Matsushige Takeshi 松重武志

… Alternative Names

MATSUSHIGE Takeshi 松重武志

松重武志マツシゲタケシ

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Researcher Number	60528941
Other IDs
Affiliation (Current)	2025: 山口大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2015 – 2023: 山口大学, 医学部附属病院, 講師 2011: 山口大学, 医学部附属病院, 講師
Review Section/Research Field	Principal Investigator Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Pediatrics / Basic Section 58070:Lifelong developmental nursing-related / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords	Principal Investigator ウイルス / 感染症 / 急性弛緩性脊髄炎 / エンテロウイルスD68 / メタゲノム解析 / エンテロウイルス / ウィルス / アレルギー・ぜんそく / 気管支喘息 / 新型インフルエンザ … More / 脳神経疾患 / 病理 / サイトカイン / 急性弛緩性麻痺 … More Except Principal Investigator 免疫機能 / てんかん治療 / 難治てんかん / 乳児 / 医療的ケア児 / 腸内細菌叢 / IESS / 気管支喘息 / 腸内有機酸 / 経腸栄養製品 / ウエスト症候群 / エンテロウィルスD68 / 抗体療法 / サイトカイン / エンテロウイルスD68 / 生物学的製剤 / エンテロウイルス / 小児 / 腎瘢痕 / インターフェロンγ / 急性巣状細菌性腎炎 / IFN-γ / 高サイトカイン血症 / 上部尿路感染症 / 小児腎臓 / キノリン酸 / トリプトファン代謝 / プロテオミクス / バイオマーカー / 亜急性硬化性全脳炎 / インフルエンザウイルス / 気道上皮細胞 / エンテロウイルス68型 Less

医療的ケア児のてんかん発症早期の腸内細菌叢と免疫能の解析および追加治療の提案
- Principal Investigator
  
  星出まどか (梶本まどか)
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58070:Lifelong developmental nursing-related
- Research Institution
  Yamaguchi University
Elucidation of the Pathophysiology of Acute Flaccid Myelitis and Applications in Prevention and Treatment Using Human Nerve Tissue and Asthma Mouse ModelsPrincipal Investigator
- Principal Investigator
  
  Matsushige Takeshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Yamaguchi University
Effects on immune function and intestinal organic acids with long-term use of enteral nutrition products in medically managed children.
- Principal Investigator
  
  Hoshide Madoka
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58070:Lifelong developmental nursing-related
- Research Institution
  Yamaguchi University
エンテロウイルスD68感染による重症気管支喘息発作発症の解明および治療法の開発
- Principal Investigator
  
  安戸裕貴
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kyorin University
  Yamaguchi University
Establishing the diagnosis of acute focal bacterial nephritis in children
- Principal Investigator
  
  MIZUTANI Makoto
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Yamaguchi University
Pathophysiology and treatment in enterovirus D68-associated acute flaccid myelitisPrincipal Investigator
- Principal Investigator
  
  MATSUSHIGE Takeshi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Yamaguchi University
The investigation of pathophysiology and biomarkers in subacute sclerosing panencephalitis (SSPE)
- Principal Investigator
  
  HASEGAWA Shunji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Yamaguchi University
Bronchial asthma induces excessive inflammation and virus replication in pandemic influenza infection.Principal Investigator
- Principal Investigator
  
  MATSUSHIGE Takeshi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Yamaguchi University
エンテロウイルス68型感染による気管支喘息発作増悪の機序解明に関する研究
- Principal Investigator
  
  市山高志
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Yamaguchi University

All 2022 2021 2020 2019 2017 2016 2015

All Journal Article Presentation

[Journal Article] Histological characteristics of matrix metalloproteinase‐9 and tissue inhibitor of metalloproteinases‐1 in asthmatic murine model during A(H1N1)pdm09 infection2022
- Author(s)
  Kimura Sasagu、Yasudo Hiroki、Oga Atsunori、Fukano Reiji、Matsushige Takeshi、Hamano Hiroki、Hasegawa Hideki、Nakajima Noriko、Ainai Akira、Itoh Hiroshi、Shirabe Komei、Toda Shoichi、Atsuta Ryo、Hasegawa Shunji
- Journal Title
  
  Pathology International
  
  Volume: 72 Issue: 10 Pages: 506-518
- DOI
  10.1111/pin.13268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08301
[Journal Article] Enhanced airway hyperresponsiveness in asthmatic children and mice with A(H1N1)pdm09 infection.2021
- Author(s)
  Taira Ariyoshi, Junichiro Tezuka, Hiroki Yasudo, Yasufumi Sakata, Tamaki Nakamura 1, Takeshi Matsushige, Hideki Hasegawa, Noriko Nakajima, Akira Ainai, Atsunori Oga, Hiroshi Itoh, Komei Shirabe, Shoichi Toda, Ryo Atsuta, Shouichi Ohga, Shunji Hasegawa
- Journal Title
  
  Immunity, Inflammation and Disease
  
  Volume: 9 Issue: 2 Pages: 457-465
- DOI
  10.1002/iid3.406
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08301
[Journal Article] Efficacy of hypothermia therapy in patients with acute encephalopathy with biphasic seizures and late reduced diffusion2020
- Author(s)
  Hoshide Madoka, Yasudo Hiroki, Inoue Hirofumi, Matsushige Takeshi, et al
- Journal Title
  
  Brain Dev.
  
  Volume: 42 Pages: 515-522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K10937
[Journal Article] Elevated quinolinic acid levels in cerebrospinal fluid in subacute sclerosing panencephalitis2020
- Author(s)
  HiroHirofumi Inoue, Takeshi Matsushige, Takashi Ichiyama, Alato Okuno, Osamu Takikawa, Shozo Tomonaga, Banu Anlar, Deniz Yuksel, Yasushi Otsuka, Fumitaka Kohno, Madoka Hoshide, Shouichi Ohga, Shunji Hasegawa
- Journal Title
  
  J Neuroimmunol.
  
  Volume: 339 Pages: 577088-577088
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K10937
[Journal Article] Cytokine Profile in a Patient With Enterovirus D68-Associated Acute Flaccid Myelitis2019
- Author(s)
  Ippei Hidaka, Takeshi Matsushige, Hirofumi Inoue, Madoka Hoshide, Komei Shirabe, Shunji Hasegawa
- Journal Title
  
  Pediatr Neurol
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16266
[Journal Article] Distinctive inflammatory profile between acute focal bacterial nephritis and acute pyelonephritis in children.2017
- Author(s)
  Mizutani M, Hasegawa S, Matsushige T, Ohta N, Kittaka S, Hoshide M, Kusuda T, Takahashi K, Ichihara K, Ohga S.
- Journal Title
  
  Cytokine
  
  Volume: 99 Pages: 24-29
- DOI
  10.1016/j.cyto.2017.06.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10142
[Presentation] インフルエンザA(H1N1)pdm09感染喘息モデルマウスにおけるMMP-9とTIMP-1の病理的特2022
- Author(s)
  木村献, 松重武志, 安戸裕貴, 長谷川俊史
- Organizer
  第125回日本小児科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08301
[Presentation] Mechanisms of asthma(Enhanced airway hyperresponsiveness in a mouse model of asthma with A (H1N1) pdm09 infection)2020
- Author(s)
  Yasudo Hiroki, Ariyoshi Taira, Sakata Yasufumi, Nakamura Tamaki, Matsushige Takeshi, Hasegawa Hideki, Nakajima Noriko, Ainai Akira, Oga Atsunori, Itoh Hiroshi, Shirabe Komei, Toda Shoichi, Atsuta Ryo, Ohga Shouichi, Hasegawa Shunji
- Organizer
  JSA/WAO Joint Congress 2020
- Data Source
  KAKENHI-PROJECT-19K08301
[Presentation] 気管支喘息モデルマウスを用いたインフルエンザ感染時の肺病理組織の検討2017
- Author(s)
  松重武志、長谷川俊史、藤本洋輔、中村圭李、脇口宏之、大賀正一
- Organizer
  第120回日本小児科学会
- Place of Presentation
  グランドプリンスホテル新高輪（東京都・港区）
- Year and Date
  2017-04-14
- Data Source
  KAKENHI-PROJECT-15K19619
[Presentation] 気管支喘息マウスにおけるA(HlNl)pdm09感染による肺病理組織の変化2016
- Author(s)
  松重武志、長谷川俊史、藤本洋輔、中村圭李、脇口宏之、大賀正一、池本健三、小賀厚徳、伊藤浩史、長谷川秀樹、相内章、調恒明、戸田昌一、熱田了
- Organizer
  第48回日本小児感染症学会
- Place of Presentation
  岡山コンベンションセンター（岡山県・岡山市）
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-15K19619
[Presentation] 喘息マウスにおけるA(H1N1)pdm09感染によるBAL中サイトカイン動態の検討2016
- Author(s)
  藤本洋輔、長谷川俊史、松重武志、脇口宏之、長谷川秀樹、相内章、調恒明、戸田昌一、熱田了、大賀正一
- Organizer
  日本小児科学会
- Place of Presentation
  ロイトン札幌（札幌市中央区）
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-15K19619
[Presentation] 亜急性硬化性全脳炎におけるキヌレニン経路活性化の検討2015
- Author(s)
  松重武志, 井上裕文, 梶本まどか, 岡桃子, 長谷川俊史, 大森啓充, 奥野海良人, 滝川修, 大賀正一
- Organizer
  第57回日本小児神経学会
- Place of Presentation
  帝国ホテル大阪 (大阪府大阪市)
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-15K09654

1. HASEGAWA Shunji (90314806)

# of Collaborated Projects: 5 results

# of Collaborated Products: 9 results
2. Hoshide Madoka (30610878)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 市山高志 (20263767)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 大賀正一 (60233053)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. 脇口宏之 (00716590)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. SHIRABE Komei

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. MIZUTANI Makoto (10593303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 平野玲史 (20575196)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 安戸裕貴 (70422285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. 井上裕文 (70650604)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 東良紘 (00792219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. DOI Kazuteru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. CUI Dan

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. IKEDA Eiji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. FUJIMOTO Yousuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
16. WAKABAYASHI Midori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. NAKAMURA Tamaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. HASEGAWA Hideki

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
19. AINAI Akira

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
20. IKEMOTO Kenzo

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. OGA Atsunori

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. ITOH Hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. TODA Shoichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
24. ATSUTA Ryo

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
25. 梶本まどか

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Matsushige Takeshi 松重 武志

MATSUSHIGE Takeshi 松重 武志

松重 武志 マツシゲ タケシ

Research Projects

Research Products

Co-Researchers

医療的ケア児のてんかん発症早期の腸内細菌叢と免疫能の解析および追加治療の提案

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the Pathophysiology of Acute Flaccid Myelitis and Applications in Prevention and Treatment Using Human Nerve Tissue and Asthma Mouse ModelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effects on immune function and intestinal organic acids with long-term use of enteral nutrition products in medically managed children.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

エンテロウイルスD68感染による重症気管支喘息発作発症の解明および治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishing the diagnosis of acute focal bacterial nephritis in children

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathophysiology and treatment in enterovirus D68-associated acute flaccid myelitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The investigation of pathophysiology and biomarkers in subacute sclerosing panencephalitis (SSPE)

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Bronchial asthma induces excessive inflammation and virus replication in pandemic influenza infection.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

エンテロウイルス68型感染による気管支喘息発作増悪の機序解明に関する研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Histological characteristics of matrix metalloproteinase‐9 and tissue inhibitor of metalloproteinases‐1 in asthmatic murine model during A(H1N1)pdm09 infection2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enhanced airway hyperresponsiveness in asthmatic children and mice with A(H1N1)pdm09 infection.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Efficacy of hypothermia therapy in patients with acute encephalopathy with biphasic seizures and late reduced diffusion2020

Author(s)

Journal Title

Data Source

[Journal Article] Elevated quinolinic acid levels in cerebrospinal fluid in subacute sclerosing panencephalitis2020

Author(s)

Journal Title

Data Source

[Journal Article] Cytokine Profile in a Patient With Enterovirus D68-Associated Acute Flaccid Myelitis2019

Author(s)

Matsushige Takeshi 松重武志

MATSUSHIGE Takeshi 松重武志

松重武志マツシゲタケシ