HIRATA Akira 平田章

Researcher Number	60527381
Other IDs	https://orcid.org/0000-0001-9941-3793
Affiliation (Current)	2025: 徳島大学, 大学院社会産業理工学研究部(理工学域), 准教授
Affiliation (based on the past Project Information) *help	2024: 徳島大学, 大学院社会産業理工学研究部(理工学域), 准教授 2020 – 2022: 徳島大学, 大学院社会産業理工学研究部(理工学域), 准教授 2016 – 2019: 愛媛大学, 理工学研究科(工学系), 講師 2012 – 2015: 愛媛大学, 理工学研究科, 講師 2013: 愛媛大学, 大学院・理工学研究科, 講師 … More 2012: 愛媛大学, 理工学研究科, 助教 2011: 愛媛大学, 大学院・理工学研究科, 助教 2009 – 2010: Ehime University, 理工学研究科, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 43020:Structural biochemistry-related / Biological Sciences / Functional biochemistry / Structural biochemistry Except Principal Investigator Basic Section 43030:Functional biochemistry-related / Chemistry related to living body
Keywords	Principal Investigator アーキア / X線結晶構造解析 / RNA成熟 / tRNA修飾 / tRNA modification / 転写 / RNAポリメラーゼ / 酵素複合体 / ラジカルSAM / 連続触媒反応機構 … More / tRNA修飾酵素 / tRNA耐熱化機構 / 超好熱菌 / tRNAメチル化酵素 / 耐熱化機構 / Archaea / tRNA modification enzyme / thermotolerant RNA / 電子顕微鏡 / 転写活性化因子 / 転写開始前複合体 / 動的分子認識機構 / X線溶液散乱 / tRNAスプライシング / 基質認識 / tRNA成熟 / 酵母 / RNA splicing / tRNA methyltransferase / SAXS analysis / X-ray structure / recognition mechanism / tRNA maturation / RNA ポリメラーゼ / 遺伝子発現 / 生命進化 / 生化学 / 遺伝学 / 構造生物学 / アーキア（古細菌） / RNA成熟マシナリー / tRNAプロセシング / 酵素の生理機能 / 酵素の基質認識機構 / 古細菌 / 基質認識機構 / RNA修飾酵素 … More Except Principal Investigator RNA / タンパク質 / 酵素 / 核酸 / 構造解析 / ゲノム / RNA分解制御 / メチル化酵素 / tRNA / RNAメチル化 / RNA修飾 / ＲＮＡ Less

酵素タンパク質複合体形成による二機能性触媒反応メカニズムの構造基盤Principal Investigator
- Principal Investigator
  
  平田章
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  The University of Tokushima
Study on substrate tRNA recognition mechanisms of multiple subunit tRNA modification enzymes
- Principal Investigator
  
  Hori Hiroyuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Ehime University
Elucidation of thermotolerant mechanism of the RNA essential for life activity under high-temperature environmentPrincipal Investigator
- Principal Investigator
  
  HIRATA Akira
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  The University of Tokushima
  Ehime University
Elucidation of dynamic-molecular recognition mechanism by the dimeric RNA maturation enzymesPrincipal Investigator
- Principal Investigator
  
  Hirata Akira
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Ehime University
アーキアの転写装置を利用した多段階転写反応の動的メカニズムの解明Principal Investigator
- Principal Investigator
  
  平田章
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Ehime University
アーキア（古細菌）RNAポリメラーゼにおける転写開始機構および転写調節機構の解明Principal Investigator
- Principal Investigator
  
  平田章
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Ehime University
Elucidation of mechanism of molecular dynamics recognition by RNA machineries involved in the thermostable RNA maturationPrincipal Investigator
- Principal Investigator
  
  HIRATA Akira
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Ehime University
Structural basis and functional evolution of RNA maturation machinary
- Principal Investigator
  
  HORI Hiroyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Ehime University
RNA修飾酵素の基質認識機構の統一的パラダイムの構築Principal Investigator
- Principal Investigator
  
  平田章
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Ehime University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book

[Book] アーキア生物学2017
- Author(s)
  日本Archaea研究会、石野良純、跡見晴幸、平田　章（執筆分担）
- Total Pages
  212
- Publisher
  共立出版
- ISBN
  9784320057852
- Data Source
  KAKENHI-PROJECT-15K06975
[Journal Article] Required Elements in tRNA for Methylation by the Eukaryotic tRNA (Guanine- N2-) Methyltransferase (Trm11-Trm112 Complex)2022
- Author(s)
  Yu Nishida, Shiho Ohmori, Risa Kakizono, Kunpei Kawai, Miyu Mamba, Kazuki Okada, Ryota Yamagami, Akira Hirata, Hiroyuki Hori
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 7 Pages: 4046-4046
- DOI
  10.3390/ijms23074046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03211
[Journal Article] Distinct Modified Nucleosides in tRNATrp from the Hyperthermophilic Archaeon Thermococcus kodakarensis and Requirement of tRNA m2G10/m22G10 Methyltransferase (Archaeal Trm11) for Survival at High Temperatures2019
- Author(s)
  Hirata Akira、Suzuki Takeo、Nagano Tomoko、Fujii Daishiro、Okamoto Mizuki、Sora Manaka、Lowe Todd M.、Kanai Tamotsu、Atomi Haruyuki、Suzuki Tsutomu、Hori Hiroyuki
- Journal Title
  
  Journal of Bacteriology
  
  Volume: 201 Issue: 21 Pages: 1-17
- DOI
  10.1128/jb.00448-19
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06088, KAKENHI-PROJECT-19K22246, KAKENHI-PROJECT-18H02094, KAKENHI-PROJECT-18H05272
[Journal Article] Structure of tRNA methyltransferase complex of Trm7 and Trm734 reveals a novel binding interface for tRNA recognition2019
- Author(s)
  Hirata Akira、Okada Keisuke、Yoshii Kazuaki、Shiraishi Hiroyuki、Saijo Shinya、Yonezawa Kento、Shimizu Nobutaka、Hori Hiroyuki
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 47 Issue: 20 Pages: 10942-10955
- DOI
  10.1093/nar/gkz856
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06088, KAKENHI-PLANNED-19H05781
[Journal Article] Identification of a radical SAM enzyme involved in the synthesis of archaeosine2019
- Author(s)
  Yokogawa Takashi、Nomura Yuichiro、Yasuda Akihiro、Ogino Hiromi、Hiura Keita、Nakada Saori、Oka Natsuhisa、Ando Kaori、Kawamura Takuya、Hirata Akira、Hori Hiroyuki、Ohno Satoshi
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 15 Issue: 12 Pages: 1148-1155
- DOI
  10.1038/s41589-019-0390-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06088, KAKENHI-PROJECT-19K05692, KAKENHI-PROJECT-17K05781, KAKENHI-PROJECT-17K05929
[Journal Article] Recent Insights Into the Structure, Function, and Evolution of the RNA-Splicing Endonucleases2019
- Author(s)
  Hirata Akira
- Journal Title
  
  Frontiers in Genetics
  
  Volume: 10 Pages: 1-7
- DOI
  10.3389/fgene.2019.00103
- NAID
  120006953546
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06088
[Journal Article] The RNA-splicing endonuclease from the euryarchaeaon Methanopyrus kandleri is a heterotetramer with constrained substrate specificity2018
- Author(s)
  Kaneta Ayano、Fujishima Kosuke、Morikazu Wataru、Hori Hiroyuki、Hirata Akira
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 46 Issue: 4 Pages: 1958-1972
- DOI
  10.1093/nar/gky003
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06975
[Journal Article] A structural sketch of RcdA, a transcription factor controlling the master regulator of biofilm formation2017
- Author(s)
  Sugino Hirotaka、Usui Takanori、Shimada Tomohiro、Nakano Masahiro、Ogasawara Hiroshi、Ishihama Akira、Hirata Akira
- Journal Title
  
  FEBS Lett.
  
  Volume: 591 Issue: 13 Pages: 2019-2031
- DOI
  10.1002/1873-3468.12713
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06975, KAKENHI-PROJECT-15K18670
[Journal Article] Structural and functional analyses of the archaeal tRNA m2G/m22G10 methyltransferase aTrm11 provide mechanistic insights into the site specificity of a tRNA methyltransferase that contains common RNA-binding modules.2016
- Author(s)
  A. Hirata, S. Nishiyama, T. Tamura, A. Yamauchi, and H. Hori
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 44 Issue: 13 Pages: 6377-6390
- DOI
  10.1093/nar/gkw561
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H04763, KAKENHI-PROJECT-15K06975
[Journal Article] The X-ray crystal structure of the euryarchaeal RNA polymerase in an open clamp configuration2014
- Author(s)
  Sung-Hoon Jun, Akira Hirata*, Tamotsu Kanai, Thomas J. Santangelo, Tadayuki Imanaka and Katsuhiko S. Murakami*
- Journal Title
  
  Nature Communications
  
  Volume: 5 Issue: 1 Pages: 5132-5132
- DOI
  10.1038/ncomms6132
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25118516, KAKENHI-PROJECT-26292038
[Journal Article] The catalytic domain of topological knot tRNA methyltransferase (TrmH) discriminates between substrate tRNA and nonsubstrate tRNA via an induced-fit process2013
- Author(s)
  A. Ochi, K. Makabe, R. Yamagami, A. Hirata, R. Sakaguchi, Y.M. Hou, K. Watanabe, O. Nureki, K. Kuwajima, and H. Hori
- Journal Title
  
  J. Biol. Chem
  
  Volume: 288 Pages: 25562-25574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23350081
[Journal Article] The catalytic domain of topological knot tRNA methyltransferase (TrmH) discriminates between substrate tRNA and nonsubstrate tRNA via an induced-fit process.2013
- Author(s)
  A. Ochi, K. Makabe, R. Yamagami, A. Hirata, R. Sakaguchi, Y.M. Hou, K. Watanabe, O. Nureki, K. Kuwajima, and H. Hori
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 35 Pages: 25562-25574
- DOI
  10.1074/jbc.m113.485128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23350081, KAKENHI-PROJECT-23770194, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25440075
[Journal Article] The tRNA recognition mechanism of folate/FAD-dependent tRNA methyltransferase (TrmFO)2012
- Author(s)
  R. Yamagami, K. Yamashita, H. Nishimasu, C. Tomikawa, A. Ochi, C. Iwashita, A. Hirata, R. Ishitani, O. Nureki, and H. Hori
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287 Pages: 42480-42494
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23350081
[Journal Article] X-ray structure of the fourth type of archaeal tRNA splicing endonuclease : insight into the evolution of a novel three-unit composition and a unique loop involved in broad substrate specificity2012
- Author(s)
  A. Hirata, K. Fujishima, R. Yamagami, T. Kawamura, J. F. Banfield, A. Kanai, and H. Hori
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 40 Pages: 10554-10566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23350081
[Journal Article] The tRNA recognition mechanism of folate/FAD-dependent tRNA methyltransferase (TrmFO)2012
- Author(s)
  Yamagami R, Yamashita K, Nishimasu H, Tomikawa C, Ochi A, Iwashita C, Hirata A, Ishitani R, Nureki O, Hori H
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Issue: 51 Pages: 42480-42480
- DOI
  10.1074/jbc.m112.390112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687007, KAKENHI-PROJECT-23350081, KAKENHI-PROJECT-23687014, KAKENHI-PROJECT-24655156
[Journal Article] X-ray structure of the fourth type of archaeal tRNA splicing endonuclease: insight into the evolution of a novel three-unit composition and a unique loop involved in broad substrate specificity.2012
- Author(s)
  A. Hirata, K. Fujishima, R. Yamagami, T. Kawamura, J. F. Banfield, A. Kanai, and H. Hori
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 40 Issue: 20 Pages: 10554-10566
- DOI
  10.1093/nar/gks826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23350081, KAKENHI-PROJECT-24770125
[Journal Article] Cleavage of intron from the standard or non-standard position of the precursor tRNA by the splicing endonuclease of Aeropyrum pernix, a hyper-thermophilic Crenarchaeon, involves a novel RNA recognition site in the Crenarchaea specific loop2011
- Author(s)
  A. Hirata, T. Kitajima, and H. Hori
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 39 Pages: 9376-9389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23350081
[Journal Article] Substrate tRNA recognition mechanism of a multisite-specific tRNA methyltransferase, Aquifex aeolicus Trm1, based on the X-ray crystal structure2011
- Author(s)
  Awai T., et al
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Issue: 40 Pages: 35236-35246
- DOI
  10.1074/jbc.m111.253641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21603018, KAKENHI-PROJECT-23350081
[Journal Article] Cleavage of intron from the standard or non-standard position of the precursor tRNA by the splicing endonuclease of Aeropyrum pernix, a hyper-thermophilic Crenarchaeon, involves a novel RNA recognition site in the Crenarchaea specific loop2011
- Author(s)
  A.Hirata, T.Kitajima, H.Hori
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 39 Issue: 21 Pages: 9376-9389
- DOI
  10.1093/nar/gkr615
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23350081
[Journal Article] Substrate tRNA recognition mechanism of a multi-site-specific tRNA methyltransferase, Aquifex aeolicus Trm1, based on the X-ray crystal structure2011
- Author(s)
  T. Awai, A. Ochi, Ihsanawati, T. Sengoku, A. Hirata, Y. Bessho, S. Yokoyama, and H. Hori
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Pages: 35236-35246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23350081
[Journal Article] Pseudouridine at position 55 (Ψ55) in tRNA controls the contents of other modified nucleotides for low-temperature adaptation in the extreme-thermophilic eubacterium Thermus thermophilus2011
- Author(s)
  K. Ishida, T. Kunibayashi, C. Tomikawa, A. Ochi, T. Kanai, A. Hirata, C. Iwashita, and H. Hori
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 39 Pages: 2304-2318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Required Elements in tRNA for Methylation by the Eukaryotic tRNA (Guanine-N2-) Methyltransferase (Trm11-Trm112 Complex)2022
- Author(s)
  Kumpei Kawai, Yu Nishida, Shiho Ohmori, Risa Kakizono, Miyu Namba, Kazuki Okada, Ryota Yamagami, Akira Hirata, Hiroyuki Hori
- Organizer
  第23回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-20H03211
[Presentation] Enzymatic properties of Thermoplasma acidophilum Trm56, which has the longest C-terminal region in the SPOUT RNA methyltransferase superfamily2022
- Author(s)
  Hiroyuki Hori, Shyuhei Fukumoto, Takahiro Hasegawa, Mami Ototake, Shizuka Moriguchi, Miyu Namba, Ryota Yamagami, Takuya Kawamura, Akira Hirata
- Organizer
  第23回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-20H03211
[Presentation] 超好熱性アーキアThermococcus kodakarensis由来tRNA メチル化酵素Trm14の機能解明について2021
- Author(s)
  野利本剛, 空磨奈伽, 平田章, 堀弘幸
- Organizer
  第33回日本Archaea研究会講演会
- Data Source
  KAKENHI-PROJECT-20H03211
[Presentation] 超好熱性アーキアThermococcus kodakarensis由来tRNA m2G6 メチル化酵素Trm14の幅広い基質特異性2021
- Author(s)
  野利本剛, 空磨奈伽, 平田章, 堀弘幸
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03211
[Presentation] Escherichia coli tRNA (Gm18) methyltransferase (TrmH) recognizes the location of methylation site (G18) in the D-loop for the selection of substrate tRNA.2021
- Author(s)
  Yoh Kohno, Asako Ito, Aya Okamoto, Ryota Yamagami, Akira Hirata, Hiroyuki Hori
- Organizer
  第22回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-20H03211
[Presentation] SpoU-TrmD RNAメチル化酵素スーパーファミリーの中で、最も長いC末領域を持つThermoplasma acidophilum Trm56の新しい精製法2020
- Author(s)
  堀　弘幸、福本修平、長谷川貴宏、難波美優、平田　章、河村卓哉
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06088
[Presentation] 超好熱性アーキアThermococcus kodakarensis 由来tRNAメチル化酵素Trm14の研究2020
- Author(s)
  野利本剛、平田　章、空　まかな、堀　弘幸
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06088
[Presentation] アーキア特異的修飾ヌクレオシド、アーケオシンの合成に関わる新奇ラジカルSAM酵素2019
- Author(s)
  横川隆志 , 能村友一朗 , 安田旭宏 , 尾木野弘実 , 日浦恵太 , 仲田沙織 , 岡夏央 , 安藤香織 , 河村卓哉 , 平田章 , 堀弘幸 , 大野敏
- Organizer
  第42回日本分子生物学会年会　福岡
- Data Source
  KAKENHI-PROJECT-18K06088
[Presentation] Analysis of distinct modified nucleosides in tRNA from the hyperthermophilic archaeon Thermococcous kodakarensis provides insight into the requirement of specific tRNA modifications and their responsible genes for survival at high temperatures2019
- Author(s)
  Hirata, A , Suzuki, T , Nagano, T , Fuji, D , Okamoto, M , Sora, M , Lowe, M. T , Kanai, T , Atomi, H , Suzuki, T , Hori H
- Organizer
  Thermophiles2019 福岡
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06088
[Presentation] (超）好熱性アーキアのRNA修飾の研究2019
- Author(s)
  平田　章
- Organizer
  微生物ウィーク2019 東京大学農学部弥生講堂
- Invited
- Data Source
  KAKENHI-PROJECT-18K06088
[Presentation] Structure of tRNA methyltransferase complex of Trm7 and Trm734 provides insight into its novel bipartite interaction essential for tRNA recognition and 2´-O-methylation at the first position of anticodon in specific tRNAs2019
- Author(s)
  Hirata, A , Okada, K , Yoshi, K , Shiraishi, H , Saijo, S , Yonezawa, K , Shimizu, N , Hori, H
- Organizer
  第21回日本RNA学会年会東京大学伊藤国際学術研究センター
- Data Source
  KAKENHI-PROJECT-18K06088
[Presentation] 大腸菌tRNA (Gm18) メチル化酵素（TrmH)の基質tRNA選択システム2018
- Author(s)
  河野　陽、伊藤亜沙子、山上龍太、平田　章、堀　弘幸
- Organizer
  第20回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-18K06088
[Presentation] The RNA-splicing endonuclease from the Euryarchaea Methanopyrus kandleri uniquely represents a heterodimer with constraint range of substrate specificity: Supporting the coevolutionary scenario of protein function and tRNA gene diversity2018
- Author(s)
  Kaneta, A., Fujishima, K., Morikazu, W., Hori, H., and Hirata, A.
- Organizer
  extremophiles 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06088
[Presentation] Methanosarcina acetivoransにおける修飾ヌクレオシドアーケオシン生合成経路の解明2018
- Author(s)
  日浦恵太、能村友一朗、安田旭宏、大野　敏、尾木野弘実、河村卓哉、平田　章、堀　弘幸、横川隆志
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06088
[Presentation] Structure of yeast tRNA Nm34 methyltransferase Trm7-Trm734 complex reveals its novel bipartite interaction essential for 2'-O-methylation of N34 in the wobble position of three specific tRNA species2018
- Author(s)
  Hirata, A., Okada, K., Yoshii, K., Shiraishi, H., Saijo, S., Yonezawa, K., Shimizu, N., and Hori, H.
- Organizer
  27th tRNA Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06088
[Presentation] tRNA成熟化機構に見られるアーキアの生存戦略2017
- Author(s)
  平田　章
- Organizer
  環境微生物系学会合同大会2017
- Invited
- Data Source
  KAKENHI-PROJECT-15K06975
[Presentation] 超好熱性アーキアのtRNA修飾、特にメチル化修飾は高温環境下の生育にとって必須である2017
- Author(s)
  平田　章
- Organizer
  第30回日本Archaea研究会
- Data Source
  KAKENHI-PROJECT-15K06975
[Presentation] 芳香族アミノ酸の生合成遺伝子群の発現を制御するアーキア転写活性化因子(Tar)の分子認識機構の解明2017
- Author(s)
  臼井孝典、金井保、跡見晴幸、堀弘幸、平田章
- Organizer
  第18回極限環境生物学会年会
- Data Source
  KAKENHI-PROJECT-15K06975
[Presentation] 真核生物tRNAメチル化酵素Trm7-Trm734複合体の活性発現メカニズムの構造基盤2017
- Author(s)
  平田　章、岡田　圭祐、吉井　一晃、白石　裕之、西條　慎也、米澤　健人、清水　伸隆、堀　弘幸
- Organizer
  生命科学系合同学会年次大会
- Data Source
  KAKENHI-PROJECT-15K06975
[Presentation] Structural and founctional analyses reveal mechanistic insight into a site specificity of the archaeal tRNA methyltransferase2016
- Author(s)
  Hirata A, Nishiyama S, Tamura T, Yamauchi A, and Hori H
- Organizer
  RNA2016
- Place of Presentation
  国立京都国際会館 (京都府京都市左京区）
- Year and Date
  2016-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06975
[Presentation] Insights derived from Molecular Dynamics Simulations into the subunit assembly and clamp motions of Thermococcus kodakarensis RNA polymerase2016
- Author(s)
  Mohan A, Kasahara, K, Hirata A and Nakamura H
- Organizer
  第16回日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場 (福岡県福岡市博多区）
- Year and Date
  2016-06-07
- Data Source
  KAKENHI-PUBLICLY-15H01357
[Presentation] Structural and functional analyses reveal mechanistic insight into a site specificity of the archaeal tRNA m2G/m22G10 methyltransferase (aTrm11)2016
- Author(s)
  Hirata A, Nishiyama S, Tamura T, Yamauchi A, and Hori H
- Organizer
  Extremophiles 2016
- Place of Presentation
  京都大学(京都府京都市左京区）
- Year and Date
  2016-09-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06975
[Presentation] 超好熱性アーキアMethanopyrus kandleri由来tRNA スプライシングエンドヌクレアーゼの基質認識に関する研究2016
- Author(s)
  金田綾乃、森数渉、堀弘幸、平田章
- Organizer
  第17回極限環境生物学会年会
- Place of Presentation
  東京工業大学すずかけ台キャンパス（神奈川県横浜市緑区）
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-15K06975
[Presentation] アーキアtRNA (m2G10/m22G10) メチル化酵素arcTrm11の基質認識機構の解明2015
- Author(s)
  平田　章、西山　聖示、田村　俊浩、山内　綾乃、堀　弘幸
- Organizer
  第16回極限環境生物学会
- Place of Presentation
  東京海洋大学（東京都港区）
- Year and Date
  2015-11-08
- Data Source
  KAKENHI-PROJECT-15K06975
[Presentation] X-ray crystal structure of euryarchaeal RNA polymerase (RNAP) from a hyperthermophilic archaeonThermococcus kodakarensis: Insights into the molecular evolution of the archaeal/eukaryotic RNAP and molecular mechanism underlying the clamp-open state in the presence of the stalk2015
- Author(s)
  平田　章、Sung-Hoon Jun、金井　保、Thomas J　Santangelo、今中　忠行、村上　勝彦
- Organizer
  Thermophiles2015
- Place of Presentation
  サンティアゴ大学（チリ共和国サンティアゴ）
- Year and Date
  2015-08-30
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01357
[Presentation] 転写制御に関わるアーキア及び真核生物 RNAポリメラーゼのクランプ構造の開閉機構2015
- Author(s)
  平田　章、Sung-Hoon Jun、金井　保、Thomas J　Santangelo、今中　忠行、村上　勝彦
- Organizer
  第15回日本蛋白質学会年会
- Place of Presentation
  あわぎんホール (徳島県徳島市)
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PUBLICLY-15H01357
[Presentation] 真核微生物由来tRNA(Gm34)メチル化酵素Trm7-Trm734の構造機能解析2015
- Author(s)
  岡田　圭祐、平田　章、吉井一晃、堀　弘幸
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートピアアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06975
[Presentation] アーキア由来tRNAm2G10/m22G10メチル化酵素arcTrm11のX線結晶構造～tRNA修飾酵素の部位特異性を決定している共通基本原理の統一的理解～2015
- Author(s)
  平田　章、西山　聖示、田村　俊浩、山内　綾乃、堀　弘幸
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートピアアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06975
[Presentation] Thermococcus kodakarensis 由来tRNA メチル化酵素(Trm- m22G10) の構造機能解析2013
- Author(s)
  西山聖示、平田章、田村俊浩、堀弘幸
- Organizer
  第14回極限環境生物学会年会
- Place of Presentation
  神奈川県
- Data Source
  KAKENHI-PROJECT-24770125
[Presentation] Eukaryotic tRNA (m2G10) methyltransferase (Trm11-Trm112) recognizes the whole structure of tRNA2013
- Author(s)
  Shiho Ohmori, Yu Nishida, Kazuki Okada, Akira Hirata, and Hiroyuki Hori
- Organizer
  第3回モデル生物丸ごと一匹学会年会
- Place of Presentation
  大阪大学豊中キャンパス
- Year and Date
  2013-09-21
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 葉酸依存性tRNA(m5U54)メチル化酵素TrmFOはどうやってtRNA中のU54を認識しているのか?2013
- Author(s)
  山上龍太, 山下光輝, 西増弘志, 冨川千恵, 越智杏奈, 岩下智香子, 平田章, 石谷隆一郎, 濡木理, 堀弘幸
- Organizer
  第15回日本RNA学会年会
- Place of Presentation
  松山
- Year and Date
  2013-07-24
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] X-ray crystal structure of the fourth type of tRNA splicing endonuclease from an uncultivated archaeon Candidatus Micrarchaeum acidiphilum (ARMAN-2)2013
- Author(s)
  Akira Hirata, Kosuke Fujishima, Ryota Yamagami, Takuya Kawamura, Jillian F. Banfiled, Akio Kanai and Hiroyuki Hori
- Organizer
  Thermophiles 2013
- Place of Presentation
  Deutschland
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 超好熱性アーキア Thermococcus kodakarensis 由来 tRNATrp の修飾ヌクレオシド分析2013
- Author(s)
  前田雄太、平田　章、長野倫子、土手智裕、鈴木健夫、金井　保、鈴木勉、堀　弘幸
- Organizer
  第14回極限環境生物学会年会
- Place of Presentation
  神奈川県
- Data Source
  KAKENHI-PROJECT-24770125
[Presentation] Thermococcus kodakarensis 由来tRNAメチル化酵素(Trm-m22G10)の構造機能解析2013
- Author(s)
  西山聖示, 平田章, 田村俊浩, 堀弘幸
- Organizer
  2013年度極限環境生物学会年会
- Place of Presentation
  明治大学生田キャンパス
- Year and Date
  2013-10-27
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Structural basis for transcription mechanism by Archaeal RNA polymerase2013
- Author(s)
  Akira Hirata
- Organizer
  新学術領域「転写サイクル」班会議
- Place of Presentation
  神奈川県
- Data Source
  KAKENHI-PUBLICLY-25118516
[Presentation] Thermococcus kodakarensis由来tRNAメチル化酵素(Trm- m22G10)の構造機能解析2013
- Author(s)
  西山聖示、平田章、田村俊浩、堀弘幸
- Organizer
  第14回極限環境生物学会年会
- Place of Presentation
  神奈川県
- Data Source
  KAKENHI-PROJECT-24770125
[Presentation] X-ray crystal structure of the fourth type of tRNA splicing endonuclease from an uncultivated archaeon Candidatus Micrarchaeum acidiphilum (ARMAN-2)2013
- Author(s)
  Akira Hirata, Kosuke Fujishima, Ryota Yamagamia, Takuya Kawamuraa, Jillian F. Banfiledd, Akio Kanaib and Hiroyuki Hori
- Organizer
  Thermophiles2013
- Place of Presentation
  ドイツ
- Data Source
  KAKENHI-PROJECT-24770125
[Presentation] 極小アーキア(古細菌)における4番目のタイプtRNAスプライシングエンドヌクレアーゼのX線結晶構造2013
- Author(s)
  平田章, 藤島皓介, 山上龍太, 河村卓哉, Jillina F. Banfield, 金井昭夫, 堀弘幸
- Organizer
  第13回蛋白質科学会
- Place of Presentation
  鳥取
- Year and Date
  2013-06-12
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Does D20 formation by eubacterial dihydrouridine synthase require the other modified nucleotides for its modification in tRNA?2013
- Author(s)
  楠葉浩晃, 吉田剛士, 岩崎絵梨, 粟井貴子, 平田章, 冨川千恵, 山上龍太, 堀弘幸
- Organizer
  第3回モデル生物丸ごと一匹学会年会
- Place of Presentation
  大阪大学豊中キャンパス
- Year and Date
  2013-09-21
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 真正細菌ジヒドロウリジン合成酵素はD20形成にtRNA上の他の修飾ヌクレオチドを必要とする2013
- Author(s)
  楠葉浩晃, 吉田剛士, 岩崎絵梨, 粟井貴子, 平田章, 冨川千恵, 山上龍太, 堀弘幸
- Organizer
  第15回日本RNA学会年会
- Place of Presentation
  松山
- Year and Date
  2013-07-24
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 超好熱性アーキアThermococcus kodakarensis 2´-5´RNAリガーゼの機能解析2013
- Author(s)
  平田章, 長野倫子, 石丸雄基, 金井保, 鈴木健夫, 佐藤朝子, 金井昭夫, 鈴木勉, 堀弘幸
- Organizer
  第15回日本RNA学会年会
- Place of Presentation
  松山
- Year and Date
  2013-07-24
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Yeast tRNA (m2G10) methyltransferase (Trm11-Trm112)の基質認識機構の解明2013
- Author(s)
  大森志穂, 西田裕, 岡田和樹, 平田章, 堀弘幸
- Organizer
  第15回日本RNA学会年会
- Place of Presentation
  松山
- Year and Date
  2013-07-24
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] X-ray crystal structure of the fourth type of tRNA splicing endonuclease from an uncultivated archaeon Candidatus Micrarchaeum acidiphilum (ARMAN-2)2013
- Author(s)
  Akira Hirata, Kosuke Fujishima, Ryota Yamagami, Takuya Kawamura, Jillian F. Banfiled, Akio Kanai and Hiroyuki Hori
- Organizer
  Thermophiles 2013
- Place of Presentation
  レジェンスブルク、ドイツ
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 超好熱性アーキアThermococcus kodakarensis由来tRNATrpの修飾ヌクレオシド分析2013
- Author(s)
  前田雄太、平田章、長野倫子、土手智裕、鈴木健夫、金井保、鈴木勉、堀弘幸
- Organizer
  第14回極限環境生物学会年会
- Place of Presentation
  神奈川県
- Data Source
  KAKENHI-PROJECT-24770125
[Presentation] 超好熱性アーキアThermococcus kodakarensis由来tRNATrpの修飾ヌクレオシド分析2013
- Author(s)
  前田雄太, 平田章, 長野倫子, 土手智裕, 鈴木健夫, 金井保, 鈴木勉, 堀弘幸
- Organizer
  2013年度極限環境生物学会年会
- Place of Presentation
  明治大学生田キャンパス
- Year and Date
  2013-10-27
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 極小アーキア(古細菌）における4番目のタイプtRNAスプライシングエンドヌクレアーゼのX線結晶構造2013
- Author(s)
  平田　章、藤島皓介、山上龍太、河村卓哉、Jillina F. Banfield、金井昭夫、堀　弘幸
- Organizer
  第１３回蛋白質科学会
- Place of Presentation
  鳥取
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Improvement of a protein purification method for nucleic acid-free in the case of recombinant tRNA (N2, N2-guanine)-dimethyltransferase (Trm1) from Aquifex aeolicus2012
- Author(s)
  S. Nishiyama, A. Hirata, T. Awai, and H. Hori
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Structural insight into the evolution and broad substrate specificity of the fourth type of tRNA splicing endonuclease2012
- Author(s)
  A. Hirata, K. Fujishima, R. Yamagami, T. Kawamura, J. F. Banfiled, A. Kanai, and H. Hori
- Organizer
  9th Extremophiles 2012
- Place of Presentation
  Spain
- Year and Date
  2012-09-09
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 高度好熱菌tRNA中のシュードウリジン55修飾は, 温度変化への適応因子として機能する2012
- Author(s)
  冨川千恵, 石田一雄, 国林貴史, 越智杏奈, 金井保, 平田章, 岩下知香子, 堀弘幸
- Organizer
  第14回日本RNA学会年会
- Place of Presentation
  仙台
- Year and Date
  2012-07-16
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Functional analysis of yeast tRNA (m2G10) methyltransferase (Trm11-Trm112)2012
- Author(s)
  Y. Nishida, K. Okada, A. Hirata, and H. Hori
- Organizer
  第2回モデル生物丸ごと一匹学会
- Place of Presentation
  SPring-8 (Harima)
- Year and Date
  2012-09-28
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Transfer RNA recognition mechanism of Thermus thermophilus folate/FAD-dependent tRNA methyltransferase (TrmFO)2012
- Author(s)
  R. Yamagami, K. Yamashita, H. Nishimasu, C. Tomikawa, A. Ochi, C. Iwashita, A. Hirata, R. Ishitani, O. Nureki, and H. Hori
- Organizer
  9th Extremophiles 2012
- Place of Presentation
  Spain
- Year and Date
  2012-09-09
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Expression and purification of yeast tRNA (Cm32/Gm34) methyltransferase (Trm7)2012
- Author(s)
  K. Yoshii, A. Hirata, and H. Hori
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 極小アーキアにおけるtRNAスプライシングエンドヌクレアーゼの構造機能解析2012
- Author(s)
  平田章、藤島皓介、山上龍太、河村卓哉、JF.Banfield、堀弘幸
- Organizer
  第25回日本アーキア研究会
- Place of Presentation
  兵庫
- Data Source
  KAKENHI-PROJECT-24770125
[Presentation] 極小アーキアにおけるtRNAスプライシングエンドヌクレアーゼの構造機能解析2012
- Author(s)
  平田章, 藤島皓介, 山上龍太, 河村卓哉, J. F. Banfield, 堀弘幸
- Organizer
  第25回日本アーキア研究会
- Place of Presentation
  兵庫
- Year and Date
  2012-07-18
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 世界最小クラスの生命体ARMANにおける４番目のタイプのtRNAスプライシングエンドヌクレアーゼのX線結晶構造解析2012
- Author(s)
  平田　章、藤島皓介、山上龍太、河村卓哉、JF. Banfield、堀　弘幸
- Organizer
  第１３回極限環境生物学会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24770125
[Presentation] サーマス・サーモフィラス由来tRNAメチル化酵素TrmFOの基質認識機構2012
- Author(s)
  山上龍太, 山下光輝, 西増弘志, 冨川千恵, 越智杏奈, 岩下智香子, 平田章, 石谷隆一郎, 濡木理, 堀弘幸
- Organizer
  第14回日本RNA学会年会
- Place of Presentation
  仙台
- Year and Date
  2012-07-16
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Structural and functional analyses of archaeal 2'-5' RNA ligase2012
- Author(s)
  T. Nagano, A. Hirata, Y. Ishimaru, T. Kanai, and H. Hori
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 酵母由来のtRNA (m2G10) methyltransferase (Trm11-Trm112)の基質認識機構の解明2012
- Author(s)
  西田裕, 岡田和樹, 平田章, 堀弘幸
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Negative control of Gm18, m5s2U54 and m1A58 modifications by pseudouridine55 modification in Thermus thermophilus tRNAs : the tRNA modification network in extreme thermophile2012
- Author(s)
  C. Tomikawa, K. Ishida, T. Kunibayashi, A. Ochi, T. Kanai, A. Hirata, C. Iwashita, and H. Hori
- Organizer
  24th tRNA workshop
- Place of Presentation
  Chilli
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 世界最小クラスの生命体ARMANにおける4番目のタイプのtRNAスプライシングエンドヌクレアーゼのX線結晶構造解析2012
- Author(s)
  平田章、藤島皓介、山上龍太、河村卓哉、JF.Banfield、堀弘幸
- Organizer
  第13回極限環境生物学会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24770125
[Presentation] Structural insight into the evolution and broad substrate specificity of the fourth type of tRNA splicing endonuclease2012
- Author(s)
  平田章、藤島皓介、山上龍太、河村卓哉、JF.Banfield、堀弘幸
- Organizer
  9th INTERNATIONAL CONGRESS ON EXTREMOPHILES 2012
- Place of Presentation
  スペイン
- Data Source
  KAKENHI-PROJECT-24770125
[Presentation] Research for substrate tRNA recognition mechanism of eubacterial tRNA (m1A58) methyltransferase (TrmI)2012
- Author(s)
  H. Takuma, M. Minoji, N. Ushio, C. Tomikawa, A. Hirata, A. Ochi and H. Hori
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Substrate transfer RNA recognition mechanism of tRNA (m5U54) methyltransferase (TrmFO) based on the biochemical and structural analysis.2012
- Author(s)
  R. Yamagami, K. Yamashita, H. Nishimasu, C. Iwashita, A. Hirata, O. Nureki, and H. Hori
- Organizer
  第2回モデル生物丸ごと一匹学会
- Place of Presentation
  SPring-8 (Harima)
- Year and Date
  2012-09-28
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Adaptation of Thermus thermophilus to environmental temperature via tRNA modification enzymes-modified nucleotides network in tRNA2012
- Author(s)
  C. Tomikawa, K. Ishida, T. Kunibayashi, A. Ochi, T. Kanai, A. Hirata, C. Iwashita, and H. Hori
- Organizer
  第2回モデル生物丸ごと一匹学会
- Place of Presentation
  SPring-8 (Harima)
- Year and Date
  2012-09-28
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Substrate tRNA recognition mechanism of eubacterial tRNA (m1A58) methyltransferase (TrmI)2012
- Author(s)
  H. Takuma, M. Minoji, N. Ushio, C. Tomikawa, A. Hirata, A. Ochi and H. Hori
- Organizer
  第2回モデル生物丸ごと一匹学会
- Place of Presentation
  SPring-8 (Harima)
- Year and Date
  2012-09-28
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Substrate tRNA recognition mechanism of eubacterial tRNA (m1A58) methyltransferase (TrmI)2011
- Author(s)
  Hiroyuki Takuma, Masayuki Minoji, Natsumi Ushio, Chie Tomikawa, Akira Hirata, Anna Ochi, Hiroyuki Hori
- Organizer
  The 38th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  札幌
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Structural and functional analyses of archaeal 2'-5' RNA ligase2011
- Author(s)
  T. Nagano, A. Hirata, Y. Ishimaru, T. Kanai, and H. Hori
- Organizer
  Thermophiles 2011
- Place of Presentation
  Big Sky, Montana, USA
- Year and Date
  2011-09-12
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Substrate tRNA recognition mechanism of FAD/folate-dependet tRNA m^5U54 methyltransferase TrmFO2011
- Author(s)
  R.Yamagami, K.Yamashita, H.Nishimasu, C.Iwashita, A.Hirata, O.Nureki, H.Hori
- Organizer
  16th Annual Meeting of RNA Society (RNA 20-11Kyoto)
- Place of Presentation
  京都
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 酵母由来のtRNA (m2G10) methyltransferase (Trm11-Trm112)の機能解析2011
- Author(s)
  西田裕, 岡田和樹, 平田章, 堀弘幸
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Regulation of tRNA modification network by pseudouridine 55 in Thermus thermophiles2011
- Author(s)
  C.Tomikawa, K.Ishida, T.Kunibayashi, A.Ochi, T.Kanai, A.Hirata, C.Iwashita, H.Hori
- Organizer
  16th Annual Meeting of RNA Society (RNA 2011Kyoto)
- Place of Presentation
  京都
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Thermus thermophilus tRNA (m1A58) methyltransferase [Trm1]の基質認識メカニズムの解明2011
- Author(s)
  詫間浩之, 美濃地真之, 牛尾なつみ, 冨川千恵, 平田章, 堀弘幸
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] サーマス・サーモフィラス由来葉酸依存性tRNA (m5U54)メチル化酵素の基質認識機構2011
- Author(s)
  山上龍太、山下光輝、西増弘志、岩下知香子、平田章、濡木理、堀弘幸
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Transfer RNA recognition mechanism of multi-site specific tRNA methyltransferase (Trm1)from Aquifex aeolicus2011
- Author(s)
  T.Awai, A.Ochi, Ihsanawati, A.Hirata, Y.Bessho, S.Yokoyama, H.Hori
- Organizer
  16th Annual Meeting of RNA Society (RNA 2011Kyoto)
- Place of Presentation
  京都
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Transfer RNA recognition mechanism of multi-site specific tRNA methyltransferase (Trm1) from Aquifex aeolicus2011
- Author(s)
  T. Awai, A. Ochi, Ihsanawati, A. Hirata, Y. Bessho, S. Yokoyama, and H. Hori
- Organizer
  16th Annual Meeting of RNA Society (RNA 2011Kyoto)
- Place of Presentation
  Kyoto
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Elucidation of substrate tRNA recognition mechanism by tRNA (m1A58) methyltransferase[TrmI] from Thermus thermophiles2011
- Author(s)
  H. Takuma, M. Minoji, N. Ushio, C. Tomikawa, A. Hirata, C. Iwashita, A. Ochi, and H. Hori
- Organizer
  第1回モデル生物丸ごと一匹学会・第10回高度好熱菌連携会議
- Place of Presentation
  理研・播磨(Spring-8)
- Year and Date
  2011-08-19
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Multisite specific tRNA methyltransferase Trm1 from a hyper-thermophilic eubacterium, Aquifex aeolicus2011
- Author(s)
  T. Awai, A. Ochi, Ihsanawati, T. Sengoku, S. Kimura, C. Tomikawa, T. Yokogawa, A. Hirata, Y. Bessho, T. Suzuki, S. Yokoyama and H. Hori
- Organizer
  Thermophiles 2011
- Place of Presentation
  Big Sky, Montana, USA
- Year and Date
  2011-09-12
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 古細菌における2'-5' RNA ligaseの構造機能解析2011
- Author(s)
  長野倫子, 平田章, 石丸雄基, 金井保, 堀弘幸
- Organizer
  RNAフロンティアミーティング
- Place of Presentation
  愛知県大府市
- Year and Date
  2011-08-30
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Thermus thermophilus tRNA (m1A58) methyltransferase[Trm1]の基質認識メカニズムの解明2011
- Author(s)
  詫間浩之、美濃地真之、牛尾なつみ、冨川千恵、平田章、堀弘幸
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] アーキアにおける2'-5' RNA ligaseの構造機能解析2011
- Author(s)
  長野倫子, 石丸雄基, 金井保, 平田章, 堀弘幸
- Organizer
  第12回極限環境生物学会年会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Recognition and cleavage of intron in precursor tRNA by the splicing endonuclease from Aperopyrum pernix, an aerobic hyper-thermophilic Crenarchaeon, thorough a novel RNA recognition site in Crenarchaea specific loop2011
- Author(s)
  A. Hirata, T. Kitajima, and H. Hori
- Organizer
  Thermophiles 2011
- Place of Presentation
  Big Sky, Montana, USA
- Year and Date
  2011-09-12
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Regulation of tRNA modification network by pseudouridine 55 in Thermus thermophiles2011
- Author(s)
  C. Tomikawa, K. Ishida, T. Kunibayashi, A. Ochi, T. Kanai, A. Hirata, C. Iwashita, and H. Hori
- Organizer
  16th Annual Meeting of RNA Society (RNA 2011Kyoto)
- Place of Presentation
  Kyoto
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] アーキアにおける2'-5' RNA ligaseの構造機能解析2011
- Author(s)
  長野倫子、石丸雄基、金井保、平田章、堀弘幸
- Organizer
  第12会極限環境生物学会年会
- Place of Presentation
  長崎
- Year and Date
  2011-11-23
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] The crystal structure analysis and establishment of activity mesurement system of Thermus thermophilus tRNA(Um34, Cm34) methyltransferase[YibK]2011
- Author(s)
  T.Matsugi, A.Hirata, H.Hori
- Organizer
  第1回モデル生物丸ごと一匹学会・第10回高度好熱菌連携会議
- Place of Presentation
  兵庫県佐用郡
- Year and Date
  2011-08-19
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 超好熱性古細菌Thermococcus kodakaraensis由来tRNA(m2G10/m22G10) methyltransferase (TK0981)の酵素学的性質の決定2011
- Author(s)
  田村俊浩, 平田章, 堀弘幸
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] アーキアRNAポリメラーゼのサブユニットDに見られる特異的ドメイン構造と機能の多様性と進化2011
- Author(s)
  平田章、堀弘幸、村上勝彦、Faith H.Lessner、Matthew Jenning、Eduardus, C.Duin、Daniel J.Lessner
- Organizer
  第12会極限環境生物学会年会
- Place of Presentation
  長崎
- Year and Date
  2011-11-23
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 酵母由来のtRNA (m2G10) methyltransferase (Trm11-Trm112)の機能解析2011
- Author(s)
  西田裕, 岡田和樹, 平田章, 堀弘幸
- Organizer
  RNAフロンティアミーティング
- Place of Presentation
  大府(愛知)
- Year and Date
  2011-08-30
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] A conserved Lys residue in Crenarchaea specific loop determines a broad substratespecificity of Crenarchaeal RNA splicing endonuclease2011
- Author(s)
  A. Hirata, T. Kitajima, and H. Hori
- Organizer
  16th Annual Meeting of RNA Society (RNA 2011Kyoto)
- Place of Presentation
  Kyoto
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 古細菌における2' - 5' RNA ligaseの構造機能解析2011
- Author(s)
  長野倫子, 平田章, 石丸雄基, 金井保, 堀弘幸
- Organizer
  RNAフロンティアミーティング
- Place of Presentation
  大府(愛知)
- Year and Date
  2011-08-30
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Substrate tRNA recognition mechanism of eubacterial tRNA (m1A58) methyltransferase (TrmI)2011
- Author(s)
  Hiroyuki Takuma, Masayuki Minoji, Natsumi Ushio, Chie Tomikawa, Akira Hirata, Anna Ochi, and Hiroyuki Hori
- Organizer
  The 38th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] The crystal structure analysis and establishment of activity mesurement system of Thermus thermophilus tRNA (Um34, Cm34) methyltransferase [YibK]2011
- Author(s)
  T. Matsugi, A. Hirata, and H. Hori
- Organizer
  第1回モデル生物丸ごと一匹学会・第10回高度好熱菌連携会議
- Place of Presentation
  理研・播磨(Spring-8)
- Year and Date
  2011-08-19
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Substrate tRNA recognition mechanism of FAD/folate-dependet tRNA m5U54 methyltransferase TrmFO2011
- Author(s)
  R. Yamagami, K. Yamashita, H. Nishimasu, C. Iwashita, A. Hirata, O. Nureki, and H. Hori
- Organizer
  16th Annual Meeting of RNA Society (RNA 2011Kyoto)
- Place of Presentation
  Kyoto
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] サーマス・サーモフィラス由来葉酸依存性tRNA(m5U54)メチル化酵素の基質認識機構2011
- Author(s)
  山上龍太, 山下光輝, 西増弘志, 岩下知香子, 平田章, 濡木理, 堀弘幸
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Elucidation of substrate tRNA recognition mechanism by tRNA (m^1A58)methyltransferase[TrmI]from Thermus thermophiles2011
- Author(s)
  H.Takuma, M.Minoji, N.Ushio, C.Tomikawa, A.Hirata, C.Iwashita, A.Ochi, H.Hori
- Organizer
  第1回モデル生物丸ごと一匹学会・第10回高度好熱菌連携会議
- Place of Presentation
  兵庫県佐用郡
- Year and Date
  2011-08-19
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] A conserved Lys residue in Crenarchaea specific loop determines a broad substratespecificity of Crenarchaeal RNA splicing endonuclease2011
- Author(s)
  A.Hirata, T.Kitajima, H.Hori
- Organizer
  16th Annual Meeting of RNA Society (RNA 2011Kyoto)
- Place of Presentation
  京都
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 酵母由来のtRNA (m2G10) methyltransferase (Trm11-Trm112)の機能解析2011
- Author(s)
  西田裕、岡田和樹、平田章、堀弘幸
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 酵母由来のtRNA (m^2G10) methyltransferase (Trm11-Trm112)の機能解析2011
- Author(s)
  芦田裕、岡田和樹、平田章、堀弘幸
- Organizer
  RNAフロンティアミーティング
- Place of Presentation
  愛知県大府市
- Year and Date
  2011-08-30
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Characterization of TrmJ[Transfer RNA(Cm32/Um32)Methyltransferase]Ortholog(TK1970)from a Hyperthermophilic Archaeon Thermococcus kodakarensis2010
- Author(s)
  平田章
- Organizer
  23^<rd> tRNA workshop
- Place of Presentation
  アベイロ会議場(ポルトガル)
- Year and Date
  2010-01-28
- Data Source
  KAKENHI-PROJECT-21770145
[Presentation] Substrate tRNA recognition mechanism of eubacterial tRNA (m1A58) methyltransferase (TrmI)
- Author(s)
  H. Takuma, M. Minoji, N. Ushio, C. Tomikawa, A. Hirata, A. Ochi and H. Hori
- Organizer
  第２回モデル生物丸ごと一匹学会
- Place of Presentation
  兵庫
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 超好熱性アーキアThermococcus kodakarensis RNA polymeraseのX線結晶構造
- Author(s)
  平田　章、Sung-Hoon Jun、金井　保、Thomas J. Santangelo、今中　忠行、村上　勝彦
- Organizer
  第27回日本Archaea研究会
- Place of Presentation
  立命館大学びわこ・くさつキャンパスエポック立命21エポックホール・滋賀県草津市
- Year and Date
  2014-07-24 – 2014-07-25
- Data Source
  KAKENHI-PUBLICLY-25118516
[Presentation] Functional analysis of yeast tRNA (m2G10) methyltransferase (Trm11-Trm112)
- Author(s)
  Y. Nishida, K. Okada, A. Hirata, and H. Hori
- Organizer
  第２回モデル生物丸ごと一匹学会
- Place of Presentation
  兵庫
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Eukaryotic tRNA (m2G10) methyltransferase (Trm11-Trm112) recognizes the whole structure of tRNA
- Author(s)
  Shiho Ohmori, Yu Nishida, Kazuki Okada, Akira Hirata, and Hiroyuki Hori
- Organizer
  第３回モデル生物丸ごと一匹学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Expression and purification of yeast tRNA (Cm32/Gm34) methyltransferase (Trm7)
- Author(s)
  K. Yoshii, A. Hirata, and H. Hori
- Organizer
  第３５回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 極小アーキアにおけるtRNAスプライシングエンドヌクレアーゼの構造機能解析
- Author(s)
  平田章，藤島皓介，山上龍太，河村卓哉，J. F. Banfield，堀　弘幸
- Organizer
  第２５回日本アーキア研究会
- Place of Presentation
  兵庫
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] サーマス・サーモフィラス由来tRNA メチル化酵素TrmFOの基質認識機構
- Author(s)
  山上龍太，山下光輝，西増弘志，冨川千恵，越智杏奈，岩下智香子，平田　章，石谷隆一郎，濡木　理，堀　弘幸
- Organizer
  第１４回日本RNA学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Structural insight into the evolution and broad substrate specificity of the fourth type of tRNA splicing endonuclease
- Author(s)
  A. Hirata, K. Fujishima, R. Yamagami, T. Kawamura, J. F. Banfiled, A. Kanai, and H. Hori
- Organizer
  9th Extremophiles 2012
- Place of Presentation
  スペイン
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Research for substrate tRNA recognition mechanism of eubacterial tRNA (m1A58) methyltransferase (TrmI)
- Author(s)
  H. Takuma, M. Minoji, N. Ushio, C. Tomikawa, A. Hirata, A. Ochi and H. Hori
- Organizer
  第３５回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Adaptation of Thermus thermophilus to environmental temperature via tRNA modification enzymes-modified nucleotides network in tRNA
- Author(s)
  C. Tomikawa, K. Ishida, T. Kunibayashi, A. Ochi, T. Kanai, A. Hirata, C. Iwashita, and H. Hori
- Organizer
  第２回モデル生物丸ごと一匹学会
- Place of Presentation
  兵庫
- Invited
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Structural and functional analyses of archaeal 2’-5’ RNA ligase
- Author(s)
  T. Nagano, A. Hirata, Y. Ishimaru, T. Kanai, and H. Hori
- Organizer
  第３５回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Thermococcus kodakarensis 由来tRNA メチル化酵素(Trm- m22G10)の構造機能解析
- Author(s)
  西山聖示、平田　章、田村俊浩、堀　弘幸
- Organizer
  2013年度極限環境生物学会年会
- Place of Presentation
  明治大学生田キャンパス
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Does D20 formation by eubacterial dihydrouridine synthase require the other modified nucleotides for its modification in tRNA?
- Author(s)
  楠葉浩晃、吉田剛士、岩崎絵梨、粟井貴子、平田　章、冨川千恵、山上龍太、堀　弘幸
- Organizer
  第３回モデル生物丸ごと一匹学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 真正細菌ジヒドロウリジン合成酵素はD20形成にtRNA上の他の修飾ヌクレオチドを必要とする
- Author(s)
  楠葉浩晃、吉田剛士、岩崎絵梨、粟井貴子、平田　章、冨川千恵、
- Organizer
  第１５回日本RNA学会年会
- Place of Presentation
  松山
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] ユーリアーキアRNAポリメラーゼのX線結晶構造から視えた真核生物RNAポリメラーゼII構造の進化
- Author(s)
  平田　章、Sung-Hoon Jun、金井　保、Thomas J. Santangelo、今中　忠行、村上　勝彦
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜・神奈川県横浜市
- Year and Date
  2014-11-25 – 2014-11-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-25118516
[Presentation] 酵母由来のtRNA (m2G10) methyltransferase (Trm11-Trm112)の基質認識機構の解明
- Author(s)
  西田　裕、岡田和樹、平田　章、堀　弘幸
- Organizer
  第３５回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Transfer RNA recognition mechanism of Thermus thermophilus folate/FAD-dependent tRNA methyltransferase (TrmFO)
- Author(s)
  R. Yamagami, K. Yamashita, H. Nishimasu, C. Tomikawa, A. Ochi, C. Iwashita, A. Hirata, R. Ishitani, O. Nureki, and H. Hori
- Organizer
  9th Extremophiles 2012
- Place of Presentation
  スペイン
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Substrate transfer RNA recognition mechanism of tRNA (m5U54) methyltransferase (TrmFO) based on the biochemical and structural analysis
- Author(s)
  R. Yamagami, K. Yamashita, H. Nishimasu, C. Iwashita, A. Hirata, O. Nureki, and H. Hori
- Organizer
  第２回モデル生物丸ごと一匹学会
- Place of Presentation
  兵庫
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] アーキアのRNA合成・編集加工を担う分子装置の構造基盤の解明
- Author(s)
  平田　章
- Organizer
  第15回極限環境生物学会年会
- Place of Presentation
  沖縄県今帰仁村コミュニティセンター・沖縄県今帰仁村
- Year and Date
  2014-11-01 – 2014-11-03
- Invited
- Data Source
  KAKENHI-PUBLICLY-25118516
[Presentation] Improvement of a protein purification method for nucleic acid-free in the case of recombinant tRNA (N2,N2-guanine)-dimethyltransferase (Trm1) from Aquifex aeolicus
- Author(s)
  S. Nishiyama, A. Hirata, T. Awai, and H. Hori
- Organizer
  第３５回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 超好熱性アーキア Thermococcus kodakarensis 由来 tRNATrp の
- Author(s)
  前田雄太、平田　章、長野倫子、土手智裕、鈴木健夫、金井　保、鈴木　勉、堀　弘幸
- Organizer
  2013年度極限環境生物学会年会
- Place of Presentation
  明治大学生田キャンパス
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 超好熱性アーキアThermococcus kodakarensis 2', 5'- RNA リガーゼの機能解析
- Author(s)
  平田　章、長野倫子、石丸雄基、金井　保、鈴木健夫、佐藤朝子、金井昭夫、鈴木　勉、堀　弘幸
- Organizer
  第１５回日本RNA学会年会
- Place of Presentation
  松山
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Negative control of Gm18, m5s2U54 and m1A58 modifications by pseudouridine55 modification in Thermus thermophilus tRNAs: the tRNA modification network in extreme thermophile
- Author(s)
  C. Tomikawa, K. Ishida, T. Kunibayashi, A. Ochi, T. Kanai, A. Hirata, C. Iwashita, and H. Hori
- Organizer
  24th tRNA workshop
- Place of Presentation
  チリ
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] Yeast tRNA (m2G10) methyltransferase (Trm11-Trm112)の基質認識機構の解明
- Author(s)
  大森志穂、西田　裕、岡田和樹、平田　章、堀　弘幸
- Organizer
  第１５回日本RNA学会年会
- Place of Presentation
  松山
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 高度好熱菌tRNA中のシュードウリジン55修飾は、温度変化への適応因子として機能する
- Author(s)
  冨川千恵，石田一雄，国林貴史，越智杏奈，金井　保，平田　章，岩下知香子，堀　弘幸
- Organizer
  第１４回日本RNA学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23350081
[Presentation] 葉酸依存性tRNA(m5U54)メチル化酵素TrmFOはどうやってtRNA中のU54を認識しているのか?
- Author(s)
  山上龍太, 山下光輝, 西増弘志, 冨川千恵, 越智杏奈, 岩下智香子, 平田　章, 石谷隆一郎, 濡木　理, 堀　弘幸
- Organizer
  第１５回日本RNA学会年会
- Place of Presentation
  松山
- Data Source
  KAKENHI-PROJECT-23350081

1. HORI Hiroyuki (20256960)

# of Collaborated Projects: 2 results

# of Collaborated Products: 96 results
2. SUZUKI Tsutomu (20292782)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. 横川隆志 (90242304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. ISHITANI Ryuichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HIRATA Akira 平田 章

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酵素タンパク質複合体形成による二機能性触媒反応メカニズムの構造基盤Principal Investigator

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Study on substrate tRNA recognition mechanisms of multiple subunit tRNA modification enzymes

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Elucidation of thermotolerant mechanism of the RNA essential for life activity under high-temperature environmentPrincipal Investigator

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Elucidation of dynamic-molecular recognition mechanism by the dimeric RNA maturation enzymesPrincipal Investigator

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アーキアの転写装置を利用した多段階転写反応の動的メカニズムの解明Principal Investigator

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アーキア（古細菌）RNAポリメラーゼにおける転写開始機構および転写調節機構の解明Principal Investigator

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Elucidation of mechanism of molecular dynamics recognition by RNA machineries involved in the thermostable RNA maturationPrincipal Investigator

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Structural basis and functional evolution of RNA maturation machinary

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RNA修飾酵素の基質認識機構の統一的パラダイムの構築Principal Investigator

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[Book] アーキア生物学2017

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[Journal Article] Required Elements in tRNA for Methylation by the Eukaryotic tRNA (Guanine- N2-) Methyltransferase (Trm11-Trm112 Complex)2022

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[Journal Article] Distinct Modified Nucleosides in tRNATrp from the Hyperthermophilic Archaeon Thermococcus kodakarensis and Requirement of tRNA m2G10/m22G10 Methyltransferase (Archaeal Trm11) for Survival at High Temperatures2019

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[Journal Article] Structure of tRNA methyltransferase complex of Trm7 and Trm734 reveals a novel binding interface for tRNA recognition2019

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[Journal Article] Identification of a radical SAM enzyme involved in the synthesis of archaeosine2019

HIRATA Akira 平田章