASCB/EMBO meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06895
[Presentation] TRIM39, but not TRIM39B, regulates type I interferon response.2013
- Author(s)
  Riho Kurata, Atsushi Tajima, Tomo Yonezawa, Hidetoshi Inok
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-25830062
[Presentation] TRIM39R, but not TRIM39B regulates type I interferon2013
- Author(s)
  倉田　里穗、田嶋　敦、米沢　朋、猪子　英俊
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25830062
[Presentation] Transcriptomic analysis of miRNA in differentiation of T cell subsets2013
- Author(s)
  Tomo Yonezawa
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25830062
[Presentation] Functional analysis for microRNA involving in arthritis.2013
- Author(s)
  Tomo Yonezawa
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-25830062
[Presentation] Combination with alpha sphere filter method and surface Plasmon reso nance-based assay identified small molecule mimicking V1-2.2010
- Author(s)
  Tomo Yonezawa
- Organizer
  BMB2010
- Place of Presentation
  神戸(ポートピアホール)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22710194
[Presentation] PKCεを標的とした2型糖尿病に対する新規低分子化合物による治療薬の開発2008
- Author(s)
  米沢朋
- Organizer
  東海大学総合医学研究所第4回研究会
- Place of Presentation
  湯河原
- Data Source
  KAKENHI-PROJECT-20810031
[Presentation] PKCεを標的とした2型糖尿病に対する新規低分子化合物による治療薬の開発2008
- Author(s)
  米沢朋
- Organizer
  東海大学総合医学研究所、第4回研究会
- Place of Presentation
  湯河原
- Year and Date
  2008-10-03
- Data Source
  KAKENHI-PROJECT-20810031
[Presentation] Pronuclear injection of circular plasmids expressing hCas9 and gRNA generates mutant mice in genes involved in immune responses.
- Author(s)
  Tomo Yonezawa, Akihisa Oda, Riho Kurata, Sachiko Kubo, Shyuhei Ogawa, Yoichiro Iwakura
- Organizer
  The 43rd Annual Meeting of The Japanese Society for Immunology.
- Place of Presentation
  京都国際会議場（京都府）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25830062
[Presentation] Pronuclear injection of circular plasmids expressing hCas9 and gRNA generates mutant mice in genes involved in immune responses.
- Author(s)
  Tomo Yonezawa, Akihisa Oda, Riho Kurata, Sachiko Kubo, Shyuhei Ogawa, Yoichiro Iwakura
- Organizer
  International Cytokine & Interferon Society (ICIS)-Cytokines Down Under in 2014: From Bench to Beyond
- Place of Presentation
  Melbourne, Australia
- Year and Date
  2014-10-26 – 2014-10-29
- Data Source
  KAKENHI-PROJECT-25830062

1. 倉田里穂 (70711729)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. HIRAIWA Hideki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. HAMADA Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 武田弘資

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 谷村進

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 酒井忠博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 仙波宏章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yonezawa Tomo 米沢 朋

YONEZAWA, Tomo 米沢 朋

YONEZAWA Tomo 米沢 朋

Research Projects

Research Products

Co-Researchers

TRIM39Rが惹起するI型IFN応答によるCOVID-19治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of novel compounds from original chemical libraries affecting autoimmune diseases.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of novel miRNA and molecule regulating immune responses.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Generation of novel drug targeting protein kinase epsilon for type 2 diabetes mellitus.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Generation of novel small-molecule drug targeting protein kinase epsilon for type 2 diabetes mellitus.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Nucleoside triphosphate hydrolases assay in Toxoplasm gondii and Neospora caninum for high-throughput screening using robot arm.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of Novel Protein Interaction Assays between Sin3 and REST Using Surface Plasmon Resonance and Time-Resolved Fluorescence Energy Transfer2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of Novel High-Standard Chemiluminescent Assay for NTPase in Two Protozoans and Its High-Throughput Screening2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Novel Reporter System Monitoring IL-18 Specific Signaling Can Be Applied to High-Throughput Screening2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Establishment of novel cells stably secreting various human IL-18 recombinant proteins.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TNF-α induces caspase-1 activation independently of simultaneously induced NLRP3 in 3T3-L1 cells.2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Supplementation of long-chain fatty acids with lactating mammary glands and beef cow has potential benefits.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Free fatty acids-sensing G protein-coupled receptors in drug targeting and therapeutics2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MicroRNA-125b regulates the expression of aggrecanase-1 (ADAMTS-4) in human osteoarthritic chondrocytes.2013

Yonezawa Tomo 米沢朋

YONEZAWA, Tomo 米沢朋

YONEZAWA Tomo 米沢朋