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Ebana Yusuke  江花 有亮

… Alternative Names

EBANA Yusuke  江花 有亮

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Researcher Number 60517043
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-5162-0838
Affiliation (Current) 2025: 東京科学大学, 大学院医歯学総合研究科, 講師
Affiliation (based on the past Project Information) *help 2024: 東京医科歯科大学, 統合研究機構, 講師
2017 – 2021: 東京医科歯科大学, 統合研究機構, 講師
2015 – 2016: 東京医科歯科大学, 学内共同利用施設等, 講師
2014: 東京医科歯科大学, 難治疾患研究所, 助教
2010 – 2012: Tokyo Medical and Dental University, 難治疾患研究所, 助教
2009: Tokyo Medical and Dental University, 難治疾患研究所, 教員
Review Section/Research Field
Principal Investigator
Circulatory organs internal medicine / Basic Section 53020:Cardiology-related / Medical genome science
Except Principal Investigator
Cardiovascular medicine
Keywords
Principal Investigator
心房細動 / ゲノムワイド関連研究 / 個別化医療 / ゲノムワイド研究 / 性差 / 多遺伝子リスクスコア / 危険因子 / 心筋細胞 / 機能解析 / タンパク質品質管理 … More / NEURL / mTOR / mTOR / ENOX1 / 肺静脈隔離術 / cis制御エレメント / cis制御 / ゲノムワイド / 分子心臓病態学 / 全ゲノム解析 / GWAS / SNP … More
Except Principal Investigator
サイトカイン / 転写因子 / 遺伝子多型 / インフラマソーム / 一塩基多型 / 高安動脈炎 Less
  • Research Projects

    (5 results)
  • Research Products

    (22 results)
  • Co-Researchers

    (8 People)
  •  Research for risk factors and sex differences of atrial fibrillation onset using genetic methods.Principal Investigator

    • Principal Investigator
      江花 有亮
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Quality control of protein in cardiomyochyte by atrial fibrillation associated gene, NEURL1Principal Investigator

    • Principal Investigator
      Ebana Yusuke
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical genome science
    • Research Institution
      Tokyo Medical and Dental University
  •  Exploration of the genes which are responsible for the pathogenesis of Takayasu arteritis

    • Principal Investigator
      ISOBE MITSUAKI
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Functional analysis and clinical study of atrial fibrillation-associated genesPrincipal Investigator

    • Principal Investigator
      EBANA Yusuke
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Identification and functional analysis of atrial fibrillation -associated loci through genomewide association studyPrincipal Investigator

    • Principal Investigator
      EBANA Yusuke
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Tokyo Medical and Dental University

All 2020 2019 2018 2017 2016 2013 2012 Other

All Journal Article Presentation

  • [Journal Article] Functional Role of the L396R Mutation of Tks5 Identified by an Exome-Wide Association Study in Atrial Fibrillation2020

    • Author(s)
      Yang Xiaoxi、Sasano Tetsuo、Ebana Yusuke、Takeuchi Jun K.、Ihara Kensuke、Yamazoe Masahiro、Furukawa Tetsushi
    • Journal Title

      Circ J

      Volume: 84 Issue: 12 Pages: 2148-2157

    • DOI

      10.1253/circj.CJ-20-0101

    • NAID

      130007942473

    • ISSN
      1346-9843, 1347-4820
    • Year and Date
      2020-11-25
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07251, KAKENHI-PROJECT-19K08536, KAKENHI-PROJECT-20K21598, KAKENHI-PROJECT-19KK0218, KAKENHI-PROJECT-18H02803, KAKENHI-PROJECT-16H06279
  • [Journal Article] Mutant KCNJ3 and KCNJ5 potassium channels as novel molecular targets in bradyarrhythmias and atrial fibrillation.2019

    • Author(s)
      Yamada N, Asano Y, Fujita M, Yamazaki S, Inanobe A, Matsuura N, Kobayashi H, Ohno S, Ebana Y, Tsukamoto O, Ishino S, Takuwa A, Kioka H, Yamashita T, Hashimoto N, Zankov DP, Shimizu A, Asakura M, Asanuma H, Kato H, Nishida Y, Miyashita Y, Shinomiya H, Naiki N, Hayashi K, Makiyama T, Ogita H, et al.
    • Journal Title

      Circulation

      Volume: In press Issue: 18 Pages: 2157-2169

    • DOI

      10.1161/circulationaha.118.036761

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08627, KAKENHI-PROJECT-17K08657, KAKENHI-PROJECT-17K09577, KAKENHI-PROJECT-17K09578, KAKENHI-PROJECT-18K07875, KAKENHI-PROJECT-18K08100, KAKENHI-PROJECT-17F17418, KAKENHI-PROJECT-15K09111, KAKENHI-PROJECT-15KK0302, KAKENHI-PROJECT-17K07251, KAKENHI-PROJECT-18K08033, KAKENHI-PROJECT-19K08538, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17H01560, KAKENHI-PROJECT-17K09495, KAKENHI-PROJECT-17H04018, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18H04074, KAKENHI-PROJECT-18H02803, KAKENHI-PROJECT-18H02808, KAKENHI-PROJECT-18K19547, KAKENHI-PROJECT-19H03652
  • [Journal Article] Pathway analysis with genome-wide association study (GWAS) data detected the association of atrial fibrillation with the mTOR signaling pathway2019

    • Author(s)
      Ebana Yusuke、Sun Yihan、Yang Xiaoxi、Watanabe Taiju、Makita Satoru、Ozaki Kouichi、Tanaka Toshihiro、Arai Hirokuni、Furukawa Tetsushi
    • Journal Title

      IJC Heart & Vasculature

      Volume: 24 Pages: 100383-100383

    • DOI

      10.1016/j.ijcha.2019.100383

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07251, KAKENHI-PROJECT-18H05285, KAKENHI-PROJECT-18H02803
  • [Journal Article] Networking analysis on superior vena cava arrhythmogenicity in atrial fibrillation2019

    • Author(s)
      Ebana Yusuke、Furukawa Tetsushi
    • Journal Title

      IJC Heart & Vasculature

      Volume: 22 Pages: 150-153

    • DOI

      10.1016/j.ijcha.2019.01.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07251, KAKENHI-PROJECT-18H02803
  • [Journal Article] Association of the Clinical and Genetic Factors With Superior Vena Cava Arrhythmogenicity in Atrial Fibrillation2018

    • Author(s)
      Ebana Y, Nitta J, Takahashi Y, Miyazaki S, Suzuki M, Liu L, Hirao K, Kanda E, Isobe M, Furukawa T
    • Journal Title

      Circ J

      Volume: 82 Issue: 1 Pages: 71-77

    • DOI

      10.1253/circj.CJ-17-0350

    • NAID

      130006281956

    • ISSN
      1346-9843, 1347-4820
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26293052, KAKENHI-PROJECT-17K07251
  • [Journal Article] Endoscopic features and genetic background of inflammatory bowel disease complicated with Takayasu arteritis.2017

    • Author(s)
      Akiyama S, Fujii T, Matsuoka K, Yusuke E, Negi M, Takenaka K, Nagahori M, Ohtsuka K, Isobe M, Watanabe M.
    • Journal Title

      J Gastroenterol Hepatol.

      Volume: 32 Issue: 5 Pages: 1011-1017

    • DOI

      10.1111/jgh.13640

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460963, KAKENHI-PROJECT-26670399, KAKENHI-PROJECT-17K09370, KAKENHI-PROJECT-17K09372, KAKENHI-PROJECT-17K07251
  • [Journal Article] Effects of immunosuppressive and biological agents on refractory Takayasu arteritis patients unresponsive to glucocorticoid treatment.2017

    • Author(s)
      Ohigashi H, Tamura N, Ebana Y, Harigai M, Maejima Y, Ashikaga T, Isobe M.
    • Journal Title

      J Cardiol

      Volume: 69 Issue: 5 Pages: 774-778

    • DOI

      10.1016/j.jjcc.2016.07.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670399, KAKENHI-PROJECT-17K07251
  • [Journal Article] Clinical utility and functional analysis of variants in atrial fibrillation-associated locus 4q25.2017

    • Author(s)
      Ebana Y, Ozaki K, Liu L, Hachiya H, Hirao K, Isobe M, Kubo M, Tanaka T, Furukawa T.
    • Journal Title

      Journal of Cardiology

      Volume: - Issue: 4 Pages: 366-373

    • DOI

      10.1016/j.jjcc.2016.11.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H04726, KAKENHI-PROJECT-26293052, KAKENHI-PROJECT-17K07251
  • [Journal Article] Genetic variants associated with susceptibility to atrial fibrillation in Japanese population2017

    • Author(s)
      Liu L, Ebana Y, Nitta J, Takahashi Y, Miyazaki S, Tanaka T, Komura M, Isobe M, Furukawa T
    • Journal Title

      Can. J. Cardiol.

      Volume: 33 Pages: 443-449

    • DOI

      10.1016/j.ijcard.2017.06.046

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293052, KAKENHI-PROJECT-17K07251
  • [Journal Article] Identification of six novel genetic loci associated with atrial fibrillation in Japanese population.2017

    • Author(s)
      Low SK, Takahashi A, Ebana Y, Ozaki K, Christophersen IE, Ellinor PT, AFGen Consortium, Ogishima S, Yamamoto M, Satoh M, Sasaki M, Yamaji T, Iwasaki M, Tsugane S, Tanaka K, Naito M, Wakai K, Tanaka H, Furukawa T, Kubo M, Ito K, Kamatani Y, Tanaka T.
    • Journal Title

      Nature Genetics

      Volume: - Issue: 6 Pages: 953-958

    • DOI

      10.1038/ng.3842

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04726, KAKENHI-PROJECT-15K08539, KAKENHI-PROJECT-16K00385, KAKENHI-PROJECT-26293052, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17K07251
  • [Journal Article] Genetic variants associated with susceptibility to atrial fibrillation in Japanese population2016

    • Author(s)
      Liu L, Ebana Y, Nitta JI, Takahashi Y, Miyazaki S, Tanaka T, Komura M, Isobe M, Furukawa T
    • Journal Title

      Canadean Journal of Cardiology

      Volume: 33 Issue: 4 Pages: 443-449

    • DOI

      10.1016/j.cjca.2016.10.029

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15049, KAKENHI-PROJECT-26293052, KAKENHI-PROJECT-17K07251
  • [Presentation] Genetics of atrial fibrillation in Japanese Population2018

    • Author(s)
      Yusuke Ebana
    • Organizer
      The 11th Asia Pacific Heart Rhythm Society Scientific Session
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07251
  • [Presentation] A SNP in 4p15.2 was Identified as a Novel Atrial Fibrillation Associated Locus Through the GWAS in Japanese Population2013

    • Author(s)
      Yusuke Ebana
    • Organizer
      第77回日本循環器学会学術集会
    • Place of Presentation
      横浜、パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23790841
  • [Presentation] During the transdifferentiation from mesenchyme to cardiomyocyte, atrial fibrillation associated locus 4q25 enhanced PITX2c expression to interact with its promoter2013

    • Author(s)
      Yusuke Ebana, Kouich Ozaki, Toshihiro Tanaka, Mitsuaki Isobe, TetsushiFurukawa
    • Organizer
      第77回日本循環器学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23790841
  • [Presentation] During the transdifferentiation from mesenchyme to cardiomyocyte, atrial fibrillation associated locus 4q25 enhanced PITX2c expression to interact with its promoter2013

    • Author(s)
      Yusuke Ebana
    • Organizer
      第77回日本循環器学会学術集会
    • Place of Presentation
      横浜、パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23790841
  • [Presentation] A SNP in 4p15.2 was Identified as a Novel Atrial Fibrillation Associated Locus Through the GWAS in Japanese Population2013

    • Author(s)
      Yusuke Ebana, Hitoshi Hachiya, Kenzo Hirao, Mitsuaki Isobe, Osamu Inaba, Junichi Nitta, Motoji Sawabe, Atsushi Takahashi, Hiroaki Nakamura Tetsushi Furukawa
    • Organizer
      第77回日本循環器学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23790841
  • [Presentation] A variant in locus of Caveolin-1 confers atrial fibrillation and left atrial enlargement2012

    • Author(s)
      江花有亮
    • Organizer
      日本人類遺伝学会第57回大会
    • Place of Presentation
      東京、京王プラザホテル
    • Data Source
      KAKENHI-PROJECT-23790841
  • [Presentation] 心房細動関連遺伝子座4q25の遺伝子多型によるPITX2遺伝子発現の制御2012

    • Author(s)
      江花有亮、磯部光章、古川哲史
    • Organizer
      第29回日本心電学会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-23790841
  • [Presentation] Caveolin1遺伝子座の遺伝子多型と心房細動発症および左房拡大に関する解析2012

    • Author(s)
      江花有亮、牧田哲、荒井裕国、磯部光章、古川哲史
    • Organizer
      第57回日本人類遺伝学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23790841
  • [Presentation] Polymorphisms on Atrial Fibrillation Associated Locus 4q25 Could Accelerate the Disease Onset and the Recurrence After Pulmonary Vein Isolation

    • Author(s)
      江花有亮
    • Organizer
      第76回日本循環器学会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23790841
  • [Presentation] Atrial fibrillation-associated locus 4q25 has the cis-regulatory function toward the neighboring PITX2 genes

    • Author(s)
      江花有亮
    • Organizer
      第76回日本循環器学会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23790841
  • [Presentation] A variant in locus of Caveolin-1 confers atrial fibrillation and left atrial enlargement

    • Author(s)
      江花有亮
    • Organizer
      第76回日本循環器学会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23790841
  • 1.  ISOBE MITSUAKI (80176263)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  前嶋 康浩 (40401393)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  OZAKI Kouichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 4.  渡辺 守
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  藤井 俊光
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  扇田 久和
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  古川 哲史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 8.  伊藤 薫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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