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sekine hidekazu  関根 秀一

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Sekine Hidekazu  関根 秀一

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Researcher Number 60541737
Other IDs
Affiliation (Current) 2025: 東京女子医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help 2022 – 2024: 東京女子医科大学, 医学部, 准教授
2019 – 2021: 東京女子医科大学, 医学部, 講師
2014 – 2016: 東京女子医科大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 90110:Biomedical engineering-related / Biomedical engineering/Biomaterial science and engineering
Except Principal Investigator
Basic Section 90110:Biomedical engineering-related
Keywords
Principal Investigator
細胞シート / 血管床 / 灌流培養 / バイオリアクター / 再生医療 / 心筋再生 / 組織工学 / 心筋球 / 3次元組織 / リンパ管 … More / 脂肪由来間質細胞 / リンパ管切除モデル / 共培養 / リンパ管内皮細胞 / リンパ管再生 / 毛細血管 / 心筋カフ / 血管網導入 / 段階的積層化 / 立体組織 / 生体内チャンバー / 心筋組織 / 心不全 / 循環補助 / 血管新生 / 血管網付与 / 心筋細胞 / ヒト組織モデル / 組織モデル … More
Except Principal Investigator
血管内皮網 / 膵島β細胞 / 細胞シート / 組織工学 / 灌流培養 / 立体的組織 / 立体組織 / 膵臓再生 / 血管床 / 温度変化 / 血管網 / 人工代用尿管 / 心筋細胞 / 尿管蠕動運動 / 再生医療 / 尿管再生 / 担癌モデル動物 / 腫瘍モデル / がん組織工学 / 過重力 / がん細胞 / 細胞パッチ Less
  • Research Projects

    (8 results)
  • Research Products

    (33 results)
  • Co-Researchers

    (13 People)
  •  Next generation of regenerative therapies for the treatment of severe heart failure: the creation of a biological heart-assist devicePrincipal Investigator

    • Principal Investigator
      関根 秀一
    • Project Period (FY)
      2024 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Tokyo Women's Medical University
  •  Development of bio-pulsating ureter using self-organizing collagen tube

    • Principal Investigator
      佐々木 裕
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Jikei University School of Medicine
  •  低温灌流培養と血管網付膵島β細胞シートを用いた立体的膵島β細胞組織構築法の確立

    • Principal Investigator
      清水 達也
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Tokyo Women's Medical University
  •  Establishment of a pancreas-like tissue construction method using pancreatic islet beta cell sheets with vascular endothelial network

    • Principal Investigator
      Homma Jun
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Tokyo Women's Medical University
  •  Development of artificial lymphatic tissue that enables homeostasis of microenvironmentPrincipal Investigator

    • Principal Investigator
      Sekine Hidekazu
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Tokyo Women's Medical University
  •  Creation of functional heart tissues with perfusable vasculature using in vivo prevascularization techniquesPrincipal Investigator

    • Principal Investigator
      Sekine Hidekazu
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Tokyo Women's Medical University
  •  Development of innovative human tumor models using cell patch method for high-speed three-dimensional organization

    • Principal Investigator
      Nakayama Masamichi
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Tokyo Women's Medical University
  •  In vitro fabrication of Human heart tissue model with perfusable blood vesselsPrincipal Investigator

    • Principal Investigator
      Sekine Hidekazu
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Tokyo Women's Medical University

All 2024 2023 2022 2021 2020 2019 2017 2016 2015

All Journal Article Presentation Book Patent

  • [Book] Methods in Molecular Biology2022

    • Author(s)
      Hidekazu Sekine, Teruo Okano
    • Total Pages
      309
    • Publisher
      Springer Nature
    • ISBN
      9781071622605
    • Data Source
      KAKENHI-PROJECT-19H04453
  • [Book] Cell Sheets for Cardiac Tissue Engineering2020

    • Author(s)
      Hidekazu Sekine, Jun Homma, Tatsuya Shimizu
    • Total Pages
      19
    • Publisher
      Springer International Publishing
    • ISBN
      9783030442101
    • Data Source
      KAKENHI-PROJECT-19H04453
  • [Book] Tissue Engineering and Regeneration. Organ Tissue Engineering2020

    • Author(s)
      Hidekazu Sekine, Jun Homma, Tatsuya Shimizu
    • Publisher
      Springer
    • ISBN
    • Data Source
      KAKENHI-PROJECT-19H04453
  • [Journal Article] Tricultured Cell Sheets Develop into Functional Pancreatic Islet Tissue with a Vascular Network2023

    • Author(s)
      Homma Jun、Sekine Hidekazu、Shimizu Tatsuya
    • Journal Title

      Tissue Engineering Part A

      Volume: 29 Issue: 7-8 Pages: 211-224

    • DOI

      10.1089/ten.tea.2022.0167

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K12654, KAKENHI-PROJECT-23K25198
  • [Journal Article] The bioengineering of perfusable endocrine tissue with anastomosable blood vessels2023

    • Author(s)
      Yago Hiroki、Homma Jun、Sekine Hidekazu、Higashi Yuhei、Sakurai Hiroyuki、Shimizu Tatsuya
    • Journal Title

      Biofabrication

      Volume: 15 Issue: 4 Pages: 045010-045010

    • DOI

      10.1088/1758-5090/ace9fc

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K12654, KAKENHI-PROJECT-23K25198
  • [Journal Article] uccessful reconstruction of the rat ureter by a syngeneic collagen tube with a cardiomyocyte sheet2023

    • Author(s)
      Shutaro Yamamoto, Kenji Matsui, Yoshitaka Kinoshita, Hiroshi Sasaki, Hidekazu Sekine, Yatsumu Saito, Yasuhide Nakayama, Haruki Kume, Takahiro Kimura, Takashi Yokoo, Eiji Kobayashi
    • Journal Title

      Regenerative Therapy

      Volume: 24 Pages: 561-567

    • DOI

      10.1016/j.reth.2023.10.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K25182
  • [Journal Article] Networked lymphatic endothelial cells in a transplanted cell sheet contribute to form functional lymphatic vessels2022

    • Author(s)
      Nagahara Ayumi Inoue、Homma Jun、Ryu Bikei、Sekine Hidekazu、Higashi Yuhei、Shimizu Tatsuya、Kawamata Takakazu
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 21698-21698

    • DOI

      10.1038/s41598-022-26041-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K17978, KAKENHI-PROJECT-20K21910
  • [Journal Article] Bioartificial pulsatile cuffs fabricated from human induced pluripotent stem cell-derived cardiomyocytes using a pre-vascularization technique2022

    • Author(s)
      Yuki Endo, Jun Homma, Hidekazu Sekine, Katsuhisa Matsuura, Tatsuya Shimizu, Hiroshi Niinami
    • Journal Title

      npj Regenerative Medicine

      Volume: 7 Issue: 1 Pages: 1-10

    • DOI

      10.1038/s41536-022-00218-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H04453
  • [Journal Article] Perfusable vascular tree like construction in 3D cell-dense tissues using artificial vascular bed2022

    • Author(s)
      Yusuke Tobe, Jun Homma, Katsuhisa Skaguchi, Hidekazu Sekine, Kiyotaka Iwasaki, Tatsuya Shimizu
    • Journal Title

      Microvascular research

      Volume: 141 Pages: 104321-104321

    • DOI

      10.1016/j.mvr.2022.104321

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H04453, KAKENHI-PROJECT-21K20415
  • [Journal Article] Capillary Networks for Bio-Artificial Three-Dimensional Tissues Fabricated Using Cell Sheet Based Tissue Engineering2021

    • Author(s)
      Hidekazu Sekine, Teruo Okano
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 1 Pages: 1-12

    • DOI

      10.3390/ijms22010092

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H04453
  • [Journal Article] Engineering of functional cardiac tubes by stepwise transplantation of cardiac cell sheets onto intestinal mesentery2020

    • Author(s)
      Noriyasu Masuda, Hidekazu sekine, Hiroshi Niinami, Tatsuya Shimizu
    • Journal Title

      Heart and Vessels

      Volume: - Issue: 6 Pages: 859-867

    • DOI

      10.1007/s00380-019-01550-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H04453
  • [Journal Article] Generation of a large-scale vascular bed for the in vitro creation of three-dimensional cardiac tissue2019

    • Author(s)
      Akitoshi Inui, Hidekazu Sekine, Kazunori Sano, Izumi Dobashi, Azumi Yoshida, Katsuhisa Matsuura, Eiji Kobayashi, Minoru Ono, Tatsuya Shimizu
    • Journal Title

      Regenerative Therapy

      Volume: 11 Pages: 316-323

    • DOI

      10.1016/j.reth.2019.10.001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H04453
  • [Patent] 人工血管床、人工三次元生体組織及び血管網を備えた人工三次元生体組織の作製方法2021

    • Inventor(s)
      戸部友輔、本間順、関根秀一、坂口勝久、清水達也
    • Industrial Property Rights Holder
      戸部友輔、本間順、関根秀一、坂口勝久、清水達也
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2021-182725
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-19H04453
  • [Presentation] 細胞シートによるハイブリッドバイオチューブによる尿管再建法の検討2024

    • Author(s)
      山本修太郎、松井 賢治、木下 善隆、佐々木 裕、関根 秀一、齋藤 弥積、中山 泰秀、横尾 隆、小林 英司
    • Organizer
      第23回再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-23K25182
  • [Presentation] 32℃環境灌流培養における栄養および機能血管を有する内分泌組織構築と移植2023

    • Author(s)
      矢後博基, 本間順, 関根秀一, 東祐平, 清水達也
    • Organizer
      第22回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-23K25198
  • [Presentation] 膵島様組織構築のための血管内皮共培養膵β細胞シートにおける内皮細胞の役割2023

    • Author(s)
      本間順, 矢後博基, 関根秀一, 清水達也
    • Organizer
      第22回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-23K25198
  • [Presentation] 32℃環境灌流培養における栄養および機能血管を有する内分泌組織構築と移植2023

    • Author(s)
      矢後博基, 本間 順, 関根 秀一, 東祐平, 清水 達也
    • Organizer
      第22回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-21K12654
  • [Presentation] 間欠的加圧による血管内皮共培養系での血管網付与効果の検討2023

    • Author(s)
      勝浦美沙子, 本間 順, 東 祐平, 関根秀一, 清水達也
    • Organizer
      第22回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-23K25198
  • [Presentation] 高細胞密度の立体組織への灌流可能な栄養血管網導入を実現する灌流培養技術の開発2023

    • Author(s)
      戸部友輔, 本間順, 関根秀一, 坂口勝久, 岩崎清隆, 清水達也
    • Organizer
      第22回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-23K25198
  • [Presentation] 間欠的加圧培養の細胞への影響検証と血管網豊富な移植組織の構築2023

    • Author(s)
      勝浦美沙子、本間順、東祐平、高木亮、関根秀一、永田智、清水達也
    • Organizer
      第23回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-23K25198
  • [Presentation] 膵島様組織構築のための血管内皮共培養膵β細胞シートにおける内皮細胞の役割2023

    • Author(s)
      本間 順,矢後博基, 関根 秀一, 清水 達也
    • Organizer
      第22回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-21K12654
  • [Presentation] 血液循環補助可能な人工的カフ型ヒト心筋組織の作製2022

    • Author(s)
      遠藤祐輝, 本間順, 関根秀一, 松浦勝久, 清水達也, 新浪博士
    • Organizer
      第21回日本再生医療学会
    • Data Source
      KAKENHI-PROJECT-19H04453
  • [Presentation] ティッシュエンジニアリングによる血管導入三次元組織の再生2022

    • Author(s)
      関根秀一
    • Organizer
      第122回日本外科学会定期学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K21910
  • [Presentation] リンパ管内皮ネットワークシート移植によるリンパ管網構築法に関する基礎検討2022

    • Author(s)
      井上 歩, 関根 秀一, 劉 美憬, 本間 順, 清水 達也, 川俣 貴一
    • Organizer
      第21回日本再生医療学会
    • Data Source
      KAKENHI-PROJECT-20K21910
  • [Presentation] 生体外における灌流可能な血管網の高細胞密度の立体組織への付与技術の開発2022

    • Author(s)
      戸部 友輔: 本間 順:, 坂口 勝久, 関根 秀一, 岩﨑 清隆, 清水 達也
    • Organizer
      第21回日本再生医療学会
    • Data Source
      KAKENHI-PROJECT-19H04453
  • [Presentation] 生体外における吻合移植可能な膵島β細胞組織の構築2022

    • Author(s)
      矢後 博基, 本間 順, 関根 秀一, 清水 達也
    • Organizer
      第21回日本再生医療学会
    • Data Source
      KAKENHI-PROJECT-21K12654
  • [Presentation] 血管内皮細胞共培養膵島β細胞シートによる皮下での立体的膵島β細胞組織の構築2022

    • Author(s)
      本間 順, 関根 秀一, 清水 達也
    • Organizer
      第21回再生医療学会
    • Data Source
      KAKENHI-PROJECT-21K12654
  • [Presentation] In vivo vascularization for tissue and organ fabrication2019

    • Author(s)
      Hidekazu Sekine
    • Organizer
      TERMIS-AP 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H04453
  • [Presentation] Analysis of metabolic activity using the engineered heart tissue model2017

    • Author(s)
      Hidekazu Sekine, Tatsuya Shimizu
    • Organizer
      Keystonesymposia Mitochondria Communication
    • Place of Presentation
      Taos, New Mexico, USA
    • Year and Date
      2017-01-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350517
  • [Presentation] Ex vivo engineering of vascularized heart tissue model2016

    • Author(s)
      Hidekazu Sekine, Tatsuya Shimizu
    • Organizer
      European Chapter Meeting of the Tissue Engineering and Regenerative Medicine International Society 2016
    • Place of Presentation
      Uppsala, Sweden
    • Year and Date
      2016-06-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350517
  • [Presentation] Ex vivo fabrication of heart tissue model with perfusable blood vessels using cell sheet2016

    • Author(s)
      Hidekazu Sekine, Tatsuya Shimizu
    • Organizer
      Basic Cardiovascular Sciences (BCVS) Scientific Sessions 2016
    • Place of Presentation
      Phoenix, Arizona, USA
    • Year and Date
      2016-07-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350517
  • [Presentation] Fabrication of vascularized 3-D heart tissue model for drug evaluation2015

    • Author(s)
      Hidekazu Sekine, Tatsuya Shimizu
    • Organizer
      World Conference on Regenerative Medicine
    • Place of Presentation
      Congress Center Leipzig
    • Year and Date
      2015-10-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350517
  • [Presentation] The Model of Vascularized Three Dimensional Heart Tissue for Drug Evaluation2015

    • Author(s)
      Hidekazu Sekine, Tatsuya Shimizu
    • Organizer
      2015 4th TERMIS World Congress
    • Place of Presentation
      The Boston Marriott Copley Place
    • Year and Date
      2015-09-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350517
  • 1.  Homma Jun (50507366)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 18 results
  • 2.  SHIMIZU Tatsuya (40318100)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 3.  KOBAYASHI Eiji (00245044)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  Nakayama Masamichi (00338980)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  増田 信奈子 (30342851)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  原口 裕次 (80272251)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  秋元 淳 (80649682)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  遠山 周吾 (90528192)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  遠藤 祐輝 (10815195)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  佐々木 裕 (80349589)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 11.  横尾 隆 (70301538)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 12.  戸部 友輔 (00907082)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  劉 美憬
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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