KOGURE HIROFUMI 木暮宏史

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KOGURE Hirofumi 木暮宏史

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Researcher Number	60568921
Other IDs
Affiliation (Current)	2025: 日本大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 日本大学, 医学部, 教授 2012 – 2021: 東京大学, 医学部附属病院, 助教 2011: 東京大学, 医学部附属病院, 特任臨床医
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Gastroenterology
Keywords	Principal Investigator 肝内胆管癌 / 胆道癌 / 胆管癌 / エピジェネテイクス / 胆管がん / 胆道がん / ヒストン修飾 Except Principal Investigator 膵癌 / エピジェネテイクス / ヒストン修飾 / 膵がん

肝内胆管癌におけるエピゲノムaddictionの包括的解明Principal Investigator
- Principal Investigator
  
  木暮宏史
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Nihon University
  The University of Tokyo
Analysis of metabolic reprogramming in intrahepatic cholangiocellular carcinomaPrincipal Investigator
- Principal Investigator
  
  Kogure Hirofumi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  The University of Tokyo
Comprehensive analysis of IDH mutation in intrahepatic cholangio carcinomaPrincipal Investigator
- Principal Investigator
  
  Kogure Hirofumi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Application of genome informatics for the molecular targeting therapy against cholangiocarcinomaPrincipal Investigator
- Principal Investigator
  
  KOGURE Hirofumi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Identification of a histone modifier that affects pancreatic cancer progression
- Principal Investigator
  
  TATEISHI Keisuke
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019 2018 2017 2014 2013 2012 2011 Other

All Journal Article Other

[Journal Article] Gut-Microbiota Dysbiosis in Stroke-Prone Spontaneously Hypertensive Rats with Diet-Induced Steatohepatitis2023
- Author(s)
  Kanezawa Shini、Moriyama Mitsuhiko、Kanda Tatsuo、Fukushima Akiko、Masuzaki Ryota、Sasaki-Tanaka Reina、Tsunemi Akiko、Ueno Takahiro、Fukuda Noboru、Kogure Hirofumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 5 Pages: 4603-4603
- DOI
  10.3390/ijms24054603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07935
[Journal Article] Suppressors of Cytokine Signaling and Hepatocellular Carcinoma2022
- Author(s)
  Masuzaki Ryota、Kanda Tatsuo、Sasaki Reina、Matsumoto Naoki、Nirei Kazushige、Ogawa Masahiro、Karp Seth J.、Moriyama Mitsuhiko、Kogure Hirofumi
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 10 Pages: 2549-2549
- DOI
  10.3390/cancers14102549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07935
[Journal Article] A Prospective Multicenter Study of “Inside Stents” for Biliary Stricture: Multicenter Evolving Inside Stent Registry (MEISteR)2021
- Author(s)
  Kogure Hirofumi、Kato Hironari、Nakai Yousuke、Isayama Hiroyuki, et al.
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 10 Issue: 13 Pages: 2936-2936
- DOI
  10.3390/jcm10132936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07935, KAKENHI-PROJECT-21K07946
[Journal Article] 5-Aminolevulinic acid-mediated photodynamic activity in patient-derived cholangiocarcinoma organoids2020
- Author(s)
  Fujiwara Hiroaki、Takahara Naminatsu、Tateishi Keisuke、Tanaka Mariko、Kanai Sachiko、Kato Hiroyuki、Nakatsuka Takuma、Yamamoto Keisuke、Kogure Hirofumi、Arita Junichi、Nakai Yousuke、Kasuga Masato、Ushiku Tetsuo、Hasegawa Kiyoshi、Koike Kazuhiko
- Journal Title
  
  Surgical Oncology
  
  Volume: 35 Pages: 484-490
- DOI
  10.1016/j.suronc.2020.10.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08277, KAKENHI-PROJECT-19K17391, KAKENHI-PROJECT-18K07899
[Journal Article] Mutant IDH1 confers resistance to energy stress in normal biliary cells through PFKP-induced aerobic glycolysis and AMPK activation2019
- Author(s)
  Fujiwara H、Tateishi K、Misumi K、Hayashi A、Igarashi K、Kato H、Nakatsuka T、Suzuki N、Yamamoto K、Kudo Y、Hayakawa Y、Nakagawa 、Tanaka Y、Ijichi H、Kogure H、Nakai Y、Isayama H、Hasegawa K、Fukayama M、Soga T、Koike K
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 18859-18859
- DOI
  10.1038/s41598-019-55211-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07961, KAKENHI-PROJECT-19K17391, KAKENHI-PROJECT-19K17478, KAKENHI-PROJECT-17K09454, KAKENHI-PROJECT-18K07899, KAKENHI-PROJECT-18K07900
[Journal Article] Isocitrate dehydrogenase 1 mutation sensitizes intrahepatic cholangiocarcinoma to the BET inhibitor JQ12018
- Author(s)
  Fujiwara Hiroaki、Tateishi Keisuke、Kato Hiroyuki、Nakatsuka Takuma、Yamamoto Keisuke、Tanaka Yasuo、Ijichi Hideaki、Takahara Naminatsu、Mizuno Suguru、Kogure Hirofumi、Matsubara Saburo、Nakai Yousuke、Koike Kazuhiko
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 11 Pages: 3602-3610
- DOI
  10.1111/cas.13784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07899, KAKENHI-PROJECT-18K07961, KAKENHI-PROJECT-18K07962, KAKENHI-PROJECT-16K09342, KAKENHI-PROJECT-16K09390, KAKENHI-PROJECT-16K09391
[Journal Article] Second-line chemotherapy in patients with advanced or recurrent biliary tract cancer: a single center, retrospective analysis of 294 cases2018
- Author(s)
  Takahara Naminatsu、Nakai Yousuke、Isayama Hiroyuki、Sasaki Takashi、Saito Kei、Oyama Hiroki、Kanai Sachiko、Suzuki Tatsunori、Sato Tatsuya、Hakuta Ryunosuke、Ishigaki Kazunaga、Takeda Tsuyoshi、Saito Tomotaka、Mizuno Suguru、Kogure Hirofumi、Tada Minoru、Koike Kazuhiko
- Journal Title
  
  Investigational New Drugs
  
  Volume: 36 Issue: 6 Pages: 1093-1102
- DOI
  10.1007/s10637-018-0670-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09454, KAKENHI-PROJECT-18K07899
[Journal Article] Gemcitabine and S-1 versus gemcitabine and cisplatin treatment in patients with advanced biliary tract cancer: a multicenter retrospective study.2017
- Author(s)
  Takahara N, Isayama H, Nakai Y, Sasaki T, Ishigaki K, Saito K, Akiyama D, Uchino R, Mizuno S, Yagioka H, Kogure H, Togawa O, Matsubara S, Ito Y, Toda N, Tada M, Koike K.
- Journal Title
  
  Invest New Drugs
  
  Volume: 35(3) Issue: 3 Pages: 269-276
- DOI
  10.1007/s10637-017-0430-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09454, KAKENHI-PROJECT-15K09043
[Journal Article] CA19-9 kinetics during systemic chemotherapy in patients with advanced or recurrent biliary tract cancer.2017
- Author(s)
  Takahara N, Nakai Y, Isayama H, Sasaki T, Saito K, Noguchi K, Suzuki T, Nakamura T, Sato T, Ishigaki K, Hakuta R, Takeda T, Uchino R, Mizuno S, Kogure H, Tada M, Koike K.
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume: 80(6) Issue: 6 Pages: 1105-1112
- DOI
  10.1007/s00280-017-3456-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09454, KAKENHI-PROJECT-15K09043
[Journal Article] Disease-Specific Mortality Among Patients With Intraductal Papillary Mucinous Neoplasm of the Pancreas2014
- Author(s)
  Kawakubo K, Tada M, Isayama H, Sasahira N, Nakai Y, Takahara N, Uchino R, Hamada T, Miyabayashi K, Yamamoto K, Mizuno S, Mohri D, Kogure H, Sasaki T, Yamamoto N, Hirano K, Ijichi H, Tateishi K, Koike K
- Journal Title
  
  Clin Gastroenterol Hepatol
  
  Volume: 12(3) (2013 Jul 25) Issue: 3 Pages: 486-91
- DOI
  10.1016/j.cgh.2013.06.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591009, KAKENHI-PROJECT-23591010, KAKENHI-PROJECT-25860514
[Journal Article] Short- and long-term outcomes ofendoscopic papillary large balloon dilation with or without sphincterotomy for　removal of large bile duct stones.2014
- Author(s)
  Kogure H, Tsujino T, Isayama H, Takahara N, Uchino R, Hamada T, MiyabayashiK, Mizuno S, Mohri D, Yashima Y, Kawakubo K, Sasaki T, Yamamoto N, Nakai Y,Hirano K, Sasahira N, Tada M, Koike K.
- Journal Title
  
  Scand J Gastroenterol.
  
  Volume: ４９ Issue: 1 Pages: 121-128
- DOI
  10.3109/00365521.2013.848470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591006
[Journal Article] Clinical outcomes ofchemotherapy for diabetic and nondiabetic patients with pancreatic cancer: better prognosis with statin use in diabetic patients2013
- Author(s)
  Nakai Y, Isayama H, Sasaki T, Mizuno S, Sasahira N, Kogure H, Kawakubo K, Yamamoto N, Hirano K, Ijichi H, Tateishi K, Tada M, Koike K
- Journal Title
  
  Pancreas
  
  Volume: 42(2) Pages: 202-8
- Data Source
  KAKENHI-PROJECT-23591009
[Journal Article] A retrospective study of S-1 and oxaliplatin combination chemotherapy in patients with refractory pancreatic cancer2013
- Author(s)
  Takahara N, Isayama H, Nakai Y, Sasaki T, Hamada T, Uchino R, Mizuno S, Miyabayashi K, Kogure H, Yamamoto N, Sasahira N, Hirano K, Ijichi H, Tateishi K, Tada M, Koike K
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 72(5) Pages: 985-90
- Data Source
  KAKENHI-PROJECT-23591009
[Journal Article] A multicenter phase II trial of gemcitabine and candesartan combination therapy in patients with advanced pancreatic cancer: GECA22013
- Author(s)
  Nakai Y, Isayama H, Ijichi H, Sasaki T, Takahara N, Ito Y, Matsubara S, Uchino R, Yagioka H, Arizumi T, Hamada T, Miyabayashi K, Mizuno S, Yamamoto K, Kogure H, Yamamoto N, Hirano K, Sasahira N, Tateishi K, Tada M, Koike K
- Journal Title
  
  Invest New Drugs
  
  Volume: 31(5) Pages: 1294-9
- Data Source
  KAKENHI-PROJECT-23591009
[Journal Article] A retrospective analysis of early CA19-9 change in salvage chemotherapy for refractory pancreatic cancer2013
- Author(s)
  Nakai Y, Isayama H, Sasaki T, Takahara N, Hamada T, Uchino R, Mizuno S, Miyabayashi K, Yamamoto K, Mohri D, Kogure H, Yamamoto N, Hirano K, Ijichi H, Tateishi K, Tada M, Koike K
- Journal Title
  
  Cancer Chemother Pharmacol
- Data Source
  KAKENHI-PROJECT-23591009
[Journal Article] Risk factors and early signs of pancreatic cancer in diabetes: screening strategy based on diabetes onset age2013
- Author(s)
  Mizuno S, Nakai Y, Isayama H, Yanai A, Takahara N, Miyabayashi K, Yamamoto K, Kawakubo K, Mohri D, Kogure H, Sasaki T, Yamamoto N, Sasahira N, Hirano K, Tsujino T, Ijichi H, Tateishi K, Akanuma M, Tada M, Koike K
- Journal Title
  
  J Gastroenterol
  
  Volume: 48(2) Pages: 238-46
- NAID
  10031156309
- Data Source
  KAKENHI-PROJECT-23591009
[Journal Article] Diabetes is a useful diagnostic clue to improve the prognosis of pancreatic cancer2013
- Author(s)
  Mizuno S, Nakai Y, Isayama H, Takahara N, Miyabayashi K, Yamamoto K, Kawakubo K, Mohri D, Kogure H, Sasaki T, Yamamoto N, Sasahira N, Hirano K, Tsujino T, Ijichi H, Tateishi K, Tada M, Koike K
- Journal Title
  
  Pancreatology
  
  Volume: 13(3) Pages: 285-9
- Data Source
  KAKENHI-PROJECT-23591009
[Journal Article] Risk for mortality from causes other than pancreatic cancer in patients with intraductal papillary mucinous neoplasm of the pancreas2013
- Author(s)
  Kawakubo K, Tada M, Isayama H, Sasahira N, Nakai Y, Takahara N, Miyabayashi K, Yamamoto K, Mizuno S, Mohri D, Kogure H, Sasaki T, Yamamoto N, Tateishi R, Hirano K, Ijichi H, Tateishi K, Koike K
- Journal Title
  
  Pancreas
  
  Volume: 42(4) Issue: 4 Pages: 687-91
- DOI
  10.1097/mpa.0b013e318270ea97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591009, KAKENHI-PROJECT-23591010
[Journal Article] Lower incidence of biliary carcinoma in patients with primary sclerosing cholangitis and high serum levels of immunoglobulin E.2012
- Author(s)
  Hirano K, Tada M, Kogure H,, Koike K.,et.al.
- Journal Title
  
  Clin Gastroenterol Hepatol
  
  Volume: 10 Pages: 79-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591006
[Journal Article] Phase I trial of gemcitabine and candesartan combination therapy in normotensive patients with advanced pancreatic cancer: GECA12012
- Author(s)
  Nakai Y, Isayama H, Ijichi H, Sasaki T, Kogure H, Yagioka H, Miyabayashi K, Mizuno S, Yamamoto K, Mouri D, Kawakubo K, Yamamoto N, Hirano K, Sasahira N, Tateishi K, Tada M, Koike K
- Journal Title
  
  Cancer Sci
  
  Volume: 103(8) Pages: 1489-92
- Data Source
  KAKENHI-PROJECT-23591009
[Journal Article] Incidence of extrapancreatic malignancies in patients with intraductal papillary mucinous neoplasms of the pancreas2011
- Author(s)
  Kawakubo K, Tada M, Isayama H, Sasahira N, Nakai Y, Yamamoto K, Kogure H, Sasaki T, Hirano K, Ijichi H, Tateishi K, Yoshida H, Koike K
- Journal Title
  
  Gut
  
  Volume: 60(9) Pages: 1249-53
- Data Source
  KAKENHI-PROJECT-23591009
[Journal Article] Recent progress and limitations of chemotherapy for pancreatic and biliary tract cancers2011
- Author(s)
  Tada M, Nakai Y, Sasaki T, Hamada T, Nagano R, Mohri D, Miyabayashi K, Yamamoto K, Kogure H, Kawakubo K, Ito Y, Yamamoto N, Sasahira N, Hirano K, Ijichi H, Tateishi K, Isayama H, Omata M, Koike K
- Journal Title
  
  World J Clin Oncol
  
  Volume: 2(3) Pages: 158-163
- Data Source
  KAKENHI-PROJECT-23591009
[]
[]

1. TATEISHI Keisuke (20396948)

# of Collaborated Projects: 5 results

# of Collaborated Products: 13 results
2. SASAKI Takashi (10569106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
3. YAMAMOTO Natsuyo (40599578)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
4. 濱田毅 (90723461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 藤原弘明 (00814500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 工藤洋太郎 (90608358)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TANAKA Yasuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 建石良介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 高原楠昊

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

KOGURE HIROFUMI 木暮 宏史

KOGURE Hirofumi 木暮 宏史

Research Projects

Research Products

Co-Researchers

肝内胆管癌におけるエピゲノムaddictionの包括的解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of metabolic reprogramming in intrahepatic cholangiocellular carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive analysis of IDH mutation in intrahepatic cholangio carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Application of genome informatics for the molecular targeting therapy against cholangiocarcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of a histone modifier that affects pancreatic cancer progression

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Gut-Microbiota Dysbiosis in Stroke-Prone Spontaneously Hypertensive Rats with Diet-Induced Steatohepatitis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Suppressors of Cytokine Signaling and Hepatocellular Carcinoma2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Prospective Multicenter Study of “Inside Stents” for Biliary Stricture: Multicenter Evolving Inside Stent Registry (MEISteR)2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 5-Aminolevulinic acid-mediated photodynamic activity in patient-derived cholangiocarcinoma organoids2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mutant IDH1 confers resistance to energy stress in normal biliary cells through PFKP-induced aerobic glycolysis and AMPK activation2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Isocitrate dehydrogenase 1 mutation sensitizes intrahepatic cholangiocarcinoma to the BET inhibitor JQ12018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Second-line chemotherapy in patients with advanced or recurrent biliary tract cancer: a single center, retrospective analysis of 294 cases2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gemcitabine and S-1 versus gemcitabine and cisplatin treatment in patients with advanced biliary tract cancer: a multicenter retrospective study.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CA19-9 kinetics during systemic chemotherapy in patients with advanced or recurrent biliary tract cancer.2017

Author(s)

Journal Title

DOI

Data Source

KOGURE HIROFUMI 木暮宏史

KOGURE Hirofumi 木暮宏史

[Journal Article] Short- and long-term outcomes ofendoscopic papillary large balloon dilation with or without sphincterotomy for　removal of large bile duct stones.2014