Oshima Koichi 大嶋宏一

… Alternative Names

OSHIMA Koichi 大嶋宏一

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Researcher Number	60525377
Other IDs
Affiliation (Current)	2025: 埼玉県立小児医療センター (臨床研究部), 血液腫瘍科, 医長
Affiliation (based on the past Project Information) *help	2019 – 2022: 埼玉県立小児医療センター (臨床研究部), 血液腫瘍科, 医長 2013: 京都大学, ips細胞研究所, 研究員 2010 – 2013: 京都大学, iPS細胞研究所, 特定研究員 2012: 京都大学, iPS 細胞研究所, 特定研究員 2012: 京都大学, iPS細胞研究所, 研究員 … More 2012: 京都大学, 学内共同利用施設等, 研究員 2011: 京都大学, ｉＰＳ細胞研究所, 特定研究員 2011: 京都大学, ｉＰＳ細胞研究所, 研究員 2010: 京都大学, iPS細胞研究センター, 特定研究員 2010: Kyoto University, ips細胞研究所, 特定研究員 2009: Kyoto University, 物質-細胞統合システム拠点, 特定研究員 Less
Review Section/Research Field	Principal Investigator Pediatrics / 0901:Oncology and related fields Except Principal Investigator Pediatrics / Biological Sciences
Keywords	Principal Investigator ATR阻害剤 / スクリーニング / CRISPR / 神経芽腫 / Adenylate kinase 2 / Adenylate kinase2 / 細網異形成症 / マススクリーニング / 重症複合免疫不全症 Except Principal Investigator iPS細胞 … More / 感染症 / 発生・分化 / 移植・再生医療 / 遺伝子 / 免疫学 / ニッチ / ストロマ細胞 / 造血幹細胞 / ES細胞 / ナイーブT細胞 / 骨髄異形成症候群 / GATA2 / NK細胞分化 / B細胞分化 / 樹状細胞分化 / 原発性免疫不全症 / 小児免疫・アレルギー・膠原病学 / 創薬 / 疾患特異的 / NOGマウス / 疾患解析 / 遺伝子改変 / 遺伝性疾患 Less

Genome-wide CRISPR/Cas9 screening for drug target discovery in neuroblastomaPrincipal Investigator
- Principal Investigator
  
  Oshima Koichi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0901:Oncology and related fields
- Research Institution
  Saitama Children's Medical Center
Hematopoietic stem cell potential is propagated by human pluripotent stem cell-derived endothelial stroma
- Principal Investigator
  
  NAKAHATA Tatsutoshi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto University
Analysis of pathophysiology and identification of the causative gene(s) of primary immunodeficiency with B, NK, dendritic cell deficiency
- Principal Investigator
  
  IMAI KOHSUKE
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Tokyo Medical and Dental University
疾患特異的iPS細胞を用いた細網異形成症の病態解析Principal Investigator
- Principal Investigator
  
  大嶋宏一
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto University
自己識別機構の破綻をきたす免疫不全症の病態解明と原因遺伝子同定
- Principal Investigator
  
  野々山恵章
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Defense Medical College
Recapitulation of phenotypes and discovery of a novel treatment with disease-specific human ES/ iPS cells from various hereditary diseases
- Principal Investigator
  
  NAKAHATA Tatsutoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto University
Research for developing of a screening method for the congenital immunodeficiency by KREC/TREC to apply the method to the pathologic analysis
- Principal Investigator
  
  NONOYAMA Shigeaki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  National Defense Medical College
Development of easy and cost-effective mass-screening of severe combined immunodeficiency using neonatal guthrie cards.Principal Investigator
- Principal Investigator
  
  OSHIMA Koichi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto University

All 2022 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] The role of CRISPR screening in leukemia research2022
- Author(s)
  大嶋宏一
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 63 Issue: 11 Pages: 1580-1585
- DOI
  10.11406/rinketsu.63.1580
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K23928
[Journal Article] Robust and highly-efficient differentiation of functional monocytic cells from human pluripotent stem cells under serum- and feeder cell- free conditions.2013
- Author(s)
  Yanagimachi MD, Niwa A, Tanaka T, Ozaki F, Nishimoto S, Murata Y, Yasumi T, Ito J, Tomida S, Oshima K, Asaka I, Goto H, Heike T, Nakahata T, Saito MK
- Journal Title
  
  PLoS ONE
  
  Volume: 8(4) Issue: 4 Pages: e59243-e59243
- DOI
  10.1371/journal.pone.0059243
- NAID
  120005244458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249042, KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-22591159, KAKENHI-PROJECT-23657147, KAKENHI-PROJECT-24659496, KAKENHI-PROJECT-24790997, KAKENHI-PROJECT-25461591
[Journal Article] Kasabach-Merritt Phenomenon: A Report of 11 Cases From a Single Institution.2013
- Author(s)
  Yasui N, Koh K, Kato M, Park MJ, Tomizawa D, Oshima K, Uchisaka N, Gocho Y, Arakawa A, Seki M, Oguma E, Kishimoto H, Watanabe S, Kikuchi A, Hanada R.
- Journal Title
  
  J Pediatr Hematol Oncol.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] GATA-2 anomaly and clinical phenotype of a sporadic case of lymphedema, dendritic cell, monocyte, B- and NK-cell (DCML) deficiency, and myelodysplasia2012
- Author(s)
  Ishida H, Imai K, Homma K, Tamura S, Imamura T, Itoh M, Nonoyama S
- Journal Title
  
  Eur J Pediatr
  
  Volume: 171 Issue: 8 Pages: 1273-1276
- DOI
  10.1007/s00431-012-1715-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-23591547, KAKENHI-PROJECT-23591561
[Journal Article] Matched sibling donor stem cell transplantation for Fanconi anemia patients with T-cell somatic mosaicism2012
- Author(s)
  Yabe M, Shimizu T, Morimoto T, Koike T, Takakura H, Tsukamoto H, Muroi K, Oshima K, Asami K, Takata M, Yamashita T, Kato S, Yabe H
- Journal Title
  
  Pediatric Transplant
  
  Volume: (印刷中) Issue: 4 Pages: 340-345
- DOI
  10.1111/j.1399-3046.2012.01669.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591262, KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-23501257, KAKENHI-PROJECT-23651046, KAKENHI-PROJECT-24310042, KAKENHI-PLANNED-23114010, KAKENHI-PUBLICLY-23131503
[Journal Article] A dual reporter splicing assay using HaloTag-containing proteins. Curr Chem Genomics.2012
- Author(s)
  Oshima K, Nagase T, Imai K, Nonoyama S, Obara M, Mizukami T, Nunoi H, Kanegane H, Kuribayashi F, Amemiya S, Ohara O.
- Journal Title
  
  Curr Chem Genomics.
  
  Volume: 6 Issue: 1 Pages: 27-37
- DOI
  10.2174/1875397301206010027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-23591561, KAKENHI-PROJECT-24591563
[Journal Article] Clinical profile and genetic basis of Wiskott-Aldrich syndrome at Chandigarh, North India.2012
- Author(s)
  Suri D, Singh S, Rawat A, Gupta A, Kamae C, Honma K, Nakagawa N, Imai K, Nonoyama S, Oshima K, Mitsuiki N, Ohara O, Bilhou-Nabera C,
- Journal Title
  
  Asian Pac J Allergy Immunol
  
  Volume: 30 Pages: 71-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591561
[Journal Article] Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery2012
- Author(s)
  Tanaka T., Takahashi K., Yamane M., Tomida S., Nakamura S., Oshima K., Niwa A., Nishikomori R., Kambe N., Hara H., Mitsuyama M., Morone N., Heuse J.E., Yamamoto T., Watanabe A., Sato-Otsubo A., Ozawa S., Asaka I., Heike T., Yamanaka S., Nak
- Journal Title
  
  Blood
  
  Volume: 120(6) Issue: 6 Pages: 1299-308
- DOI
  10.1182/blood-2012-03-417881
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249042, KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-22790283, KAKENHI-PROJECT-23310087, KAKENHI-PROJECT-23390280, KAKENHI-PROJECT-23657147, KAKENHI-PROJECT-24390263, KAKENHI-PROJECT-24590524, KAKENHI-PROJECT-24659496
[Journal Article] Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery.2012
- Author(s)
  Tanaka T., Oshima K., Niwa A., Nishikomori R., Kambe N., Hara H., Mitsuyama M., Ozawa S., Asaka I., Heike T., Yamanaka S., Nakahata T., Saito M.K. 他７名１５番目
- Journal Title
  
  Blood
  
  Volume: 120 Pages: 1299-1308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659496
[Journal Article] Clinical profile and genetic basis of Wiskott-Aldrich syndrome at Chandigarh, North India2012
- Author(s)
  Suri D, Singh S, Rawat A, Gupta A, Kamae C, Honma K, Nakagawa N, Imai K, Nonoyama S, Oshima K, Mitsuiki N, Ohara O, Bilhou-Nabera C.
- Journal Title
  
  Asian Pac J Allergy Immunol
  
  Volume: 30 Pages: 71-8
- Data Source
  KAKENHI-PROJECT-23591561
[Journal Article] Clinical profile and genetic basis of Wiskott-Aldrich syndrome at Chandigarh, north India2012
- Author(s)
  Suri D, Singh S, Rawat A, Gupta A, Kamae C, Honma K, Nakagawa N, Imai K, Nonoyama S, Oshima K, Mitsuiki N, Ohara O, Bilhou-Nabera C, Proust A, Ahluwalia J, Dogra S, Saikia B, Walker Minz R, Sehgal S
- Journal Title
  
  Asian Pac J Allergy Immunol
  
  Volume: 30 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] A Dual Reporter Splicing Assay Using HaloTag-containing Proteins2012
- Author(s)
  Oshima K, Nagase T, Imai K, Nonoyama S, Obara M, Mizukami T, Nunoi H, Kanegane H, Kuribayashi F, Amemiya S, Ohara O.
- Journal Title
  
  Curr Chem Genomics
  
  Volume: 6 Pages: 27-37
- Data Source
  KAKENHI-PROJECT-23591561
[Journal Article] Clinical profile and genetic basis of Wiskott-Aldrich syndrome at Chandigarh, north India2012
- Author(s)
  Suri D, Singh S, Rawat A, Gupta A, Kamae C, Honma K, Nakagawa N, Imai K, Nonoyama S, Oshima K, Mitsuiki N, Ohara O, Bilhou-Nabera C, Proust A, Ahluwalia J, Dogra S, Saikia B, Walker Minz R, Sehgal S
- Journal Title
  
  Asian Pac J Allergy Immunol
  
  Volume: 30 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Quantification of s-deleting recombination excision circles in Guthrie cards for the identification of early B-cell maturation defects.2011
- Author(s)
  Nakaeawa N, Imai K, Kanegane H, Sate H, Yamada M, Kondoh K, Okada S, Kobayashi M, Agematsu K, Takada H, Mitsuiki N, Oshima K, Ohara O, Suri D, Rawat A, Singh S, Pan-Hammarstrom Q, Hammarstrom L, Reichenbach J, Seger R, Ariga T, Hara T, Miyawaki T, Nonovama_S.
- Journal Title
  
  J Allergy Clin Immunol. Epub ahead of print.
- Data Source
  KAKENHI-PROJECT-21791018
[Journal Article] Rapid diagnosis of familial hemophagocytic lymphohistiocytosis type 3 (FHL3) by flow cytometric detection of intraplatelet Munc 13-4 protein.2011
- Author(s)
  Murata Y., Yasumi T., Shirakawa R., Izawa K., Sakai H., Abe J., Tanaka N., Kawai T., Oshima K., Saito M., Nishikomori R., Ohara O.、Ishii E., Nakahata T., Horiuchi H., Heike T.
- Journal Title
  
  Blood
  
  Volume: 118 Issue: 5 Pages: 1225-1230
- DOI
  10.1182/blood-2011-01-329540
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249042, KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-22501009, KAKENHI-PROJECT-22591159, KAKENHI-PUBLICLY-23113702, KAKENHI-PUBLICLY-23121503
[Journal Article] A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors2011
- Author(s)
  Niwa A, Heike T, Umeda K, Oshima K, Kato I, Sakai H, Suemori H, Nakahata T, Saito MK.Jul
- Journal Title
  
  PLoS One
  
  Volume: 6
- NAID
  120003324603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Novel mutations of MVK gene in Japanese family members affected with hyperimmunoglobulinemia D and periodic fever syndrome2011
- Author(s)
  Mizuno T, Sakai H, Nishikomori R, Oshima K, Ohara O, Hata I, Shigematsu Y, Ishige T, Tamura K, Arakawa H
- Journal Title
  
  Rheumatol Interest
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Novel mutations of MVK gene in Japanese family members affected with hyperimmunoglobulinemia D and periodic fever syndrome2011
- Author(s)
  Mizuno T, Sakai H, Nishikomori R, Oshima K, Ohara O, Hata I, Shigematsu Y, Ishige T, Tamura K, Arakawa H
- Journal Title
  
  Rheumatol Interest
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors2011
- Author(s)
  Niwa A, Heike T, Umeda K, Oshima K, Kato I, Sakai H, Suemori H, Nakahata T, Saito MK.Jul
- Journal Title
  
  PLoS One
  
  Volume: 6
- NAID
  120003324603
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Quantification ofκ-deleting recombination excision circles in Guthrie cards for the identification of early B-cell maturation defects2011
- Author(s)
  Nakagawa N, Imai K,Kanegane H, Sato H,Yamada M, Kondoh K,Okada S, Kobayashi M, Agematsu K,Takada H, Mitsuiki N, Oshima K, Ohara O, Suri D, Rawat A, Singh S, Pan-Hammarström Q, Hammarstrom L, Reichenbach J, Seger R, Ariga T, Hara T, Miyawaki T, Nonoyama S.
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: 128(e2) Pages: 223-225
- Data Source
  KAKENHI-PROJECT-23591561
[Journal Article] A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors2011
- Author(s)
  Niwa A, Heike T, Umeda K, et al.
- Journal Title
  
  PloS One
  
  Volume: 6 Issue: 7 Pages: e22261-e22261
- DOI
  10.1371/journal.pone.0022261
- NAID
  120003324603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591360, KAKENHI-PROJECT-22249042, KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-22790979, KAKENHI-PROJECT-23591561, KAKENHI-PROJECT-23657147
[Journal Article] A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors2011
- Author(s)
  Niwa A, Heike T, Umeda K, Oshima K, Kato I,Sakai H, Suemori H, Nakahata T, Saito MK.
- Journal Title
  
  PLoS One
  
  Volume: 6
- NAID
  120003324603
- Data Source
  KAKENHI-PROJECT-23591561
[Journal Article] Clinical and host genetic characteristics of Mendelian susceptibility to mycobacterial diseases in Japan2011
- Author(s)
  Hoshina T, Takada H, Sasaki-Mihara Y, Kusuhara K, Oshima K, Okada S, Kobayashi M, Ohara O, Hara T
- Journal Title
  
  J Clin Immunol
  
  Volume: 31 Pages: 309-314
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Quantification of κ-deleting recombination excision circles in Guthrie cards for the identification of early B-cell maturation defects2011
- Author(s)
  Nakagawa N, Imai K, Kanegane H, Sato H, Yamada M, Kondoh K, Okada S, Kobayashi M, Agematsu K, Takada H, Mitsuiki N, Oshima K, Ohara O, Suri D, Rawat A, Singh S, Pan-Hammarstrom Q, Hammarstrom L, Reichenbach J, Seger R, Ariga T, Hara T, Miyawaki T, Nonoyama S
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: 128 Pages: 223-225
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] Clinical and host genetic characteristics of Mendelian susceptibility to mycobacterial diseases in Japan2011
- Author(s)
  Hoshina T, Takada H, Sasaki-Mihara Y, Kusuhara K,Oshima K, Okada S, Kobayashi M, Ohara O,Hara T.
- Journal Title
  
  Clin Immunol
  
  Volume: 31 Pages: 309-314
- Data Source
  KAKENHI-PROJECT-23591561
[Journal Article] Novel mutations of MVK gene in Japanese family members affected with hyperimmunog lobulinemia D and periodic fever syndrome2011
- Author(s)
  Mizuno, T., H. Sakai, R. Nishikomori, K. Oshima, O. Ohara, I. Hata, Y. Shigematsu, T. Ishige, K. Tamura, and H. Arakawa
- Journal Title
  
  Rheumatol Int
  
  Volume: (in press) Issue: 12 Pages: 3761-3764
- DOI
  10.1007/s00296-011-2225-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390310, KAKENHI-PROJECT-23591561
[Journal Article] Novel mutations of MVK gene in Japanese family members affected with hyperimmunoglobulinemia D and periodic fever syndrome2011
- Author(s)
  Mizuno T, Sakai H, Nishikomori R, Oshima K,Ohara O, Hata I, Shigematsu Y, Ishige T, Tamura K, Arakawa H.
- Journal Title
  
  Arthritis Rheum
  
  Volume: 63 Pages: 3625-3632
- Data Source
  KAKENHI-PROJECT-23591561
[Journal Article] Rapid diagnosis of FHL3 by flow cytometric detection of intraplatelet Munc13-4 protein2011
- Author(s)
  Murata Y, Yasumi T, Shirakawa R, Izawa K, Sakai H, Abe J, Tanaka N, Kawai T, Oshima K, Saito M, Nishikomori R, Ohara O, Ishii E, Nakahata T, Horiuchi H, Heike T.
- Journal Title
  
  Blood
  
  Volume: 118 Pages: 1225-1230
- Data Source
  KAKENHI-PROJECT-23591561
[Journal Article] Clinical and host genetic characteristics of Mendelian susceptibility to mycobacterial diseases in Japan2011
- Author(s)
  Hoshina T, Takada H, et al
- Journal Title
  
  J Clin Immunol
  
  Volume: 31 Issue: 3 Pages: 309-314
- DOI
  10.1007/s10875-010-9498-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591363, KAKENHI-PROJECT-22790987, KAKENHI-PROJECT-23591559, KAKENHI-PROJECT-23591561
[Journal Article] Quantification of κ-deleting recombination excision circles in Guthrie cards for the identification of early B-cell2011
- Author(s)
  Nakagawa N,…, Takada H, et al
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: 128 Issue: 1 Pages: 223-225
- DOI
  10.1016/j.jaci.2011.01.052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591363, KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-23591561
[Journal Article] Rapid diagnosis of familial hemophagocytic lymphohistiocytosis type 3 (FHL3) by flow cytometric detection of intraplatelet Munc 13-4 protein2011
- Author(s)
  Murata Y., Yasumi T., Shirakawa R., Izawa K., Sakai H., Abe J., Tanaka N., Kawai T., Oshima K., Saito M., Nishikomori R., Ohara O., Ishii E., Nakahata T., Horiuchi H., Heike T.
- Journal Title
  
  Blood
  
  Volume: 118 Pages: 1225-1230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249042
[Journal Article] Clinical and host genetic characteristics of Mendelian susceptibility to mycobacterial diseases in Japan2011
- Author(s)
  Hoshina T, Takada H, Sasaki-Mihara Y, Kusuhara K, Oshima K, Okada S, Kobayashi M, Ohara O, Hara T
- Journal Title
  
  J Clin Immunol
  
  Volume: 31 Pages: 309-314
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390213
[Journal Article] Rapid diagnosis of FHL3 by flow cytometric detection of intraplatelet Munc13-4 protein2011
- Author(s)
  Murata Y, Yasumi T, Shirakawa R, Izawa K, Sakai H, Abe J, Tanaka N, Kawai T, Oshima K, Saito M, Nishikomori R, Ohara O, Ishii E, Nakahata T, Horiuchi H, Heike T
- Journal Title
  
  Blood
  
  Volume: 118 Pages: 1225-1230
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021049
[Journal Article] A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors2011
- Author(s)
  Niwa A., Heike T., Umeda K., Oshima K., Kato I., Sakai H., Suemori H., Nakahata T., Saito M.
- Journal Title
  
  PLoS ONE
  
  Volume: 6
- NAID
  120003324603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249042
[Journal Article] Quantification of K-deleting recombination excision circles in Guthrie cards for the identification of early B-cell maturation defects.2011
- Author(s)
  Nakagawa N, Imai K, Kanegane H, Sato H, Yamada M, Kondoh K, Okada S, Kobayashi M, Agematsu K, Takada H, Mitsuiki N, Oshima K, Ohara O, Suri D, Rawat A, Singh S, Pan-Hammarstrom Q, Hammarstrom L, Reichenbach J, Seger R, Ariga T, Hara T, Miyawaki T, Nonoyama S.
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: (未定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791018
[Journal Article] High incidence of NLRP3 somatic mosaicism in patients with chronic infantile neurologic, cutaneous, articular syndrome2011
- Author(s)
  Tanaka N, Izawa K, Saito MK, Sakuma M, Oshima K, Ohara O, Nishikomori R, Morimoto T, Kambe N, Goldbach-Mansky R, Aksentijevich I, de Saint Basile G, Neven B, van Gijn M, Frenkel J, Arostegui JI, Yague J, Merino R, Ibanez M, Pontillo A, Takada H, Imagawa T
- Journal Title
  
  Arthritis Rheum
  
  Volume: 63 Issue: 11 Pages: 3625-32
- DOI
  10.1002/art.30512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390310, KAKENHI-PROJECT-21591363, KAKENHI-PUBLICLY-22021049, KAKENHI-PROJECT-22249042, KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-23249056
[Journal Article] Hematopoietic stem cell transplantation in patients with severe congenital neutropenia:An analysis of 18 Japanese cases.2010
- Author(s)
  Oshima K, Hanada R, Kobayashi R, Kato K, Nagatoshi Y, Tabuchi K, Kato S.
- Journal Title
  
  Pediatr Transplant. 14
  
  Pages: 657-663
- Data Source
  KAKENHI-PROJECT-21791018
[Journal Article] A case of familial Mediterranean fever associated with compound heterozygosity for the pyrin variant L110P-E148Q/M680I in Japan2010
- Author(s)
  Oshima K, Yamazaki K, Nakajima Y, Kobayashi A, Kato T, Ohara O, Agematsu K
- Journal Title
  
  Modern Rheumatology
  
  Volume: 20 Pages: 193-195
- NAID
  10027169046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791018
[Journal Article] A case of familial Mediterranean fever associated with compound heterozygosity for the pyrin variant L110P-E148Q/M680I in Japan.2010
- Author(s)
  Oshima K, Yamazaki K, Nakaiima Y, Kobayashi A, Kate T, Ohara O, Agematsu K.
- Journal Title
  
  Mod Rheumatol. 20
  
  Pages: 193-195
- NAID
  10027169046
- Data Source
  KAKENHI-PROJECT-21791018
[Journal Article] Hematopoietic stem cell transplantation in patients with severe congenital neutropenia : An analysis of 18 Japanese cases2010
- Author(s)
  Oshima K, Hanada R, Kobayashi R, Kato K, Nagatoshi Y, Tabuchi K, Kato S
- Journal Title
  
  Pediatric Transplantation
  
  Volume: 14 Pages: 657-663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791018
[Presentation] Genetic analysis for 207 cases with primary immunodeficiency (PID) consulted to a single center through PID network in Japan (PIDJ) in 5 years (2007-2011).2012
- Author(s)
  Mitsuiki N, Oshima K, Imai K, Ohara O, Morio T, Mizutani S.
- Organizer
  15th Biennial Meeting of the European Society of Immunodeficiencies (ESID2012)
- Place of Presentation
  Florence, Italy.
- Data Source
  KAKENHI-PROJECT-22390213
[Presentation] HUMAN ESC/IPSC-DERIVED MESENCHYMAL STROMA CAN SUPPORT HEMATOPOIETIC PROGENITORS.2012
- Author(s)
  Niwa A., Saito M., Oshima K., Yanagimachi M., Tanaka T., Kato I., Nakahata,T.
- Organizer
  10th Annual Meeting of International Society for Stem Cell Research (ISSCR)
- Place of Presentation
  Pacifico Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-22249042
[Presentation] Differentiation of monocytic lineage cells from human iPS cells by using a serum and feeder free culture method.2012
- Author(s)
  Yanagimachi M, Niwa A, Tanaka T Oshima K, Saito M Nakahata T
- Organizer
  10th Annual Meeting of International Society for Stem Cell Research (ISSCR)
- Place of Presentation
  Pacifico Yokohama
- Data Source
  KAKENHI-PROJECT-24659496
[Presentation] DIFFERENTIATION OF MONOCYTIC LINEAGE CELLS FROM HUMAN IPS CELLS BY USING A SERUM AND FEEDER FREE CULTURE METHOD2012
- Author(s)
  Yanagimachi M., Niwa A., Tanaka T., Oshima K., Saito M., Nakahata T.
- Organizer
  10th Annual Meeting of International Society for Stem Cell Research (ISSCR)
- Place of Presentation
  Pacifico Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-22249042
[Presentation] Genetic analysis for 207 cases with primary immunodeficiency (PID) consulted to a single center through PID network in Japan (PIDJ) in 5 years (2007-2011)2012
- Author(s)
  Mitsuiki N, Oshima K, Imai K, Ohara O, Morio T,Mizutani S.
- Organizer
  15th Biennial Meeting of the European Society of Immunodeficiencies (ESID2012)
- Place of Presentation
  Florence,Italy
- Year and Date
  2012-10-05
- Data Source
  KAKENHI-PROJECT-23591561
[Presentation] Human ESC/IPSC-Derived mesenchymal stroma can support hematopoietic progenitors2012
- Author(s)
  Niwa A., Saito M., Oshima K., Yanagimachi M., Tanaka T., Kato I., Nakahata T.
- Organizer
  10◎<th>◎ Annual Meeting of International Society for Stem Cell Research (ISSCR)
- Place of Presentation
  Pacifico Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-24659496
[Presentation] Genetic analysis for 207 cases with primary immunodeficiency (PID) consulted to a single center through PID network in Japan (PIDJ) in 5 years (2007-2011)2012
- Author(s)
  Mitsuiki N, Oshima K, Imai K, Ohara O, Morio T, Mizutani S
- Organizer
  15th Biennial Meeting of the European Society of Immunodeficiencies (ESID2012)
- Place of Presentation
  Florence, Italy
- Data Source
  KAKENHI-PROJECT-22390213
[Presentation] 白血球減少、骨髄異形成とリンパ浮腫を呈するGATA-2異常2012
- Author(s)
  石田宏之、今井耕輔、本間健一、田村真一、今村俊彦、斎藤潤、大嶋宏一、伊藤雅文、中畑龍俊、野々山恵章
- Organizer
  第115回日本小児科学学術集
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24659496
[Presentation] Differentiation of monocytic lineage cells from human iPS cells by using a serum and feeder free culture method2012
- Author(s)
  Yanagimachi M., Niwa A., Tanaka T. Oshima K., Saito M., Nakahata T.
- Organizer
  10◎<th>◎ Annual Meeting of International Society for Stem Cell Research (ISSCR)
- Place of Presentation
  Pacifico Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-24659496
[Presentation] Human ESC/IPSC-Derived mesenchymal stroma can support hematopoietic progenitors.2012
- Author(s)
  Niwa A, Saito M, Oshima K, Yanagimachi M, Tanaka T, Kato I, Nakahata T
- Organizer
  10th Annual Meeting of International Society for Stem Cell Research (ISSCR)
- Place of Presentation
  Pacifico Yokohama
- Data Source
  KAKENHI-PROJECT-24659496
[Presentation] NLRP3体細胞モザイクはCINCA症候群の25%以上に認められる2011
- Author(s)
  田中尚子、井澤和司、斎藤潤、作間未織、大嶋宏一、小原収、西小森隆太、森本剛、中畑龍俊、平家俊男
- Organizer
  第114回日本小児科学会学術集会
- Place of Presentation
  グランドプリンスホテル新高輪(東京都)
- Year and Date
  2011-08-13
- Data Source
  KAKENHI-PROJECT-22249042
[Presentation] Genetic analysis for 207 cases with primary immunodeficiency (PID) consulted to a single center through PID network in Japan (PIDJ) in 5 years (2007-2011).
- Author(s)
  Mitsuiki N, Oshima K, Imai K, Ohara O, Morio T, Mizutani S.
- Organizer
  15th Biennial Meeting of the European Society of Immunodeficiencies (ESID2012)
- Place of Presentation
  Florence,Italy
- Data Source
  KAKENHI-PROJECT-23591561

1. IMAI Kohsuke (90332626)

# of Collaborated Projects: 4 results

# of Collaborated Products: 15 results
2. NONOYAMA Shigeaki (40280961)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
3. OHARA Osamu (20370926)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
4. NAKAHATA Tatsutoshi (20110744)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
5. NIWA Akira (20546999)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
6. SAITO Megumu (90535486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HIJIKATA Atsushi (80415273)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 長瀬隆弘 (10211442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SAITOH Megumu

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
10. YABE Miharu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. YABE Hiromasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. KATO Shunichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 平家俊男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 西小森隆太

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. 高田英俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. 神戸直智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Oshima Koichi 大嶋 宏一

OSHIMA Koichi 大嶋 宏一

Research Projects

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Genome-wide CRISPR/Cas9 screening for drug target discovery in neuroblastomaPrincipal Investigator

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Hematopoietic stem cell potential is propagated by human pluripotent stem cell-derived endothelial stroma

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Analysis of pathophysiology and identification of the causative gene(s) of primary immunodeficiency with B, NK, dendritic cell deficiency

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疾患特異的iPS細胞を用いた細網異形成症の病態解析Principal Investigator

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自己識別機構の破綻をきたす免疫不全症の病態解明と原因遺伝子同定

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Recapitulation of phenotypes and discovery of a novel treatment with disease-specific human ES/ iPS cells from various hereditary diseases

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Research for developing of a screening method for the congenital immunodeficiency by KREC/TREC to apply the method to the pathologic analysis

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Development of easy and cost-effective mass-screening of severe combined immunodeficiency using neonatal guthrie cards.Principal Investigator

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[Journal Article] The role of CRISPR screening in leukemia research2022

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[Journal Article] Robust and highly-efficient differentiation of functional monocytic cells from human pluripotent stem cells under serum- and feeder cell- free conditions.2013

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[Journal Article] Kasabach-Merritt Phenomenon: A Report of 11 Cases From a Single Institution.2013

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[Journal Article] GATA-2 anomaly and clinical phenotype of a sporadic case of lymphedema, dendritic cell, monocyte, B- and NK-cell (DCML) deficiency, and myelodysplasia2012

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[Journal Article] Matched sibling donor stem cell transplantation for Fanconi anemia patients with T-cell somatic mosaicism2012

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Oshima Koichi 大嶋宏一

OSHIMA Koichi 大嶋宏一