Hirosawa Mitsuko 廣澤瑞子

… Alternative Names

HIROSAWA Mitsuko 廣澤瑞子

高森瑞子タカモリミツコ

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Researcher Number	60533982
Other IDs
Affiliation (based on the past Project Information) *help	2015 – 2017: 東京大学, 大学院農学生命科学研究科(農学部), 助教 2014 – 2016: 東京大学, 農学生命科学研究科, 助教 2011: 東京大学, 大学院・農学生命科学研究科, 特任准教授 2010: 東京大学, 大学院・農学生命科学研究科, 特任助教
Review Section/Research Field	Principal Investigator Applied molecular and cellular biology / Genome biology Except Principal Investigator Integrative animal science
Keywords	Principal Investigator ES細胞 / セレノプロテイン / タンパク質複合体 / エピジェネティクス / DNAメチル化 / ヒストン修飾 / SelH / セレン / エピジェネティックス / エピゲノム … More Except Principal Investigator … More ゲノムワイド / グリコシル化 / ゲノムダメージ / Nアセチルグルコサミン（GlcNAc） / 進化 / 胚性幹細胞 / 栄養膜幹細胞 / グルコース感受性 / ゲノム修復 / H2A-アセチルグルコサミン（GlcNAc）修飾 / ヒストン修飾 / エピジェネティクス Less

Identification of the selenoprotein complex functioning epigenetic regulationPrincipal Investigator
- Principal Investigator
  
  Hirosawa Mitsuko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  The University of Tokyo
Epigenetics of trophoblast and embryonic stem cells by a novel histone-glycosylation
- Principal Investigator
  
  Shiota Kunio
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Integrative animal science
- Research Institution
  Waseda University
  The University of Tokyo
Epigenetic regulation by selenoproteinsPrincipal Investigator
- Principal Investigator
  
  HIROSAWA Mitsuko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Genome biology
- Research Institution
  The University of Tokyo

All 2018 2017 2016 2015 2012 2011 Other

All Journal Article Presentation Book Patent

[Book] 2017年度版現代用語の基礎知識2017
- Author(s)
  廣澤瑞子
- Total Pages
  1363
- Publisher
  自由国民社
- Data Source
  KAKENHI-PROJECT-15K07836
[Book] 現代用語の基礎知識20182017
- Author(s)
  廣澤瑞子共著　科学技術・化学,　p687-692担当
- Total Pages
  1384
- Publisher
  自由国民社
- ISBN
  4426101360
- Data Source
  KAKENHI-PROJECT-15K07836
[Book] 眠れなくなるほど面白い　図解　生物の話2017
- Author(s)
  廣澤瑞子
- Total Pages
  128
- Publisher
  日本文芸社
- ISBN
  4537215399
- Data Source
  KAKENHI-PROJECT-15K07836
[Book] 栄養とエピジェネティクス2012
- Author(s)
  廣澤瑞子、八木慎太郎、塩田邦郎、健昂社
- Data Source
  KAKENHI-PROJECT-22651070
[Journal Article] H2A O-GlcNAcylation at serine 40 functions genomic protection in association with acetylated H2AZ or γH2AX.2017
- Author(s)
  Hayakawa K, Hirosawa M, Tani R, Yoneda C, Tanaka S, Shiota K.
- Journal Title
  
  Epigenetics Chromatin.
  
  Volume: 10(1) Issue: 1 Pages: 51-51
- DOI
  10.1186/s13072-017-0157-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07836
[Journal Article] Novel O-GlcNAcylation on Ser40 of canonical H2A isoforms specific to viviparity.2016
- Author(s)
  Hirosawa M, Hayakawa K, Yoneda C, Arai D, Shiota H, Suzuki T, Tanaka S, Dohmae N, Shiota K.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1
- DOI
  10.1038/srep31785
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26252052, KAKENHI-PROJECT-26850230, KAKENHI-PROJECT-15K07836
[Journal Article] An epigenetic regulatory element of the Nodal gene in the mouse and human genomes.2015
- Author(s)
  Arai D, Hayakawa K, Ohgane J, Hirosawa M, Nakao Y, Tanaka S, Shiota K.
- Journal Title
  
  Mech Dev.
  
  Volume: 136 Pages: 143-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26252052
[Journal Article] An epigenetic regulatory element of the Nodal gene in the mouse and human genomes2015
- Author(s)
  Daisuke Arai, Koji Hayakawa, Jun Ohgane, Mitsuko Hirosawa, Yoichi Nakao, Satoshi Tanaka, Kunio Shiota
- Journal Title
  
  Mechanisms of Development
  
  Volume: 136 Pages: 143-154
- DOI
  10.1016/j.mod.2014.12.003
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25850219, KAKENHI-PROJECT-26850230, KAKENHI-PROJECT-15K07836, KAKENHI-PROJECT-25450472, KAKENHI-PROJECT-25303008, KAKENHI-PROJECT-15H01749
[Journal Article] Putative Epimutagens in Maternal Peripheral and Cord Blood Samples Identified Using Human Induced Pluripotent Stem Cells.2015
- Author(s)
  Arai Y, Hayakawa K, Arai D, Ito R, Iwasaki Y, Saito K, Akutsu K, Takatori S, Ishii R, Hayashi R, Izumi S, Sugino N, Kondo F, Horie M, Nakazawa H, Makino T, Hirosawa M, Shiota K, Ohgane J.
- Journal Title
  
  Biomed Res Int.
  
  Volume: 2015 Pages: 1-13
- DOI
  10.1155/2015/876047
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07836, KAKENHI-PROJECT-25450472, KAKENHI-PROJECT-15H01749, KAKENHI-PROJECT-26252052
[Journal Article] DNA methylation profile : a composer-, conductor-, and player-orchestrated mammalian genome consisting of genes and transposable genetic elements2012
- Author(s)
  Yagi S, Hirosawa M and Shiota K
- Journal Title
  
  J. Reproid. Dev
  
  Volume: (in press)
- NAID
  10030820772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651070
[Journal Article] Analyses of fruit flies that do not express selenoproteins or express the mouse selenoprotein, methionine sulfoxide reductase B1, reveal a role of selenoproteins in stress resistance2011
- Author(s)
  Shchedrina VA, Kabil H, Vorbruggen G, Lee BC, Turanov AA, Hirosawa-Takamori M, Kim HY, Harshman LG, Hatfield DL and Gladyshev VN
- Journal Title
  
  J Biol Chem
  
  Volume: 286(34) Issue: 34 Pages: 29449-29461
- DOI
  10.1074/jbc.m111.257600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651070
[Patent] 糖感知エピゲノムバイオマーカー2016
- Inventor(s)
  塩田邦郎、廣澤瑞子、早川晃司
- Industrial Property Rights Holder
  塩田邦郎、廣澤瑞子、早川晃司
- Industrial Property Rights Type
  特許
- Filing Date
  2016-09-08
- Overseas
- Data Source
  KAKENHI-PROJECT-26252052
[Patent] グルコース感受性細胞の保護剤2016
- Inventor(s)
  塩田邦郎、早川晃司、廣澤ー高森瑞子、藤井遼介、伊藤幸成
- Industrial Property Rights Holder
  塩田邦郎、早川晃司、廣澤ー高森瑞子、藤井遼介、伊藤幸成
- Industrial Property Rights Type
  特許
- Filing Date
  2016-04-01
- Overseas
- Data Source
  KAKENHI-PROJECT-26252052
[Patent] グルコース感受性細胞の保護剤2015
- Inventor(s)
  塩田邦郎・早川晃司・廣澤瑞子・藤井遼介・伊藤幸成
- Industrial Property Rights Holder
  塩田邦郎・早川晃司・廣澤瑞子・藤井遼介・伊藤幸成
- Industrial Property Rights Type
  特許
- Filing Date
  2015-04-03
- Data Source
  KAKENHI-PROJECT-26252052
[Patent] 糖感知エピゲノムバイオマーカー2015
- Inventor(s)
  塩田邦郎・廣澤瑞子・早川晃司
- Industrial Property Rights Holder
  塩田邦郎・廣澤瑞子・早川晃司
- Industrial Property Rights Type
  特許
- Filing Date
  2015-09-09
- Data Source
  KAKENHI-PROJECT-26252052
[Presentation] マウスES細胞におけるセレノプロテインHのエピジェネテッィク作用2018
- Author(s)
  廣澤瑞子
- Organizer
  日本薬学会第１３８年会、金沢
- Invited
- Data Source
  KAKENHI-PROJECT-15K07836
[Presentation] ヒストンH4Thr71における新規O-GlcNAc修飾2017
- Author(s)
  奈良大輔、廣澤瑞子、西谷健汰、早川晃司、塩田邦郎、田中智
- Organizer
  第40回日本分子生物学会年会、神戸
- Data Source
  KAKENHI-PROJECT-15K07836
[Presentation] Novel O-GlcNAcylation on L1 region of canonical H2A specific to isoforms2017
- Author(s)
  Hirosawa M, Hayakawa K, Yoneda C, Arai D, Shiota H, Suzuki T, Tanaka S, Dohmae N and Shiota K
- Organizer
  第17回東京大学生命科学シンポジウム,　東京
- Data Source
  KAKENHI-PROJECT-15K07836
[Presentation] マウスES細胞におけるセレノプロテインHのエピジェネテッィク作用2017
- Author(s)
  廣澤瑞子、田部井靖亨、早川晃司、奈良大輔、塩田邦郎、田中智
- Organizer
  第11回　エピジェネティック研究会, 東京
- Data Source
  KAKENHI-PROJECT-15K07836
[Presentation] ヒストンH2A O-GlcNAc修飾による哺乳類特有DNA修復機構2017
- Author(s)
  早川晃司、廣澤瑞子、谷瑠依子、米田智佳子、田中智、塩田邦郎
- Organizer
  第11回　エピジェネティック研究会, 東京
- Data Source
  KAKENHI-PROJECT-15K07836
[Presentation] マウスES細胞におけるセレノプロテインHのエピジェネテッィク作用2017
- Author(s)
  廣澤瑞子、田部井靖亨、早川晃司、奈良大輔、塩田邦郎、田中智
- Organizer
  第40回日本分子生物学会年会、神戸
- Data Source
  KAKENHI-PROJECT-15K07836
[Presentation] ヒストンH2A O-GlcNAc修飾による哺乳類特有DNA修復機構2016
- Author(s)
  早川晃司・廣澤瑞子・谷瑠依子・米田智佳子・田中智・塩田邦郎
- Organizer
  第３９回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26252052
[Presentation] ヒストンH2AのL1領域におけるアイソフォーム特異的な新規O-GlcNAc修飾2016
- Author(s)
  廣澤瑞子・早川晃司・米田智佳子・新井大祐・塩田仁志・鈴木健裕・田中智・堂前直・塩田邦郎
- Organizer
  第３９回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川・横浜）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K07836
[Presentation] 糖による新たなヒストン修飾を発見2016
- Author(s)
  廣澤瑞子
- Organizer
  平成２８年度農学系研究科研究交流会
- Place of Presentation
  東京大学農学部弥生講堂アネックス（東京・文京区）
- Data Source
  KAKENHI-PROJECT-15K07836
[Presentation] ヒストンH2AのL1領域におけるアイソフォーム特異的な新規O-GlcNAc修飾2016
- Author(s)
  廣澤瑞子・早川晃司・米田智佳子・新井大祐・塩田仁志・鈴木健裕・田中智・堂前直・塩田邦郎
- Organizer
  第３９回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26252052
[Presentation] 糖による新たなヒストン修飾を発見2016
- Author(s)
  廣澤瑞子
- Organizer
  平成２８年度農学系研究科研究交流会
- Place of Presentation
  東京大学農学部弥生講堂アネックス（東京）
- Year and Date
  2016-11-14
- Data Source
  KAKENHI-PROJECT-26252052
[Presentation] Selenoprotein H contributes to epigenetic status in ES cells2012
- Author(s)
  Tabei Y, Hirosawa M, Tanaka S, Yagi S and Kunio Shiota
- Organizer
  2012 Keystone Symposia" The Life of a Stem Cell : From Birth to Death"
- Place of Presentation
  Olympic Valley, CA. U. S. A
- Year and Date
  2012-03-15
- Data Source
  KAKENHI-PROJECT-22651070
[Presentation] エピジェネティック因子としてのSelenoprotein Hの機能2012
- Author(s)
  田部井靖享、廣澤瑞子、田中智、八木慎太郎、塩田邦郎
- Organizer
  第6回エピジェネティクス研究会年会
- Place of Presentation
  学術総合センター(東京)
- Year and Date
  2012-05-14
- Data Source
  KAKENHI-PROJECT-22651070
[Presentation] The influence of glucose concentration on the pluripotency of mouse embryonic stem cells
- Author(s)
  Chikako Yoneda, Koji Hayakawa, Mitsuko Hirosawa, Satoshi Tanaka, Kunio Shiota
- Organizer
  The 2014 ASCB/IFCB meeting
- Place of Presentation
  フィラデルフィア、アメリカ
- Year and Date
  2014-12-06 – 2014-12-10
- Data Source
  KAKENHI-PROJECT-26252052
[Presentation] O-linked N-acetylglucosamine transderase accumulates at Mgea5, β-N-acetylglucosaminidase gene loci in mouse trophoblast stem cell
- Author(s)
  Kenta Nishitani, Koji Hayakawa, Mitusko HIrosawa, Satoshi Tanaka, Kunio Shiota
- Organizer
  The 2014 ASCB/IFCB meeting
- Place of Presentation
  フィラデルフィア、アメリカ
- Year and Date
  2014-12-06 – 2014-12-10
- Data Source
  KAKENHI-PROJECT-26252052

1. Shiota Kunio (80196352)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. 新井大祐 (20624951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. 早川晃司 (50636800)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results

Hirosawa Mitsuko 廣澤 瑞子

HIROSAWA Mitsuko 廣澤 瑞子

高森 瑞子 タカモリ ミツコ

Research Projects

Research Products

Co-Researchers

Identification of the selenoprotein complex functioning epigenetic regulationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Epigenetics of trophoblast and embryonic stem cells by a novel histone-glycosylation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Epigenetic regulation by selenoproteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 2017年度版 現代用語の基礎知識2017

Author(s)

Total Pages

Publisher

Data Source

[Book] 現代用語の基礎知識20182017

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 眠れなくなるほど面白い 図解 生物の話2017

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 栄養とエピジェネティクス2012

Author(s)

Data Source

[Journal Article] H2A O-GlcNAcylation at serine 40 functions genomic protection in association with acetylated H2AZ or γH2AX.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel O-GlcNAcylation on Ser40 of canonical H2A isoforms specific to viviparity.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An epigenetic regulatory element of the Nodal gene in the mouse and human genomes.2015

Author(s)

Journal Title

Data Source

[Journal Article] An epigenetic regulatory element of the Nodal gene in the mouse and human genomes2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Putative Epimutagens in Maternal Peripheral and Cord Blood Samples Identified Using Human Induced Pluripotent Stem Cells.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DNA methylation profile : a composer-, conductor-, and player-orchestrated mammalian genome consisting of genes and transposable genetic elements2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Analyses of fruit flies that do not express selenoproteins or express the mouse selenoprotein, methionine sulfoxide reductase B1, reveal a role of selenoproteins in stress resistance2011

Author(s)

Journal Title

DOI

Data Source

[Patent] 糖感知エピゲノムバイオマーカー2016

Inventor(s)

Hirosawa Mitsuko 廣澤瑞子

HIROSAWA Mitsuko 廣澤瑞子

高森瑞子タカモリミツコ

[Book] 2017年度版現代用語の基礎知識2017

[Book] 眠れなくなるほど面白い　図解　生物の話2017